Home Other Building Blocks Proflavine hemisulfate hydrate

Proflavine hemisulfate hydrate

CAS No.:
1811-28-5
Catalog Number:
AG0022OQ
Molecular Formula:
C26H24N6O4S
Molecular Weight:
516.5716
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$25
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Product Description
Catalog Number:
AG0022OQ
Chemical Name:
Proflavine hemisulfate hydrate
CAS Number:
1811-28-5
Molecular Formula:
C26H24N6O4S
Molecular Weight:
516.5716
MDL Number:
MFCD00149650
IUPAC Name:
acridine-3,6-diamine;sulfuric acid
InChI:
InChI=1S/2C13H11N3.H2O4S/c2*14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;1-5(2,3)4/h2*1-7H,14-15H2;(H2,1,2,3,4)
InChI Key:
YADYXCVYLIKQJX-UHFFFAOYSA-N
SMILES:
OS(=O)(=O)O.Nc1ccc2c(c1)nc1c(c2)ccc(c1)N.Nc1ccc2c(c1)nc1c(c2)ccc(c1)N
EC Number:
217-320-3
UNII:
27V8M747VB
Properties
Complexity:
313  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
516.158g/mol
Formal Charge:
0
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0
Molecular Weight:
516.576g/mol
Monoisotopic Mass:
516.158g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
213A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Discrimination of benign and neoplastic mucosa with a high-resolution microendoscope (HRME) in head and neck cancer. Annals of surgical oncology 20121001
Intermolecular hydrogen bonds in hetero-complexes of biologically active aromatic molecules probed by the methods of vibrational spectroscopy. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120901
Visible light-driven NADH regeneration sensitized by proflavine for biocatalysis. Chembiochem : a European journal of chemical biology 20120618
Vital-dye enhanced fluorescence imaging of GI mucosa: metaplasia, neoplasia, inflammation. Gastrointestinal endoscopy 20120401
A C-di-GMP-proflavine-hemin supramolecular complex has peroxidase activity--implication for a simple colorimetric detection. Molecular bioSystems 20120301
Existence of a new emitting singlet state of proflavine: femtosecond dynamics of the excited state processes and quantum chemical studies in different solvents. The journal of physical chemistry. A 20120112
[Studies by means of 1H NMR spectroscopy of complex formation of aromatic biologically active compounds with antibiotic topotecan]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20120101
Large-scale symmetry-adapted perturbation theory computations via density fitting and Laplace transformation techniques: investigating the fundamental forces of DNA-intercalator interactions. The Journal of chemical physics 20111107
Fluorimetric study on the interaction between Norfloxacin and Proflavine hemisulphate. Journal of fluorescence 20110701
c-di-GMP can form remarkably stable G-quadruplexes at physiological conditions in the presence of some planar intercalators. Chemical communications (Cambridge, England) 20110428
Proflavine derivatives as fluorescent imaging agents of amyloid deposits. Bioorganic & medicinal chemistry letters 20110415
DNA binding of a proflavine derivative bearing a platinum hanging residue. Journal of inorganic biochemistry 20110401
[Energetics of complex formation of the DNA hairpin structure d(GCGAAGC) with aromatic ligands]. Biofizika 20110101
[Comparative sensitivity of liver monoamine oxidases of frog and whitefish to some tricyclic compounds]. Zhurnal evoliutsionnoi biokhimii i fiziologii 20110101
Magnetic field effect corroborated with docking study to explore photoinduced electron transfer in drug-protein interaction. The journal of physical chemistry. A 20101230
Synthesis, characterization and cytotoxicity studies of palladium(II)-proflavine complexes. Journal of inorganic biochemistry 20101101
Change of the binding mode of the DNA/proflavine system induced by ethanol. The journal of physical chemistry. B 20100701
The nature of the force-induced conformation transition of dsDNA studied by using single molecule force spectroscopy. Langmuir : the ACS journal of surfaces and colloids 20100615
Triple dye plus rubbing alcohol versus triple dye alone for umbilical cord care. Clinical pediatrics 20100101
1H and 13C NMR signal assignments of some new N,N'-diacyl proflavine derivatives. Magnetic resonance in chemistry : MRC 20090801
Photo-inducible cytotoxic and clastogenic activities of 3,6-di-substituted acridines obtained by acylation of proflavine. European journal of medicinal chemistry 20090601
Solution structure and thermodynamics of 2',5' RNA intercalation. Journal of the American Chemical Society 20090429
Interaction of small molecules with double-stranded RNA: spectroscopic, viscometric, and calorimetric study of hoechst and proflavine binding to PolyCG structures. DNA and cell biology 20090401
[Features of binding of proflavine to DNA at different DNA-ligand concentration ratios]. Biofizika 20090101
[Experimental study of proflavine acetate phototransformation processes]. Gigiena i sanitariia 20090101
Fluorophore labeling to monitor tRNA dynamics. Methods in enzymology 20090101
Electroanalytical study of proflavine intercalation in 5-methyl or inosine-containing amplicons. Analytical and bioanalytical chemistry 20081001
Role of the third strand in the binding of proflavine and pt-proflavine to poly(rA).2poly(rU): a thermodynamic and kinetic study. The journal of physical chemistry. B 20080612
Cytotoxic activity of proflavine diureas: synthesis, antitumor, evaluation and DNA binding properties of 1',1''-(acridin-3,6-diyl)-3',3''-dialkyldiureas. Bioorganic & medicinal chemistry 20080401
DNA binding by a new metallointercalator that contains a proflavine group bearing a hanging chelating unit. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
A randomised controlled trial of a double layer of Allevyn compared to Jellonet and proflavin as a tie-over dressing for small skin grafts. Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20080101
Skipjack tuna (Katsuwonus pelamis) liver monoamine oxidase: substrate-inhibitor analysis. Doklady. Biochemistry and biophysics 20080101
Protonation linked equilibria and apparent affinity constants: the thermodynamic profile of the alpha-chymotrypsin-proflavin interaction. European biophysics journal : EBJ 20071201
Ligand-transporter interaction in the AcrB multidrug efflux pump determined by fluorescence polarization assay. FEBS letters 20071016
Quantifying RNA-peptide interaction by single-quantum dot-based nanosensor: an approach for drug screening. Analytical chemistry 20071015
Synthesis and antileishmanial activity of 6-mono-substituted and 3,6-di-substituted acridines obtained by acylation of proflavine. European journal of medicinal chemistry 20071001
Characterization of the multidrug efflux regulator AcrR from Escherichia coli. Biochemical and biophysical research communications 20070914
On the origin of the decrease in stability of the DNA hairpin d(GCGAAGC) on complexation with aromatic drugs. Biophysical chemistry 20070801
Synthesis, DNA interaction, and cytotoxic activity of a novel proflavine-dithiazolidinone pharmacophore. Bioconjugate chemistry 20070101
A rare cause of breast mass that mimics carcinoma: Foreign body reaction to amorphous surgical material. Wiener klinische Wochenschrift 20070101
Catalytic properties of monoamine oxidase from mink (Mustela vison) liver. Doklady. Biochemistry and biophysics 20070101
[Comparative toxicity of photosensitizers in varying destruction]. Gigiena i sanitariia 20070101
Ethidium and proflavine binding to a 2',5'-linked RNA duplex. Journal of the American Chemical Society 20061206
Determination of the DNA-binding characteristics of ethidium bromide, proflavine, and cisplatin by flow injection analysis: usefulness in studies on antitumor drugs. Analytical biochemistry 20060815
Dye-induced aggregation of single stranded RNA: a mechanistic approach. Archives of biochemistry and biophysics 20060815
Physical nature of ethidium and proflavine interactions with nucleic acid bases in the intercalation plane. The journal of physical chemistry. B 20060518
Electrochemical and spectroscopic studies of the interaction of proflavine with DNA. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060301
Inhibiting protein-amyloid interactions with small molecules: a surface chemistry approach. Bioorganic & medicinal chemistry letters 20060215
Characterization of a two-gene operon epeRA involved in multidrug resistance in Streptomyces clavuligerus. Research in microbiology 20060101
Catalytic properties of monoamine oxidase from the lamprey Lampetrafluviatilis liver. Doklady. Biochemistry and biophysics 20060101
Fluorescence of acridinic dyes in anionic surfactant solution. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051001
A randomized study of 3 umbilical cord care regimens at home in thai neonates: comparison of time to umbilical cord separation, parental satisfaction and bacterial colonization. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20050701
Relaxation kinetics of the interaction between RNA and metal-intercalators: the Poly(A).Poly(U)/platinum-proflavine system. Archives of biochemistry and biophysics 20050515
Dendrimers with both polar and apolar nanocontainer characteristics. Journal of the American Chemical Society 20041208
Changes in newborn bathing practices may increase the risk for omphalitis. Clinical pediatrics 20041001
Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein. The EMBO journal 20040804
Management of ventral hernia after giant exomphalos with external pressure compression using helmet device. Journal of pediatric surgery 20040801
Assembly of an antiparallel homo-adenine DNA duplex by small-molecule binding. Journal of the American Chemical Society 20040721
Enzymatic behavior by intercalating molecules in a template-directed ligation reaction. Angewandte Chemie (International ed. in English) 20040402
Equilibria and kinetics of the intercalation of Pt-proflavine and proflavine into calf thymus DNA. Archives of biochemistry and biophysics 20031001
Proflavine acts as a Rev inhibitor by targeting the high-affinity Rev binding site of the Rev responsive element of HIV-1. Biochemistry 20030708
A biochemical logic gate using an enzyme and its inhibitor. Part II: The logic gate. Bio Systems 20030601
To dye or not to dye: a randomized, clinical trial of a triple dye/alcohol regime versus dry cord care. Pediatrics 20030101
Post-surgery vaginal packs. Journal of wound care 20021001
Synthesis and DNA interaction of a mixed proflavine-phenanthroline Tröger base. European journal of medicinal chemistry 20020401
Randomized trial of alcohol versus triple dye for umbilical cord care. Clinical pediatrics 20020101
[NMR study of complex formation of aromatic ligands with heptadeoxynucleotide 5'-d(GCGAAGC) forming stable hairpin structure in aqueous solution]. Molekuliarnaia biologiia 20020101
Dialysis cells for controlled DNA: drug binding studies. The Analyst 20010601
Contact dermatitis complicating pinnaplasty. British journal of plastic surgery 20010401
Proflavine-mediated inactivation of Salmonella dublin exposed to visible sunlight in natural fresh water. Microbios 20010101
Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity. Biochemistry 19940726
Kinetics of alpha-chymotrypsin dimerization. The Journal of biological chemistry 19760125
Properties