1-Pyrrolidinamine
| Title | Journal |
|---|---|
| Metabolism, excretion, and pharmacokinetics of ((3,3-difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone, a dipeptidyl peptidase inhibitor, in rat, dog and human. | Drug metabolism and disposition: the biological fate of chemicals 20121101 |
| Synthesis and pharmacological investigation of azaphthalazinone human histamine H(1) receptor antagonists. | Bioorganic & medicinal chemistry 20121015 |
| Highly efficient asymmetric anti-Mannich reactions of carbonyl compounds with N-carbamoyl imines catalyzed by amino-thiourea organocatalysts. | Organic & biomolecular chemistry 20120514 |
| Viral hemorrhagic fevers: advancing the level of treatment. | BMC medicine 20120101 |
| Structural insights from binding poses of CCR2 and CCR5 with clinically important antagonists: a combined in silico study. | PloS one 20120101 |
| Molecular dynamics simulation study and hybrid pharmacophore model development in human LTA4H inhibitor design. | PloS one 20120101 |
| Rationalizing tight ligand binding through cooperative interaction networks. | Journal of chemical information and modeling 20111227 |
| 3-Aminopyrrolidine-4-carboxylic acid as versatile handle for internal labeling of pyrrolidinyl PNA. | Bioorganic & medicinal chemistry letters 20111101 |
| A novel biotransformation of alkyl aminopyrrolidine to aminopiperidine ring by human CYP3A. | Drug metabolism and disposition: the biological fate of chemicals 20110901 |
| Two solutions for the same problem: multiple binding modes of pyrrolidine-based HIV-1 protease inhibitors. | Journal of molecular biology 20110722 |
| Targeting nicotine addiction: the possibility of a therapeutic vaccine. | Drug design, development and therapy 20110101 |
| Characterisation and identification of the human N+-glucuronide metabolite of cediranib. | Journal of pharmaceutical and biomedical analysis 20101102 |
| Reflections on my career in analytical chemistry and biochemistry. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20101008 |
| Conformational preferences of proline analogues with a fused benzene ring. | The journal of physical chemistry. B 20100916 |
| A medicinal chemist's guide to molecular interactions. | Journal of medicinal chemistry 20100722 |
| Improving the developability profile of pyrrolidine progesterone receptor partial agonists. | Bioorganic & medicinal chemistry letters 20100101 |
| Heterogeneously catalyzed asymmetric hydrogenation of C=C bonds directed by surface-tethered chiral modifiers. | Journal of the American Chemical Society 20091014 |
| Design of novel aminopyrrolidine factor Xa inhibitors from a screening hit. | European journal of medicinal chemistry 20090701 |
| Photoinduced charge transfer and electrochemical properties of triphenylamine I(h)-Sc3N@C80 donor-acceptor conjugates. | Journal of the American Chemical Society 20090610 |
| The behavior of Gliclazide in solution and in the solid state: a case of organic compound presenting a solid-solution structure. | Magnetic resonance in chemistry : MRC 20090601 |
| Protonation of the side group in beta- and gamma-aminated proline analogues: effects on the conformational preferences. | The Journal of organic chemistry 20090417 |
| Access to pyrrolidine imino sugars via tin(II)-mediated aldol reactions of bislactim ethers: synthesis of 2,5-dideoxy-2,5-imino-D-glucitol. | Organic & biomolecular chemistry 20081107 |
| Conformational preferences of beta- and gamma-aminated proline analogues. | The journal of physical chemistry. B 20081106 |
| catena-Poly[[dibromidomercury(II)]-μ-3-(1-methyl-pyrrolidin-2-yl)pyridine-κN:N']. | Acta crystallographica. Section E, Structure reports online 20081001 |
| catena-Poly[[diiodidomercury(II)]-μ-nicotine-κN:N']. | Acta crystallographica. Section E, Structure reports online 20080801 |
| Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity. | Journal of medicinal chemistry 20080710 |
| Medicinal applications of fullerenes. | International journal of nanomedicine 20071201 |
| Synthesis and structure-activity relationships of potent antitumor active quinoline and naphthyridine derivatives. | Anti-cancer agents in medicinal chemistry 20071101 |
| Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors. | Bioorganic & medicinal chemistry 20070301 |
| 1H NMR spectroscopic studies of the conformational isomers of pyrrolidinofullerenes. | Chemistry (Weinheim an der Bergstrasse, Germany) 20070101 |
| Treatment of overactive bladder in the aging population: focus on darifenacin. | Clinical interventions in aging 20061201 |
| A fluorine scan at the catalytic center of thrombin: C--F, C--OH, and C--OMe bioisosterism and fluorine effects on pKa and log D values. | ChemMedChem 20060601 |
| Evolution of a strategy for the synthesis of structurally complex batzelladine alkaloids. Enantioselective total synthesis of the proposed structure of batzelladine F and structural revision. | Journal of the American Chemical Society 20060301 |
| The clinical pharmacokinetics of darifenacin. | Clinical pharmacokinetics 20060101 |
| Practical synthesis of the new carbapenem antibiotic ertapenem sodium. | The Journal of organic chemistry 20050916 |
| Supplementing pharmaceutical analysis techniques using radiotracers. | Journal of pharmaceutical sciences 20040501 |
| Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 2. | Journal of medicinal chemistry 20040408 |
| Heterocyclic aminopyrrolidine derivatives as melatoninergic agents. | Bioorganic & medicinal chemistry letters 20031215 |
| The nicotinic pharmacophore: thermodynamics of the hydrogen-bonding complexation of nicotine, nornicotine, and models. | The Journal of organic chemistry 20031017 |
| Asymmetric synthesis of unusual fused tricyclic beta-lactam structures via aza-cycloadditions/ring closing metathesis. | The Journal of organic chemistry 20030221 |
| Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1. | Journal of medicinal chemistry 20021205 |
| Design and synthesis of ethyl pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease. | Bioorganic & medicinal chemistry letters 20021202 |
| Synthesis and evaluation of potent pyrrolidine H(3) antagonists. | Bioorganic & medicinal chemistry letters 20021104 |
| Stereocontrolled synthesis of triazacyclopenta[cd]pentalenes by intramolecular 1,3-dipolar cycloaddition reactions of azomethine imines. | The Journal of organic chemistry 20021101 |
| Site of protonation of nicotine and nornicotine in the gas phase: pyridine or pyrrolidine nitrogen? | Journal of the American Chemical Society 20020904 |
| Effect of sequence on peptide geometry in 5-tert-butylprolyl type VI beta-turn mimics. | Journal of the American Chemical Society 20020320 |
| [60]Fullerene as a substituent. | Chemistry (Weinheim an der Bergstrasse, Germany) 20020301 |
| Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality. | Journal of medicinal chemistry 20020103 |