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2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-

CAS No.:
2062-78-4
Catalog Number:
AG002AL1
Molecular Formula:
C28H29F2N3O
Molecular Weight:
461.5462
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
>98%(HPLC)powder
In Stock USA
United States
$60
- +
50mg
>98%(HPLC)powder
In Stock USA
United States
$82
- +
100mg
>98%(HPLC)powder
In Stock USA
United States
$136
- +
250mg
>98%(HPLC)powder
In Stock USA
United States
$223
- +
Product Description
Catalog Number:
AG002AL1
Chemical Name:
2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-
CAS Number:
2062-78-4
Molecular Formula:
C28H29F2N3O
Molecular Weight:
461.5462
MDL Number:
MFCD00055081
IUPAC Name:
3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
InChI:
InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
InChI Key:
YVUQSNJEYSNKRX-UHFFFAOYSA-N
SMILES:
Fc1ccc(cc1)C(c1ccc(cc1)F)CCCN1CCC(CC1)n1c(=O)[nH]c2c1cccc2
EC Number:
218-171-7
UNII:
1HIZ4DL86F
Properties
Complexity:
632  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
461.228g/mol
Formal Charge:
0
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
461.557g/mol
Monoisotopic Mass:
461.228g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
35.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
6.3  
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Effects of dopamine, apomorphine gamma-hydroxybutyric acid, haloperidol and pimozide on reflex bradycardia in rats. The Journal of pharmacology and experimental therapeutics 19800801
A new dosage schedule for pimozide in the acute stabilisation and maintenance treatment of psychosis. Acta psychiatrica Belgica 19800101
Biochemical and neuroendocrine approaches to a malignant syndrome of neuroleptics. Acta psychiatrica Belgica 19800101
Serum calcium and magnesium levels in schizophrenia. II. Possible relationship to extrapyramidal symptoms. Archives of general psychiatry 19791101
Pimozide in acute schizophrenia: a pilot study. Current medical research and opinion 19790101
Central action of narcotic analgesics. Part III. The role of endogenous noradrenaline in hyperactivity induced by morphine or fentanyl in mice. Polish journal of pharmacology and pharmacy 19780101
Stimulating action of sulpiride and pimozide on prolactin release. Effect on bromocriptine, L-dopa and metergoline administration. Acta endocrinologica 19771001
Mediation of enhanced reflex vagal bradycardia by L-dopa via central dopamine formation in dogs. Archives internationales de pharmacodynamie et de therapie 19770301
[Pimozide in non-psychotic elderly patients with behavioural disturbances. An open study (author's transl)]. Pharmakopsychiatrie, Neuro-Psychopharmakologie 19761101
On the anticataleptic action of cyproheptadine. Pharmacology, biochemistry, and behavior 19760801
Influence of WA-335, a factor which blocks serotonin receptors, on neuroleptic-induced catalepsy. Archivum immunologiae et therapiae experimentalis 19760101
Ascending catecholamine pathways and amphetamine-induced locomotor activity: importance of dopamine and apparent non-involvement of norepinephrine. Brain research 19750815
Tardive dyskinesia treated with pimozide. Journal of the neurological sciences 19750401
Metoclopramide and pimozide in Parkinson's disease and levodopa-induced dyskinesias. Journal of neurology, neurosurgery, and psychiatry 19750401
Catecholamine correlates of isolation-induced aggression in mice. European journal of pharmacology 19750301
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population. Acta psychiatrica Scandinavica 19750201
Aggression and central neurotransmitters. International review of neurobiology 19750101
Antagonistic effect of cyproheptadine on neuroleptic-induced catalepsy. Pharmacology, biochemistry, and behavior 19750101
The effect of 5-hydroxytrytamine synthesis inhibitors on neuroleptic-induced catalepsy in rats. Archivum immunologiae et therapiae experimentalis 19750101
Spontaneous oral dyskinesia. Results of treatment with tetrabenazine, pimozide, or both. Archives of neurology 19741101
Role of noradrenaline in levodopa reversal of reserpine akinesia. Brain research 19740913
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