(2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid
Title | Journal |
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Endothelin-1 receptor antagonists in fetal development and pulmonary arterial hypertension. | Reproductive toxicology (Elmsford, N.Y.) 20150815 |
Ambrisentan for the treatment of adults with pulmonary arterial hypertension: a review. | Current medical research and opinion 20150101 |
AMBITION: An important piece in the therapeutic puzzle of pulmonary arterial hypertension. | Global cardiology science & practice 20150101 |
Lack of a clinically significant interaction of grapefruit juice with ambrisentan and bosentan in healthy adults. | International journal of clinical pharmacology and therapeutics 20141101 |
Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1. | European journal of clinical pharmacology 20131001 |
Clinical pharmacokinetics and drug-drug interactions of endothelin receptor antagonists in pulmonary arterial hypertension. | Journal of clinical pharmacology 20121201 |
Frequency of edema in patients with pulmonary arterial hypertension receiving ambrisentan. | The American journal of cardiology 20121101 |
Safety and efficacy evaluation of ambrisentan in pulmonary hypertension. | Expert opinion on drug safety 20121101 |
Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways. | Life sciences 20121015 |
Defining the affinity and receptor sub-type selectivity of four classes of endothelin antagonists in clinically relevant human cardiovascular tissues. | Life sciences 20121015 |
Endothelin receptor antagonists for the treatment of pulmonary artery hypertension. | Life sciences 20121015 |
The combination of theophylline and endothelin receptor antagonism improves exercise performance of rats under simulated high altitude. | Journal of applied physiology (Bethesda, Md. : 1985) 20121015 |
LC-ESI-MS/MS method for quantification of ambrisentan in plasma and application to rat pharmacokinetic study. | Biomedical chromatography : BMC 20121001 |
Long-term hepatic safety of ambrisentan in patients with pulmonary arterial hypertension. | Journal of the American College of Cardiology 20120703 |
Long-term safety and efficacy of ambrisentan in Japanese adults with pulmonary arterial hypertension. | Current medical research and opinion 20120601 |
Treatment of pulmonary arterial hypertension in connective tissue disease. | Drugs 20120528 |
Risk evaluation and mitigation strategies: assessment of a medical center's policies and procedures. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120515 |
Chronic endothelin A receptor blockade attenuates contribution of sympathetic nervous system to salt hypertension development in adult but not in young Dahl rats. | Acta physiologica (Oxford, England) 20120501 |
Ambrisentan for pulmonary arterial hypertension: long term effects on clinical status, exercise capacity and haemodynamics. | International journal of cardiology 20120419 |
Endothelin-1 promotes cytoplasmic accumulation of RIP140 through a ET(A)-PLCβ-PKCε pathway. | Molecular and cellular endocrinology 20120404 |
ARIES-3: ambrisentan therapy in a diverse population of patients with pulmonary hypertension. | Cardiovascular therapeutics 20120401 |
eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype. | Journal of the American Society of Nephrology : JASN 20120401 |
Rapid determination of ambrisentan enantiomers by enantioselective liquid chromatography using cellulose-based chiral stationary phase in reverse phase mode. | Journal of separation science 20120401 |
Effect of cyclosporine and rifampin on the pharmacokinetics of macitentan, a tissue-targeting dual endothelin receptor antagonist. | The AAPS journal 20120301 |
Ambrisentan and tadalafil synergistically relax endothelin-induced contraction of rat pulmonary arteries. | Hypertension (Dallas, Tex. : 1979) 20120301 |
Synthesis of (+)-ambrisentan via chiral ketone-catalyzed asymmetric epoxidation. | The Journal of organic chemistry 20120106 |
Race and sex differences in response to endothelin receptor antagonists for pulmonary arterial hypertension. | Chest 20120101 |
Inhaled treprostinil: a therapeutic review. | Drug design, development and therapy 20120101 |
Pulmonary arterial hypertension: advances in pathophysiology and management. | Indian journal of pharmacology 20120101 |
A novel expression of exercise induced pulmonary hypertension in human immunodeficiency virus patients: a pilot study. | The open cardiovascular medicine journal 20120101 |
Treatment patterns and healthcare system burden of managed care patients with suspected pulmonary arterial hypertension in the United States. | Journal of medical economics 20120101 |
Smooth muscle myosin inhibition: a novel therapeutic approach for pulmonary hypertension. | PloS one 20120101 |
Slow receptor dissociation kinetics differentiate macitentan from other endothelin receptor antagonists in pulmonary arterial smooth muscle cells. | PloS one 20120101 |
Pulmonary arterial hypertension: an update. | Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20111201 |
[Treatment of pulmonary fibrosis. New substances and new interventions]. | Der Internist 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Adult congenital heart disease and pulmonary arterial hypertension: the Texas Adult Congenital Heart Program experience. | Postgraduate medicine 20111101 |
Macitentan: entry-into-humans study with a new endothelin receptor antagonist. | European journal of clinical pharmacology 20111001 |
Endothelin receptor antagonists -- their role in pulmonary medicine. | Revue des maladies respiratoires 20111001 |
Ambrisentan for sarcoidosis associated pulmonary hypertension. | Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20111001 |
Efficacy, safety, and pharmacokinetics of ambrisentan in Japanese adults with pulmonary arterial hypertension. | Current medical research and opinion 20110901 |
Ambrisentan improves exercise capacity and symptoms in patients with portopulmonary hypertension. | Zeitschrift fur Gastroenterologie 20110901 |
Bosentan and oral anticoagulants in HIV patients: what we can learn of cases reported so far. | Hematology reports 20110831 |
Ambrisentan. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20110801 |
Long-term pulmonary hemodynamic effects of ambrisentan in pulmonary arterial hypertension. | The American journal of cardiology 20110715 |
Endothelin receptor antagonists for the treatment of pulmonary arterial hypertension. | Expert opinion on pharmacotherapy 20110701 |
Synthesis and in vitro evaluation of ambrisentan analogues as potential endothelin receptor antagonists. | Bioorganic & medicinal chemistry letters 20110701 |
[Treatment of idiopathic pulmonary arterial hypertension]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110701 |
Differential modulation of the expression of important drug metabolising enzymes and transporters by endothelin-1 receptor antagonists ambrisentan and bosentan in vitro. | European journal of pharmacology 20110625 |
New perspectives for the treatment of pulmonary hypertension. | British journal of pharmacology 20110501 |
Novel therapeutic approaches for pulmonary fibrosis. | British journal of pharmacology 20110501 |
Ambrisentan for pulmonary arterial hypertension due to congenital heart disease. | The American journal of cardiology 20110501 |
With REMS, what goes up can come down. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110501 |
Treprostinil increases the number and angiogenic potential of endothelial progenitor cells in children with pulmonary hypertension. | Angiogenesis 20110301 |
Survival after the initiation of combination therapy in patients with pulmonary arterial hypertension: an Australian collaborative report. | Internal medicine journal 20110301 |
Pharmacokinetic evaluation of ambrisentan. | Expert opinion on drug metabolism & toxicology 20110301 |
Hepatotoxicity by bosentan in a patient with portopulmonary hypertension: a case-report and review of the literature. | Journal of gastrointestinal and liver diseases : JGLD 20110301 |
[Changes long term prognosis of 17 patients with pulmonary artery hypertension]. | Revista medica de Chile 20110301 |
Endothelin receptor antagonists as disease modifiers in systemic sclerosis. | Inflammation & allergy drug targets 20110201 |
Effects of multiple doses of ambrisentan on the pharmacokinetics of a single dose of digoxin in healthy volunteers. | Journal of clinical pharmacology 20110101 |
Safety and efficacy of ambrisentan for the treatment of portopulmonary hypertension. | Chest 20110101 |
Identification of clinically used drugs that activate pregnane X receptors. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
Availability of and access to orphan drugs: an international comparison of pharmaceutical treatments for pulmonary arterial hypertension, Fabry disease, hereditary angioedema and chronic myeloid leukaemia. | PharmacoEconomics 20110101 |
Effect of transition from sitaxsentan to ambrisentan in pulmonary arterial hypertension. | Vascular health and risk management 20110101 |
Pulmonary vascular complications of chronic liver disease: Pathophysiology, imaging, and treatment. | Annals of thoracic medicine 20110101 |
Short term effects of exercise training on exercise capacity and quality of life in patients with pulmonary arterial hypertension: protocol for a randomised controlled trial. | BMC pulmonary medicine 20110101 |
[Pulmonary arterial hypertension: changing approaches to management]. | Kardiologiia 20110101 |
Recent trends in pulmonary arterial hypertension. | Lung India : official organ of Indian Chest Society 20110101 |
Therapeutic strategies in pulmonary hypertension. | Frontiers in pharmacology 20110101 |
Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice. | Arthritis research & therapy 20110101 |
Does market exclusivity hinder the development of Follow-on Orphan Medicinal Products in Europe? | Orphanet journal of rare diseases 20110101 |
Diagnosis and management of pulmonary arterial hypertension. | Pulmonary medicine 20110101 |
Anaesthesia Management of Caesarean Section in Two Patients with Eisenmenger's Syndrome. | Anesthesiology research and practice 20110101 |
Diagnostic and therapeutic algorithm for pulmonary arterial hypertension. | Pulmonary circulation 20110101 |
Overview of current therapeutic approaches for pulmonary hypertension. | Pulmonary circulation 20110101 |
Vascular involvement in systemic sclerosis (scleroderma). | Journal of inflammation research 20110101 |
Assessment of daily life physical activities in pulmonary arterial hypertension. | PloS one 20110101 |
Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis. | International journal of rheumatology 20110101 |
Long-term effects of intravenous iloprost in patients with idiopathic pulmonary arterial hypertension deteriorating on non-parenteral therapy. | BMC pulmonary medicine 20110101 |
Effect and safety of mycophenolate mofetil in idiopathic pulmonary fibrosis. | Pulmonary medicine 20110101 |
Surgical treatment of pulmonary hypertension: Lung transplantation. | Pulmonary circulation 20110101 |
Early intervention in pulmonary arterial hypertension associated with systemic sclerosis: an essential component of disease management. | European respiratory review : an official journal of the European Respiratory Society 20101201 |
The Adult Patient with Eisenmenger Syndrome: A Medical Update after Dana Point Part II: Medical Treatment - Study Results. | Current cardiology reviews 20101101 |
Potential for pharmacokinetic interactions between ambrisentan and cyclosporine. | Clinical pharmacology and therapeutics 20101001 |
Pulmonary arterial hypertension: from the kingdom of the near-dead to multiple clinical trial meta-analyses. | European heart journal 20100901 |
Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes. | Canadian journal of physiology and pharmacology 20100601 |
Combined vasomodulatory therapy for severe pulmonary hypertension in chronic hypersensitivity pneumonitis. | Medical science monitor : international medical journal of experimental and clinical research 20100501 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20100501 |
[Pulmonary circulation: contributions of the year 2009]. | Archivos de bronconeumologia 20100301 |
Long-term outcomes with ambrisentan monotherapy in pulmonary arterial hypertension. | Journal of cardiac failure 20100201 |
[Endothelin receptor antagonists in the new European guidelines on pulmonary hypertension]. | Revue des maladies respiratoires 20100201 |
Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis. | Respiratory research 20100101 |
Pulmonary arterial hypertension in connective tissue diseases. | Cardiology in review 20100101 |
Hemodynamics in pulmonary arterial hypertension (PAH): do they explain long-term clinical outcomes with PAH-specific therapy? | BMC cardiovascular disorders 20100101 |
Oral Therapies for the treatment of pulmonary arterial hypertension: a population-based cost-minimization analysis. | Applied health economics and health policy 20100101 |
Portopulmonary hypertension. | Annals of thoracic medicine 20100101 |
Effect of steady-state ambrisentan on the pharmacokinetics of a single dose of the oral contraceptive norethindrone (norethisterone) 1 mg/ethinylestradiol 35 microg in healthy subjects: an open-label, single-sequence, single-centre study. | Clinical drug investigation 20100101 |
Pharmacotherapeutic management of pulmonary arterial hypertension. | Cardiology in review 20100101 |
The emergence of oral tadalafil as a once-daily treatment for pulmonary arterial hypertension. | Vascular health and risk management 20100101 |
Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension. | Drug design, development and therapy 20100101 |
Adult patients with pulmonary arterial hypertension due to congenital heart disease: a review on advanced medical treatment with bosentan. | Therapeutics and clinical risk management 20100101 |
Effects of rifampicin (rifampin) on the pharmacokinetics and safety of ambrisentan in healthy subjects: a single-sequence, open-label study. | Clinical drug investigation 20100101 |
Inhaled treprostinil and pulmonary arterial hypertension. | Vascular health and risk management 20100101 |
Phosphodiesterase-5 inhibitors in management of pulmonary hypertension: safety, tolerability, and efficacy. | Drug, healthcare and patient safety 20100101 |
No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers. | Journal of pharmaceutical sciences 20091201 |
Endothelin receptor antagonists for pulmonary hypertension in adult patients with sickle cell disease. | British journal of haematology 20091201 |
[Endothelin receptor antagonists - their role in pulmonary medicine]. | Revue des maladies respiratoires 20091201 |
Long-term ambrisentan therapy for the treatment of pulmonary arterial hypertension. | Journal of the American College of Cardiology 20091117 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20091101 |
Can we improve outcome of congenital diaphragmatic hernia? | Pediatric surgery international 20090901 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090901 |
Ambrisentan, an endothelin receptor type A-selective endothelin receptor antagonist, for the treatment of pulmonary arterial hypertension. | Expert opinion on pharmacotherapy 20090801 |
Use of inhaled iloprost in an infant with bronchopulmonary dysplasia and pulmonary artery hypertension. | Korean circulation journal 20090801 |
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan. | Journal of clinical pharmacology 20090601 |
Pulmonary arterial hypertension: the most devastating vascular complication of systemic sclerosis. | Rheumatology (Oxford, England) 20090601 |
Small-molecule endothelin receptor antagonists: a review of patenting activity across therapeutic areas. | IDrugs : the investigational drugs journal 20090601 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090601 |
The pharmacokinetics and pharmacodynamics of warfarin in combination with ambrisentan in healthy volunteers. | British journal of clinical pharmacology 20090501 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090401 |
Ambrisentan: new drug. Too risky in mildly symptomatic pulmonary hypertension. | Prescrire international 20090401 |
A meta-analysis of randomized controlled trials in pulmonary arterial hypertension. | European heart journal 20090201 |
Ambrisentan therapy in patients with pulmonary arterial hypertension who discontinued bosentan or sitaxsentan due to liver function test abnormalities. | Chest 20090101 |
[Pulmonary arterial hypertension: a voyage around the year 2008]. | Archivos de bronconeumologia 20090101 |
Pulmonary arterial hypertension in children: a medical update. | Indian journal of pediatrics 20090101 |
Review of inhaled iloprost for the control of pulmonary artery hypertension in children. | Vascular health and risk management 20090101 |
New concepts in the invasive and non invasive evaluation of remodelling of the right ventricle and pulmonary vasculature in pulmonary arterial hypertension. | The open respiratory medicine journal 20090101 |
Endothelin-1 inhibition by ambrisentan as a potential treatment adjunct after debulking surgery in epithelial ovarian cancer. | Oncology research 20090101 |
Treatment of pediatric pulmonary hypertension. | Vascular health and risk management 20090101 |
Oral therapies for the treatment of pulmonary arterial hypertension: a population-based cost-minimization analysis. | Applied health economics and health policy 20090101 |
Bosentan in the treatment of pulmonary arterial hypertension with the focus on the mildly symptomatic patient. | Vascular health and risk management 20090101 |
Cost-utility of treatments for pulmonary arterial hypertension: a Markov state-transition decision analysis model. | Clinical drug investigation 20090101 |
Safety and tolerability of bosentan in the management of pulmonary arterial hypertension. | Drug design, development and therapy 20090101 |
Therapeutic methods used in patients with Eisenmenger syndrome. | Cardiology journal 20090101 |
Integrated care and optimal management of pulmonary arterial hypertension. | Journal of multidisciplinary healthcare 20090101 |
Pharmacokinetics and safety of ambrisentan in combination with sildenafil in healthy volunteers. | Journal of clinical pharmacology 20081201 |
Ambrisentan and its role in the management of pulmonary arterial hypertension. | Drugs of today (Barcelona, Spain : 1998) 20081201 |
Role of ambrisentan in the management of pulmonary hypertension. | The Annals of pharmacotherapy 20081101 |
[Specific drugs for the treatment of pulmonary arterial hypertension - current status]. | Deutsche medizinische Wochenschrift (1946) 20081001 |
Optimizing endothelin receptor antagonist use in the management of pulmonary arterial hypertension. | Vascular health and risk management 20081001 |
Pulmonary arterial hypertension: on the way to a manageable disease. | Current opinion in investigational drugs (London, England : 2000) 20080901 |
Inhibition of endothelin receptors in the treatment of pulmonary arterial hypertension: does selectivity matter? | European heart journal 20080801 |
[Current treatment of systemic sclerosis. Part II. Vascular and antifibrotic treatment]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20080801 |
The management of pulmonary hypertension in children. | Archives of disease in childhood 20080701 |
Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2. | Circulation 20080610 |
The status of pulmonary arterial hypertension in 2008. | Circulation 20080610 |
[Systemic sclerosis]. | Medizinische Monatsschrift fur Pharmazeuten 20080501 |
Ambrisentan for the management of pulmonary arterial hypertension. | Clinical therapeutics 20080501 |
[Treatment of pulmonary arterial hypertension by endothelin receptor antagonists in 2008]. | La Revue de medecine interne 20080401 |
The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house? | British journal of pharmacology 20080301 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20080301 |
Endothelin receptor antagonists in pulmonary arterial hypertension. | The European respiratory journal 20080201 |
Acute right ventricular failure in the setting of acute pulmonary embolism or chronic pulmonary hypertension: a detailed review of the pathophysiology, diagnosis, and management. | Current cardiology reviews 20080201 |
Endothelin receptor antagonists for pulmonary arterial hypertension: rationale and place in therapy. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101 |
Effects of selective and unselective endothelin-receptor antagonists on prostacyclin synthase gene expression in experimental pulmonary hypertension. | Scandinavian journal of clinical and laboratory investigation 20080101 |
Endothelin receptor antagonism: role in the treatment of pulmonary arterial hypertension related to scleroderma. | Drugs 20080101 |
Ambrisentan. | Drugs 20080101 |
Pulmonary hypertension: past, present and future. | Annals of thoracic medicine 20080101 |
Ambrisentan for the treatment of pulmonary arterial hypertension. | Drug design, development and therapy 20080101 |
Review of bosentan in the management of pulmonary arterial hypertension. | Vascular health and risk management 20071201 |
Ambrisentan (Letairis) for pulmonary arterial hypertension. | The Medical letter on drugs and therapeutics 20071022 |
Systematic review of randomised, double-blind clinical trials of oral agents conducted in patients with pulmonary arterial hypertension. | International journal of clinical practice 20071001 |
Expert opinion on available options treating pulmonary arterial hypertension. | Expert opinion on pharmacotherapy 20071001 |
Ambrisentan. | Nature reviews. Drug discovery 20070901 |
Therapeutic challenges for systemic sclerosis: facts and future targets. | Annals of the New York Academy of Sciences 20070901 |
New drug approved for pulmonary arterial hypertension. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070801 |
EndothelinA receptor antagonist BSF-208075 causes immune modulation and neuroprotection after stroke in gerbils. | Brain research 20070709 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20070401 |
Pathophysiological role of platelets in acute experimental pancreatitis: influence of endothelin A receptor blockade. | Cell and tissue research 20070301 |
Endothelin receptor antagonists in the treatment of pulmonary arterial hypertension. | Clinics in chest medicine 20070301 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20070301 |
A review of pulmonary arterial hypertension: role of ambrisentan. | Vascular health and risk management 20070201 |
Therapeutic targets in systemic sclerosis. | Arthritis research & therapy 20070101 |
New drugs: ambrisentan, temsirolimus, and eculizumab. | Journal of the American Pharmacists Association : JAPhA 20070101 |
[Pulmonary hypertension and right ventricular failure. Part XI. Endothelin receptor blockers in the treatment of primary pulmonary arterial hypertension]. | Kardiologiia 20070101 |
Management of pulmonary arterial hypertension associated with congenital heart disease. | Romanian journal of internal medicine = Revue roumaine de medecine interne 20070101 |
Tadalafil: the evidence for its clinical potential in the treatment of pulmonary arterial hypertension. | Core evidence 20070101 |
[Treatment of pulmonary arterial hypertension: endothelin-receptor antagonists]. | Deutsche medizinische Wochenschrift (1946) 20061208 |
Endothelin receptor antagonism in pulmonary arterial hypertension--a role for selective ET(A) inhibition? | Current medical research and opinion 20061201 |
Medical therapies for chronic thromboembolic pulmonary hypertension: an evolving treatment paradigm. | Proceedings of the American Thoracic Society 20060901 |
Endothelin receptor antagonists. | Pharmacology & therapeutics 20060601 |
Profile of past and current clinical trials involving endothelin receptor antagonists: the novel '-sentan' class of drug. | Experimental biology and medicine (Maywood, N.J.) 20060601 |
Endothelin antagonism prevents diabetic retinopathy in NOD mice: a potential role of the angiogenic factor adrenomedullin. | Experimental biology and medicine (Maywood, N.J.) 20060601 |
Attenuation of proinflammatory gene expression and microcirculatory disturbances by endothelin A receptor blockade after orthotopic liver transplantation in pigs. | Surgery 20060101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060101 |
Ambrisentan, a non-peptide endothelin receptor antagonist. | Cardiovascular drug reviews 20060101 |
Drug Insight: endothelin-receptor antagonists for pulmonary arterial hypertension in systemic rheumatic diseases. | Nature clinical practice. Rheumatology 20051201 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20051001 |
Ambrisentan therapy for pulmonary arterial hypertension. | Journal of the American College of Cardiology 20050802 |
Ambrisentan for pulmonary arterial hypertension. | Future cardiology 20050701 |
[Emerging therapies for the treatment of pulmonary arterial hypertension]. | Herz 20050601 |
[Treatment algorithm for pulmonary arterial hypertension]. | Herz 20050601 |
Improvement of postischemic hepatic microcirculation after endothelinA receptor blockade--endothelin antagonism influences platelet-endothelium interactions. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20050201 |
Drug treatment of pulmonary arterial hypertension: current and future agents. | Drugs 20050101 |
Effects of ET(A) receptor antagonism on proinflammatory gene expression and microcirculation following hepatic ischemia/reperfusion. | Microcirculation (New York, N.Y. : 1994) 20050101 |
Changes of vasoregulatory gene expression following hepatic ischemia/reperfusion and treatment with endothelin-A receptor blockade. | Journal of cardiovascular pharmacology 20041101 |
Endothelin-A receptor blockade improves postischemic hepatic microhemodynamics. | Journal of cardiovascular pharmacology 20041101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20041001 |
Endothelin receptor antagonists in pulmonary arterial hypertension. | Journal of the American College of Cardiology 20040616 |
Endothelin receptor antagonists are not beneficial in the therapy of acute experimental pancreatitis. | Langenbeck's archives of surgery 20040601 |
Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists. | Journal of medicinal chemistry 20040520 |
Influence of a selective endothelin(A) receptor antagonist on the quantitative mRNA expression and the immunohistochemistry of vasoactive mediators after pancreas transplantation. | Transplantation proceedings 20030901 |
Cerebrovascular characterization of the novel nonpeptide endothelin-A receptor antagonist LU 208075. | Clinical neuropharmacology 20030101 |
Ambrisentan (Myogen). | Current opinion in investigational drugs (London, England : 2000) 20021001 |
Administration of a selective endothelin-a receptor antagonist (BSF 208075) improves hepatic warm ischemia/reperfusion injury in pigs. | Transplantation proceedings 20020901 |
Effect of the novel endothelin(A) receptor antagonist LU 208075 on contraction and relaxation of isolated rat basilar artery. | Clinical science (London, England : 1979) 20020801 |
Endothelin A-receptor blockade in experimental diabetes improves glucose balance and gastrointestinal function. | Clinical science (London, England : 1979) 20020801 |