Dl-o-phosphoserine
Title | Journal |
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Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. | Nature 20160121 |
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers. | Nature 20130912 |
The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy. | Genes & development 20130601 |
Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells. | The Journal of biological chemistry 20121214 |
Estrous cycle variations in GABA(A) receptor phosphorylation enable rapid modulation by anabolic androgenic steroids in the medial preoptic area. | Neuroscience 20121213 |
Selective activation of group III metabotropic glutamate receptor subtypes produces different patterns of γ-aminobutyric acid immunoreactivity and glutamate release in the retina. | Journal of neuroscience research 20121201 |
An engineered lantipeptide synthetase serves as a general leader peptide-dependent kinase. | Chemical communications (Cambridge, England) 20121107 |
Differential control of hypoxia-inducible factor 1 activity during pro-inflammatory reactions of human haematopoietic cells of myeloid lineage. | The international journal of biochemistry & cell biology 20121101 |
BRCA1-dependent Chk1 phosphorylation triggers partial chromatin disassociation of phosphorylated Chk1 and facilitates S-phase cell cycle arrest. | The international journal of biochemistry & cell biology 20121101 |
Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3β. | Molecular endocrinology (Baltimore, Md.) 20121101 |
The nuclear localization of glycogen synthase kinase 3β is required its putative PY-nuclear localization sequences. | Molecules and cells 20121031 |
Phenylmethimazole blocks dsRNA-induced IRF3 nuclear translocation and homodimerization. | Molecules (Basel, Switzerland) 20121022 |
Enhanced phosphoserine insertion during Escherichia coli protein synthesis via partial UAG codon reassignment and release factor 1 deletion. | FEBS letters 20121019 |
'In vitro' capacitation and further 'in vitro' progesterone-induced acrosome exocytosis are linked to specific changes in the expression and acrosome location of protein phosphorylation in serine residues of boar spermatozoa. | Reproduction in domestic animals = Zuchthygiene 20121001 |
Key role of integrin α(IIb)β (3) signaling to Syk kinase in tissue factor-induced thrombin generation. | Cellular and molecular life sciences : CMLS 20121001 |
Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance. | Molecular cancer research : MCR 20121001 |
Protein kinase A-mediated phosphorylation of RhoA on serine 188 triggers the rapid induction of a neuroendocrine-like phenotype in prostate cancer epithelial cells. | Cellular signalling 20120801 |
Dehydroepiandrosterone prevents the aggregation of platelets obtained from postmenopausal women with type 2 diabetes mellitus through the activation of the PKC/eNOS/NO pathway. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120701 |
Lipid fingerprinting in women with early-onset preeclampsia: a first look. | Clinical biochemistry 20120701 |
The β-subunit of the SnRK1 complex is phosphorylated by the plant cell death suppressor Adi3. | Plant physiology 20120701 |
Synthesis of a phosphoserine mimetic prodrug with potent 14-3-3 protein inhibitory activity. | Chemistry & biology 20120622 |
Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation. | Journal of cell science 20120601 |
The PDZ-binding motif of MCC is phosphorylated at position -1 and controls lamellipodia formation in colon epithelial cells. | Biochimica et biophysica acta 20120601 |
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. | Autophagy 20120601 |
Evaluation of amino acid O-phosphoserine as ligand for the capture of immunoglubulin G from human serum. | Applied biochemistry and biotechnology 20120601 |
Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo. | Journal of neuroscience research 20120501 |
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. | Open biology 20120501 |
Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. | The Journal of clinical investigation 20120402 |
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. | The Journal of clinical investigation 20120402 |
Unusual fragmentation of Pro-Ser/Thr-containing peptides detected in collision-induced dissociation spectra. | Journal of the American Society for Mass Spectrometry 20120401 |
NF-κB p65 phosphorylated at serine-536 is an independent prognostic factor in Swedish colorectal cancer patients. | International journal of colorectal disease 20120401 |
CDKF;1 and CDKD protein kinases regulate phosphorylation of serine residues in the C-terminal domain of Arabidopsis RNA polymerase II. | The Plant cell 20120401 |
Elk-1 interacts with dynein upon serum stimulation but independent of serine 383 phosphorylation. | Cellular and molecular neurobiology 20120301 |
The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation. | Molecular cancer research : MCR 20120301 |
SPINDLIN1 promotes cancer cell proliferation through activation of WNT/TCF-4 signaling. | Molecular cancer research : MCR 20120301 |
Catalytic mechanism of Sep-tRNA:Cys-tRNA synthase: sulfur transfer is mediated by disulfide and persulfide. | The Journal of biological chemistry 20120217 |
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation. | Human molecular genetics 20120215 |
Plk2 regulates centriole duplication through phosphorylation-mediated degradation of Fbxw7 (human Cdc4). | Journal of cell science 20120215 |
Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function. | Cell death and differentiation 20120201 |
Receptor-mediated modulation of activity-dependent adenosine release in rat cerebellum. | Neuropharmacology 20120201 |
A functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic process. | Cell cycle (Georgetown, Tex.) 20120115 |
Cdc14 phosphatases preferentially dephosphorylate a subset of cyclin-dependent kinase (Cdk) sites containing phosphoserine. | The Journal of biological chemistry 20120113 |
Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression. | Nature 20120109 |
Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines. | The Journal of biological chemistry 20120102 |
Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G. | Journal of leukocyte biology 20120101 |
Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia. | Autophagy 20120101 |
Dichotomy of tyrosine hydroxylase and dopamine regulation between somatodendritic and terminal field areas of nigrostriatal and mesoaccumbens pathways. | PloS one 20120101 |
Dual regulation by ethanol of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats. | Journal of biomedical science 20120101 |
Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase. | PloS one 20120101 |
MGMT inhibition restores ERα functional sensitivity to antiestrogen therapy. | Molecular medicine (Cambridge, Mass.) 20120101 |
Polyphenols sensitization potentiates susceptibility of MCF-7 and MDA MB-231 cells to Centchroman. | PloS one 20120101 |
mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis. | PloS one 20120101 |
Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney development. | PloS one 20120101 |
Improvement of probe peptides for coiled-coil labeling by introducing phosphoserines. | Biopolymers 20120101 |
Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma. | PloS one 20120101 |
Serine-71 phosphorylation of Rac1 modulates downstream signaling. | PloS one 20120101 |
Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms. | PloS one 20120101 |
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+). | Molecular cell 20111223 |
Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling. | Journal of proteome research 20111202 |
High affinity group III mGluRs regulate mossy fiber input to CA3 interneurons. | Hippocampus 20111201 |
Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice. | Molecular psychiatry 20111101 |
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation. | Human molecular genetics 20111101 |
Tomato SlSnRK1 protein interacts with and phosphorylates βC1, a pathogenesis protein encoded by a geminivirus β-satellite. | Plant physiology 20111101 |
Structural and functional assays of AtTLP18.3 identify its novel acid phosphatase activity in thylakoid lumen. | Plant physiology 20111101 |
An optical switch for a motor protein. | Chembiochem : a European journal of chemical biology 20111017 |
Tumor necrosis factor-α activates estrogen signaling pathways in endometrial epithelial cells via estrogen receptor α. | Molecular and cellular endocrinology 20111015 |
Phosphorylation of maize eukaryotic translation initiation factor on Ser2 by catalytic subunit CK2. | Molecular and cellular biochemistry 20111001 |
Induction and activation of the p53 pathway: a role for the protein kinase CK2? | Molecular and cellular biochemistry 20111001 |
Phosphatase and tensin homolog on chromosome 10 is phosphorylated in primary effusion lymphoma and Kaposi's sarcoma. | The American journal of pathology 20111001 |
Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5. | The Journal of biological chemistry 20110923 |
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation. | Nature 20110922 |
EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase. | Journal of cellular physiology 20110901 |
R-Ras interacts with filamin a to maintain endothelial barrier function. | Journal of cellular physiology 20110901 |
Modelling of the gas-phase phosphate group loss and rearrangement in phosphorylated peptides. | Journal of mass spectrometry : JMS 20110901 |
A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes. | Journal of molecular biology 20110826 |
Expanding the genetic code of Escherichia coli with phosphoserine. | Science (New York, N.Y.) 20110826 |
NMR spectroscopy of 14-3-3ζ reveals a flexible C-terminal extension: differentiation of the chaperone and phosphoserine-binding activities of 14-3-3ζ. | The Biochemical journal 20110801 |
Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells. | Endocrinology 20110801 |
Understanding non-enzymatic aminophospholipid glycation and its inhibition. Polar head features affect the kinetics of Schiff base formation. | Bioorganic & medicinal chemistry 20110801 |
Forkhead-associated (FHA) domain containing ABC transporter Rv1747 is positively regulated by Ser/Thr phosphorylation in Mycobacterium tuberculosis. | The Journal of biological chemistry 20110722 |
Tandem mass spectrometric method for definitive localization of phosphorylation sites using bromine signature. | Analytical biochemistry 20110715 |
Nicotinamide attenuates the ischemic brain injury-induced decrease of Akt activation and Bad phosphorylation. | Neuroscience letters 20110708 |
MC3T3-E1 cell differentiation and in vivo bone formation induced by phosphoserine. | Biotechnology letters 20110701 |
Phosphorylation of human calsequestrin: implications for calcium regulation. | Molecular and cellular biochemistry 20110701 |
The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens. | Disease models & mechanisms 20110701 |
Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase is phosphorylated in wheat endosperm at serine-404 by an SNF1-related protein kinase allosterically inhibited by ribose-5-phosphate. | Plant physiology 20110701 |
A Smad action turnover switch operated by WW domain readers of a phosphoserine code. | Genes & development 20110615 |
Light-triggered myosin activation for probing dynamic cellular processes. | Angewandte Chemie (International ed. in English) 20110614 |
GSK-3β: a signaling pathway node modulating neural stem cell and endothelial cell interactions. | Angiogenesis 20110501 |
ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes. | Nature immunology 20110501 |
Metformin induces Rab4 through AMPK and modulates GLUT4 translocation in skeletal muscle cells. | Journal of cellular physiology 20110401 |
Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment. | Biochimica et biophysica acta 20110401 |
OX40 engagement stabilizes Mxd4 and Mnt protein levels in antigen-stimulated T cells leading to an increase in cell survival. | European journal of immunology 20110401 |
Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis. | Oncogene 20110331 |
Fluorescence spectroscopy as a probe of the effect of phosphorylation at serine 40 of tyrosine hydroxylase on the conformation of its regulatory domain. | Biochemistry 20110329 |
INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis. | Cell death and differentiation 20110301 |
A robust protocol to map binding sites of the 14-3-3 interactome: Cdc25C requires phosphorylation of both S216 and S263 to bind 14-3-3. | Molecular & cellular proteomics : MCP 20110301 |
IKKε regulates cell elongation through recycling endosome shuttling. | Developmental cell 20110215 |
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. | Nature 20110203 |
mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn. | Burns : journal of the International Society for Burn Injuries 20110201 |
Functionalized graphene oxide as a nanocarrier in a multienzyme labeling amplification strategy for ultrasensitive electrochemical immunoassay of phosphorylated p53 (S392). | Analytical chemistry 20110201 |
Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant. | Anesthesiology 20110201 |
Regulation of yeast Yak1 kinase by PKA and autophosphorylation-dependent 14-3-3 binding. | Molecular microbiology 20110201 |
Ferric ions inhibit proteolytic processing of progastrin. | Biochemical and biophysical research communications 20110128 |
Phosphoserine-modified calcium phosphate cements: bioresorption and substitution. | Journal of tissue engineering and regenerative medicine 20110101 |
Light-induced phosphorylation of crystallins in the retinal pigment epithelium. | International journal of biological macromolecules 20110101 |
Issues associated with the use of phosphospecific antibodies to localise active and inactive pools of GSK-3 in cells. | Biology direct 20110101 |
Evolutionary patterns of phosphorylated serines. | Biology direct 20110101 |
Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease. | PloS one 20110101 |
Role of p53 serine 46 in p53 target gene regulation. | PloS one 20110101 |
The serine 814 of TRPC6 is phosphorylated under unstimulated conditions. | PloS one 20110101 |
Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-α. | PloS one 20110101 |
Prognostic association of YB-1 expression in breast cancers: a matter of antibody. | PloS one 20110101 |
Detailed regulatory mechanism of the interaction between ZO-1 PDZ2 and connexin43 revealed by MD simulations. | PloS one 20110101 |
Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF. | PloS one 20110101 |
Phosphorylation provides a negative mode of regulation for the yeast Rab GTPase Sec4p. | PloS one 20110101 |
Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells. | PloS one 20110101 |
The multi-level action of fatty acids on adiponectin production by fat cells. | PloS one 20110101 |
XPA-mediated regulation of global nucleotide excision repair by ATR Is p53-dependent and occurs primarily in S-phase. | PloS one 20110101 |
Differential phosphorylation of ribosomal proteins in Arabidopsis thaliana plants during day and night. | PloS one 20110101 |
Nitric oxide, erythrocytes and exercise. | Clinical hemorheology and microcirculation 20110101 |
p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition. | Journal of cell science 20101215 |
Positional effects of phosphoserine on β-hairpin stability. | Organic & biomolecular chemistry 20101207 |
Functional relevance of the IRF-1 promoter polymorphism rs2549009 on transcriptional activity in a native genomic environment. | Human molecular genetics 20101201 |
Uncovering new substrates for Aurora A kinase. | EMBO reports 20101201 |
In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation. | Biophysical journal 20101201 |
Inhibition of constitutive activation of STAT3 by curcurbitacin-I (JSI-124) sensitized human B-leukemia cells to apoptosis. | Molecular cancer therapeutics 20101201 |
mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α. | Molecular cell 20101124 |
DDK phosphorylates checkpoint clamp component Rad9 and promotes its release from damaged chromatin. | Molecular cell 20101124 |
Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations. | Experimental cell research 20101115 |
CdSe/ZnS quantum dots based electrochemical immunoassay for the detection of phosphorylated bovine serum albumin. | Biosensors & bioelectronics 20101115 |
Crosstalk between mRNA 3' end processing and transcription initiation. | Molecular cell 20101112 |
Phosphorylated and nonphosphorylated serine and threonine residues evolve at different rates in mammals. | Molecular biology and evolution 20101101 |
The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina. | Experimental eye research 20101101 |
Activation of Atg1 kinase in autophagy by regulated phosphorylation. | Autophagy 20101101 |
Degree of immobilization of synthetic RGDS(PO(3)H(2))PA peptides on titanium surfaces. | Dental materials journal 20101101 |
Determination of L-serine-O-phosphate in rat and mouse brain tissue using high-performance liquid chromatography and fluorimetric detection. | Analytical biochemistry 20101015 |
Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle. | The Biochemical journal 20101015 |
Role of ligand-dependent GR phosphorylation and half-life in determination of ligand-specific transcriptional activity. | Molecular and cellular endocrinology 20101007 |
Uniform transitions of the general RNA polymerase II transcription complex. | Nature structural & molecular biology 20101001 |
Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. | Nature structural & molecular biology 20101001 |
Gene-specific RNA polymerase II phosphorylation and the CTD code. | Nature structural & molecular biology 20101001 |
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. | Nature 20100916 |
Focus on histone variant H2AX: to be or not to be. | FEBS letters 20100910 |
AMPK regulates metabolic actions of glucocorticoids by phosphorylating the glucocorticoid receptor through p38 MAPK. | Molecular endocrinology (Baltimore, Md.) 20100901 |
Chk1-dependent constitutive phosphorylation of BLM helicase at serine 646 decreases after DNA damage. | Molecular cancer research : MCR 20100901 |
Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. | PLoS genetics 20100901 |
The Kunitz-3 domain of TFPI-alpha is required for protein S-dependent enhancement of factor Xa inhibition. | Blood 20100826 |
Group III metabotropic glutamate receptors inhibit startle-mediating giant neurons in the caudal pontine reticular nucleus but do not mediate synaptic depression/short-term habituation of startle. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100804 |
Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors. | Science translational medicine 20100804 |
Potentiation of etoposide-induced apoptosis in HeLa cells by co-treatment with KG-135, a quality-controlled standardized ginsenoside formulation. | Cancer letters 20100801 |
Overexpression of alpha-synuclein down-regulates BDNF expression. | Cellular and molecular neurobiology 20100801 |
Cell death of prostate cancer cells by specific amino acid restriction depends on alterations of glucose metabolism. | Journal of cellular physiology 20100801 |
Tau Ser262 phosphorylation is critical for Abeta42-induced tau toxicity in a transgenic Drosophila model of Alzheimer's disease. | Human molecular genetics 20100801 |
The effect of spermine concentration on the solution structure of complexes formed in copper(II)/adenosine 5'-triphosphate/phosphoserine system. | Journal of inorganic biochemistry 20100801 |
Kidney-induced hypertension depends on superoxide signaling in the rostral ventrolateral medulla. | Hypertension (Dallas, Tex. : 1979) 20100801 |
Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease. | British journal of pharmacology 20100801 |
Mitotic Golgi vesiculation involves mechanisms independent of Ser25 phosphorylation of GM130. | Cell cycle (Georgetown, Tex.) 20100801 |
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. | Nature 20100722 |
Liaisons between survivin and Plk1 during cell division and cell death. | The Journal of biological chemistry 20100716 |
Dueling post-translational modifications trigger folding and unfolding of a beta-hairpin peptide. | Journal of the American Chemical Society 20100707 |
CK2 phosphorylates TNFAIP1 to affect its subcellular localization and interaction with PCNA. | Molecular biology reports 20100701 |
Identification of androgen receptor phosphorylation in the primate ovary in vivo. | Reproduction (Cambridge, England) 20100701 |
Channel-like crystal structure of cinchoninium L-O-phosphoserine salt dihydrate. | Chirality 20100601 |
Reciprocal epigenetic modification of histone H2B occurs in chromatin during apoptosis in vitro and in vivo. | Cell death and differentiation 20100601 |
Quantitative measurement of in vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE. | Molecular & cellular proteomics : MCP 20100601 |
Stt7-dependent phosphorylation during state transitions in the green alga Chlamydomonas reinhardtii. | Molecular & cellular proteomics : MCP 20100601 |
AMP-activated protein kinase inhibits IGF-I signaling and protein synthesis in vascular smooth muscle cells via stimulation of insulin receptor substrate 1 S794 and tuberous sclerosis 2 S1345 phosphorylation. | Molecular endocrinology (Baltimore, Md.) 20100601 |
Autophagy regulates keratin 8 homeostasis in mammary epithelial cells and in breast tumors. | Molecular cancer research : MCR 20100601 |
Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis. | The FEBS journal 20100601 |
Identification of a small molecule inhibitor of serine 276 phosphorylation of the p65 subunit of NF-kappaB using in silico molecular docking. | Cancer letters 20100528 |
Role of CK1 in GSK3beta-mediated phosphorylation and degradation of snail. | Oncogene 20100527 |
A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration. | Human molecular genetics 20100515 |
Ponsin interacts with Nck adapter proteins: implications for a role in cytoskeletal remodelling during differentiation of skeletal muscle cells. | European journal of cell biology 20100501 |
CDK5 phosphorylates eNOS at Ser-113 and regulates NO production. | Journal of cellular biochemistry 20100501 |
ATM is involved in cell-cycle control through the regulation of retinoblastoma protein phosphorylation. | Journal of cellular biochemistry 20100501 |
Conformational preferences and prolyl cis-trans isomerization of phosphorylated Ser/Thr-Pro motifs. | Biopolymers 20100401 |
Protein phosphatase 1alpha associates with protein tyrosine phosphatase-PEST inducing dephosphorylation of phospho-serine 39. | Journal of biochemistry 20100401 |
Screening kinase inhibitors with a microarray-based fluorescent and resonance light scattering assay. | Analytical chemistry 20100401 |
Dual regulation of a Dictyostelium STAT by cGMP and Ca2+ signalling. | Journal of cell science 20100315 |
TACC3-TSC2 maintains nuclear envelope structure and controls cell division. | Cell cycle (Georgetown, Tex.) 20100315 |
Sex differences in estrogen receptor subcellular location and activity in lung adenocarcinoma cells. | American journal of respiratory cell and molecular biology 20100301 |
ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration. | Carcinogenesis 20100301 |
Interleukin-1 Receptor-Associated Kinase-1 (IRAK-1) functionally associates with PKCepsilon and VASP in the regulation of macrophage migration. | Molecular immunology 20100301 |
(15)N Solid-state NMR spectroscopic studies on phospholamban at its phosphorylated form at ser-16 in aligned phospholipid bilayers. | Biochimica et biophysica acta 20100301 |
Laminar shear stress modulates phosphorylation and localization of RNA polymerase II on the endothelial nitric oxide synthase gene. | Arteriosclerosis, thrombosis, and vascular biology 20100301 |
Short communication: ischemia/reperfusion tolerance is time-of-day-dependent: mediation by the cardiomyocyte circadian clock. | Circulation research 20100219 |
Is there a better time of day to have a heart attack? | Circulation research 20100219 |
Inhibitory role of cAMP on doxorubicin-induced apoptosis in pre-B ALL cells through dephosphorylation of p53 serine residues. | Apoptosis : an international journal on programmed cell death 20100201 |
Glucuronic acid and phosphoserine act as mineralization mediators of collagen I based biomimetic substrates. | Journal of materials science. Materials in medicine 20100201 |
Regulation of heat shock protein 60 and 72 expression in the failing heart. | Journal of molecular and cellular cardiology 20100201 |
GGA autoinhibition revisited. | Traffic (Copenhagen, Denmark) 20100201 |
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. | Developmental biology 20100115 |
Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity. | Journal of cell science 20100115 |
Selective control of gene expression by CDK9 in human cells. | Journal of cellular physiology 20100101 |
Suppression of DNA-PKcs enhances FGF-2 dependent human endothelial cell proliferation via negative regulation of Akt. | Cellular signalling 20100101 |
VASP phosphorylation at serine239 regulates the effects of NO on smooth muscle cell invasion and contraction of collagen. | Journal of cellular physiology 20100101 |
Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. | The Journal of biological chemistry 20100101 |
HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2. | The Journal of biological chemistry 20100101 |
Src kinase-mediated phosphorylation stabilizes inducible nitric-oxide synthase in normal cells and cancer cells. | The Journal of biological chemistry 20100101 |
Serine-threonine kinase receptor-associated protein inhibits apoptosis signal-regulating kinase 1 function through direct interaction. | The Journal of biological chemistry 20100101 |
Shear stress stimulates nitric oxide signaling in pulmonary arterial endothelial cells via a reduction in catalase activity: role of protein kinase C delta. | American journal of physiology. Lung cellular and molecular physiology 20100101 |
Cell lines derived from a medaka radiation-sensitive mutant have defects in DNA double-strand break responses. | Journal of radiation research 20100101 |
The masticatory contractile load induced expression and activation of Akt1/PKBalpha in muscle fibers at the myotendinous junction within muscle-tendon-bone unit. | Journal of biomedicine & biotechnology 20100101 |
Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain. | Molecular pain 20100101 |
Basal endothelial nitric oxide synthase (eNOS) phosphorylation on Ser(1177) occurs in a stable microtubule- and tubulin acetylation-dependent manner. | Experimental cell research 20091210 |
Convergent evolution of coenzyme M biosynthesis in the Methanosarcinales: cysteate synthase evolved from an ancestral threonine synthase. | The Biochemical journal 20091210 |
Dissection of Rad9 BRCT domain function in the mitotic checkpoint response to telomere uncapping. | DNA repair 20091203 |
Site-specifically phosphorylated forms of H1.5 and H1.2 localized at distinct regions of the nucleus are related to different processes during the cell cycle. | Chromosoma 20091201 |
L-Serine-O-phosphate in the central nervous system. | Brain research 20091201 |
Focus on phosphoarginine and phospholysine. | Current protein & peptide science 20091201 |
Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis. | Nature cell biology 20091201 |
Ultraviolet photodissociation at 266 nm of phosphorylated peptide cations. | Rapid communications in mass spectrometry : RCM 20091201 |
Urgent termination of pregnancy in pre-eclampsia and panel of antiphospholipid antibodies. | American journal of reproductive immunology (New York, N.Y. : 1989) 20091201 |
Potentiation of spinal NMDA-mediated nociception by cocaine- and amphetamine-regulated transcript peptide via PKA and PKC signaling pathways in rats. | Regulatory peptides 20091127 |
Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. | Blood 20091126 |
EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin. | Molecular cell 20091125 |
Analysis of phosphorylated peptides by double pseudoneutral loss extraction coupled with derivatization using N-(4-bromobenzoyl)aminoethanethiol. | Analytical chemistry 20091115 |
Phosphorylation at S384 regulates the activity of the TaALMT1 malate transporter that underlies aluminum resistance in wheat. | The Plant journal : for cell and molecular biology 20091101 |
Intermedin/adrenomedullin-2 is a hypoxia-induced endothelial peptide that stabilizes pulmonary microvascular permeability. | American journal of physiology. Lung cellular and molecular physiology 20091101 |
The role of phosphorylated glucocorticoid receptor in mitochondrial functions and apoptotic signalling in brain tissue of stressed Wistar rats. | The international journal of biochemistry & cell biology 20091101 |
Basal autophagy induction without AMP-activated protein kinase under low glucose conditions. | Autophagy 20091101 |
The regulation mechanism for the auto-inhibition of binding of human filamin A to integrin. | Journal of molecular biology 20091030 |
The Ess1 prolyl isomerase is required for transcription termination of small noncoding RNAs via the Nrd1 pathway. | Molecular cell 20091023 |
Phosphorylation of phospholipase C-delta 1 regulates its enzymatic activity. | Journal of cellular biochemistry 20091015 |
Developmental switch in NF-kappaB signalling required for neurite growth. | Development (Cambridge, England) 20091015 |
Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan. | Journal of the American Chemical Society 20091007 |
Protein phosphorylation influences proteolytic cleavage and kinase substrate properties exemplified by analysis of in vitro phosphorylated Plasmodium falciparum glideosome-associated protein 45 by nano-ultra performance liquid chromatography-tandem mass spectrometry. | Analytical biochemistry 20091001 |
Enhancing the apoptotic potential of insulin-like growth factor-binding protein-3 in prostate cancer by modulation of CK2 phosphorylation. | Molecular endocrinology (Baltimore, Md.) 20091001 |
Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin-1. | Diabetes 20091001 |
The trafficking/interaction of eNOS and caveolin-1 induced by insulin modulates endothelial nitric oxide production. | Molecular endocrinology (Baltimore, Md.) 20091001 |
DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20091001 |
The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat. | Behavioural pharmacology 20091001 |
Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages. | Journal of proteome research 20091001 |
Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats. | British journal of pharmacology 20091001 |
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. | Molecular cancer therapeutics 20091001 |
The alpha,alpha-difluorinated phosphonate L-pSer-analogue: an accessible chemical tool for studying kinase-dependent signal transduction. | Chemistry & biology 20090925 |
Journal club. A biologist is gratified to find reconciliation for a conflicted receptor. | Nature 20090910 |
CDK11p58 phosphorylation of PAK1 Ser174 promotes DLC2 binding and roles on cell cycle progression. | Journal of biochemistry 20090901 |
Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041. | Molecular & cellular proteomics : MCP 20090901 |
SADB phosphorylation of gamma-tubulin regulates centrosome duplication. | Nature cell biology 20090901 |
Recognition of an intra-chain tandem 14-3-3 binding site within PKCepsilon. | EMBO reports 20090901 |
SAD kinase keeps centrosomes lonely. | Nature cell biology 20090901 |
Phosphorylation of CLASP2 by GSK-3beta regulates its interaction with IQGAP1, EB1 and microtubules. | Journal of cell science 20090815 |
Parathyroid hormone suppresses insulin signaling in adipocytes. | Molecular and cellular endocrinology 20090813 |
Morphine induces DNA damage and P53 activation in CD3+ T cells. | Biochimica et biophysica acta 20090801 |
Caenorhabditis elegans has a phosphoproteome atypical for metazoans that is enriched in developmental and sex determination proteins. | Journal of proteome research 20090801 |
Activation of mTORC1 signaling pathway in AIDS-related lymphomas. | The American journal of pathology 20090801 |
Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. | The Journal of biological chemistry 20090731 |
Protein kinase C isoforms differentially phosphorylate Ca(v)1.2 alpha(1c). | Biochemistry 20090721 |
The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation. | Science (New York, N.Y.) 20090717 |
EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt. | Cancer cell 20090707 |
IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation. | American journal of physiology. Lung cellular and molecular physiology 20090701 |
Phosphoproteomic analysis of the human pathogen Trypanosoma cruzi at the epimastigote stage. | Proteomics 20090701 |
KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells. | Blood 20090625 |
Opposite effects of PDGF-BB and prostaglandin E1 on cell-motility related processes are paralleled by modifications of distinct actin-binding proteins. | Experimental cell research 20090610 |
mTOR mediates human trophoblast invasion through regulation of matrix-remodeling enzymes and is associated with serine phosphorylation of STAT3. | Experimental cell research 20090610 |
Regulation of microtubule dynamic instability in vitro by differentially phosphorylated stathmin. | The Journal of biological chemistry 20090605 |
Cyclic GMP specifically suppresses Type-Ialpha cGMP-dependent protein kinase expression by ubiquitination. | Cellular signalling 20090601 |
TLR4/MyD88/PI3K interactions regulate TLR4 signaling. | Journal of leukocyte biology 20090601 |
Discovery and identification of serine and threonine phosphorylated proteins in activated mast cells: implications for regulation of protein synthesis in the rat basophilic leukemia mast cell line RBL-2H3. | Journal of proteome research 20090601 |
Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein. | Human mutation 20090601 |
Phosphorylation-dependent binding of human transcription factor MOK2 to lamin A/C. | The FEBS journal 20090601 |
PP2A antagonizes phosphorylation of Bazooka by PAR-1 to control apical-basal polarity in dividing embryonic neuroblasts. | Developmental cell 20090601 |
p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling. | The Journal of biological chemistry 20090529 |
Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR. | The Journal of biological chemistry 20090529 |
Structure and in vivo requirement of the yeast Spt6 SH2 domain. | Journal of molecular biology 20090529 |
Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK. | The Journal of biological chemistry 20090522 |
Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation. | The Journal of biological chemistry 20090522 |
Activation-induced degradation of FLIP(L) is mediated via the phosphatidylinositol 3-kinase/Akt signaling pathway in macrophages. | The Journal of biological chemistry 20090522 |
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. | Nature 20090521 |
In silico analysis of phosphoproteome data suggests a rich-get-richer process of phosphosite accumulation over evolution. | Molecular & cellular proteomics : MCP 20090501 |
14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival. | The Journal of biological chemistry 20090501 |
Phosphoserine and specific types of its coordination in copper(II) and adenosine nucleotides systems - Potentiometric and spectroscopic studies. | Journal of inorganic biochemistry 20090501 |
Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells. | Diabetologia 20090501 |
Identification of casein kinase-1 phosphorylation sites on TDP-43. | Biochemical and biophysical research communications 20090501 |
Oncostatin M-induced CCL2 transcription in osteoblastic cells is mediated by multiple levels of STAT-1 and STAT-3 signaling: an implication for the pathogenesis of arthritis. | Arthritis and rheumatism 20090501 |
RNF2 is the target for phosphorylation by the p38 MAPK and ERK signaling pathways. | Proteomics 20090501 |
EBAG9 inducing hyporesponsiveness of T cells promotes tumor growth and metastasis in 4T1 murine mammary carcinoma. | Cancer science 20090501 |
Galpha(q)-mediated plasma membrane translocation of sphingosine kinase-1 and cross-activation of S1P receptors. | Biochimica et biophysica acta 20090501 |
Probing the mechanism of electron capture and electron transfer dissociation using tags with variable electron affinity. | Journal of the American Chemical Society 20090422 |
Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis. | The Journal of biological chemistry 20090403 |
Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest. | The Journal of biological chemistry 20090403 |
Ran GTPase guanine nucleotide exchange factor RCC1 is phosphorylated on serine 11 by cdc2 kinase in vitro. | Molecular biology reports 20090401 |
Identification and characterization of neuronal mitogen-activated protein kinase substrates using a specific phosphomotif antibody. | Molecular & cellular proteomics : MCP 20090401 |
Sulfonation and phosphorylation of regions of the dioxin receptor susceptible to methionine modifications. | Molecular & cellular proteomics : MCP 20090401 |
Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. | Nature cell biology 20090401 |
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. | Nature cell biology 20090401 |
Distinct role of PLCbeta3 in VEGF-mediated directional migration and vascular sprouting. | Journal of cell science 20090401 |
Skp2: caught in the Akt. | Nature cell biology 20090401 |
Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells. | Developmental cell 20090401 |
Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190. | BMB reports 20090331 |
[Preparation and preliminary application of rabbit polyclonal antibodies against intracellular peptides of human platelet glycoprotein GPIbalpha]. | Zhonghua yi xue za zhi 20090331 |
Role of p53 in mitochondrial biogenesis and apoptosis in skeletal muscle. | Physiological genomics 20090303 |
Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites. | Molecular & cellular proteomics : MCP 20090301 |
TTP at Ser245 phosphorylation by AKT is required for binding to 14-3-3. | Journal of biochemistry 20090301 |
[Development of a functional cell-based HTS assay for the identification mGluR4 modulators]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090301 |
The effect of post-translational and process-induced modifications on the multistage gas-phase fragmentation reactions of protonated peptides. | Combinatorial chemistry & high throughput screening 20090201 |
Bone morphogenic protein 2 activates protein kinase D to regulate histone deacetylase 7 localization and repression of Runx2. | The Journal of biological chemistry 20090123 |
Protein kinase D1 autophosphorylation via distinct mechanisms at Ser744/Ser748 and Ser916. | The Journal of biological chemistry 20090123 |
Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance. | The Journal of biological chemistry 20090123 |
Inhibition of lactoperoxidase by its own catalytic product: crystal structure of the hypothiocyanate-inhibited bovine lactoperoxidase at 2.3-A resolution. | Biophysical journal 20090121 |
Cell cycle regulation of the BRCA1/acetyl-CoA-carboxylase complex. | Biochemical and biophysical research communications 20090116 |
Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression. | Molecular cell 20090116 |
Clinical and pathological characteristics of patients with leucine-rich repeat kinase-2 mutations. | Movement disorders : official journal of the Movement Disorder Society 20090115 |
The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms. | Experimental cell research 20090115 |
The stability and transactivation potential of the mammalian MafA transcription factor are regulated by serine 65 phosphorylation. | The Journal of biological chemistry 20090109 |
Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells. | Circulation research 20090102 |
Tissue-specific difference in the molecular mechanisms for the development of acute insulin resistance after injury. | Endocrinology 20090101 |
PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway. | Experimental cell research 20090101 |
Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc. | Experimental cell research 20090101 |
Detection and assignment of phosphoserine and phosphothreonine residues by (13)C- (31)P spin-echo difference NMR spectroscopy. | Journal of biomolecular NMR 20090101 |
PP2A regulates ionizing radiation-induced apoptosis through Ser46 phosphorylation of p53. | Molecular cancer therapeutics 20090101 |
Transient dynamic actin cytoskeletal change stimulates the osteoblastic differentiation. | Journal of bone and mineral metabolism 20090101 |
Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. | PloS one 20090101 |
Systematic functional analysis of Bicaudal-D serine phosphorylation and intragenic suppression of a female sterile allele of BicD. | PloS one 20090101 |
Detection of histone H3 phosphorylation in cultured cells and tissue sections by immunostaining. | Methods in molecular biology (Clifton, N.J.) 20090101 |
Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins. | Methods in enzymology 20090101 |
Nicotine-reduced endothelial progenitor cell senescence through augmentation of telomerase activity via the PI3K/Akt pathway. | Cytotherapy 20090101 |
Protein phosphorylation by semisynthesis: from paper to practice. | Methods in enzymology 20090101 |
Glutamatergic neurotransmission in the first retinal synapse mediated by metabotropic receptors--electroretinographic study. | Folia medica 20090101 |
Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease. | Molecular brain 20090101 |
Phosphorylation regulates human T-cell leukemia virus type 1 Rex function. | Retrovirology 20090101 |
The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function. | PloS one 20090101 |
Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factors. | PloS one 20090101 |
Aging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation. | PloS one 20090101 |
Induction of serum- and glucocorticoid-induced kinase-1 (SGK1) by cAMP regulates increases in alpha-ENaC. | Journal of cellular physiology 20081201 |
Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. | Journal of cellular physiology 20081201 |
BMP-2 increases migration of human chondrosarcoma cells via PI3K/Akt pathway. | Journal of cellular physiology 20081201 |
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. | Cell death and differentiation 20081201 |
Estrogen receptor alpha (ERalpha) phospho-serine-118 is highly expressed in human uterine leiomyomas compared to matched myometrium. | Virchows Archiv : an international journal of pathology 20081201 |
Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily. | The FEBS journal 20081201 |
Magnetic electrochemical immunoassays with quantum dot labels for detection of phosphorylated acetylcholinesterase in plasma. | Analytical chemistry 20081115 |
Characterization of Ser338 phosphorylation for Raf-1 activation. | The Journal of biological chemistry 20081114 |
Integrin cross-talk in endothelial cells is regulated by protein kinase A and protein phosphatase 1. | The Journal of biological chemistry 20081114 |
Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes. | Biochemical and biophysical research communications 20081107 |
Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression. | Oncogene 20081106 |
O-phospho-L-serine and the thiocarboxylated sulfur carrier protein CysO-COSH are substrates for CysM, a cysteine synthase from Mycobacterium tuberculosis. | Biochemistry 20081104 |
Mass spectrometry analysis of oxidized phospholipids. | Chemistry and physics of lipids 20081101 |
JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin. | Cellular signalling 20081101 |
Preservation of cGMP-induced relaxation of pulmonary veins of fetal lambs exposed to chronic high altitude hypoxia: role of PKG and Rho kinase. | American journal of physiology. Lung cellular and molecular physiology 20081101 |
Hyaluronan-mediated leukocyte adhesion and dextran sulfate sodium-induced colitis are attenuated in the absence of signal transducer and activator of transcription 1. | The American journal of pathology 20081101 |
MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation. | Development (Cambridge, England) 20081101 |
Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism. | Hepatology (Baltimore, Md.) 20081101 |
P53 transcription-independent activity mediates selenite-induced acute promyelocytic leukemia NB4 cell apoptosis. | BMB reports 20081031 |
Temperature sensitivity of phospho-Ser(473)-PKB/AKT. | Biochemical and biophysical research communications 20081024 |
Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells. | Chemico-biological interactions 20081022 |
CDK targets Sae2 to control DNA-end resection and homologous recombination. | Nature 20081002 |
Unraveling molecular complexity of phosphorylated human cardiac troponin I by top down electron capture dissociation/electron transfer dissociation mass spectrometry. | Molecular & cellular proteomics : MCP 20081001 |
WNK2 modulates MEK1 activity through the Rho GTPase pathway. | Cellular signalling 20081001 |
Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites. | Cellular signalling 20081001 |
Cdk5 phosphorylates PLD2 to mediate EGF-dependent insulin secretion. | Cellular signalling 20081001 |
DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks. | DNA repair 20081001 |
The role of phosphorylated residues in peptide-peptide noncovalent complexes formation. | Journal of the American Society for Mass Spectrometry 20081001 |
Cyclophosphoramidate ion as mass defect marker for efficient detection of protein serine phosphorylation. | Analytical chemistry 20081001 |
O-phospho-L-serine: a modulator of bone healing in calcium-phosphate cements. | Biomedizinische Technik. Biomedical engineering 20081001 |
Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts. | Molecular cancer therapeutics 20081001 |
[The preparation of bioglass/collagen/phosphoserine biomemetic composite scaffold and a study on its cytocompatibility]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20081001 |
Identification and characterization of a general nuclear translocation signal in signaling proteins. | Molecular cell 20080926 |
Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. | Molecular cell 20080926 |
CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation. | Molecular cell 20080926 |
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37. | Molecular cell 20080926 |
RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning. | Proceedings of the National Academy of Sciences of the United States of America 20080923 |
ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage. | Cell cycle (Georgetown, Tex.) 20080915 |
p21 activated kinase 5 activates Raf-1 and targets it to mitochondria. | Journal of cellular biochemistry 20080901 |
Phosphorylation and kinetics of mammalian cytochrome c oxidase. | Molecular & cellular proteomics : MCP 20080901 |
Evaluating CK2 activity with the antibody specific for the CK2-phosphorylated form of a kinase-targeting cochaperone Cdc37. | Molecular and cellular biochemistry 20080901 |
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia. | Molecular pharmacology 20080901 |
RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in Drosophila. | Development (Cambridge, England) 20080901 |
Involvement of the p53 and p73 transcription factors in neuroAIDS. | Cell cycle (Georgetown, Tex.) 20080901 |
Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS. | FEBS letters 20080820 |
Resveratrol causes COX-2- and p53-dependent apoptosis in head and neck squamous cell cancer cells. | Journal of cellular biochemistry 20080815 |
Array-based fluorescence assay for serine/threonine kinases using specific chemical reaction. | Bioorganic & medicinal chemistry 20080815 |
Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei. | The Journal of biological chemistry 20080808 |
The homotetrameric phosphoseryl-tRNA synthetase from Methanosarcina mazei exhibits half-of-the-sites activity. | The Journal of biological chemistry 20080808 |
TGF-beta inhibits prolactin-induced expression of beta-casein by a Smad3-dependent mechanism. | Journal of cellular biochemistry 20080801 |
Importance of autophosphorylation at Ser186 in the A-loop of salt inducible kinase 1 for its sustained kinase activity. | Journal of cellular biochemistry 20080801 |
Glucocorticoid receptor phosphorylation differentially affects target gene expression. | Molecular endocrinology (Baltimore, Md.) 20080801 |
Phosphoserine aminoacylation of tRNA bearing an unnatural base anticodon. | Biochemical and biophysical research communications 20080801 |
The Arabidopsis thaliana carboxyl-terminal domain phosphatase-like 2 regulates plant growth, stress and auxin responses. | Plant molecular biology 20080801 |
Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8. | The Journal of biological chemistry 20080718 |
Reactive nitrogen species is required for the activation of the AMP-activated protein kinase by statin in vivo. | The Journal of biological chemistry 20080718 |
Polymerized collagen inhibits fibroblast proliferation via a mechanism involving the formation of a beta1 integrin-protein phosphatase 2A-tuberous sclerosis complex 2 complex that suppresses S6K1 activity. | The Journal of biological chemistry 20080718 |
Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells. | Journal of cell science 20080715 |
A wide-ranging cellular response to UV damage of DNA. | Cell cycle (Georgetown, Tex.) 20080715 |
Phosphorylation of protein phosphatase 2Czeta by c-Jun NH2-terminal kinase at Ser92 attenuates its phosphatase activity. | Biochemistry 20080708 |
The cell cycle control protein cdc25C is present, and phosphorylated on serine 214 in the transition from germinal vesicle to metaphase II in human oocyte meiosis. | Molecular reproduction and development 20080701 |
Structural consequences of phosphorylation of two serine residues in the cytoplasmic domain of HIV-1 VpU. | Journal of peptide science : an official publication of the European Peptide Society 20080701 |
Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation. | Diabetes 20080701 |
Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria. | Cellular signalling 20080701 |
Anti-apoptotic action of Wnt5a in dermal fibroblasts is mediated by the PKA signaling pathways. | Cellular signalling 20080701 |
Oxidative stress and calpain inhibition induce alpha B-crystallin phosphorylation via p38-MAPK and calcium signalling pathways in H9c2 cells. | Cellular signalling 20080701 |
G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFkappaB serine 536 phosphorylation in human keratinocytes. | Cellular signalling 20080701 |
The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells. | American journal of physiology. Renal physiology 20080701 |
Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase. | Cellular signalling 20080701 |
Akt stabilizes estrogen receptor alpha with the concomitant reduction in its transcriptional activity. | Cellular signalling 20080701 |
MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling. | Journal of immunology (Baltimore, Md. : 1950) 20080701 |
Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia. | Journal of immunology (Baltimore, Md. : 1950) 20080701 |
A phosphatase cascade by which rewarding stimuli control nucleosomal response. | Nature 20080612 |
GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis. | Journal of cellular physiology 20080601 |
Polo-box domains confer target specificity to the Polo-like kinase family. | Biochimica et biophysica acta 20080601 |
The PIP2 binding mode of the C2 domains of rabphilin-3A. | Protein science : a publication of the Protein Society 20080601 |
Role of the C-terminal domain of RNA polymerase II in expression of small nuclear RNA genes. | Biochemical Society transactions 20080601 |
Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer. | Molecular cancer therapeutics 20080601 |
Phosphorylation of delta2 glutamate receptors at serine 945 is not required for cerebellar long-term depression. | The Keio journal of medicine 20080601 |
Proton chemical shift anisotropy measurements of hydrogen-bonded functional groups by fast magic-angle spinning solid-state NMR spectroscopy. | Chemical communications (Cambridge, England) 20080528 |
Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis. | The Journal of biological chemistry 20080523 |
Sequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylation. | The Journal of biological chemistry 20080509 |
A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression. | The Journal of biological chemistry 20080509 |
TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation. | Journal of molecular biology 20080509 |
Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. | The Journal of biological chemistry 20080502 |
The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5. | The Biochemical journal 20080501 |
Abrogation of hyperosmotic impairment of insulin signaling by a novel class of 1,2-dithiole-3-thiones through the inhibition of S6K1 activation. | Molecular pharmacology 20080501 |
Aminoacylation of tRNA with phosphoserine for synthesis of cysteinyl-tRNA(Cys). | Nature structural & molecular biology 20080501 |
Embryonically expressed GABA and glutamate drive electrical activity regulating neurotransmitter specification. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080430 |
The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily. | The Biochemical journal 20080415 |
Calcineurin-mediated dephosphorylation of c-Jun Ser-243 is required for c-Jun protein stability and cell transformation. | Oncogene 20080410 |
Differential regulation of IKK alpha-mediated activation of IRF3/7 by NIK. | Molecular immunology 20080401 |
cPLA2 phosphorylation at serine-515 and serine-505 is required for arachidonic acid release in vascular smooth muscle cells. | Journal of lipid research 20080401 |
Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages. | Molecular and cellular biology 20080401 |
Role of vasodilator-stimulated phosphoprotein in cGMP-mediated protection of human pulmonary artery endothelial barrier function. | American journal of physiology. Lung cellular and molecular physiology 20080401 |
The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain. | The FEBS journal 20080401 |
Selective roles of MAPKs during the macrophage response to IFN-gamma. | Journal of immunology (Baltimore, Md. : 1950) 20080401 |
Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis. | Journal of immunology (Baltimore, Md. : 1950) 20080401 |
14-3-3 Proteins directly regulate Ca(2+)/calmodulin-dependent protein kinase kinase alpha through phosphorylation-dependent multisite binding. | FEBS letters 20080305 |
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues. | FEBS letters 20080305 |
Gymnemic acid interacts with mammalian glycerol-3-phosphate dehydrogenase. | Molecular and cellular biochemistry 20080301 |
Nuclear localization signal and phosphorylation of Serine350 specify intracellular localization of DRAK2. | Journal of biochemistry 20080301 |
The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats. | Neuropharmacology 20080301 |
Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients. | Diabetologia 20080301 |
Phosphorylation mediates Sp1 coupled activities of proteolytic processing, desumoylation and degradation. | Cell cycle (Georgetown, Tex.) 20080301 |
Analysis of the cell adhesion molecule sticks-and-stones reveals multiple redundant functional domains, protein-interaction motifs and phosphorylated tyrosines that direct myoblast fusion in Drosophila melanogaster. | Genetics 20080301 |
Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells. | Cell cycle (Georgetown, Tex.) 20080301 |
In situ observation of protein phosphorylation by high-resolution NMR spectroscopy. | Nature structural & molecular biology 20080301 |
Identification of p32 as a novel substrate for ATM in heart. | Biochemical and biophysical research communications 20080222 |
Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo. | Circulation 20080219 |
Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells. | Circulation 20080219 |
Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells. | Nature 20080207 |
Group III metabotropic glutamate receptors act as hetero-receptors modulating evoked GABA release in the globus pallidus in vivo. | European journal of pharmacology 20080202 |
PKD, PKD2, and p38 MAPK mediate Hsp27 serine-82 phosphorylation induced by neurotensin in pancreatic cancer PANC-1 cells. | Journal of cellular biochemistry 20080201 |
MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080201 |
Cyclin-dependent kinase phosphorylation of RUNX1/AML1 on 3 sites increases transactivation potency and stimulates cell proliferation. | Blood 20080201 |
Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes. | Journal of molecular and cellular cardiology 20080201 |
A sulfated, phosphorylated 7 kDa secreted peptide characterized by direct analysis of cell culture media. | Journal of proteome research 20080201 |
Mechanistic insights into the multistage gas-phase fragmentation behavior of phosphoserine- and phosphothreonine-containing peptides. | Journal of proteome research 20080201 |
Disruption of PDGFRalpha-initiated PI3K activation and migration of somite derivatives leads to spina bifida. | Development (Cambridge, England) 20080201 |
Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in Drosophila. | Development (Cambridge, England) 20080201 |
Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation. | Nature medicine 20080201 |
Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma. | International journal of molecular medicine 20080201 |
Dual role of proapoptotic BAD in insulin secretion and beta cell survival. | Nature medicine 20080201 |
Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals. | Molecular cell 20080118 |
Phosphorylation-dependent binding of cyclin B1 to a Cdc6-like domain of human separase. | The Journal of biological chemistry 20080111 |
Fibrous and helical calcite crystals induced by synthetic polypeptides containing o-phospho-L-serine and o-phospho-L-threonine. | Macromolecular bioscience 20080109 |
Cadmium induces mitochondria-dependent apoptosis of normal human hepatocytes. | Cell biology and toxicology 20080101 |
DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity. | Biochimica et biophysica acta 20080101 |
Amyloid beta-peptide 31-35-induced neuronal apoptosis is mediated by caspase-dependent pathways via cAMP-dependent protein kinase A activation. | Aging cell 20080101 |
GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers. | Cancer cell 20080101 |
Inhibition of transcription by the Caenorhabditis elegans germline protein PIE-1: genetic evidence for distinct mechanisms targeting initiation and elongation. | Genetics 20080101 |
The transactivation domain of heterogeneous nuclear ribonucleoprotein K overlaps its nuclear shuttling domain. | The international journal of biochemistry & cell biology 20080101 |
Decorin derived antiangiogenic peptide LRR5 inhibits endothelial cell migration by interfering with VEGF-stimulated NO release. | The international journal of biochemistry & cell biology 20080101 |
Large-scale phosphorylation mapping reveals the extent of tyrosine phosphorylation in Arabidopsis. | Molecular systems biology 20080101 |
PKC putative phosphorylation site Ser235 is required for MIP/AQP0 translocation to the plasma membrane. | Molecular vision 20080101 |
Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1. | BMC molecular biology 20080101 |
Shark skeletal muscle tropomyosin is a phosphoprotein. | Journal of muscle research and cell motility 20080101 |
Phosphorylation sites on Tyr28 and the C-terminus of Rad9 are required for inhibition of premature chromosomal condensation across the entire S phase. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1. | Breast cancer research : BCR 20080101 |
Serine phosphorylation-dependent coregulation of topoisomerase I by the p14ARF tumor suppressor. | Biochemistry 20071211 |
Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases. | Proceedings of the National Academy of Sciences of the United States of America 20071211 |
The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules. | Experimental cell research 20071210 |
The tolerance property of human D3 dopamine receptor is determined by specific amino acid residues in the second cytoplasmic loop. | Biochimica et biophysica acta 20071201 |
Acinus-provoked protein kinase C delta isoform activation is essential for apoptotic chromatin condensation. | Cell death and differentiation 20071201 |
Transcriptional regulation of the androgen receptor cofactor androgen receptor trapped clone-27. | Molecular endocrinology (Baltimore, Md.) 20071201 |
Calcitonin targets extracellular signal-regulated kinase signaling pathway in human cancers. | Journal of molecular endocrinology 20071201 |
Phosphorylation-regulated cleavage of the reticulon protein Nogo-B by caspase-7 at a noncanonical recognition site. | Proteomics 20071201 |
[Expression and significance of Ser10 phosphorylated p27(kip1) and JAB1 protein in human hepatocellular carcinoma]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20071201 |
GSK-3-mediated phosphorylation enhances Maf-transforming activity. | Molecular cell 20071130 |
Phosphopeptide elution times in reversed-phase liquid chromatography. | Journal of chromatography. A 20071116 |
The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways. | International journal of cancer 20071115 |
Enhancement by lithium of cAMP-induced CRE/CREB-directed gene transcription conferred by TORC on the CREB basic leucine zipper domain. | The Biochemical journal 20071115 |
Identification of Tim4 as a phosphatidylserine receptor. | Nature 20071115 |
Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin. | Cellular signalling 20071101 |
Proteomic approach for caudal trauma-induced acute phase proteins reveals that creatine kinase is a key acute phase protein in amphioxus humoral fluid. | Journal of proteome research 20071101 |
Regulation of cell cycle progression and gene expression by H2A deubiquitination. | Nature 20071025 |
Replication stress, defective S-phase checkpoint and increased death in Plk2-deficient human cancer cells. | Cell cycle (Georgetown, Tex.) 20071015 |
Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies. | FEBS letters 20071002 |
[The spliceosome and its interest for lupus therapy]. | La Revue de medecine interne 20071001 |
Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells. | Experimental cell research 20071001 |
17Beta-oestradiol partially attenuates the inhibition of nitric oxide synthase-3 by advanced glycation end-products in human platelets. | Clinical and experimental pharmacology & physiology 20071001 |
14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase. | Experimental cell research 20071001 |
Histone deacetylase 1 phosphorylation at S421 and S423 is constitutive in vivo, but dispensable in vitro. | Biochemical and biophysical research communications 20070921 |
Rho-kinase phosphorylates eNOS at threonine 495 in endothelial cells. | Biochemical and biophysical research communications 20070921 |
DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118. | Oncogene 20070906 |
One-trial in vitro conditioning of hermissenda regulates phosphorylation of ser-122 of csp24. | Annals of the New York Academy of Sciences 20070901 |
Phosphorylation and ubiquitination are necessary for Na,K-ATPase endocytosis during hypoxia. | Cellular signalling 20070901 |
Opposing effects of Bad phosphorylation at two distinct sites by Akt1 and JNK1/2 on ischemic brain injury. | Cellular signalling 20070901 |
Phosphorylation at Ser729 specifies a Golgi localisation for protein kinase C epsilon (PKCepsilon) in 3T3 fibroblasts. | Cellular signalling 20070901 |
A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation. | Chemistry & biology 20070901 |
Phosphorylation at carboxyl-terminal S373 and S375 residues and 14-3-3 binding are not required for mouse p53 function. | Neoplasia (New York, N.Y.) 20070901 |
Positive regulation of deoxycytidine kinase activity by phosphorylation of Ser-74 in B-cell chronic lymphocytic leukaemia lymphocytes. | Cancer letters 20070808 |
ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate. | Biochemical and biophysical research communications 20070803 |
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. | Diabetes 20070801 |
Impulse-driven heated-droplet deposition interface for capillary and microbore LC-MALDI MS and MS/MS. | Analytical chemistry 20070801 |
Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage. | Nucleic acids research 20070801 |
Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein. | Molecular cancer therapeutics 20070801 |
Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology. | The Journal of biological chemistry 20070727 |
Novel phosphorylation site markers of protein kinase C delta activation. | FEBS letters 20070724 |
Differential effects of phosphorylation on DNA binding properties of N Oct-3 are dictated by protein/DNA complex structures. | Journal of molecular biology 20070720 |
Increased phosphorylation of p70 S6 kinase is associated with HPV16 infection in cervical cancer and esophageal cancer. | British journal of cancer 20070716 |
Phosphomimetic mutation of the mitotically phosphorylated serine 1880 compromises the interaction of the transmembrane nucleoporin gp210 with the nuclear pore complex. | Experimental cell research 20070715 |
Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53. | The EMBO journal 20070711 |
SIRT1 regulates the function of the Nijmegen breakage syndrome protein. | Molecular cell 20070706 |
TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway. | Cellular signalling 20070701 |
Ginkgo biloba extract EGb 761 increases endothelial nitric oxide production in vitro and in vivo. | Cellular and molecular life sciences : CMLS 20070701 |
Improving fragmentation of poorly fragmenting peptides and phosphopeptides during collision-induced dissociation by malondialdehyde modification of arginine residues. | Journal of mass spectrometry : JMS 20070701 |
Mass spectrometric studies on mouse hippocampal synapsins Ia, IIa, and IIb and identification of a novel phosphorylation site at serine-546. | Journal of proteome research 20070701 |
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator. | Nature 20070621 |
PKCepsilon increases phosphorylation of the cardiac myosin binding protein C at serine 302 both in vitro and in vivo. | Biochemistry 20070612 |
The effect of intrahippocampal injection of group II and III metobotropic glutamate receptor agonists on anxiety; the role of neuropeptide Y. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070601 |
Loss of heterozygosity of the p53 gene and deregulated expression of its mRNA and protein in human brain tumors. | Molecular and cellular biochemistry 20070601 |
Ankyrin repeat and SOCS box containing protein 4 (Asb-4) interacts with GPS1 (CSN1) and inhibits c-Jun NH2-terminal kinase activity. | Cellular signalling 20070601 |
Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle. | Diabetes 20070601 |
FcepsilonRI and Thy-1 domains have unique protein and lipid compositions. | Journal of lipid research 20070601 |
Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication. | Nature immunology 20070601 |
Pin1 in neuronal apoptosis. | Cell cycle (Georgetown, Tex.) 20070601 |
O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII. | The AAPS journal 20070601 |
A multiplexed protein kinase assay. | Chembiochem : a European journal of chemical biology 20070525 |
Identification of a molecular target for the Yersinia protein kinase A. | Molecular cell 20070525 |
C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A. | Cell death and differentiation 20070501 |
C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB. | Immunity 20070501 |
Arabidopsis protein kinase PKS5 inhibits the plasma membrane H+ -ATPase by preventing interaction with 14-3-3 protein. | The Plant cell 20070501 |
Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif. | Experimental & molecular medicine 20070430 |
A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs. | Nature 20070426 |
Mitosis-specific MPM-2 phosphorylation of DNA topoisomerase IIalpha is regulated directly by protein phosphatase 2A. | The Biochemical journal 20070415 |
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity. | The Journal of biological chemistry 20070413 |
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. | The Journal of biological chemistry 20070413 |
CMTM8 induces caspase-dependent and -independent apoptosis through a mitochondria-mediated pathway. | Journal of cellular physiology 20070401 |
Structural determinants of LL5beta subcellular localisation and association with filamin C. | Cellular signalling 20070401 |
Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid. | Journal of cellular physiology 20070401 |
Effect of modification of hydroxyapatite/collagen composites with sodium citrate, phosphoserine, phosphoserine/RGD-peptide and calcium carbonate on bone remodelling. | Bone 20070401 |
CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways. | Biochimica et biophysica acta 20070401 |
Activation of caspase 3 in HepG2 cells by elaidic acid (t18:1). | Biochimica et biophysica acta 20070401 |
Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea. | Nature structural & molecular biology 20070401 |
Two waves of the nuclear phospholipase C activity in serum-stimulated HL-60 cells during G(1) phase of the cell cycle. | Biochimica et biophysica acta 20070401 |
Phosphotyrosine/phosphoserine binary switches: a new paradigm for the regulation of PI3K signalling and growth factor pleiotropy? | Biochemical Society transactions 20070401 |
Luteolin sensitizes the anticancer effect of cisplatin via c-Jun NH2-terminal kinase-mediated p53 phosphorylation and stabilization. | Molecular cancer therapeutics 20070401 |
Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS. | The Biochemical journal 20070315 |
DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. | Molecular cell 20070309 |
MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis. | Molecular cell 20070309 |
Glycogen synthase kinase-3beta binds to E2F1 and regulates its transcriptional activity. | Biochimica et biophysica acta 20070301 |
Acute impairment of insulin signalling by dexamethasone in primary cultured rat skeletal myocytes. | Molecular and cellular biochemistry 20070301 |
Approach to systematic analysis of serine/threonine phosphoproteome using Beta elimination and subsequent side effects: intramolecular linkage and/or racemisation. | Journal of cellular biochemistry 20070301 |
Effect of HPr phosphorylation on structure, dynamics, and interactions in the course of transcriptional control. | Journal of molecular modeling 20070301 |
Temporal dissociation of frequency-dependent acceleration of relaxation and protein phosphorylation by CaMKII. | Journal of molecular and cellular cardiology 20070301 |
Protein kinase C inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma protein. | Biochimica et biophysica acta 20070301 |
[Shigella flexneri modulates host cell epigenetic information as a strategy to shape the transcriptional response]. | Medecine sciences : M/S 20070301 |
Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators. | The Journal of steroid biochemistry and molecular biology 20070301 |
Evidence for the location of the allosteric activation switch in the multisubunit phosphorylase kinase complex from mass spectrometric identification of chemically crosslinked peptides. | Journal of molecular biology 20070202 |
Cdk5 regulates STAT3 activation and cell proliferation in medullary thyroid carcinoma cells. | The Journal of biological chemistry 20070202 |
p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis. | Cell death and differentiation 20070201 |
Mobile phone base station-emitted radiation does not induce phosphorylation of Hsp27. | Bioelectromagnetics 20070201 |
c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells. | American journal of physiology. Lung cellular and molecular physiology 20070201 |
Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice. | Neuropharmacology 20070201 |
[VE-cadherin takes a walk on the wild side]. | Medecine sciences : M/S 20070201 |
Synthesis, platelet adhesion and cytotoxicity studies of new glycerophosphoryl-containing polyurethanes. | The International journal of artificial organs 20070201 |
Lithium regulates glycogen synthase kinase-3beta in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorder. | Biological psychiatry 20070115 |
Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells. | Journal of immunology (Baltimore, Md. : 1950) 20070115 |
The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. | Genes & development 20070115 |
Gcn5 promotes acetylation, eviction, and methylation of nucleosomes in transcribed coding regions. | Molecular cell 20070112 |
Involvement of PKCalpha in insulin-induced PKCdelta expression: Importance of SP-1 and NFkappaB transcription factors. | Biochemical and biophysical research communications 20070105 |
The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas. | Molecular and cellular biochemistry 20070101 |
Immunoassay of serine-phosphorylated isoform of insulin-like growth factor (IGF) binding protein (IGFBP)-1. | Clinical biochemistry 20070101 |
Selective activation of group III metabotropic glutamate receptors by L-(+)-2-amino-4-phosphonobutryic acid protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo. | The Journal of pharmacology and experimental therapeutics 20070101 |
Characterization of beta2-adrenergic receptor dephosphorylation: Comparison with the rate of resensitization. | Molecular pharmacology 20070101 |
Raf kinase inhibitor protein affects activity of Plasmodium falciparum calcium-dependent protein kinase 1. | Molecular and biochemical parasitology 20070101 |
A sharper instrument for dissecting signalling events: a specific AGC kinase inhibitor. | The Biochemical journal 20070101 |
Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress. | The Journal of cell biology 20070101 |
Biosynthesis of selenocysteine on its tRNA in eukaryotes. | PLoS biology 20070101 |
Stress-associated MAP kinase fills in the map of filamin-mediated neuronal migration. | Developmental cell 20070101 |
Analysis of mitotic phosphorylation of borealin. | BMC cell biology 20070101 |
p42MAPK-mediated phosphorylation of xEIAP/XLX in Xenopus cytostatic factor-arrested egg extracts. | BMC biochemistry 20070101 |
Involvement of glycogen synthase kinase-3beta in palmitate-induced human umbilical vein endothelial cell apoptosis. | Journal of vascular research 20070101 |
ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke. | BMC cell biology 20070101 |
UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity. | Journal of molecular microbiology and biotechnology 20070101 |
ODF1 phosphorylation by Cdk5/p35 enhances ODF1-OIP1 interaction. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101 |
CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72. | PloS one 20070101 |
Phosphorylated GSK3beta-ser9 and EGFR are good prognostic factors for lung carcinomas. | Anticancer research 20070101 |
KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions. | Cancer research 20061215 |
Asbestos redirects nitric oxide signaling through rapid catalytic conversion to nitrite. | Cancer research 20061215 |
ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling. | The EMBO journal 20061213 |
Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation. | The EMBO journal 20061213 |
Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesis. | Oncogene 20061207 |
Differential effects of systemic ethanol administration on protein kinase cepsilon, gamma, and beta isoform expression, membrane translocation, and target phosphorylation: reversal by chronic ethanol exposure. | The Journal of pharmacology and experimental therapeutics 20061201 |
Post-translational control of Nur77. | Biochemical Society transactions 20061201 |
Protein phosphatases types 2Calpha and 2Cbeta in apoptosis. | Biochemical Society transactions 20061201 |
Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence. | Cell cycle (Georgetown, Tex.) 20061201 |
TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner. | Cell cycle (Georgetown, Tex.) 20061201 |
Human Cdc14A reverses CDK1 phosphorylation of Cdc25A on serines 115 and 320. | Cell cycle (Georgetown, Tex.) 20061201 |
Critical role of vimentin phosphorylation at Ser-56 by p21-activated kinase in vimentin cytoskeleton signaling. | The Journal of biological chemistry 20061110 |
Signaling pathways regulating murine cardiac CREB phosphorylation. | Biochemical and biophysical research communications 20061110 |
The NR4A orphan nuclear receptor NOR1 is induced by platelet-derived growth factor and mediates vascular smooth muscle cell proliferation. | The Journal of biological chemistry 20061103 |
Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha. | The Journal of biological chemistry 20061103 |
Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation. | The Journal of biological chemistry 20061103 |
Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-kappaB transactivation by RANKL. | Cell death and differentiation 20061101 |
Ser58 of mouse p53 is the homologue of human Ser46 and is phosphorylated by HIPK2 in apoptosis. | Cell death and differentiation 20061101 |
Modulation of ceramide metabolism enhances viral protein apoptin's cytotoxicity in prostate cancer. | Molecular therapy : the journal of the American Society of Gene Therapy 20061101 |
Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. | Journal of pineal research 20061101 |
PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function. | Biochemical and biophysical research communications 20061027 |
Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells. | FEBS letters 20061016 |
Glucagon-mediated internalization of serine-phosphorylated glucagon receptor and Gsalpha in rat liver. | FEBS letters 20061016 |
CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage. | Science (New York, N.Y.) 20061013 |
Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling. | Oncogene 20061012 |
PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K. | Cellular signalling 20061001 |
AKT can be activated in the nucleus. | Cellular signalling 20061001 |
Hypertonicity activates GSK3beta in tumor cells. | Molecular and cellular biochemistry 20061001 |
Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress. | Diabetologia 20061001 |
Supercell and subcell description of the crystal structure of triammonium bis(O-phospho-L-serinate) trihydrate. | Acta crystallographica. Section B, Structural science 20061001 |
Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo. | Nature 20060914 |
Regulation of connexin-43-mediated growth inhibition by a phosphorylatable amino-acid is independent of gap junction-forming ability. | Molecular and cellular biochemistry 20060901 |
Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine. | The Journal of biological chemistry 20060901 |
Context-dependent regulation of embryonic stem cell differentiation by mGlu4 metabotropic glutamate receptors. | Neuropharmacology 20060901 |
Ethanol inhibition of NMDA-induced responses and acute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases. | Neuropharmacology 20060901 |
Mutations of phosphorylation sites Ser10 and Thr187 of p27Kip1 abolish cytoplasmic redistribution but do not abrogate G0/1 phase arrest in the HepG2 cell line. | Biochemical and biophysical research communications 20060901 |
The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1. | Genes to cells : devoted to molecular & cellular mechanisms 20060901 |
Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta. | Molecular cell 20060901 |
Wip1 phosphatase modulates ATM-dependent signaling pathways. | Molecular cell 20060901 |
Phosphorylation of ERalpha at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ERalpha phosphorylation in breast cancer progression. | Endocrine-related cancer 20060901 |
Histone phosphorylation and pericentromeric histone modifications in oocyte meiosis. | Cell cycle (Georgetown, Tex.) 20060901 |
Learning induces long-term potentiation in the hippocampus. | Science (New York, N.Y.) 20060825 |
ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage. | Science (New York, N.Y.) 20060825 |
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation. | Science (New York, N.Y.) 20060818 |
Single crystals of L-O-serine phosphate X-irradiated at low temperatures: EPR, ENDOR, EIE, and DFT studies. | The journal of physical chemistry. A 20060810 |
Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells. | Biochemical and biophysical research communications 20060804 |
Neighbored phosphorylation sites as PHF-tau specific markers in Alzheimer's disease. | Biochemical and biophysical research communications 20060804 |
beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870. | Cellular signalling 20060801 |
Activation of Group II/III metabotropic glutamate receptors attenuates LPS-induced astroglial neurotoxicity via promoting glutamate uptake. | Journal of neuroscience research 20060801 |
Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway. | Cell cycle (Georgetown, Tex.) 20060801 |
CDC25B phosphorylation by p38 and MK-2. | Cell cycle (Georgetown, Tex.) 20060801 |
Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species. | Cell cycle (Georgetown, Tex.) 20060801 |
Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin. | Diabetes 20060801 |
The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase. | Cell cycle (Georgetown, Tex.) 20060801 |
Cdk1/cyclin B-mediated phosphorylation stabilizes SREBP1 during mitosis. | Cell cycle (Georgetown, Tex.) 20060801 |
Participation of superoxide in neutrophil activation and cytokine production. | Biochimica et biophysica acta 20060801 |
Revealing successive steps of deprotonation of L- phosphoserine through 13C and 31P chemical shielding tensor fingerprints. | The journal of physical chemistry. A 20060727 |
Distinct signaling functions for Shc isoforms in the heart. | The Journal of biological chemistry 20060721 |
Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts. Role in suppression of c/EBP/NF-kappaB-mediated MEKK1-induced MMP-1 expression. | The Journal of biological chemistry 20060721 |
Response of human mammary epithelial cells to DNA damage induced by 4-hydroxyequilenin: Lack of p53-mediated G1 arrest. | Chemico-biological interactions 20060710 |
Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62. | FEBS letters 20060710 |
Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger. | Circulation 20060704 |
Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800. | Pain 20060701 |
Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway. | Immunity 20060701 |
Polo-like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation. | FEBS letters 20060626 |
Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription. | The EMBO journal 20060621 |
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. | The EMBO journal 20060621 |
Increased expression of LGI1 gene triggers growth inhibition and apoptosis of neuroblastoma cells. | Journal of cellular physiology 20060601 |
Phosphorylation of the p34(cdc2) target site on goldfish germinal vesicle lamin B3 before oocyte maturation. | European journal of cell biology 20060601 |
The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability. | Cell cycle (Georgetown, Tex.) 20060601 |
Posttranslational phosphorylation of mutant p53 protein in tumor development. | Medical molecular morphology 20060601 |
Rec8 phosphorylation and recombination promote the step-wise loss of cohesins in meiosis. | Nature 20060525 |
Protein serine/threonine phosphatase-1 dephosphorylates p53 at Ser-15 and Ser-37 to modulate its transcriptional and apoptotic activities. | Oncogene 20060518 |
Characterization of yeast pyruvate kinase 1 as a protein kinase A substrate, and specificity of the phosphorylation site sequence in the whole protein. | The Biochemical journal 20060515 |
Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts. | The Biochemical journal 20060515 |
Cardiac ryanodine receptor phosphorylation: target sites and functional consequences. | The Biochemical journal 20060515 |
Pigment epithelium-derived factor (PEDF) inhibits advanced glycation end product (AGE)-induced C-reactive protein expression in hepatoma cells by suppressing Rac-1 activation. | FEBS letters 20060515 |
Autophosphorylation of Akt at threonine 72 and serine 246. A potential mechanism of regulation of Akt kinase activity. | The Journal of biological chemistry 20060512 |
Hyperphosphorylation of tau induces local polyproline II helix. | Biochemistry 20060502 |
Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alpha. | The Biochemical journal 20060501 |
Metabolipidomics: profiling metabolism of glycerophospholipid species by stable isotopic precursors and tandem mass spectrometry. | Analytical biochemistry 20060501 |
Characterization of a monoclonal antibody B1 that recognizes phosphorylated Ser-158 in the activation peptide region of human coagulation factor IX. | The Journal of biological chemistry 20060407 |
HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060401 |
Molecular verification of stereotactic radiotherapy in rats using ATMpS1981 immunofluorescence. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060401 |
p14ARF triggers G2 arrest through ERK-mediated Cdc25C phosphorylation, ubiquitination and proteasomal degradation. | Cell cycle (Georgetown, Tex.) 20060401 |
The biochemical effect of Ser167 phosphorylation on Chlamydomonas reinhardtii centrin. | Biochemical and biophysical research communications 20060331 |
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase. | Molecular cell 20060317 |
Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4alpha transcriptional activity. | The Biochemical journal 20060301 |
Downregulation of protein kinase B/Akt-1 mediates INS-1 insulinoma cell apoptosis induced by dominant-negative suppression of hepatocyte nuclear factor-1alpha function. | Diabetologia 20060301 |
CDK9 phosphorylates p53 on serine residues 33, 315 and 392. | Cell cycle (Georgetown, Tex.) 20060301 |
Nek1 shares structural and functional similarities with NIMA kinase. | Biochimica et biophysica acta 20060301 |
Structural mechanism of plant aquaporin gating. | Nature 20060209 |
Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage. | Brain research 20060209 |
Antioxidative stress activity of oligophosphopeptides derived from hen egg yolk phosvitin in Caco-2 cells. | Journal of agricultural and food chemistry 20060208 |
Structure and desorption energetics of ultrathin D2O ice overlayers on serine- and serinephosphate-terminated self-assembled monolayers. | The journal of physical chemistry. B 20060202 |
Chemical derivatization of phosphoserine and phosphothreonine containing peptides to increase sensitivity for MALDI-based analysis and for selectivity of MS/MS analysis. | Proteomics 20060201 |
Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1. | Cell cycle (Georgetown, Tex.) 20060201 |
Structural basis of syndecan-4 phosphorylation as a molecular switch to regulate signaling. | Journal of molecular biology 20060127 |
Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125 |
Vasodilator-stimulated phosphoprotein (VASP) is phosphorylated on Ser157 by protein kinase C-dependent and -independent mechanisms in thrombin-stimulated human platelets. | The Biochemical journal 20060115 |
Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding. | The Journal of biological chemistry 20060113 |
Hydrolysis of phosphatidylserine-exposing red blood cells by secretory phospholipase A2 generates lysophosphatidic acid and results in vascular dysfunction. | The Journal of biological chemistry 20060113 |
ATM is activated by default in mitosis, localizes at centrosomes and monitors mitotic spindle integrity. | Cell cycle (Georgetown, Tex.) 20060101 |
UV photodissociation of phospho-seryl-containing peptides: laser stabilization of the phospho-seryl bond with multistage mass spectrometry. | Rapid communications in mass spectrometry : RCM 20060101 |
Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity. | BMC biochemistry 20060101 |
Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damage. | Methods in molecular biology (Clifton, N.J.) 20060101 |
TLR2- and TLR4-dependent activation of STAT1 serine phosphorylation in murine macrophages is protein kinase C-delta-independent. | Journal of endotoxin research 20060101 |
Spindle checkpoint protein hMad2 and histone H3 phosphoserine 10 mitosis marker in pediatric solid tumors. | Anticancer research 20060101 |
Individual and combined effects of methamphetamine and ketamine on conditioned place preference and NR1 receptor phosphorylation in rats. | Neuro-Signals 20060101 |
Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin. | Nature 20051222 |
Peripheral hyperinsulinemia promotes tau phosphorylation in vivo. | Diabetes 20051201 |
A universal assay for vitellogenin in fish mucus and plasma. | Environmental toxicology and chemistry 20051201 |
Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428. | The Biochemical journal 20051115 |
HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding. | The Journal of biological chemistry 20051111 |
The phosphorylation of Ser318 of insulin receptor substrate 1 is not per se inhibitory in skeletal muscle cells but is necessary to trigger the attenuation of the insulin-stimulated signal. | The Journal of biological chemistry 20051111 |
Cross-talk between the two divergent insulin signaling pathways is revealed by the protein kinase B (Akt)-mediated phosphorylation of adapter protein APS on serine 588. | The Journal of biological chemistry 20051111 |
Attenuated phosphorylation of heat shock protein 27 correlates with tumor progression in patients with hepatocellular carcinoma. | Biochemical and biophysical research communications 20051111 |
Calcium/calmodulin-dependent protein kinase II (CaMKII), through NMDA receptors and L-Voltage-gated channels, modulates the serine phosphorylation of GluR6 during cerebral ischemia and early reperfusion period in rat hippocampus. | Brain research. Molecular brain research 20051031 |
Septin1, a new interaction partner for human serine/threonine kinase aurora-B. | Biochemical and biophysical research communications 20051028 |
A phosphorylation-dependent export structure in ROMK (Kir 1.1) channel overrides an endoplasmic reticulum localization signal. | The Journal of biological chemistry 20051021 |
Genetic and post-mortem mRNA analysis of the 14-3-3 genes that encode phosphoserine/threonine-binding regulatory proteins in schizophrenia and bipolar disorder. | Schizophrenia research 20051015 |
Increases in intracellular calcium dephosphorylate histone H3 at serine 10 in human hepatoma cells: potential role of protein phosphatase 2A-protein kinase CbetaII complex. | Journal of cellular physiology 20051001 |
Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223. | Endocrinology 20051001 |
Method development and measurements of endogenous serine/threonine Akt phosphorylation using capillary electrophoresis for systems biology. | Electrophoresis 20051001 |
Phospho-eNOS Ser-114 in human mesenchymal stem cells: constitutive phosphorylation, nuclear localization and upregulation during mitosis. | European journal of cell biology 20051001 |
Lessons from nature: On the molecular recognition elements of the phosphoprotein binding-domains. | Biotechnology and bioengineering 20050905 |
Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells. | Journal of cellular physiology 20050901 |
Two proline-rich peptides from pig (Sus scrofa) salivary glands generated by pre-secretory pathway underlying the action of a proteinase cleaving ProAla bonds. | Peptides 20050901 |
Bradykinin preconditioning improves the profile of cell survival proteins and limits apoptosis after cardioplegic arrest. | Circulation 20050830 |
Keratin 8 phosphorylation by protein kinase C delta regulates shear stress-mediated disassembly of keratin intermediate filaments in alveolar epithelial cells. | The Journal of biological chemistry 20050826 |
14-3-3 proteins: a number of functions for a numbered protein. | Science's STKE : signal transduction knowledge environment 20050809 |
Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities. | The Journal of biological chemistry 20050805 |
Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-kappaB activation but not GSK3beta activity. | Apoptosis : an international journal on programmed cell death 20050801 |
Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding. | Journal of the American Chemical Society 20050713 |
Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713 |
c-Src: bridging the gap between phosphorylation- and acidification-induced gap junction channel closure. | Science's STKE : signal transduction knowledge environment 20050705 |
The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ. | The Biochemical journal 20050701 |
The influence of lidocaine and verapamil on the proliferation, CD44 expression and apoptosis behavior of human chondrocytes. | International journal of molecular medicine 20050701 |
Phosphorylation of p27(BBP)/eIF6 and its association with the cytoskeleton are developmentally regulated in Xenopus oogenesis. | Cellular and molecular life sciences : CMLS 20050701 |
Phosphoproteomic analysis with a solid-phase capture-release-tag approach. | Chemistry & biology 20050701 |
Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination. | Oncogene 20050623 |
Phosphorylation of Grb10 by mitogen-activated protein kinase: identification of Ser150 and Ser476 of human Grb10zeta as major phosphorylation sites. | Biochemistry 20050621 |
Silencing of p21-activated kinase attenuates vimentin phosphorylation on Ser-56 and reorientation of the vimentin network during stimulation of smooth muscle cells by 5-hydroxytryptamine. | The Biochemical journal 20050615 |
DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage. | Biochemistry 20050614 |
Phosphorylation of BAD at Ser-128 during mitosis and paclitaxel-induced apoptosis. | FEBS letters 20050606 |
Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals. | FEBS letters 20050606 |
Protein kinase CK2 phosphorylates and upregulates Akt/PKB. | Cell death and differentiation 20050601 |
Phosducin-like protein acts as a molecular chaperone for G protein betagamma dimer assembly. | The EMBO journal 20050601 |
Polo kinase links the stress pathway to cell cycle control and tip growth in fission yeast. | Nature 20050526 |
A phosphoserine-lysine salt bridge within an alpha-helical peptide, the strongest alpha-helix side-chain interaction measured to date. | Biochemistry 20050524 |
alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells. | Experimental cell research 20050515 |
Lower inhibitor development in hemophilia A mice following administration of recombinant factor VIII-O-phospho-L-serine complex. | The Journal of biological chemistry 20050506 |
Phosphorylation-specific prolyl isomerization: is there an underlying theme? | Nature cell biology 20050501 |
Identification of the regions of PECAM-1 involved in beta- and gamma-catenin associations. | Biochemical and biophysical research communications 20050422 |
Rapid enrichment and analysis of yeast phosphoproteins using affinity chromatography, 2D-PAGE and peptide mass fingerprinting. | Yeast (Chichester, England) 20050415 |
Binding mode and transcriptional activation potential of high affinity ligands for the CBP KIX domain. | Journal of the American Chemical Society 20050406 |
Modulation of insulin signalling by insulin sensitizers. | Biochemical Society transactions 20050401 |
14-3-3 proteins--an update. | Cell research 20050401 |
RNA-dependent cysteine biosynthesis in archaea. | Science (New York, N.Y.) 20050325 |
Sphingosine 1-phosphate analogs as receptor antagonists. | The Journal of biological chemistry 20050318 |
Regulation of plant symbiosis receptor kinase through serine and threonine phosphorylation. | The Journal of biological chemistry 20050311 |
Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation. | The Journal of biological chemistry 20050311 |
Consequences of lysine 72 mutation on the phosphorylation and activation state of cAMP-dependent kinase. | The Journal of biological chemistry 20050311 |
Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization. | The Journal of biological chemistry 20050311 |
Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway. | Diabetologia 20050301 |
Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1. | FEBS letters 20050227 |
Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry. | The Journal of biological chemistry 20050218 |
SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. | Molecular cell 20050218 |
Linking Smads and transcriptional activation. | The Biochemical journal 20050215 |
In vitro phosphorylation by cAMP-dependent protein kinase up-regulates recombinant Saccharomyces cerevisiae mannosylphosphodolichol synthase. | The Journal of biological chemistry 20050211 |
Effect of phosphorylation of ovalbumin on adsorption by aluminum-containing adjuvants and elution upon exposure to interstitial fluid. | Vaccine 20050210 |
Akt mediates the cross-talk between beta-adrenergic and insulin receptors in neonatal cardiomyocytes. | Circulation research 20050204 |
Another role for the celebrity: Akt and insulin resistance. | Circulation research 20050204 |
Activity-dependent neuroprotection and cAMP response element-binding protein (CREB): kinase coupling, stimulus intensity, and temporal regulation of CREB phosphorylation at serine 133. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202 |
The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo. | The Biochemical journal 20050201 |
Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050201 |
Phosphoserines on maize CENTROMERIC HISTONE H3 and histone H3 demarcate the centromere and pericentromere during chromosome segregation. | The Plant cell 20050201 |
Dynamic distribution of Ser-10 phosphorylated histone H3 in cytoplasm of MCF-7 and CHO cells during mitosis. | Cell research 20050201 |
Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205. | Proceedings of the National Academy of Sciences of the United States of America 20050125 |
Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors. | The Journal of biological chemistry 20050114 |
Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR). | The Journal of biological chemistry 20050114 |
Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation. | The Journal of biological chemistry 20050114 |
c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation. | The Journal of biological chemistry 20050114 |
Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase. | Biochemical and biophysical research communications 20050114 |
Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. | Molecular endocrinology (Baltimore, Md.) 20050101 |
Estrogen receptor activation of phosphoinositide-3 kinase, akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects. | Molecular pharmacology 20050101 |
A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C. | Journal of molecular and cellular cardiology 20050101 |
Roscovitine-induced up-regulation of p53AIP1 protein precedes the onset of apoptosis in human MCF-7 breast cancer cells. | Molecular cancer therapeutics 20050101 |
Novel phosphorylation of histone H3 at threonine 11 that temporally correlates with condensation of mitotic and meiotic chromosomes in plant cells. | Cytogenetic and genome research 20050101 |
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level. | Neuropharmacology 20050101 |
Phosphorylation of estrogen receptor alpha serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer. | Breast cancer research : BCR 20050101 |
Phosphorylation of RanGAP1 stabilizes its interaction with Ran and RanBP1. | Cell structure and function 20050101 |
[Huntington's disease: intracellular signaling pathways and neuronal death]. | Journal de la Societe de biologie 20050101 |
Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL. | The Biochemical journal 20041215 |
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. | The Biochemical journal 20041215 |
Beta-elimination coupled with tandem mass spectrometry for the identification of in vivo and in vitro phosphorylation sites in maize dehydrin DHN1 protein. | Biochemistry 20041214 |
Accumulation of inhibitory kappaB-alpha as a mechanism contributing to the anti-inflammatory effects of surfactant protein-A. | American journal of respiratory cell and molecular biology 20041201 |
Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere. | Journal of the American Chemical Society 20041201 |
The tube cement of Phragmatopoma californica: a solid foam. | The Journal of experimental biology 20041201 |
Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function. | Circulation research 20041126 |
Another new kinase targets troponin I. | Circulation research 20041126 |
Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110 |
Photocontrol of Smad2, a multiphosphorylated cell-signaling protein, through caging of activating phosphoserines. | Angewandte Chemie (International ed. in English) 20041105 |
Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis. | Blood 20041015 |
Phosphorylation of androgen receptor isoforms. | The Biochemical journal 20041015 |
Integrin-linked kinase regulates the nuclear entry of the c-Jun coactivator alpha-NAC and its coactivation potency. | The Journal of biological chemistry 20041015 |
Semiconductor-encapsulated peptide-amphiphile nanofibers. | Journal of the American Chemical Society 20041013 |
Synergistic activation of CREB-mediated transcription by forskolin and phorbol ester requires PKC and depends on the glutamine-rich Q2 transactivation domain. | Cellular signalling 20041001 |
PTH and phospholipase A2 in the aging process of intestinal cells. | Journal of cellular biochemistry 20041001 |
Akt/protein kinase B and endothelial nitric oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer. | Circulation 20040921 |
cAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular smooth muscle cell migration. | Arteriosclerosis, thrombosis, and vascular biology 20040901 |
Characterization of protein tyrosine phosphatase activity in rat liver microsomes: suppressive effect of endogenous regucalcin in transgenic rats. | International journal of molecular medicine 20040901 |
Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser1177 via an AMPK mediated pathway independent of PI3K-Akt. | FEBS letters 20040827 |
Senescence marker protein-30 regulates Akt activity and contributes to cell survival in Hep G2 cells. | Biochemical and biophysical research communications 20040820 |
Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375. | The EMBO journal 20040818 |
Phosphorylated alpha-synuclein in normal mouse brain. | FEBS letters 20040813 |
Identification of novel phosphorylation sites on postsynaptic density proteins. | Biochemical and biophysical research communications 20040813 |
Changes in AMPA receptor phosphorylation in the rostral ventromedial medulla after inflammatory hyperalgesia in rats. | Neuroscience letters 20040812 |
c-Fos phosphorylation induced by H2O2 prevents proteasomal degradation of c-Fos in cardiomyocytes. | The Journal of biological chemistry 20040806 |
Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminals. | The Biochemical journal 20040801 |
Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes. | Molecular endocrinology (Baltimore, Md.) 20040801 |
Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
L-CCG-I activates group III metabotropic glutamate receptors in the hippocampal CA3 region. | Neuropharmacology 20040801 |
Overexpression of tau leads to the stimulation of neurite outgrowth, the activation of caspase 3 activity, and accumulation and phosphorylation of tau in neuroblastoma cells on cAMP treatment. | Neuroscience research 20040801 |
Analysis of protein phosphorylation by hypothesis-driven multiple-stage mass spectrometry. | Analytical chemistry 20040801 |
Regulation of dopamine D-receptor activation in vivo by protein phosphatase 2B (calcineurin). | Journal of neurochemistry 20040801 |
How calcium inhibits the magnesium-dependent enzyme human phosphoserine phosphatase. | European journal of biochemistry 20040801 |
Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry. | Electrophoresis 20040801 |
Chemical segregation and reduction of Raman background interference using drop coating deposition. | Applied spectroscopy 20040801 |
Mitogen-activated protein kinases mediate the oxidative burst and saponin synthesis induced by chitosan in cell cultures of Panax ginseng. | Science in China. Series C, Life sciences 20040801 |
Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site. | FEBS letters 20040730 |
Parathyroid-hormone-related protein as a regulator of pRb and the cell cycle in arterial smooth muscle. | Circulation 20040713 |
A small heat shock protein from Artemia franciscana is phosphorylated at serine 50. | Biochimica et biophysica acta 20040701 |
Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53. | FEBS letters 20040604 |
Mechanism and importance of post-translational regulation of nitrate reductase. | Journal of experimental botany 20040601 |
Downregulation of beta-catenin by p53 involves changes in the rate of beta-catenin phosphorylation and Axin dynamics. | Oncogene 20040527 |
Binding of RNA to p53 regulates its oligomerization and DNA-binding activity. | Oncogene 20040527 |
Limited role of N-terminal phosphoserine residues in the activation of transcription by p53. | Oncogene 20040527 |
Semisynthesis of phosphovariants of Smad2 reveals a substrate preference of the activated T beta RI kinase. | Biochemistry 20040518 |
Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2. | The Biochemical journal 20040515 |
Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. | The Journal of biological chemistry 20040514 |
Leukemia inhibitory factor activates cardiac L-Type Ca2+ channels via phosphorylation of serine 1829 in the rabbit Cav1.2 subunit. | Circulation research 20040514 |
Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells. | Circulation research 20040514 |
TAF1 activates transcription by phosphorylation of serine 33 in histone H2B. | Science (New York, N.Y.) 20040514 |
Influence of electric charge variation at residues 209 and 159 on the interaction of eIF4E with the mRNA 5' terminus. | Biochemistry 20040511 |
Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells. | The Biochemical journal 20040501 |
Reduced NOS3 phosphorylation mediates reduced NO/cGMP signaling in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20040501 |
Identifying protein kinase substrates: hunting for the organ-grinder's monkeys. | Trends in biochemical sciences 20040501 |
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. | The EMBO journal 20040421 |
JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins. | The EMBO journal 20040421 |
Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy. | Circulation research 20040416 |
Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation. | Oncogene 20040415 |
Master of all things phosphorylated. | The Biochemical journal 20040415 |
Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. | Circulation research 20040402 |
Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta. | The Biochemical journal 20040401 |
Comparative expression of NFkappaB proteins in melanocytes of normal skin vs. benign intradermal naevus and human metastatic melanoma biopsies. | Pigment cell research 20040401 |
Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle. | Diabetes 20040401 |
Pinning down cell signaling, cancer and Alzheimer's disease. | Trends in biochemical sciences 20040401 |
Phosphoserine--a convenient compound for modification of calcium phosphate bone cement collagen composites. | Journal of materials science. Materials in medicine 20040401 |
Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6). | Circulation research 20040305 |
Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location. | The Biochemical journal 20040301 |
Arsenic trioxide and paclitaxel induce apoptosis by different mechanisms. | Cell cycle (Georgetown, Tex.) 20040301 |
Inhibition of cdk1 by alsterpaullone and thioflavopiridol correlates with increased transit time from mid G2 through prophase. | Cell cycle (Georgetown, Tex.) 20040301 |
Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line. | Molecular & cellular proteomics : MCP 20040301 |
On the evolution of erythrocyte programmed cell death: apoptosis of Rana esculenta nucleated red blood cells involves cysteine proteinase activation and mitochondrion permeabilization. | Biochimie 20040301 |
Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis. | The Journal of biological chemistry 20040227 |
Phospho-serine-118 estrogen receptor-alpha detection in human breast tumors in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040215 |
[Ser2]- and [SerP2] incretin analogs: comparison of dipeptidyl peptidase IV resistance and biological activities in vitro and in vivo. | The Journal of biological chemistry 20040206 |
Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors. | Biochemistry 20040203 |
The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2. | Blood 20040201 |
Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons. | Cell death and differentiation 20040201 |
Molecular cloning and characterization of two different cDNAs encoding the molecular chaperone Hsp90 in the oomycete Achlya ambisexualis. | Fungal genetics and biology : FG & B 20040201 |
Expression and secretion of functional recombinant scu-PA:AV in insect cell using signal peptides. | Protein and peptide letters 20040201 |
The charged milieu: a major player in fertilization reactions. | Acta histochemica 20040201 |
Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling. | Annales d'endocrinologie 20040201 |
SH2-B is a positive regulator of nerve growth factor-mediated activation of the Akt/Forkhead pathway in PC12 cells. | The Journal of biological chemistry 20040102 |
Activation of group III metabotropic glutamate receptors in selected regions of the basal ganglia alleviates akinesia in the reserpine-treated rat. | British journal of pharmacology 20040101 |
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. | Diabetes 20040101 |
Characterization of agonist stimulation of cAMP-dependent protein kinase and G protein-coupled receptor kinase phosphorylation of the beta2-adrenergic receptor using phosphoserine-specific antibodies. | Molecular pharmacology 20040101 |
Cell cycle arrest by monochloramine through the oxidation of retinoblastoma protein. | Free radical biology & medicine 20040101 |
TIAF1 and p53 functionally interact in mediating apoptosis and silencing of TIAF1 abolishes nuclear translocation of serine 15-phosphorylated p53. | DNA and cell biology 20040101 |
The use of in vitro peptide-library screens in the analysis of phosphoserine/threonine-binding domain structure and function. | Annual review of biophysics and biomolecular structure 20040101 |
Analyzing the regulation and function of ATM. | Methods in molecular biology (Clifton, N.J.) 20040101 |
Changes in sperm glycogen synthase kinase-3 serine phosphorylation and activity accompany motility initiation and stimulation. | Journal of andrology 20040101 |
Talin distribution during the differentiation of satellite cells isolated from rat skeletal muscle. | Cellular & molecular biology letters 20040101 |
Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains. | The Journal of biological chemistry 20031226 |
Protein phosphatase 1 binds to phospho-Ser-1394 of the macrophage-stimulating protein receptor. | The Biochemical journal 20031215 |
Improved beta-elimination-based affinity purification strategy for enrichment of phosphopeptides. | Analytical chemistry 20031215 |
Changes in JNK1 activity in the frog (Rana esculenta) testis. | Molecular reproduction and development 20031201 |
CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis. | Nature structural biology 20031201 |
Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats. | Diabetologia 20031201 |
Dependence of the interfacial behavior of beta-casein on phosphoserine residues. | Journal of dairy science 20031201 |
Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence. | The Journal of biological chemistry 20031128 |
Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro. | Biochimica et biophysica acta 20031120 |
Influence of immobilization stress on the expression and phosphatase activity of protein phosphatase 2A in the rat brain. | Biological psychiatry 20031115 |
Differentiation between acetylcholinesterase and the organophosphate-inhibited form using antibodies and the correlation of antibody recognition with reactivation mechanism and rate. | The Journal of biological chemistry 20031114 |
Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II. | Cell 20031114 |
Silent cleanup of very early apoptotic cells by macrophages. | Journal of immunology (Baltimore, Md. : 1950) 20031101 |
MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632. | Diabetologia 20031101 |
Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins. | Biochemistry 20031028 |
BRCT repeats as phosphopeptide-binding modules involved in protein targeting. | Science (New York, N.Y.) 20031024 |
The BRCT domain is a phospho-protein binding domain. | Science (New York, N.Y.) 20031024 |
Bradykinin B1 receptor stimulates the proximal tubule Na(+)-ATPase activity through protein kinase C pathway. | Regulatory peptides 20031015 |
Phosphoprotein isotope-coded solid-phase tag approach for enrichment and quantitative analysis of phosphopeptides from complex mixtures. | Analytical chemistry 20031015 |
Phosphorylation of insulin receptor substrate-1 serine 307 correlates with JNK activity in atrophic skeletal muscle. | FEBS letters 20031009 |
Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase. | Free radical biology & medicine 20031001 |
A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8. | Science (New York, N.Y.) 20030919 |
Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases. | The EMBO journal 20030915 |
Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T. | The Journal of biological chemistry 20030912 |
Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation. | The Journal of biological chemistry 20030912 |
Prolonged survival of the phosphorylated form of rhodopsin during dark adaptation of Royal College Surgeons rat. | FEBS letters 20030911 |
A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1. | FEBS letters 20030911 |
Phagocytosis of apoptotic inflammatory cells by microglia and its therapeutic implications: termination of CNS autoimmune inflammation and modulation by interferon-beta. | Glia 20030901 |
Phosphospecific proteolysis for mapping sites of protein phosphorylation. | Nature biotechnology 20030901 |
Inhibition of interferon gamma signaling by the short chain fatty acid butyrate. | Molecular cancer research : MCR 20030901 |
Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins. | The Journal of biological chemistry 20030829 |
Fluorescent caged phosphoserine peptides as probes to investigate phosphorylation-dependent protein associations. | Journal of the American Chemical Society 20030827 |
Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis. | The Journal of biological chemistry 20030801 |
Molecular mechanism for growth suppression of human hepatocellular carcinoma cells by acyclic retinoid. | Carcinogenesis 20030801 |
Synthesis of a radioactive thiol reagent, 1-S-[3H]carboxymethyl-dithiothreitol: identification of the phosphorylation sites by N-terminal peptide sequencing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | Analytical biochemistry 20030801 |
Novel effect of N-palmitoyl-L-serine phosphoric acid on cytosolic Ca2+ levels in human osteoblasts. | Pharmacology & toxicology 20030801 |
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. | Nature 20030731 |
EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes. | Journal of cellular physiology 20030701 |
Activation of protein kinase C delta by IFN-gamma. | Journal of immunology (Baltimore, Md. : 1950) 20030701 |
Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages. | The Journal of biological chemistry 20030620 |
Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation. | The Journal of biological chemistry 20030620 |
Control of synaptic strength, a novel function of Akt. | Neuron 20030619 |
Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression. | Science (New York, N.Y.) 20030613 |
A new approach to phosphoserine and phosphothreonine analysis in peptides and proteins: chemical modification, enrichment via solid-phase reversible binding, and analysis by mass spectrometry. | Analytical and bioanalytical chemistry 20030601 |
Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes. | Diabetes 20030601 |
MAP kinases couple multiple functions of human progesterone receptors: degradation, transcriptional synergy, and nuclear association. | The Journal of steroid biochemistry and molecular biology 20030601 |
ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1. | The Journal of biological chemistry 20030523 |
Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling. | The Journal of biological chemistry 20030523 |
High glucose inhibits insulin-stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser1177 phosphorylation in human aortic endothelial cells. | The Journal of biological chemistry 20030523 |
Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb. | The Journal of biological chemistry 20030523 |
IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress. | Diabetologia 20030501 |
Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast. | Science (New York, N.Y.) 20030418 |
DNA-dependent acetylation of p53 by the transcription coactivator p300. | The Journal of biological chemistry 20030411 |
Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex. | The Journal of biological chemistry 20030411 |
Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts. | The Journal of biological chemistry 20030411 |
Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity. | The Journal of biological chemistry 20030411 |
An experimental and theoretical study of the 13C and 31P chemical shielding tensors in solid O-phosphorylated amino acids. | Journal of the American Chemical Society 20030409 |
IRAK-dependent phosphorylation of Stat1 on serine 727 in response to interleukin-1 and effects on gene expression. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20030401 |
New perspectives on the regulation of intermembrane glycerophospholipid traffic. | Journal of lipid research 20030301 |
Direct and indirect interactions between cannabinoid CB1 receptor and group II metabotropic glutamate receptor signalling in layer V pyramidal neurons from the rat prefrontal cortex. | The European journal of neuroscience 20030301 |
Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and 10, and demonstrates that novel anticancer retinoid-related molecules induce apoptosis via the intrinsic pathway. | Molecular cancer therapeutics 20030301 |
Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine. | Experimental neurology 20030301 |
Human recombinant anti-La (SS-B) autoantibodies demonstrate the accumulation of phosphoserine-366-containing la isoforms in nucleoplasmic speckles. | European journal of cell biology 20030301 |
Reconstitution of water channel function of an aquaporin overexpressed and purified from Pichia pastoris. | FEBS letters 20030227 |
Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. | Science (New York, N.Y.) 20030221 |
Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341. | Blood 20030215 |
Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030201 |
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. | The Journal of biological chemistry 20030131 |
The requirement of specific membrane domains for Raf-1 phosphorylation and activation. | The Journal of biological chemistry 20030131 |
Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12. | Nature 20030109 |
PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain. | The EMBO journal 20030102 |
Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen. | American journal of physiology. Endocrinology and metabolism 20030101 |
Protein phosphatase-2A restricts migration of Lewis lung carcinoma cells by modulating the phosphorylation of focal adhesion proteins. | International journal of cancer 20030101 |
Synthesis and immunogenic properties of phosphopeptides related to the human insulin receptor. | The journal of peptide research : official journal of the American Peptide Society 20030101 |
Chemical modifications of proteins as an aid to sequence analysis. | Methods in molecular biology (Clifton, N.J.) 20030101 |
Analysis of sites of protein phosphorylation. | Methods in molecular biology (Clifton, N.J.) 20030101 |
Metal ion complexes in the structural analysis of phospholipids by electrospray ionization tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20030101 |
Analysis of class I phosphoinositide 3-kinase autophosphorylation sites by mass spectrometry. | Rapid communications in mass spectrometry : RCM 20030101 |
Molecular plasticity in the rat auditory brainstem: modulation of expression and distribution of phosphoserine, phospho-CREB and TrkB after noise trauma. | Audiology & neuro-otology 20030101 |
Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants. | Clinical & experimental metastasis 20030101 |
Distribution and potential role of cytosolic water-soluble phosphodiesters in fish. | Physiological and biochemical zoology : PBZ 20030101 |
Gamma irradiation results in phosphorylation of p53 at serine-392 in human T-lymphocyte leukaemia cell line MOLT-4. | Folia biologica 20030101 |
Phosphorylation of glycogen synthase kinase-3beta at serine-9 by phospholipase Cgamma1 through protein kinase C in rat 3Y1 fibroblasts. | Experimental & molecular medicine 20021231 |
A tumor-specific kinase activity regulates the viral death protein Apoptin. | The Journal of biological chemistry 20021227 |
Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest. | Journal of cell science 20021201 |
Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects. | Endocrinology 20021201 |
Cocaine treatment- and withdrawal-induced alterations in the expression and serine phosphorylation of the NR1 NMDA receptor subunit. | Psychopharmacology 20021201 |
The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase. | Biological chemistry 20021201 |
TFIIF-associating carboxyl-terminal domain phosphatase dephosphorylates phosphoserines 2 and 5 of RNA polymerase II. | The Journal of biological chemistry 20021129 |
A new dipeptide, O-phosphoserylethanolamine isolated from Agkistroden blomhoffi (mamushi). | Archives of biochemistry and biophysics 20021115 |
Dissection of c-MOS degron. | The EMBO journal 20021115 |
Identification of phosphoserine and phosphothreonine as cysteic acid and beta-methylcysteic acid residues in peptides by tandem mass spectrometric sequencing. | Analytical chemistry 20021115 |
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. | The Journal of biological chemistry 20021108 |
Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A. | The Journal of biological chemistry 20021108 |
Identification and functional analysis of novel phosphorylation sites in Cx43 in rat primary granulosa cells. | FEBS letters 20021106 |
Increased methamphetamine-induced locomotor activity and behavioral sensitization in histamine-deficient mice. | Journal of neurochemistry 20021101 |
Identification of phosphorylation sites in the polo-like kinases Plx1 and Plk1 by a novel strategy based on element and electrospray high resolution mass spectrometry. | Proteomics 20021101 |
Decorin affects endothelial cells by Akt-dependent and -independent pathways. | Annals of the New York Academy of Sciences 20021101 |
Self-assembly of highly phosphorylated silaffins and their function in biosilica morphogenesis. | Science (New York, N.Y.) 20021018 |
A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation. | The EMBO journal 20021015 |
Myelin proteolipid protein, basic protein, the small isoform of myelin-associated glycoprotein, and p42MAPK are associated in the Triton X-100 extract of central nervous system myelin. | Journal of neuroscience research 20021001 |
14-3-3 regulates actin dynamics by stabilizing phosphorylated cofilin. | Current biology : CB 20021001 |
Amphetamine increases phosphorylation of extracellular signal-regulated kinase and transcription factors in the rat striatum via group I metabotropic glutamate receptors. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021001 |
Retinoic acid modulates gap junctional intercellular communication in hepatocytes and hepatoma cells. | Cellular and molecular life sciences : CMLS 20021001 |
PrpE, a PPP protein phosphatase from Bacillus subtilis with unusual substrate specificity. | The Biochemical journal 20020915 |
Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha. | The Journal of biological chemistry 20020906 |
Protein serine and threonine phosphorylation, hyperactivation and acrosome reaction in in vitro capacitated hamster spermatozoa. | Molecular reproduction and development 20020901 |
Phosphorylation of neuronal nitric oxide synthase at Ser847 by CaM-KII in the hippocampus of rat brain after transient forebrain ischemia. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020901 |
Regulation of histone deacetylase 2 by protein kinase CK2. | The Journal of biological chemistry 20020830 |
General method for the synthesis of caged phosphopeptides: tools for the exploration of signal transduction pathways. | Organic letters 20020822 |
Antibody-based fluorescence detection of kinase activity on a peptide array. | Bioorganic & medicinal chemistry letters 20020819 |
Stereoselective synthesis of alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, via electrophilic fluorination of lithiated bis-lactim ethers. | Chemical communications (Cambridge, England) 20020807 |
Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line. | The Journal of biological chemistry 20020802 |
Resveratrol induced serine phosphorylation of p53 causes apoptosis in a mutant p53 prostate cancer cell line. | The Journal of urology 20020801 |
Measurement of IKK activity in primary rat T cells: rapid activation and inactivation. | Journal of immunological methods 20020801 |
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists. | Diabetes 20020801 |
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. | The EMBO journal 20020801 |
The death domain of NF-kappa B1 p105 is essential for signal-induced p105 proteolysis. | The Journal of biological chemistry 20020705 |
Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation. | The Journal of biological chemistry 20020705 |
AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling. | The Journal of biological chemistry 20020705 |
Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism. | Nature structural biology 20020701 |
Neutrophil transepithelial migration: evidence for sequential, contact-dependent signaling events and enhanced paracellular permeability independent of transjunctional migration. | Journal of immunology (Baltimore, Md. : 1950) 20020701 |
A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression. | The EMBO journal 20020701 |
Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK. | The EMBO journal 20020701 |
Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol. | Molecular carcinogenesis 20020701 |
Control of the glycolytic gapA operon by the catabolite control protein A in Bacillus subtilis: a novel mechanism of CcpA-mediated regulation. | Molecular microbiology 20020701 |
Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues. | European journal of biochemistry 20020701 |
A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate. | Molecular & cellular proteomics : MCP 20020701 |
Biphasic regulation of extracellular-signal-regulated protein kinase by leptin in macrophages: role in regulating STAT3 Ser727 phosphorylation and DNA binding. | The Biochemical journal 20020615 |
Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615 |
Promoter of FGF8 reveals a unique regulation by unliganded RARalpha. | Journal of molecular biology 20020607 |
alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI. | American journal of physiology. Heart and circulatory physiology 20020601 |
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation. | Genes & development 20020601 |
Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. | Cell 20020517 |
Rapamycin partially prevents insulin resistance induced by chronic insulin treatment. | Biochemical and biophysical research communications 20020510 |
Aurora-B associated protein phosphatases as negative regulators of kinase activation. | Oncogene 20020509 |
Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation. | FEBS letters 20020508 |
Effect of phosphorylation on the structure and fold of transactivation domain of p53. | The Journal of biological chemistry 20020503 |
Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway. | The Journal of biological chemistry 20020503 |
Protein kinase C inhibits type VI adenylyl cyclase by phosphorylating the regulatory N domain and two catalytic C1 and C2 domains. | The Journal of biological chemistry 20020503 |
Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020501 |
Monitoring the interfacial capacitance at self-assembled phosphate monolayers on gold electrodes upon interaction with calcium and magnesium. | Analytical chemistry 20020501 |
Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein. | Biochemistry 20020430 |
Increased serine phosphorylation and activation of STAT1 by oncogenic Ras transfection. | Molecules and cells 20020430 |
Isolation of a cDNA for a nucleoside diphosphate kinase capable of phosphorylating the kinase domain of the self-incompatibility factor SRK of Brassica campestris. | Journal of experimental botany 20020401 |
Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020401 |
Interaction between vanilloid and glutamate receptors in the central modulation of nociception. | European journal of pharmacology 20020329 |
Nitric-oxide-synthase-mediated cyclic guanosine monophosphate production in neonatal rat cerebellar prisms is resistant to calcineurin inhibition. | Neuroscience letters 20020329 |
Phosphorylation of HDM2 by Akt. | Oncogene 20020327 |
Apolipoprotein E activates Akt pathway in neuro-2a in an isoform-specific manner. | Biochemical and biophysical research communications 20020322 |
SN2 DNA-alkylating agent-induced phosphorylation of p53 and activation of p21 gene expression. | Mutation research 20020320 |
Defective Akt activation is associated with glucose- but not glucosamine-induced insulin resistance. | American journal of physiology. Endocrinology and metabolism 20020301 |
Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome. | The Biochemical journal 20020301 |
Cutting Edge: Internalization of transduced E-selectin by cultured human endothelial cells: comparison of dermal microvascular and umbilical vein cells and identification of a phosphoserine-type di-leucine motif. | Journal of immunology (Baltimore, Md. : 1950) 20020301 |
Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise. | Diabetes 20020301 |
14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1. | Molecular endocrinology (Baltimore, Md.) 20020301 |
Store depletion-induced calcium influx in rat cerebellar astrocytes. | British journal of pharmacology 20020301 |
Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20. | Oncogene 20020227 |
Identification of a novel phosphorylation site, Ser-170, as a regulator of bad pro-apoptotic activity. | The Journal of biological chemistry 20020222 |
Active Rho kinase (ROK-alpha ) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells. | The Journal of biological chemistry 20020222 |
Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2. | The Journal of biological chemistry 20020222 |
Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway. | The Journal of biological chemistry 20020222 |
Cutting edge: Transcriptional activity of NFATc1 is enhanced by the Pim-1 kinase. | Journal of immunology (Baltimore, Md. : 1950) 20020215 |
Activation of ATM and phosphorylation of p53 by heat shock. | Oncogene 20020207 |
Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A. | The Journal of biological chemistry 20020201 |
Inhibition of protein phosphatase-1 is linked to phosphorylation of p53 and apoptosis. | Apoptosis : an international journal on programmed cell death 20020201 |
Ser-474 is the major target of insulin-mediated phosphorylation of protein kinase B beta in primary rat adipocytes. | Cellular signalling 20020201 |
The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes. | Molecular endocrinology (Baltimore, Md.) 20020201 |
Signal transduction and the control of gene expression. | Science (New York, N.Y.) 20020201 |
Phosphorylation of retinoid X receptor suppresses its ubiquitination in human hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20020201 |
Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry. | Journal of mass spectrometry : JMS 20020201 |
Regulation of p73 by c-Abl through the p38 MAP kinase pathway. | Oncogene 20020131 |
Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1. | FEBS letters 20020130 |
Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function. | The Journal of biological chemistry 20020125 |
Inhibition of the Bcr-Abl oncoprotein by Bcr requires phosphoserine 354. | Cancer research 20020115 |
p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. | Nature immunology 20020101 |
Preparing the target for the bullet. | Nature immunology 20020101 |
A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro. | Diabetes 20020101 |
Phosphoserine-dependent regulation of protein-protein interactions in the Smad pathway. | Structure (London, England : 1993) 20020101 |
Selective effect of cholesterylphosphoserine on intracellular cholesterol transport. | Lipids 20020101 |
Protein phosphatase-2A modulates the serine and tyrosine phosphorylation of paxillin in Lewis lung carcinoma tumor variants. | Clinical & experimental metastasis 20020101 |
A pool of beta-tubulin is hyperphosphorylated at serine residues in Alzheimer disease brain. | FEBS letters 20011214 |
Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart. | Diabetes 20011201 |
Development and validation of a competitive AKT serine/threonine kinase fluorescence polarization assay using a product-specific anti-phospho-serine antibody. | Analytical biochemistry 20011201 |
Angiotensin II promotes the phosphorylation of cyclic AMP-responsive element binding protein (CREB) at Ser133 through an ERK1/2-dependent mechanism. | Journal of neurochemistry 20011201 |
Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling. | Molecular cell 20011201 |
Self-assembling materials. Coated nanofibers copy what's bred in the bone. | Science (New York, N.Y.) 20011123 |
Self-assembly and mineralization of peptide-amphiphile nanofibers. | Science (New York, N.Y.) 20011123 |
Phosphopeptide derivatization signatures to identify serine and threonine phosphorylated peptides by mass spectrometry. | Analytical chemistry 20011115 |
cAMP response element-binding protein mediates thrombin-induced proliferation of vascular smooth muscle cells. | Arteriosclerosis, thrombosis, and vascular biology 20011101 |
Galpha(i2) enhances insulin signaling via suppression of protein-tyrosine phosphatase 1B. | The Journal of biological chemistry 20011026 |
Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression. | Molecular and cellular endocrinology 20011025 |
Group I metabotropic glutamate receptor activation increases phosphorylation of cAMP response element-binding protein, Elk-1, and extracellular signal-regulated kinases in rat dorsal striatum. | Brain research. Molecular brain research 20011019 |
Difference in the centrosome duplication regulatory activity among p53 'hot spot' mutants: potential role of Ser 315 phosphorylation-dependent centrosome binding of p53. | Oncogene 20011018 |
The 2,3-bisphosphoglycerate-independent phosphoglycerate mutase from Trypanosoma brucei: metal-ion dependency and phosphoenzyme formation. | FEMS microbiology letters 20011016 |
PKCbeta modulates antigen receptor signaling via regulation of Btk membrane localization. | The EMBO journal 20011015 |
Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription. | The EMBO journal 20011015 |
Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway. | Science (New York, N.Y.) 20011012 |
Regulation of Ca(2+)/calmodulin-dependent protein kinase kinase alpha by cAMP-dependent protein kinase: II. Mutational analysis. | Journal of biochemistry 20011001 |
Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor. | Molecular endocrinology (Baltimore, Md.) 20011001 |
Phosphorylation of the 24p3 protein secreted from mouse uterus in vitro and in vivo. | Journal of protein chemistry 20011001 |
Protein phosphatase 2A interacts with the Src kinase substrate p130(CAS). | Oncogene 20010920 |
Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68. | Cellular immunology 20010915 |
Leucine and insulin activate p70 S6 kinase through different pathways in human skeletal muscle. | American journal of physiology. Endocrinology and metabolism 20010901 |
Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway. | Journal of lipid research 20010901 |
Matrix Gla protein in Xenopus laevis: molecular cloning, tissue distribution, and evolutionary considerations. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010901 |
Polypeptide synthesis using an expressed peptide as a building block for condensation with a peptide thioester: application to the synthesis of phosphorylated p21Max protein(1-101). | Journal of peptide science : an official publication of the European Peptide Society 20010901 |
Phosphorylation of serine-rich protein encoded by open reading frame 3 of the TT virus genome. | Biochemical and biophysical research communications 20010817 |
Cell cycle regulation of myosin-V by calcium/calmodulin-dependent protein kinase II. | Science (New York, N.Y.) 20010817 |
Snf1--a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. | Science (New York, N.Y.) 20010810 |
Multiple phosphorylation of membrane-associated calcium-dependent protein serine/threonine kinase in Streptomyces fradiae. | FEMS microbiology letters 20010807 |
Zipper-interacting protein kinase induces Ca(2+)-free smooth muscle contraction via myosin light chain phosphorylation. | The Journal of biological chemistry 20010803 |
Interleukin 2 activates nuclear phospholipase Cbeta by mitogen-activated protein kinase-dependent phosphorylation in human natural killer cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801 |
Detection of calmodulin-binding proteins and calmodulin-dependent phosphorylation linked to calmodulin-dependent chemotaxis to folic and cAMP in Dictyostelium. | Cellular signalling 20010801 |
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation. | Journal of neurochemistry 20010801 |
Phosphorylation by PKA of a site unique to B-Raf kinase. | Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 20010801 |
Purification and structural determination of a phosphorylated peptide with anti-calcification and chitin-binding activities in the exoskeleton of the crayfish, Procambarus clarkii. | Bioscience, biotechnology, and biochemistry 20010801 |
Phosphorylation of RNA polymerase II CTD fragments results in tight binding to the WW domain from the yeast prolyl isomerase Ess1. | Biochemistry 20010724 |
Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid. | European journal of pharmacology 20010720 |
Phosphorylation of human plasma alpha2-Heremans-Schmid glycoprotein (human fetuin) in vivo. | The Biochemical journal 20010715 |
Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain. | The EMBO journal 20010702 |
Structure of GSK3beta reveals a primed phosphorylation mechanism. | Nature structural biology 20010701 |
Elevated levels of group-III metabotropic glutamate receptors in the inferior colliculus of genetically epilepsy-prone rats following intracollicular administration of L-serine-O-phosphate. | Journal of neurochemistry 20010701 |
MALDI-PSD-MS analysis of the phosphorylation sites of caseinomacropeptide. | Peptides 20010701 |
The chloroplastic glutamine synthetase (GS-2) of tobacco is phosphorylated and associated with 14-3-3 proteins inside the chloroplast. | Planta 20010701 |
Molecular determinants of the interaction between the inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate (IRAG) and cGMP kinase Ibeta. | The Journal of biological chemistry 20010629 |
DNA binding of TEA/ATTS domain factors is regulated by protein kinase C phosphorylation in human choriocarcinoma cells. | The Journal of biological chemistry 20010629 |
Modulation of the G protein regulator phosducin by Ca2+/calmodulin-dependent protein kinase II phosphorylation and 14-3-3 protein binding. | The Journal of biological chemistry 20010629 |
Signal transduction: signaling specificity- a complex affair. | Science (New York, N.Y.) 20010629 |
Possible implication of the Golgi apparatus casein kinase in the phosphorylation of vesicle docking protein p115 Ser-940: a study with peptide substrates. | Biochemical and biophysical research communications 20010615 |
Identification of a novel phosphorylation site in human androgen receptor by mass spectrometry. | Biochemical and biophysical research communications 20010615 |
Phosphorylation of plant actin-depolymerising factor by calmodulin-like domain protein kinase. | FEBS letters 20010615 |
Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition. | Cell 20010615 |
A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation. | Science (New York, N.Y.) 20010608 |
Synergism between nitric oxide and hydrogen peroxide in the inhibition of platelet function: the roles of soluble guanylyl cyclase and vasodilator-stimulated phosphoprotein. | Nitric oxide : biology and chemistry 20010601 |
GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex. | Antioxidants & redox signaling 20010601 |
Inhibitory effect of regucalcin on protein phosphatase activity in the nuclei of rat kidney cortex. | Journal of cellular biochemistry 20010601 |
Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila. | Nature 20010517 |
ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation. | The Journal of biological chemistry 20010511 |
Ca2+-independent smooth muscle contraction. a novel function for integrin-linked kinase. | The Journal of biological chemistry 20010511 |
Reciprocal phosphorylation and regulation of endothelial nitric-oxide synthase in response to bradykinin stimulation. | The Journal of biological chemistry 20010511 |
TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells. | American journal of physiology. Cell physiology 20010501 |
Protein kinase C-mediated desensitization of the neurokinin 1 receptor. | American journal of physiology. Cell physiology 20010501 |
Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata. | Journal of neurophysiology 20010501 |
Interaction of phosphorylated tyrosine hydroxylase with 14-3-3 proteins: evidence for a phosphoserine 40-dependent association. | Journal of neurochemistry 20010501 |
Functional replacement of the essential ESS1 in yeast by the plant parvulin DlPar13. | The Journal of biological chemistry 20010427 |
Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR. | The Journal of biological chemistry 20010427 |
Different usage of the glycosaminoglycan attachment sites of biglycan. | The Journal of biological chemistry 20010420 |
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1. | The Journal of biological chemistry 20010420 |
HIV-1 Tat protein interacts with mammalian capping enzyme and stimulates capping of TAR RNA. | The Journal of biological chemistry 20010420 |
Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization. | The Journal of biological chemistry 20010420 |
Lysophosphatidic acid-independent platelet activation by low-density lipoprotein. | FEBS letters 20010406 |
Phosphoserine/threonine-binding domains. | Current opinion in cell biology 20010401 |
Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function. | Blood 20010401 |
Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome. | Nature biotechnology 20010401 |
Protein kinase C delta regulates neural cell adhesion molecule polysialylation state in the rat brain. | Journal of neurochemistry 20010401 |
Structural and functional hot spots in cytokine receptors. | International journal of hematology 20010401 |
Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR. | Journal of molecular biology 20010330 |
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting. | The Biochemical journal 20010315 |
PhosphoSerine/threonine binding domains: you can't pSERious? | Structure (London, England : 1993) 20010307 |
Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease. | Journal of neuroscience research 20010301 |
Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding. | The EMBO journal 20010301 |
ASK1-signaling promotes c-Myc protein stability during apoptosis. | Biochemical and biophysical research communications 20010301 |
Comparison of the binuclear metalloenzymes diphosphoglycerate-independent phosphoglycerate mutase and alkaline phosphatase: their mechanism of catalysis via a phosphoserine intermediate. | Chemical reviews 20010301 |
Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription. | The Journal of biological chemistry 20010216 |
Myosin I phosphorylation is increased by chemotactic stimulation. | The Journal of biological chemistry 20010216 |
Phosphorylation of the pro-apoptotic protein BIK: mapping of phosphorylation sites and effect on apoptosis. | The Journal of biological chemistry 20010216 |
Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344, resulting in beta-arrestin- and clathrin-mediated receptor internalization. | The Journal of biological chemistry 20010216 |
3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells. | The Journal of biological chemistry 20010216 |
Phosphatidylinositol 4-phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli. | The Journal of biological chemistry 20010216 |
Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents. | FEBS letters 20010216 |
Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300. | EMBO reports 20010215 |
Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN. | Archives of biochemistry and biophysics 20010215 |
HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010201 |
Tale of a tail kinase. | Nature structural biology 20010201 |
Dopamine D(2) receptors regulate tyrosine hydroxylase activity and phosphorylation at Ser40 in rat striatum. | The European journal of neuroscience 20010201 |
Kinase suppressor of ras is necessary for tumor necrosis factor alpha activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in intestinal epithelial cells. | Cancer research 20010201 |
A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1. | Molecular cell 20010201 |
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. | Molecular cell 20010201 |
Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer. | Molecular and cellular biochemistry 20010201 |
Regulation of the ligand binding activity of the human very low density lipoprotein receptor by protein kinase C-dependent phosphorylation. | The Journal of biological chemistry 20010105 |
Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain. | Neurochemistry international 20010101 |
Novel properties of the protein kinase CK2-site-regulated nuclear- localization sequence of the interferon-induced nuclear factor IFI 16. | The Biochemical journal 20010101 |
A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody. | Journal of immunological methods 20010101 |
Ser133 phosphate-KIX interactions in the CREB-CBP complex: an ab initio molecular dynamics study. | European biophysics journal : EBJ 20010101 |
Preparation and application of antibodies to phosphoamino acid sequences. | Biopolymers 20010101 |
Theoretical models of catalytic domains of protein phosphatases 1 and 2A with Zn2+ and Mn2+ metal dications and putative bioligands in their catalytic centers. | Acta biochimica Polonica 20010101 |
New monoclonal antibodies recognizing p53 protein phosphorylated by casein kinase II at serine 392. | Folia biologica 20010101 |
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. | Proceedings of the National Academy of Sciences of the United States of America 20001024 |
The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1. | Cancer research 20000415 |
Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. | The Journal of biological chemistry 20000407 |
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. | Science (New York, N.Y.) 19971212 |
The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix. | Journal of virology 19970601 |
Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA. | Proceedings of the National Academy of Sciences of the United States of America 19960109 |
Further studies into the Boc/solid-phase synthesis of Ser(P)- and Thr(P)-containing peptides. | International journal of peptide and protein research 19941001 |
Identification of the major regulatory phosphorylation site in sucrose-phosphate synthase. | Archives of biochemistry and biophysics 19931201 |
Serine phosphorylation of protein tyrosine phosphatase (PTP1B) in HeLa cells in response to analogues of cAMP or diacylglycerol plus okadaic acid. | Molecular and cellular biochemistry 19931101 |
Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor. | Neuroreport 19930901 |
Identification of the phosphorylation sequence in the cytoplasmic tail of the varicella-zoster virus Fc receptor glycoprotein gpI. | Journal of virology 19930801 |
Efficient solution-phase synthesis of multiple O-phosphoseryl-containing peptides related to casein and statherin. | International journal of peptide and protein research 19920801 |
Phosphotyrosine as a specificity determinant for casein kinase-2, a growth related Ser/Thr-specific protein kinase. | FEBS letters 19910225 |
A human serine endopeptidase, purified with respect to activity against a peptide with phosphoserine in the P1' position, is apparently identical with prolyl endopeptidase. | The Journal of biological chemistry 19910225 |
Identification of the site on calcineurin phosphorylated by Ca2+/CaM-dependent kinase II: modification of the CaM-binding domain. | Biochemistry 19891128 |
Synthesis of phosphopeptides containing O-phosphoserine or O-phosphothreonine. | International journal of peptide and protein research 19890601 |
Substrate-specificity determinants for a membrane-bound casein kinase of lactating mammary gland. A study with synthetic peptides. | European journal of biochemistry 19881101 |
Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action. | The Journal of biological chemistry 19880925 |
Determination of the sites of cAMP-dependent phosphorylation on the nicotinic acetylcholine receptor. | The Journal of biological chemistry 19871205 |
Location of the phosphorylation site for casein kinase-2 within the amino acid sequence of ornithine decarboxylase. | Biochimica et biophysica acta 19870615 |
Studies on the methods for the determination of phosphorylation sites in highly phosphorylated peptides or proteins: phosphorylation sites of hen egg white riboflavin binding protein. | Journal of biochemistry 19861101 |
HLA-A2 antigen phosphorylation in vitro by cyclic AMP-dependent protein kinase. Sites of phosphorylation and segmentation in class i major histocompatibility complex gene structure. | The Journal of biological chemistry 19841110 |
A novel domain mediates insulin-induced proteasomal degradation of insulin receptor substrate 1 (IRS-1). | Molecular endocrinology (Baltimore, Md.) |
p38 and p42/44 MAPKs differentially regulate progesterone receptor A and B isoform stabilization. | Molecular endocrinology (Baltimore, Md.) |