Prucalopride succinate
| Title | Journal |
|---|---|
| Pharmacokinetics of single and repeated oral doses prucalopride in healthy Chinese volunteers. | International journal of clinical pharmacology and therapeutics 20121101 |
| Prucalopride: evaluation of the pharmacokinetics, pharmacodynamics, efficacy and safety in the treatment of chronic constipation. | Expert opinion on drug metabolism & toxicology 20121001 |
| The use of Resolor (prucalopride) for chronic constipation in women. | British journal of nursing (Mark Allen Publishing) 20120901 |
| The successful treatment of acute refractory pseudo-obstruction with prucalopride. | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20120801 |
| Recent advances in the management of difficult constipation. | Current gastroenterology reports 20120801 |
| The 5-hydroxytryptamine4 receptor agonists prucalopride and PRX-03140 increase acetylcholine and histamine levels in the rat prefrontal cortex and the power of stimulated hippocampal θ oscillations. | The Journal of pharmacology and experimental therapeutics 20120601 |
| Study of the regulation of the inotropic response to 5-HT4 receptor activation via phosphodiesterases and its cross-talk with C-type natriuretic peptide in porcine left atrium. | Naunyn-Schmiedeberg's archives of pharmacology 20120601 |
| Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae. | Life sciences 20120409 |
| The facilitating effect of prucalopride on cholinergic neurotransmission in pig gastric circular muscle is regulated by phosphodiesterase 4. | Neuropharmacology 20120401 |
| Prucalopride in a case of severe opioid induced constipation. | Minerva anestesiologica 20120401 |
| Assessment of the cardiac safety of prucalopride in healthy volunteers: a randomized, double-blind, placebo- and positive-controlled thorough QT study. | British journal of clinical pharmacology 20120201 |
| Randomised clinical trial: the efficacy of prucalopride in patients with chronic intestinal pseudo-obstruction--a double-blind, placebo-controlled, cross-over, multiple n = 1 study. | Alimentary pharmacology & therapeutics 20120101 |
| In-vitro acetylcholine release is not a straightforward model to study hippocampal 5-HT₄ receptors. | Neuroreport 20111207 |
| Chronic constipation: current treatment options. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20111001 |
| Investigation of neurogenic excitatory and inhibitory motor responses and their control by 5-HT(4) receptors in circular smooth muscle of pig descending colon. | European journal of pharmacology 20110930 |
| Estimating the relationship between preference-based generic utility instruments and disease-specific quality-of-life measures in severe chronic constipation: challenges in practice. | PharmacoEconomics 20110801 |
| [Treatment of severe chronic constipation: differential roles of conventional laxatives and the prucalopride prokinetic]. | Zeitschrift fur Gastroenterologie 20110801 |
| What role for prucalopride in constipation? | Drug and therapeutics bulletin 20110801 |
| Development and validation of a sample stabilization strategy and a UPLC-MS/MS method for the simultaneous quantitation of acetylcholine (ACh), histamine (HA), and its metabolites in rat cerebrospinal fluid (CSF). | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110715 |
| Prucalopride for the treatment of women with chronic constipation in whom standard laxative regimens have failed to provide adequate relief. | Health technology assessment (Winchester, England) 20110501 |
| Prucalopride. In chronic constipation: poorly documented risks. | Prescrire international 20110501 |
| Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis. | Gut 20110201 |
| [New treatment option for women with chronic constipation - prucalopride stimulates the disturbed gut motility again]. | Zeitschrift fur Gastroenterologie 20110101 |
| [Prucalopride - oral (Resolor)]. | Journal de pharmacie de Belgique 20101201 |
| Clinical trial: the efficacy of open-label prucalopride treatment in patients with chronic constipation - follow-up of patients from the pivotal studies. | Alimentary pharmacology & therapeutics 20101101 |
| Efficacy and safety of prucalopride in patients with chronic noncancer pain suffering from opioid-induced constipation. | Digestive diseases and sciences 20101001 |
| A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100901 |
| [New drugs for the treatment of constipation]. | Medizinische Klinik (Munich, Germany : 1983) 20100701 |
| Influence of 5-HT4 receptor activation on acetylcholine release in human large intestine with endometriosis. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100501 |
| Psychometric performance and clinical meaningfulness of the Patient Assessment of Constipation-Quality of Life questionnaire in prucalopride (RESOLOR) trials for chronic constipation. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100201 |
| Prucalopride for constipation. | Expert opinion on pharmacotherapy 20100201 |
| Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat. | PloS one 20100101 |
| Investigations into the binding affinities of different human 5-HT4 receptor splice variants. | Pharmacology 20100101 |
| Safety assessment of prucalopride in elderly patients with constipation: a double-blind, placebo-controlled study. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20091201 |
| Translating 5-HT receptor pharmacology. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20091201 |
| Prucalopride for chronic constipation. | Drugs of today (Barcelona, Spain : 1998) 20091201 |
| Prucalopride: a new drug for the treatment of chronic constipation. | Expert review of gastroenterology & hepatology 20090801 |
| Motility: prucalopride for chronic constipation. | Nature reviews. Gastroenterology & hepatology 20090601 |
| The use of novel promotility and prosecretory agents for the treatment of chronic idiopathic constipation and irritable bowel syndrome with constipation. | Advances in therapy 20090501 |
| Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives. | Gut 20090301 |
| Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation--a 12-week, randomized, double-blind, placebo-controlled study. | Alimentary pharmacology & therapeutics 20090201 |
| Selective desensitization of the 5-HT4 receptor-mediated response in pig atrium but not in stomach. | British journal of pharmacology 20090101 |
| Prucalopride. | Drugs 20090101 |
| New treatments for irritable bowel syndrome in women. | Women's health (London, England) 20081101 |
| Management of constipation in the elderly: emerging therapeutic strategies. | World journal of gastroenterology 20080907 |
| Alternative splicing and exon duplication generates 10 unique porcine 5-HT 4 receptor splice variants including a functional homofusion variant. | Physiological genomics 20080612 |
| A placebo-controlled trial of prucalopride for severe chronic constipation. | The New England journal of medicine 20080529 |
| The long and short of a constipation-reducing medication. | The New England journal of medicine 20080529 |
| Prucalopride and donepezil act synergistically to reverse scopolamine-induced memory deficit in C57Bl/6j mice. | Behavioural brain research 20080305 |
| 5-HT4 receptor agonists increase sAPPalpha levels in the cortex and hippocampus of male C57BL/6j mice. | British journal of pharmacology 20070401 |
| The action of the novel gastrointestinal prokinetic prucalopride on the HERG K+ channel and the common T897 polymorph. | European journal of pharmacology 20070112 |
| 5HT4 agonists inhibit interferon-gamma-induced MHC class II and B7 costimulatory molecules expression on cultured astrocytes. | Journal of neuroimmunology 20061001 |
| 5-HT4 receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20060901 |
| Porcine left atrial and sinoatrial 5-HT(4) receptor-induced responses: fading of the response and influence of development. | British journal of pharmacology 20060101 |
| 5-HT4 receptors located on cholinergic nerves in human colon circular muscle. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20050601 |
| Prucalopride is a partial agonist through human and porcine atrial 5-HT4 receptors: comparison with recombinant human 5-HT4 splice variants. | Naunyn-Schmiedeberg's archives of pharmacology 20050601 |
| Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: viral transfections, subacute and chronic treatments with 5-HT4 agonists. | Biological psychiatry 20050415 |
| Electrophysiological effects of prucalopride, a novel enterokinetic agent, on isolated atrial myocytes from patients treated with beta-adrenoceptor antagonists. | The Journal of pharmacology and experimental therapeutics 20050401 |
| Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease. | Neuroscience 20040101 |
| Effect of enterokinetic prucalopride on intestinal motility in fast rats. | World journal of gastroenterology 20030915 |
| Gastrointestinal motility disorders and gastrointestinal prokinetic therapy. | The Veterinary clinics of North America. Small animal practice 20030901 |
| Irritable bowel syndrome: an overview of diagnosis and pharmacologic treatment. | Cleveland Clinic journal of medicine 20030601 |
| Prucalopride is effective in patients with severe chronic constipation in whom laxatives fail to provide adequate relief. Results of a double-blind, placebo-controlled clinical trial. | Digestion 20030101 |
| 5-HT4 receptors exert a frequency-related facilitatory control on dorsal raphé nucleus 5-HT neuronal activity. | The European journal of neuroscience 20020901 |
| Prucalopride, a systemic enterokinetic, for the treatment of constipation. | Alimentary pharmacology & therapeutics 20020701 |
| Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation. | Alimentary pharmacology & therapeutics 20020401 |
| Efficacy and tolerability of prucalopride in patients with constipation due to spinal cord injury. | Scandinavian journal of gastroenterology 20020401 |
| The effects of the specific 5HT(4) receptor agonist, prucalopride, on colonic motility in healthy volunteers. | Alimentary pharmacology & therapeutics 20020301 |
| Presynaptic modulation of cholinergic neurotransmission in the human proximal stomach. | British journal of pharmacology 20020101 |
| Treatment of GI dysmotility in scleroderma with the new enterokinetic agent prucalopride. | The American journal of gastroenterology 20020101 |
| Pharmacological treatment of irritable bowel syndrome--from concept to sales. | The European journal of surgery. Supplement. : = Acta chirurgica. Supplement 20020101 |
| Serotoninergic neuroenteric modulators. | Lancet (London, England) 20011215 |
| Gastrointestinal prokinetic drugs have different affinity for the human cardiac human ether-à-gogo K(+) channel. | The Journal of pharmacology and experimental therapeutics 20011201 |
| The human serotonin 5-HT4 receptor regulates secretion of non-amyloidogenic precursor protein. | The Journal of biological chemistry 20011130 |
| Effects of the enterokinetic prucalopride (R093877) on colonic motility in fasted dogs. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20011001 |
| Drug therapy options for patients with irritable bowel syndrome. | The American journal of managed care 20010701 |
| The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. | European journal of pharmacology 20010629 |
| 5-HT(4) receptors mediating enhancement of contractility in canine stomach; an in vitro and in vivo study. | British journal of pharmacology 20010401 |
| Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder. | Gastroenterology 20010201 |