Home Other Building Blocks 4-Chlorobiphenyl

4-Chlorobiphenyl

CAS No.:
2051-62-9
Catalog Number:
AG0029UW
Molecular Formula:
C12H9Cl
Molecular Weight:
188.6529
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$50
- +
5g
98%
In Stock USA
United States
$125
- +
10g
98%
In Stock USA
United States
$188
- +
25g
98%
In Stock USA
United States
$350
- +
Product Description
Catalog Number:
AG0029UW
Chemical Name:
4-Chlorobiphenyl
CAS Number:
2051-62-9
Molecular Formula:
C12H9Cl
Molecular Weight:
188.6529
MDL Number:
MFCD00013640
IUPAC Name:
1-chloro-4-phenylbenzene
InChI:
InChI=1S/C12H9Cl/c13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H
InChI Key:
FPWNLURCHDRMHC-UHFFFAOYSA-N
SMILES:
Clc1ccc(cc1)c1ccccc1
EC Number:
218-127-7
UNII:
QA22Z3NGLU
NSC Number:
37066
UN Number:
3432
Properties
Complexity:
141  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
188.039g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
188.654g/mol
Monoisotopic Mass:
188.039g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.6  
Literature
Title Journal
Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes. Archives of toxicology 20160201
Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes. Toxicology letters 20150318
Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1. Chemico-biological interactions 20140405
Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin. Environmental health perspectives 20130601
[4-chlorobiphenyl and 4-chlorobenzoic acid biodegradation by Rhodococcus ruber P25]. Mikrobiologiia 20120101
Antioxidant compounds improved PCB-degradation by Burkholderia xenovorans strain LB400. Enzyme and microbial technology 20111210
Are luminescent bacteria suitable for online detection and monitoring of toxic compounds in drinking water and its sources? Analytical and bioanalytical chemistry 20110501
Humic acid and metal ions accelerating the dechlorination of 4-chlorobiphenyl by nanoscale zero-valent iron. Journal of environmental sciences (China) 20110101
New hydroxylated metabolites of 4-monochlorobiphenyl in whole poplar plants. Chemistry Central journal 20110101
An efficient organocatalytic method for constructing biaryls through aromatic C-H activation. Nature chemistry 20101201
Induction of cytochrome P450 1A1 in MCF-7 human breast cancer cells by 4-chlorobiphenyl (PCB3) and the effects of its hydroxylated metabolites on cellular apoptosis. Environment international 20101101
Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites. Environment international 20101101
2-(4-Chlorophenyl)benzo-1,4-quinone induced ROS-signaling inhibits proliferation in human non-malignant prostate epithelial cells. Environment international 20101101
Polyploidy-induction by dihydroxylated monochlorobiphenyls: structure-activity-relationships. Environment international 20101101
3-Methylcholanthrene (3-MC) and 4-chlorobiphenyl (PCB3) genotoxicity is gender-related in Fischer 344 transgenic rats. Environment international 20101101
4'-Chloro-biphenyl-3-yl 2,2,2-trichloro-ethyl sulfate. Acta crystallographica. Section E, Structure reports online 20100901
Hydroxylated metabolites of 4-monochlorobiphenyl and its metabolic pathway in whole poplar plants. Environmental science & technology 20100515
The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments. PloS one 20100101
Computational framework for predictive biodegradation. Biotechnology and bioengineering 20091215
Direct inhibition of ERK1/2 phosphorylation as a possible mechanism for the antiproliferative action of 3,4-diOH-PCB3 in the MCF-7 cell line. Toxicology letters 20091028
Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells. Toxicology and applied pharmacology 20091015
Kinetic study of hydrodechlorination of chlorobiphenyl with polymer-stabilized palladium nanoparticles in supercritical carbon dioxide. The journal of physical chemistry. A 20090910
Exploring QSAR and QAAR for inhibitors of cytochrome P450 2A6 and 2A5 enzymes using GFA and G/PLS techniques. European journal of medicinal chemistry 20090501
Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase. Chemical research in toxicology 20090101
Novel Tn4371-ICE like element in Ralstonia pickettii and genome mining for comparative elements. BMC microbiology 20090101
Reductive Dechlorination of Polychlorinated Biphenyls and Dibenzo-p-Dioxins in an Enrichment Culture Containing Dehalobacter Species. Microbes and environments 20090101
4'-Chloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta crystallographica. Section E, Structure reports online 20081201
Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free radical biology & medicine 20081015
Microbial transformation and degradation of polychlorinated biphenyls. Environmental pollution (Barking, Essex : 1987) 20080901
A low halogenated biphenyl (PCB3) increases CYP1A1 expression and activity via the estrogen receptor beta in the porcine ovary. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901
Semiquinone radicals from oxygenated polychlorinated biphenyls: electron paramagnetic resonance studies. Chemical research in toxicology 20080721
Xenobiotic geometry and media pH determine cytotoxicity through solubility. Chemical research in toxicology 20080501
Mutagenicity of 3-methylcholanthrene, pcb3, and 4-oh-pcb3 in the lung of transgenic bigblue rats. Environmental toxicology and pharmacology 20080301
Effects of estradiol, PCB3, and their hydroxylated metabolites on proliferation, cell cycle, and apoptosis of human breast cancer cells. Environmental toxicology and pharmacology 20080301
The missing link: Bordetella petrii is endowed with both the metabolic versatility of environmental bacteria and virulence traits of pathogenic Bordetellae. BMC genomics 20080101
Degradation and mineralization of 2-chloro-, 3-chloro- and 4-chlorobiphenyl by a newly characterized natural bacterial strain isolated from an electrical transformer fluid-contaminated soil. Journal of environmental sciences (China) 20080101
Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range. Biochemistry 20071218
Quinoid metabolites of 4-monochlorobiphenyl induce gene mutations in cultured Chinese hamster v79 cells. Toxicological sciences : an official journal of the Society of Toxicology 20071101
Expression of bacterial biphenyl-chlorobiphenyl dioxygenase genes in tobacco plants. Biotechnology and bioengineering 20070615
Pathways and products of the degradation of PCBs by the sodium dispersion method. Chemosphere 20070601
Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes. Chemico-biological interactions 20070501
Electrocatalytic hydrodechlorination of 4-chlorobiphenyl in aqueous solution using palladized nickel foam cathode. Chemosphere 20070401
Influence of fluoro-substitution on the planarity of 4-chlorobiphenyl (PCB 3). Acta crystallographica. Section B, Structural science 20070401
Characterization of two biphenyl dioxygenases for biphenyl/PCB degradation in A PCB degrader, Rhodococcus sp. strain RHA1. Bioscience, biotechnology, and biochemistry 20070401
4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats. Carcinogenesis 20070201
Response to (chloro)biphenyls of the polychlorobiphenyl-degrader Burkholderia xenovorans LB400 involves stress proteins also induced by heat shock and oxidative stress. FEMS microbiology letters 20070201
[Estimation of bioconcentration factor of benzene derivatives]. Ying yong sheng tai xue bao = The journal of applied ecology 20061201
Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary. Toxicology letters 20061025
Oxidative ring cleavage of low chlorinated biphenyl derivatives by fungi leads to the formation of chlorinated lactone derivatives. Chemosphere 20060701
In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: effects on sex hormone levels and aromatase activity. Toxicology letters 20060701
Characterization of the PCB substrate range of microbial dechlorination process LP. Environmental science & technology 20050901
Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors. Journal of medicinal chemistry 20050602
Elucidation of degradation mechanism of dioxins during mechanochemical treatment. Environmental science & technology 20050515
Quantitative structure-activity relationship analysis of inhibitors of the nicotine metabolizing CYP2A6 enzyme. Journal of medicinal chemistry 20050127
Comparison of the actions of 4-chlorobiphenyl and its hydroxylated metabolites on estradiol secretion by ovarian follicles in primary cells in culture. Reproductive toxicology (Elmsford, N.Y.) 20050101
Effect of sorbate planarity on environmental black carbon sorption. Environmental science & technology 20040701
Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model. Toxicological sciences : an official journal of the Society of Toxicology 20040501
Construction of transformant reporters carrying fused genes using pcbC promoter of Pseudomonas sp DJ-12 for detection of aromatic pollutants. Environmental monitoring and assessment 20040301
[Determination of tanshinone IIA in rat plasma and the pharmacokinetics by RP-HPLC method]. Yao xue xue bao = Acta pharmaceutica Sinica 20030501
Binding of polychlorinated biphenyls/metabolites to hemoglobin. Toxicology letters 20030430
DNA adducts in cultures of polychlorinated biphenyl-treated human hepatocytes. Toxicology and applied pharmacology 20030415
DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites. Chemico-biological interactions 20020220
Sonochemical desorption and destruction of 4-chlorobiphenyl from synthetic sediments. Environmental science & technology 20020115
A laboratory pilot study of thermal decontamination of soils polluted by PCBs. Comparison with thermogravimetric analysis. Waste management (New York, N.Y.) 20020101
Distribution and macromolecular binding of benzo[a]pyrene and two polychlorinated biphenyl congeners in female mice. Chemico-biological interactions 20010928
Adaptive and cross-protective responses of Pseudomonas sp. DJ-12 to several aromatics and other stress shocks. Current microbiology 20010901
Effects of selected polychlorinated biphenyl (PCB) congeners on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress. Biochemical pharmacology 20010801
Dechlorination of polychlorobiphenyls using NaBH(4) and NaBH(4)/LiCl at 120-310 degrees C in glyme solvents. Journal of hazardous materials 20010420
2,4,4'-trichlorobiphenyl increases STAT5 transcriptional activity. Molecular carcinogenesis 20010401
Polychlorinated biphenyl-induced effects on metabolic enzymes, AP-1 binding, vitamin E, and oxidative stress in the rat liver. Toxicology and applied pharmacology 20010301
Development of a Rhodococcus recombinant strain for degradation of products from anaerobic dechlorination of PCBs. Environmental science & technology 20010215
Dissemination of catabolic plasmids among desiccation-tolerant bacteria in soil microcosms. Applied biochemistry and biotechnology 20010101
A meta cleavage pathway for 4-chlorobenzoate, an intermediate in the metabolism of 4-chlorobiphenyl by Pseudomonas cepacia P166. Applied and environmental microbiology 19950201
Enhanced biodegradation of polychlorinated biphenyls after site-directed mutagenesis of a biphenyl dioxygenase gene. Applied and environmental microbiology 19931101
Properties