Eniporide
| Title | Journal |
|---|---|
| Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitable profile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat. | Journal of medicinal chemistry 20120823 |
| Functional observational battery and motor activity in rats after single administration of two NHE 1 inhibitors. | Toxicology and applied pharmacology 20051101 |
| Population pharmacokinetics of eniporide and its metabolite in healthy subjects and patients with acute myocardial infarction. | Journal of clinical pharmacology 20050601 |
| Myocardial protection at a crossroads: the need for translation into clinical therapy. | Circulation research 20040723 |
| Effect of the Na+/H+ exchange inhibitor eniporide on cardiac performance and myocardial high energy phosphates in pigs subjected to cardioplegic arrest. | The Annals of thoracic surgery 20040201 |
| Mice with a null mutation in the NHE1 Na+-H+ exchanger are resistant to cardiac ischemia-reperfusion injury. | Circulation research 20031017 |
| Na+ overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+ exchange blockers EIPA, cariporide and eniporide. | Molecular and cellular biochemistry 20030801 |
| An overview of inhibitors of Na(+)/H(+) exchanger. | European journal of medicinal chemistry 20030601 |
| Na+/H+ exchange inhibition with cardioplegia reduces cytosolic [Ca2+] and myocardial damage after cold ischemia. | Journal of cardiovascular pharmacology 20030501 |
| Zoniporide: a potent and highly selective inhibitor of human Na(+)/H(+) exchanger-1. | European journal of pharmacology 20020906 |
| Sodium/hydrogen-exchanger inhibition during cardioplegic arrest and cardiopulmonary bypass: an experimental study. | The Journal of thoracic and cardiovascular surgery 20020501 |
| In vitro and in vivo pharmacology of a structurally novel Na+-H+ exchange inhibitor, T-162559. | British journal of pharmacology 20020401 |
| Clinical trials update: highlights of the scientific sessions of the XXIII Congress of the European Society of Cardiology--WARIS II, ESCAMI, PAFAC, RITZ-1 and TIME. | European journal of heart failure 20011201 |
| The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. | Journal of the American College of Cardiology 20011115 |
| Arylcyclopropanecarboxyl guanidines as novel, potent, and selective inhibitors of the sodium hydrogen exchanger isoform-1. | Journal of medicinal chemistry 20010927 |
| Na(+)/H(+) exchange inhibition prevents endothelial dysfunction after I/R injury. | American journal of physiology. Heart and circulatory physiology 20010901 |
| Potent and selective inhibition of the human Na+/H+ exchanger isoform NHE1 by a novel aminoguanidine derivative T-162559. | European journal of pharmacology 20010518 |
| Discovery of zoniporide: a potent and selective sodium-hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility. | Bioorganic & medicinal chemistry letters 20010326 |
| The myocardial Na+/H+ exchanger: a potential therapeutic target for the prevention of myocardial ischaemic and reperfusion injury and attenuation of postinfarction heart failure. | Drugs 20010101 |