7-Methylguanosine
Title | Journal |
---|---|
Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway. | RNA (New York, N.Y.) 20121001 |
Synthesis of N²-modified 7-methylguanosine 5'-monophosphates as nematode translation inhibitors. | Bioorganic & medicinal chemistry 20120801 |
Affinity resins containing enzymatically resistant mRNA cap analogs--a new tool for the analysis of cap-binding proteins. | RNA (New York, N.Y.) 20120701 |
Specific domains in yeast translation initiation factor eIF4G strongly bias RNA unwinding activity of the eIF4F complex toward duplexes with 5'-overhangs. | The Journal of biological chemistry 20120608 |
Exploring purine N7 interactions via atomic mutagenesis: the group I ribozyme as a case study. | RNA (New York, N.Y.) 20120601 |
E2F1-dependent methyl cap formation requires RNA pol II phosphorylation. | Cell cycle (Georgetown, Tex.) 20120601 |
Thriving under stress: selective translation of HIV-1 structural protein mRNA during Vpr-mediated impairment of eIF4E translation activity. | PLoS pathogens 20120301 |
Targeting Mnks for cancer therapy. | Oncotarget 20120201 |
Bioinformatics tools and novel challenges in long non-coding RNAs (lncRNAs) functional analysis. | International journal of molecular sciences 20120101 |
Chemical approaches for structure and function of RNA in postgenomic era. | Journal of nucleic acids 20120101 |
High-resolution melting analysis for the rapid detection of fluoroquinolone and streptomycin resistance in Mycobacterium tuberculosis. | PloS one 20120101 |
In vitro transcription and capping of Gaussia luciferase mRNA followed by HeLa cell transfection. | Journal of visualized experiments : JoVE 20120101 |
Functional and structural analysis of the internal ribosome entry site present in the mRNA of natural variants of the HIV-1. | PloS one 20120101 |
Influenza polymerase activity correlates with the strength of interaction between nucleoprotein and PB2 through the host-specific residue K/E627. | PloS one 20120101 |
The eIF4F and eIFiso4F Complexes of Plants: An Evolutionary Perspective. | Comparative and functional genomics 20120101 |
Versatility of RNA-Binding Proteins in Cancer. | Comparative and functional genomics 20120101 |
ATPase cycle and DNA unwinding kinetics of RecG helicase. | PloS one 20120101 |
Global Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression. | Frontiers in genetics 20120101 |
Pyruvate is the source of the two carbons that are required for formation of the imidazoline ring of 4-demethylwyosine. | Biochemistry 20111213 |
RAM/Fam103a1 is required for mRNA cap methylation. | Molecular cell 20111118 |
Periodic expression of Sm proteins parallels formation of nuclear Cajal bodies and cytoplasmic snRNP-rich bodies. | Histochemistry and cell biology 20111101 |
The state-of-the-art determination of urinary nucleosides using chromatographic techniques 'hyphenated' with advanced bioinformatic methods. | Analytical and bioanalytical chemistry 20111001 |
Coordinated destruction of cellular messages in translation complexes by the gammaherpesvirus host shutoff factor and the mammalian exonuclease Xrn1. | PLoS pathogens 20111001 |
Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies. | Biochimie 20110901 |
Transfer RNA-mediated regulation of ribosome dynamics during protein synthesis. | Nature structural & molecular biology 20110901 |
Synthesis of a new class of ribose functionalized dinucleotide cap analogues for biophysical studies on interaction of cap-binding proteins with the 5' end of mRNA. | Organic & biomolecular chemistry 20110807 |
An interaction between KSHV ORF57 and UIF provides mRNA-adaptor redundancy in herpesvirus intronless mRNA export. | PLoS pathogens 20110701 |
Dynamical insight into Caenorhabditis elegans eIF4E recognition specificity for mono-and trimethylated structures of mRNA 5' cap. | Journal of molecular modeling 20110401 |
A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis. | PLoS biology 20110301 |
Targeting translation dependence in cancer. | Oncotarget 20110201 |
Mutation and selection on the wobble nucleotide in tRNA anticodons in marine bivalve mitochondrial genomes. | PloS one 20110101 |
Genomic stability over 9 years of an isoniazid resistant Mycobacterium tuberculosis outbreak strain in Sweden. | PloS one 20110101 |
Determinants of translation efficiency and accuracy. | Molecular systems biology 20110101 |
Upstream molecular signaling pathways of p27(Kip1) expression in human breast cancer cells in vitro: differential effects of 4-hydroxytamoxifen and deficiency of either D-(+)-glucose or L-leucine. | Cancer cell international 20110101 |
Cap-independent translation promotes C. elegans germ cell apoptosis through Apaf-1/CED-4 in a caspase-dependent mechanism. | PloS one 20110101 |
Nuclear accumulation of an uncapped RNA produced by Drosha cleavage of a transcript encoding miR-10b and HOXD4. | PloS one 20110101 |
tRNA Modification and Genetic Code Variations in Animal Mitochondria. | Journal of nucleic acids 20110101 |
Identification of allele-specific RNAi effectors targeting genetic forms of Parkinson's disease. | PloS one 20110101 |
Identification and analysis of the RNA degrading complexes and machinery of Giardia lamblia using an in silico approach. | BMC genomics 20110101 |
Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1. | PloS one 20110101 |
MicroRNAs in Hepatobiliary and Pancreatic Cancers. | Frontiers in genetics 20110101 |
Thousands of Novel Transcripts Identified in Mouse Cerebrum, Testis, and ES Cells Based on ribo-minus RNA Sequencing. | Frontiers in genetics 20110101 |
A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA. | Scientific reports 20110101 |
RNA decay and RNA silencing in plants: competition or collaboration? | Frontiers in plant science 20110101 |
Myc up-regulates formation of the mRNA methyl cap. | Biochemical Society transactions 20101201 |
Regulation of influenza RNA polymerase activity and the switch between replication and transcription by the concentrations of the vRNA 5' end, the cap source, and the polymerase. | Biochemistry 20101130 |
Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways. | Molecular and cellular biology 20101001 |
Identification of a quality-control mechanism for mRNA 5'-end capping. | Nature 20100930 |
The 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway. | Molecular cell 20100924 |
Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies. | The FEBS journal 20100701 |
Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles. | Human molecular genetics 20100201 |
Regulation of mRNA cap methylation. | The Biochemical journal 20100115 |
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. | Cell metabolism 20100106 |
The Arc of synaptic memory. | Experimental brain research 20100101 |
Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition. | RNA (New York, N.Y.) 20100101 |
The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse. | PloS one 20100101 |
Upstream molecular signaling pathways of p27(Kip1) expression: effects of 4-hydroxytamoxifen, dexamethasone, and retinoic acids. | Cancer cell international 20100101 |
Heritability in the efficiency of nonsense-mediated mRNA decay in humans. | PloS one 20100101 |
Transfer RNA modifications and genes for modifying enzymes in Arabidopsis thaliana. | BMC plant biology 20100101 |
A conserved stem loop motif in the 5'untranslated region regulates transforming growth factor-β(1) translation. | PloS one 20100101 |
Expression analysis and knockdown of two antennal odorant-binding protein genes in Aedes aegypti. | Journal of insect science (Online) 20100101 |
Proteomic analysis of streptomycin resistant and sensitive clinical isolates of Mycobacterium tuberculosis. | Proteome science 20100101 |
A screen for RNA-binding proteins in yeast indicates dual functions for many enzymes. | PloS one 20100101 |
The role of molecular biology in the biomonitoring of human exposure to chemicals. | International journal of molecular sciences 20100101 |
Hepatitis C Virus Evasion from RIG-I-Dependent Hepatic Innate Immunity. | Gastroenterology research and practice 20100101 |
Mi-DISCOVERER: A bioinformatics tool for the detection of mi-RNA in human genome. | Bioinformation 20100101 |
Thermodynamic analysis of mRNA cap binding by the human initiation factor eIF4E via free energy perturbations. | Journal of the American Chemical Society 20091223 |
Influenza A: understanding the viral life cycle. | The Yale journal of biology and medicine 20091201 |
The GTPase activity of Escherichia coli FtsZ determines the magnitude of the FtsZ polymer bundling by ZapA in vitro. | Biochemistry 20091124 |
Comparative analysis of an experimental subcellular protein localization assay and in silico prediction methods. | Journal of molecular histology 20091001 |
TERRA: telomeric repeat-containing RNA. | The EMBO journal 20090902 |
Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma. | British journal of cancer 20090804 |
Mechanical and kinetic effects of shortened tropomyosin reconstituted into myofibrils. | Pflugers Archiv : European journal of physiology 20090801 |
Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. | Cell 20090723 |
PcrA helicase tightly couples ATP hydrolysis to unwinding double-stranded DNA, modulated by the initiator protein for plasmid replication, RepD. | Biochemistry 20090714 |
Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation. | Bioorganic & medicinal chemistry letters 20090401 |
The RNA polymerase dictates ORF1 requirement and timing of LINE and SINE retrotransposition. | PLoS genetics 20090401 |
Diverse role of three tyrosines in binding of the RNA 5' cap to the human nuclear cap binding complex. | Journal of molecular biology 20090116 |
Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer. | Journal of experimental & clinical cancer research : CR 20090101 |
The human Ago2 MC region does not contain an eIF4E-like mRNA cap binding motif. | Biology direct 20090101 |
Mechanisms employed by retroviruses to exploit host factors for translational control of a complicated proteome. | Retrovirology 20090101 |
Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection. | BMC cancer 20090101 |
microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells. | PloS one 20090101 |
Identification of gemin5 as a novel 7-methylguanosine cap-binding protein. | PloS one 20090101 |
MicroRNA profiling and head and neck cancer. | Comparative and functional genomics 20090101 |
Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa. | PloS one 20090101 |
EBNA3C interacts with Gadd34 and counteracts the unfolded protein response. | Virology journal 20090101 |
Effect of the phosphate substrate on drug-inhibitor binding to human purine nucleoside phosphorylase. | Archives of biochemistry and biophysics 20081215 |
The RACK1 signal anchor protein from Trypanosoma brucei associates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis. | Molecular microbiology 20081101 |
snoRNA, a novel precursor of microRNA in Giardia lamblia. | PLoS pathogens 20081101 |
Crystal structure of the RRM domain of poly(A)-specific ribonuclease reveals a novel m(7)G-cap-binding mode. | Journal of molecular biology 20081017 |
The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon. | The EMBO journal 20080820 |
Stacking efficiency and flexibility analysis of aromatic amino acids in cap-binding proteins. | Proteins 20080601 |
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS. | RNA (New York, N.Y.) 20080601 |
MicroRNA: An emerging therapeutic target and intervention tool. | International journal of molecular sciences 20080601 |
Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1. | Genes & development 20080515 |
Motor step size and ATP coupling efficiency of the dsDNA translocase EcoR124I. | The EMBO journal 20080507 |
Detection and localization of small nuclear ribonucleoproteins (snRNPs) in trypanosomatids using anti-m3G antibodies. | Japanese journal of infectious diseases 20080301 |
Biochemical characterization of Yin Yang 1-RNA complexes. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20080201 |
Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code. | PloS one 20080101 |
m7GTP alphaS is a strong and stable inhibitor of cap-dependent translation. | Nucleic acids symposium series (2004) 20080101 |
Identifying intrinsic and extrinsic determinants that regulate internal initiation of translation mediated by the FMR1 5' leader. | BMC molecular biology 20080101 |
piggyBac transposon mediated transgenesis of the human blood fluke, Schistosoma mansoni. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071101 |
Transcriptional networking cap-tures the 7SK RNA 5'-gamma-methyltransferase. | Molecular cell 20070817 |
The major 5' end of HIV type 1 RNA corresponds to G456. | AIDS research and human retroviruses 20070801 |
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. | The Journal of biological chemistry 20070511 |
Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria. | Molecular microbiology 20070201 |
Methylation: a regulator of HIV-1 replication? | Retrovirology 20070101 |
Conflict between translation initiation and elongation in vertebrate mitochondrial genomes. | PloS one 20070101 |
EcoTILLING for the identification of allelic variants of melon eIF4E, a factor that controls virus susceptibility. | BMC plant biology 20070101 |
Identification of modified residues in RNAs by reverse transcription-based methods. | Methods in enzymology 20070101 |
MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans. | BMC bioinformatics 20070101 |
Systematic identification of non-coding RNA 2,2,7-trimethylguanosine cap structures in Caenorhabditis elegans. | BMC molecular biology 20070101 |
Solid-supported synthesis of 5'-mRNA CAP-4 from Trypanosomatids. | Nucleosides, nucleotides & nucleic acids 20070101 |
Interactions of calf spleen purine nucleoside phosphorylase with formycin B and its aglycone - spectroscopic and kinetic studies. | Nucleosides, nucleotides & nucleic acids 20070101 |
Non-adenine based purines accelerate wound healing. | Purinergic signalling 20061101 |
Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decay. | RNA (New York, N.Y.) 20060701 |
Calcium-stimulated guanosine--inosine nucleosidase from yellow lupin (Lupinus luteus). | Phytochemistry 20060701 |
Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control. | British journal of cancer 20060605 |
Parallel evolution of the genetic code in arthropod mitochondrial genomes. | PLoS biology 20060501 |
An industrial process for selective synthesis of 7-methyl guanosine 5'-diphosphate: versatile synthon for synthesis of mRNA cap analogues. | Nucleosides, nucleotides & nucleic acids 20060301 |
VPg of murine norovirus binds translation initiation factors in infected cells. | Virology journal 20060101 |
The complete sequence of the mitochondrial genome of Nautilus macromphalus (Mollusca: Cephalopoda). | BMC genomics 20060101 |
'Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells'. | Cancer cell international 20060101 |
Mechanism and regulation of translation in C. elegans. | WormBook : the online review of C. elegans biology 20060101 |
The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro. | RNA (New York, N.Y.) 20051001 |
Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2). | The Journal of biological chemistry 20050916 |
A new yeast poly(A) polymerase complex involved in RNA quality control. | PLoS biology 20050601 |
Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis. | Proteins 20050515 |
The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells. | The EMBO journal 20050504 |
Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping. | Journal of molecular biology 20050408 |
Yeast-like mRNA capping apparatus in Giardia lamblia. | The Journal of biological chemistry 20050401 |
Translation initiation factor (eIF) 4B affects the rates of binding of the mRNA m7G cap analogue to wheat germ eIFiso4F and eIFiso4F.PABP. | Biochemistry 20050322 |
A mutant of eukaryotic protein synthesis initiation factor eIF4E(K119A) has an increased binding affinity for both m7G cap analogues and eIF4G peptides. | Biochemistry 20050322 |
[Simultaneous determination of 7-methylguanosine and mitomycin C by capillary electrophoresis with amperometric detection]. | Se pu = Chinese journal of chromatography 20050301 |
A competitive ELISA detecting 7-methylguanosine adduct induced by N-nitrosodimethylamine exposure. | Human & experimental toxicology 20050201 |
Phylogenetic analysis of eIF4E-family members. | BMC evolutionary biology 20050101 |
Kinetic properties of Cellulomonas sp. purine nucleoside phosphorylase with typical and non-typical substrates: implications for the reaction mechanism. | Nucleosides, nucleotides & nucleic acids 20050101 |
Deaggregation of eIF4E induced by mRNA 5' cap binding. | Nucleosides, nucleotides & nucleic acids 20050101 |
Synthesis and enzymatic characterization of methylene analogs of adenosine 5'-tetraphosphate (P4A). | Nucleosides, nucleotides & nucleic acids 20050101 |
Thermodynamics of mRNA 5' cap binding by eukaryotic translation initiation factor eIF4E. | Biochemistry 20041026 |
Chemical synthesis and binding activity of the trypanosomatid cap-4 structure. | RNA (New York, N.Y.) 20040901 |
Determination of the capped site sequence of mRNA based on the detection of cap-dependent nucleotide addition using an anchor ligation method. | DNA research : an international journal for rapid publication of reports on genes and genomes 20040831 |
Influence of electric charge variation at residues 209 and 159 on the interaction of eIF4E with the mRNA 5' terminus. | Biochemistry 20040511 |
Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites. | Genome biology 20040101 |
Backbone resonance assignment of human eukaryotic translation initiation factor 4E (eIF4E) in complex with 7-methylguanosine diphosphate (m7GDP) and a 17-amino acid peptide derived from human eIF4GII. | Journal of biomolecular NMR 20031101 |
Macrocyclic amines as catalysts of the hydrolysis of the triphosphate bridge of the mRNA 5'-cap structure. | Organic & biomolecular chemistry 20031007 |
Charge distribution in 7-methylguanine regarding cation-pi interaction with protein factor eIF4E. | Biophysical journal 20030901 |
Synthesis of novel mRNA 5' cap-analogues: dinucleoside P1, P3-tri-, P1, P4-tetra-, and P1, P5-pentaphosphates. | Nucleosides, nucleotides & nucleic acids 20030101 |
Dinucleoside monophosphates containing AZT and 1-methyladenosine or 7-methylguanosine. | Nucleosides, nucleotides & nucleic acids 20030101 |
Thermodynamics of 7-methylguanosine cation stacking with tryptophan upon mRNA 5' cap binding to translation factor eIF4E. | Nucleosides, nucleotides & nucleic acids 20030101 |
Binding studies of eukaryotic initiation factor eIF4E with novel mRNA dinucleotide cap analogues. | Nucleosides, nucleotides & nucleic acids 20030101 |
Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. | RNA (New York, N.Y.) 20021001 |
The 'cap-binding slot' of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap. | Biochemistry 20020618 |
Calf spleen purine nucleoside phosphorylase: complex kinetic mechanism, hydrolysis of 7-methylguanosine, and oligomeric state in solution. | Biochimica et biophysica acta 20020429 |
A procedure for analysis of stopped-flow transients for protein-ligand association. | Journal of biochemical and biophysical methods 20020418 |
Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic initiation factor 4E: biological importance of the C-terminal flexible region. | The Biochemical journal 20020315 |
Beyond the proteome: non-coding regulatory RNAs. | Genome biology 20020101 |
Poly(rC) binding proteins mediate poliovirus mRNA stability. | RNA (New York, N.Y.) 20010801 |
Transcriptional regulation of the rat eIF4E gene in cardiac muscle cells: the role of specific elements in the promoter region. | Gene 20010404 |
A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements. | The EMBO journal 20010301 |
The major transcription initiation site of the p27Kip1 gene is conserved in human and mouse and produces a long 5'-UTR. | BMC molecular biology 20010101 |