Diphenyl diselenide supplementation reduces biochemical alterations associated with oxidative stress in rats fed with fructose and hydrochlorothiazide.

Chemico-biological interactions 20130825

Organoselenium compounds modulate extracellular redox by induction of extracellular cysteine and cell surface thioredoxin reductase.

Chemical research in toxicology 20130318

Mitochondrial electron transfer chain complexes inhibition by different organochalcogens.

Toxicology in vitro : an international journal published in association with BIBRA 20130201

Effects of diphenyl diselenide on methylmercury toxicity in rats.

BioMed research international 20130101

Antioxidant properties of diorganoyl diselenides and ditellurides: modulation by organic aryl or naphthyl moiety.

Molecular and cellular biochemistry 20121201

Interaction profile of diphenyl diselenide with pharmacologically significant thiols.

Molecules (Basel, Switzerland) 20121019

Diphenyl diselenide reduces inflammation in the mouse model of pleurisy induced by carrageenan: reduction of pro-inflammatory markers and reactive species levels.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20121001

Protective effect of diphenyl diselenide on ischemia and reperfusion-induced cerebral injury: involvement of oxidative stress and pro-inflammatory cytokines.

Neurochemical research 20121001

Diphenyl diselenide attenuates hepatic and hematologic toxicity induced by chlorpyrifos acute exposure in rats.

Environmental science and pollution research international 20120901

Cooperation of non-effective concentration of glutamatergic system modulators and antioxidant against oxidative stress induced by quinolinic acid.

Neurochemical research 20120901

Diphenyl diselenide ameliorates behavioral and oxidative parameters in an animal model of mania induced by ouabain.

Progress in neuro-psychopharmacology & biological psychiatry 20120807

Diphenyl diselenide-modulation of macrophage activation: down-regulation of classical and alternative activation markers.

Innate immunity 20120801

Effects of diphenyl diselenide on depressive-like behavior in ovariectomized mice submitted to subchronic stress: involvement of the serotonergic system.

Psychopharmacology 20120801

The effects of diphenyl diselenide on oxidative stress biomarkers in Cyprinus carpio exposed to herbicide quinclorac (Facet®).

Ecotoxicology and environmental safety 20120701

Reduction of acute hepatic damage induced by acetaminophen after treatment with diphenyl diselenide in mice.

Toxicologic pathology 20120601

Diphenyl diselenide in vitro and in vivo activity against the oomycete Pythium insidiosum.

Veterinary microbiology 20120423

Acute brain damage induced by acetaminophen in mice: effect of diphenyl diselenide on oxidative stress and mitochondrial dysfunction.

Neurotoxicity research 20120401

Diphenyl diselenide diet intake improves spatial learning and memory deficits in hypothyroid female rats.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20120401

Diphenyl diselenide ameliorates cognitive deficits induced by a model of menopause in rats.

Behavioural pharmacology 20120201

Methylselenocysteine treatment leads to diselenide formation in human cancer cells: evidence from X-ray absorption spectroscopy studies.

Biochemistry 20120124

The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains.

Brain research 20120109

Fe(II) and sodium nitroprusside induce oxidative stress: a comparative study of diphenyl diselenide and diphenyl ditelluride with their napthyl analog.

Drug and chemical toxicology 20120101

Effect of diphenyl diselenide on the development of experimental autoimmune encephalomyelitis.

Neurochemistry international 20111201

Candida albicans growth and germ tube formation can be inhibited by simple diphenyl diselenides [(PhSe)2, (MeOPhSe)2, (p-Cl-PhSe)2, (F3CPhSe)2] and diphenyl ditelluride.

Mycoses 20111101

Diphenyl diselenide potentiates nephrotoxicity induced by mercuric chloride in mice.

Journal of applied toxicology : JAT 20111101

Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20111101

Diphenyl diselenide and analogs are substrates of cerebral rat thioredoxin reductase: a pathway for their neuroprotective effects.

Neuroscience letters 20110926

Effects of diphenyl diselenide on oxidative stress induced by sepsis in rats.

Pathology, research and practice 20110915

In vitro antifungal evaluation and structure-activity relationship of diphenyl diselenide and synthetic analogues.

Mycoses 20110901

The role of the glutathione system in seizures induced by diphenyl diselenide in rat pups.

Chemico-biological interactions 20110815

Diphenyl diselenide effectively reduces atherosclerotic lesions in LDLr -/- mice by attenuation of oxidative stress and inflammation.

Journal of cardiovascular pharmacology 20110701

Diphenyl diselenide induces apoptotic cell death and modulates ERK1/2 phosphorylation in human neuroblastoma SH-SY5Y cells.

Archives of toxicology 20110601

Diphenyl diselenide induces anxiolytic-like and sedative effects on the chick social separation-stress behavior.

Neuroscience letters 20110516

Effects of diphenyl diselenide on lipid profile and hepatic oxidative stress parameters in ovariectomized female rats.

The Journal of pharmacy and pharmacology 20110501

Neuroprotector effect of p,p'-methoxyl-diphenyl diselenide in a model of sporadic dementia of Alzheimer's type in mice: contribution of antioxidant mechanism.

Cell biochemistry and function 20110401

Inhibitory effect of ebselen on lactate dehydrogenase activity from mammals: a comparative study with diphenyl diselenide and diphenyl ditelluride.

Drug and chemical toxicology 20110101

Diphenyl diselenide-induced seizures in rat pups: possible interaction with GABAergic system.

Neurological research 20101101

Acute exposure of rabbits to diphenyl diselenide: a toxicological evaluation.

Journal of applied toxicology : JAT 20101101

Reduction of diphenyl diselenide and analogs by mammalian thioredoxin reductase is independent of their gluthathione peroxidase-like activity: a possible novel pathway for their antioxidant activity.

Molecules (Basel, Switzerland) 20101028

Comparative study on the influence of subcutaneous administration of diphenyl and dicholesteroyl diselenides on sulphydryl proteins and antioxidant parameters in mice.

Journal of applied toxicology : JAT 20101001

Association between diphenyl diselenide and cadmium chloride attenuates the toxicity of both in tissues of mice in vitro.

Toxicology in vitro : an international journal published in association with BIBRA 20100901

Diphenyl diselenide improves scopolamine-induced memory impairment in mice.

Behavioural pharmacology 20100901

Evidence of the involvement of K+ channels and PPARgamma receptors in the antidepressant-like activity of diphenyl diselenide in mice.

The Journal of pharmacy and pharmacology 20100901

Diphenyl diselenide in its selenol form has dehydroascorbate reductase and glutathione S-transferase-like activity dependent on the glutathione content.

The Journal of pharmacy and pharmacology 20100901

Diphenyl diselenide and diphenyl ditelluride: neurotoxic effect in brain of young rats, in vitro.

Molecular and cellular biochemistry 20100701

Diphenyl diselenide behaves differently than ebselen under different pH media in rat's liver preparations.

Pathology, research and practice 20100615

Convulsant action of diphenyl diselenide in rat pups: measurement and correlation with plasma, liver and brain levels of compound.

Archives of toxicology 20100501

Reduction of hydrogen peroxide by glutathione peroxidase mimics: reaction mechanism and energetics.

The journal of physical chemistry. A 20100204

Acute treatment with diphenyl diselenide inhibits glutamate uptake into rat hippocampal slices and modifies glutamate transporters, SNAP-25, and GFAP immunocontent.

Toxicological sciences : an official journal of the Society of Toxicology 20100201

Altered pH homeostasis modulates the glutathione peroxidase mimics and other antioxidant properties of diphenyl diselenide.

Chemico-biological interactions 20091210

Disubstituted diaryl diselenides inhibit delta-ALA-D and Na+, K+-ATPase activities in rat brain homogenates in vitro.

Molecular and cellular biochemistry 20091201

Hypolipidaemic activity of orally administered diphenyl diselenide in Triton WR-1339-induced hyperlipidaemia in mice.

The Journal of pharmacy and pharmacology 20091201

Towards the mechanism and comparative effect of diphenyl diselenide, diphenyl ditelluride and ebselen under various pathophysiological conditions in rat's kidney preparation.

Chemico-biological interactions 20091110

PdCl2-promoted electrophilic annulation of 2-alkynylphenol derivatives with disulfides or diselenides in the presence of iodine.

The Journal of organic chemistry 20091016

Diphenyl diselenide protects against glycerol-induced renal damage in rats.

Journal of applied toxicology : JAT 20091001

Cesium carbonate-catalyzed alpha-phenylchalcogenation of carbonyl compounds with diphenyl dichalcogenide.

Molecules (Basel, Switzerland) 20090902

Convulsant effect of diphenyl diselenide in rats and mice and its relationship to plasma levels.

Toxicology letters 20090825

Diphenyl diselenide and streptozotocin did not alter cerebral glutamatergic and cholinergic systems but modulate antioxidant status and sodium pump in diabetic rats.

Brain research 20090811

Effect of oral administration of diphenyl diselenide on antioxidant status, and activity of delta aminolevulinic acid dehydratase and isoforms of lactate dehydrogenase, in streptozotocin-induced diabetic rats.

Cell biology and toxicology 20090801

Passive smoke exposure induces oxidative damage in brains of rat pups: Protective role of diphenyl diselenide.

Inhalation toxicology 20090801

Concomitant administration of sodium 2,3-dimercapto-1-propanesulphonate (DMPS) and diphenyl diselenide reduces effectiveness of DMPS in restoring damage induced by mercuric chloride in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801

Diphenyl diselenide decreases serum levels of total cholesterol and tissue oxidative stress in cholesterol-fed rabbits.

Basic & clinical pharmacology & toxicology 20090701

Chronic treatment with fluphenazine alters parameters of oxidative stress in liver and kidney of rats.

Basic & clinical pharmacology & toxicology 20090701

Antioxidant effect of diphenyl diselenide on oxidative stress caused by acute physical exercise in skeletal muscle and lungs of mice.

Cell biochemistry and function 20090601

Genotoxicity of organoselenium compounds in human leukocytes in vitro.

Mutation research 20090531

Antidepressant-like effect of diphenyl diselenide on rats exposed to malathion: involvement of Na+K+ ATPase activity.

Neuroscience letters 20090522

Introduction of trifluoromethyl group into diphenyl diselenide molecule alters its toxicity and protective effect against damage induced by 2-nitropropane in rats.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20090501

Diphenyldiselenide-catalyzed selective oxidation of activated alcohols with tert-butyl hydroperoxide: new mechanistic insights.

The Journal of organic chemistry 20090417

Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice.

Brain research bulletin 20090406

Enhancement of iron-catalyzed lipid peroxidation by acidosis in brain homogenate: comparative effect of diphenyl diselenide and ebselen.

Brain research 20090303

Oral administration of diphenyl diselenide potentiates hepatotoxicity induced by carbon tetrachloride in rats.

Journal of applied toxicology : JAT 20090301

Brain and lungs of rats are differently affected by cigarette smoke exposure: antioxidant effect of an organoselenium compound.

Pharmacological research 20090301

Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system.

Toxicology in vitro : an international journal published in association with BIBRA 20090301

Studies on the antioxidant effect and interaction of diphenyl diselenide and dicholesteroyl diselenide with hepatic delta-aminolevulinic acid dehydratase and isoforms of lactate dehydrogenase.

Toxicology in vitro : an international journal published in association with BIBRA 20090201

Human erythrocyte hemolysis induced by selenium and tellurium compounds increased by GSH or glucose: a possible involvement of reactive oxygen species.

Chemico-biological interactions 20090115

Antioxidant effect of diphenyl diselenide on oxidative damage induced by smoke in rats: involvement of glutathione.

Ecotoxicology and environmental safety 20090101

Diphenyl diselenide and diphenyl ditelluride increase the latency for 4-aminopyridine-induced chemical seizure and prevent death in mice.

Acta biochimica Polonica 20090101

Disubstituted diaryl diselenides inhibit [3H]-serotonin uptake in rats.

Neurotoxicity research 20090101

Involvement of non-enzymatic antioxidant defenses in the protective effect of diphenyl diselenide on testicular damage induced by cadmium in mice.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20090101

m-Trifluoromethyl-diphenyl diselenide attenuates pentylenetetrazole-induced seizures in mice by inhibiting GABA uptake in cerebral cortex slices.

Pharmacological reports : PR 20090101

Mechanisms involved in the antinociceptive effect caused by diphenyl diselenide in the formalin test.

The Journal of pharmacy and pharmacology 20081201

Acute diphenyl diselenide treatment reduces hyperglycemia but does not change delta-aminolevulinate dehydratase activity in alloxan-induced diabetes in rats.

Biological & pharmaceutical bulletin 20081201

Diphenyl diselenide, a simple glutathione peroxidase mimetic, inhibits human LDL oxidation in vitro.

Atherosclerosis 20081101

Diphenyl diselenide supplementation delays the development of N-nitroso-N-methylurea-induced mammary tumors.

Archives of toxicology 20080901

Diphenyl diselenide reverses gastric lesions in rats: Involvement of oxidative stress.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901

Diphenyl diselenide exerts anxiolytic-like effect in Wistar rats: putative roles of GABAA and 5HT receptors.

Progress in neuro-psychopharmacology & biological psychiatry 20080801

Toxicological evaluation of subchronic exposure to diphenyl diselenide in rats.

Journal of applied toxicology : JAT 20080701

Diphenyl diselenide-induced seizures in rat pups: possible interaction with glutamatergic system.

Neurochemical research 20080601

Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.

Neuroscience letters 20080509

Sub-chronical exposure to diphenyl diselenide enhances acquisition and retention of spatial memory in rats.

Brain research 20080327

Diphenyl diselenide confers neuroprotection against hydrogen peroxide toxicity in hippocampal slices.

Brain research 20080314

Diphenyl diselenide [(PhSe)2] inhibits Drosophila melanogaster delta-aminolevulinate dehydratase (delta-ALA-D) gene transcription and enzyme activity.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080301

Diphenyl diselenide exerts antidepressant-like and anxiolytic-like effects in mice: involvement of L-arginine-nitric oxide-soluble guanylate cyclase pathway in its antidepressant-like action.

Pharmacology, biochemistry, and behavior 20080201

Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats.

Chemico-biological interactions 20080110

Dietary diphenyl diselenide reduces the STZ-induced toxicity.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080101

Diphenyl diselenide protects against hematological and immunological alterations induced by mercury in mice.

Journal of biochemical and molecular toxicology 20080101

Diphenyl diselenide attenuates acute thermal hyperalgesia and persistent inflammatory and neuropathic pain behavior in mice.

Brain research 20071017

Diphenyl diselenide decreases the prevalence of vacuous chewing movements induced by fluphenazine in rats.

Psychopharmacology 20071001

(45)Ca(2+) influx in rat brain: effect of diorganylchalcogenides compounds.

Toxicological sciences : an official journal of the Society of Toxicology 20071001

Pharmacology and toxicology of diphenyl diselenide in several biological models.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20071001

Efficacy of diphenyl diselenide against cerebral and pulmonary damage induced by cadmium in mice.

Toxicology letters 20070928

DNA damage in tissues and organs of mice treated with diphenyl diselenide.

Mutation research 20070901

Monoaminergic agents modulate antidepressant-like effect caused by diphenyl diselenide in rats.

Progress in neuro-psychopharmacology & biological psychiatry 20070815

Spinal mechanisms of antinociceptive action caused by diphenyl diselenide.

Brain research 20070808

Antioxidant activity of diphenyl diselenide prevents the genotoxicity of several mutagens in Chinese hamster V79 cells.

Mutation research 20070710

Low toxicity of diphenyl diselenide in rabbits: a long-term study.

Basic & clinical pharmacology & toxicology 20070701

Ebselen and diorganylchalcogenides decrease in vitro glutamate uptake by rat brain slices: prevention by DTT and GSH.

Toxicology in vitro : an international journal published in association with BIBRA 20070601

Involvement of oxidative stress in seizures induced by diphenyl diselenide in rat pups.

Brain research 20070525

Cytotoxic, genotoxic, and mutagenic effects of diphenyl diselenide in Chinese hamster lung fibroblasts.

Mutation research 20070402

Diphenyl diselenide prevents oxidative damage induced by cigarette smoke exposure in lung of rat pups.

Toxicology 20070212

Repeated administration of diphenyl diselenide to pregnant rats induces adverse effects on embryonic/fetal development.

Reproductive toxicology (Elmsford, N.Y.) 20070201

Cadmium inhibits delta-aminolevulinate dehydratase from rat lung in vitro: interaction with chelating and antioxidant agents.

Chemico-biological interactions 20070130

Oxalate modulates thiobarbituric acid reactive species (TBARS) production in supernatants of homogenates from rat brain, liver and kidney: effect of diphenyl diselenide and diphenyl ditelluride.

Chemico-biological interactions 20070130

Antinociceptive properties of diphenyl diselenide: evidences for the mechanism of action.

European journal of pharmacology 20070126

Adult male rats sub-chronically exposed to diphenyl diselenide: Effects on their progeny.

Reproductive toxicology (Elmsford, N.Y.) 20070101

Antioxidant effect of diphenyl diselenide against sodium nitroprusside (SNP) induced lipid peroxidation in human platelets and erythrocyte membranes: an in vitro evaluation.

Chemico-biological interactions 20061201

Diphenyl diselenide reduces temporarily hyperglycemia: possible relationship with oxidative stress.

Chemico-biological interactions 20061107

Antioxidants and metallothionein levels in mercury-treated mice.

Cell biology and toxicology 20061101

Sub-chronic administration of diphenyl diselenide potentiates cadmium-induced testicular damage in mice.

Reproductive toxicology (Elmsford, N.Y.) 20061001

DMPS and N-acetylcysteine induced renal toxicity in mice exposed to mercury.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20060801

Changes in biochemical parameters in rabbits blood after oral exposure to diphenyl diselenide for long periods.

Chemico-biological interactions 20060725

Effects of diphenyl-diselenide on orofacial dyskinesia model in rats.

Brain research bulletin 20060630

Assessment of reproductive toxicity in male rats following acute and sub-chronic exposures to diphenyl diselenide and diphenyl ditelluride.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060501

Diphenyl ditelluride- and methylmercury-induced hyperphosphorilation of the high molecular weight neurofilament subunit is prevented by organoselenium compounds in cerebral cortex of young rats.

Toxicology 20060501

Effects of ethanol and diphenyl diselenide exposure on the activity of delta-aminolevulinate dehydratase from mouse liver and brain.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060401

Acute liver damage induced by 2-nitropropane in rats: effect of diphenyl diselenide on antioxidant defenses.

Chemico-biological interactions 20060325

Diphenyl diselenide and 2,3-dimercaptopropanol increase the PTZ-induced chemical seizure and mortality in mice.

Brain research bulletin 20060215

Diphenyl diselenide changes behavior in female pups.

Neurotoxicology and teratology 20060101

Efficacy of 2,3-dimercapto-1-propanesulfonic acid (DMPS) and diphenyl diselenide on cadmium induced testicular damage in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20051201

Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na(+), K(+)-ATPase activity in rats.

Toxicology 20051115

Ebselen protects glutamate uptake inhibition caused by methyl mercury but does not by Hg2+.

Toxicology 20051015

Pro-oxidant action of diphenyl diselenide in the yeast Saccharomyces cerevisiae exposed to ROS-generating conditions.

Life sciences 20050923

Organoselenium compounds prevent hyperphosphorylation of cytoskeletal proteins induced by the neurotoxic agent diphenyl ditelluride in cerebral cortex of young rats.

Toxicology 20050601

Protective effect of diphenyl diselenide on acute liver damage induced by 2-nitropropane in rats.

Toxicology 20050515

Selenium compounds prevent the effects of methylmercury on the in vitro phosphorylation of cytoskeletal proteins in cerebral cortex of young rats.

Toxicological sciences : an official journal of the Society of Toxicology 20050501

Effect of ebselen and organochalcogenides on excitotoxicity induced by glutamate in isolated chick retina.

Brain research 20050328

Diphenyl diselenide reverses cadmium-induced oxidative damage on mice tissues.

Chemico-biological interactions 20050210

Mechanism of delta-aminolevulinate dehydratase inhibition by phenyl selenoacetylene involves its conversion to diphenyl diselenide.

Toxicology 20050131

Teratogenic effects of diphenyl diselenide in Wistar rats.

Reproductive toxicology (Elmsford, N.Y.) 20050101

Aryl thiol substrate 3-carboxy-4-nitrobenzenethiol strongly stimulating thiol peroxidase activity of glutathione peroxidase mimic 2, 2'-ditellurobis(2-deoxy-beta-cyclodextrin).

Journal of the American Chemical Society 20041222

Effects of age on reserpine-induced orofacial dyskinesia and possible protection of diphenyl diselenide.

Brain research bulletin 20041215

Genotoxicity of diphenyl diselenide in bacteria and yeast.

Mutation research 20041010

Cadmium induced testicular damage and its response to administration of succimer and diphenyl diselenide in mice.

Toxicology letters 20040925

Diphenyl diselenide protects rat hippocampal slices submitted to oxygen-glucose deprivation and diminishes inducible nitric oxide synthase immunocontent.

Brain research 20031003

Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice.

Toxicology letters 20030605

Facilitation of long-term object recognition memory by pretraining administration of diphenyl diselenide in mice.

Neuroscience letters 20030508

Comparative deposition of diphenyl diselenide in liver, kidney, and brain of mice.

Bulletin of environmental contamination and toxicology 20030301

Investigations into the potential neurotoxicity induced by diselenides in mice and rats.

Toxicology 20030201

Anti-inflammatory and antinociceptive activity of diphenyl diselenide.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030201

Voltage-dependent ebselen and diorganochalcogenides inhibition of 45Ca2+ influx into brain synaptosomes.

Journal of biochemical and molecular toxicology 20030101

Reaction of diphenyl diselenide with hydrogen peroxide and inhibition of delta-aminolevulinate dehydratase from rat liver and cucumber leaves.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020601

Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain.

Neurochemical research 20020401

Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo.

Brain research 20010706

Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice.

Pharmacology & toxicology 20010301