Home Aminos 9,10-Bis[n,n-di-(p-tolyl)-amino]anthracene

9,10-Bis[n,n-di-(p-tolyl)-amino]anthracene

CAS No.:
177799-16-5
Catalog Number:
AG0025K0
Molecular Formula:
C42H36N2
Molecular Weight:
568.7486
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
200mg
>98.0%(HPLC)
1 week
United States
$257
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Product Description
Catalog Number:
AG0025K0
Chemical Name:
9,10-Bis[n,n-di-(p-tolyl)-amino]anthracene
CAS Number:
177799-16-5
Molecular Formula:
C42H36N2
Molecular Weight:
568.7486
MDL Number:
MFCD12022465
IUPAC Name:
9-N,9-N,10-N,10-N-tetrakis(4-methylphenyl)anthracene-9,10-diamine
InChI:
InChI=1S/C42H36N2/c1-29-13-21-33(22-14-29)43(34-23-15-30(2)16-24-34)41-37-9-5-7-11-39(37)42(40-12-8-6-10-38(40)41)44(35-25-17-31(3)18-26-35)36-27-19-32(4)20-28-36/h5-28H,1-4H3
InChI Key:
FWXNJWAXBVMBGL-UHFFFAOYSA-N
SMILES:
Cc1ccc(cc1)N(c1c2ccccc2c(c2c1cccc2)N(c1ccc(cc1)C)c1ccc(cc1)C)c1ccc(cc1)C
Properties
Complexity:
728  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
568.288g/mol
Formal Charge:
0
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
568.764g/mol
Monoisotopic Mass:
568.288g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
6.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
12.4  
Literature
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Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120101
Therapeutic value of small molecule inhibitor to plasminogen activator inhibitor-1 for lung fibrosis. American journal of respiratory cell and molecular biology 20120101
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Intravenous tissue plasminogen activator treatment for ischemic stroke in dabigatran-treated patients. Acta neurochirurgica 20120101
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Renalase, kidney function, and markers of endothelial dysfunction in renal transplant recipients. Polskie Archiwum Medycyny Wewnetrznej 20120101
[The influence of lactate Ringer solution versus hydroxyethyl starch on coagulation and fibrinolytic system in patients with septic shock]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20120101
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Effect of serum lipid levels on stroke outcome after rt-PA therapy: SAMURAI rt-PA registry. Cerebrovascular diseases (Basel, Switzerland) 20120101
Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomas. PloS one 20120101
Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression. PloS one 20120101
Intrauterine upper extremity thrombosis successfully treated with recombinant tissue plasminogen activator, enoxaparin and collagenase. Acta haematologica 20120101
Tissue plasminogen activator and plasminogen activator inhibitor 1 contribute to sonic hedgehog-induced in vitro cerebral angiogenesis. PloS one 20120101
Fibrin membrane pupillary-block glaucoma after uneventful cataract surgery treated with intracameral tissue plasminogen activator: a case report. BMC ophthalmology 20120101
Fusion of the Mycobacterium tuberculosis antigen 85A to an oligomerization domain enhances its immunogenicity in both mice and non-human primates. PloS one 20120101
Advanced glycation end products impair the migration, adhesion and secretion potentials of late endothelial progenitor cells. Cardiovascular diabetology 20120101
Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. PloS one 20120101
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Ultrasound-targeted transfection of tissue-type plasminogen activator gene carried by albumin nanoparticles to dog myocardium to prevent thrombosis after heart mechanical valve replacement. International journal of nanomedicine 20120101
Early neurological deterioration within 24 hours after intravenous rt-PA therapy for stroke patients: the Stroke Acute Management with Urgent Risk Factor Assessment and Improvement rt-PA Registry. Cerebrovascular diseases (Basel, Switzerland) 20120101
[Evaluation for antithrombotic agents by a thrombotic model in animals]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101
Targeted delivery of tissue plasminogen activator by binding to silica-coated magnetic nanoparticle. International journal of nanomedicine 20120101
Regulated proteolytic processing of Reelin through interplay of tissue plasminogen activator (tPA), ADAMTS-4, ADAMTS-5, and their modulators. PloS one 20120101
Accelerated fibrinolysis and its propagation on vascular endothelial cells by secreted and retained tPA. Journal of biomedicine & biotechnology 20120101
Matrix metalloproteinase-10 effectively reduces infarct size in experimental stroke by enhancing fibrinolysis via a thrombin-activatable fibrinolysis inhibitor-mediated mechanism. Circulation 20111220
Calculation of numbers-needed-to-treat in parallel group trials assessing ordinal outcomes: case examples from acute stroke and stroke prevention. International journal of stroke : official journal of the International Stroke Society 20111201
17β-estradiol attenuates breakdown of blood-brain barrier and hemorrhagic transformation induced by tissue plasminogen activator in cerebral ischemia. Neurobiology of disease 20111201
Spontaneous bacterial empyema in a noncirrhotic patient: an unusual scenario. The American journal of the medical sciences 20111201
Positive association of phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20111201
Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates the expression and the release of tissue plasminogen activator (tPA) in neuronal cells: involvement of tPA in the neuroprotective effect of PACAP. Journal of neurochemistry 20111201
Rapid reversal of anticoagulation prevents excessive secondary hemorrhage after thrombolysis in a thromboembolic model in rats. Stroke 20111201
Interaction of triosephosphate isomerase from Staphylococcus aureus with plasminogen. Microbiology and immunology 20111201
Carbon monoxide and nitric oxide modulate α₂-antiplasmin and plasmin activity: role of heme. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20111201
Effects of thrombolytic agents on tympanostomy tubes occluded by blood clots. Archives of otolaryngology--head & neck surgery 20111201
Non-vitrectomizing vitreous surgery and adjuvant intravitreal tissue plasminogen activator for non-recent massive premacular hemorrhage. Journal of the Chinese Medical Association : JCMA 20111201
A simple clinical and MRI scale to predict good outcome in t-PA patients. Neurological research 20111201
Superparamagnetic iron oxide nanoparticles for delivery of tissue plasminogen activator. Journal of nanoscience and nanotechnology 20111201
Structure of green-type Rubisco activase from tobacco. Nature structural & molecular biology 20111106
Enhanced production of human recombinant proteins from CHO cells grown to high densities in macroporous microcarriers. Molecular biotechnology 20111101
Fibrinolysis is down-regulated in mouse collagen-induced arthritis, but its normalization does not alleviate the course of disease. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20111101
Maspin increases extracellular plasminogen activator activity associated with corneal fibroblasts and myofibroblasts. Experimental eye research 20111101
Vitreous hemorrhage complicating intravitreal tissue plasminogen activator and pneumatic displacement of submacular hemorrhage. Retina (Philadelphia, Pa.) 20111101
Multipotent mesenchymal stromal cells increase tPA expression and concomitantly decrease PAI-1 expression in astrocytes through the sonic hedgehog signaling pathway after stroke (in vitro study). Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20111101
Clinical and MRI predictors of no early recanalization within 1 hour after tissue-type plasminogen activator administration. Stroke 20111101
Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke. Anesthesiology 20111101
[Use of intravitreal bevacizumab for the treatment of choroidal neovascularization secondary to choroidal rupture]. Archivos de la Sociedad Espanola de Oftalmologia 20111101
Treatment for submacular hemorrhage associated with neovascular age-related macular degeneration. Seminars in ophthalmology 20111101
Thromboembolic events are associated with prolonged clot lysis time in patients with permanent atrial fibrillation. Polskie Archiwum Medycyny Wewnetrznej 20111101
A novel hemostasis assay for the simultaneous measurement of coagulation and fibrinolysis. Hematology (Amsterdam, Netherlands) 20111101
[Therapeutic time window for ischemic stroke]. Rinsho shinkeigaku = Clinical neurology 20111101
Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019
Combination treatment with low-dose Niaspan and tissue plasminogen activator provides neuroprotection after embolic stroke in rats. Journal of the neurological sciences 20111015
Postoperative statin therapy attenuates the intensity of systemic inflammation and increases fibrinolysis after coronary artery bypass grafting. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20111001
Alterations of hemostatic parameters in the early development of allogeneic hematopoietic stem cell transplantation-related complications. Annals of hematology 20111001
Lytic resistance of fibrin containing red blood cells. Arteriosclerosis, thrombosis, and vascular biology 20111001
Intra-arterial adjuvant tirofiban after unsuccessful intra-arterial thrombolysis of acute ischemic stroke: preliminary experience in 16 patients. Neuroradiology 20111001
Preclinical evidence toward the use of ketamine for recombinant tissue-type plasminogen activator-mediated thrombolysis under anesthesia or sedation. Stroke 20111001
Are vasomotor symptoms associated with alterations in hemostatic and inflammatory markers? Findings from the Study of Women's Health Across the Nation. Menopause (New York, N.Y.) 20111001
Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide production. Annals of neurology 20111001
[The effects of tea polyphenols on the injury of fibrinolytic functions induced by high-methionine dietary in rats]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20111001
Exercise influences hippocampal plasticity by modulating brain-derived neurotrophic factor processing. Neuroscience 20110929
Surface-retained tPA is essential for effective fibrinolysis on vascular endothelial cells. Blood 20110915
Effect of warfarin withdrawal on thrombolytic treatment in patients with ischaemic stroke. European journal of neurology 20110901
tPA regulates pulmonary vascular activity through NMDA receptors. American journal of physiology. Lung cellular and molecular physiology 20110901
Quantitative MRI reveals the elderly ischemic brain is susceptible to increased early blood-brain barrier permeability following tissue plasminogen activator related to claudin 5 and occludin disassembly. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110901
Zinc-triggered induction of tissue plasminogen activator by brain-derived neurotrophic factor and metalloproteinases. Journal of neurochemistry 20110901
Antioxidant activities of aqueous leaf extracts of Toona sinensis on free radical-induced endothelial cell damage. Journal of ethnopharmacology 20110901
Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke. Stroke 20110901
Influence of abdominal obesity on vascular endothelial function in overweight/obese adult men. Obesity (Silver Spring, Md.) 20110901
tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK. Neurological research 20110901
[Thrombolysis for acute ischemic stroke with recombinant tissue plasminogen activator in a Chilean public hospital]. Revista medica de Chile 20110901
Admission hyperglycemia and serial infarct volume after t-PA therapy in patients with and without early recanalization. Journal of the neurological sciences 20110815
Profibrinolytic, antithrombotic, and antiinflammatory effects of an insulin-sensitizing strategy in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial. Circulation 20110809
Profibrinolytic effect of Enzamin, an extract of metabolic products from Bacillus subtilis AK and Lactobacillus. Journal of thrombosis and thrombolysis 20110801
Pneumatic displacement of submacular hemorrhage with or without tissue plasminogen activator. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20110801
Prevention of stroke following transient ischemic attack. Current atherosclerosis reports 20110801
Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage. Journal of hypertension 20110801
Elevated levels of PAI-1 activity and t-PA antigen are associated with newly diagnosed abnormal glucose regulation in patients with ST-elevation myocardial infarction. Journal of thrombosis and haemostasis : JTH 20110801
Subtherapeutic international normalized ratio in warfarin-treated patients increases the risk for symptomatic intracerebral hemorrhage after intravenous thrombolysis. Stroke 20110801
Antibodies preventing the interaction of tissue-type plasminogen activator with N-methyl-D-aspartate receptors reduce stroke damages and extend the therapeutic window of thrombolysis. Stroke 20110801
Successful microbubble sonothrombolysis without tissue-type plasminogen activator in a rabbit model of acute ischemic stroke. Stroke 20110801
Ultrasound-enhanced rt-PA thrombolysis in an ex vivo porcine carotid artery model. Ultrasound in medicine & biology 20110801
Statistical aspects of the TNK-S2B trial of tenecteplase versus alteplase in acute ischemic stroke: an efficient, dose-adaptive, seamless phase II/III design. Clinical trials (London, England) 20110801
Collateral flow averts hemorrhagic transformation after endovascular therapy for acute ischemic stroke. Stroke 20110801
Iodinated contrast media and cerebral hemorrhage after intravenous thrombolysis. Stroke 20110801
Efficacy of intravenous tissue-type plasminogen activator in central retinal artery occlusion: report from a randomized, controlled trial. Stroke 20110801
A high admission syndecan-1 level, a marker of endothelial glycocalyx degradation, is associated with inflammation, protein C depletion, fibrinolysis, and increased mortality in trauma patients. Annals of surgery 20110801
Endosulfan-induced lipid peroxidation in rat brain and its effect on t-PA and PAI-1: ameliorating effect of vitamins C and E. The Journal of toxicological sciences 20110801
Patient outcomes from symptomatic intracerebral hemorrhage after stroke thrombolysis. Neurology 20110726
The expression of annexin II and its role in the fibrinolytic activity in acute promyelocytic leukemia. Leukemia research 20110701
Induction of the fibrinolytic system by cartilage extract mediates its antiangiogenic effect in mouse glioma. Microvascular research 20110701
Regulation of tissue plasminogen activator/plasminogen activator inhibitor-1 by hydrocortisone in rat primary astrocytes. Journal of neuroscience research 20110701
Asymmetric dimethylarginine impairs fibrinolytic activity in human umbilical vein endothelial cells via p38 MAPK and NF-κB pathways. Thrombosis research 20110701
Antithrombotic and profibrinolytic activities of phloroglucinol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701
Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation. Laboratory investigation; a journal of technical methods and pathology 20110701
Neuroprotective mechanisms of SMTP-7 in cerebral infarction model in mice. Naunyn-Schmiedeberg's archives of pharmacology 20110701
Thrombolysis treatment for submassive pulmonary thromboembolism in patients with cancer: a safe therapeutic tool. Clinics (Sao Paulo, Brazil) 20110701
The anti-fibrinolytic SERPIN, plasminogen activator inhibitor 1 (PAI-1), is targeted to and released from catecholamine storage vesicles. Blood 20110630
HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator. Journal of cell science 20110615
Acute myocardial infarction during thrombolysis of mechanical aortic valve thrombosis associated with heparin-induced thrombocytopenia. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20110601
Epigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells. Cardiovascular research 20110601
Intravenous thrombolytic treatment in a patient with transient ischemic attack associated with mural carotid thrombi. Clinical neurology and neurosurgery 20110601
Acute iliofemoral venous thrombosis in patients with atresia of the inferior vena cava can be treated successfully with catheter-directed thrombolysis. Journal of vascular and interventional radiology : JVIR 20110601
Thrombin mutant W215A/E217A treatment improves neurological outcome and reduces cerebral infarct size in a mouse model of ischemic stroke. Stroke 20110601
Soluble expression of active recombinant human tissue plasminogen activator derivative (K2S) in Escherichia coli. Pharmaceutical biology 20110601
N-acetyl-l-cysteine decreases intra-abdominal adhesion formation through the upregulation of peritoneal fibrinolytic activity and antioxidant defenses. Surgery 20110601
Interaction study between rtPA and bevacizumab. The British journal of ophthalmology 20110501
Hindered dissolution of fibrin formed under mechanical stress. Journal of thrombosis and haemostasis : JTH 20110501
Tissue plasminogen activator-containing polyurethane surfaces for fibrinolytic activity. Acta biomaterialia 20110501
Translational stroke research of the combination of thrombolysis and antioxidant therapy. Stroke 20110501
A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events. Journal of cell science 20110501
A comparative study of monosaccharide composition analysis as a carbohydrate test for biopharmaceuticals. Biologicals : journal of the International Association of Biological Standardization 20110501
[Future neuroprotective strategies in the post-thrombolysis era--neurovascular unit protection and vascular endothelial protection]. Rinsho shinkeigaku = Clinical neurology 20110501
The antidepressive effect of the physical exercise correlates with increased levels of mature BDNF, and proBDNF proteolytic cleavage-related genes, p11 and tPA. Neuroscience 20110428
Role of tissue plasminogen activator and plasminogen activator inhibitor polymorphism in myocardial infarction. Molecular biology reports 20110401
Fibrinolysis and insulin sensitivity in imidapril and candesartan (FISIC study) recipients with hypertension. Hypertension research : official journal of the Japanese Society of Hypertension 20110401
Antiangiogenic kringles derived from human plasminogen and apolipoprotein(a) inhibit fibrinolysis through a mechanism that requires a functional lysine-binding site. Biological chemistry 20110401
Novel role of platelets in mediating inflammatory responses and ventricular rupture or remodeling following myocardial infarction. Arteriosclerosis, thrombosis, and vascular biology 20110401
Angiotensin-converting enzyme inhibition and fibrinolytic balance. Hypertension research : official journal of the Japanese Society of Hypertension 20110401
Effect of in-vitro addition of sulfated xylans, glucosans or chondroitins on the prothrombin time of human plasma and on the enhancement of activation of glutamic plasminogen by tissue plasminogen activator. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110401
Subtherapeutic warfarin is not associated with increased hemorrhage rates in ischemic strokes treated with tissue plasminogen activator. Stroke 20110401
In vitro stability and compatibility of tenecteplase in central venous access devices. Hemodialysis international. International Symposium on Home Hemodialysis 20110401
Ischaemic stroke management by emergency care physicians at public sector hospitals of Karachi, Pakistan. JPMA. The Journal of the Pakistan Medical Association 20110401
Tissue plasminogen activator and plasminogen activator inhibitor-1 levels in patients with acute paraquat intoxication. Journal of Korean medical science 20110401
Effect of coffee extracts on plasma fibrinolysis and platelet aggregation. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 20110401
[Effects of metformin therapy on markers of coagulation disorders in hyperinsulinemic women with polycystic ovary syndrome]. Ginekologia polska 20110401
Diagnosis and management of transient ischaemic attack and ischaemic stroke in the acute phase. BMJ (Clinical research ed.) 20110331
Cloning and expression of truncated form of tissue plasminogen activator in Leishmania tarentolae. Biotechnology letters 20110301
The role of fibrinolysis in the era of primary percutaneous coronary intervention. Thrombosis and haemostasis 20110301
Microbubbles improve sonothrombolysis in vitro and decrease hemorrhage in vivo in a rabbit stroke model. Investigative radiology 20110301
Markers of fibrinolysis as predictors for maintenance of sinus rhythm after electrical cardioversion. Thrombosis research 20110301
Primary percutaneous coronary intervention of an unprotected left main using mini-crush drug-eluting stents facilitated by intracoronary reteplase. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
Thrombolysis for artery occlusion. Ophthalmology 20110301
tPA contributes to impairment of ATP and Ca sensitive K channel mediated cerebrovasodilation after hypoxia/ischemia through upregulation of ERK MAPK. Brain research 20110227
Induction of miR-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells: biological correlates and molecular targets. The Journal of biological chemistry 20110204
Hemostatic function of buffy coat platelets in additive solution treated with pathogen reduction technology. Transfusion 20110201
Gingival crevicular fluid IL-6, tPA, PAI-2, albumin levels following initial periodontal treatment in chronic periodontitis patients with or without type 2 diabetes. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110201
Neuroprotective effect of neuroserpin in rat primary cortical cultures after oxygen and glucose deprivation and tPA. Neurochemistry international 20110201
In vitro effects of detergent sclerosants on clot formation and fibrinolysis. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20110201
Biphasic regulation of tissue plasminogen activator activity in ischemic rat brain and in cultured neural cells: essential role of astrocyte-derived plasminogen activator inhibitor-1. Neurochemistry international 20110201
Study of the efficacy of intravenous tissue plasminogen activator in central retinal artery occlusion. International journal of stroke : official journal of the International Stroke Society 20110201
Outcomes of Thai patients with acute ischemic stroke after intravenous thrombolysis. Journal of the neurological sciences 20110115
Adenosine potentiates human lung mast cell tissue plasminogen activator activity. Journal of immunology (Baltimore, Md. : 1950) 20110115
A controlled trial of a prostacyclin and rt-PA in the treatment of severe frostbite. The New England journal of medicine 20110113
Highly potent fibrinolytic serine protease from Streptomyces. Enzyme and microbial technology 20110105
Simultaneous intravitreal injection of triamcinolone acetonide and tissue plasminogen activator for central retinal vein occlusion: a pilot study. The British journal of ophthalmology 20110101
Thrombolytic therapy for acute stroke in the elderly: an emergent condition in developing countries. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20110101
Point-of-care testing for coagulation studies in a stroke protocol: a time-saving innovation. The American journal of emergency medicine 20110101
Pneumatic displacement of acute submacular hemorrhage with and without the use of tPA. European journal of ophthalmology 20110101
Vascular protection and restorative therapy in ischemic stroke. Cell transplantation 20110101
Six-month echocardiographic study in patients with submassive pulmonary embolism and right ventricle dysfunction: comparison of thrombolysis with heparin. The American journal of the medical sciences 20110101
Primary angioplasty vs. fibrinolysis in very old patients with acute myocardial infarction: TRIANA (TRatamiento del Infarto Agudo de miocardio eN Ancianos) randomized trial and pooled analysis with previous studies. European heart journal 20110101
Characteristics and outcome of ischemic stroke patients who are free of symptoms at 24 hours following thrombolysis. Cerebrovascular diseases (Basel, Switzerland) 20110101
Evaluation and treatment of neonatal thrombus formation in 17 patients. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20110101
Von Willebrand factor and fibrinolytic parameters during the desmopressin test in patients with Cushing's disease. British journal of clinical pharmacology 20110101
Carbon monoxide releasing molecule-2 enhances coagulation and attenuates fibrinolysis by two mechanisms: insights gained with colloid dilution. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110101
[Haematoma of the floor of the mouth associated to acute myocardial infarction]. Acta otorrinolaringologica espanola 20110101
Bronchoscopic findings in a child with pandemic novel H1N1 influenza A and methicillin-resistant Staphylococcus aureus. Pediatric pulmonology 20110101
Rapid neurological recovery after intravenous tissue plasminogen activator in stroke: prognostic factors and outcome. Cerebrovascular diseases (Basel, Switzerland) 20110101
Warfarin therapy does not increase risk of symptomatic intracerebral hemorrhage in eligible patients after intravenous thrombolysis. Archives of neurology 20110101
Enhancing recovery after acute ischemic stroke with donepezil as an adjuvant therapy to standard medical care: results of a phase IIA clinical trial. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20110101
Epistatic interactions in genetic regulation of t-PA and PAI-1 levels in a Ghanaian population. PloS one 20110101
Potential of immunosuppressive agents in cerebral ischaemia. The Indian journal of medical research 20110101
Tissue-type plasminogen activator depletion affects the nasal mucosa matrix reconstruction in allergic rhinitis mice. Allergologia et immunopathologia 20110101
Young women have poorer outcomes than men after stroke. Cerebrovascular diseases (Basel, Switzerland) 20110101
Validity of HAT score for predicting symptomatic intracranial hemorrhage in acute stroke patients with proximal occlusions: data from randomized trials of sonothrombolysis. Cerebrovascular diseases (Basel, Switzerland) 20110101
Association of plasminogen activator inhibitor-1 and tissue plasminogen activator with type 2 diabetes and metabolic syndrome in Malaysian subjects. Cardiovascular diabetology 20110101
Catheter-directed thrombolysis with tPA to restore renal function after iliac venous thrombosis post-renal transplantation. Annals of transplantation 20110101
The annexin A2 system and vascular homeostasis. Vascular pharmacology 20110101
Prehospital diagnosis of ST-segment elevation myocardial infarction using an 'all-posterior' 12-lead electrocardiogram. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors 20110101
Reduced rCBV ratio in perfusion-weighted MR images predicts poor outcome after thrombolysis in acute ischemic stroke. European neurology 20110101
Inhibition of reactive gliosis attenuates excitotoxicity-mediated death of retinal ganglion cells. PloS one 20110101
Failed recovery from thrombolysis is predicted by the initial diffusion weighted imaging lesion. Cerebrovascular diseases (Basel, Switzerland) 20110101
Clinical and MRI scale to predict very poor outcome in tissue plasminogen activator patients. European neurology 20110101
[Update regarding the role of biomarkers in early diagnosis of non-small cell bronchopulmonary cancer]. Pneumologia (Bucharest, Romania) 20110101
Impact of intravitreal injection of tissue plasminogen activator on full-field electroretinogram in patients with macular oedema secondary to retinal vein occlusion. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20110101
[Lornoxicam for prevention of myocardial injury during acute ST-elevation myocardial infarction]. Kardiologiia 20110101
Updates in neuro-ophthalmology. Highlights from the 37th annual meeting of the North American Neuro-Ophthalmology Society,February 5-10, 2011, Vancouver, Canada. Reviews in neurological diseases 20110101
Prehospital administration of tenecteplase for ST-segment elevation myocardial infarction in a rural EMS system. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors 20110101
JNK suppression is essential for 17β-Estradiol inhibits prostaglandin E2-Induced uPA and MMP-9 expressions and cell migration in human LoVo colon cancer cells. Journal of biomedical science 20110101
Neurohormonal activation in acute heart failure: results from VERITAS. Cardiology 20110101
Angioedema after administration of tPA for ischemic stroke: case report. Air medical journal 20110101
Serum uri acid: neuroprotection in thrombolysis. The Bergen NORSTROKE study. BMC neurology 20110101
[Phlebothrombosis and congenital thrombophilia]. Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20110101
Activity deprivation induces neuronal cell death: mediation by tissue-type plasminogen activator. PloS one 20110101
The effect of ε-aminocaproyl-S-benzyl-L-cysteine on the t-PA activity of human saliva. Advances in medical sciences 20110101
Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC. PloS one 20110101
Platelets retain high levels of active plasminogen activator inhibitor 1. PloS one 20110101
Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited. Trials 20110101
Fatal intracerebral hemorrhage associated with administration of recombinant tissue plasminogen activator in a stroke patient on treatment with dabigatran. Cerebrovascular diseases (Basel, Switzerland) 20110101
Fibrinolytic treatment of acute ischemic stroke for patients on new oral anticoagulant drugs. Cerebrovascular diseases (Basel, Switzerland) 20110101
Tissue plasminogen activator expression and barrier properties of human brain microvascular endothelial cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Craniectomy for malignant cerebral infarction: prevalence and outcomes in US hospitals. PloS one 20110101
[Atrial fibrillation in an acute stroke unit]. Bulletin de l'Academie nationale de medecine 20110101
[Insulin resistance in preeclampsia]. Akusherstvo i ginekologiia 20110101
[Diabetic retrohialoidian hemorrage--invasive minimal treatment]. Oftalmologia (Bucharest, Romania : 1990) 20110101
Regulation of airway contractility by plasminogen activators through N-methyl-D-aspartate receptor-1. American journal of respiratory cell and molecular biology 20101201
Cerebral β-amyloid detected by Pittsburgh compound B positron emission topography predisposes to recombinant tissue plasminogen activator-related hemorrhage. Annals of neurology 20101201
Edaravone: a new therapeutic approach for the treatment of acute stroke. Medical hypotheses 20101201
The use of magnetite nanoparticles for implant-assisted magnetic drug targeting in thrombolytic therapy. Biomaterials 20101201
Genistein alters coagulation gene expression in ovariectomised rats treated with phytoestrogens. Thrombosis and haemostasis 20101201
Comparison of outcomes following thrombolytic therapy among patients with prior stroke and diabetes in the Virtual International Stroke Trials Archive (VISTA). Diabetes care 20101201
Plasmin on adherent cells: from microvesiculation to apoptosis. The Biochemical journal 20101201
Functional occurrence of the interaction of tissue plasminogen activator with the NR1 Subunit of N-methyl-D-aspartate receptors during stroke. Stroke 20101201
Carbon monoxide releasing molecule-2 enhances coagulation and diminishes fibrinolytic vulnerability in plasma exposed to heparin or argatroban. Anesthesia and analgesia 20101201
Use of tissue plasminogen activator in liver transplantation from donation after cardiac death donors. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101201
Thrombolytics for cardiac arrest: case report and systematic review of controlled trials. The Annals of pharmacotherapy 20101201
Intravitreal injection of recombinant tissue plasminogen activator and pneumatic displacement of submacular haemorrhage. The Medical journal of Malaysia 20101201
The efficacy of a hyaluronate-carboxymethylcellulose bioresorbable membrane that reduces postoperative adhesions is increased by the intra-operative co-administration of a neurokinin 1 receptor antagonist in a rat model. Surgery 20101101
Cloning and expression of functional full-length human tissue plasminogen activator in Pichia pastoris. Applied biochemistry and biotechnology 20101101
Clinical and subclinical atherosclerosis in systemic sclerosis: consequences of previous corticosteroid treatment. Scandinavian journal of rheumatology 20101101
Agents that bind annexin A2 suppress ocular neovascularization. Journal of cellular physiology 20101101
Involvement of tissue plasminogen activator in stress responsivity during acute cocaine withdrawal in mice. Stress (Amsterdam, Netherlands) 20101101
The contribution of L-arginine to the neurotoxicity of recombinant tissue plasminogen activator following cerebral ischemia: a review of rtPA neurotoxicity. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20101101
Successful emergent coronary thrombolysis in a neonate with Kawasaki's disease. Pediatric cardiology 20101101
Free radical scavenger edaravone administration protects against tissue plasminogen activator induced oxidative stress and blood brain barrier damage. Current neurovascular research 20101101
Neuroserpin protects neurons from ischemia-induced plasmin-mediated cell death independently of tissue-type plasminogen activator inhibition. The American journal of pathology 20101101
Increased expression of recombinant human tissue plasminogen activator in Leishmania tarentolae. Biotechnology journal 20101101
[New options in the therapeutic management of acute ischaemic stroke. Good results with combined i. v. and i. a. lysis and mechanical thrombectomy]. Fortschritte der Neurologie-Psychiatrie 20101101
[Japanese Guidelines for the Management of Stroke 2009 : important revised points necessary for the neurologist]. Rinsho shinkeigaku = Clinical neurology 20101101
Thrombolysis for acute stroke in Australia: outcomes from the Safe Implementation of Thrombolysis in Stroke registry (2002-2008). The Medical journal of Australia 20101018
An ultrasound-responsive nano delivery system of tissue-type plasminogen activator for thrombolytic therapy. Journal of controlled release : official journal of the Controlled Release Society 20101015
Thrombin-activatable fibrinolysis inhibitor (TAFI) antigen and activity assay in patients with primary hypothyroidism. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20101001
Neurological picture. Orolingual angio-oedema after alteplase therapy in a stroke patient concurrently using angiotensin II receptor blocker. Journal of neurology, neurosurgery, and psychiatry 20101001
Endothelial regulation of eNOS, PAI-1 and t-PA by testosterone and dihydrotestosterone in vitro and in vivo. Molecular human reproduction 20101001
Comparison of the post-embolization effects of tissue-plasminogen activator and simvastatin on neurological outcome in a clinically relevant rat model of acute ischemic stroke. Brain research 20101001
In vitro effects of detergent sclerosants on fibrinolytic enzymes and inhibitors. Thrombosis research 20101001
Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding study. Stroke 20101001
tPA activates LDL receptor-related protein 1-mediated mitogenic signaling involving the p90RSK and GSK3beta pathway. The American journal of pathology 20101001
Haemostatic safety of a unique recombinant plasmin molecule lacking kringles 2-5. Thrombosis and haemostasis 20101001
Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study. Thrombosis research 20101001
Effect of general and epidural anesthesia on hemostasis and fibrinolysis in hepatic patients. Hematology (Amsterdam, Netherlands) 20101001
[Thrombolysis during cardio-pulmonary resuscitation]. Deutsche medizinische Wochenschrift (1946) 20101001
Intravitreal tissue plasminogen activator and pneumatic displacement of submacular hemorrhage. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20101001
Acute ischemic stroke therapy. Expert review of cardiovascular therapy 20101001
[Experimental study on effect of pre-acupuncture and moxibustion on molecular markers in pre-thrombosis state of rats]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20101001
A revised model for the secretion of tPA and cytokines from cultured endothelial cells. Blood 20100923
GnRH receptor and peritoneal plasmin activity. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100901
tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling. The American journal of pathology 20100901
A novel finding of a low-molecular-weight compound, SMTP-7, having thrombolytic and anti-inflammatory effects in cerebral infarction of mice. Naunyn-Schmiedeberg's archives of pharmacology 20100901
Adjunctive treatment with ticagrelor, but not clopidogrel, added to tPA enables sustained coronary artery recanalisation with recovery of myocardium perfusion in a canine coronary thrombosis model. Thrombosis and haemostasis 20100901
[Comparison of superselective intraarterial fibrinolysis with conservative therapy. Use in patients with acute non-arteritic central retinal artery occlusion]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20100901
Gingival status, crevicular fluid tissue-type plasminogen activator, plasminogen activator inhibitor-2 levels in pregnancy versus post-partum. Australian dental journal 20100901
Tissue-type plasminogen activator induces plasmin-dependent proteolysis of intracellular neuronal nitric oxide synthase. Biology of the cell 20100818
Early stroke treatment with IV t-PA associated with early recanalization. Journal of the neurological sciences 20100815
Intravenous thrombolysis in patients with stroke attributable to small artery occlusion. European journal of neurology 20100801
Measurement of carboxypeptidase U (active thrombin-activatable fibrinolysis inhibitor) in plasma: Challenges overcome by a novel selective assay. Analytical biochemistry 20100801
Ataxia with vitamin E deficiency: update of molecular diagnosis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20100801
Increased serum vWF and sVCAM-1 levels are associated with late or very late angiographic stent thrombosis after sirolimus-eluting stent implantation. Coronary artery disease 20100801
Novel plasminogen activator inhibitor-1-derived peptide protects against impairment of cerebrovasodilation after photothrombosis through inhibition of JNK MAPK. American journal of physiology. Regulatory, integrative and comparative physiology 20100801
The URICO-ICTUS study, a phase 3 study of combined treatment with uric acid and rtPA administered intravenously in acute ischaemic stroke patients within the first 4.5 h of onset of symptoms. International journal of stroke : official journal of the International Stroke Society 20100801
The effect of initial treatment of periodontitis on systemic markers of inflammation and cardiovascular risk: a randomized controlled trial. European journal of oral sciences 20100801
Levonorgestrel-intrauterine system effects on hemostasis and menstrual blood loss in women seeking contraception. The journal of obstetrics and gynaecology research 20100801
Management of thrombolysis-associated symptomatic intracerebral hemorrhage. Archives of neurology 20100801
[Chromatography-assisted refolding of a fusion protein containing multiple disulfide bonds]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20100801
Simvastatin improves clinical scores in a rabbit multiple infarct ischemic stroke model: synergism with a ROCK inhibitor but not the thrombolytic tissue plasminogen activator. Brain research 20100716
Safety of performing CT angiography in stroke patients treated with intravenous thrombolysis. Journal of neurology, neurosurgery, and psychiatry 20100701
Circulating markers of arterial thrombosis and late-stage age-related macular degeneration: a case-control study. Eye (London, England) 20100701
Construction of thrombus-targeted microbubbles carrying tissue plasminogen activator and their in vitro thrombolysis efficacy: a primary research. Journal of thrombosis and thrombolysis 20100701
Tissue plasminogen activator and plasminogen are critical for osmotic homeostasis by regulating vasopressin secretion. Journal of neuroscience research 20100701
Complications in the upper extremity following intra-arterial drug abuse. The Journal of hand surgery, European volume 20100701
Carbon monoxide releasing molecule-2 enhances coagulation and diminishes fibrinolytic vulnerability in subjects exposed to warfarin. Thrombosis research 20100701
The influence of acute resistance training and body composition on coagulation and fibrinolytic activity in low-risk women. International journal of sports medicine 20100701
Mechanism of the synergistic effect between oversulfated chondroitin-6-sulfate and lysine or 6-aminohexanoic acid in enhancing the in-vitro activation of glutamic plasminogen by tissue plasminogen activator or urokinase. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20100701
Theaflavin digallate inactivates plasminogen activator inhibitor: could tea help in Alzheimer's disease and obesity? International journal of molecular medicine 20100701
Plasma VAP-1/SSAO activity predicts intracranial hemorrhages and adverse neurological outcome after tissue plasminogen activator treatment in stroke. Stroke 20100701
Repurposing an old drug to improve the use and safety of tissue plasminogen activator for acute ischemic stroke: minocycline. Pharmacotherapy 20100701
Effects of acute insulin-induced hypoglycemia on indices of inflammation: putative mechanism for aggravating vascular disease in diabetes. Diabetes care 20100701
Central retinal artery occlusion: local intra-arterial fibrinolysis versus conservative treatment, a multicenter randomized trial. Ophthalmology 20100701
Effect of selective serotonin re-uptake inhibitors (SSRIs) on functional outcome in patients with acute ischemic stroke treated with tPA. Journal of the neurological sciences 20100615
Identification of the unpaired cysteine status and complete mapping of the 17 disulfides of recombinant tissue plasminogen activator using LC-MS with electron transfer dissociation/collision induced dissociation. Analytical chemistry 20100615
In vitro and in vivo antiangiogenic activity of a novel deca-peptide derived from human tissue-type plasminogen activator kringle 2. Biochemical and biophysical research communications 20100611
Assessment of fibrinolytic activity by measuring the lysis time of a tissue-factor-induced clot: a feasibility evaluation. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20100601
Circulating vascular endothelial growth factor in the normo- and/or microalbuminuric patients with type 2 diabetes mellitus. Acta diabetologica 20100601
Retinoids regulate human amniotic tissue-type plasminogen activator gene by a two-step mechanism. Journal of cellular and molecular medicine 20100601
Video microscope recording of the dynamic course of thrombosis and thrombolysis of the retinal vein in rabbits. Retina (Philadelphia, Pa.) 20100601
Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activator. Neurobiology of disease 20100601
Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus. The Journal of clinical investigation 20100601
Lack of association between hyperglycaemia at arrival and clinical outcomes in acute stroke patients treated with tissue plasminogen activator. International journal of stroke : official journal of the International Stroke Society 20100601
Plasma BDNF and tPA are associated with late-onset geriatric depression. Psychiatry and clinical neurosciences 20100601
Effect of Chinese herbal medicine for activating blood circulation and detoxifying on expression of inflammatory reaction and tissue damage related factors in experimental carotid artery thrombosis rats. Chinese journal of integrative medicine 20100601
Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system. Journal of biotechnology 20100517
Tissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100512
Tissue plasminogen activator antigen predicts medium-term left ventricular end-systolic volume after acute myocardial infarction. Journal of thrombosis and thrombolysis 20100501
NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity. Cell death and differentiation 20100501
A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100501
Combination treatment with VELCADE and low-dose tissue plasminogen activator provides potent neuroprotection in aged rats after embolic focal ischemia. Stroke 20100501
Symptomatic intracerebral hemorrhage among eligible warfarin-treated patients receiving intravenous tissue plasminogen activator for acute ischemic stroke. Archives of neurology 20100501
The direct thrombin inhibitors (argatroban, bivalirudin and lepirudin) and the indirect Xa-inhibitor (danaparoid) increase fibrin network porosity and thus facilitate fibrinolysis. Thrombosis and haemostasis 20100501
Effects of menstrual cycle on periodontal health and gingival crevicular fluid markers. Journal of periodontology 20100501
Combination of tissue-plasminogen activator with erythropoietin induces blood-brain barrier permeability, extracellular matrix disaggregation, and DNA fragmentation after focal cerebral ischemia in mice. Stroke 20100501
Ezetimibe therapy and its influence on oxidative stress and fibrinolytic activity. Southern medical journal 20100501
Real-time visualization of complexin during single exocytic events. Nature neuroscience 20100501
Effects of ethanol intoxication and gender on blood coagulation. The Journal of trauma 20100501
Retinal vein occlusion and low-dose fibrinolytic therapy. Retina (Philadelphia, Pa.) 20100501
[Intravenous recombinant tissue plasminogen activator in an 18-week pregnant woman with embolic stroke]. Rinsho shinkeigaku = Clinical neurology 20100501
[Case of branch atheromatous disease presenting capsular warning syndrome]. Rinsho shinkeigaku = Clinical neurology 20100501
Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice. Brain research 20100422
Early thrombin generation and impaired fibrinolysis after SCT associate with acute GVHD. Bone marrow transplantation 20100401
Effects of atenolol or losartan on fibrinolysis and von Willebrand factor in hypertensive patients with left ventricular hypertrophy. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20100401
Effects of inhalable particulate matter on blood coagulation. Journal of thrombosis and haemostasis : JTH 20100401
Enhanced fibrinolysis by proteolysed coagulation factor Xa. Biochimica et biophysica acta 20100401
Optimal brain perfusion CT coverage in patients with acute middle cerebral artery stroke. AJNR. American journal of neuroradiology 20100401
Effects of Glimepiride on metabolic parameters and cardiovascular risk factors in patients with newly diagnosed type 2 diabetes mellitus. Diabetes research and clinical practice 20100401
The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier. Journal of neurochemistry 20100401
Xenon is an inhibitor of tissue-plasminogen activator: adverse and beneficial effects in a rat model of thromboembolic stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100401
Dabigatran enhances clot susceptibility to fibrinolysis by mechanisms dependent on and independent of thrombin-activatable fibrinolysis inhibitor. Journal of thrombosis and haemostasis : JTH 20100401
A matching algorithm to address imbalances in study populations: application to the National Institute of Neurological Diseases and Stroke Recombinant Tissue Plasminogen Activator acute stroke trial. Stroke 20100401
Oxidative stress after thrombolysis-induced reperfusion in human stroke. Stroke 20100401
Therapeutic hypothermia for acute ischemic stroke. Expert review of cardiovascular therapy 20100401
[Effects of statin use on intracranial hemorrhage and clinical outcome after intravenous rt-PA for acute ischemic stroke: SAMURAI rt-PA registry]. Rinsho shinkeigaku = Clinical neurology 20100401
Fcgamma receptors contribute to pyramidal cell death in the mouse hippocampus following local kainic acid injection. Neuroscience 20100331
Endothelial progenitor populations in differentiating embryonic stem cells. II. Drug selection and functional characterization. Tissue engineering. Part A 20100301
Combination therapy of 17beta-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke. The Journal of pharmacology and experimental therapeutics 20100301
The Stroke Practice Improvement Network: a quasiexperimental trial of a multifaceted intervention to improve quality. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20100301
[Combination of Intravitreal rTPA, gas and ranibizumab for extensive subfoveal haemorrhages secondary to neovascular age-related macular degeneration]. Klinische Monatsblatter fur Augenheilkunde 20100301
Effects of hydroxysafflor yellow A on the experimental traumatic brain injury in rats. Journal of Asian natural products research 20100301
Effect of combined angiotensin-converting enzyme and aldosterone inhibition on plasma plasminogen activator inhibitor type 1 levels in chronic hypertensive patients. Nephrology (Carlton, Vic.) 20100301
[Management of subretinal hemorrhage with r-TPA, SF-6 and ranibizumab]. Archivos de la Sociedad Espanola de Oftalmologia 20100301
Effects of carvedilol or metoprolol on PAI-1, tPA-mass concentration or Von Willebrand factor in chronic heart failure--a COMET substudy. Thrombosis research 20100201
Stroke in China. Clinical and experimental pharmacology & physiology 20100201
Influence of antiplatelet pre-treatment on the risk of intracranial haemorrhage in acute ischaemic stroke after intravenous thrombolysis. European journal of neurology 20100201
Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset. Stroke 20100201
[Pars plana vitrectomy, subretinal injection of recombinant tissue plasminogen activator and fluid-gas exchange in the management of massive submacular hemorrhages secondary to age-related macular degeneration]. Journal francais d'ophtalmologie 20100201
Management of submacular haemorrhage in age-related macular degeneration with intravitreal tenecteplase. The British journal of ophthalmology 20100201
Successful intra-arterial thrombolysis beyond the accepted 6-hour time window in two young patients. Journal of the neurological sciences 20100115
Management of submacular hemorrhage with intravitreal versus subretinal injection of recombinant tissue plasminogen activator. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20100101
Endogenous nitric oxide contributes to bradykinin-stimulated glucose uptake but attenuates vascular tissue-type plasminogen activator release. The Journal of pharmacology and experimental therapeutics 20100101
Fibrinolytic effects of transparietal ultrasound associated with intravenous infusion of an ultrasound contrast agent: study of a rat model of acute cerebral stroke. Ultrasound in medicine & biology 20100101
Baseline diabetic status and admission blood glucose were poor prognostic factors in the EPITHET trial. Cerebrovascular diseases (Basel, Switzerland) 20100101
Transient ischemic attack after tissue plasminogen activator: aborted stroke or unnecessary stroke therapy? Cerebrovascular diseases (Basel, Switzerland) 20100101
DGDA, a local sequence of the kringle 2 domain, is a functional motif of the tissue-type plasminogen activator's antiangiogenic kringle domain. Biochemical and biophysical research communications 20100101
Antiplatelet therapy in combination with rt-PA thrombolysis in ischemic stroke (ARTIS): rationale and design of a randomized controlled trial. Cerebrovascular diseases (Basel, Switzerland) 20100101
Hyperfibrinolysis, uPA/suPAR system, kynurenines, and the prevalence of cardiovascular disease in patients with chronic renal failure on conservative treatment. The American journal of the medical sciences 20100101
Subretinal coapplication of recombinant tissue plasminogen activator and bevacizumab for neovascular age-related macular degeneration with submacular haemorrhage. The British journal of ophthalmology 20100101
Conditional deletion of neuronal cyclin-dependent kinase 5 in developing forebrain results in microglial activation and neurodegeneration. The American journal of pathology 20100101
Anti-thrombin therapy during warm ischemia and cold preservation prevents chronic kidney graft fibrosis in a DCD model. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100101
Pneumatic displacement of acute submacular hemorrhage with and without the use of tissue plasminogen activator. European journal of ophthalmology 20100101
Nontraumatic isolated acute thumb ischaemia. The Journal of hand surgery, European volume 20100101
Increasing tPA activity in astrocytes induced by multipotent mesenchymal stromal cells facilitate neurite outgrowth after stroke in the mouse. PloS one 20100101
A comparison of three fibrinolytic agents in prevention of intra-abdominal adhesions. Acta chirurgica Belgica 20100101
Genome response to tissue plasminogen activator in experimental ischemic stroke. BMC genomics 20100101
The evolution of transcranial laser therapy for acute ischemic stroke, including a pooled analysis of NEST-1 and NEST-2. Current cardiology reports 20100101
Clinical experience with alteplase in the management of intracardiac and major cardiac vessels thrombosis in pediatrics: a case series. Annals of Saudi medicine 20100101
Late onset of cholesterol crystal embolism after thrombolysis for cerebral infarction. Internal medicine (Tokyo, Japan) 20100101
A randomised controlled trial of antiplatelet therapy in combination with Rt-PA thrombolysis in ischemic stroke: rationale and design of the ARTIS-Trial. Trials 20100101
25-Hydroxyvitamin D and pre-clinical alterations in inflammatory and hemostatic markers: a cross sectional analysis in the 1958 British Birth Cohort. PloS one 20100101
Effects of simulated bleeding in an in vitro nasal fibroblast wound healing model. American journal of rhinology & allergy 20100101
Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation. BMC cancer 20100101
Feasibility and safety of intravenous thrombolysis in multiethnic Asian stroke patients in Singapore. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20100101
Role of tissue-type plasminogen activator in ischemic stroke. Journal of pharmacological sciences 20100101
Predictors of major neurological improvement after intravenous thrombolysis in acute ischemic stroke: a hospital-based study from south India. Neurology India 20100101
Treatment of acute ischemic stroke: awareness among general practitioners. Neurology India 20100101
Central retinal vessel blood flow after surgical treatment for central retinal vein occlusion. Retina (Philadelphia, Pa.) 20100101
Surgical outcomes after massive subretinal hemorrhage secondary to age-related macular degeneration. Retina (Philadelphia, Pa.) 20100101
Neutralisation of uPA with a monoclonal antibody reduces plasmin formation and delays skin wound healing in tPA-deficient mice. PloS one 20100101
Cardiovascular risk associated with interactions among polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems. PloS one 20100101
Does current oral antiplatelet agent or subtherapeutic anticoagulation use have an effect on tissue-plasminogen-activator-mediated recanalization rate in patients with acute ischemic stroke? Cerebrovascular diseases (Basel, Switzerland) 20100101
Intravenous thrombolysis with recombinant tissue plasminogen activator in a stroke patient treated with dabigatran. Cerebrovascular diseases (Basel, Switzerland) 20100101
Expression of a novel chimeric truncated t-PA in CHO cells based on in silico experiments. Journal of biomedicine & biotechnology 20100101
Fibrinolytic therapy for very late stent thrombosis--is it a viable option? Cardiovascular revascularization medicine : including molecular interventions 20100101
Thrombolysis in very elderly people: controlled comparison of SITS International Stroke Thrombolysis Registry and Virtual International Stroke Trials Archive. BMJ (Clinical research ed.) 20100101
Endothelial function in migraine: a cross-sectional study. BMC neurology 20100101
Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral ischemia in mice treated with tPA. PloS one 20100101
The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor simvastatin reduces thrombolytic-induced intracerebral hemorrhage in embolized rabbits. Brain research 20091215
The t-PA-encapsulated PLGA nanoparticles shelled with CS or CS-GRGD alter both permeation through and dissolving patterns of blood clots compared with t-PA solution: an in vitro thrombolysis study. Journal of biomedical materials research. Part A 20091201
Microglia and the urokinase plasminogen activator receptor/uPA system in innate brain inflammation. Glia 20091201
Akt is a direct target for myricetin to inhibit cell transformation. Molecular and cellular biochemistry 20091201
Up-regulation of osteolytic mediators in human osteosarcoma cells stimulated with nicotine. Journal of periodontal research 20091201
Role of plasminogen activation in neuronal organization and survival. Molecular and cellular neurosciences 20091201
Tissue-type plasminogen activator deficiency attenuates peritoneal fibrosis in mice. American journal of physiology. Renal physiology 20091201
Characterization of oligosaccharides in recombinant tissue plasminogen activator produced in Chinese hamster ovary cells: two decades of analytical technology development. Analytical chemistry 20091201
Clinical pearls in thrombosis and anticoagulation. Mayo Clinic proceedings 20091201
Letter by Brown and Pretorius regarding article, 'effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients'. Circulation 20091110
Prospective evaluation of right ventricular function and functional status 6 months after acute submassive pulmonary embolism: frequency of persistent or subsequent elevation in estimated pulmonary artery pressure. Chest 20091101
Prophylaxis of catheter-related bacteremia using tissue plasminogen activator-tobramycin locks. Pediatric nephrology (Berlin, Germany) 20091101
Atorvastatin extends the therapeutic window for tPA to 6 h after the onset of embolic stroke in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20091101
Sonothrombolysis for intraocular fibrin formation in an animal model. Ultrasound in medicine & biology 20091101
Tissue-type plasminogen activator prevents abscess formation but does not affect healing of bowel anastomoses and laparotomy wounds in rats with secondary peritonitis. Surgery 20091101
Safety, effectiveness, and practicality of endovascular therapy within the first 3 hours of acute ischemic stroke onset. Neurosurgery 20091101
Role of p75 neurotrophin receptor in isoflurane-mediated neuronal changes. Anesthesiology 20091101
[Repeated local thrombolysis in a patient with axillary and subclavian vein injury and thrombosis]. Vnitrni lekarstvi 20091101
Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study. Brain research 20091019
Plasmin-mediated degradation of laminin gamma-1 is critical for ethanol-induced neurodegeneration. Biological psychiatry 20091015
Erythropoietin to augment myocardial salvage induced by coronary thrombolysis in patients with ST segment elevation acute myocardial infarction. The American journal of cardiology 20091015
CHO cells adhering to nitrogen-rich plasma-polymerised ethylene exhibit high production of a specific recombinant protein. Macromolecular bioscience 20091008
NOX2 inhibition with apocynin worsens stroke outcome in aged rats. Brain research 20091006
Effects of simvastatin on cigarette smoke extract induced tissue-type plasminogen activator and plasminogen activator inhibitor-1 expression in human umbilical vein endothelial cells. Chinese medical journal 20091005
Safety and efficacy of fondaparinux as an adjunctive treatment to thrombolysis in patients with high and intermediate risk pulmonary embolism. Journal of thrombosis and thrombolysis 20091001
Successful thrombolysis of neonatal bilateral renal vein thrombosis originating in the IVC. Pediatric nephrology (Berlin, Germany) 20091001
Endogenous tissue plasminogen activator and risk of recurrent cardiac events after an acute coronary syndrome in the MIRACL study. Atherosclerosis 20091001
Urokinase activates macrophage PON2 gene transcription via the PI3K/ROS/MEK/SREBP-2 signalling cascade mediated by the PDGFR-beta. Cardiovascular research 20091001
Relationship between tissue plasminogen activator production and specific growth rate in Chinese hamster ovary cells cultured in mannose at low temperature. Biotechnology letters 20091001
Rosiglitazone alone or in combination with tissue plasminogen activator improves ischemic brain injury in an embolic model in rats. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20091001
Acute mechanical prosthetic valve thrombosis after initiating oral anticoagulation therapy. Is bridging anticoagulation with heparin required? Interactive cardiovascular and thoracic surgery 20091001
Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk. Diabetes care 20091001
The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator. Biomaterials 20091001
Regulation of intrapleural fibrinolysis by urokinase-alpha-macroglobulin complexes in tetracycline-induced pleural injury in rabbits. American journal of physiology. Lung cellular and molecular physiology 20091001
Pre admission antithrombotics are associated with improved outcomes following ischaemic stroke: a cohort from the Registry of the Canadian Stroke Network. International journal of stroke : official journal of the International Stroke Society 20091001
Tissue-type plasminogen activator-plasmin-BDNF modulate glutamate-induced phase-shifts of the mouse suprachiasmatic circadian clock in vitro. The European journal of neuroscience 20091001
[Current topics in stroke research]. Nihon rinsho. Japanese journal of clinical medicine 20091001
Enhancement effect of ethanol on lipopolysaccharide-induced procoagulant status in human umbilical endothelial cells. Soudni lekarstvi 20091001
Combined anti-platelet therapy with aspirin and clopidogrel: risk factor for thrombolysis-related intracerebral hemorrhage in acute ischemic stroke? Journal of the neurological sciences 20090915
Dynactin regulates bidirectional transport of dense-core vesicles in the axon and dendrites of cultured hippocampal neurons. Neuroscience 20090915
Vascular dysfunction in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine 20090915
Mechanistic insight into neurotoxicity of tissue plasminogen activator-induced thrombolysis products in a rat intraluminal middle cerebral artery occlusion model. Journal of neurotrauma 20090901
Multicenter randomized trial of facilitated percutaneous coronary intervention with low-dose tenecteplase in patients with acute myocardial infarction: the Athens PCI trial. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090901
Migraine and biomarkers of endothelial activation in young women. Stroke 20090901
Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potential. Stroke 20090901
Impact of metabolic syndrome on coronary patency after thrombolytic therapy for acute myocardial infarction. Coronary artery disease 20090901
Effect of ACE inhibition on the fibrinolytic system in patients requiring coronary artery bypass grafting. The Thoracic and cardiovascular surgeon 20090901
Comparison of surgical treatments for central retinal vein occlusion; RON vs. cannulation of tissue plasminogen activator into the retinal vein. Retina (Philadelphia, Pa.) 20090901
[Prospects of thrombolytic therapy for acute ischemic stroke]. Brain and nerve = Shinkei kenkyu no shinpo 20090901
Identification of cell culture conditions to control N-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells. Biotechnology and bioengineering 20090815
Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact. Brain : a journal of neurology 20090801
Na-butyrate sustains energetic states of metabolism and t-PA productivity of CHO cells. Journal of bioscience and bioengineering 20090801
Streptokinase and enoxaparin as an alternative to fibrin-specific lytic-based regimens: an ExTRACT-TIMI 25 analysis. Drugs 20090730
Plasminogen activator inhibitor type 1 derived peptide, EEIIMD, diminishes cortical infarct but fails to improve neurological function in aged rats following middle cerebral artery occlusion. Brain research 20090724
Timing, causes, and predictors of death after three years' follow-up in the Danish Multicenter Randomized Study of Fibrinolysis versus Primary Angioplasty in Acute Myocardial Infarction (DANAMI-2) trial. The American journal of cardiology 20090715
Discreplasminin, a plasmin inhibitor isolated from Tityus discrepans scorpion venom. Archives of toxicology 20090701
Stem cells downregulate the elevated levels of tissue plasminogen activator in rats after spinal cord injury. Neurochemical research 20090701
Changes in plasma C-reactive protein and hemostatic factors prior to and after a first myocardial infarction with a median follow-up time of 8 years. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20090701
Anosognosia for right hemiplegia from dominant anterior cerebral artery stroke. Journal of the American Geriatrics Society 20090701
[Pulseless arrest in an elderly patient treated with intravenous tissue plasminogen activator for cardioembolic ischemic stroke]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20090701
Management of extensive subfoveal haemorrhage secondary to neovascular age-related macular degeneration. Eye (London, England) 20090601
A porcine model of massive, totally occlusive, pulmonary embolism. Thrombosis research 20090601
Tissue factor-expressing monocytes inhibit fibrinolysis through a TAFI-mediated mechanism, and make clots resistant to heparins. Haematologica 20090601
Intravenous tissue plasminogen activator in central retinal artery occlusion. American journal of ophthalmology 20090601
Images in neurology. Scattered cerebral microbleeds due to cardiac myxoma. Archives of neurology 20090601
[Local intra-arterial fibrinolysis in a single-eyed patient with acute occlusion of the central retinal artery]. Journal francais d'ophtalmologie 20090601
[Thrombolytic therapy for acute ischemic stroke. Experience of SITS (Safe Implementation of Thrombolysis in Stroke) register]. Neurologia (Barcelona, Spain) 20090601
Inhibitory effect on LPS-induced retinal microglial activation of downregulation of t-PA expression by siRNA interference. Current eye research 20090601
Model-based cost-effectiveness analyses for the treatment of acute stroke events: a review and summary of challenges. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090601
[An angiographic trial to evaluate the efficacy and safety of tenecteplase in Chinese patients with acute myocardial infarction]. Zhonghua xin xue guan bing za zhi 20090601
Haemostatic factors in women with history of preeclampsia. Thrombosis research 20090501
Plasma homocysteine level and left ventricular thrombus formation in acute anterior myocardial infarction patients following thrombolytic therapy with t-PA. Thrombosis research 20090501
Thrombolytic therapy in central retinal artery occlusion: cutting edge therapy, standard of care therapy, or impractical therapy? Current opinion in ophthalmology 20090501
The intranigral injection of tissue plasminogen activator induced blood-brain barrier disruption, inflammatory process and degeneration of the dopaminergic system of the rat. Neurotoxicology 20090501
Human neuroserpin: structure and time-dependent inhibition. Journal of molecular biology 20090424
The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability. Journal of molecular biology 20090424
An interesting case with prosthetic valve thrombosis. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20090410
Early initiation of low-dose atorvastatin treatment after an acute ST-elevated myocardial infarction, decreases inflammatory process and prevents endothelial injury and activation. International journal of cardiology 20090403
Empty microcatheter technique for the deployment of a self-expanding stent to treat refractory middle cerebral artery occlusion in the setting of severe proximal tortuosity. Journal of neuroimaging : official journal of the American Society of Neuroimaging 20090401
Admission hyperglycemia predicts a worse outcome in stroke patients treated with intravenous thrombolysis. Diabetes care 20090401
Dissociation and protection of the neurovascular unit after thrombolysis and reperfusion in ischemic rat brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090401
Reduced plasma fibrinolytic capacity as a potential risk factor for a first myocardial infarction in young men. British journal of haematology 20090401
Argatroban and catheter-directed thrombolysis with alteplase for limb- and graft-threatening thromboses in a patient with a history of HIT. American journal of hematology 20090401
Between Clotho and Lachesis: how isoflurane seals neuronal fate. Anesthesiology 20090401
Advanced glycation end products regulate extracellular matrix protein and protease expression by human glomerular mesangial cells. International journal of molecular medicine 20090401
Inhibition of p75 neurotrophin receptor attenuates isoflurane-mediated neuronal apoptosis in the neonatal central nervous system. Anesthesiology 20090401
[Postoperative ischemic acute stroke and thrombolytic therapy]. Annales francaises d'anesthesie et de reanimation 20090401
Serine proteases, inhibitors and receptors in renal fibrosis. Thrombosis and haemostasis 20090401
Microparticle-linked tissue factor activity and increased thrombin activity play a potential role in fibrinolysis failure in ST-segment elevation myocardial infarction. Thrombosis and haemostasis 20090401
[Search for retinal vein occlusion and tissue plasminogen activator]. Nippon Ganka Gakkai zasshi 20090401
[Intravitreal tissue plasminogen activator for treatment of central retinal vein occlusion associated with diabetic retinopathy]. Nippon Ganka Gakkai zasshi 20090401
Effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients. Circulation 20090331
Refolding and purification of rhNTA protein by chromatography. Biomedical chromatography : BMC 20090301
Antifibrinolytic agents reduce tissue plasminogen activator-mediated neuronal toxicity in vitro. Acta anaesthesiologica Scandinavica 20090301
The coagulopathy of acute promyelocytic leukaemia revisited. Best practice & research. Clinical haematology 20090301
Albumin ameliorates tissue plasminogen activator-mediated blood-brain barrier permeability and ischemic brain injury in rats. Neurological research 20090301
[Coronary flow and hemorrhagic complications after alteplase and streptokinase administration in patients with acute myocardial infarction]. Vojnosanitetski pregled 20090301
[Pharmacotherapy of stroke]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20090301
Association of variants in two vitamin e transport genes with circulating vitamin e concentrations and prostate cancer risk. Cancer research 20090215
Tacrolimus (FK506) suppresses rt-PA-induced hemorrhagic transformation in a rat thrombotic ischemia stroke model. Brain research 20090213
Effects of intravitreal gas with or without tissue plasminogen activator on submacular haemorrhage in age-related macular degeneration. Eye (London, England) 20090201
Short term effects of GnRH agonists on plasma fibrinolytic balance in patients with advanced prostate cancer. Journal of thrombosis and thrombolysis 20090201
Improving adjunctive treatment in pulmonary embolism and fibrinolytic therapy. The role of enoxaparin and weight-adjusted unfractionated heparin. Journal of thrombosis and thrombolysis 20090201
Does study enrollment delay treatment with intravenous thrombolytics for acute ischemic stroke? Stroke 20090201
Impact of oxygen supply on rtPA expression in Escherichia coli BL21 (DE3): ammonia effects. Applied microbiology and biotechnology 20090201
Matrix proteins of basement membrane of intrahepatic bile ducts are degraded in congenital hepatic fibrosis and Caroli's disease. The Journal of pathology 20090201
Laser Doppler flowmetry predicts occlusion but not tPA-mediated reperfusion success after rat embolic stroke. Experimental neurology 20090201
Can comprehensive stroke centers erase the 'weekend effect'? Cerebrovascular diseases (Basel, Switzerland) 20090201
Short-term effects of two continuous combined oestrogen-progestogen therapies on several cardiovascular risk markers in healthy postmenopausal women: a randomised controlled trial. European journal of obstetrics, gynecology, and reproductive biology 20090201
Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Stroke 20090201
The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brain. The American journal of pathology 20090201
Essential thrombocythemia: a case of acute ST-segment elevation myocardial infarction in a young female. Clinical cardiology 20090201
Reduction of postsurgical adhesions in a rat model: a comparative study. Clinics (Sao Paulo, Brazil) 20090201
Safety and dose-escalation study design of Transcranial Ultrasound in Clinical SONolysis for acute ischemic stroke: the TUCSON Trial. International journal of stroke : official journal of the International Stroke Society 20090201
Monitoring of functional plasminogen in the blood of patients on fibrinolytics. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20090101
Influence of smoking during pregnancy on haemostasis in healthy full term neonates. Thrombosis research 20090101
Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots. Thrombosis research 20090101
A thrombus stuck in the ostium of the coronary artery. European heart journal 20090101
Prostaglandin E2 acts via multiple receptors to regulate plasminogen-dependent proteolysis in the primate periovulatory follicle. Endocrinology 20090101
The presence of a right-to-left shunt is associated with dramatic improvement after thrombolytic therapy in patients with acute ischemic stroke. Stroke 20090101
The lipophilic multifunctional antioxidant edaravone (radicut) improves behavior following embolic strokes in rabbits: a combination therapy study with tissue plasminogen activator. Experimental neurology 20090101
Impact of the approval of intravenous recombinant tissue plasminogen activator therapy on the processes of acute stroke management in Japan: the Stroke Unit Multicenter Observational (SUMO) Study. Stroke 20090101
Residual flow at the site of intracranial occlusion on transcranial Doppler predicts response to intravenous thrombolysis: a multi-center study. Cerebrovascular diseases (Basel, Switzerland) 20090101
Mass spectrometric determination of disulfide linkages in recombinant therapeutic proteins using online LC-MS with electron-transfer dissociation. Analytical chemistry 20090101
Anthrax protective antigen administered by DNA vaccination to distinct subcellular locations potentiates humoral and cellular immune responses. European journal of immunology 20090101
Norrin attenuates protease-mediated death of transformed retinal ganglion cells. Molecular vision 20090101
[Thrombolysis by intravenous tissue plasminogen activator (t-PA)--current status and future direction]. Brain and nerve = Shinkei kenkyu no shinpo 20090101
Fibrinolysis-independent role of plasmin and its activators in the haematopoietic recovery after myeloablation. Journal of cellular and molecular medicine 20090101
Effect of epsilon-aminocaproyl-S-benzyl-L-cysteine on the activity of plasminogen activators. Acta poloniae pharmaceutica 20090101
Role of pulsatile perfusion with tissue plasminogen activator in deceased donor kidneys with extensive glomerular thrombosis. Transplantation proceedings 20090101
Combined neuroprotective modalities coupled with thrombolysis in acute ischemic stroke: a pilot study of caffeinol and mild hypothermia. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20090101
[Influence of tea polyphenols on the damage of fibrinolytic system induced by homocysteine in human umbilical vein endothelial cells]. Wei sheng yan jiu = Journal of hygiene research 20090101
Protecting the health of patients at cardiovascular and cerebrovascular risk - Boehringer-Ingelheim's South African journey: from fibrinolytics (Actilyse and Metalyse) to the protective anti-hypertensive (Micardis). Cardiovascular journal of Africa 20090101
Efficacy of clopidrogel on reperfusion and high-sensitivity C-reactive protein in patients with acute myocardial infarction. Mediators of inflammation 20090101
Fluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteins. BMC biotechnology 20090101
Review of tenecteplase (TNKase) in the treatment of acute myocardial infarction. Vascular health and risk management 20090101
Safety and efficacy of alteplase in the treatment of acute ischemic stroke. Vascular health and risk management 20090101
Submacular combination treatment for management of acute, massive submacular hemorrhage in age-related macular degeneration. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20090101
Tissue plasminogen activator-assisted vitrectomy: surgical drainage of submacular hemorrhage. Developments in ophthalmology 20090101
Endogenous activated protein C predicts hemorrhagic transformation and mortality after tissue plasminogen activator treatment in stroke patients. Cerebrovascular diseases (Basel, Switzerland) 20090101
Retinal vein occlusion and low-dose fibrinolytic therapy (R.O.L.F.): a prospective, randomized, controlled multicenter study of low-dose recombinant tissue plasminogen activator versus hemodilution in retinal vein occlusion. Retina (Philadelphia, Pa.) 20090101
Combination therapy with normobaric oxygen (NBO) plus thrombolysis in experimental ischemic stroke. BMC neuroscience 20090101
In vitro sonothrombolysis with duplex ultrasound: first results using a simplified model. Cerebrovascular diseases (Basel, Switzerland) 20090101
[Tissue plasminogen activator and intravitreal gas for the treatment of Terson's syndrome: case report]. Arquivos brasileiros de oftalmologia 20090101
A secretory phospholipase A2-mediated neuroprotection and anti-apoptosis. BMC neuroscience 20090101
'Tenecteplase--the best among the equals.'. Indian heart journal 20090101
Efficacy and safety of tenecteplase in ST elevation myocardial infarction patients from the Elaxim Indian Registry. Indian heart journal 20090101
Thrombolysis during resuscitation for out-of-hospital cardiac arrest. The New England journal of medicine 20081218
Tissue plasminogen activator enhances the hypoxia/reoxygenation-induced impairment of the blood-brain barrier in a primary culture of rat brain endothelial cells. Cellular and molecular neurobiology 20081201
The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial. Stroke 20081201
Extension of the thrombolytic time window with minocycline in experimental stroke. Stroke 20081201
Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST). Stroke 20081201
Male-female differences in the genetic regulation of t-PA and PAI-1 levels in a Ghanaian population. Human genetics 20081201
Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen: a novel mechanism for lipoprotein(a)-mediated inhibition of plasminogen activation. Journal of thrombosis and haemostasis : JTH 20081201
Argatroban enhances fibrinolysis by differential inhibition of thrombin-mediated activation of thrombin activatable fibrinolysis inhibitor and factor XIII. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20081201
The hard way to acute stroke treatment. Journal of hypertension 20081201
Basic and translational research on proteinase-activated receptors: regulation of nicotine reward by the tissue plasminogen activator (tPA) - plasmin system via proteinase-activated receptor 1. Journal of pharmacological sciences 20081201
[The concentration of tissue--type plasminogen activator (t-PA) in extracts of breast cancer tissue]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20081201
Tissue plasminogen activator in the amygdala: a new role for an old protease. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20081201
[Guidelines for the general management of patients with acute ischemic stroke]. Acta neurologica Taiwanica 20081201
Activated protein C promotes neovascularization and neurogenesis in postischemic brain via protease-activated receptor 1. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081126
Images in cardiovascular medicine. Regression of thrombus and electrocardiographic changes with thrombolytic therapy in acute massive pulmonary embolism. Circulation 20081118
Facilitated PCI by combination fibrinolysis or upstream tirofiban in acute ST-segment elevation myocardial infarction: results of the Alteplase and Tirofiban in Acute Myocardial Infarction (ATAMI) trial. International journal of cardiology 20081112
Detection of ciliary body detachment with anterior segment optical coherence tomography. Acta ophthalmologica 20081101
Differential regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by the cyclic-AMP system in lipopolysaccharide-stimulated rat primary astrocytes. Neurochemical research 20081101
Progesterone and its metabolite allopregnanolone differentially regulate hemostatic proteins after traumatic brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20081101
Plasminogen activators are involved in the degradation of bone by osteoclasts. Bone 20081101
Intravenous thrombolysis with low-dose recombinant tissue plasminogen activator in central retinal artery occlusion. American journal of ophthalmology 20081101
Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function. Journal of neurochemistry 20081101
Vascular B1 kinin receptors in patients with congestive heart failure. Journal of cardiovascular pharmacology 20081101
[Dynamics and functional analysis of cytokines/proteinases with drug dependence]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20081101
[The intravitreal application of the tissue plasminogen activator in the treatment of submacular hemorrhage--a case report]. Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 20081101
[Thrombolysis in central retinal artery occlusion using alteplase]. Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 20081101
[Diagnosis and management for acute ischemic stroke]. Rinsho shinkeigaku = Clinical neurology 20081101
[Neuroprotective therapy for ischemic stroke with free radical scavenger and gene-stem cell therapy]. Rinsho shinkeigaku = Clinical neurology 20081101
Blood brain barrier (BBB) dysfunction associated with increased expression of tissue and urokinase plasminogen activators following peripheral thermal injury. Neuroscience letters 20081031
The HAT Score: a simple grading scale for predicting hemorrhage after thrombolysis. Neurology 20081028
Symptomatic intracerebral hemorrhage and recanalization after IV rt-PA: a multicenter study. Neurology 20081021
The role of tissue-type plasminogen activator system in amphetamine-induced conditional place preference extinction and reinstatement. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20081001
Experimental osteonecrosis induced by a combination of low-dose lipopolysaccharide and high-dose methylprednisolone in rabbits. Joint, bone, spine : revue du rhumatisme 20081001
Systemic thrombolysis based on CT or MRI stroke imaging. Journal of neuroimaging : official journal of the American Society of Neuroimaging 20081001
Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein induce Akt phosphorylation in the ischemic brain. Blood 20081001
Retinoids and activation of PKC induce tissue-type plasminogen activator expression and storage in human astrocytes. Journal of thrombosis and haemostasis : JTH 20081001
Synergistic effect of an endothelin type A receptor antagonist, S-0139, with rtPA on the neuroprotection after embolic stroke. Stroke 20081001
Dynamic of hyperglycemia as a predictor of stroke outcome in the ECASS-II trial. Stroke 20081001
Plasminogen activator, but not systemic antibiotic therapy, prevents abscess formation in an experimental model of secondary peritonitis. The British journal of surgery 20081001
Matrilysin (matrix metalloprotease-7) cleaves membrane-bound annexin II and enhances binding of tissue-type plasminogen activator to cancer cell surfaces. The FEBS journal 20081001
Sex-related differences in the associations between hyperleptinemia, insulin resistance and dysfibrinolysis. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20081001
[Major functional recuperation of branch retinal artery occlusion from thromboses in situ]. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20081001
Genes and molecules that can potentiate or attenuate psychostimulant dependence: relevance of data from animal models to human addiction. Annals of the New York Academy of Sciences 20081001
The gender effect in stroke thrombolysis: of CASES, controls, and treatment-effect modification. Neurology 20080930
Hemorrhagic transformation of ischemic brain tissue after t-PA thrombolysis as detected by MRI may be asymptomatic, but impair neurological recovery. Journal of the neurological sciences 20080915
Relation of cardiorespiratory fitness to inflammatory markers, fibrinolytic factors, and lipoprotein(a) in patients with type 2 diabetes mellitus. The American journal of cardiology 20080915
Images in cardiovascular medicine. A sensitive dissection: profound bradycardia complicating carotid dissection. Circulation 20080909
Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent. Ultrasound in medicine & biology 20080901
Endothelial dysfunction in haemophilia patients. Haemophilia : the official journal of the World Federation of Hemophilia 20080901
Investigation of association between plasminogen activator inhibitor type-1 (PAI-1) gene 4G/5G polymorphism frequency and plasma PAI-1 enzyme activity in patients with acute stroke. Genetic testing 20080901
Effect of oversulfation on the chemical and biological properties of chondroitin-4-sulfate. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080901
Thrombolytic-associated coagulopathy and management dilemmas: a review of two cases. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080901
Older age does not increase risk of hemorrhagic complications after intravenous and/or intra-arterial thrombolysis for acute stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20080901
Aggressive blood pressure-lowering treatment before intravenous tissue plasminogen activator therapy in acute ischemic stroke. Archives of neurology 20080901
Decrease in blood pressure after intravenous administration of urapidil during recombinant tissue plasminogen activator thrombolysis for acute ischemic stroke. Clinical therapeutics 20080901
Identification of fibronectin type I domains as amyloid-binding modules on tissue-type plasminogen activator and three homologs. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20080901
Combined treatment of acute subretinal haemorrhages with intravitreal recombined tissue plasminogen activator, expansile gas and bevacizumab: a retrospective pilot study. Acta ophthalmologica 20080801
Comparison of tissue plasminogen activator-antibiotic locks with heparin-antibiotic locks in children with catheter-related bacteraemia. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080801
Tissue-type plasminogen activator release in healthy subjects and hypertensive patients: relationship with beta-adrenergic receptors and the nitric oxide pathway. Hypertension (Dallas, Tex. : 1979) 20080801
Circadian rhythm disorder of thrombosis and thrombolysis-related gene expression in apolipoprotein E knock-out mice. International journal of molecular medicine 20080801
Proinflammatory cytokines, fibrinolytic system enzymes, and biochemical indices in children with infectious para-pneumonic effusions. The Pediatric infectious disease journal 20080801
Rosuvastatin and vascular dysfunction markers in pulmonary arterial hypertension: a placebo-controlled study. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20080801
[Massive pulmonary embolism treated with a reduced dose of alteplase in a patient with acute renal failure]. Kardiologia polska 20080801
[Enzyme activity during reteplase production phase by recombinant Pichia pastoris]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801
Disruption of tissue-type plasminogen activator gene in mice aggravated liver fibrosis. Journal of gastroenterology and hepatology 20080701
Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release. Journal of leukocyte biology 20080701
Gingival crevicular fluid PGE2, IL-1beta, t-PA, PAI-2 levels in type 2 diabetes and relationship with periodontal disease. Clinical biochemistry 20080701
Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke. Nature medicine 20080701
Intravenous thrombolysis in the emergency department for the treatment of acute ischaemic stroke. Emergency medicine journal : EMJ 20080701
Antimigratory effect of TK1-2 is mediated in part by interfering with integrin alpha2beta1. Molecular cancer therapeutics 20080701
Intraarterial thrombolysis with reteplase in acute ischaemic stroke in a Pakistani center. JPMA. The Journal of the Pakistan Medical Association 20080701
Fibrinolytic treatment in left ventricular mobile thrombi with low ejection fraction: results and follow-up of seven cases. Journal of thrombosis and thrombolysis 20080601
Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080601
Lipid profile, statin use, and outcome after intravenous thrombolysis for acute ischaemic stroke. Journal of neurology 20080601
Local intraarterial fibrinolysis administered in aliquots for the treatment of central retinal artery occlusion: the Johns Hopkins Hospital experience. Stroke 20080601
Evaluation of ketone-oxime method for developing therapeutic on-demand cleavable immunoconjugates. Bioconjugate chemistry 20080601
[Efficiency of prevention and treatment of veno-occlusive disease of the liver after allogeneic stem cell transplantation]. Ai zheng = Aizheng = Chinese journal of cancer 20080601
Antithrombotic and thrombolytic therapy for ischemic stroke: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 20080601
[Role of tissue plasminogen activator in the rewarding effect of nicotine]. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 20080601
Tissue plasminogen activator (tPA) and matrix metalloproteinases in the pathogenesis of stroke: therapeutic strategies. CNS & neurological disorders drug targets 20080601
Facilitated PCI in patients with ST-elevation myocardial infarction. The New England journal of medicine 20080522
[Changes in oxidative stress and hemostatic parameters in the course of thrombolytic therapy of pulmonary embolism]. Orvosi hetilap 20080518
Role of the endothelium in the vascular effects of the thrombin receptor (protease-activated receptor type 1) in humans. Journal of the American College of Cardiology 20080506
The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors. The Journal of biological chemistry 20080502
The Danish multicentre randomized study of fibrinolytic therapy vs. primary angioplasty in acute myocardial infarction (the DANAMI-2 trial): outcome after 3 years follow-up. European heart journal 20080501
Proteolytic cleavage of carboxypeptidase N markedly increases its antifibrinolytic activity. Journal of thrombosis and haemostasis : JTH 20080501
Tissue plasminogen activator, von Willebrand factor, and risk of type 2 diabetes in older men. Diabetes care 20080501
A pilot randomized clinical safety study of sonothrombolysis augmentation with ultrasound-activated perflutren-lipid microspheres for acute ischemic stroke. Stroke 20080501
A user's guide to the NINDS rt-PA stroke trial database. PLoS medicine 20080501
Surgical treatment of central retinal vein occlusion. Acta ophthalmologica 20080501
Novel actions of tissue-type plasminogen activator in chronic kidney disease. Frontiers in bioscience : a journal and virtual library 20080501
In vitro PAI-1 inhibitory activity of oxalamide derivatives. European journal of medicinal chemistry 20080401
Increased retinal toxicity of intravitreal tissue plasminogen activator in a central retinal vein occlusion model. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080401
Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens. Journal of neurochemistry 20080401
17Beta-estradiol increases basal but not bradykinin-stimulated release of active t-PA in young postmenopausal women. Hypertension (Dallas, Tex. : 1979) 20080401
Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease. Journal of hepatology 20080401
Interferon-gamma is a therapeutic target molecule for prevention of postoperative adhesion formation. Nature medicine 20080401
Hypercoagulability due to homocystinuria in a case of head and neck reconstruction resolved with combined systemic therapy. Plastic and reconstructive surgery 20080401
Toxic effects of recombinant tissue plasminogen activator on cultured human corneal endothelial cells. Investigative ophthalmology & visual science 20080401
Platelet (dys)function and plasma plasminogen levels in hemodialysis patients. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20080401
Time course of prothrombotic and proinflammatory substance release after intracoronary stent implantation. Thrombosis and haemostasis 20080401
Indocyanine green as useful guide for retinal vein cannulation and injection of tissue plasminogen activator in rabbits. The Tohoku journal of experimental medicine 20080401
[Orolingual angioedema as complication after rt-PA in stroke patient treated with ACE inhibitor]. Rinsho shinkeigaku = Clinical neurology 20080401
[Thrombolysis for stroke in a 93-year-old female: report of a case]. Revista medica de Chile 20080401
Overexpression of plasminogen activators in the nucleus accumbens enhances cocaine-, amphetamine- and morphine-induced reward and behavioral sensitization. Genes, brain, and behavior 20080301
PAI and TPA gene polymorphisms in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 20080301
Treatment of catheter-related bacteremia with tissue plasminogen activator antibiotic locks. Pediatric nephrology (Berlin, Germany) 20080301
Overweight Latino children and adolescents have marked endothelial dysfunction and subclinical vascular inflammation in association with excess body fat and insulin resistance. Diabetes care 20080301
Effects of colloid and crystalloid solutions on endogenous activation of fibrinolysis and resistance of polymerized fibrin to recombinant tissue plasminogen activator added ex vivo. British journal of anaesthesia 20080301
Plasminogen activator inhibitor-1 predicts coronary in-stent restenosis of drug-eluting stents. Journal of thrombosis and haemostasis : JTH 20080301
tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis. Journal of the American Society of Nephrology : JASN 20080301
Mechanisms regulating plasminogen activators in transformed retinal ganglion cells. Experimental eye research 20080301
Up-regulation of gelatinases and tissue type plasminogen activator by root canal sealers in human osteoblastic cells. Journal of endodontics 20080301
[Multiple bioimaging modalities in evaluation of an experimental osteonecrosis model induced by a combination of lipopolysaccharide and methylprednisolone]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20080301
[An experimental osteonecrosis of femoral head induced by a combination of a single low-dose lipopolysaccharide and methylprednisone]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20080301
Short-term effects of angiotensin receptor blockers on blood pressure control, and plasma inflammatory and fibrinolytic parameters in patients taking angiotensin-converting enzyme inhibitors. Journal of the renin-angiotensin-aldosterone system : JRAAS 20080301
Does impairment of renal and hepatic function influence the metabolism of thrombolytics in patients with myocardial infarction? Die Pharmazie 20080301
Effects of propyl gallate on carotid artery thrombosis and coagulation/fibrinolysis system in rats. Chinese journal of integrative medicine 20080301
Immediate angioplasty versus standard therapy with rescue angioplasty after thrombolysis in the Combined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial. Lancet (London, England) 20080216
Variations in fibrinolytic parameters and inhibin-A in pregnancy: related hypertensive disorders. Journal of thrombosis and haemostasis : JTH 20080201
Bradykinin type 2 receptor BE1 genotype influences bradykinin-dependent vasodilation during angiotensin-converting enzyme inhibition. Hypertension (Dallas, Tex. : 1979) 20080201
The relationship between cardiometabolic and hemostatic variables: influence of race. Metabolism: clinical and experimental 20080201
Impaired capacity for acute endogenous fibrinolysis in smokers is restored by ascorbic acid. Free radical biology & medicine 20080201
Tissue plasminogen activator is not involved in methamphetamine-induced neurotoxicity. Journal of pharmacological sciences 20080201
Intravitreal and subretinal injection of tissue plasminogen activator (tPA) in the treatment of experimentally created retinal vein occlusion in rabbits. Retina (Philadelphia, Pa.) 20080201
[Regulation by tissue plasminogen activator of rewarding effects of drugs of abuse]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20080201
Neuroprotection in cerebral ischemia: emphasis on the SAINT trial. Current cardiology reports 20080201
[ln-hospital mortality after ST-segment elevation myocardial infarction according to reperfusion therapy]. Revista medica de Chile 20080201
Key role of tissue plasminogen activator in neurovascular coupling. Proceedings of the National Academy of Sciences of the United States of America 20080122
tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2. Glia 20080115
Hyperfibrinolysis in alcoholic cirrhosis: relative plasminogen activator inhibitor type 1 deficiency. Thrombosis research 20080101
A case of plastic bronchitis presenting 9 years after Fontan. Pediatric cardiology 20080101
Beyond cell based models of coagulation: analyses of coagulation with clot 'lifespan' resistance-time relationships. Thrombosis research 20080101
Metabolic syndrome and endothelial fibrinolytic capacity in obese adults. American journal of physiology. Regulatory, integrative and comparative physiology 20080101
An evaluation of normal saline and taurolidine on intra-abdominal adhesion formation and peritoneal fibrinolysis. The Journal of surgical research 20080101
Mosaic serine proteases in the mammalian central nervous system. Frontiers in bioscience : a journal and virtual library 20080101
The use of the Chandler loop to examine the interaction potential of NXY-059 on the thrombolytic properties of rtPA on human thrombi in vitro. British journal of pharmacology 20080101
Tissue plasminogen activator to prevent central venous access device infections: a systematic review of central venous access catheter thrombosis, infection and thromboprophylaxis. Haemophilia : the official journal of the World Federation of Hemophilia 20080101
Cholesterol measured before stroke thrombolysis is not associated with tissue plasminogen activator-related hemorrhagic transformation. Stroke 20080101
Prediction of N-linked glycan branching patterns using artificial neural networks. Mathematical biosciences 20080101
Determinants of outcome and safety of intravenous rt-PA therapy in the very old: a clinical registry study and systematic review. Age and ageing 20080101
The effect of anticonvulsant drugs on the fibrinolytic activity of tissue plasminogen activator. Cerebrovascular diseases (Basel, Switzerland) 20080101
Oxidative stress and matrix metalloproteinase-9 in acute ischemic stroke: the Biomarker Evaluation for Antioxidant Therapies in Stroke (BEAT-Stroke) study. Stroke 20080101
Acute renal artery embolism: a case report and brief literature review. Annals of vascular surgery 20080101
Retinal endovascular lysis. Ophthalmology 20080101
Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy. Investigative ophthalmology & visual science 20080101
S35225 is a direct inhibitor of Plasminogen Activator Inhibitor type-1 activity in the blood. Thrombosis research 20080101
Effect of oversulfated chondroitin-6-sulfate or oversulfated fucoidan in the activation of glutamic plasminogen by tissue plasminogen activator: role of lysine and cyanogen bromide-fibrinogen. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080101
Postprocedure intravenous eptifibatide following intra-arterial reteplase in patients with acute ischemic stroke. Journal of neuroimaging : official journal of the American Society of Neuroimaging 20080101
Effect of plasmin, plasminogen activators and a plasmin inhibitor on bovine in vitro embryo production. Reproduction, fertility, and development 20080101
Parapneumonic pleural effusion and empyema. Respiration; international review of thoracic diseases 20080101
[Acute myocardial infarction in pregnancy of 39 week treated with fibrinolysis]. Anales de medicina interna (Madrid, Spain : 1984) 20080101
The effect of Nd:YAG laser membranotomy and intravitreal tissue plasminogen activator with gas on massive diabetic premacular hemorrhage. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20080101
The effect of physiologic derangement in patients with stroke treated with thrombolysis. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20080101
[Prehospital thrombolytic therapy with tenecteplase in patients with ST-elevation myocardial infarction]. Kardiologiia 20080101
Disodium disuccinate astaxanthin prevents carotid artery rethrombosis and ex vivo platelet activation. Pharmacology 20080101
Subretinal hemorrhages secondary to age-related macular degeneration: psychological and vision-related functional perspectives. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20080101
Developmental profile of tissue plasminogen activator in postnatal Long Evans rat visual cortex. Molecular vision 20080101
Post-vitrectomy tissue plasminogen activator injection for central retinal vein occlusion. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20080101
Clopidogrel pretreatment abolishes increase of PAI-1 after coronary stent implantation. Thrombosis research 20080101
Influence of antiplatelet pre-treatment on the risk of symptomatic intracranial haemorrhage after intravenous thrombolysis. Cerebrovascular diseases (Basel, Switzerland) 20080101
Fibrin targeting of echogenic liposomes with inactivated tissue plasminogen activator. Journal of liposome research 20080101
Can intravitreal tissue plasminogen activator and SF6 gas facilitate management of macular degeneration with photodynamic therapy? European journal of ophthalmology 20080101
Characterization of the pro-thrombotic state in CAPD patients. Renal failure 20080101
Effects of omentectomy on the peritoneal fibrinolytic system. Surgery today 20080101
[Effects of biogenic phosphates on protease-induced protein cleavage and functioning of plasminogen activators]. Bioorganicheskaia khimiia 20080101
[The in vitro cross-effects of inhibitors of renin-angiotensin and fibrinolytic systems on the key enzymes of these systems]. Bioorganicheskaia khimiia 20080101
Changes in clot lysis levels of reteplase and streptokinase following continuous wave ultrasound exposure, at ultrasound intensities following attenuation from the skull bone. BMC cardiovascular disorders 20080101
The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activator. Cerebrovascular diseases (Basel, Switzerland) 20080101
Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. PloS one 20080101
[The efficacy of alteplase in pulmonary embolism treatment]. Khirurgiia 20080101
[Alteplase in acute coronary syndromes]. Archivos de cardiologia de Mexico 20080101
A risk score to predict intracranial hemorrhage after recombinant tissue plasminogen activator for acute ischemic stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20080101
Inflammation and hemostasis biomarkers for predicting stroke in postmenopausal women: the Women's Health Initiative Observational Study. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20080101
The effect of continuous combined conjugated equine estrogen plus medroxyprogesterone acetate and tibolone on cardiovascular metabolic risk factors. Climacteric : the journal of the International Menopause Society 20080101
Molecule of the Month. PDGFR-alpha antagonist Gleevec reduces blood vessel leakage and increases the therapeutic window associated with tissue plasminogen activator stroke treatment. Current topics in medicinal chemistry 20080101
Delayed postconditioning protects against focal ischemic brain injury in rats. PloS one 20080101
[Comparative effect of streptokinase and alteplase on electrocardiogram and angiogram signs of myocardial reperfusion in ST segment elevation acute myocardial infarction]. Srpski arhiv za celokupno lekarstvo 20080101
Biological signatures of brain damage associated with high serum ferritin levels in patients with acute ischemic stroke and thrombolytic treatment. Disease markers 20080101
The plasminogen activator system and cancer. Pathophysiology of haemostasis and thrombosis 20080101
[Use of fibrinolytic agents during surgical treatment for submacular hemorrhages of various etiology]. Vestnik oftalmologii 20080101
Efficacy and safety of tenecteplase in Indian patients with ST-segment elevation myocardial infraction: a future perspetive. Indian heart journal 20080101
Efficacy and safety of tenecteplase in Indian patients with st-segment elevation myocardial infarction. Indian heart journal 20080101
Reperfusion therapy in ST-segment elevation myocardial infarction in the Veteran Administration Caribbean Healthcare System; search for improvement. Boletin de la Asociacion Medica de Puerto Rico 20080101
Nattokinase-promoted tissue plasminogen activator release from human cells. Pathophysiology of haemostasis and thrombosis 20080101
Rational design of peptide ligand for affinity chromatography of tissue-type plasminogen activator by the combination of docking and molecular dynamics simulations. Journal of chromatography. A 20071221
Coronary embolism in a patient with mitral valve prosthesis: successful management with tirofiban and half-dose tissue-type plasminogen activator. Chinese medical journal 20071220
Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial. Circulation 20071204
Evaluating the optimal timing of angiography: landmark or off the mark? Circulation 20071204
Activation of post-synaptic dopamine D₁ receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling. Journal of neurochemistry 20071201
Changes in peritoneal mesothelial cells phenotype after chronic exposure to glucose or N-acetylglucosamine. Translational research : the journal of laboratory and clinical medicine 20071201
Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A. Journal of thrombosis and haemostasis : JTH 20071201
Catheter-directed thrombolysis of acute lower extremity arterial thrombosis in a patient with heparin-induced thrombocytopenia. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201
Repeated thoracenteses affect proinflammatory cytokines, vascular endothelial growth factor, and fibrinolytic activity in pleural transudates. The American journal of the medical sciences 20071201
IL-1beta stimulates urokinase-type plasminogen activator expression and secretion in human dental pulp cells. Biomedical research (Tokyo, Japan) 20071201
Rheolytic thrombectomy in patient with massive pulmonary embolism: a case report and review of literature. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071115
The effects of polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems on plasma t-PA and PAI-1 levels are dependent on environmental context. Human genetics 20071101
The PI3K/Akt pathway mediates the neuroprotective effect of atorvastatin in extending thrombolytic therapy after embolic stroke in the rat. Arteriosclerosis, thrombosis, and vascular biology 20071101
The potential of erythropoietin for conferring cardioprotection complementing reperfusion. Coronary artery disease 20071101
Stachybotrydial selectively enhances fibrin binding and activation of Glu-plasminogen. The Journal of antibiotics 20071101
[Case report of a successful pregnancy following thrombolysis for acute myocardial infarction]. Archives des maladies du coeur et des vaisseaux 20071101
Life after SAINT. International journal of stroke : official journal of the International Stroke Society 20071101
A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator. NeuroImage 20071015
The ADP receptor P2Y(1) mediates t-PA release in pigs during cardiac ischemia. Journal of thrombosis and thrombolysis 20071001
Influences of the recombinant artificial cell adhesive proteins on the behavior of human umbilical vein endothelial cells in serum-free culture. Biologicals : journal of the International Association of Biological Standardization 20071001
Optimization of fed-batch parameters and harvest time of CHO cell cultures for a glycosylated product with multiple mechanisms of inactivation. Biotechnology and bioengineering 20071001
[Angioneurotic orolingual edema associated with the use of rt-PA following a stroke]. Der Anaesthesist 20071001
Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation. The American journal of pathology 20071001
Fibrinolysis is amplified by converting alpha-antiplasmin from a plasmin inhibitor to a substrate. Journal of thrombosis and haemostasis : JTH 20071001
A multiparameter test of clot formation and fibrinolysis for in-vitro drug screening. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20071001
Time course of platelet aggregation during thrombolytic treatment of massive pulmonary embolism. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20071001
Preliminary experience with intravenous P2Y12 platelet receptor inhibition as an adjunct to reduced-dose alteplase during acute myocardial infarction: results of the Safety, Tolerability and Effect on Patency in Acute Myocardial Infarction (STEP-AMI) angiographic trial. American heart journal 20071001
Improving depiction of benefits and harms: analyses of studies of well-known therapeutics and review of high-impact medical journals. Medical care 20071001
Associations of von Willebrand factor, fibrin D-dimer and tissue plasminogen activator with incident coronary heart disease: British Women's Heart and Health cohort study. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20071001
[Massive pulmonary embolism mimicking ST-elevation acute coronary syndrome successfully treated with hybrid therapy in a trauma patient receiving nadroparin: diagnostic and therapeutic dilemmas]. Kardiologia polska 20071001
Role of posterior vitreous detachment induced by intravitreal tissue plasminogen activator in macular edema with central retinal vein occlusion. Retina (Philadelphia, Pa.) 20071001
Modulation of serpin reaction through stabilization of transient intermediate by ligands bound to alpha-helix F. The Journal of biological chemistry 20070907
Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini. Biochemistry 20070904
Cannabis-induced coronary artery thrombosis and acute anterior myocardial infarction in a young man. International journal of cardiology 20070903
Hyperglycemia during ischemia rapidly accelerates brain damage in stroke patients treated with tPA. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070901
Expression of human tissue plasminogen activator in the trypanosomatid protozoan Leishmania tarentolae. Biotechnology and applied biochemistry 20070901
Acute myocardial infarction complicated by ventricular standstill terminated by thrombolysis and transcutaneous pacing. Resuscitation 20070901
Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells. Gut 20070901
Regulation of plasminogen activators in human thyroid follicular cells and their relationship to differentiated function. Journal of cellular physiology 20070901
Hepatic veno-occlusive disease after tranexamic acid administration in patients undergoing allogeneic hematopoietic stem cell transplantation. American journal of hematology 20070901
Peritoneal adhesion prevention with an in situ cross-linkable hyaluronan gel containing tissue-type plasminogen activator in a rabbit repeated-injury model. Biomaterials 20070901
The inflammatory cytokine oncostatin M induces PAI-1 in human vascular smooth muscle cells in vitro via PI 3-kinase and ERK1/2-dependent pathways. American journal of physiology. Heart and circulatory physiology 20070901
4G/5G polymorphism of PAI-1 gene and Alu-repeat I/D polymorphism of TPA gene in Turkish patients with polycystic ovary syndrome. Journal of assisted reproduction and genetics 20070901
Expression and localisation of extracellular matrix degrading proteases and their inhibitors during the oestrous cycle and after induced luteolysis in the bovine corpus luteum. Reproduction (Cambridge, England) 20070901
Impaired endothelial antithrombotic activity following short-term interruption of continuous subcutaneous insulin infusion in type 1 diabetic patients. Thrombosis and haemostasis 20070901
Acute aldosterone infusion enhances thrombosis development in normotensive rats. Thrombosis and haemostasis 20070901
Protective effects of ginsenoside Rb1 on human umbilical vein endothelial cells in vitro. Journal of cardiovascular pharmacology 20070901
Acute effects of glucocorticoids on endothelial fibrinolytic and vasodilator function in humans. Journal of cardiovascular pharmacology 20070901
[Effects of losartan on expressions of plasminogen activator and plasminogen activator inhibitor-1 of rat proximal tubular epithelial cells cultured with high glucose]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070901
Mechanism of high glucose induced angiotensin II production in rat vascular smooth muscle cells. Circulation research 20070831
The effect of urban air pollution on inflammation, oxidative stress, coagulation, and autonomic dysfunction in young adults. American journal of respiratory and critical care medicine 20070815
Estrogen-dependent expression of the tissue kallikrein gene (Klk1) in the mouse uterus and its implications for endometrial tissue growth. Molecular reproduction and development 20070801
Axillary catheter with intermittent boluses of local anaesthetic for ischaemic upper limb pain 18 h after failed rtPA thrombolysis. European journal of anaesthesiology 20070801
The retinal tolerance to bevacizumab in co-application with a recombinant tissue plasminogen activator. The British journal of ophthalmology 20070801
Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms. Neurobiology of disease 20070801
Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice. Journal of thrombosis and haemostasis : JTH 20070801
Hemorrhage after thrombolytic therapy for stroke: the clinically relevant number needed to harm. Stroke 20070801
Diabetes mellitus as a prothrombotic condition. Journal of internal medicine 20070801
[Traumatic submacular hemorrhage treated with rt-PA and SF6]. Archivos de la Sociedad Espanola de Oftalmologia 20070801
[A randomized multicenter trial comparing recombinant staphylokinase with recombinant tissue-type plasminogen activator in patients with acute myocardial infarction]. Zhonghua xin xue guan bing za zhi 20070801
Testosterone upregulation of tissue type plasminogen activator expression in Sertoli cells : tPA expression in Sertoli cells. Endocrine 20070801
Study of the mechanism of hemostatic effect of desmopressin. Bulletin of experimental biology and medicine 20070801
Regulation of nonproteolytic active site formation in plasminogen. Biochemistry 20070731
Mast cell stabilization reduces hemorrhage formation and mortality after administration of thrombolytics in experimental ischemic stroke. Circulation 20070724
Clinical problem-solving. A sinister development--a 35-year-old woman presented to the emergency department with a 2-day history of progressive swelling and pain in her left leg, without antecedent trauma. The New England journal of medicine 20070705
Modulation of sympathetic activity by tissue plasminogen activator is independent of plasminogen and urokinase. The Journal of pharmacology and experimental therapeutics 20070701
Activation of human platelets by misfolded proteins. Arteriosclerosis, thrombosis, and vascular biology 20070701
Intravenous thrombolysis for acute ischemic stroke after vitrectomy for retinal detachment. Stroke 20070701
A pilot study of dual treatment with recombinant tissue plasminogen activator and uric acid in acute ischemic stroke. Stroke 20070701
Acute enoxaparin treatment widens the therapeutic window for tPA in a mouse model of embolic stroke. Neurological research 20070701
Does coronary angioplasty after timely thrombolysis improve microvascular perfusion and left ventricular function after acute myocardial infarction? American heart journal 20070701
Ultrasound-enhanced thrombolysis in acute ischemic stroke: potential, failures, and safety. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070701
Silicone oil pupillary block: an exception to combined argon-Nd:YAG laser iridotomy success in angle-closure glaucoma. Archives of ophthalmology (Chicago, Ill. : 1960) 20070701
Singlet oxygen potentiates thrombolysis. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20070701
Effect of fluvastatin and valsartan, alone and in combination, on postprandial vascular inflammation and fibrinolytic activity in patients with essential hypertension. Journal of cardiovascular pharmacology 20070701
Intracellular catalysis of disulfide bond formation by the human sulfhydryl oxidase, QSOX1. The Biochemical journal 20070615
Outcomes and optimal antithrombotic therapy in women undergoing fibrinolysis for ST-elevation myocardial infarction. Circulation 20070605
Fibrinolytic properties of lysine-derivatized polyethylene in contact with flowing whole blood (Chandler loop model). Journal of biomedical materials research. Part A 20070601
Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system. Journal of neurochemistry 20070601
Postmenopausal oral estrogen therapy affects hemostatic factors, but does not account for reduction in the progression of subclinical atherosclerosis. Journal of thrombosis and haemostasis : JTH 20070601
The phenylpropanoid micronutrient chlorogenic acid improves clinical rating scores in rabbits following multiple infarct ischemic strokes: synergism with tissue plasminogen activator. Experimental neurology 20070601
Enhanced poly(ADP-ribose) polymerase-1 activation contributes to recombinant tissue plasminogen activator-induced aggravation of ischemic brain injury in vivo. Journal of neuroscience research 20070601
Combination treatment with dipyridamole, aspirin, and tPA in an embolic model of stroke in rats. Experimental neurology 20070601
Glucagon as a determinant of fibrinolytic activity in men with different stages of glucose tolerance: impact of glucagon on fibrinolysis. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070601
Non-proteolytic neurotrophic effects of tissue plasminogen activator on cultured mouse cerebrocortical neurons. Journal of neurochemistry 20070601
Effects of candesartan and lisinopril on the fibrinolytic system in hypertensive patients. Journal of clinical hypertension (Greenwich, Conn.) 20070601
Can maternal dietary intervention modify Doppler parameters of the fetoplacental circulation? American journal of obstetrics and gynecology 20070601
Effect of a cholesterol-lowering diet during pregnancy on maternal and fetal Doppler velocimetry: the CARRDIP study. American journal of obstetrics and gynecology 20070601
Treatment of mechanical valve thrombosis during pregnancy. Clinical cardiology 20070601
Role of tissue-plasminogen activator (t-PA) in a mouse model of neonatal white matter lesions: interaction with plasmin inhibitors and anti-inflammatory drugs. Neuroscience 20070511
Mechanism by which alcohol and wine polyphenols affect coronary heart disease risk. Annals of epidemiology 20070501
[Study on the mechanism of neuropsychological abnormalities induced by drugs of abuse]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070501
Combined rTPA and aspirin therapy for intracardiac thrombosis in neonates. Arquivos brasileiros de cardiologia 20070501
Diagnosis of colo-rectal cancer revealed by haemorrhagic complication of intraarterial thrombolysis. VASA. Zeitschrift fur Gefasskrankheiten 20070501
Polypoidal choroidal vasculopathy in Korean patients with large submacular hemorrhage. Yonsei medical journal 20070430
FK-506 extended the therapeutic time window for thrombolysis without increasing the risk of hemorrhagic transformation in an embolic rat stroke model. Brain research 20070427
Reinforcing effects of morphine are reduced in tissue plasminogen activator-knockout mice. Neuroscience 20070425
Tissue type plasminogen activator induced in rat dorsal horn astrocytes contributes to mechanical hypersensitivity following dorsal root injury. Glia 20070415
Microalbuminuria is a risk factor for cerebral small vessel disease in community-based elderly subjects. Journal of the neurological sciences 20070415
Novel biomimetic affinity ligands for human tissue plasminogen activator. Biochemical and biophysical research communications 20070413
Management of macular hole and submacular hemorrhage in the same eye. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070401
Retinal endovascular lysis in ischemic central retinal vein occlusion: one-year results of a pilot study. Ophthalmology 20070401
The glycocalyx protects erythrocyte-bound tissue-type plasminogen activator from enzymatic inhibition. The Journal of pharmacology and experimental therapeutics 20070401
Hyperbaric oxygen-induced attenuation of hemorrhagic transformation after experimental focal transient cerebral ischemia. Stroke 20070401
Nitric oxide modulates tissue plasminogen activator release in normotensive subjects and hypertensive patients. Hypertension (Dallas, Tex. : 1979) 20070401
Histopathological findings after retinal endovascular lysis in central retinal vein occlusion. The British journal of ophthalmology 20070401
Extracellular proteins of Lactobacillus crispatus enhance activation of human plasminogen. Microbiology (Reading, England) 20070401
Glucose-based PD solution, but not icodextrin-based PD solution, induces plasminogen activator inhibitor-1 and tissue-type plasminogen activator in human peritoneal mesothelial cells via ERK1/2. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20070401
Inhibition of plasminogen activators attenuates the death of differentiated retinal ganglion cells and stabilizes their neurite network in vitro. Investigative ophthalmology & visual science 20070401
Haemostatic activation in post-menopausal women taking low-dose hormone therapy: less effect with transdermal administration? Thrombosis and haemostasis 20070401
Ethnic differences in cardiovascular risk factors in healthy Caucasian and South Asian individuals with the metabolic syndrome. Journal of thrombosis and haemostasis : JTH 20070401
Failure to improve the effect of thrombolysis by memantine in a rat embolic stroke model. Neurological research 20070401
[Can dexpanthenol prevent peritoneal adhesion formation? An experimental study]. Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20070401
Cloning and expression of a human tissue plasminogen activator variant: K2S in Escherichia coli. Pakistan journal of biological sciences : PJBS 20070315
Sex as a predictor of outcomes in patients treated with thrombolysis for acute stroke. Neurology 20070313
Comment re: multicenter study of the European Assessment Group for Lysis in the Eye (EAGLE) for the treatment of central retinal artery occlusion: design issues and implications. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070301
Possible role of the plasminogen activation system in human subfertility. Fertility and sterility 20070301
Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: comparison with tissue plasminogen activator. Experimental neurology 20070301
Characterization of the hepatic disposition of lanoteplase, a rationally designed variant of tissue plasminogen activator in rodents. Drug metabolism and disposition: the biological fate of chemicals 20070301
Increased plasminogen activator inhibitor-1/tissue type plasminogen activator ratio in oral submucous fibrosis. Oral diseases 20070301
Imaging of pulmonary embolism and t-PA therapy effects using MDCT and liposomal iohexol blood pool agent: preliminary results in a rabbit model. Academic radiology 20070301
Expression of the serine protease inhibitor neuroserpin in cells of the human myeloid lineage. Thrombosis and haemostasis 20070301
The effectiveness of a single intraperitoneal infusion of a neurokinin-1 receptor antagonist in reducing postoperative adhesion formation is time dependent. Surgery 20070301
Management of submacular hemorrhage with intravitreal injection of tissue plasminogen activator and expansile gas. Retina (Philadelphia, Pa.) 20070301
Identification of a novel targeting sequence for regulated secretion in the serine protease inhibitor neuroserpin. The Biochemical journal 20070215
Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory. Journal of cell science 20070215
Pars plana vitrectomy with peripheral retinotomy after injection of preoperative intravitreal tissue plasminogen activator: a modified procedure to drain massive subretinal haemorrhage. The British journal of ophthalmology 20070201
Gender-specific correlations of plasminogen activator inhibitor-1 and tissue plasminogen activator levels with cardiovascular disease-related traits. Journal of thrombosis and haemostasis : JTH 20070201
Antiproliferative agents alter vascular plasminogen activator inhibitor-1 expression: a potential prothrombotic mechanism of drug-eluting stents. Arteriosclerosis, thrombosis, and vascular biology 20070201
Emerging thrombotic effects of drug eluting stents. Arteriosclerosis, thrombosis, and vascular biology 20070201
The antifertility effectiveness of copper/low-density polyethylene nanocomposite and its influence on the endometrial environment in rats. Contraception 20070201
Statins (HMG-CoA reductase inhibitors) decrease postoperative adhesions by increasing peritoneal fibrinolytic activity. Annals of surgery 20070201
The use of statins in postoperative adhesion prevention. Annals of surgery 20070201
Lack of experience of intravenous thrombolysis for acute ischaemic stroke does not influence the proportion of patients treated. Emergency medicine journal : EMJ 20070201
Paget-Schroetter syndrome treated with thrombolytics and immediate surgery. Journal of vascular surgery 20070201
Acute tissue-type plasminogen activator release in human microvascular endothelial cells: the roles of Galphaq, PLC-beta, IP3 and 5,6-epoxyeicosatrienoic acid. Thrombosis and haemostasis 20070201
Drug-induced thrombosis--experimental, clinical, and mechanistic considerations. Toxicologic pathology 20070201
Addition of intravenous N-methyl-D-aspartate receptor antagonists to local fibrinolytic therapy for the optimal treatment of experimental intracerebral hemorrhages. Journal of neurosurgery 20070201
Established treatments for acute ischaemic stroke. Lancet (London, England) 20070127
Stress-induced spine loss in the medial amygdala is mediated by tissue-plasminogen activator. Neuroscience 20070105
Uric acid reduces brain damage and improves the benefits of rt-PA in a rat model of thromboembolic stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070101
The logistic transform for bounded outcome scores. Biostatistics (Oxford, England) 20070101
Mild hyperhomocysteinemia is associated with a decreased fibrinolytic activity in patients after ST-elevation myocardial infarction. Thrombosis research 20070101
The effect of primary percutaneous coronary intervention as compared to tenecteplase on myeloperoxidase, pregnancy-associated plasma protein A, soluble fibrin and D-dimer in acute myocardial infarction. Thrombosis research 20070101
Aryl hydrocarbon receptor activation impairs extracellular matrix remodeling during zebra fish fin regeneration. Toxicological sciences : an official journal of the Society of Toxicology 20070101
Homocysteine reduction by B-vitamin supplementation increases t-PA and PAI-1 levels in patients with venous thromboembolism. Journal of thrombosis and haemostasis : JTH 20070101
Salmeterol enhances pulmonary fibrinolysis in healthy volunteers. Critical care medicine 20070101
Statins may enhance the proteolytic cleavage of proBDNF: implications for the treatment of depression. Medical hypotheses 20070101
Frequency and predictors of symptomatic intracerebral hemorrhage in patients with ischemic stroke treated with recombinant tissue plasminogen activator outside clinical trials. Cerebrovascular diseases (Basel, Switzerland) 20070101
Asymptomatic hemorrhage after thrombolysis may not be benign: prognosis by hemorrhage type in the Canadian alteplase for stroke effectiveness study registry. Stroke 20070101
Serum levels of vitamin D and haemostatic factors in healthy subjects: the Tromsø study. Acta haematologica 20070101
Activation of blood coagulation in patients with major depressive disorder during euglycemic hyperinsulinemia. Thrombosis research 20070101
Epsilon-aminocaproic acid inhibition of fibrinolysis in vitro: should the 'therapeutic' concentration be reconsidered? Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070101
Photoreceptor status after resolved macular edema in branch retinal vein occlusion treated with tissue plasminogen activator. American journal of ophthalmology 20070101
Urokinase separation from cell culture broth of a human kidney cell line. International journal of biological sciences 20070101
Clot structure modification by fondaparinux and consequence on fibrinolysis: a new mechanism of antithrombotic activity. Thrombosis and haemostasis 20070101
Catheter lock heparin concentration: effects on tissue plasminogen activator use in tunneled cuffed catheters. Hemodialysis international. International Symposium on Home Hemodialysis 20070101
EGF increases expression and activity of PAs in preimplantation rat embryos and their implantation rate. Reproductive biology and endocrinology : RB&E 20070101
Spotlight on reteplase in thrombotic occlusive disorders. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20070101
Insight into the profibrinolytic activity of dermatan sulfate: effects on the activation of plasminogen mediated by tissue and urinary plasminogen activators. Thrombosis research 20070101
The role of simvastatin on postoperative peritoneal adhesion formation in an animal model. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20070101
The mechanism of 3-methoxy puerarin on decreasing the cerebral ischemia-reperfusion injury in rats. Asia Pacific journal of clinical nutrition 20070101
Significance of microvascular thrombosis in renal allografts: role of ex vivo thrombolytic therapy. Clinical transplantation 20070101
Acute stroke: we have the treatments and we have the evidence--we need to use them. Critical care (London, England) 20070101
Aphasia: associated disturbances in affect, behavior, and cognition in the setting of speech and language difficulties. Psychosomatics 20070101
Insights into the change in brain natriuretic peptide after ST-elevation myocardial infarction (STEMI): why should it be better than baseline? Canadian journal of physiology and pharmacology 20070101
[Massive pulmonary embolism, thrombus in transit, and right ventricular dysfunction]. Archivos de cardiologia de Mexico 20070101
Symptomatic intracerebral hemorrhage following thrombolytic therapy for acute ischemic stroke: a review of the risk factors. Cerebrovascular diseases (Basel, Switzerland) 20070101
The role of vitrectomy assisted rt-PA injection for the management of branch retinal vein occlusion: case report. Seminars in ophthalmology 20070101
Cerebral venous congestion as indication for thrombolytic treatment. Cardiovascular and interventional radiology 20070101
Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis. BMC immunology 20070101
Preliminary experience with intra-arterial nicardipine in patients with acute ischemic stroke. Neurocritical care 20070101
Feasibility of IA thrombolysis for acute ischemic stroke among anticoagulated patients. Neurocritical care 20070101
Predictors for recanalization after intravenous thrombolysis in acute ischemic stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20070101
Association of PAI-1 4G/5G and -844G/A gene polymorphism and changes in PAI-1/tPA levels in stroke: a case-control study. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20070101
The PAI-1 4G/5G gene polymorphism and ischemic stroke: an association study and meta-analysis. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20070101
[Dehydroepiandrosterone therapy in men with angiographically verified coronary heart disease: the effects on plasminogen activator inhibitor-1 (PAI-1), tissue plasminogen activator (tPA) and fibrinogen plasma concentrations]. Endokrynologia Polska 20070101
Cell separator operation within temperature ranges to minimize effects on Chinese hamster ovary cell perfusion culture. Biotechnology progress 20070101
A population-based study in Ghana to investigate inter-individual variation in plasma t-PA and PAI-1. Ethnicity & disease 20070101
Intrapleural low-molecular-weight urokinase or tissue plasminogen activator versus single-chain urokinase in tetracycline-induced pleural loculation in rabbits. Experimental lung research 20070101
Effects of nateglinide and glibenclamide on prothrombotic factors in naïve type 2 diabetic patients treated with metformin: a 1-year, double-blind, randomized clinical trial. Internal medicine (Tokyo, Japan) 20070101
Reperfusion seizures: a manifestation of cerebral reperfusion injury after administration of recombinant tissue plasminogen activator for acute ischemic stroke. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20070101
The role of annexin II in angiogenesis and tumor progression: a potential therapeutic target. Current pharmaceutical design 20070101
Genistein and its analogue enhanced tissue plasminogen activator activity in HeLa S3. Pathophysiology of haemostasis and thrombosis 20070101
The stroke-thrombolytic predictive instrument: a predictive instrument for intravenous thrombolysis in acute ischemic stroke. Stroke 20061201
Evaluation of oxidative stress in the thrombolysis of pulmonary embolism. Journal of thrombosis and thrombolysis 20061201
Therapy for early reperfusion after stroke. Nature clinical practice. Cardiovascular medicine 20061201
Effects of atorvastatin on inflammatory and fibrinolytic parameters in patients with chronic kidney disease. Journal of the American Society of Nephrology : JASN 20061201
Synthesis of 1,4-diphenylbutadiene derivatives: novel inducer of tissue-type plasminogen activator (t-PA) in cultured bovine endothelial cells. Chemical & pharmaceutical bulletin 20061201
Nicotine treatment induces expression of matrix metalloproteinases in human osteoblastic Saos-2 cells. Acta biochimica et biophysica Sinica 20061201
[Effects of resolving phlegm method on fibrinolytic status in non-alcoholic steatohepatitis patients of phlegm and blood-stasis syndrome]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20061201
Adjunctive low-dose doxycycline therapy effect on clinical parameters and gingival crevicular fluid tissue plasminogen activator levels in chronic periodontitis. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061201
[Effect of electroacupuncture combined with medication on vascular endothelial cells in the compound hypertension and hyperlipemia rat]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20061201
The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1. The Journal of neuroscience : the official journal of the Society for Neuroscience 20061122
Evolving therapeutic approaches to treating acute ischemic stroke. Journal of the neurological sciences 20061115
Predicting abnormal coagulation in ischemic stroke: reducing delay in rt-PA use. Neurology 20061114
In-patient management and treatment satisfaction after intravitreous plasminogen activator injection. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20061101
Expression of the non-glycosylated kringle domain of tissue type plasminogen activator in Pichia and its anti-endothelial cell activity. Protein expression and purification 20061101
Involvement of tissue plasminogen activator-plasmin system in depolarization-evoked dopamine release in the nucleus accumbens of mice. Molecular pharmacology 20061101
Neuronal overexpression of tissue-type plasminogen activator does not enhance sensory axon regeneration or locomotor recovery following dorsal hemisection of adult mouse thoracic spinal cord. Journal of neuroscience research 20061101
The role of neutrophils and oxygen free radicals in post-operative adhesions. The Journal of surgical research 20061101
Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line. Metabolism: clinical and experimental 20061101
Inverse relation between diastolic blood pressure and long-term outcomes in patients undergoing pharmacoinvasive therapy for myocardial infarction: the J-shaped relation in the contemporary era of revascularisation. Journal of cardiovascular medicine (Hagerstown, Md.) 20061101
Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage. Nature medicine 20061101
Investigation of the safety of tenecteplase to the outer retina. Clinical & experimental ophthalmology 20061101
Plasminogen activator inhibitor-1 impairs plasminogen activation-mediated vascular smooth muscle cell apoptosis. Thrombosis and haemostasis 20061101
[Cerebral infarction]. Nihon rinsho. Japanese journal of clinical medicine 20061101
Transfer for urgent percutaneous coronary intervention early after thrombolysis for ST-elevation myocardial infarction: the TRANSFER-AMI pilot feasibility study. The Canadian journal of cardiology 20061101
Livedoid vasculopathy associated with plasminogen activator inhibitor-1 promoter homozygosity (4G/4G) treated successfully with tissue plasminogen activator. Archives of dermatology 20061101
Novel therapies for acute ischemic stroke. The Israel Medical Association journal : IMAJ 20061101
Glycosylation variant analysis of recombinant human tissue plasminogen activator produced in urea-cycle-enzyme-expressing Chinese hamster ovary (CHO) cell line. Journal of bioscience and bioengineering 20061101
Disruption of tissue plasminogen activator gene reduces macrophage migration. Biochemical and biophysical research communications 20061027
Short-term effects of low-dose atorvastatin on inflammatory status and lipid profiles in perimenopausal hypercholesterolemic, hypertriglyceridemic women. International journal of cardiology 20061026
Pro-urokinase-type plasminogen activator is a substrate for hepsin. The Journal of biological chemistry 20061013
Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans. Circulation 20061010
Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lipopolysaccharide and methylprednisolone. Bone 20061001
NXY-059 for acute ischemic stroke: the promise of neuroprotection is finally realized? Stroke 20061001
NXY-059: a hopeful sign in the treatment of stroke. Stroke 20061001
Signal transduction pathways involved in the stimulation of tissue type plasminogen activator by interleukin-1alpha and Porphyromonas gingivalis in human osteosarcoma cells. Journal of periodontal research 20061001
Fibrinolytic response to exercise in women using third-generation oral contraceptives. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20061001
Prosthetic valve thrombosis presenting as an acute embolic myocardial infarction in a pregnant patient: issues on anticoagulation regimens and thrombolytic therapy. Echocardiography (Mount Kisco, N.Y.) 20061001
Gene polymorphisms implicated in influencing susceptibility to venous and arterial thromboembolism: frequency distribution in a healthy German population. Thrombosis and haemostasis 20061001
Post-translational modifications in the context of therapeutic proteins. Nature biotechnology 20061001
Effect of combined therapy with thrombolysis and citicoline in a rat model of embolic stroke. Journal of the neurological sciences 20060925
A novel fibrinogen variant (fibrinogen Seoul II; AalphaGln328Pro) characterized by impaired fibrin alpha-chain cross-linking. Blood 20060915
LRP and alphavbeta3 mediate tPA activation of smooth muscle cells. American journal of physiology. Heart and circulatory physiology 20060901
Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity. Journal of neurochemistry 20060901
Evaluation of t-PA, PAI-2, IL-1beta and PGE(2) in gingival crevicular fluid of rheumatoid arthritis patients with periodontal disease. Journal of clinical periodontology 20060901
Role of abciximab in the treatment of coronary artery disease. Expert opinion on biological therapy 20060901
Time to reconsider saline as the ideal rinsing solution during abdominal surgery. American journal of surgery 20060901
Impact of extracellular matrix remodeling on ovulation and the folliculo-luteal transition. Seminars in reproductive medicine 20060901
Use of heparin versus lepirudin flushes to prevent withdrawal occlusion of central venous access devices. Pharmacotherapy 20060901
Taming the clot-buster tPA. Nature medicine 20060901
Suppression of tumor growth and invasion in 9,10 dimethyl benz(a) anthracene induced mammary carcinoma by the plant bioflavonoid quercetin. Chemico-biological interactions 20060825
Ethanol modifies the effect of handling stress on gene expression: problems in the analysis of two-way gene expression studies in mouse brain. Brain research 20060802
Multicenter study of the European Assessment Group for Lysis in the Eye (EAGLE) for the treatment of central retinal artery occlusion: design issues and implications. EAGLE Study report no. 1 : EAGLE Study report no. 1. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060801
Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060801
Catheter lock solutions influence staphylococcal biofilm formation on abiotic surfaces. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801
Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic stroke. Stroke 20060801
Neuroprotection and thrombolysis: combination therapy in acute ischaemic stroke. Expert opinion on pharmacotherapy 20060801
Intravitreal tissue plasminogen activator to treat macular edema associated with branch retinal vein occlusion. American journal of ophthalmology 20060801
TNF-alpha mediated suppression of tissue type plasminogen activator expression in vascular endothelial cells is NF-kappaB- and p38 MAPK-dependent. Journal of thrombosis and haemostasis : JTH 20060801
Arteriographic demonstration of slow antegrade opacification distal to a cerebrovascular thromboembolic occlusion site as a favorable indicator for intra-arterial thrombolysis. AJNR. American journal of neuroradiology 20060801
Argatroban tPA stroke study: study design and results in the first treated cohort. Archives of neurology 20060801
Relationship of glucose concentrations with PAI-1 and t-PA in subjects with normal glucose tolerance. Diabetic medicine : a journal of the British Diabetic Association 20060801
Activity of Ginkgo biloba extract and quercetin on thrombomodulin expression and tissue-type plasminogen activator secretion by human umbilical vein endothelial cells. Biomedical and environmental sciences : BES 20060801
Thrombolysis in patients older than 80 years with acute ischaemic stroke: Canadian Alteplase for Stroke Effectiveness Study. Journal of neurology, neurosurgery, and psychiatry 20060701
Recombinant tissue plasminogen activator injected into the vitreous cavity may penetrate the retinal veins of a porcine model of vascular occlusion. The British journal of ophthalmology 20060701
Purification and characterization of a staphylokinase variant, K35R. Biotechnology and applied biochemistry 20060701
A comparison of pharmacologic therapy with/without timely coronary intervention vs. primary percutaneous intervention early after ST-elevation myocardial infarction: the WEST (Which Early ST-elevation myocardial infarction Therapy) study. European heart journal 20060701
Pentoxifylline, a methyl xanthine derivative, reduces peritoneal adhesions and increases peritoneal fibrinolysis in rats. The Tohoku journal of experimental medicine 20060701
Recombinant P-selectin glycoprotein ligand-immunoglobulin, a P-selectin antagonist, as an adjunct to thrombolysis in acute myocardial infarction. The P-Selectin Antagonist Limiting Myonecrosis (PSALM) trial. American heart journal 20060701
Pregnancy and prosthetic atrioventricular valve thrombosis. Clinical cardiology 20060701
[Surgical treatment of submacular hemorrhage combined with tissue plasminogen activator (a case report)]. Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 20060701
Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice. The EMBO journal 20060621
In vitro effect of the potent poly(ADP-ribose) polymerase (PARP) inhibitor INO-1001 alone and in combination with aspirin, eptifibatide, tirofiban, enoxaparin or alteplase on haemostatic parameters. Life sciences 20060620
[Acute ischemia of the hand after intra-arterial injection of flunitrazepam. Local combined fibrinolysis therapy in three cases]. Deutsche medizinische Wochenschrift (1946) 20060616
Atorvastatin downregulates tissue plasminogen activator-aggravated genes mediating coagulation and vascular permeability in single cerebral endothelial cells captured by laser microdissection. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060601
Fibroblast growth factor 2 and transforming growth factor beta1 synergism in human bronchial smooth muscle cell proliferation. American journal of respiratory cell and molecular biology 20060601
Iliofemoral deep vein thrombosis in childhood; developing a management protocol. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20060601
Changes in coagulation and fibrinolysis of post-SARS osteonecrosis in a Chinese population. International orthopaedics 20060601
Plasma homocysteine affects fibrin clot permeability and resistance to lysis in human subjects. Arteriosclerosis, thrombosis, and vascular biology 20060601
Folate deficiency induced hyperhomocysteinemia changes the expression of thrombosis-related genes. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20060601
Thrombolytic therapy in pregnancy. Journal of thrombosis and thrombolysis 20060601
Regulation of endogenous tissue-type plasminogen activator expression is modulated by the -7351C>T enhancer polymorphism. Journal of thrombosis and haemostasis : JTH 20060601
A study of retinal penetration of intravitreal tenecteplase in pigs. Investigative ophthalmology & visual science 20060601
Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity. Neuron 20060601
Hyperglycemia stimulates coagulation, whereas hyperinsulinemia impairs fibrinolysis in healthy humans. Diabetes 20060601
The effects of thiazide and thiazide-potassium sparing diuretics on fibrinolytic system parameters. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20060601
Expression and clinical signification of cytosolic hyaluronan levels in invasive breast cancer. Breast cancer research and treatment 20060601
[Advanced medical therapy in patients with acute ischemic stroke]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060601
Targeting hypertension with valsartan: Lessons learned from the Valsartan/HCTZ versus Amlodipine in stage II hypertensive patients (VASt) trial. Journal of the renin-angiotensin-aldosterone system : JRAAS 20060601
Efficacy and safety of unfractionated heparin versus enoxaparin: a pooled analysis of ASSENT-3 and -3 PLUS data. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060509
Low-molecular-weight heparins as adjunctive therapy to thrombolytics: extracting the best data. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060509
Activity-dependent release of tissue plasminogen activator from the dendritic spines of hippocampal neurons revealed by live-cell imaging. Journal of neurobiology 20060501
Impaired fibrinolytic activity in type II diabetes: correlation with urinary albumin excretion and progression of renal disease. Kidney international 20060501
The management of retinal vein occlusion: is interventional ophthalmology the way forward? The British journal of ophthalmology 20060501
Pharmacologic management of ischemic stroke: relevance to stem cell therapy. Experimental neurology 20060501
Fibrinolytic dysfunction in insulin-resistant women with previous gestational diabetes. European journal of clinical investigation 20060501
Relation of depressive mood to plasminogen activator inhibitor, tissue plasminogen activator, and fibrinogen levels in patients with versus without coronary heart disease. The American journal of cardiology 20060501
Is IV tissue plasminogen activator beneficial in patients with hyperdense artery sign? Neurology 20060425
Insulin-like growth factor-binding protein-5 activates plasminogen by interaction with tissue plasminogen activator, independently of its ability to bind to plasminogen activator inhibitor-1, insulin-like growth factor-I, or heparin. The Journal of biological chemistry 20060421
DBC1 re-expression alters the expression of multiple components of the plasminogen pathway. Oncogene 20060413
Researchers focus on improving treatments for acute ischemic stroke. JAMA 20060412
Sildenafil improves coronary artery patency in a canine model of platelet-mediated cyclic coronary occlusion after thrombolysis. Journal of the American College of Cardiology 20060404
Memantine reduces hematoma expansion in experimental intracerebral hemorrhage, resulting in functional improvement. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060401
Pretreatment hemostatic markers of symptomatic intracerebral hemorrhage in patients treated with tissue plasminogen activator. Stroke 20060401
Melatonin attenuates the postischemic increase in blood-brain barrier permeability and decreases hemorrhagic transformation of tissue-plasminogen activator therapy following ischemic stroke in mice. Journal of pineal research 20060401
Impaired capacity for stimulated fibrinolysis in primary hypertension is restored by antihypertensive therapy. Hypertension (Dallas, Tex. : 1979) 20060401
A proteomic approach to the identification of new tPA receptors in pancreatic cancer cells. Proteomics 20060401
Management of subretinal macular haemorrhage by direct administration of tissue plasminogen activator. The British journal of ophthalmology 20060401
Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes. Diabetes 20060401
Rofecoxib regulates the expression of genes related to the matrix metalloproteinase pathway in humans: implication for the adverse effects of cyclooxygenase-2 inhibitors. Clinical pharmacology and therapeutics 20060401
A comparative investigation on different refolding strategies of recombinant human tissue-type plasminogen activator derivative. Biotechnology letters 20060401
Is delayed facilitated percutaneous coronary intervention better than immediate in reperfused myocardial infarction? Six months follow up findings. Journal of thrombosis and thrombolysis 20060401
Massive pulmonary embolism in a Lebanese patient doubly heterozygous for MTHFR and Factor V Leiden presenting with syncope and treated with tenecteplase. Journal of thrombosis and thrombolysis 20060401
Monitoring of plasmin and plasminogen activator activity in blood of patients under fibrinolytic treatment by reteplase. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20060401
Melanotransferrin stimulates t-PA-dependent activation of plasminogen in endothelial cells leading to cell detachment. Biochimica et biophysica acta 20060401
Structural basis of the cofactor function of denatured albumin in plasminogen activation by tissue-type plasminogen activator. Biochemical and biophysical research communications 20060317
Interaction of a plasminogen activator proteinase, LV-PA with human alpha2-macroglobulin. Toxicon : official journal of the International Society on Toxinology 20060315
Vascular and fibrinolytic effects of intra-arterial tumour necrosis factor-alpha in patients with coronary heart disease. Clinical science (London, England : 1979) 20060301
Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation, in non-diabetic individuals. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301
Effects of lactate dehydrogenase suppression and glycerol-3-phosphate dehydrogenase overexpression on cellular metabolism. Molecular and cellular biochemistry 20060301
Successful intraoperative use of recombinant tissue plasminogen activator during liver transplantation complicated by massive intracardiac/pulmonary thrombosis. Anesthesia and analgesia 20060301
Effects of intravenous administration of tissue plasminogen activator before thrombectomy in patients with acute myocardial infarction. Circulation journal : official journal of the Japanese Circulation Society 20060301
Emerging drugs in peripheral arterial disease. Expert opinion on emerging drugs 20060301
Effect of intrafollicular indomethacin injection on gonadotropin surge-induced expression of select extracellular matrix degrading enzymes and their inhibitors in bovine preovulatory follicles. Reproduction (Cambridge, England) 20060301
Thrombolysis in fulminant purpura: observations on changes in microcirculatory perfusion during successful treatment. Thrombosis and haemostasis 20060301
[Waran following thrombolysis with Actilyse]. Lakartidningen 20060301
Acute embolic stroke after electroconvulsive therapy. The journal of ECT 20060301
[Tissue plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) in children with ulcerative colitis]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060301
Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia. Biochemistry 20060227
Effects of four different regimens of hormone replacement therapy on hemostatic parameters: a prospective randomized study. Maturitas 20060220
Primary versus tenecteplase-facilitated percutaneous coronary intervention in patients with ST-segment elevation acute myocardial infarction (ASSENT-4 PCI): randomised trial. Lancet (London, England) 20060218
NXY-059 for acute ischemic stroke. The New England journal of medicine 20060209
Phosphodiesterase type 5 inhibition does not reverse endothelial dysfunction in patients with coronary heart disease. Heart (British Cardiac Society) 20060201
Urokinase (u-PA) is produced by collecting duct principal cells and is post-transcriptionally regulated by SV40 large-T, arginine vasopressin, and epidermal growth factor. Journal of cellular physiology 20060201
3alpha-OL-5-beta-pregnan-20-one hemisuccinate, a steroidal low-affinity NMDA receptor antagonist improves clinical rating scores in a rabbit multiple infarct ischemia model: synergism with tissue plasminogen activator. Experimental neurology 20060201
Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator. Stroke 20060201
Activation of the coagulation system during coronary artery bypass grafting: comparison between on-pump and off-pump techniques. The Journal of thoracic and cardiovascular surgery 20060201
What's new in stroke prevention and treatment. Expert review of neurotherapeutics 20060201
Subcutaneous enoxaparin following thrombolysis and intravenous unfractionated heparin in ST-elevation acute myocardial infarction: safety and efficacy of low vs full dose. Minerva cardioangiologica 20060201
[Role of tissue plasminogen activator in the rewarding effect of morphine]. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 20060201
Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression. The Journal of biological chemistry 20060127
Nitric oxide mediates neurodegeneration and breakdown of the blood-brain barrier in tPA-dependent excitotoxic injury in mice. Journal of cell science 20060115
Plasma TAFI and soluble CD40 ligand do not predict reperfusion following thrombolysis for acute myocardial infarction. Thrombosis research 20060101
Changes in fibrinolysis following exercise above and below lactate threshold. Thrombosis research 20060101
Alteplase treatment affects circulating matrix metalloproteinase concentrations in patients with ST segment elevation acute myocardial infarction. Thrombosis research 20060101
Effect of pulsed estrogen therapy on hemostatic markers in comparison with oral estrogen regimen in postmenopausal women. Gynecologic and obstetric investigation 20060101
The possible role of tissue-type plasminogen activator and the plasminogen system in the pathogenesis of major depression. Medical hypotheses 20060101
Late-onset donor-to-host transmission of Candida glabrata following corneal transplantation. Cornea 20060101
Treatment of catheter occlusion in pediatric patients. JPEN. Journal of parenteral and enteral nutrition 20060101
Expression of protease nexin-1 and plasminogen activators during follicular growth and the periovulatory period in cattle. Reproduction (Cambridge, England) 20060101
Review article: updates in the pathogenesis and therapy of hepatic sinusoidal obstruction syndrome. Alimentary pharmacology & therapeutics 20060101
Offshore innovation. JEMS : a journal of emergency medical services 20060101
The effect of vitamin E, L-arginine, N-nitro L-arginine methyl ester and forskolin on endocrine and metabolic changes of rats exposed to acute cold stress. Saudi medical journal 20060101
The effects of rosiglitazone treatment on the fibrinolytic system in patients with type 2 diabetes mellitus. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20060101
[Expression of epidermal growth factor receptor (EGFR) in hormone-independent breast cancers]. Revista espanola de medicina nuclear 20060101
Treatment of embolic stroke in rats with bortezomib and recombinant human tissue plasminogen activator. Thrombosis and haemostasis 20060101
Edaravone in acute ischemic stroke. Internal medicine (Tokyo, Japan) 20060101
Elastic modulus-based thrombelastographic quantification of plasma clot fibrinolysis with progressive plasminogen activation. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20060101
Prevention of catheter lumen occlusion with rT-PA versus heparin (Pre-CLOT): study protocol of a randomized trial [ISRCTN35253449]. BMC nephrology 20060101
A new technique for the subretinal injection of small volumes by using a modified viscous fluid injector system. Retina (Philadelphia, Pa.) 20060101
The ischemic penumbra: a new opportunity for neuroprotection. Cerebrovascular diseases (Basel, Switzerland) 20060101
Thrombolysis and neuroprotection in cerebral ischemia. Cerebrovascular diseases (Basel, Switzerland) 20060101
Other neuroprotective therapies on trial in acute stroke. Cerebrovascular diseases (Basel, Switzerland) 20060101
New modalities for the treatment of acute cardioembolic stroke. Internal medicine (Tokyo, Japan) 20060101
Effect of troglitazone on serum gamma-glutamyltransferase activity and plasma t-PA/PAI-1 complex in type 2 diabetic patients. Arzneimittel-Forschung 20060101
Monitoring of glycoprotein products in cell culture lysates using lectin affinity chromatography and capillary HPLC coupled to electrospray linear ion trap-Fourier transform mass spectrometry (LTQ/FTMS). Biotechnology progress 20060101
The influence of thrombolytic therapy on C-reactive protein in ST-segment elevation acute myocardial infarction. Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101
Reteplase: a review of its use in the management of thrombotic occlusive disorders. American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101
Effect of activase level and isoform on the thermotolerance of photosynthesis in Arabidopsis. Journal of experimental botany 20060101
[Regulation with alpha-2-antiplasmin of Glu-plasminogen activation by tissue activator on fibrin]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101
Stability of protein-encapsulating DRV liposomes after freeze-drying: A study with BSA and t-PA. Journal of liposome research 20060101
Pharmacological enhancement of the kallikrein-kinin system promotes anti-fibrotic responses in human mesangial cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101
Gene polymorphisms of fibrinolytic enzymes in coal workers' pneumoconiosis. Archives of environmental & occupational health 20060101
Orolingual angioedema associated with ACE inhibitor use after rtPA treatment of acute stroke. Neurology 20051227
Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis. Circulation 20051220
Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins. FEBS letters 20051219
Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis. Neurology 20051213
Construction and characterization of a t-PA mutant for use in ATTEMPTS: a drug delivery system for achieving targeted thrombolysis. Journal of controlled release : official journal of the Controlled Release Society 20051210
Results of intravitreal tissue plasminogen activator and expansile gas injection for submacular haemorrhage in Thais. Eye (London, England) 20051201
Examination of the signal transduction pathways leading to upregulation of tissue type plasminogen activator by Porphyromonas endodontalis in human pulp cells. International endodontic journal 20051201
Thrombolysis of venous and arterial thrombosis by catheter-directed low-dose infusion of tissue plasminogen activator in children. Journal of pediatric hematology/oncology 20051201
Superior vena cava thrombus treated with low-dose, peripherally administered recombinant tissue plasminogen activator in a child: case report and review of the literature. Journal of pediatric hematology/oncology 20051201
[Effects of chronic mercury poisoning on blood coagulation and fibrinolysis systems]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20051201
Influence of stearic acid on hemostatic risk factors in humans. Lipids 20051201
Pneumatic displacement of a dense submacular hemorrhage with or without tissue plasminogen activator. Chang Gung medical journal 20051201
[A randomized clinical trial on comparison of weight-adjusted dose with low dose recombinant tissue-type plasminogen activator on Chinese patients with acute myocardial infarction]. Zhonghua xin xue guan bing za zhi 20051201
Vitrectomy for the treatment of submacular hemorrhages from macular degeneration: a comparison of submacular hemorrhage/membrane removal and submacular tissue plasminogen activator-assisted pneumatic displacement. Transactions of the American Ophthalmological Society 20051201
Multitargeted effects of statin-enhanced thrombolytic therapy for stroke with recombinant human tissue-type plasminogen activator in the rat. Circulation 20051129
Reducing the burden of stroke. Lancet (London, England) 20051119
Time to treatment and the impact of a physician on prehospital management of acute ST elevation myocardial infarction: insights from the ASSENT-3 PLUS trial. Heart (British Cardiac Society) 20051101
Tissue plasminogen activator in brain tissues infected with transmissible spongiform encephalopathies. Neurobiology of disease 20051101
Endothelial t-PA release is impaired in overweight and obese adults but can be improved with regular aerobic exercise. American journal of physiology. Endocrinology and metabolism 20051101
Hemostatic factors and estrogen during the menopausal transition. The Journal of clinical endocrinology and metabolism 20051101
Human gender differences in fibrinolytic responses to exercise training and their determinants. Experimental physiology 20051101
Angiotensin-converting enzyme inhibition increases basal vascular tissue plasminogen activator release in women but not in men. Arteriosclerosis, thrombosis, and vascular biology 20051101
Impact of simvastatin on hemostatic and fibrinolytic regulators in Type 2 diabetes mellitus. Diabetes research and clinical practice 20051101
Safety of adjunctive intracoronary thrombolytic therapy during complex percutaneous coronary intervention: initial experience with intracoronary tenecteplase. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051101
Endothelial function and its assessment. Expert opinion on investigational drugs 20051101
Arterial thrombosis associated with heterozygous factor V Leiden disorder, hyperhomocysteinemia, and peripheral arterial disease: importance of synergistic factors. Journal of vascular surgery 20051101
Prohemorrhagic and bleeding time activities of recombinant tissue plasminogen activator, heparin, aspirin, and a glycoprotein IIb/IIIa antagonist. Journal of neurotrauma 20051101
The pursuit of excellence in acute stroke care. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20051101
TPA use for stroke in the Registry of the Canadian Stroke Network. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20051101
Intra-arterial thrombolysis for retinal artery occlusion: the Calgary experience. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20051101
Levels of t-PA and PAI-2 in gingival crevicular fluid during orthodontic tooth movement in adults. Australian orthodontic journal 20051101
Predictors of major neurologic improvement after thrombolysis in acute stroke. Neurology 20051025
Matrix-degrading enzymes tissue plasminogen activator and matrix metalloprotease-3 in the hypothalamo-neurohypophysial system. Brain research 20051005
A new recombinant thrombolytic and antithrombotic agent with higher fibrin affinity--a staphylokinase variant. I. In vitro study. Journal of thrombosis and haemostasis : JTH 20051001
Markers of endothelial dysfunction and severity of hypoxaemia in the Eisenmenger syndrome. Cardiology in the young 20051001
The effects of short-term raloxifene therapy on fibrinolysis markers: TAFI, tPA, and PAI-1. Acta obstetricia et gynecologica Scandinavica 20051001
Lipid, lipoproteins, C-reactive protein, and hemostatic factors at baseline in the diabetes prevention program. Diabetes care 20051001
[Changes of blood coagulative and fibrinolytic systems and functions of pulmonary vascular endothelium in patients with pulmonary thromboembolism]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20051001
[The influence of tissue and plasma angiotensin converting enzyme inhibitors on haemostasis with respect to experimental and clinical investigations]. Kardiologia polska 20051001
Plasminogen activator inhibitor-1 and tissue-plasminogen activator in minority adolescents with type 2 diabetes and obesity. Pediatric research 20050901
Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia. Stroke 20050901
Tissue-plasminogen activator-induced ischemic brain injury is reversed by melatonin: role of iNOS and Akt. Journal of pineal research 20050901
Functional recovery after embolic stroke in rodents by activated protein C. Annals of neurology 20050901
In vivo generation of angiostatin isoforms by administration of a plasminogen activator and a free sulfhydryl donor: a phase I study of an angiostatic cocktail of tissue plasminogen activator and mesna. Clinical cancer research : an official journal of the American Association for Cancer Research 20050901
IV tPA for acute ischemic stroke: results of the first 101 patients in a community practice. The neurologist 20050901
Facilitated percutaneous coronary intervention (PCI) in patients with acute ST-elevation myocardial infarction: comparison of prehospital tirofiban versus fibrinolysis before direct PCI. International journal of cardiology 20050818
Hemostatic markers of recanalization in patients with ischemic stroke treated with rt-PA. Neurology 20050809
Combined angioplasty and pharmacological intervention versus thrombolysis alone in acute myocardial infarction (CAPITAL AMI study). Journal of the American College of Cardiology 20050802
Blood acylpeptide hydrolase activity is a sensitive marker for exposure to some organophosphate toxicants. Toxicological sciences : an official journal of the Society of Toxicology 20050801
Acute hyperglycemia state is associated with lower tPA-induced recanalization rates in stroke patients. Stroke 20050801
Endothelial dysfunction occurs in peripheral circulation patients with acute and stable coronary artery disease. American journal of physiology. Heart and circulatory physiology 20050801
Partial rescue of the perfusion deficit area by thrombolysis. Journal of magnetic resonance imaging : JMRI 20050801
Plasminogen activators promote excitotoxicity-induced retinal damage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801
Widening the window. Strategies to buy time in treating ischemic stroke. Scientific American 20050801
Hypoattenuation on CT angiographic source images predicts risk of intracerebral hemorrhage and outcome after intra-arterial reperfusion therapy. AJNR. American journal of neuroradiology 20050801
Estrogen receptor-alpha thymidine and adenine repeat polymorphism and endothelial fibrinolytic regulation in postmenopausal women. American journal of obstetrics and gynecology 20050801
Proinflammatory cytokines, transforming growth factor-beta1, and fibrinolytic enzymes in loculated and free-flowing pleural exudates. Chest 20050801
Ischaemic stroke: acute-phase drug therapy. Mostly aspirin and heparin. Prescrire international 20050801
[Testosterone's effect on tPA and PAI-1 mRNA levels of HUVEC]. Zhonghua nan ke xue = National journal of andrology 20050801
[Role of endogenous tPA in stroke]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20050801
[Effects of co-expression plasmid of human tPA and VEGF165 on the proliferation of vascular cells and fibrinolysis activity]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050801
Structural requirements for activation of latent platelet-derived growth factor CC by tissue plasminogen activator. The Journal of biological chemistry 20050722
The metabolic syndrome and insulin resistance: relationship to haemostatic and inflammatory markers in older non-diabetic men. Atherosclerosis 20050701
Measurement of plasminogen activator system components in plasma and tumor tissue extracts obtained from patients with breast cancer: an EORTC Receptor and Biomarker Group collaboration. Oncology reports 20050701
Low level of tissue plasminogen activator activity in non-diabetic patients with a first myocardial infarction. Journal of internal medicine 20050701
Instructive ECG series in massive bilateral pulmonary embolism. Heart (British Cardiac Society) 20050701
Attenuation of extravasation of tissue plasminogen activator by the free radical scavenger, edaravone: evaluation in a rat thromboembolic stroke model. Neurological research 20050701
Expression of tissue plasminogen activator during eye development. Experimental eye research 20050701
Impaired bradykinin response to ischaemia and exercise in patients with mild congestive heart failure during angiotensin-converting enzyme treatment. Relationships with endothelial function, coagulation and inflammation. British journal of haematology 20050701
Thromboembolic cerebral ischaemic attack complicating cardiac catheterization. Successful local thrombolytic therapy with reduced dose rt-PA. Zeitschrift fur Kardiologie 20050701
Tenecteplase and tirofiban in ST-segment elevation acute myocardial infarction: results of a randomized trial. American heart journal 20050701
Facilitated percutaneous coronary intervention for acute ST-segment elevation myocardial infarction: results from the prematurely terminated ADdressing the Value of facilitated ANgioplasty after Combination therapy or Eptifibatide monotherapy in acute Myocardial Infarction (ADVANCE MI) trial. American heart journal 20050701
Role of MC-1 alone and in combination with tissue plasminogen activator in focal ischemic brain injury in rats. Journal of neurosurgery 20050701
[Pro- and anti-addictive factors related to drug addiction]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20050701
Effects of cilazapril on endothelial cell function and fibrinolysis system in atrial fibrillation. Chinese medical journal 20050620
Popliteal vascular entrapment syndrome caused by a rare anomalous slip of the lateral head of the gastrocnemius muscle. Skeletal radiology 20050601
Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050601
Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury. Stroke 20050601
Role of tissue plasminogen activator/plasmin cascade in delayed neuronal death after transient forebrain ischemia. Neuroscience letters 20050601
The effects of platelet count on clot retraction and tissue plasminogen activator-induced fibrinolysis on thrombelastography. Anesthesia and analgesia 20050601
Modification by the tissue plasminogen activator-plasmin system of morphine-induced dopamine release and hyperlocomotion, but not anti-nociceptive effect in mice. Journal of neurochemistry 20050601
Angiotensin II enhances thrombosis development in renovascular hypertensive rats. Thrombosis and haemostasis 20050601
Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational Study. Thrombosis and haemostasis 20050601
Global fibrinolytic capacity in patients with subclinical hypothyroidism. Endocrine journal 20050601
Stimulated release of tissue plasminogen activator from artery wall sympathetic nerves: implications for stress-associated wall damage. Stress (Amsterdam, Netherlands) 20050601
Metastasis-associated protein S100A4 induces angiogenesis through interaction with Annexin II and accelerated plasmin formation. The Journal of biological chemistry 20050527
Effects of amino acid additions on ammonium stressed CHO cells. Journal of biotechnology 20050525
Chinese medicine compound Changtong oral liquid on postoperative intestinal adhesions. World journal of gastroenterology 20050521
Anuria due to acute bilateral renal vein occlusion after thrombolysis for pulmonary embolism. International journal of cardiology 20050511
Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation. The EMBO journal 20050504
Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis. Circulation 20050503
Oxygen glucose deprivation switches the transport of tPA across the blood-brain barrier from an LRP-dependent to an increased LRP-independent process. Stroke 20050501
Antithrombotic effects of rosiglitazone-metformin versus glimepiride-metformin combination therapy in patients with type 2 diabetes mellitus and metabolic syndrome. Pharmacotherapy 20050501
[Effect of Cilazapril on endothelial cell function and fibrinolysis system in the canine atrial fibrillation models]. Zhonghua xin xue guan bing za zhi 20050501
[Paroxysmal nocturnal hemoglobinuria]. Nihon rinsho. Japanese journal of clinical medicine 20050501
Levels of t-PA and PAI-2 in gingival crevicular fluid during orthodontic tooth movement in adults. Australian orthodontic journal 20050501
Uridine triphosphate (UTP) is released during cardiac ischemia. International journal of cardiology 20050428
3D-QSAR CoMFA studies on trypsin-like serine protease inhibitors: a comparative selectivity analysis. Bioorganic & medicinal chemistry 20050415
B1 kinin receptor does not contribute to vascular tone or tissue plasminogen activator release in the peripheral circulation of patients with heart failure. Arteriosclerosis, thrombosis, and vascular biology 20050401
Antiangiogenic activity of a domain deletion mutant of tissue plasminogen activator containing kringle 2. Arteriosclerosis, thrombosis, and vascular biology 20050401
Is heparin treatment the optimal management for cerebral venous thrombosis? Effect of abciximab, recombinant tissue plasminogen activator, and enoxaparin in experimentally induced superior sagittal sinus thrombosis. Stroke 20050401
Urokinase plasminogen activator, uPa receptor, and its inhibitor in vernal keratoconjunctivitis. Investigative ophthalmology & visual science 20050401
Tissue type plasminogen activator facilitates NMDA-receptor-mediated retinal apoptosis through an independent fibrinolytic cascade. Investigative ophthalmology & visual science 20050401
[Surgical approach to retinal vein occlusion]. Klinische Monatsblatter fur Augenheilkunde 20050401
Economic analysis of the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT-3) study: costs of reperfusion strategies in acute myocardial infarction. American heart journal 20050401
Retinal toxicity of commercial tissue plasminogen activator is mediated by the induction of nitric oxide in the mouse retinal primary cells. Current eye research 20050401
ACE inhibition reduces activity of the plasminogen/plasmin and MMP systems in the brain of spontaneous hypertensive stroke-prone rats. Neuroscience letters 20050316
Distribution of sympathetic tissue plasminogen activator (tPA) to a distant microvasculature. Journal of neuroscience research 20050315
Comparison of ST-segment resolution with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy versus fibrinolytic alone (data from four clinical trials). The American journal of cardiology 20050301
Prevention of intraperitoneal adhesions and abscesses by polysaccharides isolated from Phellinus spp in a rat peritonitis model. Annals of surgery 20050301
Uncovering the molecular side of alcohol addiction. The Lancet. Neurology 20050301
Alteplase as a catheter locking solution: in vitro evaluation of biochemical stability and antimicrobial properties. Journal of vascular and interventional radiology : JVIR 20050301
Tissue-type plasminogen activator (tPA) in breast cancer: relationship with clinicopathological parameters and prognostic significance. Breast cancer research and treatment 20050301
Acute administration of angiotensin converting enzyme inhibitors in thrombolysed myocardial infarction patients is associated with a decreased incidence of heart failure, but an increased re-infarction risk. Cardiovascular drugs and therapy 20050301
In vitro endothelial cell susceptibility to xenobiotics: comparison of three cell types. Cell biology and toxicology 20050301
Influence of withdrawal of statin treatment on proinflammatory response and fibrinolytic activity in humans: an effect independent on cholesterol elevation. International journal of cardiology 20050227
Phospholipase D1-promoted release of tissue plasminogen activator facilitates neurite outgrowth. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050216
Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. The Journal of biological chemistry 20050211
The t-PA -7351C>T enhancer polymorphism decreases Sp1 and Sp3 protein binding affinity and transcriptional responsiveness to retinoic acid. Blood 20050201
Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase. Stroke 20050201
Minocycline has no effect on the fibrinolytic activity of alteplase. The Annals of pharmacotherapy 20050201
The role of tissue plasminogen activator in methamphetamine-related reward and sensitization. Journal of neurochemistry 20050201
Predictive value of plasma plasminogen activator inhibitor-1 for coronary restenosis: dependence on stent implantation and antithrombotic medication. Journal of thrombosis and haemostasis : JTH 20050201
Prehospital thrombolysis perfomed by a ship's nurse with on-line physician consultation. Resuscitation 20050201
Catheter-directed thrombolysis for the management of postpartum deep venous thrombosis. Acta obstetricia et gynecologica Scandinavica 20050201
Drug dependence, synaptic plasticity, and tissue plasminogen activator. Journal of pharmacological sciences 20050201
Diet and aging: bearing on thrombosis and hemostasis. Seminars in thrombosis and hemostasis 20050201
Intravitreal tissue plasminogen activator and pneumatic displacement of submacular hemorrhage secondary to retinal artery macroaneurysm. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050201
Testosterone does not adversely affect fibrinogen or tissue plasminogen activator (tPA) and plasminogen activator inhibitor-1 (PAI-1) levels in 46 men with chronic stable angina. European journal of endocrinology 20050201
Tissue plasminogen activator and glial function. Glia 20050115
Activation of the {beta}-catenin/T-cell-specific transcription factor/lymphoid enhancer factor-1 pathway by plasminogen activators in ECV304 carcinoma cells. Cancer research 20050115
Domain V of beta2-glycoprotein I binds factor XI/XIa and is cleaved at Lys317-Thr318. The Journal of biological chemistry 20050114
Ontogenic study of the influence of tissue plasminogen activator (t-PA) in neonatal excitotoxic brain insult and the subsequent microglia/macrophage activation. Neuroscience 20050101
Effects of short-term treatment with metformin on markers of endothelial function and inflammatory activity in type 2 diabetes mellitus: a randomized, placebo-controlled trial. Journal of internal medicine 20050101
Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator. Journal of neurology, neurosurgery, and psychiatry 20050101
Sesamol regulates plasminogen activator gene expression in cultured endothelial cells: a potential effect on the fibrinolytic system. The Journal of nutritional biochemistry 20050101
Intra-arterial thrombolysis in patients treated with warfarin. Cerebrovascular diseases (Basel, Switzerland) 20050101
Intraocular haemorrhage after thrombolysis. Lancet (London, England) 20050101
Characterization of a small molecule PAI-1 inhibitor, ZK4044. Thrombosis research 20050101
Analysis of combined treatment of embolic stroke in rat with r-tPA and a GPIIb/IIIa inhibitor. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050101
FK419, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, ameliorates brain infarction associated with thrombotic focal cerebral ischemia in monkeys: comparison with tissue plasminogen activator. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050101
Evaluation of fibronectin, vitronectin, and leptin levels in coronary artery disease: impacts on thrombosis and thrombolysis. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20050101
Expression of plasminogen activators in preimplantation rat embryos developed in vivo and in vitro. Reproductive biology and endocrinology : RB&E 20050101
Dipyridamole enhances tissue plasminogen activator release by brain capillary endothelial cells. Thrombosis research 20050101
[Cytosolic pS2 levels and cellular proliferation in ER-positive and PgR-positive infiltrating ductal carcinomas of the breast]. Revista espanola de medicina nuclear 20050101
Left ventricular apical thrombus after systemic thrombolysis with recombinant tissue plasminogen activator in a patient with acute ischemic stroke. Cardiovascular ultrasound 20050101
Comparison of soluble thrombomodulin, von Willebrand factor, tPA/PAI-1 complex, and high-sensitivity CRP concentrations in serum, EDTA plasma, citrated plasma, and acidified citrated plasma (Stabilyte) stored at -70 degrees C for 8-11 years. Thrombosis research 20050101
Retinal endovascular surgery for central retinal vein occlusion: initial experience of four surgeons. Retina (Philadelphia, Pa.) 20050101
Decreased production of collagen Type III in cultured smooth muscle cells from varicose vein patients is due to a degradation by MMPs: possible implication of MMP-3. Journal of vascular research 20050101
Stroke units, tissue plasminogen activator, aspirin and neuroprotection: which stroke intervention could provide the greatest community benefit? Cerebrovascular diseases (Basel, Switzerland) 20050101
Tissue plasminogen activator in the bed nucleus of stria terminalis regulates acoustic startle. Neuroscience 20050101
The fibrinolytic system components are increased in systemic sclerosis and modulated by Alprostadil (alpha1 ciclodestryn). Clinical and experimental rheumatology 20050101
Inhibition of carboxypeptidase U (TAFIa) activity improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis. Thrombosis research 20050101
[Haemostatic and fibrinolytic variables in women with anorexia nervosa]. Psychiatria polska 20050101
Endovascular recanalization of internal carotid artery occlusion in acute ischemic stroke. AJNR. American journal of neuroradiology 20050101
Palm oil versus hydrogenated soybean oil: effects on serum lipids and plasma haemostatic variables. Asia Pacific journal of clinical nutrition 20050101
[Associations of hemostasis factors genes with early development of ischemic heart disease and manifestation of myocardial infarction in young age]. Kardiologiia 20050101
Systemic hemostasis with recombinant-activated factor VII followed by local thrombolysis with recombinant tissue plasminogen activator in intraventricular hemorrhage. Neurocritical care 20050101
Revisiting quality standards in hemodialysis vascular access: where is the bar? CANNT journal = Journal ACITN 20050101
[The influence of nitric oxide on the regulation of plasminogen activator inhibitor type 1 and tissue-type plasminogen activator expression]. Postepy biochemii 20050101
Tissue plasminogen activator-induced ischemic injury is reversed by NMDA antagonist MK-801 in vivo. Neuro-degenerative diseases 20050101
Experience-dependent pruning of dendritic spines in visual cortex by tissue plasminogen activator. Neuron 20041216
Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling. The Journal of biological chemistry 20041203
Neutral endopeptidase inhibition augments vascular actions of bradykinin in patients treated with angiotensin-converting enzyme inhibition. Hypertension (Dallas, Tex. : 1979) 20041201
Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C. Nature medicine 20041201
New functions for an old enzyme: nonhemostatic roles for tissue-type plasminogen activator in the central nervous system. Experimental biology and medicine (Maywood, N.J.) 20041201
Solid phase peptide synthesis on epoxy-bearing methacrylate monoliths. Journal of peptide science : an official publication of the European Peptide Society 20041201
Induction of uPA release in human peripheral blood lymphocytes by [deamino-Cysl,D-Arg8]-vasopressin (dDAVP). American journal of physiology. Endocrinology and metabolism 20041101
Impact of admission hyperglycemia on stroke outcome after thrombolysis: risk stratification in relation to time to reperfusion. Stroke 20041101
Editorial comment--Prime time for proactive blood glucose control? Stroke 20041101
Retinal vein cannulation with prolonged infusion of tissue plasminogen activator (t-PA) for the treatment of experimental retinal vein occlusion in dogs. American journal of ophthalmology 20041101
Elevation of plasminogen activators in cerebrospinal fluid of mice with eosinophilic meningitis caused by Angiostrongylus cantonensis. International journal for parasitology 20041101
The effect of homocysteine reduction by B-vitamin supplementation on markers of endothelial dysfunction. Thrombosis and haemostasis 20041101
The early history and development of thrombolysis in acute myocardial infarction. Journal of thrombosis and haemostasis : JTH 20041101
Regulation of local availability of active tissue-type plasminogen activator in vivo in man. Journal of thrombosis and haemostasis : JTH 20041101
A case of life-saving pharmacologic and mechanical coronary dethrombosis. Italian heart journal : official journal of the Italian Federation of Cardiology 20041101
The effects of atorvastatin treatment on the fibrinolytic system in dyslipidemic patients. Japanese heart journal 20041101
[Testosterone has beneficial effects on human umbilical vein endothelial cells]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20041101
[Homocysteine' s effect on tPA and PAI-1 gene expression in HUVEC]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20041101
Lack of improvement in patients with acute stroke after treatment with thrombolytic therapy: predictors and association with outcome. JAMA 20041020
Rapid, activity-induced increase in tissue plasminogen activator is mediated by metabotropic glutamate receptor-dependent mRNA translation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041020
Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science (New York, N.Y.) 20041015
Effect of delapril-manidipine combination vs irbesartan-hydrochlorothiazide combination on fibrinolytic function in hypertensive patients with type II diabetes mellitus. Journal of human hypertension 20041001
Polyploidisation of metastatic colon carcinoma cells by microtubule and tubulin interacting drugs: effect on proteolytic activity and invasiveness. International journal of oncology 20041001
Infarct reduction in rats following intraventricular administration of either tissue plasminogen activator (tPA) or its non-protease mutant S478A-tPA. Experimental neurology 20041001
Development of transplant renal artery thrombosis and signs of haemolytic-uraemic syndrome following the change from cyclosporin to tacrolimus in a renal transplant patient. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001
Outcome of ST-elevation myocardial infarction treated with thrombolysis in the unselected population is vastly different from samples of eligible patients in a large-scale clinical trial. American heart journal 20041001
Endophthalmitis after intravitreal injection of frozen preprepared tissue plasminogen activator (tPA) for pneumatic displacement of submacular hemorrhage. Retina (Philadelphia, Pa.) 20041001
Acute myocardial infarction following the use of antimigraine therapy. The Journal of invasive cardiology 20041001
2,7-Bis-(4-amidinobenzylidene)-cycloheptan-1-one dihydrochloride, tPA stop, prevents tPA-enhanced excitotoxicity both in vitro and in vivo. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20041001
[Treatment of venous thromboembolism in cancer patients]. Nihon rinsho. Japanese journal of clinical medicine 20041001
No association is found between the candidate genes of t-PA/plasminogen system and Japanese methamphetamine-related disorder: a collaborative study by the Japanese Genetics Initiative for Drug Abuse. Annals of the New York Academy of Sciences 20041001
Effects of histidine-proline-rich glycoprotein on plasminogen activation in solution and on surfaces. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20041001
Tissue plasminogen activator is a potent activator of PDGF-CC. The EMBO journal 20040929
Plasminogen activator and serine protease inhibitor-E2 (protease nexin-1) expression by bovine granulosa cells in vitro. Biology of reproduction 20040901
The sphingomyelin/ceramide pathway is involved in ERK1/2 phosphorylation, cell proliferation, and uPAR overexpression induced by tissue-type plasminogen activator. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040901
Targeting neuroprotection clinical trials to ischemic stroke patients with potential to benefit from therapy. Stroke 20040901
Admission fibrinolytic profile is associated with symptomatic hemorrhagic transformation in stroke patients treated with tissue plasminogen activator. Stroke 20040901
Impaired endothelial release of tissue-type plasminogen activator in patients with chronic kidney disease and hypertension. Hypertension (Dallas, Tex. : 1979) 20040901
The role of endogenous versus exogenous tPA on edema formation in murine ICH. Experimental neurology 20040901
Investigation of residues in the fibrin(ogen) gamma chain involved in tissue plasminogen activator binding and plasminogen activation. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20040901
Tissue plasminogen activator (t-PA) and placental plasminogen activator inhibitor (PAI-2) in gingival crevicular fluid from patients with Papillon-Lefèvre syndrome. Journal of clinical periodontology 20040901
Dose-finding based on efficacy-toxicity trade-offs. Biometrics 20040901
[Changes in tissue plasminogen activator and plasminogen activator inhibitor during administration of nitroglycerine into internal thoracic artery in dogs with acute myocardial ischemia]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20040901
The neurotoxicity of tissue plasminogen activator? Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040901
Effect of amlodipine-atorvastatin combination on fibrinolysis in hypertensive hypercholesterolemic patients with insulin resistance. American journal of hypertension 20040901
Antithrombotic and thrombolytic therapy for ischemic stroke: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 20040901
Altered NO function contributes to impairment of uPA and tPA cerebrovasodilation after brain injury. Journal of neurotrauma 20040901
Comparative analysis of the proteinase specificity in wild-type and stabilized plasminogen activator inhibitor-1: evidence for contribution of intramolecular flexibility. Biochemical and biophysical research communications 20040827
Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells. The EMBO journal 20040804
Extending the window for acute stroke treatment: thrombolytics plus CNS protective therapies. Experimental neurology 20040801
Lost in translation: taking neuroprotection from animal models to clinical trials. Experimental neurology 20040801
Coadministration of NXY-059 and tenecteplase six hours following embolic strokes in rabbits improves clinical rating scores. Experimental neurology 20040801
Pharmacology of caffeinol in embolized rabbits: clinical rating scores and intracerebral hemorrhage incidence. Experimental neurology 20040801
Update on stroke. Current opinion in neurology 20040801
Sequential treatment of central retinal vein occlusion with intravitreal tissue plasminogen activator and intravitreal triamcinolone. The British journal of ophthalmology 20040801
The complexity of tissue-type plasminogen activator: can serine protease inhibitors help in stroke management? Expert opinion on therapeutic targets 20040801
Thrombolytic therapy: no room for error. Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20040801
Effect of four oral contraceptives on hemostatic parameters. Contraception 20040801
Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB. European journal of biochemistry 20040801
Continuous tenecteplase infusion combined with peri/postprocedural platelet glycoprotein IIb/IIIa inhibition in peripheral arterial thrombolysis: initial safety and feasibility experience. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20040801
Management of macular edema in branch retinal vein occlusion with sheathotomy and recombinant tissue plasminogen activator. Retina (Philadelphia, Pa.) 20040801
Effects of all-trans retinoic acid or chemotherapy on the molecular regulation of systemic blood coagulation and fibrinolysis in patients with acute promyelocytic leukemia. Journal of thrombosis and haemostasis : JTH 20040801
Reductions in mRNA of the neuroprotective agent, neuroserpin, after cerebral ischemia/reperfusion in diabetic rats. Brain research 20040723
Effects of atorvastatin (10 mg) on hemostatic and inflammatory parameters in hyperlipidemic patients with angiographically proven coronary artery disease. The American journal of cardiology 20040715
Aborted myocardial infarction in patients with ST-segment elevation: insights from the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen-3 Trial Electrocardiographic Substudy. Journal of the American College of Cardiology 20040707
Changes in von Willebrand factor and fibrinolysis following a post-exercise cool-down. European journal of applied physiology 20040701
Vitamin C has no effect on endothelium-dependent vasomotion and acute endogenous fibrinolysis in healthy smokers. Journal of cardiovascular pharmacology 20040701
Plasminogen activators and plasminogen activator inhibitors in gingival crevicular fluid of cyclosporin A-treated patients. Journal of clinical periodontology 20040701
Comparison of t-PA and u-PA levels in maximal treadmill and deep-water running. Preventive medicine 20040701
Predictors of intracranial hemorrhage with fibrinolytic therapy in unselected community patients: a report from the FASTRAK II project. American heart journal 20040701
Enhancement of enzymatic fibrinolysis with 2-MHz ultrasound and microbubbles. Journal of thrombosis and haemostasis : JTH 20040701
Tissue-type plasminogen activator and neuroserpin: a well-balanced act in the nervous system? Trends in cardiovascular medicine 20040701
[Effects of scorpion toxins on the cardiovascular system]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040701
Established and emerging plasma biomarkers in the prediction of first atherothrombotic events. Circulation 20040629
Comparison of rapidity of coronary recanalization in men with tenecteplase versus alteplase in acute myocardial infarction. The American journal of cardiology 20040615
The effect of combined thrombolysis with rtPA and tirofiban on ischemic brain lesions. Neurology 20040608
Interrelationships between the fibrinolytic system and lipoproteins in the pathogenesis of coronary atherosclerosis. Atherosclerosis 20040601
Prion protein stimulates tissue-type plasminogen activator-mediated plasmin generation via a lysine-binding site on kringle 2. Journal of thrombosis and haemostasis : JTH 20040601
Thrombotic microangiopathy (TMA) and stroke due to human herpesvirus-6 (HHV-6) reactivation in an adult receiving high-dose melphalan with autologous peripheral stem cell transplantation. American journal of hematology 20040601
Combined assessment of thrombolysis in myocardial infarction flow grade, myocardial perfusion grade, and ST-segment resolution to evaluate epicardial and myocardial reperfusion. The American journal of cardiology 20040601
Variations in pre-hospital fibrinolysis process of care: insights from the Assessment of the Safety and Efficacy of a New Thrombolytic 3 Plus international acute myocardial infarction pre-hospital care survey. European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20040601
Admission fibrinolytic profile predicts clot lysis resistance in stroke patients treated with tissue plasminogen activator. Thrombosis and haemostasis 20040601
Subretinal recombinant tissue plasminogen activator injection and pneumatic displacement of thick submacular hemorrhage in Age-Related macular degeneration. Ophthalmology 20040601
Effect of clopidogrel on tissue-plasminogen activator-induced in vitro thrombolysis of feline whole blood thrombi. American journal of veterinary research 20040601
Efficacy of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: one-year follow-up results of the Assessment of the Safety of a New Thrombolytic-3 (ASSENT-3) randomized trial in acute myocardial infarction. American heart journal 20040601
Protonation state of a single histidine residue contributes significantly to the kinetics of the reaction of plasminogen activator inhibitor-1 with tissue-type plasminogen activator. The Journal of biological chemistry 20040528
Strategies for fed-batch cultivation of t-PA producing CHO cells: substitution of glucose and glutamine and rational design of culture medium. Journal of biotechnology 20040527
[Diagnostic and therapeutic progress. Venous thromboembolism, cardiac insufficiency and radio contrast agents]. Presse medicale (Paris, France : 1983) 20040522
Trial application of a Model of Resource Utilization, Costs, and Outcomes for Stroke (MORUCOS) to assist priority setting in stroke. Stroke 20040501
Reducing hemostatic activation during cardiopulmonary bypass: a combined approach. Anesthesia and analgesia 20040501
Peroxynitrite inactivates tissue plasminogen activator. Anesthesia and analgesia 20040501
Association of the timing of ST-segment resolution with TIMI myocardial perfusion grade in acute myocardial infarction. American heart journal 20040501
ST-segment analyses and residual thrombi in the infarct-related artery: a report from the ASSENT PLUS ST-monitoring substudy. American heart journal 20040501
[Stability of postoperative visual acuity after rt-PA -SF6-treatment of submacular hemorrhage in age-related macular degeneration]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20040501
Differences in the regulation of BDNF and NGF synthesis in cultured neonatal rat astrocytes. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20040501
Successful recanalization of an occluded coronary artery by percutaneous coronary intervention, systemic administration of tirofiban, a glycoprotein IIb/IIIa inhibitor, and intracoronary thrombolysis with alteplase. Zeitschrift fur Kardiologie 20040501
[Study on correlation of insulin resistance with TCM syndrome type and activity of fibrinolytic system in patients with coronary arterial disease]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040501
[The ht-PAm cDNA knock-in the goat beta-casein gene locus]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040501
Association of a pulsatile blood flow pattern on coronary arteriography and short-term clinical outcomes in acute myocardial infarction. Journal of the American College of Cardiology 20040407
Evidence for disrupted NMDA receptor function in tissue plasminogen activator knockout mice. Behavioural brain research 20040402
Essential role of endogenous tissue plasminogen activator through matrix metalloproteinase 9 induction and expression on heparin-produced cerebral hemorrhage after cerebral ischemia in mice. Blood 20040401
Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator. Journal of pineal research 20040401
Impact of highly purified urinary FSH and recombinant FSH on haemostasis: an open-label, randomized, controlled trial. Human reproduction (Oxford, England) 20040401
Retinal toxicity of intravitreal tenecteplase in the rabbit. The British journal of ophthalmology 20040401
Association between obesity and a prothrombotic state: the Framingham Offspring Study. Thrombosis and haemostasis 20040401
Effectiveness of tirofiban for failed thrombolysis during acute myocardial infarction. The American journal of cardiology 20040401
Relationship between the door-to-TIMI-3 flow time and the infarct size in patients suffering from acute myocardial infarction: analysis based on the fibrinolysis and subsequent transluminal (FAST-3) trial. Circulation journal : official journal of the Japanese Circulation Society 20040401
Therapeutic yield and outcomes of a community teaching hospital code stroke protocol. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20040401
Facilitated percutaneous coronary intervention versus primary percutaneous coronary intervention: design and rationale of the Facilitated Intervention with Enhanced Reperfusion Speed to Stop Events (FINESSE) trial. American heart journal 20040401
Is tissue-type plasminogen activator a neuromodulator? Molecular and cellular neurosciences 20040401
The role of bradykinin in the antifibrotic actions of perindoprilat on human mesangial cells. Kidney international 20040401
SSR182289A enhances thrombolysis induced by fibrinolytic agents in rabbit models of venous and arterial thrombosis. Journal of thrombosis and haemostasis : JTH 20040401
Regulation of expression of tissue plasminogen activator and plasminogen activator inhibitor-1 by dichloroacetic acid in human fibroblasts from normal peritoneum and adhesions. American journal of obstetrics and gynecology 20040401
Extension of ischemic therapeutic time window by a free radical scavenger, Edaravone, reperfused with tPA in rat brain. Neurological research 20040401
Intravenously administered recombinant tissue-plasminogen activator attenuates neuronal injury after mild focal cerebral ischemia in mice. Neuroreport 20040322
The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release. Proceedings of the National Academy of Sciences of the United States of America 20040309
The transcription factor HACA mediates the unfolded protein response in Aspergillus niger, and up-regulates its own transcription. Molecular genetics and genomics : MGG 20040301
Systemic thrombolysis with recombinant tissue plasminogen activator and tirofiban in acute middle cerebral artery occlusion. Stroke 20040301
Purification and molecular cloning of a novel serine protease from the centipede, Scolopendra subspinipes mutilans. Insect biochemistry and molecular biology 20040301
Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system. Thrombosis and haemostasis 20040301
Both lysine-clusters of the NH2-terminal prion-protein fragment PrP23-110 are essential for t-PA mediated plasminogen activation. Thrombosis and haemostasis 20040301
Enhancement of endogenous fibrinolysis does not reduce local fibrin deposition, but modulates inflammation upon intestinal ischemia and reperfusion. Thrombosis and haemostasis 20040301
The fibrinolytic system attenuates vascular tone: effects of tissue plasminogen activator (tPA) and aminocaproic acid on renal microcirculation. British journal of pharmacology 20040301
Effects of nicorandil on endogenous fibrinolytic capacity in patients with coronary artery disease. Circulation journal : official journal of the Japanese Circulation Society 20040301
[The serine proteases and their function in neuronal death processes]. Revista de neurologia 20040301
Equivocal roles of tissue-type plasminogen activator in stroke-induced injury. Trends in neurosciences 20040301
[The management for macular edema]. Nippon Ganka Gakkai zasshi 20040301
Immunohistochemical localization of tissue-type plasminogen activator and type I plasminogen activator inhibitor in radicular cysts. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20040301
[Intra-arterial thrombolysis in basilar artery thrombosis. Recovery of two patients with locked-in syndrome]. Revista medica de Chile 20040301
Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction. Circulation 20040224
[Catheter-directed thrombolysis of iliofemoral venous thrombosis]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20040219
Improved speed and stability of ST-segment recovery with reduced-dose tenecteplase and eptifibatide compared with full-dose tenecteplase for acute ST-segment elevation myocardial infarction. Journal of the American College of Cardiology 20040218
19F NMR studies of plasminogen activator inhibitor-1. Biochemistry 20040217
Genetic and plasma markers of venous thromboembolism in patients with high grade glioma. Clinical cancer research : an official journal of the American Association for Cancer Research 20040215
Expression of trypsin-like proteases and protease nexin-1 in mdx mouse muscles. Biochemical and biophysical research communications 20040206
In vitro and in vivo effects of tPA and PAI-1 on blood vessel tone. Blood 20040201
Activity of an enzyme converting single-chain tissue-type plasminogen activator to the two-chain form in preovulatory human follicular fluid. Molecular reproduction and development 20040201
Periodontal disease and biomarkers related to cardiovascular disease. Journal of dental research 20040201
Questioning a class effect: does ACE inhibitor tissue penetration influence the degree of fibrinolytic balance alteration following an acute myocardial infarction? Journal of clinical pharmacology 20040201
Advances in stroke 2003: introduction. Stroke 20040201
Emerging therapies for cerebrovascular disorders. Stroke 20040201
Comparison of reperfusion regimens with or without tirofiban in ST-elevation acute myocardial infarction. The American journal of cardiology 20040201
Tissue plasminogen activator antigen and coronary heart disease. Prospective study and meta-analysis. European heart journal 20040201
CASE 1--2004. Intraoperative diagnosis of a patent foramen ovale in a patient undergoing coronary artery bypass graft surgery. Journal of cardiothoracic and vascular anesthesia 20040201
Plasminogen interaction with Trypanosoma cruzi. Memorias do Instituto Oswaldo Cruz 20040201
Intra-arterial injection of dissolved flunitrazepam tablets. VASA. Zeitschrift fur Gefasskrankheiten 20040201
Interactions between fibrinolysis, lipoproteins and leptin related to a first myocardial infarction. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20040201
Short-term intravenous eptifibatide infusion combined with reduced dose recombinant tissue plasminogen activator inhibits platelet recruitment at sites of coronary artery injury. Journal of the American College of Cardiology 20040121
Involvement of the plasminogen activation system in cow endometritis. Theriogenology 20040115
Predicting major neurological improvement with intravenous recombinant tissue plasminogen activator treatment of stroke. Stroke 20040101
Effect of the angiotensin II receptor blocker candesartan on fibrinolysis in patients with mild hypertension. Diabetes, obesity & metabolism 20040101
Intravitreal r-TPA and gas injection in traumatic submacular hemorrhage. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20040101
Benefits of direct angioplasty for women and men with acute myocardial infarction: results of the Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes Angioplasty (GUSTO II-B) Angioplasty Substudy. American heart journal 20040101
Clot penetration and fibrin binding of amediplase,a chimeric plasminogen activator (K2 tu-PA). Thrombosis and haemostasis 20040101
Surgical treatment of submacular hemorrhage in age-related macular degeneration. International ophthalmology clinics 20040101
Role of tissue-derived plasminogen activator (t-PA) in an excitotoxic mouse model of neonatal white matter lesions. Journal of neuropathology and experimental neurology 20040101
Short-term effects of exogenous angiotensin II on plasma fibrinolytic balance in normal subjects. Clinical and experimental hypertension (New York, N.Y. : 1993) 20040101
Angiotensin-converting enzyme insertion/deletion polymorphism modulates coronary release of tissue plasminogen activator in response to bradykinin. Hypertension research : official journal of the Japanese Society of Hypertension 20040101
New perspectives on the pharmacotherapy of ischemic stroke. Journal of the American Pharmacists Association : JAPhA 20040101
Vitamin E improves fibrinolytic activity in patients with coronary spastic angina. Thrombosis research 20040101
Effects of epsilon-aminocaproiloaminoacids on the amidolytic activity of tissue plasminogen activator, urokinase and kallikrein. Acta poloniae pharmaceutica 20040101
[Systemic thrombosis in central retinal artery occlusion--case report]. Oftalmologia (Bucharest, Romania : 1990) 20040101
[First experience of clopidogrel application in the treatment of acute myocardial infarction with ST-elevation]. Terapevticheskii arkhiv 20040101
Eprosartan effect on fibrinolytic/hemostatic variables in arterial hypertension: a comparative study to losartan. Drugs under experimental and clinical research 20040101
Changes in thrombolytic and inflammatory markers after initiation of indinavir- or amprenavir-based antiretroviral therapy. Cardiovascular toxicology 20040101
Beta2-glycoprotein I, anti-beta2-glycoprotein I, and fibrinolysis. Thrombosis research 20040101
Reperfusion treatment of ST-elevation acute myocardial infarction. Progress in cardiovascular diseases 20040101
Mechanism of the stimulatory effect of native fucoidan, highly sulfated fucoidan and heparin on plasminogen activation by tissue plasminogen activator: the role of chloride. European journal of drug metabolism and pharmacokinetics 20040101
[Migraine, inflammation, genes. New risk factors for stroke]. MMW Fortschritte der Medizin 20031218
Impact of time to treatment on mortality after prehospital fibrinolysis or primary angioplasty: data from the CAPTIM randomized clinical trial. Circulation 20031209
Plasminogen-mediated group A streptococcal adherence to and pericellular invasion of human pharyngeal cells. Microbial pathogenesis 20031201
Specific elevation in plasma tissue plasminogen activator antigen concentrations in South Asians relative to Europeans. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20031201
High D-dimer levels predict cardiovascular events in patients with chronic atrial fibrillation during oral anticoagulant therapy. Thrombosis and haemostasis 20031201
Safety and tolerability of abciximab in patients with acute myocardial infarction and failed thrombolysis. International journal of cardiology 20031201
Current perspectives on reperfusion therapy for acute ST-segment elevation myocardial infarction: integrating pharmacologic and mechanical reperfusion strategies. American heart journal 20031201
L-arginine improves endothelial vasoreactivity and reduces thrombogenicity after thrombolysis in experimental deep venous thrombosis. Journal of vascular surgery 20031201
Plasma tissue-type plasminogen activator, fibrinogen, and time on dialysis prior to transplantation are related to carotid intima media thickness in renal transplant recipients. Transplantation proceedings 20031201
Intravitreal tissue plasminogen activator in the management of central retinal vein occlusion. Retina (Philadelphia, Pa.) 20031201
Intravitreous recombinant tissue plasminogen activator and gas to treat submacular hemorrhage in age-related macular degeneration. The Kaohsiung journal of medical sciences 20031201
Modulation of PAI-1 and tPA activity and thrombolytic effects of corilagin. Planta medica 20031201
Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk? Clinical endocrinology 20031201
Hepatic clearance of tissue-type plasminogen activator and plasma kallikrein in experimental liver fibrosis. Liver international : official journal of the International Association for the Study of the Liver 20031201
Distortion of the catalytic domain of tissue-type plasminogen activator by plasminogen activator inhibitor-1 coincides with the formation of stable serpin-proteinase complexes. The Journal of biological chemistry 20031128
Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein. The Journal of clinical investigation 20031115
uPA, tPA and PAI-1 mRNA expression in periretinal membranes. Current eye research 20031101
Protective role of tuftsin fragment 1-3 in an animal model of intracerebral hemorrhage. Annals of neurology 20031101
Is there evidence of implicit exclusion criteria for elderly subjects in randomized trials? Evidence from the GUSTO-1 study. American heart journal 20031101
Intracoronary beta2 receptor activation induces dynamic local t-PA release in the pig. Thrombosis and haemostasis 20031101
Selective intraarterial fibrinolysis of acute central retinal artery occlusion. Acta radiologica (Stockholm, Sweden : 1987) 20031101
[Experiment study of infusing tPA in retinal vein for treatment of retinal vein occlusion]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20031101
[Neurological complication due to the drug and the maneuver for the treatment and prevention of cerebrovascular diseases: iatrogenic neurology]. Rinsho shinkeigaku = Clinical neurology 20031101
[Advances in the diagnosis and treatment of cerebral ischemia during the acute phase]. Rinsho shinkeigaku = Clinical neurology 20031101
Glycation induces formation of amyloid cross-beta structure in albumin. The Journal of biological chemistry 20031024
Effects of statins on nonlipid serum markers associated with cardiovascular disease: a systematic review. Annals of internal medicine 20031021
Endothelial cell adhesion to the fibronectin CS5 domain in artificial extracellular matrix proteins. Biomaterials 20031001
Urokinase type plasminogen activator receptor is involved in insulin-like growth factor-induced migration of rhabdomyosarcoma cells in vitro. Journal of cellular physiology 20031001
Are patients with acutely recovered cerebral ischemia more unstable? Stroke 20031001
Vitamin C affects thrombosis/ fibrinolysis system and reactive hyperemia in patients with type 2 diabetes and coronary artery disease. Diabetes care 20031001
Genetic deletion of tissue-type plasminogen activator (t-PA) in APOE3-Leiden mice reduces progression of cholesterol-induced atherosclerosis. Thrombosis and haemostasis 20031001
Outcome of urgent and elective percutaneous coronary interventions after pharmacologic reperfusion with tenecteplase combined with unfractionated heparin, enoxaparin, or abciximab. Journal of the American College of Cardiology 20031001
Confusion in reperfusion. Journal of the American College of Cardiology 20031001
Extracellular matrix degradation by cultured mesangial cells: mediators and modulators. Experimental biology and medicine (Maywood, N.J.) 20031001
Evaluation of minimally invasive therapies and rationale for a prospective randomized trial to evaluate selective intra-arterial lysis for clinically complete central retinal artery occlusion. Archives of ophthalmology (Chicago, Ill. : 1960) 20031001
Insulin resistance, hemostatic factors, and hormone interactions in pre- and perimenopausal women: SWAN. The Journal of clinical endocrinology and metabolism 20031001
Serum myoglobin/carbonic anhydrase III ratio as a marker of reperfusion after myocardial infarction. International journal of cardiology 20031001
Risk of intracranial haemorrhage with combined fibrinolytic and glycoprotein IIb/IIIa inhibitor therapy in acute myocardial infarction. Dichotomous response as a function of age in the GUSTO V trial. European heart journal 20031001
Successful thrombolysis of submassive pulmonary embolism after bariatric surgery: expanding the indications and addressing the controversies. Obesity surgery 20031001
Identification and characterization of novel lysine-independent apolipoprotein(a)-binding sites in fibrin(ogen) alphaC-domains. The Journal of biological chemistry 20030926
Interactions of fibrinolytic system proteins with lysine-containing surfaces. Journal of biomedical materials research. Part A 20030915
Plasminogen activator/plasmin system regulates formation of the hepatocyte spheroids. Biochemical and biophysical research communications 20030905
Acute and chronic effects of oestrogen on endothelial tissue-type plasminogen activator release in postmenopausal women. The Journal of physiology 20030901
Persistent poststroke hyperglycemia is independently associated with infarct expansion and worse clinical outcome. Stroke 20030901
Pitavastatin alters the expression of thrombotic and fibrinolytic proteins in human vascular cells. Journal of cellular biochemistry 20030901
Rosiglitazone inhibits the insulin-mediated increase in PAI-1 secretion in human abdominal subcutaneous adipocytes. Diabetes, obesity & metabolism 20030901
Positive impact of hormone replacement therapy on the fibrinolytic system: a long-term randomized controlled study in healthy postmenopausal women. Journal of thrombosis and haemostasis : JTH 20030901
Usefulness of prodromal unstable angina pectoris in predicting better survival and smaller infarct size in acute myocardial infarction (The InTIME-II Prodromal Symptoms Substudy). The American journal of cardiology 20030901
Prehospital thrombolysis with reteplase: the Nijmegen/Rotterdam study. American heart journal 20030901
Increased plasma levels of plasminogen activator inhibitor-1 and soluble vascular cell adhesion molecule after triacylglycerol infusion in man. Thrombosis and haemostasis 20030901
The effects of serine proteinase inhibitors on bone resorption in vitro. The Journal of endocrinology 20030901
[Treatment of acute stroke -- an overview]. Therapeutische Umschau. Revue therapeutique 20030901
[Antithrombotic effects of morpholine and piperazine ring derivatives and their molecular mechanism]. Yao xue xue bao = Acta pharmaceutica Sinica 20030901
Surgical treatments of central retinal vein occlusion. Seminars in ophthalmology 20030901
Beneficial effects of immediate stenting after thrombolysis in acute myocardial infarction. Journal of the American College of Cardiology 20030820
Absence of tissue plasminogen activator gene or activity impairs mouse cerebellar motor learning. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030813
[Facilitated revascularisation in myocardial infarction with ST-segment elevation]. Orvosi hetilap 20030810
Glycoprotein IIb/IIIa receptor antagonist (2S)-2-[(2-Naphthyl-sulfonyl)amino]-3-[[2-([4-(4-piperidinyl)-2-[2-(4-piperidinyl)ethyl] butanoyl]amino)acetyl]amino]propanoic acid dihydrochloride (CRL42796), in combination with aspirin and/or enoxaparin, prevents coronary artery rethrombosis after successful thrombolytic treatment by recombinant tissue plasminogen activator. The Journal of pharmacology and experimental therapeutics 20030801
Thrombolysis with recombinant tissue plasminogen activator and tirofiban in stroke: preliminary observations. Stroke 20030801
Effect of benazepril amlodipine combination on fibrinolysis in hypertensive diabetic patients. European journal of clinical pharmacology 20030801
Differences in clot preparation determine outcome of recombinant tissue plasminogen activator treatment in experimental thromboembolic stroke. Stroke 20030801
Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion. Stroke 20030801
Increased Interleukin-6 levels in pituitary-deficient patients are independently related to their carotid intima-media thickness. Clinical endocrinology 20030801
Expression and regulation of plasminogen activators, plasminogen activator inhibitor type-1, and steroidogenic acute regulatory protein in the rhesus monkey corpus luteum. Endocrinology 20030801
Evaluation of lipoprotein(a) as a prothrombotic factor: progress from bench to bedside. Current opinion in lipidology 20030801
The role of platelets and platelet inhibition in acute myocardial infarction. Coronary artery disease 20030801
Circulating t-PA antigen predicts major adverse coronary events in patients with stable coronary artery disease--a 13-year follow-up. Thrombosis and haemostasis 20030801
No alteration in platelet function or coagulation induced by EGb761 in a controlled study. Clinical and laboratory haematology 20030801
Structural determinants in the stability of the serpin/proteinase complex. Biochemical and biophysical research communications 20030801
Cardiac tamponade mimicking ventricular rupture after thrombolysis for acute myocardial infarction. Minerva cardioangiologica 20030801
Decrease of hemostatic cardiovascular risk factors by aggressive vs. conventional atorvastatin treatment in patients with Type 2 diabetes mellitus. Journal of thrombosis and haemostasis : JTH 20030801
[Evolution of fibrinolysis status with D-dimer level and the rate of plasminogen activator inhibitor type-1/D-dimer in acute coronary syndrome patients complicated with impaired glucose tolerance]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20030801
ST segment resolution in ASSENT 3: insights into the role of three different treatment strategies for acute myocardial infarction. European heart journal 20030801
Association study between Alzheimer's disease and genes involved in Abeta biosynthesis, aggregation and degradation: suggestive results with BACE1. Journal of neurology 20030801
All-trans retinoic acid modulates microvascular endothelial cell hemostatic properties. Haematologica 20030801
Selective activation of PPARgamma inhibits pancreatic cancer invasion and decreases expression of tissue plasminogen activator. Surgery 20030801
Expression pattern and functional studies of matrix degrading proteases and their inhibitors in the mouse corpus luteum. Molecular and cellular endocrinology 20030731
Efficacy and safety of tenecteplase in combination with the low-molecular-weight heparin enoxaparin or unfractionated heparin in the prehospital setting: the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT)-3 PLUS randomized trial in acute myocardial infarction. Circulation 20030715
Relation of levels of hemostatic factors and inflammatory markers to the ankle brachial index. The American journal of cardiology 20030715
Phospholipid-associated annexin A2-S100A10 heterotetramer and its subunits: characterization of the interaction with tissue plasminogen activator, plasminogen, and plasmin. The Journal of biological chemistry 20030711
Pericellular plasmin induces smooth muscle cell anoikis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701
Impaired explorative behavior and neophobia in genetically modified mice lacking or overexpressing the extracellular serine protease inhibitor neuroserpin. Molecular and cellular neurosciences 20030701
Angiographic and clinical characteristics associated with the development of Q-wave and non-Q-wave myocardial infarction in the thrombolysis in myocardial infarction (TIMI) 14 trial. American heart journal 20030701
The genetics of atherothrombotic disorders: a clinician's view. Journal of thrombosis and haemostasis : JTH 20030701
Thrombin-activatable fibrinolysis inhibitor (TAFI, plasma procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U). Journal of thrombosis and haemostasis : JTH 20030701
Inhibition of plasminogen activation by lipoprotein(a): critical domains in apolipoprotein(a) and mechanism of inhibition on fibrin and degraded fibrin surfaces. The Journal of biological chemistry 20030627
Inhibition of plasminogen activation protects against ganglion cell loss in a mouse model of retinal damage. Molecular vision 20030612
Endogenous proteolytic activity in a rat model of spontaneous cerebral stroke. Brain research 20030606
Urokinase potentiates PDGF-induced chemotaxis of human airway smooth muscle cells. American journal of physiology. Lung cellular and molecular physiology 20030601
Cardiac sympathetic nerve stimulation triggers coronary t-PA release. Arteriosclerosis, thrombosis, and vascular biology 20030601
Thrombolytic therapy with recombinant tissue plasminogen activator for acute ischemic stroke: where do we go from here? A cumulative meta-analysis. Stroke 20030601
Community-based thrombolytic therapy of acute ischemic stroke in Helsinki. Stroke 20030601
Plasma homocysteine and its relationships with atherothrombotic markers in psoriatic patients. Clinica chimica acta; international journal of clinical chemistry 20030601
Left intraventricular pressure gradient induced by cardiac tamponade after thrombolysis for acute myocardial infarction. International journal of cardiology 20030601
Relationships between activators and inhibitors of plasminogen, and the progression of small abdominal aortic aneurysms. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20030601
Amyloid endostatin induces endothelial cell detachment by stimulation of the plasminogen activation system. Molecular cancer research : MCR 20030601
Expression of RANK is dependent upon differentiation into the macrophage/osteoclast lineage: induction by 1alpha,25-dihydroxyvitamin D3 and TPA in a human myelomonocytic cell line, HL60. Bone 20030601
Thrombolysis of acute peripheral arterial and venous occlusions with tenecteplase and eptifibatide: a pilot study. Journal of vascular and interventional radiology : JVIR 20030601
Cryoprecipitate. Patterns of use. American journal of clinical pathology 20030601
High intakes of trans monounsaturated fatty acids taken for 2 weeks do not influence procoagulant and fibrinolytic risk markers for CHD in young healthy men. The British journal of nutrition 20030601
Managing hypertension in patients with stroke. Are you prepared for labetalol infusion? Critical care nurse 20030601
Absence of profound hyperinsulinism in polycystic ovary syndrome is associated with subtle elevations in the plasminogen activator inhibitor system. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030601
Intra-arterial tissue plasminogen activator for thrombosis complicating cerebral angiography in a 17-year-old girl. Journal of child neurology 20030601
New fibrinolytic agents: benzothiophene derivatives as inhibitors of the t-PA-PAI-1 complex formation. Bioorganic & medicinal chemistry letters 20030519
Inhibition of endothelial cell proliferation by the recombinant kringle domain of tissue-type plasminogen activator. Biochemical and biophysical research communications 20030516
Effects of admission hyperglycemia on stroke outcome in reperfused tissue plasminogen activator--treated patients. Stroke 20030501
Danger of treatment protocols. Stroke 20030501
Ethanol plus caffeine (caffeinol) for treatment of ischemic stroke: preclinical experience. Stroke 20030501
Pilot dose-escalation study of caffeine plus ethanol (caffeinol) in acute ischemic stroke. Stroke 20030501
Low molecular weight heparin (dalteparin) compared to unfractionated heparin as an adjunct to rt-PA (alteplase) for improvement of coronary artery patency in acute myocardial infarction-the ASSENT Plus study. European heart journal 20030501
Stimulation of plasminogen activation by recombinant cellular prion protein is conserved in the NH2-terminal fragment PrP23-110. Thrombosis and haemostasis 20030501
Suppression of argatroban-induced endogenous thrombolysis by PKSI-527, and antibodies to TPA and UPA, evaluated in a rat arterial thrombolysis model. Thrombosis and haemostasis 20030501
Double blind, randomized study of estradiol replacement therapy on markers of inflammation, coagulation and fibrinolysis. Atherosclerosis 20030501
Hyperglycemia and early reperfusion therapy. Stroke 20030501
Left ventricular function and cardiovascular events following adjuvant therapy with adenosine in acute myocardial infarction treated with thrombolysis, results of the ATTenuation by Adenosine of Cardiac Complications (ATTACC) study. European journal of clinical pharmacology 20030501
[Research on quantified diagnosis and combining diseases with syndrome of blood stasis]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20030501
Combination reperfusion therapy with eptifibatide and reduced-dose tenecteplase for ST-elevation myocardial infarction: results of the integrilin and tenecteplase in acute myocardial infarction (INTEGRITI) Phase II Angiographic Trial. Journal of the American College of Cardiology 20030416
Angiotensin-converting enzyme inhibition but not angiotensin II type 1 receptor antagonism augments coronary release of tissue plasminogen activator in hypertensive patients. Journal of the American College of Cardiology 20030416
Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415
In vitro comparison of complementary interactions between synthetic linear/branched oligo/poly-L-lysines and tissue plasminogen activator by means of high-performance monolithic-disk affinity chromatography. Journal of chromatography. A 20030411
Comparison between the effects of mixed dyslipidaemia and hypercholesterolaemia on endothelial function, atherosclerotic lesions and fibrinolysis in rabbits. Clinical science (London, England : 1979) 20030401
An 89-year-old woman with angioedema during t-PA infusion for acute ischemic stroke. Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20030401
Tissue plasminogen activator and NMDA receptor cleavage. Nature medicine 20030401
Effect of tenecteplase versus alteplase on platelets during the first 3 hours of treatment for acute myocardial infarction: the Assessment of the Safety and Efficacy of a New Thrombolytic Agent (ASSENT-2) platelet substudy. American heart journal 20030401
Retinal toxicity of intravitreal tissue plasminogen activator: case report and literature review. Ophthalmology 20030401
Intra-arterial tumor necrosis factor-alpha impairs endothelium-dependent vasodilatation and stimulates local tissue plasminogen activator release in humans. Arteriosclerosis, thrombosis, and vascular biology 20030401
The effect of fucoidan, heparin and cyanogen bromide-fibrinogen on the activation of human glutamic-plasminogen by tissue plasminogen activator. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030401
[Coronary atherosclerosis and vascular endothelial dysfunction]. Nihon rinsho. Japanese journal of clinical medicine 20030401
[Anti thrombotic therapy after coronary thrombolysis]. Nihon rinsho. Japanese journal of clinical medicine 20030401
Hemostatic variables, carbohydrate metabolism and lipid profile in women with low body mass index. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030401
Cellular mechanisms of the hemostatic effects of desmopressin (DDAVP). Journal of thrombosis and haemostasis : JTH 20030401
Management of acute stroke. Southern medical journal 20030401
Serine proteases of the fibrinolysis pathway are not involved in lethal hepatitis and fibrinogen breakdown induced by tumor necrosis factor. Cytokine 20030321
Effects of inhibition of P2Y(1) and P2Y(12) on whole blood clotting, coagulum elasticity and fibrinolysis resistance studied with free oscillation rheometry. Thrombosis research 20030315
Stabilization versus inhibition of TAFIa by competitive inhibitors in vitro. The Journal of biological chemistry 20030314
Kindling status in sprague-dawley rats induced by pentylenetetrazole: involvement of a critical development period. The American journal of pathology 20030301
Candida albicans binds human plasminogen: identification of eight plasminogen-binding proteins. Molecular microbiology 20030301
Sustained ventricular arrhythmias and mortality among patients with acute myocardial infarction: results from the GUSTO-III trial. American heart journal 20030301
New insights into the tPA-annexin A2 interaction. Is annexin A2 CYS8 the sole requirement for this association? The Journal of biological chemistry 20030221
Angiotensin-converting enzyme inhibition increases human vascular tissue-type plasminogen activator release through endogenous bradykinin. Circulation 20030204
Transforming growth factor alpha-induced expression of type 1 plasminogen activator inhibitor in astrocytes rescues neurons from excitotoxicity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201
Tissue plasminogen activator in the amygdala is critical for stress-induced anxiety-like behavior. Nature neuroscience 20030201
Thrombolysis for acute stroke. Current opinion in neurology 20030201
Relationship between fibrinolytic activity and gingival inflammatory reaction in young individuals. Journal of periodontal research 20030201
Sex hormone metabolism in prostate cancer cells during transition to an androgen-independent state. The Journal of clinical endocrinology and metabolism 20030201
Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration. Stroke 20030201
Fibrinolytic capacity increases with age in healthy humans, while endothelium-dependent vasodilation is unaffected. Thrombosis and haemostasis 20030201
Endothelial dysfunction after arterial thrombosis is ameliorated by L-arginine in combination with thrombolysis. Journal of vascular and interventional radiology : JVIR 20030201
Advantages of fast-acting ADP receptor blockade in ischemic heart disease. Arteriosclerosis, thrombosis, and vascular biology 20030201
Blockade of the platelet P2Y12 receptor by AR-C69931MX sustains coronary artery recanalization and improves the myocardial tissue perfusion in a canine thrombosis model. Arteriosclerosis, thrombosis, and vascular biology 20030201
Reduced brain infarct volume and improved neurological outcome by inhibition of the NR2B subunit of NMDA receptors by using CP101,606-27 alone and in combination with rt-PA in a thromboembolic stroke model in rats. Journal of neurosurgery 20030201
[Experimental microvascular and clotting changes--significance for acute stroke therapy]. Der Nervenarzt 20030201
Prediction of 24 h, nonfatal complications in patients with acute myocardial infarction receiving thrombolytic therapy by calculation of the ST segment deviation score. The Canadian journal of cardiology 20030201
Myocardial infarction and primary thrombocytosis in a young man. Acta cardiologica 20030201
Acute systemic inflammation enhances endothelium-dependent tissue plasminogen activator release in men. Journal of the American College of Cardiology 20030115
Role of plasminogen activators during healing after uterine serosal lesioning in the rat. Fertility and sterility 20030101
Relationship between high plasma leptin concentrations and metabolic syndrome in obese pre-pubertal children. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20030101
Reactive hyperemia and tissue-type plasminogen activator release in hypertensive men. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030101
Pre-thrombotic state and impaired fibrinolytic potential in coronary heart disease patients with left ventricular dysfunction. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030101
Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury. Neuroscience 20030101
Antithrombotic drug treatment of pediatric patients with ischemic stroke. Paediatric drugs 20030101
[The best of thrombosis in 2002]. Archives des maladies du coeur et des vaisseaux 20030101
Decreased neural damage after spinal cord injury in tPA-deficient mice. Journal of neurotrauma 20030101
Multiple enzymatic digestion for enhanced sequence coverage of proteins in complex proteomic mixtures using capillary LC with ion trap MS/MS. Journal of proteome research 20030101
Use of abciximab and tirofiban in patients with peripheral arterial occlusive disease and arterial thrombosis. Angiology 20030101
Effects of argatroban and heparin on thrombus formation and tissue plasminogen activator-induced thrombolysis in a microvascular thrombosis model. Thrombosis research 20030101
Local intra-arterial fibrinolysis in acute hemispheric stroke: effect of occlusion type and fibrinolytic agent on recanalization success and neurological outcome. Cerebrovascular diseases (Basel, Switzerland) 20030101
Effects of octreotide on epidermal growth factor receptor, tissue plasminogen activator, and plasminogen activator inhibitor during intraperitoneal adhesion formation. Journal of gastroenterology 20030101
Acetylsalicylic acid pretreatment, concomitant heparin therapy and the risk of early intracranial hemorrhage following systemic thrombolysis for acute ischemic stroke. Cerebrovascular diseases (Basel, Switzerland) 20030101
Intravitreal tissue plasminogen activator for the treatment of central retinal vein occlusion. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20030101
[Selected new atherosclerosis risk factors and markers of fibrinolysis in children and adolescents with obesity, hypertension and diabetes]. Przeglad lekarski 20030101
Modulation of fibrinolytic system components in mesothelial cells by hyaluronan. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20030101
[Treatment of subretinal macular hemorrhages with intravitreous injections of tissue plasminogen activator and SF6 gas]. Klinika oczna 20030101
[Effect of diet therapy on status of hemocoagulation and fibrinolysis in type 2 diabetes patients]. Voprosy pitaniia 20030101
Medical management of patients with an acute stroke: treatment and prevention. Topics in stroke rehabilitation 20030101
Expression of type-1 plasminogen activator inhibitor in the kidney of diabetic rat models. Thrombosis research 20030101
Thrombolytic treatment of portal thrombosis. Hepato-gastroenterology 20030101
Analysis of factors influencing the blood levels and activities of tissue-type plasminogen activator (t-PA). Clinical hemorheology and microcirculation 20030101
Mechanism of the stimulatory effect of 6-aminohexanoic acid on plasminogen activation by streptokinase or tissue plasminogen activator: the role of chloride. European journal of drug metabolism and pharmacokinetics 20030101
Double bolus of 0.75 MU streptokinase plus enoxaparin versus front-loaded alteplase plus unfractionated heparin in ST-segment elevation myocardial infarction. Romanian journal of internal medicine = Revue roumaine de medecine interne 20030101
Proteases involved in long-term potentiation. Life sciences 20021220
TGF-beta1 increases tyrosine hydroxylase expression by a mechanism blocked by BMP-2 in human neuroblastoma SH-SY5Y cells. Brain research 20021220
Acyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitro. The Journal of biological chemistry 20021206
Maspin inhibits cell migration in the absence of protease inhibitory activity. The Journal of biological chemistry 20021206
Ozonized autohaemotransfusion and fibrinolytic balance in peripheral arterial occlusive disease. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20021201
The value of the TIMI frame count method in the diagnosis of coronary no-reflow: a comparison with myocardial perfusion SPECT in patients with acute myocardial infarction. Nuclear medicine communications 20021201
ACE inhibition versus angiotensin type 1 receptor antagonism: differential effects on PAI-1 over time. Hypertension (Dallas, Tex. : 1979) 20021201
Cryptogenic stroke in relation to genetic variation in clotting factors and other genetic polymorphisms among young men and women. Stroke 20021201
Thrombolytic treatment of clot embolism in rat: comparison of intra-arterial and intravenous application of recombinant tissue plasminogen activator. Stroke 20021201
Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis. Molecular and cellular neurosciences 20021201
Management of submacular hemorrhage. Ophthalmology clinics of North America 20021201
[Impact of intravenous thrombolysis prior to percutaneous coronary intervention in reperfusion therapy for acute myocardial infarction]. Journal of cardiology 20021201
[Pleiotropic effects of micronized fenofibrate in patients with combined hyperlipidemia]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20021201
Quantitative evaluation of the influence of ovarian steroids on plasminogen activators and inhibitors in human endometrial cells and trophoblasts. Thrombosis research 20021125
Collagen dissolution by keratinocytes requires cell surface plasminogen activation and matrix metalloproteinase activity. The Journal of biological chemistry 20021122
Mechanisms of conversion of plasminogen activator inhibitor 1 from a suicide inhibitor to a substrate by monoclonal antibodies. The Journal of biological chemistry 20021115
Ca2+ -regulated secretion of tissue-type plasminogen activator and von Willebrand factor in human endothelial cells. Biochimica et biophysica acta 20021104
Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering. Kidney international 20021101
Time lag to diagnosis of stroke in children. Pediatrics 20021101
Association between increased homocysteine levels and impaired fibrinolytic potential: potential mechanism for cardiovascular risk. Thrombosis and haemostasis 20021101
Thyroid-stimulating hormone induces interleukin-18 gene expression in FRTL-5 cells: immunohistochemical detection of interleukin-18 in autoimmune thyroid disease. Thyroid : official journal of the American Thyroid Association 20021101
Veno-occlusive disease of the liver after blood and marrow transplantation: analysis of pre- and post-transplant risk factors associated with severity and results of therapy with tissue plasminogen activator. Leukemia & lymphoma 20021101
Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism. The New England journal of medicine 20021010
A concerted structural transition in the plasminogen activator inhibitor-1 mechanism of inhibition. Biochemistry 20021008
t-PA in CRVO. Ophthalmology 20021001
Sustained benefits of metformin therapy on markers of cardiovascular risk in human immunodeficiency virus-infected patients with fat redistribution and insulin resistance. The Journal of clinical endocrinology and metabolism 20021001
A combined treatment with tacrolimus (FK506) and recombinant tissue plasminogen activator for thrombotic focal cerebral ischemia in rats: increased neuroprotective efficacy and extended therapeutic time window. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20021001
Complete recovery after early intraarterial recombinant tissue plasminogen activator thrombolysis of carotid T occlusion. AJNR. American journal of neuroradiology 20021001
Treatment of central retinal vein occlusion by vitrectomy with lysis of vitreopapillary and epipapillary adhesions, subretinal peripapillary tissue plasminogen activator injection, and photocoagulation. American journal of ophthalmology 20021001
The local chromaffin cell plasminogen/plasmin system and the regulation of catecholamine secretion. Annals of the New York Academy of Sciences 20021001
Chromaffin cell plasminogen receptors. Annals of the New York Academy of Sciences 20021001
[Value of eptifibatide during salvage angioplasty with coronary stenting after failure of thrombolysis. Report of a series of 41 patients]. Archives des maladies du coeur et des vaisseaux 20021001
Variations in lipoprotein levels after myocardial infarction and unstable angina: the LATIN trial. Italian heart journal : official journal of the Italian Federation of Cardiology 20021001
Thrombocytosis and recurrent hepatic outflow obstruction (Budd-Chiari syndrome) after successful thrombolysis: case report and literature review. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20021001
Patient outcomes after fibrinolytic therapy for acute myocardial infarction at hospitals with and without coronary revascularization capability. Journal of the American College of Cardiology 20020918
PKCalpha-mediated ERK, JNK and p38 activation regulates the myogenic program in human rhabdomyosarcoma cells. Journal of cell science 20020915
Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke Trial. Neurology 20020910
Marked bradykinin-induced tissue plasminogen activator release in patients with heart failure maintained on long-term angiotensin-converting enzyme inhibitor therapy. Journal of the American College of Cardiology 20020904
Biphasic regulation of plasminogen activator/inhibitor by LDL in mesangial cells. American journal of physiology. Renal physiology 20020901
Additional evidence that the sympathetic nervous system regulates the vessel wall release of tissue plasminogen activator. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20020901
Is diabetic hypercoagulability an acquired annexinopathy? Glycation of annexin II as a putative mechanism for impaired fibrinolysis in diabetic patients. Medical hypotheses 20020901
Spitz naevi may express components of the plasminogen activation system. The Journal of pathology 20020901
Intravenous recombinant tissue-type plasminogen activator thrombolysis in treatment of central retinal artery occlusion. Archives of ophthalmology (Chicago, Ill. : 1960) 20020901
Recurrent peripheral arterial thrombosis induced by cisplatin and etoposide. Pharmacotherapy 20020901
Prognosis of central retinal artery occlusion: local intraarterial fibrinolysis versus conservative treatment. AJNR. American journal of neuroradiology 20020901
Tissue plasminogen activator plus gas injection in patients with subretinal hemorrhage caused by age-related macular degeneration: predictive variables for visual outcome. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20020901
Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells. Journal of neurochemistry 20020901
Smoking is associated with altered endothelial-derived fibrinolytic and antithrombotic factors: an in vitro demonstration. Circulation 20020820
Plasminogen activator-plasmin system potentiates the proliferation of hepatocytes in primary culture. Thrombosis research 20020815
Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke. Circulation 20020806
Increased fibrinogen, von Willebrand factor and tissue plasminogen activator levels in insulin resistant South Asian patients with ischaemic stroke. Atherosclerosis 20020801
Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration. Cell death and differentiation 20020801
Intra-atrial thrombolytic therapy for dissolution of chronic left atrial thrombi in patients undergoing balloon mitral commissurotomy. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020801
Tissue factor pathway inhibitor and other endothelium-dependent hemostatic factors in elderly individuals with normal or impaired glucose tolerance and type 2 diabetes. Diabetes care 20020801
Modulation of tissue plasminogen activator and plasminogen activator inhibitor-1 by transforming growth factor-beta in human retinal glial cells. Investigative ophthalmology & visual science 20020801
Epidermal expression of serine protease, neuropsin (KLK8) in normal and pathological skin samples. Molecular pathology : MP 20020801
Enhancement of t-PA-mediated plasminogen activation by partially defucosylated glycosaminoglycans from the sea cucumber Stichopus japonicus. Journal of biochemistry 20020801
Predictors of hemorrhagic transformation after intravenous recombinant tissue plasminogen activator: prognostic value of the initial apparent diffusion coefficient and diffusion-weighted lesion volume. Stroke 20020801
[A case of renal infarction treated by thrombolytic therapy with systemic intravenous injection of tPA (tissue plasminogen activator)]. Hinyokika kiyo. Acta urologica Japonica 20020801
Tissue plasminogen activator is required for corticostriatal long-term potentiation. The European journal of neuroscience 20020801
Quantitative measurement of carotid atherosclerosis in relation to levels of von Willebrand factor and fibrinolytic variables in plasma--a 2-year follow-up study. Journal of cardiovascular risk 20020801
The ratio of plasminogen activator inhibitor type-1 activity to the concentration of plasminogen activator inhibitor type-1 protein in diabetes: adding insult to injury. Coronary artery disease 20020801
Regular alcohol intake and fibrinolysis. The Netherlands journal of medicine 20020801
Images in cardiology: Worm-shaped thrombus mimicking Chiari's network in a cocaine user. Heart (British Cardiac Society) 20020701
A specific elevation in tissue plasminogen activator antigen in women with polycystic ovarian syndrome. The Journal of clinical endocrinology and metabolism 20020701
Relationship of tissue plasminogen activator, plasminogen activator inhibitor-1 and fibrinogen with coronary artery disease in South Indian male subjects. The Journal of the Association of Physicians of India 20020701
Cellular activation responses in blood in relation to lipid pattern: healthy men and women in families with myocardial infarction or cancer. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20020701
[Intravitreal injection of rt-PA and gas in the management of minor submacular haemorrhages secondary to age-related macular degeneration]. Klinische Monatsblatter fur Augenheilkunde 20020701
Spinal epidural hematoma following tissue plasminogen activator and heparinization for acute myocardial infarction. Japanese heart journal 20020701
Selected amino acids protect hybridoma and CHO cells from elevated carbon dioxide and osmolality. Biotechnology and bioengineering 20020630
Controlled shear affinity filtration (CSAF): a new technology for integration of cell separation and protein isolation from mammalian cell cultures. Biotechnology and bioengineering 20020630
Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent. The Journal of clinical investigation 20020615
Plasminogen activation is stimulated by prion protein and regulated in a copper-dependent manner. Biochemistry 20020604
Tissue factor and tissue factor pathway inhibitor levels in unstable angina patients during short-term low-molecular-weight heparin administration. British journal of haematology 20020601
The impact of angiotensin II receptor blockade and the DASH diet on markers of endogenous fibrinolysis. Journal of human hypertension 20020601
Effects of the spin trap agent disodium- [tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit Large clot embolic stroke model: combination studies with tissue plasminogen activator. Stroke 20020601
Biochemical basis of angioedema associated with recombinant tissue plasminogen activator treatment: an in vitro experimental approach. Stroke 20020601
Thyroid follicular cells secrete plasminogen activators and can form angiostatin from plasminogen. The Journal of endocrinology 20020601
Ethnicity affects vasodilation, but not endothelial tissue plasminogen activator release, in response to bradykinin. Arteriosclerosis, thrombosis, and vascular biology 20020601
Tenecteplase: new preparation. Another thrombolytic agent for myocardial infarction: a slightly simpler treatment. Prescrire international 20020601
The effects of early insulin treatment combined with thrombolysis in rat embolic stroke. Neurological research 20020601
Function of tissue-type plasminogen activator releaser on vascular endothelial cells and thrombolysis in vivo. Thrombosis and haemostasis 20020601
Cirrhosis does not shift the circadian phase of plasma fibrinolysis. The American journal of gastroenterology 20020601
Tissue-type plasminogen activator (t-PA) is stored in Weibel-Palade bodies in human endothelial cells both in vitro and in vivo. Blood 20020515
Reduced expression of endothelial cell markers after 1 year treatment with simvastatin and atorvastatin in patients with coronary heart disease. Atherosclerosis 20020501
Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020501
tPA and gas in submacular hemorrhage. Ophthalmology 20020501
Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator. Stroke 20020501
Effect of all-trans-retinoic acid on the hypercoagulable state of patients with breast cancer. American journal of hematology 20020501
Re: Nonlocalized lower gastrointestinal bleeding: provocative bleeding studies with intraarterial tPA, heparin, and tolazoline. Journal of vascular and interventional radiology : JVIR 20020501
Thrombolysis for acute ischemic stroke: still a treatment for the few by the few. The Western journal of medicine 20020501
New aspects in thrombosis research: possible role of mast cells as profibrinolytic and antithrombotic cells. Thrombosis and haemostasis 20020501
Expression of urokinase plasminogen activator receptor in resting and activated bovine neutrophils. The Journal of dairy research 20020501
The p11 subunit of annexin II heterotetramer is regulated by basic carboxypeptidase. Biochemistry 20020416
Plasminogen activator activity in cortical granules of bovine oocytes during in vitro maturation. Theriogenology 20020415
Absence of paradoxical thrombin activation by fibrin-specific thrombolytics in acute myocardial infarction: comparison of single-bolus tenecteplase and front-loaded alteplase. Thrombosis research 20020415
Enoxaparin as adjunctive antithrombin therapy for ST-elevation myocardial infarction: results of the ENTIRE-Thrombolysis in Myocardial Infarction (TIMI) 23 Trial. Circulation 20020409
Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey. Circulation 20020409
Oncostatin M induces tissue-type plasminogen activator and plasminogen activator inhibitor-1 in Calu-1 lung carcinoma cells. Cytokine 20020407
Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: progressive, interrelated, and independently associated with risk of death. Diabetes 20020401
Regulation of plasminogen activator inhibitor-1 secretion by urokinase and tissue plasminogen activator in rat epithelioid-type smooth muscle cells. British journal of haematology 20020401
Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator. Development (Cambridge, England) 20020401
Tissue plasminogen activator, fibrin D-dimer, and insulin resistance in the relatives of patients with premature coronary artery disease. Arteriosclerosis, thrombosis, and vascular biology 20020401
Cholesterol emboli syndrome occurring after administration of tissue plasminogen activator. Journal of the Mississippi State Medical Association 20020401
Local proCPU (TAFI) activation during thrombolytic treatment in a dog model of coronary artery thrombosis can be inhibited with a direct, small molecule thrombin inhibitor (melagatran). Thrombosis and haemostasis 20020401
Tissue plasminogen activator as a key effector in neurobiology and neuropathology. Biochemical Society transactions 20020401
Tissue plasminogen activator as a modulator of neuronal survival and function. Biochemical Society transactions 20020401
Hemostasis imbalance in experimental hypertension. Molecular medicine (Cambridge, Mass.) 20020401
Bradykinin enhances in vitro procoagulant and antifibrinolytic properties of rat vascular endothelial cells. Thrombosis research 20020401
Arsenic trioxide, retinoic acid and Ara-c regulated the expression of annexin II on the surface of APL cells, a novel co-receptor for plasminogen/tissue plasminogen activator. Thrombosis research 20020401
Direct tissue plasminogen activator administration through a microinjection device in a pig model of retinal vein thrombosis. Current eye research 20020401
Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020315
Thrombolytic therapy reduces red blood cell aggregation in plasma without affecting intrinsic aggregability. Thrombosis research 20020315
A structural and dynamic investigation of the facilitating effect of glycoprotein IIb/IIIa inhibitors in dissolving platelet-rich clots. Circulation research 20020308
Platelets inhibit the lysis of pulmonary microemboli. American journal of physiology. Lung cellular and molecular physiology 20020301
Using a peptide inhibitor of the glycoprotein IIb/IIIa platelet receptor: initial experience in patients with acute peripheral arterial occlusions. AJR. American journal of roentgenology 20020301
Pituitary adenylate cyclase-activating polypeptide modulates plasminogen activator expression in rat granulosa cell. Biology of reproduction 20020301
Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis. Stroke 20020301
Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats. Stroke 20020301
Changes in the fibrinolytic system during angiography with ionic and with nonionic contrast media. Academic radiology 20020301
Smoking impairs bradykinin-stimulated t-PA release. Hypertension (Dallas, Tex. : 1979) 20020301
Pharmacology advances in the neuroscience intensive care unit. Critical care nursing clinics of North America 20020301
Myocardial ischemia induces coronary t-PA release in the pig. Acta anaesthesiologica Scandinavica 20020301
[Analysis of gene complexes predisposing to coronary atherosclerosis]. Genetika 20020301
[Pilot study of the effectiveness of combination therapy with reduced dose alteplase and the glycoprotein IIb/IIIa antagonist tirofiban in acute myocardial infarct]. Zeitschrift fur Kardiologie 20020301
Stimulated release of endothelin-converting enzyme is simultaneous with tissue-type plasminogen activator and decrease in coronary heart disease. Scandinavian cardiovascular journal : SCJ 20020301
The management of stroke patients by neurologists: common questions and new observations. Seminars in neurology 20020301
Thrombolysis and hemorrhagic transformation. Stroke 20020301
Patient safety in trials of therapy for acute ischemic stroke. JAMA 20020227
Enhanced secretion of tissue plasminogen activator by simultaneous use of retinoic acid and ascorbic acid from tissue cultured gastroepiploic artery. Life sciences 20020208
Eptifibatide and low-dose tissue plasminogen activator in acute myocardial infarction: the integrilin and low-dose thrombolysis in acute myocardial infarction (INTRO AMI) trial. Journal of the American College of Cardiology 20020206
Plasminogen activator inhibitor-1 in girls with precocious pubarche: a premenarcheal marker for polycystic ovary syndrome? Pediatric research 20020201
Plasminogen activating capacity in gingival fluid from deteriorating and stable periodontal pockets. Journal of periodontal research 20020201
Alteplase use for prevention of central line occlusion in a preterm infant. The Annals of pharmacotherapy 20020201
Improved fibrinolysis after one year of treatment with enalapril in men and women with uncomplicated myocardial infarction. Thrombosis and haemostasis 20020201
Pharmacodynamic effects of oral contraceptive steroids on biochemical markers for arterial thrombosis. Studies in non-diabetic women and in women with insulin-dependent diabetes mellitus. Danish medical bulletin 20020201
Primary intracoronary stenting in comparison with intravenous rt-PA thrombolysis plus rescue intracoronary intervention in patients with acute myocardial infarction. Chinese medical journal 20020201
Comparative effects of estrogen and angiotensin-converting enzyme inhibition on plasminogen activator inhibitor-1 in healthy postmenopausal women. Circulation 20020122
Tissue plasminogen activator is required for striatal post-ischemic synaptic potentiation. Neuroreport 20020121
Two naturally occurring variants of TAFI (Thr-325 and Ile-325) differ substantially with respect to thermal stability and antifibrinolytic activity of the enzyme. The Journal of biological chemistry 20020111
Thrombolysis for acute myocardial infarction: drug review. MedGenMed : Medscape general medicine 20020102
Hypercholesterolaemia and lipid lowering treatment do not affect the acute endogenous fibrinolytic capacity in vivo. Heart (British Cardiac Society) 20020101
The nonpeptide glycoprotein IIb/IIIa platelet receptor antagonist SM-20302 reduces tissue plasminogen activator-induced intracerebral hemorrhage after thromboembolic stroke. Stroke 20020101
Treating subretinal hemorrhage with tissue plasminogen activator. Archives of ophthalmology (Chicago, Ill. : 1960) 20020101
Cytokine-induced expression of tPA is differentially modulated by NO and ROS in rat mesangial cells. Kidney international 20020101
HMG CoA reductase inhibitors affect the fibrinolytic system of human vascular cells in vitro: a comparative study using different statins. British journal of pharmacology 20020101
Future of neuroprotective drugs in doubt. Nature medicine 20020101
Plasminogen activator inhibitor-1 induction after experimental intracerebral hemorrhage. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020101
Clomethiazole: an unsuccessful bachelor, but perhaps a prosperous married man? Stroke 20020101
Lekteplase--a secreted tissue plasminogen activator derivative from Escherichia coli. Arzneimittel-Forschung 20020101
Decrease of fibrinolytic activity in human endothelial cells by arsenite. Thrombosis research 20020101
Hyperglycemia in patients with focal cerebral ischemia after intravenous thrombolysis: influence on clinical outcome and infarct size. Cerebrovascular diseases (Basel, Switzerland) 20020101
Clinical implications of urokinase and tissue type plasminogen activators and their inhibitor (PAI-1) in breast cancer tissue. Oncology reports 20020101
[Effect of chronic administration of epaden and acetylsalicylic acid on the antithrombotic potential of blood vessel walls in rabbits]. Eksperimental'naia i klinicheskaia farmakologiia 20020101
[Cerebral vasospasm after subarachnoid hemorrhage. Current possibilities of prevention and treatment]. Przeglad lekarski 20020101
Effects of a long-term pharmacological interruption of the renin-angiotensin system on the fibrinolytic system in essential hypertension. Pathophysiology of haemostasis and thrombosis 20020101
The effect of chronic allograft rejection on plasma regulators of fibrinolysis. Annals of transplantation 20020101
Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. Molecular cancer 20020101
Hemostasis and fibrinolysis factors in first-degree relatives of patients with Type 2 diabetes without hypertension. Pathophysiology of haemostasis and thrombosis 20020101
Fibrinolysis defect in long-term hemodialysis patients with type 2 diabetes mellitus and its relation to metabolic disorders. American journal of nephrology 20020101
Successful thrombolysis of st. Jude medical aortic prosthesis with tissue-type plasminogen activator in a pregnant woman: a case report. Cardiology in review 20020101
Venous port salvage utilizing low dose tPA. Cardiovascular and interventional radiology 20020101
Prognostic significance of tissue-type plasminogen activator (tPA) content in gastric cancer and surrounding mucosa. The International journal of biological markers 20020101
Amediplase: CGP 42935, K2tu-PA, MEN 9036. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20020101
Effect of spironolactone on impaired fibrinolysis of hypertensive patients. Kidney & blood pressure research 20020101
[Study on interventing effect of puerarin on insulin resistance in patients with coronary heart disease]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020101
Study on the mechanism of the annexin II-mediated co-assembly of t-PA and plasminogen. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101
Cell adhesion induces the plasminogen activator inhibitor-1 gene expression through phosphatidylinositol 3-kinase/Akt activation in anchorage dependent cells. Cell communication & adhesion 20020101
[Degradation of streptokinase and the catalytic properties of the plasmin-streptokinase complex]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101
Neuritogenesis and the nerve growth factor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin generation. The Journal of biological chemistry 20011228
New thrombolytic regimens in acute myocardial infarction. Lancet (London, England) 20011215
Plasminogen activation without changes in tPA and PAI-1 in response to subcutaneous administration of ancrod. Thrombosis research 20011215
Acute stroke care in non-urban emergency departments. Neurology 20011211
Ensuring patient safety in clinical trials for treatment of acute stroke. JAMA 20011205
Risk factors of ischaemic heart disease and long-term outcome after coronary bypass surgery. The Journal of cardiovascular surgery 20011201
[Infiltrating ductal carcinomas of the breast in women over 60 years of age. Association with higher cellular proliferation and lower PS2, cell surface and cytosolic hyaluronic acid concentrations]. Revista espanola de medicina nuclear 20011201
Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein IIb/IIIa inhibitor: report of four cases. Radiology 20011201
Injection of tissue plasminogen activator into a branch retinal vein in eyes with central retinal vein occlusion. Ophthalmology 20011201
Disintegration and reorganization of fibrin networks during tissue-type plasminogen activator-induced clot lysis. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20011201
Mean transit times and the sites of synthesis and catabolism of tissue plasminogen activator and plasminogen activator inhibitor type 1 in young subjects. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20011201
Systematic elucidation of effects of tranexamic acid on fibrinolysis and bleeding during and after cardiopulmonary bypass surgery. Thrombosis research 20011201
Postischemic (6-Hour) treatment with recombinant human tissue plasminogen activator and proteasome inhibitor PS-519 reduces infarction in a rat model of embolic focal cerebral ischemia. Stroke 20011201
Effects of fibrates on plasma prothrombotic activity in patients with type IIb dyslipidemia. International journal of clinical pharmacology and therapeutics 20011201
Acute stroke management. Canadian family physician Medecin de famille canadien 20011201
[Using enzymes in the posterior eye segment. Current status and future possibilities]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20011201
[Strategy for circulatory disturbance]. Rinsho shinkeigaku = Clinical neurology 20011201
[Diagnosis and treatment of brain stem infarction]. Rinsho shinkeigaku = Clinical neurology 20011201
Induction of hepatic tissue-type plasminogen activator and type 1 plasminogen activator-inhibitor gene expressions and appearance of their translation products in the bile following acute liver injury in rats. Thrombosis research 20011115
Losartan inhibits the angiotensin II-induced modifications on fibrinolysis and matrix deposition by primary human vascular smooth muscle cells. Journal of cardiovascular pharmacology 20011101
Method to measure in vivo blood fibrinolytic activity with a (125)I-fibrin coated aorta loop validated with agents which affect blood fibrinolytic activity. Thrombosis research 20011101
Evidence for impairment of behavioural inhibition in performance of operant tasks in tPA-/- mice. Behavioural brain research 20011101
Short-term effects of transdermal nicotine on acute tissue plasminogen activator release in vivo in man. Cardiovascular research 20011101
Potentiation of bradykinin-induced tissue plasminogen activator release by angiotensin-converting enzyme inhibition. Journal of the American College of Cardiology 20011101
Extension of the therapeutic window for recombinant tissue plasminogen activator with argatroban in a rat model of embolic stroke. Stroke 20011101
Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: role of hemodynamic alterations. Stroke 20011101
Nonlocalized lower gastrointestinal bleeding: provocative bleeding studies with intraarterial tPA, heparin, and tolazoline. Journal of vascular and interventional radiology : JVIR 20011101
Safety and efficacy of limited-dose tissue plasminogen activator in acute vascular occlusion. Journal of vascular surgery 20011101
Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chemistry & biology 20011101
DRL performance in mice with deletion of tPA, uPA or PAI-1 genes. Behavioural pharmacology 20011101
Expression of mRNA for plasminogen activators and protease nexin-1 in innervated and denervated mouse skeletal muscle. Journal of neuroscience research 20011101
Elimination of hydrocortisone from the medium enables tissue plasminogen activator gene expression by normal and immortalized nonmalignant human epithelial cells. Biological chemistry 20011101
[Plasminogen activators (t-PA and u-PA) and other fibrinolysis parameters in patients with atherosclerosis obliterans and diabetic macroangiopathy]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20011101
Glucose-based optimization of CHO-cell perfusion cultures. Biotechnology and bioengineering 20011020
IL-1beta down-regulates tissue-type plasminogen activator by up-regulating low-density lipoprotein receptor-related protein in AML 12 cells. Biochemical and biophysical research communications 20011019
The Clomethiazole Acute Stroke Study in tissue-type plasminogen activator-treated stroke (CLASS-T): final results. Neurology 20011009
Comparison of the effects of O2*-/HO* free radical- and copper ions-oxidized LDL or lipoprotein(a) on the endothelial cell releases of tissue plasminogen activator and plasminogen activator inhibitor-1. Life sciences 20011005
Pharmacokinetic studies of Gln117 tissue-type plasminogen activator in rats. Journal of pharmaceutical and biomedical analysis 20011001
Reciprocal regulation of tissue-type and urokinase-type plasminogen activators in the differentiation of murine preadipocyte line 3T3-L1 and the hormonal regulation of fibrinolytic factors in the mature adipocytes. Journal of cellular physiology 20011001
[Clinical-biological characteristics of infiltrating ductal carcinomas of the breast with estrogen receptor concentrations >300 fmol/mg protein]. Revista espanola de medicina nuclear 20011001
The effect of thrombolytic therapy on left ventricular aneurysm formation in acute myocardial infarction: relationship to successful reperfusion and vessel patency. Clinical cardiology 20011001
Low-dose tissue plasminogen activator followed by planned rescue angioplasty reduces time to reperfusion for acute myocardial infarction treated at community hospitals. Japanese circulation journal 20011001
The effect of vasodilators on aspirin-induced antagonism of t-PA thrombolysis. Neurological research 20011001
Thrombolytic treatment for thrombosis of a mitral valve prosthesis during pregnancy. Intensive care medicine 20011001
Increased reperfusion by glycoprotein IIb/IIIa receptor antagonist administration in case of unsuccessful and failed thrombolysis in patients with acute myocardial infarction: a pilot study. Italian heart journal : official journal of the Italian Federation of Cardiology 20011001
Beneficial effects of diltiazem during myocardial reperfusion: a randomized trial in acute myocardial infarction. Italian heart journal : official journal of the Italian Federation of Cardiology 20011001
Concurrent use of reteplase and lepirudin in the treatment of acute anterior wall myocardial infarction. Journal of thrombosis and thrombolysis 20011001
Effect of ionic and nonionic contrast media on fibrinolysis in patients undergoing angiocardiography. The Kaohsiung journal of medical sciences 20011001
The fibrinolytic system in chronic renal failure. European journal of medical research 20010928
Alcohol consumption and hemostatic factors: analysis of the Framingham Offspring cohort. Circulation 20010918
Expression of neural plasticity related gene in the pontine tegmental area of rats with overactive bladder after cerebral infarction. The Journal of urology 20010901
Production of tissue plasminogen activator (t-PA) in Aspergillus niger. Biotechnology and bioengineering 20010901
Adjunctive therapies in the cath lab. Combination of tirofiban and alteplase in acute myocardial infarction. The Journal of invasive cardiology 20010901
A simple and rapid laboratory method for determination of haemostasis potential in plasma. II. Modifications for use in routine laboratories and research work. Thrombosis research 20010901
Effect of progesterone on the invasive properties and tumor growth of progesterone receptor-transfected breast cancer cells MDA-MB-231. Clinical cancer research : an official journal of the American Association for Cancer Research 20010901
Hypersensitivity reactions associated with recombinant tissue-type plasminogen activator and urokinase. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20010901
Plasmin-independent gelatinase B (matrix metalloproteinase-9) release by monocytes under the influence of urokinase. Biochemistry. Biokhimiia 20010901
Differentiation of human dopamine neurons from an embryonic carcinomal stem cell line. Brain research 20010831
Efficacy and safety of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: the ASSENT-3 randomised trial in acute myocardial infarction. Lancet (London, England) 20010825
Predictors of good outcome after intravenous tPA for acute ischemic stroke. Neurology 20010814
Randomized comparison of enoxaparin, a low-molecular-weight heparin, with unfractionated heparin adjunctive to recombinant tissue plasminogen activator thrombolysis and aspirin: second trial of Heparin and Aspirin Reperfusion Therapy (HART II). Circulation 20010807
[Study of the cytosolic concentrations of the tissue poly-peptide specific (TPS) antigen in infiltrating ductal carcinomas of the breast. Positive relationship with hormone dependency and negative with cellular proliferation]. Revista espanola de medicina nuclear 20010801
Intravitreous injection of tissue plasminogen activator and gas in the treatment of submacular hemorrhage under various conditions. Ophthalmology 20010801
A randomized trial confirming the efficacy of reduced dose recombinant tissue plasminogen activator in a Chinese myocardial infarction population and demonstrating superiority to usual dose urokinase: the TUCC trial. American heart journal 20010801
Nimodipine increases fibrinolytic activity in patients with aneurysmal subarachnoid hemorrhage. Stroke 20010801
Antithrombotic efficacy of a novel factor Xa inhibitor, FXV673, in a canine model of coronary artery thrombolysis. British journal of pharmacology 20010801
Increased levels of tissue plasminogen activator antigen and factor VIII activity in nonvalvular atrial fibrillation: relation to predictors of thromboembolism. Journal of cardiovascular electrophysiology 20010801
The production of improved tissue-type plasminogen activator in Escherichia coli. Seminars in thrombosis and hemostasis 20010801
[Central retinal artery occlusion. Importance of selective intra-arterial fibrinolysis]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20010801
[Optimal thrombolysis]. Zeitschrift fur Kardiologie 20010801
Safety and efficacy of thrombolysis with alteplase (50 mg) plus tirofiban versus alteplase (100 mg) alone in acute myocardial infarction: preliminary findings. Italian heart journal : official journal of the Italian Federation of Cardiology 20010801
Controlled release of clot-dissolving tissue-type plasminogen activator from a poly(L-glutamic acid) semi-interpenetrating polymer network hydrogel. Journal of controlled release : official journal of the Controlled Release Society 20010710
In vitro preparation and ellipsometric characterization of thin blood plasma clot films on silicon. Biomaterials 20010701
Combined effect of retinoic acid and basic FGF on PAI-1 gene expression in vascular smooth muscle cells. Cardiovascular research 20010701
Control of mouse cumulus cell-oocyte complex integrity before and after ovulation: plasminogen activator synthesis and matrix degradation. Endocrinology 20010701
No Influence of acute hypertriglyceridemia on plasma t-PA in healthy male volunteers. Thrombosis research 20010701
Metformin reduces weight, centripetal obesity, insulin, leptin, and low-density lipoprotein cholesterol in nondiabetic, morbidly obese subjects with body mass index greater than 30. Metabolism: clinical and experimental 20010701
Low-dose retinoic acid enhances in vitro invasiveness of human oral squamous-cell-carcinoma cell lines. British journal of cancer 20010701
A family of novel, acidic N-glycans in Bowes melanoma tissue plasminogen activator have L2/HNK-1-bearing antennae, many with sulfation of the fucosylated chitobiose core. European journal of biochemistry 20010701
The expression of plasminogen activator system in a rat model of periodontal wound healing. Journal of periodontology 20010701
Tissue- and urokinase-type plasminogen activators and type 1 plasminogen activator inhibitor in melanomas and benign skin pigment neoplasms. Bulletin of experimental biology and medicine 20010701
Biological profiles in subjects with recurrent acute coronary events compared with subjects with long-standing stable angina. Circulation 20010626
Too much, too little, or none at all: dealing with substandard and fake drugs. Lancet (London, England) 20010616
Reperfusion therapy for acute myocardial infarction with fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein IIb/IIIa inhibition: the GUSTO V randomised trial. Lancet (London, England) 20010616
Comparison of effects of losartan versus enalapril on fibrinolysis and coagulation in patients with acute myocardial infarction. The American journal of cardiology 20010615
Conversion of Glu-plasminogen to Lys-plasminogen is necessary for optimal stimulation of plasminogen activation on the endothelial cell surface. The Journal of biological chemistry 20010601
Antithrombotic and fibrinolytic system of human endothelial cells seeded on PTFE: the effects of surface modification of PTFE by ammonia plasma treatment and ECM protein coatings. Biomaterials 20010601
Circulating levels of plasminogen activator inhibitor type-1, tissue plasminogen activator, and thrombomodulin in hemodialysis patients: biochemical correlations and role as independent predictors of coronary artery stenosis. Journal of the American Society of Nephrology : JASN 20010601
Chronic disseminated intravascular coagulation after surgery for abdominal aortic aneurysm: clinical and haemostatic response to dalteparin. British journal of haematology 20010601
Treatment of subretinal hemorrhages with tissue plasminogen activator. Current opinion in ophthalmology 20010601
Use of tissue plasminogen activator to revive blebs following intraocular surgery. Archives of ophthalmology (Chicago, Ill. : 1960) 20010601
Increased levels of tPA antigen and tPA/PAI-1 complex in myotonic dystrophy. Journal of internal medicine 20010601
Fibrin specificity of plasminogen activators, rebound generation of thrombin, and their therapeutic implications. Coronary artery disease 20010601
Adenovirus-mediated expression and packaging of tissue-type plasminogen activator in megakaryocytic cells. Thrombosis and haemostasis 20010601
[Effectiveness of locoregional rt-PA lysis in acute leg and arm vein thrombosis]. Zentralblatt fur Chirurgie 20010601
Fluorescent multiplex polymerase chain reaction analysis of four genes associated with inpaired fibrinolysis and myocardial infarction. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20010601
Treatment of deep cerebral venous thrombosis by local infusion of tissue plasminogen activator. Surgical neurology 20010601
Tissue-type plasminogen activator is involved in the process of neuronal death induced by oxygen-glucose deprivation in culture. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010601
Tissue-type plasminogen activator and plasminogen activator inhibitor type-1 mRNA and their protein expression levels in human decidua after early pregnancy termination by mifepristone plus misoprostol. Chinese medical journal 20010601
Bleeding complications associated with the use of rt-PA versus r-PA for peripheral arterial and venous thromboembolic occlusions. Techniques in vascular and interventional radiology 20010601
[Inhibition of cultured human retinal pigment epithelial cell by tissue-type plasminogen activator]. Yan ke xue bao = Eye science 20010601
Binding of plasminogen and tissue plasminogen activator to plasmin-modulated factor X and factor Xa. Biochemistry 20010529
Pregnancy zone protein-tissue-type plasminogen activator complexes bind to low-density lipoprotein receptor-related protein (LRP). Archives of biochemistry and biophysics 20010515
Functional evaluation of plasmin formation in primary breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010515
Haemostasis in relation to dietary fat as estimated by erythrocyte fatty acid composition: the prime study. Thrombosis research 20010515
Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids. The Journal of biological chemistry 20010511
Sonic hedgehog and FGF8: inadequate signals for the differentiation of a dopamine phenotype in mouse and human neurons in culture. Experimental neurology 20010501
Lower-dose heparin with fibrinolysis is associated with lower rates of intracranial hemorrhage. American heart journal 20010501
Insulin resistance and elevated levels of tissue plasminogen activator in first-degree relatives of South Asian patients with ischemic cerebrovascular disease. Stroke 20010501
Bradykinin stimulates the release of tissue plasminogen activator in human coronary circulation: effects of angiotensin-converting enzyme inhibitors. Journal of the American College of Cardiology 20010501
Superiority of enoxaparin over heparin in combination with a GPIIb/IIIa receptor antagonist during coronary thrombolysis in dogs. Thrombosis research 20010501
Elucidation of the binding regions of PAI-1 neutralizing antibodies using chimeric variants of human and rat PAI-1. Thrombosis and haemostasis 20010501
Extracellular nucleotides ATP and UTP induce a marked acute release of tissue-type plasminogen activator in vivo in man. Thrombosis and haemostasis 20010501
Beta-lactam antibiotic-mediated changes in platelet reactivity and vascular endothelial functions. Pharmacology & toxicology 20010501
Decreased tissue plasminogen activator and increased plasminogen activator inhibitors and increased activator protein-1 and specific promoter 1 are associated with inhibition of invasion in human A375 melanoma deprived of tyrosine and phenylalanine. International journal of oncology 20010401
Early computed tomography hypodensity predicts hemorrhage after intravenous tissue plasminogen activator in acute ischemic stroke. Journal of neuroimaging : official journal of the American Society of Neuroimaging 20010401
Noninvasive transcutaneous low frequency ultrasound enhances thrombolysis in peripheral and coronary arteries. Echocardiography (Mount Kisco, N.Y.) 20010401
Polymorphonuclear leucocytes mediate endogenous thrombus lysis via a u-PA-dependent mechanism. British journal of haematology 20010401
[Usefulness of combination therapy of hybrid thrombolysis followed by back-up percutaneous transluminal coronary angioplasty in patients with acute myocardial infarction]. Journal of cardiology 20010401
Binding of recombinant apolipoprotein(a) to human platelets and effect on platelet aggregation. Thrombosis and haemostasis 20010401
[GPIIb/IIIa blockers for optimizing thrombolysis in acute myocardial infarct]. Herz 20010401
Combination of early and delayed SPET imaging using technetium-99m ethyl cysteinate dimer immediately after local intra-arterial thrombolysis. European journal of nuclear medicine 20010401
Thrombin converts singlet oxygen (1O2)-oxidized fibrinogen into a soluble t-PA cofactor. A new method for preparing a stimulator for functional t-PA assays. Annals of hematology 20010401
The hemostatic effects of warfarin titration in post CABG patients in comparison to placebo treatment. Journal of thrombosis and thrombolysis 20010401
Serotonin induces the expression of tissue factor and plasminogen activator inhibitor-1 in cultured rat aortic endothelial cells. Blood 20010315
MSP, a trypsin-like serine protease, is abundantly expressed in the human nervous system. The Journal of comparative neurology 20010312
Matrix metalloproteinase-1 and -9 activation by plasmin regulates a novel endothelial cell-mediated mechanism of collagen gel contraction and capillary tube regression in three-dimensional collagen matrices. Journal of cell science 20010301
Tissue plasminogen activator protects hippocampal neurons from oxygen-glucose deprivation injury. Journal of neuroscience research 20010301
Intravitreal injection of tissue plasminogen activator: four considerations. Archives of ophthalmology (Chicago, Ill. : 1960) 20010301
Plasminogen activators direct reorganization of the liver lobule after acute injury. The American journal of pathology 20010301
Clinical deterioration following improvement in the NINDS rt-PA Stroke Trial. Stroke 20010301
Effect of valsartan on angiotensin II-induced plasminogen activator inhibitor-1 biosynthesis in arterial smooth muscle cells. Hypertension (Dallas, Tex. : 1979) 20010301
Influence of sugar chain on fibrin affinity of recombinant t-PA. Biological & pharmaceutical bulletin 20010301
Effects of human tissue plasminogen gene transfer on allograft coronary atherosclerosis. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20010301
[Efficacy of low-dose mutant tissue-type plasminogen activator followed by planned rescue percutaneous transluminal coronary angioplasty as reperfusion therapy for acute myocardial infarction]. Journal of cardiology 20010301
Epsilon-aminocaproic acid promotes the release of alpha2-antiplasmin during and after cardiopulmonary bypass. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20010301
Oxygen modulates the release of urokinase and plasminogen activator inhibitor-1 by retinal pigment epithelial cells. The international journal of biochemistry & cell biology 20010301
Stimulation of plasminogen activator activity and matrix metalloproteinases of human dental pulp-derived cells by tumor necrosis factor-alpha. Journal of endodontics 20010301
Hyperinsulinemia and hemostatic abnormalities are associated with silent lacunar cerebral infarcts in elderly hypertensive subjects. Journal of the American College of Cardiology 20010301
Methylazoximethanol acetate-induced cell death in the granule cell layer of the developing mouse cerebellum is associated with caspase-3 activation, but does not depend on the tissue-type plasminogen activator. Neuroscience letters 20010216
Regulation of plasminogen binding to neutrophils. Blood 20010215
Fibrinolytic parameters and insulin resistance in young survivors of myocardial infarction with heterozygous familial hypercholesterolemia. Wiener klinische Wochenschrift 20010215
Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II). Stroke 20010201
Components of the fibrinolytic system are differently altered in moderate and severe hypothyroidism. The Journal of clinical endocrinology and metabolism 20010201
Increased PAI-1 and tPA antigen levels are reduced with metformin therapy in HIV-infected patients with fat redistribution and insulin resistance. The Journal of clinical endocrinology and metabolism 20010201
A novel synthetic inhibitor of factor Xa decreases early reocclusion and improves 24-h patency after coronary fibrinolysis in dogs. The Journal of pharmacology and experimental therapeutics 20010201
Nicotine induced changes in gene expression by human coronary artery endothelial cells. Atherosclerosis 20010201
Effects of acute methionine loading and vitamin C on endogenous fibrinolysis, endothelium-dependent vasomotion and platelet aggregation. Clinical science (London, England : 1979) 20010201
Fibrinolytic response to acute exercise in patients with peripheral arterial disease. Medicine and science in sports and exercise 20010201
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Combination Therapy Stroke Trial: recombinant tissue-type plasminogen activator with/without lubeluzole. Cerebrovascular diseases (Basel, Switzerland) 20010101
Intravitreous tissue plasminogen activator injection and pneumatic displacement in the management of submacular hemorrhage complicating scleral buckling procedures. Retina (Philadelphia, Pa.) 20010101
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Prosthetic heart valve thrombosis during dicloxacillin therapy. Scandinavian cardiovascular journal : SCJ 19990101
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Cocaine-induced myocardial infarction: treatment with thrombolytic therapy. Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 19950401
Ligand binding to the tissue-type plasminogen activator kringle 2 domain: structural characterization by 1H-NMR. Biochemistry 19950307
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A case of acute myocardial infarction. Intracoronary thrombosis in two major coronary arteries due to hormone therapy. Angiology 19940501
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Changes of the fibrinolytic system in liver dysfunction: role of portal hypertension. Thrombosis research 19920701
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Heparin selectively inhibits the transcription of tissue-type plasminogen activator in primate arterial smooth muscle cells during mitogenesis. The Journal of biological chemistry 19920215
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Inhibition by dexamethasone of the reperfusion phenomena in cardiopulmonary bypass. The Journal of thoracic and cardiovascular surgery 19911001
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Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors. Journal of internal medicine 19910201
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Suppression of estrogen-regulated extracellular tissue plasminogen activator activity of MCF-7 cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer research 19871201
Amiloride selectively inhibits the urokinase-type plasminogen activator. FEBS letters 19870406
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