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Home Aminos Acetamide, 2-[(2,3-dihydro-1H-inden-2-yl)amino]-, hydrochloride (1:1)

Acetamide, 2-[(2,3-dihydro-1H-inden-2-yl)amino]-, hydrochloride (1:1)

CAS No.:
202914-18-9
Catalog Number:
AG0028JT
Molecular Formula:
C11H15ClN2O
Molecular Weight:
226.7026
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Product Description
Catalog Number:
AG0028JT
Chemical Name:
Acetamide, 2-[(2,3-dihydro-1H-inden-2-yl)amino]-, hydrochloride (1:1)
CAS Number:
202914-18-9
Molecular Formula:
C11H15ClN2O
Molecular Weight:
226.7026
MDL Number:
MFCD09840800
IUPAC Name:
2-(2,3-dihydro-1H-inden-2-ylamino)acetamide;hydrochloride
InChI:
InChI=1S/C11H14N2O.ClH/c12-11(14)7-13-10-5-8-3-1-2-4-9(8)6-10;/h1-4,10,13H,5-7H2,(H2,12,14);1H
InChI Key:
JPNNIRXUJSPGRM-UHFFFAOYSA-N
SMILES:
NC(=O)CNC1Cc2c(C1)cccc2.Cl
EC Number:
606-503-7
UNII:
YHA48V735B
Properties
Complexity:
203  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
226.087g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
226.704g/mol
Monoisotopic Mass:
226.087g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
55.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Indantadol, a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain. IDrugs : the investigational drugs journal 20070901
CHF3381, a N-methyl-D-aspartate receptor antagonist and monoamine oxidase-A inhibitor, attenuates secondary hyperalgesia in a human pain model. The journal of pain : official journal of the American Pain Society 20060801
CHF3381, a novel antinociceptive agent, attenuates capsaicin-induced pain in rats. European journal of pharmacology 20050920
Mechanistic pharmacokinetic and pharmacodynamic modeling of CHF3381 (2-[(2,3-dihydro-1H-inden-2-yl)amino]acetamide monohydrochloride), a novel N-methyl-D-aspartate antagonist and monoamine oxidase-A inhibitor in healthy subjects. The Journal of pharmacology and experimental therapeutics 20050501
Steady-state pharmacokinetics and pharmacodynamics of CHF3381, a novel antineuropathic pain agent, in healthy subjects. British journal of clinical pharmacology 20050401
CHF 3381. Drugs in R&D 20040101
Antinociceptive activity of the N-methyl-D-aspartate receptor antagonist N-(2-Indanyl)-glycinamide hydrochloride (CHF3381) in experimental models of inflammatory and neuropathic pain. The Journal of pharmacology and experimental therapeutics 20030801
Mechanisms of action of CHF3381 in the forebrain. British journal of pharmacology 20030801
Safety, pharmacokinetics, and pharmacodynamics of CHF 3381, a novel N-methyl-D-aspartate antagonist, after single oral doses in healthy subjects. Journal of clinical pharmacology 20030801
Neuroprotective activity of CHF3381, a putative N-methyl-D-aspartate receptor antagonist. Neuroreport 20021115
Anticonvulsant preclinical profile of CHF 3381: dopaminergic and glutamatergic mechanisms. Pharmacology, biochemistry, and behavior 20010901
Preclinical evaluation of CHF3381 as a novel antiepileptic agent. Neuropharmacology 20010601
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