Home Other Building Blocks 4-Pyridinamine, N-(1-ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-

4-Pyridinamine, N-(1-ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-

CAS No.:
175140-00-8
Catalog Number:
AG0020C4
Molecular Formula:
C21H30N2O
Molecular Weight:
326.4757
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$240
- +
10mg
99%
1 week
United States
$365
- +
25mg
99%
1 week
United States
$707
- +
50mg
99%
1 week
United States
$1290
- +
100mg
99%
1 week
United States
$2390
- +
Product Description
Catalog Number:
AG0020C4
Chemical Name:
4-Pyridinamine, N-(1-ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-
CAS Number:
175140-00-8
Molecular Formula:
C21H30N2O
Molecular Weight:
326.4757
MDL Number:
MFCD14584860
IUPAC Name:
3,6-dimethyl-N-pentan-3-yl-2-(2,4,6-trimethylphenoxy)pyridin-4-amine
InChI:
InChI=1S/C21H30N2O/c1-8-18(9-2)23-19-12-16(6)22-21(17(19)7)24-20-14(4)10-13(3)11-15(20)5/h10-12,18H,8-9H2,1-7H3,(H,22,23)
InChI Key:
VIZBSVDBNLAVAW-UHFFFAOYSA-N
SMILES:
CCC(Nc1cc(C)nc(c1C)Oc1c(C)cc(cc1C)C)CC
UNII:
5113G7FP34
Properties
Complexity:
359  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
326.236g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
326.484g/mol
Monoisotopic Mass:
326.236g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
34.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
6.4  
Literature
Title Journal
Dissociation of corticotropin-releasing factor receptor subtype involvement in sensitivity to locomotor effects of methamphetamine and cocaine. Psychopharmacology 20120201
Augmented cocaine seeking in response to stress or CRF delivered into the ventral tegmental area following long-access self-administration is mediated by CRF receptor type 1 but not CRF receptor type 2. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803
Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist. Journal of medicinal chemistry 20110623
Elevated corticosterone in the amygdala leads to persistent increases in anxiety-like behavior and pain sensitivity. Behavioural brain research 20101225
A comparison of ligand based virtual screening methods and application to corticotropin releasing factor 1 receptor. Journal of molecular graphics & modelling 20090101
2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists. Journal of medicinal chemistry 20080313
Properties