Home Other Building Blocks (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)aniline

(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)aniline

CAS No.:
162705-07-9
Catalog Number:
AG001TD4
Molecular Formula:
C18H21NO4
Molecular Weight:
315.3636
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
95%
In Stock USA
United States
$392
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Product Description
Catalog Number:
AG001TD4
Chemical Name:
(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)aniline
CAS Number:
162705-07-9
Molecular Formula:
C18H21NO4
Molecular Weight:
315.3636
MDL Number:
MFCD00937446
IUPAC Name:
2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]aniline
InChI:
InChI=1S/C18H21NO4/c1-20-15-8-7-12(9-14(15)19)5-6-13-10-16(21-2)18(23-4)17(11-13)22-3/h5-11H,19H2,1-4H3/b6-5-
InChI Key:
QSAMWSFELUCKOA-WAYWQWQTSA-N
SMILES:
COc1cc(/C=C\c2ccc(c(c2)N)OC)cc(c1OC)OC
UNII:
Z41106YR00
Properties
Complexity:
362  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
315.147g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
315.369g/mol
Monoisotopic Mass:
315.147g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
62.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.4  
Literature
Title Journal
Discovery of a potent tubulin polymerization inhibitor: synthesis and evaluation of water-soluble prodrugs of benzophenone analog. Bioorganic & medicinal chemistry letters 20101101
Identification of CKD-516: a potent tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors. Journal of medicinal chemistry 20100909
Synthesis and biological evaluation of combretastatin analogs as cell cycle inhibitors of the G1 to S transition in Saccharomyces cerevisiae. Bioorganic & medicinal chemistry letters 20100501
Synthesis and antitumor-evaluation of cyclopropyl-containing combretastatin analogs. Bioorganic & medicinal chemistry letters 20091215
Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4. Bioorganic & medicinal chemistry letters 20080915
Synthesis and biological activity of fluorinated combretastatin analogues. Journal of medicinal chemistry 20080508
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents. Journal of medicinal chemistry 20061019
Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41. Journal of medicinal chemistry 20050616
Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents. Journal of medicinal chemistry 20040520
Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. Journal of medicinal chemistry 20030213
Properties