5-Chlorouracil
Title | Journal |
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Protonation preferentially stabilizes minor tautomers of the halouracils: IRMPD action spectroscopy and theoretical studies. | Journal of the American Society for Mass Spectrometry 20120901 |
A spectroscopic investigations of anticancer drugs binding to bovine serum albumin. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120301 |
A rapid HPLC-ESI-MS/MS method for determination of dihydrouracil/uracil ratio in plasma: evaluation of toxicity to 5-flurouracil in patients with gastrointestinal cancer. | Therapeutic drug monitoring 20120201 |
Benzene metabolite 1,2,4-benzenetriol induces halogenated DNA and tyrosines representing halogenative stress in the HL-60 human myeloid cell line. | Environmental health perspectives 20120101 |
Electron transfer processes in potassium collisions with 5-fluorouracil and 5-chlorouracil. | Physical chemistry chemical physics : PCCP 20111228 |
Chemical evolution of a bacterium's genome. | Angewandte Chemie (International ed. in English) 20110725 |
Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study. | Cancer chemotherapy and pharmacology 20110501 |
Photoelectron spectroscopic study of the negative ions of 4-thiouracil and 2,4-dithiouracil. | The Journal of chemical physics 20110221 |
Photoelectron spectroscopic studies of 5-halouracil anions. | The Journal of chemical physics 20110107 |
Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention. | Journal of clinical biochemistry and nutrition 20110101 |
Anti-proliferation effects of Sirolimus sustained delivery film in rabbit glaucoma filtration surgery. | Molecular vision 20110101 |
Epigenomics in environmental health. | Frontiers in genetics 20110101 |
Characterization of a novel lymph node metastasis model from human colonic cancer and its preclinical use for comparison of anti-metastatic efficacy between oral S-1 and UFT/ LV. | Cancer science 20100801 |
Polymerase incorporation and miscoding properties of 5-chlorouracil. | Chemical research in toxicology 20100419 |
A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma. | Biomedical chromatography : BMC 20100401 |
Paclitaxel inhibits growth, migration and collagen production of human Tenon's fibroblasts--potential use in drug-eluting glaucoma drainage devices. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20100201 |
Comparative study of HOCl-inflicted damage to bacterial DNA ex vivo and within cells. | Archives of biochemistry and biophysics 20100115 |
[Markers of chloric acid (I) in biological systems--identification and properties]. | Postepy biochemii 20100101 |
pH-Dependent configurations of a 5-chlorouracil-guanine base pair. | Biochemistry 20091201 |
Base pairing configuration and stability of an oligonucleotide duplex containing a 5-chlorouracil-adenine base pair. | Biochemistry 20090811 |
Retrospective analysis of S-1 monotherapy in patients with metastatic colorectal cancer after failure to fluoropyrimidine and irinotecan or to fluoropyrimidine, irinotecan and oxaliplatin. | Japanese journal of clinical oncology 20090501 |
Significance of 5-fluorouracil-related enzyme activities in predicting sensitivity to 5-fluorouracil in bladder carcinoma. | Anticancer research 20090401 |
Reactive oxygen and nitrogen species induce protein and DNA modifications driving arthrofibrosis following total knee arthroplasty. | Fibrogenesis & tissue repair 20090101 |
Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma. | Investigative ophthalmology & visual science 20080701 |
Examination of hypochlorous acid-induced damage to cytosine residues in a CpG dinucleotide in DNA. | Chemical research in toxicology 20080601 |
[Clinical benefit of S-1 in metastatic breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060601 |
Myeloperoxidase generates 5-chlorouracil in human atherosclerotic tissue: a potential pathway for somatic mutagenesis by macrophages. | The Journal of biological chemistry 20060210 |
Evaluation of novel one-electron reduction with metal in DNA. | Nucleic acids symposium series (2004) 20060101 |
Hydrophilic interaction liquid chromatography-APCI-mass spectrometry determination of 5-fluorouracil in plasma and tissues. | Journal of pharmaceutical and biomedical analysis 20050715 |
Measurement of drug release from microcarriers by microdialysis. | Journal of pharmaceutical sciences 20050701 |
Influence of halogenation on the properties of uracil and its noncovalent interactions with alkali metal ions. Threshold collision-induced dissociation and theoretical studies. | Journal of the American Chemical Society 20041215 |
Thymidylate synthase predictive power is overcome by irinotecan combination therapy with S-1 for gastric cancer. | British journal of cancer 20041004 |
Synthesis and characterization of oligonucleotides containing 5-chlorocytosine. | Chemical research in toxicology 20040901 |
Phase I and pharmacokinetic study of the oral fluoropyrimidine S-1 on a once-daily-for-28-day schedule in patients with advanced malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040801 |
Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 1: discovery of novel orally active inhibitors of human thymidine phosphorylase. | Bioorganic & medicinal chemistry 20040701 |
Alternate-day oral therapy with TS-1 for advanced gastric cancer. | International journal of clinical oncology 20040601 |
Electron attachment to chlorouracil: a comparison between 6-ClU and 5-ClU. | The Journal of chemical physics 20040108 |
Phase I study of irinotecan and S-1 combination therapy in patients with metastatic gastric cancer. | International journal of clinical oncology 20031201 |
5-Chlorouracil, a marker of DNA damage from hypochlorous acid during inflammation. A gas chromatography-mass spectrometry assay. | The Journal of biological chemistry 20030829 |
Phagocytes produce 5-chlorouracil and 5-bromouracil, two mutagenic products of myeloperoxidase, in human inflammatory tissue. | The Journal of biological chemistry 20030627 |
Analytical and pharmacokinetic studies with 5-chloro-2'-deoxycytidine. | Biochemical pharmacology 20021115 |
Loss of oxidized and chlorinated bases in DNA treated with reactive oxygen species: implications for assessment of oxidative damage in vivo. | Biochemical and biophysical research communications 20020830 |
Detection and quantification of 5-chlorocytosine in DNA by stable isotope dilution and gas chromatography/negative ion chemical ionization/mass spectrometry. | Chemical research in toxicology 20020201 |
An improved resazurin-based cytotoxicity assay for hepatic cells. | Cell biology and toxicology 20020101 |
N(1)-C(5')-linked dimer hydrates of 5-substituted uracils produced by anodic oxidation in aqueous solution. | The Journal of organic chemistry 20010406 |
Simultaneous determination of flucytosine and fluorouracil in human plasma by high-performance liquid chromatography. | Biomedical chromatography : BMC 20010401 |
Determination of 5-fluorouracil in environmental samples by solid-phase extraction and high-performance liquid chromatography with ultraviolet detection. | Journal of chromatography. B, Biomedical sciences and applications 20010105 |
Synthesis of 5-chloro-1-(2,3-dideoxy-3-fluoro-beta-D-glycero-hex-2- enopyranose-4-ulosyl)uracil as potential anticancer/antiviral agent. | Nucleosides, nucleotides & nucleic acids 20010101 |
Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii. | Biochemical pharmacology 19940817 |
Synthesis, structure, and antitumor and antiviral activities of a series of 5-halouridine cyclic 3',5'-monophosphates. | Journal of medicinal chemistry 19860401 |
Interaction of monoclonal antibodies directed against bromodeoxyuridine with pyrimidine bases, nucleosides, and DNA. | Journal of immunology (Baltimore, Md. : 1950) 19860301 |