2H-1-Benzopyran-2-one, 4,7-dihydroxy-3-(3-oxo-1-phenylbutyl)-
Title | Journal |
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Warfarin Metabolites in Patients Following Cardiac Valve Implantation: A Contribution of Clinical and Genetic Factors. | Cardiovascular drugs and therapy 20150601 |
Warfarin is an effective modifier of multiple UDP-glucuronosyltransferase enzymes: evaluation of its potential to alter the pharmacokinetics of zidovudine. | Journal of pharmaceutical sciences 20150101 |
Responsiveness to low-dose warfarin associated with genetic variants of VKORC1, CYP2C9, CYP2C19, and CYP4F2 in an Indonesian population. | European journal of clinical pharmacology 20130301 |
Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases. | The Journal of pharmacology and experimental therapeutics 20120101 |
Simultaneous determination of warfarin and 7-hydroxywarfarin enantiomers by high-performance liquid chromatography with ultraviolet detection. | Therapeutic drug monitoring 20110201 |
Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin. | Chemical research in toxicology 20100517 |
Effects of folic acid supplementation on the pharmacokinetics and anticoagulant effect of warfarin: an open-label, prospective study of long-term administration in adults. | Clinical therapeutics 20100201 |
Determination of plasma warfarin concentrations in Korean patients and its potential for clinical application. | The Korean journal of laboratory medicine 20091201 |
Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans. | Chemical research in toxicology 20090701 |
R(+)XK469 inhibits hydroxylation of S-warfarin by CYP2C9. | European journal of cancer (Oxford, England : 1990) 20090701 |
Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver. | Drug metabolism and pharmacokinetics 20090101 |
CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin. | Drug metabolism and disposition: the biological fate of chemicals 20081101 |
The effect of CYP2C19 genotypes on the pharmacokinetics of warfarin enantiomers. | Journal of clinical pharmacy and therapeutics 20080201 |
Simultaneous determination of warfarin enantiomers and its metabolite in human plasma by column-switching high-performance liquid chromatography with chiral separation. | Therapeutic drug monitoring 20070601 |
Synthesis and structure-activity relationships of novel warfarin derivatives. | Bioorganic & medicinal chemistry 20070315 |
Determination of warfarin enantiomers and hydroxylated metabolites in human blood plasma by liquid chromatography with achiral and chiral separation. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050425 |
Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. | British journal of clinical pharmacology 20040501 |
mRNA and protein expression of dog liver cytochromes P450 in relation to the metabolism of human CYP2C substrates. | Xenobiotica; the fate of foreign compounds in biological systems 20030301 |