Home Halogens 2-[(3-chloro-2-methylphenyl)amino]pyridine-3-carboxylic acid

2-[(3-chloro-2-methylphenyl)amino]pyridine-3-carboxylic acid

CAS No.:
17737-65-4
Catalog Number:
AG0025A5
Molecular Formula:
C13H11ClN2O2
Molecular Weight:
262.6916
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$19
- +
5g
98%
In Stock USA
United States
$44
- +
25g
98%
In Stock USA
United States
$100
- +
100g
98%
In Stock USA
United States
$300
- +
Product Description
Catalog Number:
AG0025A5
Chemical Name:
2-[(3-chloro-2-methylphenyl)amino]pyridine-3-carboxylic acid
CAS Number:
17737-65-4
Molecular Formula:
C13H11ClN2O2
Molecular Weight:
262.6916
MDL Number:
MFCD00864292
IUPAC Name:
2-(3-chloro-2-methylanilino)pyridine-3-carboxylic acid
InChI:
InChI=1S/C13H11ClN2O2/c1-8-10(14)5-2-6-11(8)16-12-9(13(17)18)4-3-7-15-12/h2-7H,1H3,(H,15,16)(H,17,18)
InChI Key:
CLOMYZFHNHFSIQ-UHFFFAOYSA-N
SMILES:
OC(=O)c1cccnc1Nc1cccc(c1C)Cl
EC Number:
241-730-1
UNII:
V7DXN0M42R
NSC Number:
335505
Properties
Complexity:
301  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
262.051g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
262.693g/mol
Monoisotopic Mass:
262.051g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
62.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.8  
Literature
Title Journal
Differential Gene Expression across Breed and Sex in Commercial Pigs Administered Fenbendazole and Flunixin Meglumine. PloS one 20150101
Stimulatory effect of PGF2α on PRL based on experimental inhibition of each hormone in mares. Theriogenology 20121201
Evaluating a novel analgesic strategy for ring castration of ram lambs. Veterinary anaesthesia and analgesia 20120901
Direct effect of PGF2α pulses on PRL pulses, based on inhibition of PRL or PGF2α secretion in heifers. Theriogenology 20120801
Inhibition of prostaglandin biosynthesis during postluteolysis and effects on CL regression, prolactin, and ovulation in heifers. Theriogenology 20120715
Validation of a rapid lateral flow test for the simultaneous determination of β-lactam drugs and flunixin in raw milk. Journal of food protection 20120701
Comparison of the effects of IV administration of meloxicam, carprofen, and flunixin meglumine on prostaglandin E(2) concentration in aqueous humor of dogs with aqueocentesis-induced anterior uveitis. American journal of veterinary research 20120501
The effect of systemic administration of cloprostenol on ovulation in mares treated with a prostaglandin synthetase inhibitor. Reproduction in domestic animals = Zuchthygiene 20120201
Ultrasound characteristics of experimentally induced luteinized unruptured follicles (LUF) and naturally occurring hemorrhagic anovulatory follicles (HAF) in the mare. Theriogenology 20120201
Effects of adrenocorticotropic hormone and flunixin meglumine on pregnancy retention in beef cows. Journal of animal science 20120101
Anesthesia case of the month. EPAM. Journal of the American Veterinary Medical Association 20120101
[Determination of residual organic solvents in flunixin meglumine raw material by headspace gas chromatography]. Se pu = Chinese journal of chromatography 20120101
Effects of meloxicam and flunixin on pain, stress and discomfort in male piglets during and after surgical castration. Berliner und Munchener tierarztliche Wochenschrift 20120101
Therapeutic and adverse effects of flunixin-meglumine in adult and young cats. The Journal of veterinary medical science 20111201
Doping control in horses: housing conditions and oral recycling of flunixin by ingestion of contaminated straw. Journal of veterinary pharmacology and therapeutics 20111201
Effect of flunixin meglumine on the amelioration of lameness in dairy steers with amphotericin B-induced transient synovitis-arthritis. American journal of veterinary research 20111101
Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses. Equine veterinary journal. Supplement 20111101
The effects of two analgesic regimes on behavior after abdominal surgery in Steller sea lions. Veterinary journal (London, England : 1997) 20111001
Evaluation of the brain, renal, and hepatic effects of flunixin meglumine, ketoprofen, and phenylbutazone administration in Iranian fat-tailed sheep. Tropical animal health and production 20111001
Effects of inhibition of prostaglandin F2α biosynthesis during preluteolysis and luteolysis in heifers. Theriogenology 20110901
Effects of flunixin meglumine, recombinant bovine somatotropin and/or human chorionic gonadotropin on pregnancy rates in Nelore cows. Theriogenology 20110901
The effects of a novel anti-inflammatory compound (AHI-805) on cyclooxygenase enzymes and the recovery of ischaemia injured equine jejunum ex vivo. Equine veterinary journal. Supplement 20110801
Effects of flunixin meglumine on the recovery of ischaemic equine colonic mucosa in vitro. Equine veterinary journal. Supplement 20110801
The effect of treatment with flunixin meglumine at different times relative to hCG administration on ovulation failure and luteal function in mares. Animal reproduction science 20110801
Follicle and systemic hormone interrelationships during induction of luteinized unruptured follicles with a prostaglandin inhibitor in mares. Theriogenology 20110715
Comparison of the immunosuppressive effects of dexamethasone, flunixin meglumine and meloxicam on the in vitro response of calf peripheral blood mononuclear cells. The Journal of veterinary medical science 20110701
The effect of intramuscular injection of dinoprost or gonadotropin-releasing hormone in dairy cows on beef quality. Journal of animal science 20110601
Disruption of periovulatory FSH and LH surges during induced anovulation by an inhibitor of prostaglandin synthesis in mares. Animal reproduction science 20110601
First detection of an NSAID, flunixin, in sheep's wool using GC-MS. Environmental pollution (Barking, Essex : 1987) 20110501
Associations among behavioral and acute physiologic responses to lipopolysaccharide-induced clinical mastitis in lactating dairy cows. American journal of veterinary research 20110501
Analgesic effects of meloxicam, morphine sulfate, flunixin meglumine, and xylazine hydrochloride in African-clawed frogs (Xenopus laevis). Journal of the American Association for Laboratory Animal Science : JAALAS 20110501
Effects of non-steroidal anti-inflammatory drugs on proliferation, differentiation and migration in equine mesenchymal stem cells. Cell biology international 20110301
Systemic treatment with high dose of flunixin-meglumine is able to block ovulation in mares by inducing hemorrhage and luteinisation of follicles. Theriogenology 20110301
Effects of buprenorphine, meloxicam, and flunixin meglumine as postoperative analgesia in mice. Journal of the American Association for Laboratory Animal Science : JAALAS 20110301
Effects of acute hepatic and renal failure on pharmacokinetics of flunixin meglumine in rats. Experimental animals 20110101
Distribution of flunixin meglumine and firocoxib into aqueous humor of horses. Journal of veterinary internal medicine 20110101
GABAergic regulation of auditory sensory gating in low- and high-anxiety rats submitted to a fear conditioning procedure. Neuroscience 20101229
Practical experience with the treatment of recipient mares with a non-steroidal anti-inflammatory drug in an equine embryo transfer programme. Reproduction in domestic animals = Zuchthygiene 20101201
Hepatic effects of flunixin-meglumin in LPS-induced sepsis. Fundamental & clinical pharmacology 20101201
Activation of mitogen-activated protein kinases cellular signal transduction pathway in mammalian cells induced by silicon carbide nanowires. Biomaterials 20101101
Effect of flunixin meglumine and carprofen on pregnancy rates in dairy cattle. Journal of dairy science 20101101
High-throughput microplate assay for the determination of drug partition coefficients. Nature protocols 20101101
Efficacy of single-dose intravenous phenylbutazone and flunixin meglumine before, during and after exercise in an experimental reversible model of foot lameness in horses. Equine veterinary journal. Supplement 20101101
Effects of flunixin on cardiorespiratory, plasma lactate and stride length responses to intense treadmill exercise in Standardbred trotters. Equine veterinary journal. Supplement 20101101
[Simultaneous analysis of 4 non-steroidal anti-inflammatory drug residues in mutton muscle using high performance liquid chromatography assisted by ultrasonic-microwave extraction]. Se pu = Chinese journal of chromatography 20101101
A comparative study on the adverse effects of flunixin, ketoprofen and phenylbutazone in miniature donkeys: haematological, biochemical and pathological findings. New Zealand veterinary journal 20101001
Effects of enrofloxacin, flunixin meglumine and dexamethasone on disseminated intravascular coagulation, cytokine levels and adenosine deaminase activity in endotoxaemia in rats. Acta veterinaria Hungarica 20100901
Effects of ring castration with local anesthesia and analgesia in Holstein calves at 3 months of age on welfare indicators. Journal of animal science 20100801
Effect of analgesia during hoof trimming on gait, weight distribution, and activity of dairy cattle. Journal of dairy science 20100701
The effects of perioperative analgesia on litter size in Crl:CD1(ICR) mice undergoing embryo transfer. Journal of the American Association for Laboratory Animal Science : JAALAS 20100701
Use of a five-day progesterone-based timed AI protocol to determine if flunixin meglumine improves pregnancy per timed AI in dairy heifers. Theriogenology 20100601
Clinical efficacy of diclofenac sodium and flunixin meglumine as adjuncts to antibacterial treatment of respiratory disease of calves. Australian veterinary journal 20100601
Pharmacokinetics of flunixin in chickens after oral and intravenous administration. Journal of veterinary pharmacology and therapeutics 20100601
Bioequivalence of 250 mg lysine clonixinate tablets after a single oral dose in a healthy female Mexican population under fasting conditions. International journal of clinical pharmacology and therapeutics 20100501
Effects of drugs used in endotoxic shock on oxidative stress and organ damage markers. Free radical research 20100401
Effects of flunixin meglumine on pregnancy establishment in beef cattle. Journal of animal science 20100301
Randomized clinical trial of long-acting oxytetracycline, foot trimming, and flunixine meglumine on time to recovery in sheep with footrot. Journal of veterinary internal medicine 20100101
Evaluation of the influence of meloxicam and flunixin meglumine on the apoptosis of peripheral blood CD4+ and CD8+ T cells in calves. Polish journal of veterinary sciences 20100101
Exploring non-invasive methods to assess pain in sheep. Physiology & behavior 20091207
Effect of oxytocin and flunixin meglumine on uterine response to insemination in mares. Theriogenology 20091201
Anti-inflammatory effects of intravenously administered lidocaine hydrochloride on ischemia-injured jejunum in horses. American journal of veterinary research 20091001
Effect of day of transfer and treatment administration on the recipient on pregnancy rates after equine embryo transfer. Veterinary research communications 20090901
Treatment of pregnancy toxaemia in sheep with flunixin meglumine. The Veterinary record 20090829
Analgesic efficacy of lysine clonixinate, paracetamol and dipyrone in lower third molar extraction: a randomized controlled trial. Medicina oral, patologia oral y cirugia bucal 20090801
Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum. American journal of veterinary research 20090801
Effects of flunixin meglumine on pyrexia and bioenergetic variables in postparturient dairy cows. Journal of dairy science 20090501
A physiologically based pharmacokinetic model linking plasma protein binding interactions with drug disposition. Research in veterinary science 20090401
In-house reference materials: 5-hydroxyflunixin and meloxicam in cow milk-preparation and evaluation. Analytica chimica acta 20090401
The behavioral assessment and alleviation of pain associated with castration in beef calves treated with flunixin meglumine and caudal lidocaine epidural anesthesia with epinephrine. The Canadian veterinary journal = La revue veterinaire canadienne 20090401
Effects of nonselective and selective cyclooxygenase inhibitors on small intestinal motility in the horse. Research in veterinary science 20090201
Effects of flunixin meglumine on recovery of colonic mucosa from ischemia in horses. American journal of veterinary research 20090201
Optimized surgical techniques and postoperative care improve survival rates and permit accurate telemetric recording in exercising mice. BMC veterinary research 20090101
A comparison of florfenicol-flunixin meglumine versus tulathromycin for the treatment of undifferentiated fever in fall-placed feedlot calves. Veterinary therapeutics : research in applied veterinary medicine 20090101
Efficacy of a florfenicol-flunixin meglumine combination product versus tulathromycin or ceftiofur crystalline free acid for the treatment of undifferentiated fever in feedlot calves. Veterinary therapeutics : research in applied veterinary medicine 20090101
Incomplete placentation after twin reduction in a mare. The Veterinary record 20081201
Embryo transfer induces a subclinical endometritis in recipient mares which can be prevented by treatment with non-steroid anti-inflammatory drugs. Theriogenology 20081015
Drug contamination of the equine racetrack environment: a preliminary examination. Journal of veterinary pharmacology and therapeutics 20081001
Pharmacokinetics of enrofloxacin and flunixin meglumine and interactions between both drugs after intravenous co-administration in healthy and endotoxaemic rabbits. Veterinary journal (London, England : 1997) 20080901
Attenuation of ischaemic injury in the equine jejunum by administration of systemic lidocaine. Equine veterinary journal 20080601
Effects of nonsteroidal anti-inflammatory drugs on long-term pain in calves castrated by use of an external clamping technique following epidural anesthesia. American journal of veterinary research 20080601
Lysine clonixinate versus dipyrone (metamizole) for the acute treatment of severe migraine attacks: a single-blind, randomized study. Arquivos de neuro-psiquiatria 20080601
Flunixin horse pill use in human associated with peptic ulcer disease. The Annals of pharmacotherapy 20080301
Extralabel use of nonsteroidal anti-inflammatory drugs in cattle. Journal of the American Veterinary Medical Association 20080301
Escherichia coli mastitis in cattle being treated for Staphylococcus aureus intramammary infection. The Veterinary record 20080202
Effectiveness of administration of phenylbutazone alone or concurrent administration of phenylbutazone and flunixin meglumine to alleviate lameness in horses. American journal of veterinary research 20080201
Effect of preoperative administration of erythromycin or flunixin meglumine on postoperative abomasal emptying rate in dairy cows undergoing surgical correction of left displacement of the abomasum. Journal of the American Veterinary Medical Association 20080201
Pharmacokinetics of flunixin in mature heifers following multiple intravenous administration. Polish journal of veterinary sciences 20080101
Outcome of medical and surgical treatment of cecal impaction in horses: 114 cases (1994-2004). Journal of the American Veterinary Medical Association 20071101
Effect of flunixin meglumine on cytokine levels in experimental endotoxemia in mice. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20070901
Treatment of acute puerperal metritis with flunixin meglumine in addition to antibiotic treatment. Journal of dairy science 20070801
Suspected panosteitis in a camel. Journal of the American Veterinary Medical Association 20070801
FDA issues reminder on correct use of flunixin meglumine. Journal of the American Veterinary Medical Association 20070701
Evaluation of the renal effects of flunixin meglumine, ketoprofen and meloxicam in budgerigars (Melopsittacus undulatus). The Veterinary record 20070616
Effects of flunixin meglumine and transportation on establishment of pregnancy in beef cows. Journal of animal science 20070601
Effects of the cyclooxygenase inhibitor meloxicam on recovery of ischemia-injured equine jejunum. American journal of veterinary research 20070601
Pharmacokinetic interactions of flunixin meglumine and enrofloxacin in ICR mice. Experimental animals 20070401
Effect of the administration of flunixin meglumine on pregnancy rates in Holstein heifers. The Veterinary record 20070324
Rapid method for the determination of non-steroidal anti-inflammatory drugs in animal tissue by liquid chromatography-mass spectrometry with ion-trap detector. Analytica chimica acta 20070314
Evaluation of adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs. American journal of veterinary research 20070301
In vitro effects of reactive oxygen metabolites, with and without flunixin meglumine, on equine colonic mucosa. American journal of veterinary research 20070301
The effect of a topical anaesthetic formulation, systemic flunixin and carprofen, singly or in combination, on cortisol and behavioural responses of Merino lambs to mulesing. Australian veterinary journal 20070301
Outbreak of neurologic disease caused by equine herpesvirus-1 at a university equestrian center. Journal of veterinary internal medicine 20070101
Assessment of post-laparotomy pain in laboratory mice by telemetric recording of heart rate and heart rate variability. BMC veterinary research 20070101
Effects of cyclooxygenase inhibition on the gastrointestinal tract. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20061101
Pharmacokinetics of flunixin meglumine in swine after intravenous dosing. Journal of veterinary pharmacology and therapeutics 20061001
Effects of flunixin meglumine on selected clinicopathologic variables, and serum testosterone concentration in stallions after endotoxin administration. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20060901
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Questions dosage used in equine study. American journal of veterinary research 20060501
Actinobacillus peritonitis in a Warmblood gelding. The Veterinary clinics of North America. Equine practice 20060401
Postpartum hemoperitoneum and septic peritonitis in a Thoroughbred mare. The Veterinary clinics of North America. Equine practice 20060401
Acute diarrhea in the adult horse: case example and review. The Veterinary clinics of North America. Equine practice 20060401
Malabsorptive maldigestive disorder with concurrent Salmonella in a 3-year-old quarter horse. The Veterinary clinics of North America. Equine practice 20060401
Equine herpes myeloencephalopathy in a 12-year-old American quarter horse. The Veterinary clinics of North America. Equine practice 20060401
Efficacy of ceftiofur and flunixin in the early treatment of bronchopneumonia in weaners. The Veterinary record 20060304
Effects of phenylbutazone alone or in combination with flunixin meglumine on blood protein concentrations in horses. American journal of veterinary research 20060301
Pharmacokinetics of flunixin after intravenous administration in healthy and endotoxaemic rabbits. Veterinary research communications 20060101
COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis. Pharmacological research 20051001
Effect of a CIDR insert and flunixin meglumine, administered at the time of embryo transfer, on pregnancy rate and resynchronization of estrus in beef cattle. Theriogenology 20050901
Technical Note: Improved technique for fitting pigs with steered ileocecal valve cannulas. Journal of animal science 20050701
Pharmacokinetic interactions of flunixin meglumine and enrofloxacin in dogs. American journal of veterinary research 20050701
Interaction of clonixin with EPC liposomes used as membrane models. Journal of pharmaceutical sciences 20050601
Effect of anti-inflammatory drugs on splenocyte membrane fluidity. Analytical biochemistry 20050401
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics 20050401
Investigation of the effect of black walnut extract on in vitro ion transport and structure of equine colonic mucosa. American journal of veterinary research 20050301
Effects of non-steroidal anti-inflammatory drugs on pain-related behaviour in a model of articular pain in the domestic fowl. Research in veterinary science 20050201
Use of force plate analysis to compare the analgesic effects of intravenous administration of phenylbutazone and flunixin meglumine in horses with navicular syndrome. American journal of veterinary research 20050201
Evaluating postoperative analgesics in mice using telemetry. Comparative medicine 20050201
Effects of cyclooxygenase inhibitors flunixin and deracoxib on permeability of ischaemic-injured equine jejunum. Equine veterinary journal 20050101
Lysine clonixinate vs naproxen sodium for the acute treatment of migraine: a double-blind, randomized, crossover study. MedGenMed : Medscape general medicine 20050101
[Slaughter emergency]. Tijdschrift voor diergeneeskunde 20041101
Field evaluation of flunixin meglumine in the supportive treatment of caprine mastitis. Journal of veterinary pharmacology and therapeutics 20041001
Effects of ischemia and the cyclooxygenase inhibitor flunixin on in vitro passage of lipopolysaccharide across equine jejunum. American journal of veterinary research 20041001
Disposition of flunixin meglumine injectable preparation administered orally to healthy horses. Journal of veterinary pharmacology and therapeutics 20040601
Effects of flunixin meglumine or etodolac treatment on mucosal recovery of equine jejunum after ischemia. American journal of veterinary research 20040601
Effect of morphine and flunixin meglumine on isoflurane minimum alveolar concentration in goats. Veterinary anaesthesia and analgesia 20040401
Pharmacokinetics of flunixin in the cat: enterohepatic circulation and active transport mechanism in the liver. Journal of veterinary pharmacology and therapeutics 20040401
Quantification and confirmation of flunixin in equine plasma by liquid chromatography-quadrupole time-of-flight tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040305
Effects of two anti-inflammatory drugs on physiologic variables and milk production in cows with endotoxin-induced mastitis. American journal of veterinary research 20040101
Clinical efficacy of meloxicam (Metacam) and flunixin (Finadyne) as adjuncts to antibacterial treatment of respiratory disease in fattening cattle. Berliner und Munchener tierarztliche Wochenschrift 20040101
Determination of flunixin in edible bovine tissues using liquid chromatography coupled with tandem mass spectrometry. Journal of agricultural and food chemistry 20031217
Role of prostaglandins in the development of hyperthermia in heat-stressed, lactating Holstein cows. Journal of veterinary pharmacology and therapeutics 20031201
Evaluation of flunixin meglumine as an adjunct treatment for diarrhea in dairy calves. Journal of the American Veterinary Medical Association 20031101
Investigation on the efficacy of meloxicam in sows with mastitis-metritis-agalactia syndrome. Journal of veterinary pharmacology and therapeutics 20031001
Residue depletion study and withdrawal period for flunixin-N-methyl glucamine in bovine milk following intravenous administration. Journal of agricultural and food chemistry 20030730
Determination and confirmation of 5-hydroxyflunixin in raw bovine milk using liquid chromatography tandem mass spectrometry. Journal of agricultural and food chemistry 20030618
Clinical efficacy of flunixin, carprofen and ketoprofen as adjuncts to the antibacterial treatment of bovine respiratory disease. The Veterinary record 20030329
Atropine reverses the antinociception of nonsteroidal anti-inflammatory drugs in the tail-flick test of mice. Pharmacology, biochemistry, and behavior 20030201
Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa B. American journal of veterinary research 20030201
Comparative pharmacokinetics of three non-steroidal anti-inflammatory drugs in five bird species. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030101
Evaluation of postoperative analgesia in a rat model of incisional pain. Contemporary topics in laboratory animal science 20030101
A comparative study of the effects of meloxicam and flunixin meglumine (NSAIDs) as adjunctive therapy on interferon and tumor necrosis factor production in calves suffering from enzootic bronchopneumonia. Polish journal of veterinary sciences 20030101
Pharmacokinetics and pharmacodynamic effects of flunixin after intravenous, intramuscular and oral administration to dairy goats. Acta veterinaria Scandinavica 20030101
Flunixin residues in milk after intravenous treatment of dairy cattle with (14)C-flunixin. Journal of agricultural and food chemistry 20021204
Kinetics of venom and antivenom serum and clinical parameters and treatment efficacy in Bothrops alternatus envenomed dogs. Veterinary and human toxicology 20021201
Disposition of sodium salicylate, flunixin and meloxicam after intravenous administration in broiler chickens. Journal of veterinary pharmacology and therapeutics 20021201
Efficacy and pharmacokinetics of enrofloxacin and flunixin meglumine for treatment of cows with experimentally induced Escherichia coli mastitis. Journal of veterinary pharmacology and therapeutics 20020801
The effects of cyclo-oxygenase inhibitors on bile-injured and normal equine colon. Equine veterinary journal 20020701
In vitro investigation of the interaction between nitric oxide and cyclo-oxygenase activity in equine ventral colon smooth muscle. Equine veterinary journal 20020701
Non-surgical management of rectal tears in two mares. Australian veterinary journal 20020301
Extraction and LC determination of lysine clonixinate salt in water/oil microemulsions. Journal of pharmaceutical and biomedical analysis 20020201
15-Ketodihydro-PGF(2 alpha), progesterone and uterine involution in primiparous cows with induced retained placenta and post-partal endometritis treated with oxytetracycline and flunixin. Reproduction in domestic animals = Zuchthygiene 20020201
Microemulsion formulation of clonixic acid: solubility enhancement and pain reduction. The Journal of pharmacy and pharmacology 20020101
Effect of flunixin meglumine on selected physiologic and performance parameters of athletically conditioned thoroughbred horses subjected to an incremental exercise stress test. Veterinary therapeutics : research in applied veterinary medicine 20020101
Investigation of factors affecting pregnancy rate after embryo transfer in the dromedary camel. Reproduction, fertility, and development 20020101
In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats. American journal of veterinary research 20011101
Effect of lysine clonixinate on the pharmacokinetics and anticoagulant activity of phenprocoumon. Arzneimittel-Forschung 20011101
Pharmacokinetics of flunixin meglumine in llamas following a single intravenous dose. Journal of veterinary pharmacology and therapeutics 20011001
Flunixin meglumine accelerates uterine involution and shortens the calving-to-first-oestrus interval in cows with puerperal metritis. Journal of veterinary pharmacology and therapeutics 20011001
Clinical and bacteriological aspects on the use of oxytetracycline and flunixin in primiparous cows with induced retained placenta and post-partal endometritis. Reproduction in domestic animals = Zuchthygiene 20011001
Possible active transport mechanism in pharmacokinetics of flunixin-meglumin in rabbits. The Journal of veterinary medical science 20010801
Pharmacodynamics of flunixin and ketoprofen in mallard ducks (Anas platyrhynchos). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20010601
Effects of steroidal and non-steroidal antiphlogistic drugs on eicosanoid synthesis in irritated skin: studies with the isolated perfused bovine udder. The Journal of pharmacy and pharmacology 20010501
Role of prostaglandins in intrauterine migration of the equine conceptus. Reproduction (Cambridge, England) 20010501
In vivo and in vitro effects of lysine clonixinate on nitric oxide synthase in LPS-treated and untreated rat lung preparations. Nitric oxide : biology and chemistry 20010401
Effect of finadyne on oestradiol-induced ovarian oxytocin and uterine PGF2alpha secretory systems on day 15 after oestrus in ovarian autotransplanted ewes. Reproduction (Cambridge, England) 20010301
Oral lysine clonixinate in the acute treatment of migraine: a double-blind placebo-controlled study. Arquivos de neuro-psiquiatria 20010301
Intermittent hypoglycemia in a horse with anaplastic carcinoma of the kidney. Journal of the American Veterinary Medical Association 20010115
Abdominal radiography in monitoring the resolution of sand accumulations from the large colon of horses treated medically. Equine veterinary journal 20010101
Effects of anti-inflammatory drugs on lipopolysaccharide-challenged and -unchallenged equine synovial explants. American journal of veterinary research 20010101
Determination of flunixin residues in bovine muscle tissue by liquid chromatography with UV detection. Journal of AOAC International 20010101
[Effects of lysine clonixinate on platelet function. Comparison with other non-steroidal anti-inflammatory agents]. Medicina 20010101
Antispasmodic/analgesic associations in primary dysmenorrhea double-blind crossover placebo-controlled clinical trial. International journal of clinical pharmacology research 20010101
[Effect of nonsteroidal antiinflammatory drugs on colonic lipoxygenase and cyclooxygenase activities from patients with colonic neoplasia]. Medicina 20010101
Effects of butorphanol, flunixin, levorphanol, morphine, and xylazine in ponies. American journal of veterinary research 19840201
Clonixin: a clinical evaluation of a new oral analgesic. The Journal of clinical pharmacology and new drugs 19710101
Properties