9H-Xanthene-9-propanoic acid, α-amino-α-[(1S,2S)-2-carboxycyclopropyl]-, (αS)-
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Perinatal exposure to low-dose of bisphenol A causes anxiety-like alteration in adrenal axis regulation and behaviors of rat offspring: a potential role for metabotropic glutamate 2/3 receptors. | Journal of psychiatric research 20150501 |
Pharmacological characterization of JNJ-40068782, a new potent, selective, and systemically active positive allosteric modulator of the mGlu2 receptor and its radioligand [3H]JNJ-40068782. | The Journal of pharmacology and experimental therapeutics 20130901 |
Synthesis and characterization of two PET radioligands for the metabotropic glutamate 1 (mGlu1) receptor. | Synapse (New York, N.Y.) 20121201 |
Depolarizing bipolar cell dysfunction due to a Trpm1 point mutation. | Journal of neurophysiology 20121101 |
mTOR activation is required for the antidepressant effects of mGluR₂/₃ blockade. | The international journal of neuropsychopharmacology 20120501 |
Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses. | Scientific reports 20120101 |
Development of GPCR modulation of GABAergic transmission in chicken nucleus laminaris neurons. | PloS one 20120101 |
Group II metabotropic glutamate receptors depress synaptic transmission onto subicular burst firing neurons. | PloS one 20120101 |
Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists. | Neuropharmacology 20111201 |
Excitatory amino acid transporter 2 and excitatory amino acid transporter 1 negatively regulate calcium-dependent proliferation of hippocampal neural progenitor cells and are persistently upregulated after injury. | The European journal of neuroscience 20111201 |
Estradiol attenuates the adenosine triphosphate-induced increase of intracellular calcium through group II metabotropic glutamate receptors in rat dorsal root ganglion neurons. | Journal of neuroscience research 20111101 |
Activation of group II metabotropic glutamate receptors induces long-term depression of excitatory synaptic transmission in the substantia nigra pars reticulata. | Neuroscience letters 20111024 |
Blockade of GABA(B) receptors facilitates evoked neurotransmitter release at spinal dorsal horn synapse. | Neuroscience 20111013 |
Group II/III metabotropic glutamate receptors exert endogenous activity-dependent modulation of TRPV1 receptors on peripheral nociceptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110907 |
Functional coupling between metabotropic glutamate receptors and G-proteins in rat cerebral cortex assessed by guanosine-5'-O-(3-[(35)S]thio)triphosphate binding assay. | Basic & clinical pharmacology & toxicology 20110901 |
The role of 5-hydroxytryptamine 7 receptors in the phencyclidine-induced novel object recognition deficit in rats. | The Journal of pharmacology and experimental therapeutics 20110801 |
A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110706 |
Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain. | Molecular pharmacology 20110701 |
Regulation of Akt and Wnt signaling by the group II metabotropic glutamate receptor antagonist LY341495 and agonist LY379268. | Journal of neurochemistry 20110601 |
Group II metabotropic glutamate receptors in the striatum of non-human primates: dysregulation following chronic cocaine self-administration. | Neuroscience letters 20110527 |
Baclofen and adenosine inhibition of synaptic transmission at CA3-CA1 synapses display differential sensitivity to K+ channel blockade. | Cellular and molecular neurobiology 20110501 |
Postsynaptic and presynaptic group II metabotropic glutamate receptor activation reduces neuronal excitability in rat midline paraventricular thalamic nucleus. | The Journal of pharmacology and experimental therapeutics 20110301 |
Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective. | Molecular pharmacology 20110301 |
Metabotropic glutamate receptor blockade in nucleus accumbens shell shifts affective valence towards fear and disgust. | The European journal of neuroscience 20110201 |
Orally active glutamate carboxypeptidase II inhibitor 2-MPPA attenuates dizocilpine-induced prepulse inhibition deficits in mice. | Brain research 20110131 |
AMPA receptor mediates mGlu 2/3 receptor antagonist-induced dopamine release in the rat nucleus accumbens shell. | Neurochemistry international 20101101 |
Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats. | European journal of pharmacology 20100810 |
Pharmacological effects of metabotropic glutamate receptor ligands on prepulse inhibition in DBA/2J mice. | European journal of pharmacology 20100810 |
Metabotropic glutamate receptors modulate glutamatergic and GABAergic synaptic transmission in the central nucleus of the inferior colliculus. | Brain research 20100414 |
Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100317 |
Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats. | European journal of pharmacology 20100210 |
Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage. | Neuroscience bulletin 20100201 |
Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. | Journal of neurochemistry 20100101 |
Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala. | The European journal of neuroscience 20091203 |
Involvement of Group II mGluRs in mossy fiber LTD. | Synapse (New York, N.Y.) 20091201 |
Neuroprotective effects of group II metabotropic glutamate receptor agonist DCG-IV on hippocampal neurons in transient forebrain ischemia. | Neuroscience letters 20090925 |
gamma-Aminobutyric acid-mediated regulation of the activity-dependent olfactory bulb dopaminergic phenotype. | Journal of neuroscience research 20090801 |
Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice. | Molecular pharmacology 20090801 |
Antinociceptive synergistic effect of spinal mGluR2/3 antagonist and glial cells inhibitor on peripheral inflammation-induced mechanical hypersensitivity. | Brain research bulletin 20090529 |
A transient receptor potential-like channel mediates synaptic transmission in rod bipolar cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090513 |
Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain. | Molecular pharmacology 20090501 |
Metabotropic glutamate receptor II in the brains of Parkinsonian patients. | Journal of neuropathology and experimental neurology 20090401 |
The slow Ca2+ -dependent K+ -current facilitates synchronization of hyperexcitable pyramidal neurons. | Brain research 20090203 |
Group II metabotropic glutamate receptor activation on peripheral nociceptors modulates TRPV1 function. | Brain research 20090112 |
Dynamic metabotropic control of intrinsic firing in cerebellar unipolar brush cells. | Journal of neurophysiology 20081201 |
GABA(B) receptor activation mediates frequency-dependent plasticity of developing GABAergic synapses. | Nature neuroscience 20081201 |
AMPA silencing is a prerequisite for developmental long-term potentiation in the hippocampal CA1 region. | Journal of neurophysiology 20081101 |
Repeated exposure to cocaine alters the modulation of mesocorticolimbic glutamate transmission by medial prefrontal cortex Group II metabotropic glutamate receptors. | Journal of neurochemistry 20081001 |
Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression. | European journal of pharmacology 20080911 |
Allosteric potentiators of metabotropic glutamate receptor subtype 1a differentially modulate independent signaling pathways in baby hamster kidney cells. | Neuropharmacology 20080901 |
Blockade of group II metabotropic glutamate receptors produces hyper-locomotion in cocaine pre-exposed rats by interactions with dopamine receptors. | Neuropharmacology 20080901 |
Conformational change of the transmembrane helices II and IV of metabotropic glutamate receptor involved in G protein activation. | Journal of neurochemistry 20080701 |
Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states. | Neuroscience 20080623 |
Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080601 |
Face-washing behavior induced by the group I metabotropic glutamate receptor agonist (S)-3,5-DHPG in mice is mediated by mGlu1 receptor. | European journal of pharmacology 20080531 |
Involvement of group I mGluRs in LTP induced by strong high frequency stimulation in the dentate gyrus in vitro. | Neuroscience letters 20080509 |
Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-1-fluorocyclopropanecarboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist. | Bioorganic & medicinal chemistry 20080415 |
A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors. | Molecular pharmacology 20080401 |
Group III mGluR regulation of synaptic transmission at the SC-CA1 synapse is developmentally regulated. | Neuropharmacology 20080401 |
Distinct neural mechanisms mediate olfactory memory formation at different timescales. | Learning & memory (Cold Spring Harbor, N.Y.) 20080301 |
Basal ganglia group II metabotropic glutamate receptors specific binding in non-human primate model of L-Dopa-induced dyskinesias. | Neuropharmacology 20080201 |
Glutamate spillover modulates GABAergic synaptic transmission in the rat midbrain periaqueductal grey via metabotropic glutamate receptors and endocannabinoid signaling. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080123 |
Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice. | Alcoholism, clinical and experimental research 20080101 |
Dual GABAergic synaptic response of fast excitation and slow inhibition in the medial habenula of rat epithalamus. | Journal of neurophysiology 20070901 |
A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. | Molecular pharmacology 20070801 |
In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders. | Psychopharmacology 20070701 |
A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors. | The Journal of pharmacology and experimental therapeutics 20070701 |
Group II metabotropic glutamate receptors inhibit glutamate release at thalamocortical synapses in the developing somatosensory cortex. | Neuroscience 20070525 |
The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task. | Neuropharmacology 20070301 |
Pharmacological activation of mGlu2/3 metabotropic glutamate receptors protects retinal neurons against anoxic damage in the goldfish Carassius auratus. | Experimental eye research 20070301 |
Effects of metabotropic glutamate 2/3 receptor antagonists in the stress-induced hyperthermia test in singly housed mice. | Psychopharmacology 20070201 |
Habituation deficits induced by metabotropic glutamate receptors 2/3 receptor blockade in mice: reversal by antipsychotic drugs. | The Journal of pharmacology and experimental therapeutics 20070201 |
Endogenous mGluR activity suppresses GABAergic transmission in avian cochlear nucleus magnocellularis neurons. | Journal of neurophysiology 20070201 |
Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats. | European journal of pharmacology 20070112 |
Group III metabotropic glutamate receptor agonists selectively suppress excitatory synaptic currents in the rat prefrontal cortex induced by 5-hydroxytryptamine2A receptor activation. | The Journal of pharmacology and experimental therapeutics 20070101 |
Participation of peripheral group I and II metabotropic glutamate receptors in the development or maintenance of IL-1beta-induced mechanical allodynia in the orofacial area of conscious rats. | Neuroscience letters 20061206 |
Blockade of group II metabotropic glutamate receptors in the nucleus accumbens produces hyperlocomotion in rats previously exposed to amphetamine. | Neuropharmacology 20061001 |
Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain. | Current biology : CB 20060822 |
Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060816 |
Unique presynaptic and postsynaptic roles of Group II metabotropic glutamate receptors in the modulation of thalamic network activity. | Neuroscience 20060811 |
Pharmacological stimulation of group ii metabotropic glutamate receptors reduces cocaine self-administration and cocaine-induced reinstatement of drug seeking in squirrel monkeys. | The Journal of pharmacology and experimental therapeutics 20060801 |
Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice. | The Journal of pharmacology and experimental therapeutics 20060701 |
Olfactory nerve-evoked, metabotropic glutamate receptor-mediated synaptic responses in rat olfactory bulb mitral cells. | Journal of neurophysiology 20060401 |
Differential roles for group 1 mGluR subtypes in induction and expression of chemically induced hippocampal long-term depression. | Journal of neurophysiology 20060401 |
Metabotropic glutamate receptor antagonists selectively enhance responses of slowly adapting type I mechanoreceptors. | Synapse (New York, N.Y.) 20060315 |
A temporally distinct role for group I and group II metabotropic glutamate receptors in object recognition memory. | Learning & memory (Cold Spring Harbor, N.Y.) 20060301 |
Antinociceptive effects and synergistic interaction with morphine of intrathecal metabotropic glutamate receptor 2/3 antagonist in the formalin test of rats. | Neuroscience letters 20060220 |
Differential negative coupling of type 3 metabotropic glutamate receptor to cyclic GMP levels in neurons and astrocytes. | Journal of neurochemistry 20060201 |
Long-term depression of NMDA receptor-mediated synaptic transmission is dependent on activation of metabotropic glutamate receptors and is altered to long-term potentiation by low intracellular calcium buffering. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125 |
Modulation of excitatory synaptic transmission by endogenous glutamate acting on presynaptic group II mGluRs in rat substantia nigra compacta. | Journal of neuroscience research 20051215 |
Regulation of IPSP theta rhythm by muscarinic receptors and endocannabinoids in hippocampus. | Journal of neurophysiology 20051201 |
Neuroprotective effect of N-acetyl-aspartyl-glutamate in combination with mild hypothermia in the endothelin-1 rat model of focal cerebral ischaemia. | Journal of neurochemistry 20051201 |
2-MPPA, a selective glutamate carboxypeptidase II inhibitor, attenuates morphine tolerance but not dependence in C57/Bl mice. | Psychopharmacology 20051201 |
Role of group II metabotropic glutamate receptors 2/3 and group I metabotropic glutamate receptor 5 in developing rat medial vestibular nuclei. | Neuroreport 20050822 |
Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050706 |
Presynaptic inhibition of corticothalamic feedback by metabotropic glutamate receptors. | Journal of neurophysiology 20050701 |
Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo. | Neuro-oncology 20050701 |
Neuropharmacological profiles of antagonists of group II metabotropic glutamate receptors. | Neuroscience letters 20050422 |
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models. | The Journal of pharmacology and experimental therapeutics 20050401 |
Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice. | Psychopharmacology 20050401 |
Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate. | Experimental neurology 20050401 |
Developmental switch in synaptic mechanisms of hippocampal metabotropic glutamate receptor-dependent long-term depression. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050316 |
The metabotropic glutamate (mGLU)2/3 receptor antagonist LY341495 [2S-2-amino-2-(1S,2S-2-carboxycyclopropyl-1-yl)-3-(xanth-9-yl)propanoic acid] stimulates waking and fast electroencephalogram power and blocks the effects of the mGLU2/3 receptor agonist ly379268 [(-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate] in rats. | The Journal of pharmacology and experimental therapeutics 20050201 |
Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus. | Neuropharmacology 20050101 |
Group II and III mGluRs-mediated presynaptic inhibition of EPSCs recorded from hippocampal interneurons of CA1 stratum lacunosum moleculare. | Neuropharmacology 20050101 |
Comparison of c-Fos induction in the brain by the mGlu2/3 receptor antagonist LY341495 and agonist LY354740: evidence for widespread endogenous tone at brain mGlu2/3 receptors in vivo. | Neuropharmacology 20050101 |
The preferential mGlu2/3 receptor antagonist, LY341495, reduces the frequency of spike-wave discharges in the WAG/Rij rat model of absence epilepsy. | Neuropharmacology 20050101 |
Metabotropic glutamate receptors modulate feedback inhibition in a developmentally regulated manner in rat dentate gyrus. | The Journal of physiology 20041201 |
Glutamate transporters and metabotropic receptors regulate excitatory neurotransmission in the medial entorhinal cortex of the rat. | Brain research 20041119 |
Glutamate-evoked alterations of glial and neuronal cell morphology in the guinea pig retina. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110 |
Activation of Group II and Group III metabotropic glutamate receptors by endogenous ligand(s) and the modulation of synaptic transmission in the superficial superior colliculus. | Neuropharmacology 20041101 |
Distinct properties of carbachol- and DHPG-induced network oscillations in hippocampal slices. | Neuropharmacology 20040901 |
Synthesis, in vitro pharmacology, structure-activity relationships, and pharmacokinetics of 3-alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent and selective group II metabotropic glutamate receptor antagonists. | Journal of medicinal chemistry 20040826 |
Tonic activity of metabotropic glutamate receptors is involved in developmental modification of short-term plasticity in the neocortex. | Journal of neurophysiology 20040801 |
Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model. | The European journal of neuroscience 20040701 |
Retroinhibition of presynaptic Ca2+ currents by endocannabinoids released via postsynaptic mGluR activation at a calyx synapse. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040630 |
Modulation of glutamate mobility reveals the mechanism underlying slow-rising AMPAR EPSCs and the diffusion coefficient in the synaptic cleft. | Neuron 20040610 |
Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat. | The European journal of neuroscience 20040501 |
Distinct properties of presynaptic group II and III metabotropic glutamate receptor-mediated inhibition of perforant pathway-CA1 EPSCs. | The European journal of neuroscience 20040501 |
The selective mGlu2/3 receptor antagonist LY341495 exacerbates behavioral signs of morphine withdrawal and morphine-withdrawal-induced activation of locus coeruleus neurons. | Neuropharmacology 20040401 |
Group II metabotropic glutamate receptors inhibit cAMP-dependent protein kinase-mediated enhancemednt of tetrodotoxin-resistant sodium currents in mouse dorsal root ganglion neurons. | Neuroscience letters 20040311 |
An NMDAR-independent LTP mediated by group II metabotropic glutamate receptors and p42/44 MAP kinase in the dentate gyrus in vitro. | Neuropharmacology 20040301 |
Selective transmission of single photon responses by saturation at the rod-to-rod bipolar synapse. | Neuron 20040205 |
Inhibitory effects of group II mGluR-related drugs on memory performance in mice. | Physiology & behavior 20040201 |
GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism. | Journal of neurophysiology 20040101 |
The mGlu2/3 receptor agonist, LY354740, blocks immobilization-induced increases in noradrenaline and dopamine release in the rat medial prefrontal cortex. | Journal of neurochemistry 20040101 |
Cannabinoids decrease corticostriatal synaptic transmission via an effect on glutamate uptake. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031203 |
Group II metabotropic glutamate receptor modulation of excitatory transmission in rat subthalamic nucleus. | The Journal of physiology 20031201 |
Protective effect of LY379268, a selective group II metabotropic glutamate receptor agonist, on dizocilpine-induced neuropathological changes in rat retrosplenial cortex. | Brain research 20031128 |
Prefrontal group II metabotropic glutamate receptor activation decreases performance on a working memory task. | Annals of the New York Academy of Sciences 20031101 |
Bidirectional modulation of cystine/glutamate exchanger activity in cultured cortical astrocytes. | Annals of the New York Academy of Sciences 20031101 |
Group II metabotropic glutamate receptor antagonists LY341495 and LY366457 increase locomotor activity in mice. | Neuropharmacology 20031001 |
Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2. | Molecular pharmacology 20031001 |
Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901 |
Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. | Neuropharmacology 20030801 |
Actions of LY341495 on metabotropic glutamate receptor-mediated responses in the neonatal rat spinal cord. | British journal of pharmacology 20030501 |
Reduction of excitatory postsynaptic responses by persistently active metabotropic glutamate receptors in the hippocampus. | Journal of neurophysiology 20030401 |
Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells. | Journal of neurochemistry 20030301 |
Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal neurons of rat sensorimotor cortex. | Journal of neurophysiology 20030301 |
Synthesis and structure-activity relationship studies of novel 2-diarylethyl substituted (2-carboxycycloprop-1-yl)glycines as high-affinity group II metabotropic glutamate receptor ligands. | Bioorganic & medicinal chemistry 20030117 |
Group II metabotropic glutamate receptor modulation of DOI-induced c-fos mRNA and excitatory responses in the cerebral cortex. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101 |
Reduced activity of hippocampal group-I metabotropic glutamate receptors in learning-prone rats. | Neuroscience 20030101 |
Effect of donepezil on group II mGlu receptor agonist- or antagonist-induced amnesia on passive avoidance in mice. | Neural plasticity 20030101 |
Different metabotropic glutamate receptors play opposite roles in synaptic plasticity of the rat medial vestibular nuclei. | The Journal of physiology 20020915 |
Modulation of DOI-induced increases in cortical BDNF expression by group II mGlu receptors. | Pharmacology, biochemistry, and behavior 20020901 |
The anxiolytic action of mGlu2/3 receptor agonist, LY354740, in the fear-potentiated startle model in rats is mechanistically distinct from diazepam. | Pharmacology, biochemistry, and behavior 20020901 |
Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020801 |
Group I metabotropic glutamate receptors (mGluRs) modulate visual responses in the superficial superior colliculus of the rat. | The Journal of physiology 20020615 |
Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3-dependent presynaptic long-term depression at nucleus accumbens synapses. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020601 |
Postsynaptic induction and presynaptic expression of group 1 mGluR-dependent LTD in the hippocampal CA1 region. | Journal of neurophysiology 20020301 |
Neuroprotective effects of N-acetylaspartylglutamate in a neonatal rat model of hypoxia-ischemia. | European journal of pharmacology 20020222 |
Design, synthesis and preliminary evaluation of novel 3'-substituted carboxycyclopropylglycines as antagonists at group 2 metabotropic glutamate receptors. | Bioorganic & medicinal chemistry letters 20011217 |
Internalization of ionotropic glutamate receptors in response to mGluR activation. | Nature neuroscience 20011101 |
Modulation of primary afferent-mediated neurotransmission and Fos expression by glutamate uptake inhibition in rat spinal neurones in vitro. | Neuropharmacology 20011001 |
Differential modulation of the D1-like- and D2-like dopamine receptor-induced locomotor responses by group II metabotropic glutamate receptors in the rat nucleus accumbens. | Neuropharmacology 20010901 |
[3H]LY341495 binding to group II metabotropic glutamate receptors in rat brain. | The Journal of pharmacology and experimental therapeutics 20010801 |
Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists. | Journal of neuroendocrinology 20010801 |
Evidence that glutamate acting on presynaptic type-II metabotropic glutamate receptors alone does not fully account for the phenomenon of depolarisation-induced suppression of inhibition in cerebellar Purkinje cells. | Pflugers Archiv : European journal of physiology 20010601 |
Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata. | Journal of neurophysiology 20010501 |
Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1. | Neuropharmacology 20010101 |
Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes. | Naunyn-Schmiedeberg's archives of pharmacology 20001201 |
Characterization of [(3)H]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using semliki forest virus vectors. | Neuropharmacology 20000724 |
[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells. | Neuropharmacology 19991001 |
Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes. | British journal of pharmacology 19980201 |
LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors. | Neuropharmacology 19980101 |
Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes. | Neuropharmacology 19950801 |