Home Other Building Blocks 1H-Benzotriazol-7-amine

1H-Benzotriazol-7-amine

CAS No.:
18076-61-4
Catalog Number:
AG0022C8
Molecular Formula:
C6H6N4
Molecular Weight:
134.1386
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Product Description
Catalog Number:
AG0022C8
Chemical Name:
1H-Benzotriazol-7-amine
CAS Number:
18076-61-4
Molecular Formula:
C6H6N4
Molecular Weight:
134.1386
MDL Number:
MFCD00962622
IUPAC Name:
2H-benzotriazol-4-amine
InChI:
InChI=1S/C6H6N4/c7-4-2-1-3-5-6(4)9-10-8-5/h1-3H,7H2,(H,8,9,10)
InChI Key:
ZDWPBMJZDNXTPG-UHFFFAOYSA-N
SMILES:
Nc1cccc2c1[nH]nn2
EC Number:
241-982-2
Properties
Complexity:
127  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
134.059g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
134.142g/mol
Monoisotopic Mass:
134.059g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
67.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.3  
Literature
Title Journal
Boosting of HIV protease inhibitors by ritonavir in the intestine: the relative role of cytochrome P450 and P-glycoprotein inhibition based on Caco-2 monolayers versus in situ intestinal perfusion in mice. Drug metabolism and disposition: the biological fate of chemicals 20120801
The genotoxic potential of methapyrilene using the alkaline Comet assay in vitro and in vivo. Toxicology 20111218
Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice. Archives of toxicology 20090701
Bioactivation of fluorotelomer alcohols in isolated rat hepatocytes. Chemico-biological interactions 20090212
Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse. Toxicological sciences : an official journal of the Society of Toxicology 20090201
Cadmium generates reactive oxygen- and carbon-centered radical species in rats: insights from in vivo spin-trapping studies. Free radical biology & medicine 20080815
Prostaglandins inhibit cytochrome P450 4A activity and contribute to endotoxin-induced hypotension in rats via nitric oxide production. Archives of pharmacal research 20080701
Saturable uptake of lipophilic amine drugs into isolated hepatocytes: mechanisms and consequences for quantitative clearance prediction. Drug metabolism and disposition: the biological fate of chemicals 20070801
Uptake and intracellular binding of lipophilic amine drugs by isolated rat hepatocytes and implications for prediction of in vivo metabolic clearance. Drug metabolism and disposition: the biological fate of chemicals 20061101
Inhibition by nitric oxide of cytochrome P450 4A activity contributes to endotoxin-induced hypotension in rats. Nitric oxide : biology and chemistry 20060201
Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatocytes. Chemico-biological interactions 20050815
The use of the suicide CYP450 inhibitor ABT for distinguishing absorption and metabolism processes in in-vivo pharmacokinetic screens. European journal of drug metabolism and pharmacokinetics 20050101
Contribution of renal oxygenases to glycerol-induced acute renal failure in the rat. Journal of cardiovascular pharmacology 20020601
Toxicity of a sevoflurane degradation product incubated with rat liver and renal cortical slices. Drug and chemical toxicology 20011101
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