2,2-Dimethyl-1,3-dioxane-4,6-dione
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Self-assembled Pd6 open cage with triimidazole walls and the use of its confined nanospace for catalytic Knoevenagel- and Diels-Alder reactions in aqueous medium. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120924 |
Fluorinated alcohols as promoters for the metal-free direct substitution reaction of allylic alcohols with nitrogenated, silylated, and carbon nucleophiles. | The Journal of organic chemistry 20120907 |
Carbon-based leaving group in substitution reactions: functionalization of sp3-hybridized quaternary and tertiary benzylic carbon centers. | Organic letters 20120706 |
Catalytic enantioselective protonation of nitronates utilizing an organocatalyst chiral only at sulfur. | Journal of the American Chemical Society 20120606 |
Deuterium-labelled N-acyl-L-homoserine lactones (AHLs)--inter-kingdom signalling molecules--synthesis, structural studies, and interactions with model lipid membranes. | Analytical and bioanalytical chemistry 20120401 |
Flash flow pyrolysis: mimicking flash vacuum pyrolysis in a high-temperature/high-pressure liquid-phase microreactor environment. | The Journal of organic chemistry 20120302 |
6-[(2-Chloro-pyridin-5-ylmeth-yl)(eth-yl)-azan-yl]-4-(2-fluoro-phen-yl)-1-methyl-5-nitro-1,2,3,4-tetra-hydro-pyridin-2-one. | Acta crystallographica. Section E, Structure reports online 20120301 |
Radical cyclization cascades of unsaturated Meldrum's acid derivatives. | Organic letters 20120106 |
Stereochemical insignificance discovered in Acinetobacter baumannii quorum sensing. | PloS one 20120101 |
Short synthesis of ethyl 3-(3-aminophenyl)propanoate. | Archiv der Pharmazie 20111201 |
Pseudo-five-component reaction between 3-formylchromones, meldrum's acid, isocyanides and primary arylamines: diversity-oriented synthesis of novel chromone-containing peptidomimetics. | ACS combinatorial science 20111114 |
An energy efficient and facile synthesis of high molecular weight polyesters using ketenes. | Chemical communications (Cambridge, England) 20111014 |
Bis[N-cyclohexyl-1-(2-{1-[(cyclohexyl-amino)carbonyl]cyclohexyl}-3,5-dioxo-1,2-oxazolidin-4-yl)cyclopentanecarbox-amide] monohydrate. | Acta crystallographica. Section E, Structure reports online 20110901 |
5,5'-[(2,4-Dichloro-phen-yl)methyl-ene]bis-(2,2-dimethyl-1,3-dioxane-4,6-dione). | Acta crystallographica. Section E, Structure reports online 20110801 |
2,2-Dimethyl-5-(2,3,4-trimeth-oxy-benzyl-idene)-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20110801 |
5-(1H-Indol-3-yl-methyl-idene)-2,2-di-methyl-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20110701 |
Acetoxy Meldrum's acid: a versatile acyl anion equivalent in the Pd-catalyzed asymmetric allylic alkylation. | Organic letters 20110617 |
5-(3,4-Dimethyl-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20110601 |
2,2-Dimethyl-5-[(2-nitro-anilino)methyl-idene]-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20110501 |
2,2-Dimethyl-5-[(pyridin-2-yl-amino)-methyl-idene]-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20110201 |
2,2-Dimethyl-5-[(5-methyl-furan-2-yl)methyl-idene]-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20110201 |
Ultrasound-assisted one-pot, four component synthesis of 4-aryl 3,4-dihydropyridone derivatives. | Ultrasonics sonochemistry 20110101 |
Facile synthesis and biological evaluation of 3,3-diphenylpropanoyl piperazines as T-type calcium channel blockers. | Bioorganic & medicinal chemistry letters 20110101 |
Infrared assisted production of 3,4-dihydro-2(1H)-pyridones in solvent-free conditions. | International journal of molecular sciences 20110101 |
Synthesis of functionalized chromenes from Meldrum's acid, 4-hydroxycoumarin, and ketones or aldehydes. | Combinatorial chemistry & high throughput screening 20101101 |
(E)-2,2-Dimethyl-5-(3-phenyl-allyl-idene)-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20101101 |
Ketene functionalized polyethylene: control of cross-link density and material properties. | Journal of the American Chemical Society 20101027 |
5-(4-Hy-droxy-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20100901 |
5-(4-Fluoro-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20100901 |
Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents. | Bioorganic & medicinal chemistry 20100801 |
Short malonyl dehydro peptides as potential scaffolds for peptidomimetics by an efficient Knoevenagel reaction. | Amino acids 20100701 |
4-[2-(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-yl-idene)hydrazin-1-yl]benzo-nitrile. | Acta crystallographica. Section E, Structure reports online 20100701 |
rac-2-Methyl-3,4,5,6-tetra-hydro-2H-2,6-methano-1,3-benzoxazocin-4-one. | Acta crystallographica. Section E, Structure reports online 20100601 |
Meldrum's acids and 5-alkylidene Meldrum's acids in catalytic carbon-carbon bond-forming processes. | Accounts of chemical research 20100316 |
Synthesis of zwitterionic salts of pyridinium-Meldrum acid and barbiturate through unique four-component reactions. | Journal of combinatorial chemistry 20100308 |
Polymer synthesis: facilitating functionality. | Nature chemistry 20100301 |
A facile route to ketene-functionalized polymers for general materials applications. | Nature chemistry 20100301 |
Practical asymmetric conjugate alkynylation of Meldrum's acid-derived acceptors: access to chiral beta-alkynyl acids. | Journal of the American Chemical Society 20100120 |
Microwave-assisted solid phase conversion study of Meldrum's acid to ethylenetetracarboxylic dianhydride (C6O6). | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100101 |
Electrochemical oxidation of catechols in the presence of phenyl-Meldrum's acid. Synthesis and kinetic evaluation. | Chemical & pharmaceutical bulletin 20100101 |
4-(4-Chloro-phen-yl)-7,7-dimethyl-7,8-dihydro-4H-1-benzopyran-2,5(3H,6H)-dione. | Acta crystallographica. Section E, Structure reports online 20100101 |
Synthetic routes to pyrrolizine-1,5-dione derivatives by flash vacuum pyrolysis of amidomethylene derivatives of Meldrum's acid. | Organic & biomolecular chemistry 20091207 |
4-(4-Methoxy-phen-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetra-hydrochromene-2,5-dione. | Acta crystallographica. Section E, Structure reports online 20091201 |
Asymmetric synthesis of all-carbon benzylic quaternary stereocenters via conjugate addition to alkylidene and indenylidene Meldrum's acids. | The Journal of organic chemistry 20091120 |
Hydrogenolysis of unstrained carbon-carbon sigma bonds: stereoselective entry into benzylic tertiary centers. | Journal of the American Chemical Society 20091104 |
One hundred years of Meldrum's acid: advances in the synthesis of pyridine and pyrimidine derivatives. | Molecular diversity 20091101 |
6-Methyl-sulfanyl-4H-pyrimido[1,6-a]pyrimidin-4-one. | Acta crystallographica. Section E, Structure reports online 20091001 |
2,2-Dimethyl-5-(2-naphthyl-amino-methyl-ene)-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20091001 |
5-(2-Fluoro-benzyl-idene)-2,2-dimethyl-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20091001 |
2,2-Dimethyl-5-[(3-nitro-anilino)methyl-ene]-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20090901 |
A novel one-pot three-(in situ five-)component condensation reaction: an unexpected approach for the synthesis of tetrahydro-2,4-dioxo-1H-benzo[b][1,5]diazepine-3-yl-2-methylpropanamide derivatives. | Organic letters 20090806 |
5-[(4-Acetyl-phenyl)-aminomethyl-ene]-2,2-dimethyl-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20090601 |
5-[(3,4-Dimethoxy-benzyl)-aminomethyl-ene]-2,2-dimethyl-1,3-dioxane-4,6-dione. | Acta crystallographica. Section E, Structure reports online 20090601 |
Multi-catalysis cascade reactions based on the methoxycarbonylketene platform: diversity-oriented synthesis of functionalized non-symmetrical malonates for agrochemicals and pharmaceuticals. | Organic & biomolecular chemistry 20090521 |
A new domino autocatalytic reaction leading to polyfunctionalized spiro[5.5]undecanes and dispiro[4.2.5.2]pentadecanes. | Organic & biomolecular chemistry 20090521 |
7,14-Bis(4-methoxy-phen-yl)-11,11-dimethyl-1,4,10,12-tetra-oxa-dispiro-[4.2.5.2]penta-decane-9,13-dione. | Acta crystallographica. Section E, Structure reports online 20090501 |
7,14-Bis(4-bromo-phen-yl)-2,11,11-trimethyl-1,4,10,12-tetra-oxa-dispiro-[4.2.5.2]penta-decane-9,13-dione. | Acta crystallographica. Section E, Structure reports online 20090501 |
Chemical bonding and structure-reactivity correlation in Meldrum's acid: a combined experimental and theoretical electron density study. | The Journal of organic chemistry 20090320 |
Probing persistent intramolecular C-H...X (X = O, S, Br, Cl, and F) bonding in solution using benzyl Meldrum's acid derivatives. | The Journal of organic chemistry 20090206 |
New potential inhibitors of DNA topoisomerase. Part II: Design and synthesis of alpha-lapachone derivatives under microwave irradiation. | Bioorganic & medicinal chemistry letters 20090201 |
LAS0811: from combinatorial chemistry to activation of antioxidant response element. | Journal of biomedicine & biotechnology 20090101 |
4-Phenyl-1,2,3,4-tetra-hydro-pyrimido[1,2-a]benzimidazol-2-one. | Acta crystallographica. Section E, Structure reports online 20081101 |
Mechanism and regioselectivity of the cycloaddition of thiones derived from Meldrum's acid, malonates, or other dicarbonyls. | The Journal of organic chemistry 20081003 |
Meldrum's acid catalyzed reaction of tetracyanoethylene and aldehydes in water: a novel approach to arylidenemalononitrile. | Chemical & pharmaceutical bulletin 20081001 |
Asymmetric synthesis of carboxylic acid derivatives having an all-carbon alpha-quaternary center through Cu-catalyzed 1,4-addition of dialkylzinc reagents to 2-aryl acetate derivatives. | Organic letters 20080703 |
Novel isocyanide-based four-component reaction: a facile synthesis of fully substituted 3,4-dihydrocoumarin derivatives. | Organic letters 20080619 |
Kinetic study of electrochemically induced michael reactions of o-quinones with Meldrum's acid derivatives. Synthesis of highly oxygenated catechols. | The Journal of organic chemistry 20080502 |
Meldrum's acid and related compounds in the synthesis of natural products and analogs. | Chemical Society reviews 20080401 |
7-Chloro-4-(2,5-dichloro-phen-yl)-1-phenyl-1H-thio-chromeno[2,3-b]pyridine-2,5(3H,4H)-dione. | Acta crystallographica. Section E, Structure reports online 20080401 |
A novel method for the synthesis of substituted 3,4-dihydrocoumarin derivatives via isocyanide-based three-component reaction. | Molecular diversity 20080101 |
Ab initio structure determination of 5-anilinomethylene-2,2-dimethyl-1,3-dioxane-4,6-dione from laboratory powder data--a combined use of X-ray, molecular and solid-state DFT study. | Acta crystallographica. Section B, Structural science 20070601 |
Carboxyketenes, methyleneketenes, vinylketenes, oxetanediones, ynols, and ylidic ketenes from Meldrum's acid derivatives. | Organic & biomolecular chemistry 20070507 |
Studies on the synthesis of (-)-gymnodimine. Subunit synthesis and coupling. | The Journal of organic chemistry 20070302 |
Carboxyketenes from 4-hydroxy-1,3-oxazin-6-ones and Meldrum's acid derivatives. | The Journal of organic chemistry 20070216 |
Modular synthesis of tetrahydrofluorenones from 5-alkylidene Meldrum's acids. | The Journal of organic chemistry 20061222 |
Meldrum's acid-derived thione dienophile in a convergent and stereoselective synthesis of a tetracyclic quassinoid intermediate. | Organic letters 20060928 |
Inhibition of photosystem II electron transport by acyl derivatives of 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum's acid). | Biochimica et biophysica acta 20060701 |
Hydrolysis of alpha-alkyl-alpha-(methylthio)methylene Meldrum's acids. A kinetic and computational investigation of steric effects. | The Journal of organic chemistry 20060623 |
Three-component synthesis of dialkyl 2-(alkylimino-methylene)3- (2,2,5-trimethyl-4,6-dioxo-1,3-dioxan-5-yl)-succinates. | Molecular diversity 20060501 |
Synthesis of multi ring-fused 2-pyridones via an acyl-ketene imine cyclocondensation. | Organic letters 20060302 |
Synthesis of new amphiphilic dendrons bearing aliphatic hydrocarbon surface sectors and a monocarboxylic or dicarboxylic acid focal point. | Organic letters 20060202 |
Immobilized versus coated amylose tris(3,5-dimethylphenylcarbamate) chiral stationary phases for the enantioselective separation of cyclopropane derivatives by liquid chromatography. | Journal of chromatography. A 20060106 |
Total synthesis of (+/-)-taiwaniaquinol B via a domino intramolecular friedel-crafts acylation/carbonyl alpha-tert-alkylation reaction. | Journal of the American Chemical Society 20050928 |
Reactions of 3-formylchromone with active methylene and methyl compounds and some subsequent reactions of the resulting condensation products. | Molecules (Basel, Switzerland) 20050831 |
Catalytic, enantioselective, conjugate alkyne addition. | Journal of the American Chemical Society 20050713 |
Cycloaddition of delta2-thiazolines and acyl ketenes under acidic conditions results in bicyclic 1,3-oxazinones and not 6-acylpenams as earlier reported. | Organic letters 20050317 |
A Cyclopropabenzenylidenethenone (propadienone) via a new route to alkylidenecycloproparenes. | Organic letters 20050303 |
Meldrum's acids as acylating agents in the catalytic intramolecular Friedel-Crafts reaction. | The Journal of organic chemistry 20050218 |
One-pot synthesis and chiral analysis of cyclopropane derivatives. | Chirality 20050101 |
Procedure for the parallel preparation of 3-imidazo[1,2-a]pyridin-3-yl-propionic acid derivatives involving Meldrum's acid. | Journal of combinatorial chemistry 20050101 |
Rh(II)-catalyzed enantioselective cyclopropanation of olefins with dimethyl malonate via in situ generated phenyliodonium ylide. | Organic letters 20041111 |
Mechanistic evidence for an alpha-oxoketene pathway in the formation of beta-ketoamides/esters via Meldrum's acid adducts. | Journal of the American Chemical Society 20041013 |
Determination of acidity constants of enolisable compounds by capillary electrophoresis. | Analytical and bioanalytical chemistry 20041001 |
Gas-phase acidities of disubstituted methanes and of enols of carboxamides substituted by electron-withdrawing groups. | The Journal of organic chemistry 20040903 |
Rationale for the acidity of Meldrum's acid. Consistent relation of C-H acidities to the properties of localized reactive orbital. | The Journal of organic chemistry 20040625 |
Synthesis and X-ray crystal structure of the dolabellaauricularia peptide dolastatin 18. | The Journal of organic chemistry 20040611 |
Highly regio- and chemoselective palladium-catalyzed propargylallylation of activated olefins: a novel route to 1,7-enyne derivatives. | The Journal of organic chemistry 20040611 |
A reexamination of Biginelli-like multicomponent condensation reaction: one-pot regioselective synthesis of spiro heterobicyclic rings. | Molecular diversity 20040101 |
Asymmetric conjugate addition reactions of Meldrum's acid derived acceptors employing chiral phosphoramidite ligands. | Organic letters 20031127 |
Experimental and theoretical investigation of reversible interconversion, thermal reactions, and wavelength-dependent photochemistry of diazo Meldrum's acid and its diazirine isomer, 6,6-dimethyl-5,7-dioxa-1,2-diaza-spiro[2,5]oct-1-ene-4,8-dione. | Journal of the American Chemical Society 20031119 |
Novel synthetic approach to 6,7-dihydro-5H-imidazo[1,5-a]-pyrazin-8-ones. | Organic letters 20031016 |
C,O-dialkylation of Meldrum's acid: synthesis and reactivity of 1,3,7,7-tetramethyl-4H,10H-6,8,9-trioxa-2-thiabenz[f]azulen-5-one. | The Journal of organic chemistry 20030919 |
Organocatalytic asymmetric domino knoevenagel/diels-alder reactions: a bioorganic approach to the diastereospecific and enantioselective construction of highly substituted spiro[5,5]undecane-1,5,9-triones. | Angewandte Chemie (International ed. in English) 20030915 |
Stereoselective synthesis of optically active bicyclic beta-lactam carboxylic acids that target pilus biogenesis in pathogenic bacteria. | Organic & biomolecular chemistry 20030421 |
Palladium-catalyzed asymmetric addition of pronucleophiles to allenes. | Journal of the American Chemical Society 20030416 |
Wavelength-dependent photochemistry of Diazo Meldrum's acid and its spirocyclic isomer, Diazirino Meldrum's acid: Wolff rearrangement versus isomerization. | Journal of the American Chemical Society 20030212 |
Introducing a novel class of four-component reactions. | Molecular diversity 20030101 |
Diastereoselective conjugate additions to pi-allylmolybdenum complexes: a stereocontrolled route to 3,4,5-trisubstituted gamma-butyrolactones. | Organic letters 20020613 |
An enantioselective ketene-imine cycloaddition method for synthesis of substituted ring-fused 2-pyridinones. | The Journal of organic chemistry 20011005 |
Novel synthesis of bis(phosphonic acid)-steroid conjugates. | The Journal of organic chemistry 20010601 |
New insight on the origin of the unusual acidity of Meldrum's acid from ab initio and combined QM/MM simulation study. | Journal of the American Chemical Society 20010502 |