Home Carboxys Zinc, bis(2-pyridinecarboxylato-κN1,κO2)-, (T-4)-

Zinc, bis(2-pyridinecarboxylato-κN1,κO2)-, (T-4)-

CAS No.:
17949-65-4
Catalog Number:
AG002713
Molecular Formula:
C12H8N2O4Zn
Molecular Weight:
309.5829
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$39
- +
5g
98%
In Stock USA
United States
$57
- +
25g
98%
In Stock USA
United States
$94
- +
Product Description
Catalog Number:
AG002713
Chemical Name:
Zinc, bis(2-pyridinecarboxylato-κN1,κO2)-, (T-4)-
CAS Number:
17949-65-4
Molecular Formula:
C12H8N2O4Zn
Molecular Weight:
309.5829
MDL Number:
MFCD00145544
IUPAC Name:
zinc;pyridine-2-carboxylate
InChI:
InChI=1S/2C6H5NO2.Zn/c2*8-6(9)5-3-1-2-4-7-5;/h2*1-4H,(H,8,9);/q;;+2/p-2
InChI Key:
NHVUUBRKFZWXRN-UHFFFAOYSA-L
SMILES:
O=C(c1ccccn1)O[Zn]OC(=O)c1ccccn1
UNII:
ALO92O31SE
Properties
Complexity:
108  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
307.978g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
309.586g/mol
Monoisotopic Mass:
307.978g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
106A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Chromium picolinate attenuates hyperglycemia-induced oxidative stress in streptozotocin-induced diabetic rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20130401
In vitro and in vivo activities of ruthenium(II) phosphine/diimine/picolinate complexes (SCAR) against Mycobacterium tuberculosis. PloS one 20130101
Enhancement of tacrolimus productivity in Streptomyces tsukubaensis by the use of novel precursors for biosynthesis. Enzyme and microbial technology 20121210
The effects of chromium picolinate and chromium histidinate administration on NF-κB and Nrf2/HO-1 pathway in the brain of diabetic rats. Biological trace element research 20121201
Hepatoprotective activity of CrPic against alloxan-induced hepatotoxicity in mice. Biological trace element research 20121101
Lanthanide complexes based on a diazapyridinophane platform containing picolinate pendants. Inorganic chemistry 20121015
Chromium picolinate modulates serotonergic properties and carbohydrate metabolism in a rat model of diabetes. Biological trace element research 20121001
Inhibition of HIV-1 tat-induced transactivation and apoptosis by the divalent metal chelators, fusaric acid and picolinic acid-implications for HIV-1 dementia. Neuroscience research 20120901
Renal and glycemic effects of high-dose chromium picolinate in db/db mice: assessment of DNA damage. The Journal of nutritional biochemistry 20120801
The efficacy of chromium as a growth enhancer for mirror carp (Cyprinus carpio L): an integrated study using biochemical, genetic, and histological responses. Biological trace element research 20120801
A series of three-dimensional architectures constructed from lanthanide-substituted polyoxometalosilicates and lanthanide cations or lanthanide-organic complexes as linkers. Dalton transactions (Cambridge, England : 2003) 20120721
Synthesis and physico-chemical studies of cyclometalated heteroleptic iridium(III) complexes. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120701
[Efficacy of tianmaixiaoke tablets in the treatment of newly diagnosed type 2 diabetes mellitus in China]. Zhonghua yi xue za zhi 20120612
Rapid screening of anabolic steroids in horse urine with ultra-high-performance liquid chromatography/tandem mass spectrometry after chemical derivatisation. Journal of chromatography. A 20120406
Insulin receptors and downstream substrates associate with membrane microdomains after treatment with insulin or chromium(III) picolinate. Cell biochemistry and biophysics 20120401
Elucidating the biosynthetic pathway for the polyketide-nonribosomal peptide collismycin A: mechanism for formation of the 2,2'-bipyridyl ring. Chemistry & biology 20120323
Inhibitory effects of decavanadate on several enzymes and Leishmania tarentolae in vitro. Journal of inorganic biochemistry 20120301
The effect of EDTA, NTA and picolinic acid on Th(IV) mobility in a ternary system with natural sand. Environmental pollution (Barking, Essex : 1987) 20120301
Picolinate ruthenium(II)-arene complex with in vitro antiproliferative and antimetastatic properties: comparison to a series of ruthenium(II)-arene complexes with similar structure. Journal of inorganic biochemistry 20120301
Light-emitting materials from cyclometalated heteroleptic iridium(III) complexes--A physicochemical study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120215
Renal distal tubule proliferation and increased aquaporin 2 level but decreased urine osmolality in db/db mouse: treatment with chromium picolinate. Experimental and molecular pathology 20120201
Ameliorating effect of chromium administration on hepatic glucose metabolism in streptozotocin-induced experimental diabetes. BioFactors (Oxford, England) 20120101
Metabolic stability of new anticonvulsants in body fluids and organ homogenates. Acta poloniae pharmaceutica 20120101
M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection. PloS one 20120101
Picolinic acid in patients with chronic hepatitis C infection: a preliminary report. Mediators of inflammation 20120101
Tuning the reactivity in classic low-spin d6 rhenium(I) tricarbonyl radiopharmaceutical synthon by selective bidentate ligand variation (L,L'-Bid; L,L'= N,N', N,O, and O,O' donor atom sets) in fac-[Re(CO)3(L,L'-Bid)(MeOH)]n complexes. Inorganic chemistry 20111219
Potential of chromium(III) picolinate for reproductive or developmental toxicity following exposure of male CD-1 mice prior to mating. Biological trace element research 20111201
The effect of different levels of organic and inorganic chromium supplementation on production performance, carcass traits and some blood parameters of broiler chicken under heat stress condition. Biological trace element research 20111201
Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats. The FEBS journal 20111101
Effects of chromium picolinate supplementation on the growth, carcass quality and gene expression of beef during the finishing period. Molecular biology reports 20111001
Ruthenium(II) phosphine/diimine/picolinate complexes: inorganic compounds as agents against tuberculosis. European journal of medicinal chemistry 20111001
Fluorescent detection of an anthrax biomarker based on PVA film. The Analyst 20110921
Insulin and chromium picolinate induce translocation of CD36 to the plasma membrane through different signaling pathways in 3T3-L1 adipocytes, and with a differential functionality of the CD36. Biological trace element research 20110901
Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis. Journal of neurochemistry 20110901
Single-molecule magnetic behavior in a neutral terbium(III) complex of a picolinate-based nitronyl nitroxide free radical. Inorganic chemistry 20110815
Chemoselectivity in the Cu-catalyzed O-arylation of phenols and aliphatic alcohols. Chemical communications (Cambridge, England) 20110807
Effect of chromium picolinate supplementation on growth performance and meat characteristics of swine. Biological trace element research 20110601
Alternative and complementary treatments for metabolic syndrome. Current diabetes reports 20110601
Lanthanide dota-like complexes containing a picolinate pendant: structural entry for the design of Ln(III)-based luminescent probes. Inorganic chemistry 20110502
Evidence that chromium modulates cellular cholesterol homeostasis and ABCA1 functionality impaired by hyperinsulinemia--brief report. Arteriosclerosis, thrombosis, and vascular biology 20110501
Performance and ruminal protozoa in lambs with chromium supplementation. Research in veterinary science 20110401
Regulation of organic nucleic acids and serum biochemistry parameters by dietary chromium picolinate supplementation in swine model. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20110401
Complex formation in aqueous solution and in the solid state of the potent insulin-enhancing V(IV)O2+ compounds formed by picolinate and quinolinate derivatives. Inorganic chemistry 20110207
Submandibular gland and caries susceptibility in the obese Zucker rat. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20110201
Mixed ligand cobalt(II) picolinate complexes: synthesis, characterization, DNA binding and photocleavage. Dalton transactions (Cambridge, England : 2003) 20110121
[Synthesis and antituberculosis activity of the derivatives of glycoside steviolbioside from the plant Stevia rebaudiana and diterpenoid isosteviol containing hydrazone, hydrazide and pyridinoyl moieties]. Bioorganicheskaia khimiia 20110101
Exposure to hexavalent chromium resulted in significantly higher tissue chromium burden compared with trivalent chromium following similar oral doses to male F344/N rats and female B6C3F1 mice. Toxicological sciences : an official journal of the Society of Toxicology 20101201
The unexpected role of pyridine-2-carboxylic acid in manganese based oxidation catalysis with pyridin-2-yl based ligands. Dalton transactions (Cambridge, England : 2003) 20101121
Protective role of zinc picolinate on cisplatin-induced nephrotoxicity in rats. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20101101
Effect of dietary chromium picolinate on growth performance and blood parameters in grass carp fingerling, Ctenopharyngodon idellus. Fish physiology and biochemistry 20100901
The kynurenine pathway and inflammation in amyotrophic lateral sclerosis. Neurotoxicity research 20100801
Tissue accumulation and urinary excretion of chromium in rats fed diets containing graded levels of chromium chloride or chromium picolinate. The Journal of toxicological sciences 20100801
The effects of dietary chromium(III) picolinate on growth performance, vital signs, and blood measurements of pigs during immune stress. Biological trace element research 20100601
Improved cognitive-cerebral function in older adults with chromium supplementation. Nutritional neuroscience 20100601
NTP toxicology and carcinogenesis studies of chromium picolinate monohydrate (CAS No. 27882-76-4) in F344/N rats and B6C3F1 mice (feed studies). National Toxicology Program technical report series 20100601
Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus. Metabolism: clinical and experimental 20100501
Enhancement of antibacterial effects of extracts from Cirsium species using sodium picolinate and estimation of their toxicity. Natural product research 20100401
Autoschizis of T-cells is induced by the nutritional supplement, Cr(III)picolinate. Toxicology in vitro : an international journal published in association with BIBRA 20100301
In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial. Current HIV research 20100301
Effects of dietary chromium (III) picolinate on growth performance, respiratory rate, plasma variables, and carcass traits of pigs fed high-fat diets. Biological trace element research 20100201
Effects of chromium(III) picolinate on cortisol and DHEAs secretion in H295R human adrenocortical cells. Biological trace element research 20100201
Ruthenium (II) phosphine/picolinate complexes as antimycobacterial agents. European journal of medicinal chemistry 20100201
Combined effects of one 8-hydroxyquinoline/picolinate and 'CH'/N substitutions on the geometry, electronic structure and optical properties of mer-Alq(3). The journal of physical chemistry. A 20100114
Hypoglycaemia: possible mediation by chromium salt medication. Hormones (Athens, Greece) 20100101
Effects of chromium picolinate on vascular reactivity and cardiac ischemia-reperfusion injury in spontaneously hypertensive rats. Pharmacological reports : PR 20100101
Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK. The Journal of nutritional biochemistry 20091201
Effect of chromium supplementation on the diabetes induced-oxidative stress in liver and brain of adult rats. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20091201
Zinc picolinate in the prevention of leiomyoma in Japanese quail. Journal of medicinal food 20091201
Magneto-structural correlation in a metamagnetic cobalt(II)-based pillared trilayer motif constructed by mixed pyridyl-type carboxylate ligands. Inorganic chemistry 20091102
Development of highly sensitive quantification method for testosterone and dihydrotestosterone in human serum and prostate tissue by liquid chromatography-electrospray ionization tandem mass spectrometry. Steroids 20091101
The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis. The FEBS journal 20091101
Gadolinium(III) complexes of 1,4,7-triazacyclononane based picolinate ligands: simultaneous optimization of water exchange kinetics and electronic relaxation. Dalton transactions (Cambridge, England : 2003) 20091014
Factors that affect oxygen activation and coupling of the two redox cycles in the aromatization reaction catalyzed by NikD, an unusual amino acid oxidase. Biochemistry 20091013
Formation of chiral C(sp3)-C(sp) bond by allylic substitution of secondary allylic picolinates and alkynyl copper reagents. The Journal of organic chemistry 20091002
Anthocyanin production in callus cultures of Cleome rosea: modulation by culture conditions and characterization of pigments by means of HPLC-DAD/ESIMS. Plant physiology and biochemistry : PPB 20091001
Chromium picolinate inhibits resistin secretion in insulin-resistant 3T3-L1 adipocytes via activation of amp-activated protein kinase. Clinical and experimental pharmacology & physiology 20090801
The infrared spectra of Bacillus bacteria part II: sporulated Bacillus--the effect of vegetative cells and contributions of calcium dipicolinate trihydrate, CaDP.3H2O. Applied spectroscopy 20090801
Chromium picolinate induced apoptosis of lymphocytes and the signaling mechanisms thereof. Toxicology and applied pharmacology 20090615
Spectral and kinetic characterization of intermediates in the aromatization reaction catalyzed by NikD, an unusual amino acid oxidase. Biochemistry 20090602
The effects of dietary chromium(III) picolinate on growth performance, blood measurements, and respiratory rate in pigs kept in high and low ambient temperature. Journal of animal science 20090501
Absorption, excretion and retention of 51Cr from labelled Cr-(III)-picolinate in rats. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20090401
Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090401
Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats. European journal of nutrition 20090401
Chromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adults. Metabolic syndrome and related disorders 20090401
Synthesis of the active form of loxoprofen by using allylic substitutions in two steps. Organic letters 20090305
Aerobic degradation of 2-picolinic acid by a nitrobenzene-assimilating strain: Streptomyces sp. Z2. Bioresource technology 20090301
Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid. Journal of neurochemistry 20090301
Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives. Inorganic chemistry 20090216
Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria. International journal for parasitology 20090201
Anti-infectious activity of tryptophan metabolites in the L-tryptophan-L-kynurenine pathway. Biological & pharmaceutical bulletin 20090101
Do dietary supplements help promote weight loss? Journal of dietary supplements 20090101
Use of complexing reagents as additives to the eluent for optimization of separation selectivity in high-performance chelation ion chromatography. Journal of chromatography. A 20081205
Effects of chromium picolinate on oxidative damage in primary piglet hepatocytes. Biological trace element research 20081201
Effects of chromium picolinate on micronucleus frequency and morphology of lymphocytes in calves. Biological trace element research 20081101
Effects of chromium picolinate on food intake and satiety. Diabetes technology & therapeutics 20081001
Highly sensitive analysis of sterol profiles in human serum by LC-ESI-MS/MS. Journal of lipid research 20080901
Lanthanide complexes based on a 1,7-diaza-12-crown-4 platform containing picolinate pendants: a new structural entry for the design of magnetic resonance imaging contrast agents. Inorganic chemistry 20080901
A novel membrane-based anti-diabetic action of atorvastatin. Biochemical and biophysical research communications 20080808
Chromium supplementation improves glucose tolerance in diabetic Goto-Kakizaki rats. IUBMB life 20080801
Development of sensitive derivatization method for aldosterone in liquid chromatography-electrospray ionization tandem mass spectrometry of corticosteroids. Journal of chromatography. A 20080725
Effects of pre- and postnatal exposure to chromium picolinate or picolinic acid on neurological development in CD-1 mice. Biological trace element research 20080701
Antioxidant effect of zinc picolinate in patients with chronic obstructive pulmonary disease. Respiratory medicine 20080601
Preparation and structural elucidation of the picolinyl ester of aldosterone for liquid chromatography-electrospray ionization tandem mass spectrometry. Chemical & pharmaceutical bulletin 20080601
Picolinoxy group, a new leaving group for anti SN2' selective allylic substitution with aryl anions based on Grignard reagents. Organic letters 20080501
Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance. Molecular endocrinology (Baltimore, Md.) 20080401
Chromium picolinate does not produce chromosome damage. Toxicology in vitro : an international journal published in association with BIBRA 20080401
Chromium nanoparticle exhibits higher absorption efficiency than chromium picolinate and chromium chloride in Caco-2 cell monolayers. Journal of animal physiology and animal nutrition 20080401
Crystal structure of Ce(IV)/dipicolinate complex as catalyst for DNA hydrolysis. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080201
Comparison of the potential for developmental toxicity of prenatal exposure to two dietary chromium supplements, chromium picolinate and [Cr3O(O2CCH2CH3)(6(H2O)3]+, in mice. Birth defects research. Part B, Developmental and reproductive toxicology 20080201
Chromium picolinate for insulin resistance in subjects with HIV disease: a pilot study. Diabetes, obesity & metabolism 20080201
Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes. Diabetes/metabolism research and reviews 20080101
Chromium picolinate and conjugated linoleic acid do not synergistically influence diet- and exercise-induced changes in body composition and health indexes in overweight women. The Journal of nutritional biochemistry 20080101
Matrix-assisted laser desorption/ionization signal enhancement of peptides by picolinamidination of amino groups. Rapid communications in mass spectrometry : RCM 20080101
Supplements and the endocrine system in athletes. Clinics in sports medicine 20080101
Study of oxidative damage in growing-finishing pigs with continuous excess dietary chromium picolinate intake. Biological trace element research 20080101
A one-dimensional nickel(II) coordination polymer containing 2,6-dipicolinate and dipyrido[3,2-a:2',3'-c]phenazine. Acta crystallographica. Section C, Crystal structure communications 20071201
Rational selection of the optimum MALDI matrix for top-down proteomics by in-source decay. Analytical chemistry 20071115
Effect of pretreatment with chromium picolinate on haematological parameters during dengue virus infection in mice. The Indian journal of medical research 20071101
Investigating the vanadium environments in hydroxylamido V(V) dipicolinate complexes using 51V NMR spectroscopy and density functional theory. Inorganic chemistry 20071029
So many choices, so what's a consumer to do?: A commentary on 'Effect of chromium niacinate and chromium picolinate supplementation on lipid peroxidation, TNF-alpha, IL-6, CRP, glycated hemoglobin, triglycerides, and cholesterol levels in blood of streptozotocin-treated diabetic rats'. Free radical biology & medicine 20071015
Effect of chromium niacinate and chromium picolinate supplementation on lipid peroxidation, TNF-alpha, IL-6, CRP, glycated hemoglobin, triglycerides, and cholesterol levels in blood of streptozotocin-treated diabetic rats. Free radical biology & medicine 20071015
Influence of dietary L-carnitine and chromium picolinate on blood hormones and metabolites of gestating sows fed one meal per day. Journal of animal science 20071001
Highly sensitive determination of estrone and estradiol in human serum by liquid chromatography-electrospray ionization tandem mass spectrometry. Steroids 20071001
Effect of chronic chromium picolinate in animal models of anxiety and memory. Fundamental & clinical pharmacology 20071001
Monitoring blood glucose levels in female mink during the reproductive cycle: 1. Prevention of hyperglycemia during the nursing period. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20071001
Monitoring blood glucose levels in female mink during the reproductive cycle: 2. Effects of short-term fish oil, chromium picolinate, and acetylsalicylic acid supplementation during late lactation. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20071001
Effect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated rat. Metabolism: clinical and experimental 20070901
A one-dimensional CdII coordination polymer: catena-poly[cadmium(II)-bis(mu-6-methylpicolinato)]. Acta crystallographica. Section C, Crystal structure communications 20070901
4-Carboxyanilinium (2R,3R)-tartrate and a redetermination of the alpha-polymorph of 4-aminobenzoic acid. Acta crystallographica. Section C, Crystal structure communications 20070901
New medications which decrease levothyroxine absorption. Thyroid : official journal of the American Thyroid Association 20070801
Antidiabetic copper(II)-picolinate: impact of the first transition metal in the metallopicolinate complexes. Bioorganic & medicinal chemistry 20070715
Evaluation of the potential genotoxicity of chromium picolinate in mammalian cells in vivo and in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070701
Safety of trivalent chromium complexes: no evidence for DNA damage in human HaCaT keratinocytes. Free radical biology & medicine 20070615
Effects of picolinic acid on the antimicrobial functions of host macrophages against Mycobacterium avium complex. International journal of antimicrobial agents 20070401
Chromium picolinate supplementation in women: effects on body weight, composition, and iron status. Nutrition (Burbank, Los Angeles County, Calif.) 20070301
A pilot study of the safety and efficacy of picolinic acid gel in the treatment of acne vulgaris. The British journal of dermatology 20070301
Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial. The American journal of the medical sciences 20070301
Hypoxia inhibits Moloney murine leukemia virus expression in activated macrophages. Journal of leukocyte biology 20070201
A mobile tryptophan is the intrinsic charge transfer donor in a flavoenzyme essential for nikkomycin antibiotic biosynthesis. Biochemistry 20070123
Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat. Diabetes, obesity & metabolism 20070101
A Dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women. International journal of medical sciences 20070101
Induction of macrophage glutamine: fructose-6-phosphate amidotransferase expression by hypoxia and by picolinic acid. International journal of immunopathology and pharmacology 20070101
Over-the-counter products for weight management. The Alabama nurse 20070101
The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes technology & therapeutics 20061201
Clinical studies on chromium picolinate supplementation in diabetes mellitus--a review. Diabetes technology & therapeutics 20061201
Effects of chromium supplementation on glycogen synthesis after high-intensity exercise. Medicine and science in sports and exercise 20061201
Chromium picolinate positively influences the glucose transporter system via affecting cholesterol homeostasis in adipocytes cultured under hyperglycemic diabetic conditions. Mutation research 20061107
Molecular analysis of hprt mutations induced by chromium picolinate in CHO AA8 cells. Mutation research 20061107
Nutritional supplement chromium picolinate generates chromosomal aberrations and impedes progeny development in Drosophila melanogaster. Mutation research 20061107
Picolinyl ester fragmentation mechanism studies with application to the identification of acylcarnitine acyl groups following transesterification. Journal of the American Society for Mass Spectrometry 20061101
Enhancement of insulin signaling pathway in adipocytes by oxovanadium(IV) complexes. Biochemical and biophysical research communications 20061027
Lack of effect of chromium supplementation on mental state and body weight in people with schizophrenia. Journal of clinical psychopharmacology 20061001
Chromium-picolinate induced ocular changes: Protective role of ascorbic acid. Toxicology 20060921
Activity of picolinic acid in combination with the antiprotozoal drug quinacrine against Mycobacterium avium complex. Antimicrobial agents and chemotherapy 20060901
Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes care 20060801
Chromium picolinate intake and risk of type 2 diabetes: an evidence-based review by the United States Food and Drug Administration. Nutrition reviews 20060801
Chromium picolinate improves insulin sensitivity in obese subjects with polycystic ovary syndrome. Fertility and sterility 20060701
Managing psychiatric disorders with antidiabetic agents: translational research and treatment opportunities. Expert opinion on pharmacotherapy 20060701
Exposure of pregnant mice to chromium picolinate results in skeletal defects in their offspring. Birth defects research. Part B, Developmental and reproductive toxicology 20060601
Experimental (FT-IR, FT-Raman, 1H NMR) and theoretical study of magnesium, calcium, strontium, and barium picolinates. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060501
SanJ, an ATP-dependent picolinate-CoA ligase, catalyzes the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in Streptomyces ansochromogenes. Metabolic engineering 20060501
Separation of nicotinic acid and its structural isomers using 1-ethyl-3-methylimidazolium ionic liquid as a buffer additive by capillary electrophoresis. Journal of pharmaceutical and biomedical analysis 20060411
Chromium activates glucose transporter 4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism. Molecular endocrinology (Baltimore, Md.) 20060401
Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. The Annals of pharmacotherapy 20060301
Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes care 20060301
Chromium picolinate enhances skeletal muscle cellular insulin signaling in vivo in obese, insulin-resistant JCR:LA-cp rats. The Journal of nutrition 20060201
Effect of chromium picolinate on modified forced swimming test in diabetic rats: involvement of serotonergic pathways and potassium channels. Basic & clinical pharmacology & toxicology 20060201
Chromium supplementation. The Medical letter on drugs and therapeutics 20060116
Antimicrobial activity of picolinic acid against extracellular and intracellular Mycobacterium avium complex and its combined activity with clarithromycin, rifampicin and fluoroquinolones. The Journal of antimicrobial chemotherapy 20060101
Vibrational and microbiological study on alkaline metal picolinates and o-iodobenzoates. Analytical and bioanalytical chemistry 20060101
Hypoglycemic potency of novel trivalent chromium in hyperglycemic insulin-deficient rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20060101
[Repercussions of chromium picolinate in the protein metabolism based on the age]. Nutricion hospitalaria 20060101
Design of a hairpin polyamide, ZT65B, for targeting the inverted CCAAT box (ICB) site in the multidrug resistant (MDR1) gene. Chembiochem : a European journal of chemical biology 20051201
Effect of chromium supplementation on insulin resistance and ovarian and menstrual cyclicity in women with polycystic ovary syndrome. Fertility and sterility 20051201
Chromium picolinate does not produce chromosome damage in CHO cells. Mutation research 20051110
Mutagenicity of chromium picolinate and its components in Salmonella typhimurium and L5178Y mouse lymphoma cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20051101
New derivatives of picolinic acid and nicotinic acid with anticonvulsant activity. Protein and peptide letters 20051001
Investigation of novel mediators for a glucose biosensor based on metal picolinate complexes. Bioelectrochemistry (Amsterdam, Netherlands) 20050901
Effects of chronic chromium picolinate treatment in uninephrectomized rat. Metabolism: clinical and experimental 20050901
A double-blind, placebo-controlled, exploratory trial of chromium picolinate in atypical depression: effect on carbohydrate craving. Journal of psychiatric practice 20050901
Characterizing the 'shell phase' formed from amphiphilic picolinates. Journal of the American Chemical Society 20050831
The reaction of [Fe(pic)3] with hydrogen peroxide: a UV-visible and EPR spectroscopic study (Hpic = picolinic acid). Dalton transactions (Cambridge, England : 2003) 20050821
Lack of mutagenicity of chromium picolinate in the hypoxanthine phosphoribosyltransferase gene mutation assay in Chinese hamster ovary cells. Mutation research 20050801
Effects of dietary combination of chromium and biotin on growth performance, carcass characteristics, and oxidative stress markers in heat-distressed Japanese quail. Biological trace element research 20050801
Use of chromium picolinate and biotin in the management of type 2 diabetes: an economic analysis. Disease management : DM 20050801
Effects of dengue virus infection on peripheral blood cells of mice exposed to hexavalent chromium with drinking water. The Indian journal of medical research 20050801
[Adjunctive immunotherapy of mycobacterial infections]. Nihon saikingaku zasshi. Japanese journal of bacteriology 20050801
Chromium picolinate, rather than biotin, alleviates performance and metabolic parameters in heat-stressed quail. British poultry science 20050801
The relationship between chemical structure and antimicrobial activity of selected nicotinates, p-iodobenzoates, picolinates and isonicotinates. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050601
Supplementation of zinc from organic or inorganic source improves performance and antioxidant status of heat-distressed quail. Poultry science 20050601
Chromium supplementation shortens QTc interval duration in patients with type 2 diabetes mellitus. American heart journal 20050401
A validated method for analysis of chromium picolinate in nutraceuticals by reversed phase high performance liquid chromatography. Biomedical chromatography : BMC 20050301
Unusual reactivity in a commercial chromium supplement compared to baseline DNA cleavage with synthetic chromium complexes. Journal of inorganic biochemistry 20050301
Selective allylic hydroxylation of octahydronaphthalene derivatives with a bridgehead double bond using electrochemical method with iron picolinate complexes. Chemical & pharmaceutical bulletin 20050201
Absence of toxic effects in F344/N rats and B6C3F1 mice following subchronic administration of chromium picolinate monohydrate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050101
Chromium picolinate may favorably influence the vascular risk associated with smoking by combating cortisol-induced insulin resistance. Medical hypotheses 20050101
Nonpharmacologic treatments for depression in patients with coronary heart disease. Psychosomatic medicine 20050101
Supplementation with chromium picolinate recovers renal Cr concentration and improves carbohydrate metabolism and renal function in type 2 diabetic mice. Biological trace element research 20050101
[Development research on oxidase functional model iron complexes]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20041201
Initiating insulin in type 2 diabetes. The Israel Medical Association journal : IMAJ 20041201
The central effect of chromium on glucose metabolism. Pharmacopsychiatry 20040901
Resistive training and chromium picolinate: effects on inositols and liver and kidney functions in older adults. International journal of sport nutrition and exercise metabolism 20040801
Influence of Carnichrome on the energy balance of gestating sows. Journal of animal science 20040701
A new electrochemical system for stereoselective allylic hydroxylation of cholesteryl acetate with dioxygen induced by iron picolinate complexes. Chemical & pharmaceutical bulletin 20040601
Augmented inhibition of Candida albicans growth by murine neutrophils in the presence of a tryptophan metabolite, picolinic acid. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20040601
Induction of Mycobacterium avium growth restriction and inhibition of phagosome-endosome interactions during macrophage activation and apoptosis induction by picolinic acid plus IFNgamma. Microbiology (Reading, England) 20040501
Picolinic acid- or desferrioxamine-inducible autocrine activation of macrophages engineered to produce IFNgamma: an approach for gene therapy. Gene therapy 20040301
Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages. Journal of immunology (Baltimore, Md. : 1950) 20040201
Alpha-picolinic acid, a fungal toxin and mammal apoptosis-inducing agent, elicits hypersensitive-like response and enhances disease resistance in rice. Cell research 20040201
Recent advances in the nutritional biochemistry of trivalent chromium. The Proceedings of the Nutrition Society 20040201
Chromium picolinate supplementation improves insulin sensitivity in Goto-Kakizaki diabetic rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20040101
Insulin sensitising action of chromium picolinate in various experimental models of diabetes mellitus. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20040101
Effect of different doses of chromium picolinate on protein metabolism in infant rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20040101
Harnessing chromium in the fight against diabetes. Drug discovery today 20031101
[Chromium (III)-ion enhances the utilization of glucose in type-2 diabetes mellitus]. Orvosi hetilap 20031019
Diuretics vs. ACE inhibitors. The Israel Medical Association journal : IMAJ 20031001
Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. The Journal of infectious diseases 20030915
Effects of treatment with chromium picolinate on peripheral amino acid availability and brain monoamine function in the rat. Pharmacopsychiatry 20030901
Membrane differential filtration is safe and effective for the long-term treatment of Refsum syndrome--an update of treatment modalities and pathophysiological cognition. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20030801
Antifungal activity of macrophages engineered to produce IFNgamma: inducibility by picolinic acid. Medical microbiology and immunology 20030501
Antioxidant properties of chromium and zinc: in vivo effects on digestibility, lipid peroxidation, antioxidant vitamins, and some minerals under a low ambient temperature. Biological trace element research 20030501
Chromium compounds: cytotoxicity and carcinogenesis. Toxicology 20030415
Chromium picolinate for reducing body weight: meta-analysis of randomized trials. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20030401
Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biological psychiatry 20030201
Tissue and subcellular distribution of chromium picolinate with time after entering the bloodstream. Journal of inorganic biochemistry 20030201
The preparation of (S)-aspartate semi-aldehyde appropriate for use in biochemical studies. Bioorganic & medicinal chemistry letters 20030120
The potential value and toxicity of chromium picolinate as a nutritional supplement, weight loss agent and muscle development agent. Sports medicine (Auckland, N.Z.) 20030101
Study of the mechanism of the cytostatic effect of picolinic acid on proliferating Tetrahymena pyriformis cells. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20030101
Effect of chromium picolinate on histopathological alterations in STZ and neonatal STZ diabetic rats. Journal of cellular and molecular medicine 20030101
Macrophage activating properties of the tryptophan catabolite picolinic acid. Advances in experimental medicine and biology 20030101
Antagonistic effect of picolinic acid and interferon-gamma on macrophage inflammatory protein-1alpha/beta production. Cellular immunology 20021101
Ultrastructural damage in chromium picolinate-treated cells: a TEM study. Transmission electron microscopy. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20020901
Drug targeting to the brain: transfer of picolinic acid along the olfactory pathways. Journal of drug targeting 20020901
Structure-dependent metallokinetics of antidiabetic vanadyl-picolinate complexes in rats: studies on solution structure, insulinomimetic activity, and metallokinetics. Journal of inorganic biochemistry 20020725
Flavopiridol inhibits vascular endothelial growth factor production induced by hypoxia or picolinic acid in human neuroblastoma. International journal of cancer 20020610
Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle Glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) rats. The Journal of nutrition 20020601
Effects of resistive training and chromium picolinate on body composition and skeletal muscle size in older women. International journal of sport nutrition and exercise metabolism 20020601
Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body weight in dexamethasone-treated rats. Metabolism: clinical and experimental 20020501
The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria. The Journal of infectious diseases 20020301
A functional food product for the management of weight. Critical reviews in food science and nutrition 20020301
Concurrent quantification of quinolinic, picolinic, and nicotinic acids using electron-capture negative-ion gas chromatography-mass spectrometry. Analytical biochemistry 20020201
In vivo distribution of chromium from chromium picolinate in rats and implications for the safety of the dietary supplement. Chemical research in toxicology 20020201
Effects of dietary chromium picolinate and ascorbic acid supplementation on egg production, egg quality and some serum metabolites of laying hens reared under a low ambient temperature (6 degrees C). Archiv fur Tierernahrung 20020201
Chromium(III) tris(picolinate) is mutagenic at the hypoxanthine (guanine) phosphoribosyltransferase locus in Chinese hamster ovary cells. Mutation research 20020115
The molybdenum-containing xanthine oxidoreductases and picolinate dehydrogenases. Metal ions in biological systems 20020101
Double-blind, placebo-controlled trial of zinc picolinate for taste disorders. Acta oto-laryngologica. Supplementum 20020101
Blood glucose lowering and toxicological effects of zinc (II) complexes with maltol, threonine, and picolinic acid. Research communications in molecular pathology and pharmacology 20020101
Enzyme activities involved in tryptophan metabolism along the kynurenine pathway in rabbits. Biochimica et biophysica acta 20010815
Effect of chromium picolinate and chromium propionate on glucose and insulin kinetics of growing barrows and on growth and carcass traits of growing-finishing barrows. Journal of animal science 20010801
Separation and direct UV detection of lanthanides complexed with pyridine-2-carboxylic acid by capillary electrophoresis. Journal of chromatography. A 20010727
Release of Cr(III) from Cr(III) picolinate upon metabolic activation. Journal of hazardous materials 20010629
Effects of dietary chromium picolinate supplementation on performance and plasma concentrations of insulin and corticosterone in laying hens under low ambient temperature. Journal of animal physiology and animal nutrition 20010601
Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 20010501
The effect of chromium picolinate on muscular strength and body composition in women athletes. Journal of strength and conditioning research 20010501
New high-performance liquid chromatographic method for the detection of picolinic acid in biological fluids. Journal of chromatography. B, Biomedical sciences and applications 20010210
Essential viral and cellular zinc and iron containing metalloproteins as targets for novel antiviral and anticancer agents: implications for prevention and therapy of viral diseases and cancer. Anticancer research 20010101
Oral chromium picolinate and control of glycemia in insulin-treated diabetic dogs. Journal of veterinary internal medicine 20010101
Good news in alternative therapies for diabetes. Pennsylvania medicine 20010101
Antiviral, cytotoxic and apoptotic activities of picolinic acid on human immunodeficiency virus-1 and human herpes simplex virus-2 infected cells. Anticancer research 20010101
Nitric oxide inhibits dioxin action for the stimulation of Cyp1a1 promoter activity. Biological & pharmaceutical bulletin 20000501
Chromium picolinate toxicity. The Annals of pharmacotherapy 19980401
Chromium picolinate modulates rat vascular smooth muscle cell intracellular calcium metabolism. The Journal of nutrition 19980201
Effect of growth hormone or chromium picolinate on swine metabolism and inflammatory cytokine production after endotoxin challenge exposure. American journal of veterinary research 19970601
Effect of recombinant growth hormone and chromium picolinate on cytokine production and growth performance in swine. Pathobiology : journal of immunopathology, molecular and cellular biology 19950101
Protective effect of picolinic acid on mice intracerebrally infected with lethal doses of Candida albicans. Antimicrobial agents and chemotherapy 19931101
Comparative absorption of zinc picolinate, zinc citrate and zinc gluconate in humans. Agents and actions 19870601
Antagonism of kynurenine-induced seizures by picolinic, kynurenic and xanthurenic acids. Journal of neural transmission 19830101
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