Lixivaptan
Title | Journal |
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[Hyponatremic hypervolemia in heart failure--the hot spot for vasopressin receptor antagonists?]. | Wiadomosci lekarskie (Warsaw, Poland : 1960) 20120101 |
Targeting hyponatremia and hemodynamics in acute decompensated heart failure: is there a role for vasopressin antagonists? | Current heart failure reports 20110901 |
The potential role for lixivaptan in heart failure and in hyponatremia. | Expert opinion on investigational drugs 20110601 |
Arginine vasopressin (AVP) and treatment with arginine vasopressin receptor antagonists (vaptans) in congestive heart failure, liver cirrhosis and syndrome of inappropriate antidiuretic hormone secretion (SIADH). | European journal of clinical pharmacology 20110401 |
Lixivaptan, a non-peptide vasopressin V2 receptor antagonist for the potential oral treatment of hyponatremia. | IDrugs : the investigational drugs journal 20101101 |
Rationale and design of the treatment of hyponatremia based on lixivaptan in NYHA class III/IV cardiac patient evaluation (THE BALANCE) study. | Clinical and translational science 20101001 |
Vasopressin receptor antagonists for the treatment of hyponatremia: systematic review and meta-analysis. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20100801 |
The critical link of hypervolemia and hyponatremia in heart failure and the potential role of arginine vasopressin antagonists. | Journal of cardiac failure 20100501 |
[Hyponatremia in heart failure: physiopathology and pharmacological approach]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20100501 |
[Vasopressin receptor antagonists: the vaptans]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20100501 |
Vasopressin antagonists: Pharmacotherapy for the treatment of heart failure. | The Annals of pharmacotherapy 20100401 |
[Vasopressin receptor antagonists and heart failure]. | Therapeutische Umschau. Revue therapeutique 20091101 |
Pharmacology of vasopressin antagonists. | Heart failure reviews 20090601 |
AVP receptor antagonists in patients with CHF. | Heart failure reviews 20090601 |
Treatment options for hyponatremia in heart failure. | Heart failure reviews 20090601 |
Lixivaptan: a novel vasopressin receptor antagonist. | Expert opinion on investigational drugs 20090501 |
[Etiology, diagnostics and therapy of hyponatremias]. | Orvosi hetilap 20080720 |
Vasopressin and vasopressin antagonists in heart failure and hyponatremia. | Current heart failure reports 20080601 |
Vasopressin-receptor antagonists in heart failure. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080501 |
Hyponatremia and vasopressin antagonism in congestive heart failure. | Clinical cardiology 20071101 |
Identification and synthesis of major metabolites of Vasopressin V2-receptor agonist WAY-151932, and antagonist, Lixivaptan. | Bioorganic & medicinal chemistry letters 20071101 |
Current issues for nurse practitioners: Hyponatremia. | Journal of the American Academy of Nurse Practitioners 20071101 |
Recognition and treatment of hyponatremia in acutely ill hospitalized patients. | Clinical therapeutics 20070201 |
[Arginine vasopressin antagonism--new treatment option in chronic heart failure]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20070118 |
Therapeutic potential of vasopressin receptor antagonists. | Drugs 20070101 |
AVP receptor antagonists as aquaretics: review and assessment of clinical data. | Cleveland Clinic journal of medicine 20060901 |
Vasopressin antagonists. | Cellular and molecular life sciences : CMLS 20060801 |
Vasopressin antagonists as aquaretic agents for the treatment of hyponatremia. | The American journal of medicine 20060701 |
Vasopressin receptor antagonists. | Kidney international 20060601 |
Vasopressin receptor antagonists in heart failure. | Recent patents on cardiovascular drug discovery 20060601 |
Vasopressin excess and hyponatremia. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20060501 |
(4-Substituted-phenyl)-(5H-10,11-dihydro-pyrrolo [2,1-c][1,4] benzodiazepin-10-yl)-methanone derivatives as vasopressin receptor modulators. | Bioorganic & medicinal chemistry letters 20051115 |
Role of vasopressin antagonists in the management of acute decompensated heart failure. | Current heart failure reports 20050901 |
Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates. | Bioorganic & medicinal chemistry letters 20040607 |
Vasopressin receptor antagonists in heart failure. | Current opinion in pharmacology 20031201 |
2,5-disubstituted 3,4-dihydro-2H-benzo[b][1,4]thiazepines as potent and selective V2 arginine vasopressin receptor antagonists. | Bioorganic & medicinal chemistry letters 20031117 |
Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists. | Bioorganic & medicinal chemistry letters 20030707 |
Therapeutic role of vasopressin receptor antagonism in patients with liver cirrhosis. | Clinical science (London, England : 1979) 20030701 |
Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist: a randomized double-blind multicenter trial. | Gastroenterology 20030401 |
A vasopressin receptor antagonist (VPA-985) improves serum sodium concentration in patients with hyponatremia: a multicenter, randomized, placebo-controlled trial. | Hepatology (Baltimore, Md.) 20030101 |
Bridged bicyclic vasopressin receptor antagonists with V(2)-selective or dual V(1a)/V(2) activity. | Bioorganic & medicinal chemistry letters 20021104 |
Pharmacodynamic effects of a nonpeptide antidiuretic hormone V2 antagonist in cirrhotic patients with ascites. | Hepatology (Baltimore, Md.) 20021101 |
Treatment of hyponatremic encephalopathy. | The Journal of laboratory and clinical medicine 20011201 |
Treatment of hyponatremic encephalopathy with antagonists to antidiuretic hormone. | The Journal of laboratory and clinical medicine 20010701 |
Difference in solute excretion during correction of hyponatremic patients with cirrhosis or syndrome of inappropriate secretion of antidiuretic hormone by oral vasopressin V2 receptor antagonist VPA-985. | The Journal of laboratory and clinical medicine 20010701 |
Lixivaptan (American Home Products). | Current opinion in investigational drugs (London, England : 2000) 20010401 |
5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c]-[1, 4]benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl]benzamide (VPA-985): an orally active arginine vasopressin antagonist with selectivity for V2 receptors. | Journal of medicinal chemistry 19980702 |