Lomitapide
Title | Journal |
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Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study. | Lancet (London, England) 20130105 |
Multiple functions of microsomal triglyceride transfer protein. | Nutrition & metabolism 20120101 |
Mipomersen: evidence-based review of its potential in the treatment of homozygous and severe heterozygous familial hypercholesterolemia. | Core evidence 20120101 |
New clinical perspectives of hypolipidemic drug therapy in severe hypercholesterolemia. | Current medicinal chemistry 20120101 |
Familial hypercholesterolemia: present and future management. | Current cardiology reports 20111201 |
Lomitapide. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20111001 |
Inhibition of microsomal triglyceride transfer protein improves insulin sensitivity and reduces atherogenic risk in Zucker fatty rats. | Clinical and experimental pharmacology & physiology 20110501 |
Lomitapide, a microsomal triglyceride transfer protein inhibitor for the treatment of hypercholesterolemia. | IDrugs : the investigational drugs journal 20100201 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20090601 |
Dyslipidemia and cardiovascular diseases. | Current opinion in lipidology 20090401 |
Novel nonstatin strategies to lower low-density lipoprotein cholesterol. | Current atherosclerosis reports 20090101 |
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. | Nature clinical practice. Cardiovascular medicine 20080801 |
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. | The New England journal of medicine 20070111 |
5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP. | Bioorganic & medicinal chemistry letters 20041018 |
Atorvastatin increases hepatic fatty acid beta-oxidation in sucrose-fed rats: comparison with an MTP inhibitor. | European journal of pharmacology 20021129 |
A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors. | Journal of medicinal chemistry 20010315 |