Home Other Building Blocks 2-Hydroxyadenosine

2-Hydroxyadenosine

CAS No.:
1818-71-9
Catalog Number:
AG002349
Molecular Formula:
C10H13N5O5
Molecular Weight:
283.2407
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
95+%
1 week
United States
$53
- +
Product Description
Catalog Number:
AG002349
Chemical Name:
2-Hydroxyadenosine
CAS Number:
1818-71-9
Molecular Formula:
C10H13N5O5
Molecular Weight:
283.2407
MDL Number:
MFCD01863406
IUPAC Name:
6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-2-one
InChI:
InChI=1S/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
InChI Key:
MIKUYHXYGGJMLM-UUOKFMHZSA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1[nH]c(=O)nc2N
Properties
Complexity:
544  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
283.092g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
283.244g/mol
Monoisotopic Mass:
283.092g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
153A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3  
Literature
Title Journal
[New processing procedure for Croton tiglium with study on comparison of Croton tiglium and processed product]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120301
Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides. Bioorganic & medicinal chemistry 20111001
Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates. Journal of medicinal chemistry 20110825
Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation. The Journal of organic chemistry 20100305
Pyrazolo[3,4-d]pyrimidine ribonucleosides related to 2-aminoadenosine and isoguanosine: synthesis, deamination and tautomerism. Organic & biomolecular chemistry 20070921
Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling. BMC biochemistry 20070101
Mismatch discrimination of base-modified nucleic acids and their constituents: non-Watson-Crick base pairing induced by tautomerization. Nucleosides, nucleotides & nucleic acids 20070101
RNA challenges for computational chemists. Biochemistry 20051011
Demonstration of an alternative mechanism for G-to-G cross-link formation. Journal of the American Chemical Society 20050126
Novel dinucleoside 5',5'-triphosphate cap analogues. Synthesis and affinity for murine translation factor eIF4E. Nucleosides, nucleotides & nucleic acids 20050101
Selective 226Ra2+ ionophores provided by self-assembly of guanosine and isoguanosine derivatives. Journal of the American Chemical Society 20041222
Nucleic acid analysis using an expanded genetic alphabet to quench fluorescence. Journal of the American Chemical Society 20040414
Effect of 2'-deoxyisoguanosine on the growth of human tumor and normal cell lines. Eksperimental'naia onkologiia 20040301
Alkaline hydrolysis of cladribine. Die Pharmazie 20030201
Oligonucleotides incorporating N7-(2'-deoxy-beta-D-erythro-pentofuranosyl)isoguanine. Nucleosides, nucleotides & nucleic acids 20030101
Chemical stability of 2'-deoxy-5-methylisocytidine during oligodeoxynucleotide synthesis and deprotection. Nucleosides, nucleotides & nucleic acids 20020101
Stability and structure of RNA duplexes containing isoguanosine and isocytidine. Journal of the American Chemical Society 20010221
Quadruplex and pentaplex self-assemblies of oligonucleotides containing short runs of 8-aza-7-deaza-2'-deoxyisoguanosine or 2'-deoxyisoguanosine. Bioconjugate chemistry 20010101
Properties