Hexadecanoic acid, 2-bromo-
| Title | Journal |
|---|---|
| Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity. | Molecular & cellular proteomics : MCP 20121201 |
| Amino-terminal cysteine residues differentially influence RGS4 protein plasma membrane targeting, intracellular trafficking, and function. | The Journal of biological chemistry 20120817 |
| Plasma membrane localization is required for RasA-mediated polarized morphogenesis and virulence of Aspergillus fumigatus. | Eukaryotic cell 20120801 |
| RING finger palmitoylation of the endoplasmic reticulum Gp78 E3 ubiquitin ligase. | FEBS letters 20120730 |
| Protein palmitoylation inhibition by 2-bromopalmitate alters gliding, host cell invasion and parasite morphology in Toxoplasma gondii. | Molecular and biochemical parasitology 20120701 |
| A highly conserved cytoplasmic cysteine residue in the α4 nicotinic acetylcholine receptor is palmitoylated and regulates protein expression. | The Journal of biological chemistry 20120629 |
| Myocardial macronutrient transporter adaptations in the adult pregestational female intrauterine and postnatal growth-restricted offspring. | American journal of physiology. Endocrinology and metabolism 20120601 |
| A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death. | American journal of physiology. Endocrinology and metabolism 20120601 |
| Palmitoylation of MPP1 (membrane-palmitoylated protein 1)/p55 is crucial for lateral membrane organization in erythroid cells. | The Journal of biological chemistry 20120601 |
| The stress-induced cytokine interleukin-6 decreases the inhibition/excitation ratio in the rat temporal cortex via trans-signaling. | Biological psychiatry 20120401 |
| Identification, organ expression and ligand-dependent expression levels of peroxisome proliferator activated receptors in grass carp (Ctenopharyngodon idella). | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301 |
| Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking. | Neuron 20120209 |
| Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling. | BMC cell biology 20120101 |
| Fatty acids-stress attenuates gluconeogenesis induction and glucose production in primary hepatocytes. | Lipids in health and disease 20120101 |
| In Vitro and In Vivo Characterizations of Chiglitazar, a Newly Identified PPAR Pan-Agonist. | PPAR research 20120101 |
| Short-term effects of palmitate and 2-bromopalmitate on the lipolytic activity of rat adipocytes. | Life sciences 20110926 |
| Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains. | Cancer biology & therapy 20110901 |
| Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. | Environmental health perspectives 20110801 |
| S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95. | Neuron 20110714 |
| Ion channel regulation by protein palmitoylation. | The Journal of biological chemistry 20110318 |
| A dual action of saturated fatty acids on electrical activity in rat pancreatic β-cells. Role of volume-regulated anion channel and KATP channel currents. | The Journal of physiology 20110315 |
| Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. | The Journal of biological chemistry 20110218 |
| Short-term regulation of adiponectin secretion in rat adipocytes. | Physiological research 20110101 |
| CDK5 is essential for soluble amyloid β-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton. | PloS one 20110101 |
| Fatty acid and peptide profiles in plasma membrane and membrane rafts of PUFA supplemented RAW264.7 macrophages. | PloS one 20110101 |
| Chronic effects of palmitate overload on nutrient-induced insulin secretion and autocrine signalling in pancreatic MIN6 beta cells. | PloS one 20110101 |
| Differential palmit(e)oylation of Wnt1 on C93 and S224 residues has overlapping and distinct consequences. | PloS one 20110101 |
| The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2. | PloS one 20110101 |
| Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels. | The Journal of biological chemistry 20101022 |
| Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease. | Neurobiology of disease 20101001 |
| Palmitoylation of human FasL modulates its cell death-inducing function. | Cell death & disease 20101001 |
| Multiple palmitoyltransferases are required for palmitoylation-dependent regulation of large conductance calcium- and voltage-activated potassium channels. | The Journal of biological chemistry 20100730 |
| Interplay of palmitoylation and phosphorylation in the trafficking and localization of phosphodiesterase 10A: implications for the treatment of schizophrenia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100707 |
| Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. | Journal of lipid research 20100601 |
| Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. | PLoS genetics 20100601 |
| Golgi-specific DHHC zinc finger protein GODZ mediates membrane Ca2+ transport. | The Journal of biological chemistry 20100212 |
| Palmitoylation supports the association of tetraspanin CD63 with CD9 and integrin alphaIIbbeta3 in activated platelets. | Thrombosis research 20100201 |
| Membrane-initiated estradiol signaling increases tyrosine hydroxylase promoter activity with ER alpha in PC12 cells. | Journal of neurochemistry 20100101 |
| Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas. | PloS one 20100101 |
| Eicosapentaenoic acid inhibits endothelial cell migration in vitro. | Journal of angiogenesis research 20100101 |
| Localized fetomaternal hyperglycemia: spatial and kinetic definition by positron emission tomography. | PloS one 20100101 |
| Palmitic acid analogs exhibit nanomolar binding affinity for the HIV-1 CD4 receptor and nanomolar inhibition of gp120-to-CD4 fusion. | PloS one 20100101 |
| Palmitate and insulin synergistically induce IL-6 expression in human monocytes. | Cardiovascular diabetology 20100101 |
| Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43. | PloS one 20100101 |
| Reversible, temperature-dependent supramolecular assembly of aquaporin-4 orthogonal arrays in live cell membranes. | Biophysical journal 20091202 |
| Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity. | Journal of lipid research 20091201 |
| Role of PSD95 in membrane association and catalytic activity of nNOSalpha in nitrergic varicosities in mice gut. | American journal of physiology. Gastrointestinal and liver physiology 20091001 |
| The effects of 2-bromopalmitate on the fatty acid composition in differentiating adipocytes of red sea bream (Pagrus major). | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20090401 |
| Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus. | Molecular microbiology 20090401 |
| 2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro. | Journal of lipid research 20090201 |
| Protein palmitoylation regulates osteoblast differentiation through BMP-induced osterix expression. | PloS one 20090101 |
| Neuroligin1: a cell adhesion molecule that recruits PSD-95 and NMDA receptors by distinct mechanisms during synaptogenesis. | Neural development 20090101 |
| The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathway. | PloS one 20090101 |
| PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease. | PPAR research 20090101 |
| Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport. | The Journal of biological chemistry 20081128 |
| Use of micellar electrokinetic chromatography to measure palmitoylation of a peptide. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115 |
| Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle. | Endocrinology 20081101 |
| Molecular characterization of peroxisome proliferator-activated receptors (PPARs) and their gene expression in the differentiating adipocytes of red sea bream Pagrus major. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20081101 |
| Mesodermal fate decisions of a stem cell: the Wnt switch. | Cellular and molecular life sciences : CMLS 20080901 |
| Long chain fatty acid uptake in vivo: comparison of [125I]-BMIPP and [3H]-bromopalmitate. | Lipids 20080801 |
| Polyunsaturated fatty acids block platelet-activating factor-induced phosphatidylinositol 3 kinase/Akt-mediated apoptosis in intestinal epithelial cells. | American journal of physiology. Gastrointestinal and liver physiology 20080501 |
| Excitotoxic loss of post-synaptic sites is distinct temporally and mechanistically from neuronal death. | Journal of neurochemistry 20080101 |
| Palmitoylation of POTE family proteins for plasma membrane targeting. | Biochemical and biophysical research communications 20071123 |
| The role of an intracellular cysteine stretch in the sorting of the type II Na/phosphate cotransporter. | Biochimica et biophysica acta 20070901 |
| Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family. | Neuroscience 20070824 |
| Shuttling of G protein subunits between the plasma membrane and intracellular membranes. | The Journal of biological chemistry 20070817 |
| Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells. | The Journal of endocrinology 20070801 |
| Role of LRAT on the retinoid isomerase activity and membrane association of Rpe65. | The Journal of biological chemistry 20070720 |
| S-acylation regulates Kv1.5 channel surface expression. | American journal of physiology. Cell physiology 20070701 |
| Regulation of FAT/CD36 mRNA gene expression by long chain fatty acids in the differentiated 3T3-L1 cells. | Pediatric surgery international 20070701 |
| Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase. | The Journal of biological chemistry 20070330 |
| Multiple peroxisome proliferator-activated receptor beta subtypes from Atlantic salmon (Salmo salar). | Journal of molecular endocrinology 20070301 |
| Malonyl coenzyme A affects insulin-stimulated glucose transport in myotubes. | Archives of physiology and biochemistry 20070201 |
| Metabolic Functions of Peroxisome Proliferator-Activated Receptor beta/delta in Skeletal Muscle. | PPAR research 20070101 |
| R7-binding protein targets the G protein beta 5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain. | BMC biochemistry 20070101 |
| Homeostatic plasticity during alcohol exposure promotes enlargement of dendritic spines. | The European journal of neuroscience 20061201 |
| Acylation of CD44 and its association with lipid rafts are required for receptor and hyaluronan endocytosis. | The Journal of biological chemistry 20061110 |
| Use of analogs and inhibitors to study the functional significance of protein palmitoylation. | Methods (San Diego, Calif.) 20061001 |
| Fluorescence-based methods to image palmitoylated proteins. | Methods (San Diego, Calif.) 20061001 |
| CYP4A11 is repressed by retinoic acid in human liver cells. | FEBS letters 20060612 |
| Distinct subcellular localization for constitutive and agonist-modulated palmitoylation of the human delta opioid receptor. | The Journal of biological chemistry 20060609 |
| PPARgamma agonist induced cardiac enlargement is associated with reduced fatty acid and increased glucose utilization in myocardium of Wistar rats. | European journal of pharmacology 20060524 |
| Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes. | Traffic (Copenhagen, Denmark) 20060301 |
| Essential contribution of the ligand-binding beta B/beta C loop of PDZ1 and PDZ2 in the regulation of postsynaptic clustering, scaffolding, and localization of postsynaptic density-95. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060118 |
| Biochemical analyses of the Wrch atypical Rho family GTPases. | Methods in enzymology 20060101 |
| The effect of insulin on the intracellular distribution of 14(R,S)-[18F]Fluoro-6-thia-heptadecanoic acid in rats. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20060101 |
| The PTI1-like kinase ZmPti1a from maize (Zea mays L.) co-localizes with callose at the plasma membrane of pollen and facilitates a competitive advantage to the male gametophyte. | BMC plant biology 20060101 |
| A live cell, image-based approach to understanding the enzymology and pharmacology of 2-bromopalmitate and palmitoylation. | Methods in enzymology 20060101 |
| Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion. | Cell and tissue research 20051101 |
| A new retinoid-like compound that activates peroxisome proliferator-activated receptors and lowers blood glucose in diabetic mice. | Biological & pharmaceutical bulletin 20050701 |
| Structural organization and interactions of transmembrane domains in tetraspanin proteins. | BMC structural biology 20050101 |
| The role of palmitoylation in functional expression of nicotinic alpha7 receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041117 |
| Effect of dexamethasone, 2-bromopalmitate and clofibrate on L-FABP mediated hepatoma proliferation. | The Journal of pharmacy and pharmacology 20040901 |
| Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. | The Journal of biological chemistry 20040806 |
| Design, synthesis, and evaluation of a new class of noncyclic 1,3-dicarbonyl compounds as PPARalpha selective activators. | Bioorganic & medicinal chemistry letters 20040705 |
| Direct desaturation of free myristic acid by hen liver microsomal Delta9-desaturase without prior activation to myristoyl-CoA derivative. | Journal of agricultural and food chemistry 20040519 |
| S-palmitoylation modulates human estrogen receptor-alpha functions. | Biochemical and biophysical research communications 20040409 |
| Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking. | The Biochemical journal 20040115 |
| Palmitate-induced Ca2+-signaling in pancreatic beta-cells. | Molecular and cellular endocrinology 20031230 |
| Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation. | Blood 20031201 |
| Novel roles for palmitoylation of Ras in IL-1 beta-induced nitric oxide release and caspase 3 activation in insulin-secreting beta cells. | Biochemical pharmacology 20031101 |
| Palmitate potentiation of glucose-induced insulin release: a study using 2-bromopalmitate. | Metabolism: clinical and experimental 20031001 |
| Skeletal muscle cells from insulin-resistant (non-diabetic) individuals are susceptible to insulin desensitization by palmitate. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20031001 |
| Regulation of leptin secretion from white adipocytes by free fatty acids. | American journal of physiology. Endocrinology and metabolism 20030901 |
| Sterol carrier protein-2/sterol carrier protein-x expression differentially alters fatty acid metabolism in L cell fibroblasts. | Journal of lipid research 20030901 |
| Saturated fatty acid-induced apoptosis in MDA-MB-231 breast cancer cells. A role for cardiolipin. | The Journal of biological chemistry 20030822 |
| Protein acylation in the inhibition of insulin secretion by norepinephrine, somatostatin, galanin, and PGE2. | American journal of physiology. Endocrinology and metabolism 20030801 |
| Lipid- and protein-mediated multimerization of PSD-95: implications for receptor clustering and assembly of synaptic protein networks. | Journal of cell science 20030801 |
| Nutritional regulation and role of peroxisome proliferator-activated receptor delta in fatty acid catabolism in skeletal muscle. | Biochimica et biophysica acta 20030704 |
| Characterization of human palmitoyl-acyl transferase activity using peptides that mimic distinct palmitoylation motifs. | The Biochemical journal 20030701 |
| Palmitate modulates the early steps of insulin signalling pathway in pancreatic islets. | FEBS letters 20030605 |
| Assembly and secretion of very low density lipoproteins containing apolipoprotein B48 in transfected McA-RH7777 cells. Lack of evidence that palmitoylation of apolipoprotein B48 is required for lipoprotein secretion. | The Journal of biological chemistry 20030418 |
| Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane. | Biochemistry 20030211 |
| Phosphorylation of FcgammaRIIA is required for the receptor-induced actin rearrangement and capping: the role of membrane rafts. | Journal of cell science 20030201 |
| PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation. | Journal of lipid research 20030201 |
| Involvement of Src family protein tyrosine kinases in Ca(2+) sensitization of coronary artery contraction mediated by a sphingosylphosphorylcholine-Rho-kinase pathway. | Circulation research 20021115 |
| Intracellular fatty acid downregulates ob gene expression in 3T3-L1 adipocytes. | Biochemical and biophysical research communications 20021011 |
| A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity. | Analytical biochemistry 20020901 |
| Distance-dependent cellular palmitoylation of de-novo-designed sequences and their translocation to plasma membrane subdomains. | Journal of cell science 20020801 |
| Evaluation of free fatty acid metabolism in vivo. | Annals of the New York Academy of Sciences 20020601 |
| Synaptic strength regulated by palmitate cycling on PSD-95. | Cell 20020322 |
| Sensitive and rapid analysis of protein palmitoylation with a synthetic cell-permeable mimic of SRC oncoproteins. | Journal of the American Chemical Society 20020320 |
| Evidence for selective induction of phosphoenolpyruvate carboxykinase gene expression by unsaturated and nonmetabolized fatty acids in adipocytes. | Journal of cellular biochemistry 20020101 |
| Up-regulation of uncoupling protein 3 gene expression by fatty acids and agonists for PPARs in L6 myotubes. | Endocrinology 20011001 |
| Palmitoylation-dependent control of degradation, life span, and membrane expression of the CCR5 receptor. | The Journal of biological chemistry 20010824 |
| Regulation of fatty acid oxidation and glucose metabolism in rat soleus muscle: effects of AICAR. | American journal of physiology. Endocrinology and metabolism 20010801 |
| Inhibition of gap-junctional communication induces the trans-differentiation of osteoblasts to an adipocytic phenotype in vitro. | The Journal of biological chemistry 20010427 |
| Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids. | Diabetes 20010201 |
| Abundant expression of uncoupling protein-2 in the small intestine: up-regulation by dietary fish oil and fibrates. | Biochimica et biophysica acta 20010115 |
| Opposite effects of androgens and estrogens on adipogenesis in rat preadipocytes: evidence for sex and site-related specificities and possible involvement of insulin-like growth factor 1 receptor and peroxisome proliferator-activated receptor gamma2. | Endocrinology 20000201 |
| Regulation of rat liver apolipoprotein A-I, apolipoprotein A-II and acyl-coenzyme A oxidase gene expression by fibrates and dietary fatty acids. | European journal of biochemistry 19950815 |
| Palmitoylation regulates 17β-estradiol-induced estrogen receptor-α degradation and transcriptional activity. | Molecular endocrinology (Baltimore, Md.) |