Sb 225002
Title | Journal |
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Adiponectin promotes human jaw bone marrow mesenchymal stem cell chemotaxis via CXCL1 and CXCL8. | Journal of cellular and molecular medicine 20170701 |
Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2. | Journal of medicinal chemistry 20141023 |
Chemokine receptor antagonists. | Journal of medicinal chemistry 20121126 |
The role of CXCR2 chemokine receptors in the oral squamous cell carcinoma. | Investigational new drugs 20120801 |
Epigenetic augmentation of the macrophage inflammatory protein 2/C-X-C chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits neuropathic pain. | The Journal of pharmacology and experimental therapeutics 20120301 |
CXCR2 antagonists block the N-Ac-PGP-induced neutrophil influx in the airways of mice, but not the production of the chemokine CXCL1. | European journal of pharmacology 20111015 |
Simvastatin regulates CXC chemokine formation in streptococcal M1 protein-induced neutrophil infiltration in the lung. | American journal of physiology. Lung cellular and molecular physiology 20110601 |
Simvastatin antagonizes CD40L secretion, CXC chemokine formation, and pulmonary infiltration of neutrophils in abdominal sepsis. | Journal of leukocyte biology 20110501 |
CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions. | The Journal of clinical investigation 20110401 |
Chemokine-related gene expression in the brain following ischemic stroke: no role for CXCR2 in outcome. | Brain research 20110204 |
Cardiac glycosides are potent inhibitors of interferon-β gene expression. | Nature chemical biology 20110101 |
Mechanisms involved in IL-6-induced muscular mechanical hyperalgesia in mice. | Pain 20101101 |
The effects of the selective and non-peptide CXCR2 receptor antagonist SB225002 on acute and long-lasting models of nociception in mice. | European journal of pain (London, England) 20100101 |
Structural optimization of a CXCR2-directed antagonist that indirectly inhibits gamma-secretase and reduces Abeta. | Bioorganic & medicinal chemistry 20091201 |
The angiogenic effect of probiotic Bacillus polyfermenticus on human intestinal microvascular endothelial cells is mediated by IL-8. | American journal of physiology. Gastrointestinal and liver physiology 20091101 |
[Selective non-peptide CXCR2 antagonist SB225002 inhibits choroidal neovascularization in rat model]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20090801 |
Novel role of CXCR2 in regulation of gamma-secretase activity. | ACS chemical biology 20081219 |
The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice. | Journal of leukocyte biology 20081001 |
Hepatocyte signaling through CXC chemokine receptor-2 is detrimental to liver recovery after ischemia/reperfusion in mice. | Hepatology (Baltimore, Md.) 20081001 |
CXCR2 chemokine receptor antagonism enhances DOP opioid receptor function via allosteric regulation of the CXCR2-DOP receptor heterodimer. | The Biochemical journal 20080601 |
Secreted protein acidic, rich in cysteine induces pulp cell migration via alphavbeta3 integrin and extracellular signal-regulated kinase. | Oral diseases 20080501 |
Comparison of N,N'-diarylsquaramides and N,N'-diarylureas as antagonists of the CXCR2 chemokine receptor. | Bioorganic & medicinal chemistry letters 20070315 |
Differential calcium signaling in dairy cows with specific CXCR1 genotypes potentially related to interleukin-8 receptor functionality. | Immunogenetics 20070101 |
Regulation of matrix metalloproteinase-9 release from IL-8-stimulated human neutrophils. | Journal of leukocyte biology 20050701 |
IL-8 increases transmission of HIV type 1 in cervical explant tissue. | AIDS research and human retroviruses 20050301 |
Beta 2-adrenergic receptor regulation of human neutrophil function is sexually dimorphic. | British journal of pharmacology 20041201 |
Rabbit neutrophil chemotactic protein (NCP) activates both CXCR1 and CXCR2 and is the functional homologue for human CXCL6. | Biochemical pharmacology 20041115 |
Cloning and pharmacological characterization of CXCR1 and CXCR2 from Macaca fascicularis. | The Journal of pharmacology and experimental therapeutics 20040701 |
Characterization of the molecular interactions of interleukin-8 (CXCL8), growth related oncogen alpha (CXCL1) and a non-peptide antagonist (SB 225002) with the human CXCR2. | Biochemical pharmacology 20030301 |
Nonpeptide CXCR2 antagonist prevents neutrophil accumulation in hyperoxia-exposed newborn rats. | The Journal of pharmacology and experimental therapeutics 20011001 |
Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration. | The Journal of biological chemistry 19980424 |