Pyrrolidine, 1-[2-(ethenyloxy)-1-oxidodiazenyl]-
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Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450. | Nitric oxide : biology and chemistry 20060601 |
The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen-induced nephrotoxicity in mice. | Toxicology 20030801 |
The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen-induced hepatotoxicity in mice. | Hepatology (Baltimore, Md.) 20030201 |
Plasma pharmacokinetics of a liver-selective nitric oxide-donating diazeniumdiolate in the male C57BL/6 mouse. | Xenobiotica; the fate of foreign compounds in biological systems 20020401 |
O(2)-Vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate protection against D-galactosamine/endotoxin-induced hepatotoxicity in mice: genomic analysis using microarrays. | The Journal of pharmacology and experimental therapeutics 20020101 |
Protection of human keratinocyte mtDNA by low-level nitric oxide. | Nitric oxide : biology and chemistry 20011201 |
V-PYRRO/NO: an hepato-selective nitric oxide donor improves porcine liver hemodynamics and function after ischemia reperfusion. | Transplantation 20010127 |
Nitric oxide prevents tumor necrosis factor alpha-induced rat hepatocyte apoptosis by the interruption of mitochondrial apoptotic signaling through S-nitrosylation of caspase-8. | Hepatology (Baltimore, Md.) 20001001 |
Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver. | Journal of medicinal chemistry 19970620 |