4-Amino-1,8-naphthalimide
| Title | Journal |
|---|---|
| The role of NF-κB in PARP-inhibitor-mediated sensitization and detoxification of arsenic trioxide in hepatocellular carcinoma cells. | The Journal of toxicological sciences 20150601 |
| PARP-1 inhibitor sensitizes arsenic trioxide in hepatocellular carcinoma cells via abrogation of G2/M checkpoint and suppression of DNA damage repair. | Chemico-biological interactions 20150125 |
| A new polymerizable fluorescent PET chemosensor of fluoride (F-) based on naphthalimide-thiourea dye. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120501 |
| Synthesis and photophysical evaluation of a pyridinium 4-amino-1,8-naphthalimide derivative that upon intercalation displays preference for AT-rich double-stranded DNA. | Organic & biomolecular chemistry 20120421 |
| The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation. | Cellular and molecular life sciences : CMLS 20120301 |
| [Effect of PARP-1 inhibitor 4-amino-1 ,8-naphthalimide on the on the sensitivity of adriamycin]. | Wei sheng yan jiu = Journal of hygiene research 20120301 |
| Small fragment homologous replacement: evaluation of factors influencing modification efficiency in an eukaryotic assay system. | PloS one 20120101 |
| OFF-ON-OFF fluorescence switch with T-latch function. | Organic letters 20111021 |
| XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage. | Environmental and molecular mutagenesis 20111001 |
| A naphthalimide fluorophore with efficient intramolecular PET and ICT processes: application in molecular logic. | Organic & biomolecular chemistry 20110807 |
| Luminescence targeting and imaging using a nanoscale generation 3 dendrimer in an in vivo colorectal metastatic rat model. | Nanomedicine : nanotechnology, biology, and medicine 20110601 |
| A highly selective colorimetric and ratiometric two-photon fluorescent probe for fluoride ion detection. | Organic letters 20110304 |
| Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition. | DNA repair 20110207 |
| Targeting poly(ADP-ribose) polymerase activity for cancer therapy. | Cellular and molecular life sciences : CMLS 20101101 |
| Delayed activation of caspase-independent apoptosis during heart failure in transgenic mice overexpressing caspase inhibitor CrmA. | American journal of physiology. Heart and circulatory physiology 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Colorimetric and fluorescent anion sensors: an overview of recent developments in the use of 1,8-naphthalimide-based chemosensors. | Chemical Society reviews 20101001 |
| Synthesis, photophysical, and DNA binding studies of fluorescent Tröger's base derived 4-amino-1,8-naphthalimide supramolecular clefts. | The Journal of organic chemistry 20100820 |
| Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks. | DNA repair 20100805 |
| Design and synthesis of a highly sensitive off-on fluorescent chemosensor for zinc ions utilizing internal charge transfer. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100111 |
| Concurrent targeting of nitrosative stress-PARP pathway corrects functional, behavioral and biochemical deficits in experimental diabetic neuropathy. | Biochemical and biophysical research communications 20100101 |
| Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. | PloS one 20100101 |
| Synthesis and characterization of environment-sensitive fluorescent ligands for human 5-HT1A receptors with 1-arylpiperazine structure. | Journal of medicinal chemistry 20091210 |
| PARP inhibition during alkylation-induced genotoxic stress signals a cell cycle checkpoint response mediated by ATM. | DNA repair 20091102 |
| DNA polymerase beta and PARP activities in base excision repair in living cells. | DNA repair 20091102 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| 4-Amino-1,8-naphthalimide-based Tröger's bases as high affinity DNA targeting fluorescent supramolecular scaffolds. | Organic letters 20090917 |
| Demonstration of bidirectional photoinduced electron transfer (PET) sensing in 4-amino-1,8-naphthalimide based thiourea anion sensors. | Organic & biomolecular chemistry 20090907 |
| Unexpected fluorescent behavior of a 4-amino-1,8-naphthalimide derived beta-cyclodextrin: conformation analysis and sensing properties. | Chemical communications (Cambridge, England) 20090721 |
| Neuroprotective potential of combination of resveratrol and 4-amino 1,8 naphthalimide in experimental diabetic neuropathy: focus on functional, sensorimotor and biochemical changes. | Free radical research 20090401 |
| Induction of apoptosis by the inhibitors of poly(ADP-ribose)polymerase in HeLa cells. | Molecular and cellular biochemistry 20090101 |
| PARP-1 is involved in autophagy induced by DNA damage. | Autophagy 20090101 |
| Protective effects of 4-amino1,8-napthalimide, a poly (ADP-ribose) polymerase inhibitor in experimental diabetic neuropathy. | Life sciences 20080312 |
| Highly effective DNA photocleavage by novel 'rigid' Ru(bpy)(3)-4-nitro- and -4-amino-1,8-naphthalimide conjugates. | Inorganic chemistry 20080121 |
| Synthesis, evaluation, and computational studies of naphthalimide-based long-wavelength fluorescent boronic Acid reporters. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity. | DNA repair 20070601 |
| Highly selective 4-amino-1,8-naphthalimide based fluorescent photoinduced electron transfer (PET) chemosensors for Zn(II) under physiological pH conditions. | Organic & biomolecular chemistry 20070121 |
| Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition. | BMC molecular biology 20070101 |
| A stronger DNA damage-induced G2 checkpoint due to over-activated CHK1 in the absence of PARP-1. | Cell cycle (Georgetown, Tex.) 20061001 |
| Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis. | Molecular cancer therapeutics 20060301 |
| Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair. | Nucleic acids research 20060101 |
| Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death. | DNA repair 20050928 |
| Benzamide and 4-amino 1,8 naphthalimide treatment inhibit telomerase activity by down-regulating the expression of telomerase associated protein and inhibiting the poly(ADP-ribosyl)ation of telomerase reverse transcriptase in cultured cells. | The FEBS journal 20050801 |
| Cerebral endothelial cell apoptosis after ischemia-reperfusion: role of PARP activation and AIF translocation. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050701 |
| Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure. | The Journal of biological chemistry 20050422 |
| PARP inhibition sensitizes p53-deficient breast cancer cells to doxorubicin-induced apoptosis. | The Biochemical journal 20050215 |
| Fluorescence sensor design for transition metal ions: the role of the PIET interaction efficiency. | Journal of fluorescence 20050101 |
| Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase. | Journal of medicinal chemistry 20041021 |
| An enzymatic assay for poly(ADP-ribose) polymerase-1 (PARP-1) via the chemical quantitation of NAD(+): application to the high-throughput screening of small molecules as potential inhibitors. | Analytical biochemistry 20040301 |
| Neuroprotective effect of 4-amino-1,8-napthalimide, a poly(ADP ribose) polymerase inhibitor in middle cerebral artery occlusion-induced focal cerebral ischemia in rat. | Brain research bulletin 20040201 |
| Toward the elucidation of the catalytic mechanism of the mono-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exotoxin A. | Biochemistry 20040113 |
| Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects. | European journal of medical research 20031022 |
| Using spin dynamics of covalently linked radical ion pairs to probe the impact of structural and energetic changes on charge recombination. | Journal of the American Chemical Society 20030528 |
| The effect of poly (adenosine diphosphate-ribose) polymerase inhibitors on biochemical changes in testicular ischemia-reperfusion injury. | The Journal of urology 20030501 |
| A fluorescent sensor with high selectivity and sensitivity for potassium in water. | Journal of the American Chemical Society 20030212 |
| Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery. | BMC cell biology 20030101 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Covalently immobilized aminonaphthalimide as fluorescent carrier for the preparation of optical sensors. | Analytical and bioanalytical chemistry 20020201 |
| Role of zinc in pulmonary endothelial cell response to oxidative stress. | American journal of physiology. Lung cellular and molecular physiology 20010701 |