Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-
Title | Journal |
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Human Y-Family DNA Polymerase κ Is More Tolerant to Changes in Its Active Site Loop than Its Ortholog Escherichia coli DinB. | Chemical research in toxicology 20171120 |
Binary and ternary binding affinities between exonuclease-deficient Klenow fragment (Kf-exo(-)) and various arylamine DNA lesions characterized by surface plasmon resonance. | Chemical research in toxicology 20120820 |
Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction. | Chemical communications (Cambridge, England) 20120714 |
Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. | Nature structural & molecular biology 20120601 |
Gram-scale chemical synthesis of 2'-deoxynucleoside-5'-o-triphosphates. | Current protocols in nucleic acid chemistry 20120601 |
A review of the virological efficacy of the 4 World Health Organization-recommended tenofovir-containing regimens for initial HIV therapy. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120315 |
Simple and sensitive microRNA labeling by terminal deoxynucleotidyl transferase. | Acta biochimica et biophysica Sinica 20120201 |
Simultaneous determination of deoxycytidine diphosphate and deoxycytidine triphosphate by capillary electrophoresis with transient isotachophoretic stacking: a sensitive monitoring method for ribonucleotide reductase activity. | Electrophoresis 20120201 |
Ribonucleotide reductase inhibition restores platinum-sensitivity in platinum-resistant ovarian cancer: a Gynecologic Oncology Group Study. | Journal of translational medicine 20120101 |
Association of HCV core antigen seropositivity with long-term mortality in patients on regular hemodialysis. | Nephron extra 20120101 |
Bone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosis. | PloS one 20120101 |
Dopamine inactivation efficacy related to functional DAT1 and COMT variants influences motor response evaluation. | PloS one 20120101 |
The dUTPase enzyme is essential in Mycobacterium smegmatis. | PloS one 20120101 |
Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. | PloS one 20120101 |
Importance of the C2, N7, and C8 positions to the mutagenic potential of 8-Oxo-2'-deoxyguanosine with two A family polymerases. | Biochemistry 20111213 |
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. | Nature 20111106 |
Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response. | Cell and tissue research 20110501 |
Limited dCTP availability accounts for mitochondrial DNA depletion in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). | PLoS genetics 20110301 |
Bypass of N²-ethylguanine by human DNA polymerase κ. | DNA repair 20110102 |
Reverse transcription of the pFOXC mitochondrial retroplasmids of Fusarium oxysporum is protein primed. | Mobile DNA 20110101 |
Genotypic and phenotypic modifications of Neisseria meningitidis after an accidental human passage. | PloS one 20110101 |
Stimulation of growth of the human gastric pathogen Helicobacter pylori by atmospheric level of oxygen under high carbon dioxide tension. | BMC microbiology 20110101 |
Susceptibility to primary angle closure glaucoma in Saudi Arabia: the possible role of mitochondrial DNA ancestry informative haplogroups. | Molecular vision 20110101 |
Screening of CYP1B1 and LTBP2 genes in Saudi families with primary congenital glaucoma: genotype-phenotype correlation. | Molecular vision 20110101 |
Pseudomonas syringae pv. actinidiae draft genomes comparison reveal strain-specific features involved in adaptation and virulence to Actinidia species. | PloS one 20110101 |
High level expression of Acidothermus cellulolyticus β-1, 4-endoglucanase in transgenic rice enhances the hydrolysis of its straw by cultured cow gastric fluid. | Biotechnology for biofuels 20110101 |
Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota. | The Journal of biological chemistry 20101224 |
Molecular and biomorphometrical identification of ovine babesiosis in iran. | Iranian journal of parasitology 20101201 |
Microwave-mediated synthesis of labeled nucleotides with utility in the synthesis of DNA probes. | Bioconjugate chemistry 20101020 |
Synthesis and early development of hexadecyloxypropylcidofovir: an oral antipoxvirus nucleoside phosphonate. | Viruses 20101001 |
Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase. | Biochemistry 20100706 |
Antiviral treatment of chronic hepatitis B virus (HBV) infections. | Viruses 20100601 |
Mutagenic potential of DNA glycation: miscoding by (R)- and (S)-N2-(1-carboxyethyl)-2'-deoxyguanosine. | Biochemistry 20100309 |
Polymerization by DNA polymerase eta is blocked by cis-diamminedichloroplatinum(II) 1,3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells. | Carcinogenesis 20100301 |
Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W. | Journal of molecular biology 20100205 |
Specific amino acid residues are involved in substrate discrimination and template binding of human REV1 protein. | Biochemical and biophysical research communications 20100205 |
Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells. | BMC biology 20100101 |
Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts. | Cancer cell international 20100101 |
In vivo trans-specific gene silencing in fungal cells by in planta expression of a double-stranded RNA. | BMC biology 20100101 |
Cotylenin A inhibits cell proliferation and induces apoptosis and PAX6 mRNA transcripts in retinoblastoma cell lines. | Molecular vision 20100101 |
Nelarabine in the treatment of refractory T-cell malignancies. | Clinical Medicine Insights. Oncology 20100101 |
Clinical and genetic characterization of a Danish family with North Carolina macular dystrophy. | Molecular vision 20100101 |
Single-nucleotide and long-patch base excision repair of DNA damage in plants. | The Plant journal : for cell and molecular biology 20091101 |
Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme. | The Journal of biological chemistry 20090925 |
Amino acid architecture that influences dNTP insertion efficiency in Y-family DNA polymerase V of E. coli. | Journal of molecular biology 20090918 |
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides. | Antimicrobial agents and chemotherapy 20090901 |
Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity. | The Biochemical journal 20090827 |
Fishing in the (deoxyribonucleotide) pool. | The Biochemical journal 20090827 |
Structure of the human Rev1-DNA-dNTP ternary complex. | Journal of molecular biology 20090724 |
Development of a sensitive and selective LC/MS/MS method for the simultaneous determination of intracellular 1-beta-D-arabinofuranosylcytosine triphosphate (araCTP), cytidine triphosphate (CTP) and deoxycytidine triphosphate (dCTP) in a human follicular lymphoma cell line. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090515 |
Y-Family DNA polymerases may use two different dNTP shapes for insertion: a hypothesis and its implications. | Journal of molecular graphics & modelling 20090401 |
The reopening rate of the fingers domain is a determinant of base selectivity for RB69 DNA polymerase. | Biochemistry 20090317 |
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts. | The Journal of biological chemistry 20090206 |
Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine. | PloS one 20090101 |
Paclitaxel alters the expression and specific activity of deoxycytidine kinase and cytidine deaminase in non-small cell lung cancer cell lines. | Journal of experimental & clinical cancer research : CR 20090101 |
Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia. | OncoTargets and therapy 20090101 |
Global hypomethylation of genomic DNA in cancer-associated myofibroblasts. | Cancer research 20081201 |
Gemcitabine and taxanes in metastatic breast cancer: a systematic review. | Therapeutics and clinical risk management 20081201 |
Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region. | Journal of molecular biology 20081003 |
Attenuation of vision loss and delay in apoptosis of photoreceptors induced by proinsulin in a mouse model of retinitis pigmentosa. | Investigative ophthalmology & visual science 20080901 |
Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1. | The Journal of biological chemistry 20080829 |
Development of bioluminescent pyrophosphate assay using pyruvate phosphate dikinase and its application to single-nucleotide polymorphism analysis. | Analytical biochemistry 20080801 |
Altered order of substrate binding by DNA polymerase X from African Swine Fever virus. | Biochemistry 20080729 |
Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase. | The FEBS journal 20080501 |
Nuclear magnetic resonance investigation of primer--template models: formation of a pyrimidine bulge upon misincorporation. | Biochemistry 20080415 |
Crystal structures of Streptococcus mutans 2'-deoxycytidylate deaminase and its complex with substrate analog and allosteric regulator dCTP x Mg2+. | Journal of molecular biology 20080314 |
Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis. | Journal of molecular biology 20080215 |
Structural insights into DNA lesion bypass. | Structure (London, England : 1993) 20080201 |
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. | Structure (London, England : 1993) 20080201 |
2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups. | The Journal of biological chemistry 20080125 |
Glutathione S-transferase M1 and T1 polymorphisms in Arab glaucoma patients. | Molecular vision 20080101 |
Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order. | Comparative and functional genomics 20080101 |
A new linker group for functionalization of nucleic acids. | Nucleic acids symposium series (2004) 20080101 |
Kinetics of dCTP incorporation opposite to 7,8-dihydro-8-oxoguanine with different 5' nearest neighbors by yeast polymerase eta. | Nucleic acids symposium series (2004) 20080101 |
Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta. | Science (New York, N.Y.) 20071109 |
NMR investigation of primer-template models: structural effect of sequence downstream of a thymine template on mutagenesis in DNA replication. | Biochemistry 20070814 |
Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide. | Nature chemical biology 20070801 |
Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances. | Human molecular genetics 20070615 |
8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins. | Nature 20070531 |
Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta. | Biophysical journal 20070501 |
Purification, crystallization and preliminary crystallographic analysis of deoxyuridine triphosphate nucleotidohydrolase from Arabidopsis thaliana. | Acta crystallographica. Section F, Structural biology and crystallization communications 20070501 |
Structure-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity. | Journal of molecular biology 20070309 |
Investigating the 'steric gate' of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by targeted insertion of unnatural amino acids. | Biochemistry 20070227 |
DNA polymerase beta catalytic efficiency mirrors the Asn279-dCTP H-bonding strength. | FEBS letters 20070220 |
Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides. | BMC structural biology 20070101 |
Methylation-dependent fragment separation: novel analysis of 5-methyl cytosine by capillary electrophoresis of amplified DNA using PCR incorporation of chemically modified dCTP. | Nucleosides, nucleotides & nucleic acids 20070101 |
Transfer of surface polymerase reaction products to a secondary platform with conservation of spatial registration. | Journal of the American Chemical Society 20060920 |
Joint use of small-angle X-ray and neutron scattering to study biological macromolecules in solution. | European biophysics journal : EBJ 20060901 |
Translesion synthesis across bulky N2-alkyl guanine DNA adducts by human DNA polymerase kappa. | The Journal of biological chemistry 20060728 |
Accumulation of FFA-1, the Xenopus homolog of Werner helicase, and DNA polymerase delta on chromatin in response to replication fork arrest. | Journal of biochemistry 20060701 |
Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. | Nature structural & molecular biology 20060701 |
An efficiently extended class of unnatural base pairs. | Journal of the American Chemical Society 20060531 |
Cellular pharmacology of gemcitabine. | Annals of oncology : official journal of the European Society for Medical Oncology 20060501 |
Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. | The Journal of biological chemistry 20060127 |
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. | PLoS biology 20060101 |
Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway. | BMC cancer 20060101 |
T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking. | BMC medical genetics 20060101 |
E-selectin S128R polymorphism and severe coronary artery disease in Arabs. | BMC medical genetics 20060101 |
Co-activator p120 is increased by gonadotropins in the rat ovary and enhances progesterone receptor activity. | Reproductive biology and endocrinology : RB&E 20060101 |
The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia. | British journal of cancer 20051212 |
Pre-steady-state kinetic characterization of the DinB homologue DNA polymerase of Sulfolobus solfataricus. | The Journal of biological chemistry 20051209 |
Transient state kinetic studies of the MutT-catalyzed nucleoside triphosphate pyrophosphohydrolase reaction. | Biochemistry 20051122 |
In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant. | Cancer research 20051015 |
Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. | Structure (London, England : 1993) 20051001 |
Rev1 employs a novel mechanism of DNA synthesis using a protein template. | Science (New York, N.Y.) 20050930 |
Four-color multiplex reverse transcription polymerase chain reaction--overcoming its limitations. | Analytical biochemistry 20050901 |
Regulation of 5' template usage and incorporation of noncognate nucleotides by human telomerase. | RNA (New York, N.Y.) 20050901 |
Comparison of functional properties of mammalian DNA polymerase lambda and DNA polymerase beta in reactions of DNA synthesis related to DNA repair. | Biochimica et biophysica acta 20050810 |
Motions of the fingers subdomain of klentaq1 are fast and not rate limiting: implications for the molecular basis of fidelity in DNA polymerases. | Molecular cell 20050805 |
Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate. | Biochemistry 20050802 |
Release of DNA from dendriplexes encapsulated in PLGA nanoparticles. | International journal of pharmaceutics 20050725 |
Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases. | Antiviral research 20050701 |
Resistance to 9-beta-D-arabinofuranosyl-2-fluoroadenine due to reduced incorporation into DNA from competition by excess deoxyadenosine triphosphate: implications for different sensitivities to nucleoside analogues. | International journal of hematology 20050601 |
Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools. | Biochemistry 20050503 |
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site. | Biochemistry 20050308 |
A new highly efficient photoreactive analogue of dCTP. Synthesis, characterization, and application in photoaffinity modification of DNA binding proteins. | Bioconjugate chemistry 20050101 |
Comparison study on PCR amplification of modified DNA by using various kinds of polymerase and modified nucleoside triphosphates. | Nucleic acids symposium series (2004) 20050101 |
Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs. | Journal of the International AIDS Society 20050101 |
Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu. | Biochemistry 20041102 |
Amidox, an inhibitor of ribonucleotide reductase, potentiates the action of Ara-C in HL-60 human promyelocytic leukemia cells. | Nucleosides, nucleotides & nucleic acids 20041001 |
[Lamivudine therapy for chronic hepatitis B]. | Nihon rinsho. Japanese journal of clinical medicine 20040801 |
Enhancement by effectors and substrate nucleotides of R1-R2 interactions in Escherichia coli class Ia ribonucleotide reductase. | The Journal of biological chemistry 20040723 |
Modulation of the 5'-deoxyribose-5-phosphate lyase and DNA synthesis activities of mammalian DNA polymerase beta by apurinic/apyrimidinic endonuclease 1. | The Journal of biological chemistry 20040611 |
5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T and 1298A-->C mutations are associated with DNA hypomethylation. | Journal of medical genetics 20040601 |
Expression of the pyrG gene determines the pool sizes of CTP and dCTP in Lactococcus lactis. | European journal of biochemistry 20040601 |
Antibodies to guanosine triphosphate misidentified as anti-double-stranded DNA antibodies in a patient with antinuclear antibody-negative lupus, due to buckling of insolubilized assay DNA. | Arthritis and rheumatism 20040501 |
Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV. | Biochemistry 20040224 |
Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates. | Molecular pharmacology 20040201 |
Frequency and voltage dependence of the dielectrophoretic trapping of short lengths of DNA and dCTP in a nanopipette. | Biophysical journal 20040201 |
Inhibitors of CTP biosynthesis potentiate the anti-human immunodeficiency virus type 1 activity of 3TC in activated peripheral blood mononuclear cells. | Antiviral research 20040101 |
Effect of mycophenolate mofetil on the pharmacokinetics of antiretroviral drugs and on intracellular nucleoside triphosphate pools. | Clinical pharmacokinetics 20040101 |
Melatonin promoted chemotaxins expression in lung epithelial cell stimulated with TNF-alpha. | Respiratory research 20040101 |
Antisense radiotherapy: targeting full-size mdrl mRNA with 125I-labelled oligonucleotides. | International journal of radiation biology 20040101 |
Tight binding of deoxyribonucleotide triphosphates to human thymidine kinase 2 expressed in Escherichia coli. Purification and partial characterization of its dimeric and tetrameric forms. | Biochemistry 20031230 |
Combination chemotherapy in advanced gastrointestinal cancers: ex vivo sensitivity to gemcitabine and mitomycin C. | British journal of cancer 20031215 |
Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA. | The Journal of biological chemistry 20031107 |
Cloning, expression, and purification of the His6-tagged hyper-thermostable dUTPase from Pyrococcus woesei in Escherichia coli: application in PCR. | Protein expression and purification 20030901 |
Structure of the bifunctional dCTP deaminase-dUTPase from Methanocaldococcus jannaschii and its relation to other homotrimeric dUTPases. | The Journal of biological chemistry 20030725 |
Structure of the large subunit of class Ib ribonucleotide reductase from Salmonella typhimurium and its complexes with allosteric effectors. | Journal of molecular biology 20030627 |
Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines. | British journal of cancer 20030616 |
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses. | The Journal of biological chemistry 20030523 |
Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity. | The Journal of biological chemistry 20030502 |
Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa. | Biochemistry 20030304 |
Introduction of the alpha-P-borano-group into deoxynucleoside triphosphates increases their selectivity to HIV-1 reverse transcriptase relative to DNA polymerases. | Nucleosides, nucleotides & nucleic acids 20030301 |
Zero-mode waveguides for single-molecule analysis at high concentrations. | Science (New York, N.Y.) 20030131 |
Incorporation of (alpha-P-borano)-2',3'-dideoxycytidine 5'-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase. | Nucleosides, nucleotides & nucleic acids 20030101 |
DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion. | FEBS letters 20021204 |
Interactions of enantiomers of 2',3'-didehydro-2',3'-dideoxy-fluorocytidine with wild type and M184V mutant HIV-1 reverse transcriptase. | Antiviral research 20021201 |
Excess dNTPs minimize RNA hydrolysis during reverse transcription. | BioTechniques 20021101 |
A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase. | Biochemistry 20020813 |
Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide. | Biochemical pharmacology 20020801 |
Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells. | Biochemical pharmacology 20020801 |
Recovery of cyanine-dye nucleotide triphosphates. | Analytical biochemistry 20020615 |
Comparison of in vivo efficacy of BCX-1777 and cyclosporin in xenogeneic graft-vs.-host disease: the role of dGTP in antiproliferative action of BCX-1777. | International immunopharmacology 20020601 |
Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-beta-D-arabinofuranosyl cytosine in a human T-lymphoblastic cell line. | International journal of cancer 20020401 |
The genome of bacteriophage phiKZ of Pseudomonas aeruginosa. | Journal of molecular biology 20020315 |
Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside. | Cell death and differentiation 20020201 |
Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation. | Journal of molecular biology 20020125 |
2-Amino-7-deazaadenine forms stable base pairs with cytosine and thymine. | Bioorganic & medicinal chemistry letters 20020107 |
Cyclopentenyl cytosine induces apoptosis and increases cytarabine-induced apoptosis in a T-lymphoblastic leukemic cell-line. | Leukemia research 20011001 |
Identification of nucleotides with identical fluorescent labels based on fluorescence polarization in surfactant solutions. | Analytical chemistry 20010915 |
Structures of complexes formed by HIV-1 reverse transcriptase at a termination site of DNA synthesis. | The Journal of biological chemistry 20010817 |
Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair. | The Journal of biological chemistry 20010706 |
Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs. | The Journal of biological chemistry 20010629 |
Cellular pharmacokinetics and pharmacodynamics of the deoxycytidine analog 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC). | Biochemical pharmacology 20010615 |
Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I. | Biochemistry 20010605 |
The effect of DNA structure on the catalytic efficiency and fidelity of human DNA polymerase beta on templates with platinum-DNA adducts. | The Journal of biological chemistry 20010601 |
Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide. | British journal of haematology 20010501 |
Orf135 from Escherichia coli Is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP. | The Journal of biological chemistry 20010223 |
DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change. | The Journal of biological chemistry 20010202 |
In vivo DNA analysis. | Methods in molecular biology (Clifton, N.J.) 20010101 |
[Reagents for modification of protein-nucleic acids complexes. II. Site-specific photomodification of DNA-polymerase beta complexes with primers elongated by the dCTP exo-N-substituted arylazido derivatives]. | Bioorganicheskaia khimiia 20010101 |
Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19990901 |
Characterization and mutational analysis of the helicase and NTPase activities of hepatitis C virus full-length NS3 protein. | The Journal of general virology 19990301 |
Lethal mutagenesis of HIV with mutagenic nucleoside analogs. | Proceedings of the National Academy of Sciences of the United States of America 19990216 |
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs. | Nucleic acids research 19990215 |
Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy. | Nucleosides & nucleotides 19990101 |
Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism. | Proceedings of the National Academy of Sciences of the United States of America 19981110 |
Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity. | Molecular pharmacology 19980801 |
Palindromic oligonucleotide-directed enzymatic determination of 2'-deoxythymidine 5'-triphosphate and 2'-deoxycytidine 5'-triphosphate in human cells. | Analytical biochemistry 19971001 |
Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay. | Biochemistry 19970204 |
Increased activation of the combination of 3'-azido-3'-deoxythymidine and 2'-deoxy-3'-thiacytidine in the presence of hydroxyurea. | Antimicrobial agents and chemotherapy 19970201 |
Chiral influences of feedback inhibition with dCTP on murine deoxycytidine kinase. | Nucleic acids symposium series 19970101 |
Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates. | The Journal of biological chemistry 19951006 |
Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs. | Antimicrobial agents and chemotherapy 19941001 |
Lack of synergy in the inhibition of HIV-1 reverse transcriptase by combinations of the 5'-triphosphates of various anti-HIV nucleoside analogs. | Antiviral research 19931201 |
Isosteres of the DNA polymerase inhibitor aphidicolin as potential antiviral agents against human herpes viruses. | Journal of medicinal chemistry 19931112 |
The biochemical basis for the differential anti-human immunodeficiency virus activity of two cis enantiomers of 2',3'-dideoxy-3'-thiacytidine. | The Journal of biological chemistry 19931105 |
RNA-stimulated NTPase activity associated with yellow fever virus NS3 protein expressed in bacteria. | Journal of virology 19930201 |
HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587. | Biochemical pharmacology 19920317 |
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine. | Molecular pharmacology 19901001 |
Antiretroviral activity, biochemistry, and pharmacokinetics of 3'-azido-2',3'-dideoxy-5-methylcytidine. | Annals of the New York Academy of Sciences 19900101 |
2'-Deoxycytidine protects normal human bone marrow progenitor cells in vitro against the cytotoxicity of 3'-azido-3'-deoxythymidine with preservation of antiretroviral activity. | Blood 19891101 |
Inhibition of HIV reverse transcriptase by 2',3'-dideoxynucleoside triphosphates. | Biochemical pharmacology 19871215 |
2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis. | Molecular pharmacology 19871201 |
The quantitative determination of 2'-deoxycytidine-5'-triphosphate in cell extracts by radioimmunoassay. | Analytical biochemistry 19860401 |
Two simple high-performance liquid chromatographic methods for simultaneous determination of 2'-deoxycytidine 5'-triphosphate and cytosine arabinoside 5'-triphosphate concentrations in biological samples. | Journal of chromatography 19821210 |