sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks Y-33075 dihydrochloride

Y-33075 dihydrochloride

CAS No.:
173897-44-4
Catalog Number:
AG001Z9V
Molecular Formula:
C16H18Cl2N4O
Molecular Weight:
353.2463
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
97%
1 week
United States
$257
- +
10mg
97%
1 week
United States
$390
- +
50mg
97%
1 week
United States
$1390
- +
100mg
97%
1 week
United States
$2223
- +
Product Description
Catalog Number:
AG001Z9V
Chemical Name:
Y-33075 dihydrochloride
CAS Number:
173897-44-4
Molecular Formula:
C16H18Cl2N4O
Molecular Weight:
353.2463
MDL Number:
MFCD16038860
IUPAC Name:
4-[(1R)-1-aminoethyl]-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide;dihydrochloride
InChI:
InChI=1S/C16H16N4O.2ClH/c1-10(17)11-2-4-12(5-3-11)16(21)20-14-7-9-19-15-13(14)6-8-18-15;;/h2-10H,17H2,1H3,(H2,18,19,20,21);2*1H/t10-;;/m1../s1
InChI Key:
CKFHAVRPVZNMGT-YQFADDPSSA-N
SMILES:
O=C(c1ccc(cc1)[C@H](N)C)Nc1ccnc2c1cc[nH]2.Cl.Cl
Properties
Complexity:
367  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
352.086g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
353.247g/mol
Monoisotopic Mass:
352.086g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
83.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Effects of Y-39983, a selective Rho-associated protein kinase inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats. Current eye research 20111001
Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries. Japanese journal of ophthalmology 20110701
Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells. Molecular vision 20110101
Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090601
[Optic nerve regeneration in adult mammals]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20080601
A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats. Experimental neurology 20070501
Properties