Home Aldehydes Chromone-3-carboxaldehyde

Chromone-3-carboxaldehyde

CAS No.:
17422-74-1
Catalog Number:
AG001ZID
Molecular Formula:
C10H6O3
Molecular Weight:
174.1528
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$19
- +
25g
98%
In Stock USA
United States
$75
- +
100g
98%
In Stock USA
United States
$250
- +
Product Description
Catalog Number:
AG001ZID
Chemical Name:
Chromone-3-carboxaldehyde
CAS Number:
17422-74-1
Molecular Formula:
C10H6O3
Molecular Weight:
174.1528
MDL Number:
MFCD00014667
IUPAC Name:
4-oxochromene-3-carbaldehyde
InChI:
InChI=1S/C10H6O3/c11-5-7-6-13-9-4-2-1-3-8(9)10(7)12/h1-6H
InChI Key:
FSMYWBQIMDSGQP-UHFFFAOYSA-N
SMILES:
O=Cc1coc2c(c1=O)cccc2
EC Number:
241-451-5
NSC Number:
291317
Properties
Complexity:
267  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
174.032g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
174.155g/mol
Monoisotopic Mass:
174.032g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
43.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.2  
Literature
Title Journal
Chromone containing sulfonamides as potent carbonic anhydrase inhibitors. Journal of enzyme inhibition and medicinal chemistry 20121001
Selected chromone derivatives as inhibitors of monoamine oxidase. Bioorganic & medicinal chemistry letters 20120901
Thermal solvent-free synthesis of chromonyl chalcones, pyrazolines and their in vitro antibacterial, antifungal activities. Journal of enzyme inhibition and medicinal chemistry 20120201
3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells. The Journal of biological chemistry 20120102
Synthesis of furo[3,2-b]pyrrole-5-carboxhydrazides and their Cu, Co and Ni complexes. TheScientificWorldJournal 20120101
Physiochemical, optical and biological activity of chitosan-chromone derivative for biomedical applications. International journal of molecular sciences 20120101
Synthesis, characterization and biological activity of some new VO(IV), Co(II), Ni(II), Cu(II) and Zn(II) complexes of chromone based NNO Schiff base derived from 2-aminothiazole. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111101
4-Hy-droxy-3-[(4-hy-droxy-6,7-dimethyl-2-oxo-2H-chromen-3-yl)(4-oxo-4H-chromen-3-yl)meth-yl]-6,7-dimethyl-2H-chromen-2-one. Acta crystallographica. Section E, Structure reports online 20101101
3-Formylchromones: potential antiinflammatory agents. European journal of medicinal chemistry 20100901
Discovery of novel antitubercular 2,10-dihydro-4aH-chromeno[3,2-c]pyridin-3-yl derivatives. European journal of medicinal chemistry 20100101
Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors. Bioorganic & medicinal chemistry 20090415
Synthesis of quinolines from 3-formylchromone. The Journal of organic chemistry 20080801
Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. Natural product reports 20080801
Relationship between structure and antioxidative properties of some 3-formylchromone derivatives. Medicinal chemistry (Shariqah (United Arab Emirates)) 20080701
Quantitative structure-cytotoxicity relationship analysis of 3-formylchromone derivatives by a semiempirical molecular-orbital method with the concept of absolute hardness. Anticancer research 20080101
Synthesis and Pharmacological Evaluation of (6-Substituted 4-Oxo-4H-chromene-3 yl) methyl N-substituted Aminoacetates. Indian journal of pharmaceutical sciences 20080101
Synthesis and antidiabetic activity of some new chromonyl-2,4-thiazolidinediones. Arzneimittel-Forschung 20070101
Biological activity of 3-formylchromones and related compounds. In vivo (Athens, Greece) 20070101
In vivo antitumor, in vitro antibacterial activity and alkylating properties of phosphorohydrazine derivatives of coumarin and chromone. European journal of medicinal chemistry 20061101
Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells. Journal of medicinal chemistry 20060629
Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells. In vivo (Athens, Greece) 20060101
3-Formylchromones IV. The rearrangement of 3-formylchromone enamines as a simple, facile route to novel pyrazolo[3,4-b]pyridines and the synthetic utility of the latter. Molecules (Basel, Switzerland) 20050831
Reactions of 3-formylchromone with active methylene and methyl compounds and some subsequent reactions of the resulting condensation products. Molecules (Basel, Switzerland) 20050831
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes. Bioorganic & medicinal chemistry letters 20050615
Induction of apoptosis by beta-diketones in human tumor cells. Anticancer research 20040101
Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors. Bioorganic & medicinal chemistry letters 20030804
Properties