Home Aminos 1,2,3-Oxadiazolium, 5-amino-3-(4-morpholinyl)-, chloride (1:1)

1,2,3-Oxadiazolium, 5-amino-3-(4-morpholinyl)-, chloride (1:1)

CAS No.:
16142-27-1
Catalog Number:
AG001SGL
Molecular Formula:
C6H13ClN4O2
Molecular Weight:
208.6460
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
≥99%
1 week
United States
$91
- +
50mg
≥99%
1 week
United States
$204
- +
100mg
≥99%
1 week
United States
$283
- +
500mg
≥99%
1 week
United States
$1098
- +
Product Description
Catalog Number:
AG001SGL
Chemical Name:
1,2,3-Oxadiazolium, 5-amino-3-(4-morpholinyl)-, chloride (1:1)
CAS Number:
16142-27-1
Molecular Formula:
C6H13ClN4O2
Molecular Weight:
208.6460
MDL Number:
MFCD00221615
IUPAC Name:
3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride
InChI:
InChI=1S/C6H10N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5,7H,1-4H2;1H
InChI Key:
NCGICGYLBXGBGN-UHFFFAOYSA-N
SMILES:
NC1=CN([NH2+]O1)N1CCOCC1.[Cl-]
EC Number:
605-254-1
Properties
Complexity:
222  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
206.057g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
206.63g/mol
Monoisotopic Mass:
206.057g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
49.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Cross-talk between lipid and protein carbonylation in a dynamic cardiomyocyte model of mild nitroxidative stress. Redox biology 20170401
Neuroprotective effects of Cyperus rotundus on SIN-1 induced nitric oxide generation and protein nitration: ameliorative effect against apoptosis mediated neuronal cell damage. Neurotoxicology 20130101
Comparative kinetics of thiol oxidation in two distinct free-radical generating systems: SIN-1 versus AAPH. Free radical research 20121001
Modulation of transcriptional mineralocorticoid receptor activity by nitrosative stress. Free radical biology & medicine 20120901
(13Z)- and (9Z)-lycopene isomers are major intermediates in the oxidative degradation of lycopene by cigarette smoke and Sin-1. Free radical research 20120701
Evaluation of novel antioxidant triterpenoid saponins from the halophyte Salicornia herbacea. Bioorganic & medicinal chemistry letters 20120701
Understanding the in-vivo relevance of S-nitrosothiols in insulin action. Canadian journal of physiology and pharmacology 20120701
Protein kinase CK2 mediates peroxynitrite-induced heme oxygenase-1 expression in articular chondrocytes. International journal of molecular medicine 20120601
Peroxynitrite donor SIN-1 alters high-affinity choline transporter activity by modifying its intracellular trafficking. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120418
Peroxynitrite has potent pulmonary vasodilator activity in the rat. Canadian journal of physiology and pharmacology 20120401
Possible involvement of S-nitrosylation of brain cyclooxygenase-1 in bombesin-induced central activation of adrenomedullary outflow in rats. European journal of pharmacology 20120315
Increased neuronal glutathione and neuroprotection in GTRAP3-18-deficient mice. Neurobiology of disease 20120301
Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway. British journal of pharmacology 20120101
The peroxynitrite donor 3-morpholinosydnonimine activates Nrf2 and the UPR leading to a cytoprotective response in endothelial cells. Cellular signalling 20120101
Taurine reduces nitrosative stress and nitric oxide synthase expression in high glucose-exposed human Schwann cells. Experimental neurology 20120101
Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease. PloS one 20120101
Neoechinulin a imparts resistance to acute nitrosative stress in PC12 cells: a potential link of an elevated cellular reserve capacity for pyridine nucleotide redox turnover with cytoprotection. Biological & pharmaceutical bulletin 20120101
Bicarbonate plays a critical role in the generation of cytotoxicity during SIN-1 decomposition in culture medium. Oxidative medicine and cellular longevity 20120101
Attenuated vasodilatation in lambs with endogenous and exogenous activation of cGMP signaling: role of protein kinase G nitration. Journal of cellular physiology 20111201
High glucose induced rat aorta vascular smooth muscle cell oxidative injury: involvement of protein tyrosine nitration. Journal of physiology and biochemistry 20111201
Threshold of peroxynitrite cytotoxicity in bovine pulmonary artery endothelial and smooth muscle cells. Toxicology in vitro : an international journal published in association with BIBRA 20111201
Administration of a nitric oxide donor inhibits mglA expression by intracellular Francisella tularensis and counteracts phagosomal escape and subversion of TNF-α secretion. Journal of medical microbiology 20111101
Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice. The Journal of clinical investigation 20111003
Upregulation of neuronal nitric oxide synthase in the periphery promotes pain hypersensitivity after peripheral nerve injury. Neuroscience 20110908
In vitro inhibition of human and rat platelets by NO donors, nitrosoglutathione, sodium nitroprusside and SIN-1, through activation of cGMP-independent pathways. Pharmacological research 20110901
In dialyzed squid axons oxidative stress inhibits the Na+/Ca2+ exchanger by impairing the Cai2+-regulatory site. American journal of physiology. Cell physiology 20110901
Protein kinase C mediates peroxynitrite toxicity to oligodendrocytes. Molecular and cellular neurosciences 20110901
Myricetin affords protection against peroxynitrite-mediated DNA damage and hydroxyl radical formation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901
Detection of peroxynitrite accumulation in Arabidopsis thaliana during the hypersensitive defense response. Nitric oxide : biology and chemistry 20110801
Effects of modulating in vivo nitric oxide production on the incidence and severity of PDE4 inhibitor-induced vascular injury in Sprague-Dawley rats. Toxicological sciences : an official journal of the Society of Toxicology 20110701
Peroxynitrite treatment reduces adenosine uptake via the equilibrative nucleoside transporter in rat astrocytes. Neuroscience letters 20110701
Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts. Free radical biology & medicine 20110601
Cytotoxicity and genotoxicity studies of two free-radical generators (AAPH and SIN-1) in human microvascular endothelial cells (HMEC-1) and human peripheral lymphocytes. Mutation research 20110518
A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells. European journal of pharmacology 20110511
5-HT1A autoreceptor modulation of locomotor activity induced by nitric oxide in the rat dorsal raphe nucleus. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20110401
Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans. Clinical science (London, England : 1979) 20110301
Early disruption of the actin cytoskeleton in cultured cerebellar granule neurons exposed to 3-morpholinosydnonimine-oxidative stress is linked to alterations of the cytosolic calcium concentration. Cell calcium 20110301
Apoptosis of hepatic stellate cells mediated by specific protein nitration. Biochemical pharmacology 20110201
Similarity and dissimilarity of thiols as anti-nitrosative agents in the nitric oxide-superoxide system. Biochemical and biophysical research communications 20110121
3-morpholinosydnonimine participates in the attenuation of neointima formation via inhibition of annexin A2-mediated vascular smooth muscle cell migration. Proteomics 20110101
Intimal hyperplasia in balloon dilated coronary arteries is reduced by local delivery of the NO donor, SIN-1 via a cGMP-dependent pathway. BMC cardiovascular disorders 20110101
S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats. Journal of neuroinflammation 20110101
Dorsal raphe nucleus regulation of a panic-like defensive behavior evoked by chemical stimulation of the rat dorsal periaqueductal gray matter. Behavioural brain research 20101201
Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite. Biochemical pharmacology 20101015
Protective effects of flavonoids against oxidative stress induced by simulated microgravity in SH-SY5Y cells. Neurochemical research 20100901
Inhibition of nitric oxide synthase during sepsis: revival because of isoform selectivity? Shock (Augusta, Ga.) 20100901
[The pharmacology of nitric oxide and nitrates]. Pharmazie in unserer Zeit 20100901
Investigation of relaxant effects of new agents affecting nitric oxide/cyclic guanosine monophosphate pathway on sheep oddi sphincter. Pancreas 20100801
Nitrosation-modulating effect of ascorbate in a model dynamic system of coexisting nitric oxide and superoxide. Free radical research 20100501
Potent inhibition of peroxynitrite-induced DNA strand breakage and hydroxyl radical formation by dimethyl sulfoxide at very low concentrations. Experimental biology and medicine (Maywood, N.J.) 20100501
cAMP-independent activation of protein kinase A by the peroxynitrite generator SIN-1 elicits positive inotropic effects in cardiomyocytes. Journal of molecular and cellular cardiology 20100401
Metallocorroles as cytoprotective agents against oxidative and nitrative stress in cellular models of neurodegeneration. Journal of neurochemistry 20100401
eNOS plays a major role in adiponectin synthesis in adipocytes. American journal of physiology. Endocrinology and metabolism 20100401
Morin modulates the oxidative stress-induced NF-kappaB pathway through its anti-oxidant activity. Free radical research 20100401
IL-8 production by macrophages is synergistically enhanced when cigarette smoke is combined with TNF-alpha. Biochemical pharmacology 20100301
Group IIA secretory phospholipase A2 (GIIA) mediates apoptotic death during NMDA receptor activation in rat primary cortical neurons. Journal of neurochemistry 20100301
The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion. European journal of pharmacology 20100210
Ethyl pyruvate inhibits peroxynitrite-induced DNA damage and hydroxyl radical generation: implications for neuroprotection. Neurochemical research 20100201
Spinal and peripheral mechanisms involved in the enhancement of morphine analgesia in acutely inflamed mice. Cellular and molecular neurobiology 20100101
Arginase contributes to endothelial cell oxidative stress in response to plasma from women with preeclampsia. Cardiovascular research 20100101
Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells. Neurochemistry international 20100101
Determination of glutathione, mitochondrial transmembrane potential, and cytotoxicity in H9c2 cardiomyoblasts exposed to reactive oxygen and nitrogen species. Methods in molecular biology (Clifton, N.J.) 20100101
Cigarette smoke and human plasma lycopene depletion. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Geniposide induces the expression of heme oxygenase-1 via PI3K/Nrf2-signaling to enhance the antioxidant capacity in primary hippocampal neurons. Biological & pharmaceutical bulletin 20100101
Nitric oxide-dependent pigment migration induced by ultraviolet radiation in retinal pigment cells of the crab Neohelice granulata. Photochemistry and photobiology 20100101
Inhibition of peroxynitrite-mediated DNA strand cleavage and hydroxyl radical formation by aspirin at pharmacologically relevant concentrations: implications for cancer intervention. Biochemical and biophysical research communications 20091204
Elevated plasma concentration of NO and cGMP may be responsible for the decreased platelet aggregation and platelet leukocyte conjugation in platelets hypo-responsive to catecholamines. Platelets 20091201
Nitric oxide-induced IL-8 expression is mediated by NF-kappaB and AP-1 in gastric epithelial AGS cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091201
Peroxynitrite mediates muscle insulin resistance in mice via nitration of IRbeta/IRS-1 and Akt. Toxicology and applied pharmacology 20091115
Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091101
P38 MAP kinase in valve interstitial cells is activated by angiotensin II or nitric oxide/peroxynitrite, but reduced by Toll-like receptor-2 stimulation. The Journal of heart valve disease 20091101
Inhibition of the soluble epoxide hydrolase by tyrosine nitration. The Journal of biological chemistry 20091009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
Spin trapping and cytoprotective properties of fluorinated amphiphilic carrier conjugates of cyclic versus linear nitrones. Chemical research in toxicology 20090901
Chemical model systems for cellular nitros(yl)ation reactions. Free radical biology & medicine 20090815
NOC-9, a selective nitric oxide donor, induces flight reactions in the dorsolateral periaqueductal gray of rats by activating soluble guanylate cyclase. Neuroscience letters 20090807
Cytoprotective effect of lignans from Forsythia suspensa against peroxynitrite-induced LLC-PK1 cell damage. Phytotherapy research : PTR 20090701
Bilberry and its main constituents have neuroprotective effects against retinal neuronal damage in vitro and in vivo. Molecular nutrition & food research 20090701
SIN-1 cytotoxicity to PC12 cells is mediated by thiol-sensitive short-lived substances generated through SIN-1 decomposition in culture medium. Nitric oxide : biology and chemistry 20090601
PTR1-dependent synthesis of tetrahydrobiopterin contributes to oxidant susceptibility in the trypanosomatid protozoan parasite Leishmania major. Current genetics 20090601
Tempol protection of spinal cord mitochondria from peroxynitrite-induced oxidative damage. Free radical research 20090601
Peroxynitrite induces gene expression in intervertebral disc cells. Spine 20090515
Physiopathological effects of the NO donor 3-morpholinosydnonimine on rat cortical synaptosomes. Neurochemical research 20090501
Modification of surfactant protein D by reactive oxygen-nitrogen intermediates is accompanied by loss of aggregating activity, in vitro and in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090501
Nitric oxide donor-mediated inhibition of phosphorylation shows that light-mediated degradation of photosystem II D1 protein and phosphorylation are not tightly linked. Planta 20090501
Nitric oxide- and cGMP-active compounds affect the discharge of substantia nigra pars reticulata neurons: in vivo evidences in the rat. Journal of neural transmission (Vienna, Austria : 1996) 20090501
Hemin-H2O2-NO2(-) induced protein oxidation and tyrosine nitration are different from those of SIN-1: a study on glutamate dehydrogenase nitrative/oxidative modification. The international journal of biochemistry & cell biology 20090401
Cruciferous dithiolethione-mediated coordinated induction of total cellular and mitochondrial antioxidants and phase 2 enzymes in human primary cardiomyocytes: cytoprotection against oxidative/electrophilic stress and doxorubicin toxicity. Experimental biology and medicine (Maywood, N.J.) 20090401
Reactive nitrogen species switch on early extracellular matrix remodeling via induction of MMP1 and TNFalpha. Gastroenterology 20090401
Cyclic guanosine monophosphate signaling cascade mediates pigment aggregation in freshwater shrimp chromatophores. The Biological bulletin 20090401
Nitric oxide produces HLA-G nitration and induces metalloprotease-dependent shedding creating a tolerogenic milieu. Immunology 20090301
Changes in the proteome and infectivity of Leishmania infantum induced by in vitro exposure to a nitric oxide donor. International journal of medical microbiology : IJMM 20090301
Morphological and physiological study of the cardiac NOS/NO system in the Antarctic (Hb-/Mb-) icefish Chaenocephalus aceratus and in the red-blooded Trematomus bernacchii. Nitric oxide : biology and chemistry 20090301
Alpha-lipoic acid potently inhibits peroxynitrite-mediated DNA strand breakage and hydroxyl radical formation: implications for the neuroprotective effects of alpha-lipoic acid. Molecular and cellular biochemistry 20090301
The metalloporphyrin FeTPPS but not by cyclosporin A antagonizes the interaction of peroxynitrate and hydrogen peroxide on cardiomyocyte cell death. Naunyn-Schmiedeberg's archives of pharmacology 20090201
Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in amyotrophic lateral sclerosis. Glia 20090115
Cisplatin upregulates mitochondrial nitric oxide synthase and peroxynitrite formation to promote renal injury. Toxicology and applied pharmacology 20090115
Peroxynitrite participates in mechanisms involved in capacitation of cryopreserved cattle. Animal reproduction science 20090101
Antioxidant activity of bisabolol: inhibitory effects on chemiluminescence of human neutrophil bursts and cell-free systems. Pharmacology 20090101
Effect of nitric oxide donors on NADPH oxidase signaling pathway in human neutrophils in vitro. Immunobiology 20090101
Urate oxidase knockdown decreases oxidative stress in a murine hepatic cell line. Oxidative medicine and cellular longevity 20090101
Effects of maté tea intake on ex vivo LDL peroxidation induced by three different pathways. Nutrients 20090101
Synthesis and biological activities of neoechinulin A derivatives: new aspects of structure-activity relationships for neoechinulin A. Chemical & pharmaceutical bulletin 20081201
Induction of adaptive response and enhancement of PC12 cell tolerance by lipopolysaccharide primarily through the upregulation of glutathione S-transferase A3 via Nrf2 activation. Free radical biology & medicine 20081115
LDL protein nitration: implication for LDL protein unfolding. Archives of biochemistry and biophysics 20081101
Peroxynitrite augments fibroblast-mediated tissue remodeling via myofibroblast differentiation. American journal of physiology. Lung cellular and molecular physiology 20081101
Nitric oxide and peroxynitrite regulate transporter transcription in rat liver slices. Biological & pharmaceutical bulletin 20081001
The peroxynitrite donor 3-morpholinosydnonimine induces reversible changes in electrophysiological properties of neurons of the guinea-pig spinal cord. Neuroscience 20080922
Degradation of extracellular matrix by peroxynitrite/peroxynitrous acid. Free radical biology & medicine 20080901
Nitric oxide modulates the frog heart ventricle morphodynamics. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080901
Human neutrophil-pulmonary microvascular endothelial cell interactions in vitro: differential effects of nitric oxide vs. peroxynitrite. Microvascular research 20080801
Nitric oxide (NO)-releasing aspirin and (NO) donors in protection of gastric mucosa against stress. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801
Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide. Cellular microbiology 20080701
Biphasic effect of SIN-1 is reliant upon cardiomyocyte contractile state. Free radical biology & medicine 20080701
In vivo electrophysiology of dopamine-denervated striatum: focus on the nitric oxide/cGMP signaling pathway. Synapse (New York, N.Y.) 20080601
Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis. Osteoarthritis and cartilage 20080501
Cytoprotective effect of baicalein against peroxynitrite-induced toxicity in LLC-PK(1) cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080501
Hepatic portal venous delivery of a nitric oxide synthase inhibitor enhances net hepatic glucose uptake. American journal of physiology. Endocrinology and metabolism 20080401
Participation of nitric oxide in the color change induced by UV radiation in the crab Chasmagnathus granulatus. Pigment cell & melanoma research 20080401
Lignans from the fruits of Forsythia suspensa. Bioorganic & medicinal chemistry letters 20080315
Activity and subcellular trafficking of the sodium-coupled choline transporter CHT is regulated acutely by peroxynitrite. Molecular pharmacology 20080301
Modulation of hTREK-1 by carbon monoxide. Neuroreport 20080212
Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog. American journal of physiology. Endocrinology and metabolism 20080201
Glutathione production is regulated via distinct pathways in stressed and non-stressed cortical neurons. Brain research 20080116
Targeting of phospholamban by peroxynitrite decreases beta-adrenergic stimulation in cardiomyocytes. Cardiovascular research 20080115
Neuroglobin protects against nitric oxide toxicity. Neuroscience letters 20080110
Role of nitric oxide/cyclic GMP pathway in regulating spontaneous excitations in detrusor smooth muscle of the guinea-pig bladder. Neurourology and urodynamics 20080101
Tuning adenosine A1 and A2A receptors activation mediates L-citrulline-induced inhibition of [3H]-acetylcholine release depending on nerve stimulation pattern. Neurochemistry international 20080101
The role of nitric oxide and cGMP in somatostatin's protection against retinal ischemia. Investigative ophthalmology & visual science 20080101
Use of recombinant iron-superoxide dismutase as a marker of nitrative stress. Methods in enzymology 20080101
Nitric oxide induces gene expression of Jumonji and retinoblastoma 2 protein while reducing expression of atrial natriuretic peptide precursor type B in cardiomyocytes. Folia biologica 20080101
Luminescence experiments involved in the mechanism of streptozotocin diabetes and cataract formation. Luminescence : the journal of biological and chemical luminescence 20080101
Active compounds isolated from traditional Chinese prescription Wen-Pi-Tang protecting against peroxynitrite-induced LLC-PK(1) cell damage. The American journal of Chinese medicine 20080101
Peroxynitrite donor impairs excitability of hippocampal CA1 neurons by inhibiting voltage-gated potassium currents. Toxicology letters 20071210
Interferon-beta is neuroprotective against the toxicity induced by activated microglia. Brain research 20071107
Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death. Neurobiology of aging 20071101
The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases. Journal of neurochemistry 20071101
Chemical-biological fingerprinting: probing the properties of DNA lesions formed by peroxynitrite. Chemical research in toxicology 20071101
Nitric oxide modulates ionic transport in the isolated intestine of the eel, Anguilla anguilla. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20071001
Nitric oxide-donating aspirin (NCX 4016) inhibits neointimal thickening in a pig model of saphenous vein-carotid artery interposition grafting: a comparison with aspirin and morpholinosydnonimine (SIN-1). The Journal of thoracic and cardiovascular surgery 20071001
Structure-activity relationships of neoechinulin A analogues with cytoprotection against peroxynitrite-induced PC12 cell death. The Journal of antibiotics 20071001
Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. The Journal of biological chemistry 20070928
Nitration of a critical tyrosine residue in the allosteric inhibitor site of muscle glycogen phosphorylase impairs its catalytic activity. Journal of molecular biology 20070928
Inhibition of peroxynitrite precursors, NO and O2, at the onset of reperfusion improves myocardial recovery. Resuscitation 20070901
Central nitric oxide blocks vasopressin, oxytocin and atrial natriuretic peptide release and antidiuretic and natriuretic responses induced by central angiotensin II in conscious rats. Experimental physiology 20070901
Properties of spontaneous Ca2+ transients recorded from interstitial cells of Cajal-like cells of the rabbit urethra in situ. The Journal of physiology 20070901
Nitric oxide regulates growth cone filopodial dynamics via ryanodine receptor-mediated calcium release. The European journal of neuroscience 20070901
Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers. Journal of neuroscience research 20070801
Independency of myocardial stunning of endothelial stunning? Basic research in cardiology 20070701
The NO donor SIN-1 improves intestinal-arterial P(CO(2)) gap in experimental endotoxemia: an animal study. Acta anaesthesiologica Scandinavica 20070701
Signal transduction pathways affected by nitric oxide donors during neutrophil functional response in vitro. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070701
SNAP and SIN-1 increase brain production of kynurenic acid. European journal of pharmacology 20070601
Cyclic AMP dependent down regulation in the relaxation of smooth muscle cells of cat esophagitis. Archives of pharmacal research 20070601
Nitric oxide differentially regulates the gene expression of caspase genes but not some autophagic genes. Nitric oxide : biology and chemistry 20070501
Glycyrrhizin protection against 3-morpholinosydnonime-induced mitochondrial dysfunction and cell death in lung epithelial cells. Life sciences 20070417
Lens thiol depletion by peroxynitrite. Protective effect of pyruvate. Molecular and cellular biochemistry 20070401
Nitric oxide involvement in histamine-mediated PANC-1 cells growth. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070401
Peroxynitrite mild nitration of albumin and LDL-albumin complex naturally present in plasma and tyrosine nitration rate-albumin impairs LDL nitration. Free radical research 20070301
Modulation of voltage-gated Ca2+ current in vestibular hair cells by nitric oxide. Journal of neurophysiology 20070201
Generation and release of nitrotyrosine O-sulfate by HepG2 human hepatoma cells upon SIN-1 stimulation: identification of SULT1A3 as the enzyme responsible. The Biochemical journal 20070115
Nitric oxide-dependent vasodilatation by ethanolic extract of Hancornia speciosa via phosphatidyl-inositol 3-kinase. Journal of ethnopharmacology 20070103
A comparative study of the effects of molsidomine and 3-morpholinosydnonimine on the redox status of rat erythrocytes and reticulocytes. Cell biochemistry and function 20070101
Pulmonary vascular reactivity of spontaneously hypertensive rats is exacerbated in response to the central administration of exogenous nitric oxide. Clinical and experimental pharmacology & physiology 20070101
Nitric oxide-induced cell death in the heart: the role of autophagy. Autophagy 20070101
Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP. Experimental neurology 20061201
Effects of oxidizing and reducing agents on ovine pulmonary artery responses to nitric oxide donors, sodium nitroprusside and 3-morpholino-sydnonimine. Indian journal of experimental biology 20061201
Inducible nitric oxide synthase (iNOS) activity could be responsible for resistance or sensitivity to IFN-gamma-induced apoptosis in several human hepatoma cell lines. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20061201
Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation. Life sciences 20061110
Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience 20061108
Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nature chemical biology 20061101
Does central nitric oxide elicit pulmonary hypertension in conscious rats? Respiratory physiology & neurobiology 20061027
Thioredoxin reduces post-ischemic myocardial apoptosis by reducing oxidative/nitrative stress. British journal of pharmacology 20061001
Nitric oxide and peroxynitrite have different antiviral effects against hantavirus replication and free mature virions. European journal of immunology 20061001
Peroxynitrite induces HO-1 expression via PI3K/Akt-dependent activation of NF-E2-related factor 2 in PC12 cells. Free radical biology & medicine 20061001
Metallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson disease. Experimental biology and medicine (Maywood, N.J.) 20061001
Effects of nitric oxide-active drugs on the discharge of subthalamic neurons: microiontophoretic evidence in the rat. The European journal of neuroscience 20061001
Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis. Circulation 20060926
Effect of lycopene and beta-carotene on peroxynitrite-mediated cellular modifications. Toxicology and applied pharmacology 20060915
Modulation of peroxynitrite-induced fibroblast injury by hesperetin: a role for intracellular scavenging and modulation of ERK signalling. Biochemical and biophysical research communications 20060908
Direct comparison of relaxation and cGMP production in human coronary by-pass grafts in response to stimulation with natriuretic peptides and a nitric oxide donor. Clinical science (London, England : 1979) 20060901
The role of reactive nitrogen species and cigarette smoke in activation of transcription factor NF-kappaB and implication to inflammatory processes. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20060901
Bimodal effect of nitric oxide in the enzymatic activity of indoleamine 2,3-dioxygenase in human monocytic cells. Immunology letters 20060815
Dynorphin-mediated antinociceptive effects of L-arginine and SIN-1 (an NO donor) in mice. Brain research bulletin 20060731
Reactive nitrogen species induce nuclear factor-kappaB-mediated protein degradation in skeletal muscle cells. Free radical biology & medicine 20060615
Peroxynitrite generation and tyrosine nitration in defense responses in tobacco BY-2 cells. Plant & cell physiology 20060601
Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage. Neuroscience letters 20060515
Effects of peroxynitrite and lipopolysaccharide on mitotic activity of C6 glioma cells. Neuroscience letters 20060508
Nitric oxide stimulates the erythrocyte for ascorbate recycling. Nitric oxide : biology and chemistry 20060501
Heme catalyzes tyrosine 385 nitration and inactivation of prostaglandin H2 synthase-1 by peroxynitrite. Journal of lipid research 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Carbon monoxide protects PC12 cells from peroxynitrite-induced apoptotic death by preventing the depolarization of mitochondrial transmembrane potential. Biochemical and biophysical research communications 20060414
Anti-inflammatory properties of micropatterned titanium coatings. Journal of biomedical materials research. Part A 20060401
Co-administration of glutathione and nitric oxide enhances insulin sensitivity in Wistar rats. British journal of pharmacology 20060401
Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects. Psychopharmacology 20060401
Antioxidant effects of quinoline alkaloids and 2,4-di-tert-butylphenol isolated from Scolopendra subspinipes. Biological & pharmaceutical bulletin 20060401
Does central nitric oxide chronically modulate the acute hypoxic ventilatory response in conscious rats? Acta physiologica (Oxford, England) 20060401
Peroxynitrite induces F-actin depolymerization and blockade of myosin ATPase stimulation. Biochemical and biophysical research communications 20060331
Inhibition of skeletal muscle S1-myosin ATPase by peroxynitrite. Biochemistry 20060321
Reactions of *NO2 with chromium(III) complexes with histamine and pyridoxamine ligands studied by the stopped-flow technique. Analytical biochemistry 20060315
Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: modulatory effect of cellular G6PD status. Journal of agricultural and food chemistry 20060308
Therapeutic action of cannabinoid on axonal injury induced by peroxynitrite. Brain research 20060303
Protection of peroxynitrite-induced DNA damage by dietary antioxidants. Archives of pharmacal research 20060301
Coronary vasomotor response to the selective B1-kinin-receptor agonist Des-Arg9-bradykinin in humans. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060201
S-phase arrest by reactive nitrogen species is bypassed by okadaic acid, an inhibitor of protein phosphatases PP1/PP2A. Free radical biology & medicine 20060115
Involvement of guanylyl cyclase, protein kinase A and Na+ K+ ATPase in relaxations of bovine isolated bronchioles induced by GEA 3175, an NO donor. Pulmonary pharmacology & therapeutics 20060101
Delta opioid agonists attenuate TAT(1-72)-induced oxidative stress in SK-N-SH cells. Neurotoxicology 20060101
Estrogen attenuates gp120- and tat1-72-induced oxidative stress and prevents loss of dopamine transporter function. Synapse (New York, N.Y.) 20060101
Exogenous N-linoleoyl tyrosine marker as a tool for the characterization of cellular oxidative stress in macrophages. Free radical research 20060101
Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arteriosclerosis, thrombosis, and vascular biology 20051201
Effects of peroxynitrite and superoxide radicals on endothelial monolayer permeability: potential role of peroxynitrite in preeclampsia. Journal of the Society for Gynecologic Investigation 20051201
Inhibition of mitochondrial aldehyde dehydrogenase by nitric oxide-mediated S-nitrosylation. FEBS letters 20051107
Role of endogenous melatonin in the oxidative homeostasis of the extracellular striatal compartment: a microdialysis study in PC12 cells in vitro and in the striatum of freely moving rats. Journal of pineal research 20051101
Ethanol metabolism alters interferon gamma signaling in recombinant HepG2 cells. Hepatology (Baltimore, Md.) 20051101
Exogenous nitric oxide centrally enhances pulmonary reactivity in the normal and hypertensive rat. Clinical and experimental pharmacology & physiology 20051101
Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation. The Biochemical journal 20051015
Cardiotrophin-1 protects cortical neuronal cells against free radical-induced injuries in vitro. Neuroscience letters 20051014
Adenosine/nitric oxide crosstalk in the branchial circulation of Squalus acanthias and Anguilla anguilla. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20051001
Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage. Journal of neurochemistry 20051001
Peroxynitrite generated at the level produced by spinal cord injury induces peroxidation of membrane phospholipids in normal rat cord: reduction by a metalloporphyrin. Journal of neurotrauma 20051001
Initiation of a superoxide-dependent chain oxidation of lactate dehydrogenase-bound NADH by oxidants of low and high reactivity. Free radical research 20051001
Angiotensin II induces tyrosine nitration and activation of ERK1/2 in vascular smooth muscle cells. FEBS letters 20050912
Interstitial telomeric DNA sequences of Chinese hamster cells are hypersensitive to nitric oxide damage, and DNA-PKcs has a specific local role in its repair. Genes, chromosomes & cancer 20050901
The importance of the phagocytes' innate response in resolution of the infection induced by a low virulent Candida albicans mutant. Scandinavian journal of immunology 20050901
Impairment of the activity of the xenobiotic-metabolizing enzymes arylamine N-acetyltransferases 1 and 2 (NAT1/NAT2) by peroxynitrite in mouse skeletal muscle cells. FEBS letters 20050829
Mitogen-activated protein kinases (MAPKs) mediate SIN-1/ glucose deprivation-induced death in rat primary astrocytes. Archives of pharmacal research 20050801
Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M(3) receptor-dependent. European journal of pharmacology 20050704
Peroxynitrite provides the peroxide tone for PGHS-2-dependent prostacyclin synthesis in vascular smooth muscle cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701
Adenosine and purine nucleosides prevent the disruption of mitochondrial transmembrane potential by peroxynitrite in rat primary astrocytes. Archives of pharmacal research 20050701
Protein phosphatase 1alpha is tyrosine-phosphorylated and inactivated by peroxynitrite in erythrocytes through the src family kinase fgr. Free radical biology & medicine 20050615
Flow cytometric evaluation of human neutrophil apoptosis during nitric oxide generation in vitro: the role of exogenous antioxidants. Mediators of inflammation 20050609
Peroxynitrite-mediated matrix metalloproteinase-2 activation in human hepatic stellate cells. FEBS letters 20050606
Hemorrhagic shock resuscitation affects early and selective mesenteric artery endothelial function through a free radical-dependent mechanism. Shock (Augusta, Ga.) 20050501
New glycosidase activated nitric oxide donors: glycose and 3-morphorlinosydnonimine conjugates. The Journal of organic chemistry 20050429
Curcumin overcomes the inhibitory effect of nitric oxide on Leishmania. Parasitology research 20050401
Propofol inhibits caspase-3 in astroglial cells: role of heme oxygenase-1. Current neurovascular research 20050401
Nitric oxide stimulates gamma-aminobutyric acid release and inhibits glycine release in retina. The Journal of comparative neurology 20050314
The effects of intraspinal L-NOARG or SIN-1 on the control by descending pathways of incisional pain in rats. Life sciences 20050311
Lack of synergistic effect of molsidomine and sildenafil on development of pulmonary hypertension in chronic hypoxic rats. European journal of pharmacology 20050307
Inhibition of MG132-induced mitochondrial dysfunction and cell death in PC12 cells by 3-morpholinosydnonimine. Brain research 20050302
Protective role of Coptidis Rhizoma alkaloids against peroxynitrite-induced damage to renal tubular epithelial cells. The Journal of pharmacy and pharmacology 20050301
Alteration of cytosolic free calcium homeostasis by SIN-1: high sensitivity of L-type Ca2+ channels to extracellular oxidative/nitrosative stress in cerebellar granule cells. Journal of neurochemistry 20050201
NAD+ as a metabolic link between DNA damage and cell death. Journal of neuroscience research 20050101
alpha-keto-beta-methyl-n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores. Free radical biology & medicine 20041201
Propofol attenuates peroxynitrite-mediated DNA damage and apoptosis in cultured astrocytes: an alternative protective mechanism. Anesthesiology 20041201
Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041124
Benzodiazepine receptor and serotonin 2A receptor modulate the aversive-like effects of nitric oxide in the dorsolateral periaqueductal gray of rats. Psychopharmacology 20041101
15-Deoxy-Delta12,14-prostaglandin J(2) protects against nitrosative PC12 cell death through up-regulation of intracellular glutathione synthesis. The Journal of biological chemistry 20041029
Signalling pathways in the nitric oxide donor-induced dopamine release in the striatum of freely moving rats: evidence that exogenous nitric oxide promotes Ca2+ entry through store-operated channels. Brain research 20041015
Intracellular pH-dependent peroxynitrite-evoked synergistic death of glucose-deprived astrocytes. Free radical biology & medicine 20041015
[Effects of nitric oxide donor on autoimmune myasthenia gravis in rats]. Zhonghua yi xue za zhi 20041002
Caspase-1 and poly (ADP-ribose) polymerase inhibitors may protect against peroxynitrite-induced neurotoxicity independent of their enzyme inhibitor activity. The European journal of neuroscience 20041001
Heme oxygenase-1 mediates up-regulation of adhesion molecule expression induced by peroxynitrite in endothelial cells. Journal of the Society for Gynecologic Investigation 20041001
No hemoglobin but NO: the icefish (Chionodraco hamatus) heart as a paradigm. The Journal of experimental biology 20041001
Protective effect of 1-methylated beta-carbolines against 3-morpholinosydnonimine-induced mitochondrial damage and cell viability loss in PC12 cells. Neurochemical research 20041001
Reactivity of 1,4-dihydropyridines toward SIN-1-derived peroxynitrite. Pharmaceutical research 20041001
Effects of endogenous and exogenous nitric oxide on electrical responses of circular smooth muscle isolated from the guinea-pig stomach antrum. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20041001
Nitroprusside stimulates mitochondrial aconitase gene expression through the cyclic adenosine 3',5'-monosphosphate signal transduction pathway in human prostate carcinoma cells. The Prostate 20040915
Highly selective and prolonged depletion of mitochondrial glutathione in astrocytes markedly increases sensitivity to peroxynitrite. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040915
Calcium mobilization is required for peroxynitrite-mediated enhancement of spontaneous transient outward currents in arteriolar smooth muscle cells. Free radical biology & medicine 20040915
Effects of L-arginine and SIN-1 on sleep and waking in the rat during both phases of the light-dark cycle. Life sciences 20040910
Increased release of excitatory amino acids by the actions of ATP and peroxynitrite on volume-regulated anion channels (VRACs) in astrocytes. Neurochemistry international 20040901
GEA 3162 decomposes to co-generate nitric oxide and superoxide and induces apoptosis in human neutrophils via a peroxynitrite-dependent mechanism. British journal of pharmacology 20040901
3-Morpholinylsydnonimine inhibits glutamatergic transmission in rat rostral ventrolateral medulla via peroxynitrite formation and adenosine release. Molecular pharmacology 20040901
Role of anions in nitric oxide-induced short-circuit current increase in isolated porcine ciliary processes. Investigative ophthalmology & visual science 20040901
Insulin sensitivity is mediated by the activation of the ACh/NO/cGMP pathway in rat liver. American journal of physiology. Gastrointestinal and liver physiology 20040901
Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo. Hepatology (Baltimore, Md.) 20040901
The sin in the aetiological concept of Johann Christian August Heinroth (1773-1843). Part 1: Between theology and psychiatry. Heinroth's concepts of 'whose being', 'freedom', 'reason' and 'disturbance of the soul'. History of psychiatry 20040901
Parasite killing in Plasmodium vivax malaria by nitric oxide: implication of aspartic protease inhibition. Journal of biochemistry 20040901
Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells. Circulation 20040831
Interference of 7,8-dihydroneopterin with peroxynitrite-mediated reactions. Biochemical and biophysical research communications 20040820
Nitric oxide attenuates cardiomyocytic apoptosis via diminished mitochondrial complex I up-regulation from cardiac ischemia-reperfusion injury under cardiopulmonary bypass. The Journal of thoracic and cardiovascular surgery 20040801
Reduction of insulin-stimulated glucose uptake by peroxynitrite is concurrent with tyrosine nitration of insulin receptor substrate-1. Biochemical and biophysical research communications 20040730
Potent inhibition of peroxynitrite-induced DNA strand breakage by ethanol: possible implications for ethanol-mediated cardiovascular protection. Pharmacological research 20040701
Inhibition of SIN-1-induced change in mitochondrial membrane permeability in PC12 cells by dopamine. Neurochemical research 20040701
Protective properties of neoechinulin A against SIN-1-induced neuronal cell death. Journal of biochemistry 20040701
Peroxynitrite decreases hemostasis in human plasma in vitro. Anesthesia and analgesia 20040701
Cell type-dependent release of nitric oxide and/or reactive nitrogenoxide species from intracellular SIN-1: effects on cellular NAD(P)H. Biological chemistry 20040701
PKC downstream of Pl3-kinase regulates peroxynitrite formation for Nrf2-mediated GSTA2 induction. Archives of pharmacal research 20040701
Vasodilatory effects of cholinergic agonists are greatly diminished in aorta from M3R-/- mice. European journal of pharmacology 20040616
Involvement of the mitogen-activated protein kinase cascade in peroxynitrite-mediated arachidonic acid release in vascular smooth muscle cells. American journal of physiology. Cell physiology 20040601
Mutations in the extracellular loop of alpha-rENaC alter sensitivity to amiloride and reactive species. American journal of physiology. Renal physiology 20040601
Effects of phosphodiesterase V inhibition on nitric oxide-mediated relaxation responses in guinea pig trachea. Pharmacology 20040601
[Transradial approach for diagnostic angiography]. Journal de radiologie 20040601
Dual role for poly(ADP-ribose)polymerase-1 and -2 and poly(ADP-ribose)glycohydrolase as DNA-repair and pro-apoptotic factors in rat germinal cells exposed to nitric oxide donors. Biochimica et biophysica acta 20040528
Nitric oxide activates glibenclamide-sensitive K+ channels in urinary bladder myocytes through a c-GMP-dependent mechanism. European journal of pharmacology 20040510
Overexpression of alpha-synuclein decreased viability and enhanced sensitivity to prostaglandin E(2), hydrogen peroxide, and a nitric oxide donor in differentiated neuroblastoma cells. Journal of neuroscience research 20040501
17beta-estradiol protects oligodendrocytes from cytotoxicity induced cell death. Journal of neurochemistry 20040501
Peroxynitrite inactivates tissue plasminogen activator. Anesthesia and analgesia 20040501
Endothelium-dependent relaxation of canine pulmonary artery after prolonged lung graft preservation in University of Wisconsin solution: role of L-arginine supplementation. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501
High and low gain switches for regulation of cAMP efflux concentration: distinct roles for particulate GC- and soluble GC-cGMP-PDE3 signaling in rabbit atria. Circulation research 20040416
Elements of the nitric oxide pathway can degrade TIMP-1 and increase gelatinase activity. Molecular vision 20040416
Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair. Free radical biology & medicine 20040415
Decomposition mechanism of 3-N-morpholinosydnonimine (SIN-1)--a density functional study on intrinsic structures and reactivities. Journal of molecular modeling 20040401
Comparison of toxic effects of nitric oxide and peroxynitrite on Uronema marinum (Ciliata: Scuticociliatida). Diseases of aquatic organisms 20040310
Xanthine oxidase converts nitric oxide to nitroxyl that inactivates the enzyme. Biochemical and biophysical research communications 20040305
Peroxynitrite decreases rabbit tissue factor activity in vitro. Anesthesia and analgesia 20040301
Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: a cellular and mechanistic study. The Journal of biological chemistry 20040227
Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxia-inducible factor-1alpha (HIF-1alpha) in explants of human pial arteries. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040201
Nitric oxide-induced carbonylation of Bcl-2, GAPDH and ANT precedes apoptotic events in insulin-secreting RINm5F cells. Experimental cell research 20040201
Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro. British journal of pharmacology 20040201
A common pathway of nitric oxide release from AZD3582 and glyceryl trinitrate. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040201
Nitric oxide and superoxide impair human placental amino acid uptake and increase Na+ permeability: implications for fetal growth. Free radical biology & medicine 20040201
Effect of L-ascorbic acid on the oxidative modification of apolipoprotein E in human very-low-density lipoprotein. Journal of nutritional science and vitaminology 20040201
Modulation of A1 adenosine receptor signaling by peroxynitrite. Biochemical pharmacology 20040115
Ionotropic glutamate-receptor antagonists inhibit the aversive effects of nitric oxide donor injected into the dorsolateral periaqueductal gray of rats. Psychopharmacology 20040101
Potent antioxidant properties of 4-hydroxyl-propranolol. The Journal of pharmacology and experimental therapeutics 20040101
The superoxide dismutase mimetic, tempol, blunts right ventricular hypertrophy in chronic hypoxic rats. British journal of pharmacology 20040101
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway. Anesthesia and analgesia 20040101
Peroxynitrite-induced apoptosis in photoreceptor cells. Current eye research 20040101
Effects of oxygen on the reactivity of nitrogen oxide species including peroxynitrite. Biological & pharmaceutical bulletin 20040101
Pro-oxidant properties and cytotoxicity of AZT-monophosphate and AZT. Cardiovascular toxicology 20040101
Protecting against peroxynitrite-mediated cytotoxicity in vascular smooth muscle cells via upregulating endogenous glutathione biosynthesis by 3H-1,2-dithiole-3-thione. Cardiovascular toxicology 20040101
Fire fly luciferin as antioxidant and light emitter: the evolution of insect bioluminescence. Luminescence : the journal of biological and chemical luminescence 20040101
Fluorescence measurements of steady state peroxynitrite production upon SIN-1 decomposition: NADH versus dihydrodichlorofluorescein and dihydrorhodamine 123. Journal of fluorescence 20040101
Novel chemiluminescence-inducing cocktails, part I: the role in light emission of combinations of luminal with SIN-1, selenite, albumin, glucose oxidase and Co2+. Inflammopharmacology 20040101
Novel chemiluminescence-inducing cocktails, part II: measurement of the anti-oxidant capacity of vitamins, thiols, body fluids, alcoholic beverages and edible oils. Inflammopharmacology 20040101
Role of the nitric oxide/cyclic GMP pathway and ascorbic acid in 3-morpholinosydnonimine (SIN-1)-induced increases in dopamine secretion from PC12 cells. A microdialysis in vitro study. Neuroscience letters 20031215
Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells. Cancer research 20031215
Oxidative and adhesive responses of human neutrophils to nitrovasodilators in vitro: the role of protein kinases. Mediators of inflammation 20031201
Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels. Arthritis and rheumatism 20031201
3-Morpholinosyndnonimine inhibits 5-hydroxytryptamine-induced phosphorylation of nitric oxide synthase in endothelial cells. Cellular and molecular biology (Noisy-le-Grand, France) 20031201
Cyclic AMP and cyclic GMP independent stimulation of ventricular calcium current by peroxynitrite donors in guinea pig myocytes. Journal of cellular physiology 20031101
Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1alpha. Leukemia 20031101
Peroxynitrite decreases dopamine's vasoconstrictive activity. Anesthesia and analgesia 20031101
Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection. Life sciences 20031017
Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore. Chemical research in toxicology 20031001
Protection by the Chinese prescription Wen-Pi-Tang against renal tubular LLC-PK1 cell damage induced by 3-morpholinosydnonimine. The Journal of pharmacy and pharmacology 20031001
Novel SIN-1 reactive intermediates modulate chloride secretion across murine airway cells. Free radical biology & medicine 20030915
Toxicity of nitric oxide and peroxynitrite to Photobacterium damselae subsp. piscicida. Fish & shellfish immunology 20030901
Role of nitric oxide in leukocyte-independent endothelial damage during experimental endotoxemia. Shock (Augusta, Ga.) 20030901
Dissociation of cGMP accumulation and relaxation in myometrial smooth muscle: effects of S-nitroso-N-acetylpenicillamine and 3-morpholinosyndonimine. Cellular signalling 20030801
Reactive oxygen species inhibited by titanium oxide coatings. Journal of biomedical materials research. Part A 20030801
The role of nitric oxide in systemic and hepatic haemodynamics in the rat in vivo. Naunyn-Schmiedeberg's archives of pharmacology 20030801
Molecular basis and characteristics of KATP channel in human corporal smooth muscle cells. International journal of impotence research 20030801
Human plasminogen is highly susceptible to peroxynitrite inactivation. Clinical chemistry and laboratory medicine 20030801
Role of intracellular calcium mobilization and cell-density-dependent signaling in oxidative-stress-induced cytotoxicity in HaCaT keratinocytes. The Journal of investigative dermatology 20030701
Local infusion of the nitric oxide donor Sin-1 after angioplasty. Effects on intimal hyperplasia in porcine coronary arteries. Acta radiologica (Stockholm, Sweden : 1987) 20030701
Effects of nitric oxide on morphology of isolated cochlear outer hair cells: possible involvement in sensorineural hearing loss. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20030701
Nitric oxide-induced inhibition on striatal cells and excitation on globus pallidus neurons: a microiontophoretic study in the rat. Neuroscience letters 20030605
Mitogen-activated protein kinases mediate peroxynitrite-induced cell death in human bronchial epithelial cells. American journal of physiology. Lung cellular and molecular physiology 20030601
Reactive nitrogen species block cell cycle re-entry through sustained production of hydrogen peroxide. American journal of respiratory cell and molecular biology 20030601
Peroxynitrite-induced oxidation of plasma lipids is enhanced in stable hemodialysis patients. Kidney international 20030601
Mitochondrial ATP-sensitive potassium channel: a novel site for neuroprotection. Investigative ophthalmology & visual science 20030601
Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons. Antioxidants & redox signaling 20030601
Peroxynitrite and NO+ donors form colored nitrite adducts with sinapinic acid: potential applications. Nitric oxide : biology and chemistry 20030601
Inactivation of platelet glycoprotein IIb/IIIa receptor by nitric oxide donor 3-morpholino-sydnonimine. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030601
In vitro reactive nitrating species toxicity in dissociated spinal motor neurons from NFL (-/-) and hNFL (+/+) transgenic mice. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20030601
NO/cyclic GMP pathway mediates the relaxation of feline lower oesophageal sphincter. Autonomic & autacoid pharmacology 20030601
Synthesis of beta-lactamase activated nitric oxide donors. Bioorganic & medicinal chemistry letters 20030519
Increased sensitivity to endothelial nitric oxide (NO) contributes to arterial normotension in mice with vascular smooth muscle-selective deletion of the atrial natriuretic peptide (ANP) receptor. The Journal of biological chemistry 20030516
Nitric oxide modulates striatal neuronal activity via soluble guanylyl cyclase: an in vivo microiontophoretic study in rats. Synapse (New York, N.Y.) 20030501
Role of specific adrenergic receptors in mediating the adrenocorticotropic hormone response to increased nitric oxide levels. Journal of neuroendocrinology 20030501
Protective activity of (-)-epicatechin 3-O-gallate against peroxynitrite-mediated renal damage. Free radical research 20030501
Grape and grape seed extract capacities at protecting LDL against oxidation generated by Cu2+, AAPH or SIN-1 and at decreasing superoxide THP-1 cell production. A comparison to other extracts or compounds. Free radical research 20030501
Nitric oxide disrupts VE-cadherin complex in murine microvascular endothelial cells. Biochemical and biophysical research communications 20030425
Hepatic glutathione and nitric oxide are critical for hepatic insulin-sensitizing substance action. American journal of physiology. Gastrointestinal and liver physiology 20030401
The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity. Archives of biochemistry and biophysics 20030401
Deactivation of norepinephrine by peroxynitrite as a new pathogenesis in the hypotension of septic shock. Anesthesiology 20030401
Nitrergic modulation of hippocampal acetylcholine release is independent of endothelial NO synthase activity. Neurochemical research 20030401
Involvement of nitric oxide donor compounds in the bactericidal activity of human neutrophils in vitro. Journal of medical microbiology 20030401
Endothelium dysfunction in LDL receptor knockout mice: a role for H2O2. British journal of pharmacology 20030401
Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues. British journal of pharmacology 20030401
Protection of insulin-secreting INS-1 cells against oxidative stress through adenoviral-mediated glutathione peroxidase overexpression. Diabetes & metabolism 20030401
Neuroprotective effects of alpha-tocopherol on oxidative stress in rat striatal cultures. European journal of pharmacology 20030328
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice. European journal of pharmacology 20030319
Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery. The Journal of biological chemistry 20030314
Inhibition of actin polymerization by peroxynitrite modulates neutrophil functional responses. Journal of leukocyte biology 20030301
Possible involvement of nitric oxide in the central salt-loading-induced cardiovascular responses in conscious rats. Brain research 20030214
Human sensitive to apoptosis gene protein inhibits peroxynitrite-induced DNA damage. Biochemical and biophysical research communications 20030214
Control of cardiovascular function in the icefish Chionodraco hamatus: involvement of serotonin and nitric oxide. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030201
Gender-related differences in the effects of nitric oxide donors on neuroleptic-induced catalepsy in mice. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20030201
Effects of various nitric oxide-donating drugs on adrenergic tension of human seminal vesicles in vitro. Urology 20030201
Activation of calcium-dependent calmodulin by calcium(II)3(3,5-diisopropylsalicylate)6(H2O)6 decreases thrombin receptor activating peptide-induced P-selectin expression. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030201
Three model systems measure oxidation/nitration damage caused by peroxynitrite. Journal of biosciences 20030201
Inhibition of arginine synthesis by urea: a mechanism for arginine deficiency in renal failure which leads to increased hydroxyl radical generation. Molecular and cellular biochemistry 20030201
Increased endothelin-1 and endothelin receptor expression in myocytes of ischemic and reperfused rat hearts and ventricular myocytes exposed to ischemic conditions and its inhibition by nitric oxide generation. Canadian journal of physiology and pharmacology 20030201
Effect of alpha-tocopherol on the oxidative modification of apolipoprotein E in human very-low-density lipoprotein. Bioscience, biotechnology, and biochemistry 20030201
Fructose-1,6-bisphosphate preserves intracellular glutathione and protects cortical neurons against oxidative stress. Brain research 20030117
Peroxynitrite generated in the rat spinal cord induces oxidation and nitration of proteins: reduction by Mn (III) tetrakis (4-benzoic acid) porphyrin. Journal of neuroscience research 20030115
Nitric oxide and peroxynitrite promote complete disruption of the [4Fe-4S] cluster of recombinant human iron regulatory protein 1. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20030101
Peroxynitrite generated in the rat spinal cord induces apoptotic cell death and activates caspase-3. Neuroscience 20030101
Insights into the mechanism of erythrocyte Na+/K+-ATPase inhibition by nitric oxide and peroxynitrite anion. Journal of applied toxicology : JAT 20030101
Influence of the direct NO-donor SIN-1 on the interaction between platelets and stainless steel stents under dynamic conditions. Clinical hemorheology and microcirculation 20030101
Differential antinociceptive effects of L-arginine and 3-morpholinosydoimine. Proceedings of the Western Pharmacology Society 20030101
The role of nitric oxide in locomotor regulation in mice and its interaction with nitrous oxide. Proceedings of the Western Pharmacology Society 20030101
Participation of the NO-cyclic GMP pathway in rofecoxib-induced antinociception. Proceedings of the Western Pharmacology Society 20030101
A possible defensive mechanism in the basal region of gastric mucosa and the healing of erosions. Clinical hemorheology and microcirculation 20030101
Indirect measurement of nitric oxide production by monitoring nitrate and nitrite using microchip electrophoresis with electrochemical detection. Analytical chemistry 20021215
Exogenous nitric oxide inhibits tumor necrosis factor-alpha- or interleukin-1-beta-induced monocyte chemoattractant protein-1 expression in human mesangial cells. Role of IkappaB-alpha and cyclic GMP. Nephron 20021201
Nitric oxide inhibits irreversibly P815 cell proliferation: involvement of potassium channels. Cell proliferation 20021201
Peroxynitrite activates NF-E2-related factor 2/antioxidant response element through the pathway of phosphatidylinositol 3-kinase: the role of nitric oxide synthase in rat glutathione S-transferase A2 induction. Nitric oxide : biology and chemistry 20021201
The role of reactive oxygen species in action of nitric oxide-donors on stress-induced gastric mucosal lesions. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201
Endothelial secretogogues and deformability of erythrocytes. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201
Comparison of uric acid and ascorbic acid in protection against EAE. Free radical biology & medicine 20021115
Irreversible inactivation of magnesium-dependent neutral sphingomyelinase 1 (NSM1) by peroxynitrite, a nitric oxide-derived oxidant. FEBS letters 20021106
Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling. British journal of pharmacology 20021101
Influence of nitric oxide on the spontaneous activity of globus pallidus neurones in the rat. Journal of neural transmission (Vienna, Austria : 1996) 20021101
Enhanced activity of human IL-10 after nitration in reducing human IL-1 production by stimulated peripheral blood mononuclear cells. Journal of immunology (Baltimore, Md. : 1950) 20021015
Peroxynitrite scavenging activity of sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) isolated from Brassica juncea. Journal of agricultural and food chemistry 20021009
Peroxynitrite triggers a delayed resistance of coronary endothelial cells against ischemia-reperfusion injury. American journal of physiology. Heart and circulatory physiology 20021001
Effects of the nitric oxide donor 3-morpholinosydnonimine (SIN-1) in focal cerebral ischemia dependent on intracellular brain pH. Journal of neurosurgery 20021001
NO- and non-NO-, non-prostanoid-dependent vasodilatation in rat sciatic nerve during maturation and developing experimental diabetic neuropathy. The Journal of physiology 20020915
Ciclopirox prevents peroxynitrite toxicity in astrocytes by maintaining their mitochondrial function: a novel mechanism for cytoprotection by ciclopirox. Neuropharmacology 20020901
NMDA-induced acetylcholine release in mouse striatum: role of NO synthase isoforms. Journal of neurochemistry 20020901
The essential nutrient pyrroloquinoline quinone may act as a neuroprotectant by suppressing peroxynitrite formation. The European journal of neuroscience 20020901
Effects of nitric oxide donors on vascular endothelial growth factor gene induction. Biochemical and biophysical research communications 20020830
Peroxynitrite enhances astrocytic volume-sensitive excitatory amino acid release via a src tyrosine kinase-dependent mechanism. Journal of neurochemistry 20020801
The effects of the nitric oxide donor SIN-1 on ischemia-reperfused cutaneous and myocutaneous flaps. Plastic and reconstructive surgery 20020701
Adenosine and purine nucleosides protect rat primary astrocytes from peroxynitrite-potentiated, glucose deprivation-induced death: preservation of intracellular ATP level. Experimental neurology 20020701
Peroxynitrite enhances the ability of Salmonella dublin to invade T84 monolayers. Shock (Augusta, Ga.) 20020701
Effect of linsidomine on the human radial artery. Clinical science (London, England : 1979) 20020701
Comparison between the influence of the intravenous and intracerebroventricular injection of a nitric oxide donor on adrenocorticotropic hormone release and hypothalamic neuronal activity. Journal of neuroendocrinology 20020701
Reduction of macrophage activation after antioxidant enzymes gene transfer to rat insulinoma INS-1 cells. Immunobiology 20020701
Specificity of antioxidant enzyme inhibition in skeletal muscle to reactive nitrogen species donors. Biochemical and biophysical research communications 20020628
Effects of a nitric oxide donor on behavior and interaction with nitrous oxide in the mouse light/dark exploration test. European journal of pharmacology 20020628
Nitric oxide and peroxynitrite activate the iron regulatory protein-1 of J774A.1 macrophages by direct disassembly of the Fe-S cluster of cytoplasmic aconitase. Biochemistry 20020611
Centrally applied nitric oxide donor elevates plasma corticosterone by activation of the hypothalamic noradrenergic neurons in rats. Brain research 20020607
Effect of SIN-1 in rat ventricular myocytes: interference with beta-adrenergic stimulation. Life sciences 20020607
Identification and in vitro biological activities of hop proanthocyanidins: inhibition of nNOS activity and scavenging of reactive nitrogen species. Journal of agricultural and food chemistry 20020605
Nitric oxide-cGMP-mediated vasoconstriction and effects of acetylcholine in the branchial circulation of the eel. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020601
Effects of sulfur containing amino acids on iron and nitric oxide stimulated catecholamine oxidation. Amino acids 20020601
ATP and nitric oxide modulate a Ca(2+)-activated non-selective cation current in macrovascular endothelial cells. Pflugers Archiv : European journal of physiology 20020601
Induction of SOS response in Salmonella typhimurium TA4107/pSK1002 by peroxynitrite-generating agent, N-morpholino sydnonimine. Mutation research 20020522
Protection of myocytes from hypoxia-reoxygenation injury by nitric oxide is mediated by modulation of transforming growth factor-beta1. Circulation 20020507
Expression of nitric oxide synthases and in vitro migration of eosinophils from allergic rhinitis subjects. European journal of pharmacology 20020503
Prevention of free-radical induced apoptosis by induction of human recombinant Cu, Zn-SOD in pig endothelial cells. Transplant international : official journal of the European Society for Organ Transplantation 20020501
(-)-Deprenyl fails to promote axonal regeneration of retinal ganglion cells in vitro and in vivo. Cell and tissue research 20020501
[Effect of NO on automaticity of rabbit sino-atrial node]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20020501
Formation of peroxynitrite from reaction of nitroxyl anion with molecular oxygen. The Journal of biological chemistry 20020419
Oxidation and nitrosation in the nitrogen monoxide/superoxide system. The Journal of biological chemistry 20020405
Genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells exposed to peroxynitrite generated from SIN-1. Chemical research in toxicology 20020401
Exogenous nitric oxide inhibits VCAM-1 expression in human peritoneal mesothelial cells. Role of cyclic GMP and NF-kappaB. Nephron 20020401
Cross-talk between nitric oxide and superoxide determines ceramide formation and apoptosis in glomerular cells. Kidney international 20020301
Evidence that peroxynitrite affects human osteoblast proliferation and differentiation. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020301
3-Morpholinosydnonimine hydrochloride induces p53-dependent apoptosis in murine primary neural cells: a critical role for p21(ras)-MAPK-p19(ARF) pathway. Nitric oxide : biology and chemistry 20020301
The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain. Nitric oxide : biology and chemistry 20020301
Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species. Chemico-biological interactions 20020220
Peroxynitrite increases iNOS through NF-kappaB and decreases prostacyclin synthase in endothelial cells. American journal of physiology. Cell physiology 20020201
Neuronal formation of free radicals plays a minor role in hypoxic cell death in human NT2-N neurons. Pediatric research 20020201
Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species. Arthritis and rheumatism 20020201
Human renal epithelial cells express iNOS in response to cytokines but not bacteria. Kidney international 20020201
Beneficial effects of nitric oxide inhalation on pulmonary bacterial clearance. Critical care medicine 20020201
Intracavernous administration of SIN-1+VIP in an in vivo rabbit model for erectile function. International journal of impotence research 20020201
[Mechanism of gastric mucosal cell injury induced by reactive oxygen species and nitric oxide]. Nihon rinsho. Japanese journal of clinical medicine 20020201
Cellular mechanisms of nitric oxide-induced relaxation of corporeal smooth muscle in the guinea-pig. The Journal of physiology 20020115
Direct antioxidant properties of creatine. Biochemical and biophysical research communications 20020111
Multiple substrates for paraoxonase-1 during oxidation of phosphatidylcholine by peroxynitrite. Biochemical and biophysical research communications 20020111
Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells. Journal of neural transmission (Vienna, Austria : 1996) 20020101
Protective effects of dihydropyridine Ca-blockers against endothelial cell oxidative injury due to combined nitric oxide and superoxide. Pharmacological research 20020101
Insulin-like growth factor-1 protects peroxynitrite-induced cell death by preventing cytochrome c-induced caspase-3 activation. Journal of cellular biochemistry 20020101
Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020101
The role of peroxynitrite in cyclooxygenase-2 expression of rheumatoid synovium. Clinical and experimental rheumatology 20020101
Vanadate protects human neuroblastoma SH-SY5Y cells against peroxynitrite-induced cell death. Journal of cellular biochemistry 20020101
Induction of thioredoxin reductase gene expression by peroxynitrite in human umbilical vein endothelial cells. Biological chemistry 20020101
The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats. Journal of toxicology. Clinical toxicology 20020101
Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus. Physiological research 20020101
Peroxynitrite generated in the rat spinal cord induces neuron death and neurological deficits. Neuroscience 20020101
Glucocorticoids exacerbate peroxynitrite mediated potentiation of glucose deprivation-induced death of rat primary astrocytes. Brain research 20011227
Dehydroepiandrosterone inhibits the death of immunostimulated rat C6 glioma cells deprived of glucose. Brain research 20011220
Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11beta-hydroxysteroid dehydrogenase. Circulation 20011204
Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha. The EMBO journal 20011203
Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells. American journal of physiology. Cell physiology 20011201
Value of linsidomin in assessing myocardial viability with thallium-201 SPECT. Nuclear medicine communications 20011201
Nitric oxide modulates cerebral blood flow stimulation by acetazolamide in the rat cortex: a laser Doppler scanning study. Neuroscience letters 20011123
In vivo damage of CNS myelin and axons induced by peroxynitrite. Neuroreport 20011116
Killing of lymphoblastic leukemia cells by nitric oxide and taxol: involvement of NF-kappaB activity. Cancer letters 20011108
Role of potassium channels in the relaxation induced by the nitric oxide (NO) donor DEA/NO in the isolated rat basilar artery. Neuroscience letters 20011102
Comparative impacts of glutathione peroxidase-1 gene knockout on oxidative stress induced by reactive oxygen and nitrogen species in mouse hepatocytes. The Biochemical journal 20011101
Microinfusion of a nitric oxide donor in discrete brain regions activates the hypothalamic-pituitary-adrenal axis. Journal of neuroendocrinology 20011101
Effect of selenolipoic acid on peroxynitrite-dependent inactivation of NADPH-cytochrome P450 reductase. Free radical research 20011101
Mutagenicity of nitric oxide-releasing compounds in Escherichia coli: effect of superoxide generation and evidence for two mutagenic mechanisms. Mutation research 20011018
Comparative vasodilation of peroxynitrite and 3-morpholinosydnonimine. Life sciences 20011005
Future of neuroprotection in Parkinson's disease. Parkinsonism & related disorders 20011001
Inhibition of acetylcholine synthesis and tyrosine nitration induced by peroxynitrite are differentially prevented by antioxidants. Molecular pharmacology 20011001
SIN-1-induced cytotoxicity in mixed cortical cell culture: peroxynitrite-dependent and -independent induction of excitotoxic cell death. Journal of neurochemistry 20011001
Effects of nitric oxide on the Ca2+-activated potassium channels in smooth muscle cells of the human corpus cavernosum. Urological research 20011001
Differential modulation of prostaglandin H synthase-2 by nitric oxide-related species in intact cells. Biochemistry 20010925
Effects of nitric oxide and peroxynitrite on endotoxin-induced leukocyte adhesion to endothelium. Journal of cellular physiology 20010901
Peroxynitrite causes endothelial cell monolayer barrier dysfunction. American journal of physiology. Cell physiology 20010901
TBC3711, an ET(A) receptor antagonist, reduces neonatal hypoxia-induced pulmonary hypertension in piglets. Pediatric research 20010901
NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP. British journal of pharmacology 20010901
Genetic augmentation of nitric oxide synthase increases the vascular generation of VEGF. Cardiovascular research 20010901
A study on the role of nitric oxide and iron in 3-morpholino-sydnonimine-induced increases in dopamine release in the striatum of freely moving rats. British journal of pharmacology 20010901
NO donor SIN-1 potentiates monosynaptic reflexes in the cat spinal cord. Neuroreport 20010828
Nitric oxide modulates spontaneous cord dorsum potentials in the cat spinal cord. Neuroscience letters 20010817
Reaction of human myoglobin and peroxynitrite: characterizing biomarkers for myoglobin-derived oxidative stress. Biochemical and biophysical research communications 20010817
Role of nitric oxide in histamine release from human basophils and rat peritoneal mast cells. European journal of pharmacology 20010817
Diversity of endotoxin-induced nitrotyrosine formation in macrophage-endothelium-rich organs. Free radical biology & medicine 20010815
S-nitrosothiols do not induce oxidative stress, contrary to other nitric oxide donors, in cultures of vascular endothelial or smooth muscle cells. European journal of pharmacology 20010803
NF-kappaB, inducible nitric oxide synthase and apoptosis by Helicobacter pylori infection. Free radical biology & medicine 20010801
Mechanism for muscarinic inhibition of I(Ca(L)) is determined by the path for elevating cyclic AMP in cardiac myocytes. Cardiovascular research 20010801
Induction of cyclo-oxygenase-2 in human endothelial cells by SIN-1 in the absence of prostaglandin production. British journal of pharmacology 20010801
Actions of NO donors and endogenous nitrergic transmitter on the longitudinal muscle of rat ileum in vitro: mechanisms involved. Life sciences 20010727
Apolipoprotein A-I promotes the formation of phosphatidylcholine core aldehydes that are hydrolyzed by paraoxonase (PON-1) during high density lipoprotein oxidation with a peroxynitrite donor. The Journal of biological chemistry 20010706
Anti-adrenergic effects of nitric oxide donor SIN-1 in rat cardiac myocytes. American journal of physiology. Cell physiology 20010701
Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization. British journal of pharmacology 20010701
Contractility of late pregnant rat myometrium is refractory to activation of soluble but not particulate guanylate cyclase. American journal of obstetrics and gynecology 20010701
Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution. Biochemistry 20010626
In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation. Blood 20010601
Oxidative stress promotes the development of transformation: involvement of a potent mutagenic lipid peroxidation product, acrolein. Carcinogenesis 20010601
Immunostimulation of rat primary astrocytes decreases intracellular ATP level. Brain research 20010601
Antiapoptotic properties of rasagiline, N-propargylamine-1(R)-aminoindan, and its optical (S)-isomer, TV1022. Annals of the New York Academy of Sciences 20010601
Classes of thiols that influence the activity of the skeletal muscle calcium release channel. The Journal of biological chemistry 20010511
Nitric oxide reduces energy supply by direct action on the respiratory chain in isolated cardiomyocytes. American journal of physiology. Heart and circulatory physiology 20010501
Effects of nitric oxide on normal and ischemic cochlea of the guinea pig. Experimental neurology 20010501
SIN-1, a nitric oxide donor, ameliorates experimental allergic encephalomyelitis in Lewis rats in the incipient phase: the importance of the time window. Journal of immunology (Baltimore, Md. : 1950) 20010501
A redox-based mechanism for the contractile and relaxing effects of NO in the guinea-pig gall bladder. The Journal of physiology 20010501
Nitric oxide modulates cardiac performance in the heart of Anguilla anguilla. The Journal of experimental biology 20010501
Peroxynitrite inhibits inducible (type 2) nitric oxide synthase in murine lung epithelial cells in vitro. Free radical biology & medicine 20010501
Hepatocellular oxidative DNA injury induced by macrophage-derived nitric oxide. Free radical biology & medicine 20010501
Influence of endothelium in dose-dependent inhibition and potentiation by isoniazid of isosorbide dinitrate relaxation of rat aorta. Journal of cardiovascular pharmacology 20010501
Nitrogen dioxide induces death in lung epithelial cells in a density-dependent manner. American journal of respiratory cell and molecular biology 20010501
Danchunhwan water extract prevents apoptotic death by peroxynitrite and nitric oxide in human dopaminergic neuroblastoma SH-SY5Y cells. Immunopharmacology and immunotoxicology 20010501
17 beta-Estradiol inhibits carotid sinus baroreceptor activity in anesthetized male rats. Acta pharmacologica Sinica 20010501
The dual effect of a nitric oxide donor in nociception. Brain research 20010406
Protective effects of morphine in peroxynitrite-induced apoptosis of primary rat neonatal astrocytes: potential involvement of G protein and phosphatidylinositol 3-kinase (PI3 kinase). Biochemical pharmacology 20010401
Evidence that nitric oxide-induced synthesis of cGMP occurs in a paracrine but not an autocrine fashion and that the site of its release can be regulated: studies in dorsal root ganglia in vivo and in vitro. Nitric oxide : biology and chemistry 20010401
Effects of endothelin-1 and nitric oxide on proliferation of cultured guinea pig bronchial smooth muscle cells. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010401
Two different NO-dependent mechanisms account for the low virulence of a non-mycelial morphological mutant of Candida albicans. Medical microbiology and immunology 20010401
SIN-1-induced DNA damage in isolated human peripheral blood lymphocytes as assessed by single cell gel electrophoresis (comet assay). Free radical biology & medicine 20010315
Characterization of peroxynitrite-oxidized low density lipoprotein binding to human CD36. Atherosclerosis 20010301
Superoxide dismutase activity in organotypic midbrain-striatum co-cultures is associated with resistance of dopaminergic neurons to excitotoxicity. Journal of neurochemistry 20010301
Cytotoxic effects of peroxynitrite, polymorphonuclear neutrophils, free-radical scavengers, inhibitors of myeloperoxidase, and inhibitors of nitric oxide synthase on bovine mammary secretory epithelial cells. American journal of veterinary research 20010301
Inhibition of nitric oxide synthase activity reduces liver injury in murine schistosomiasis. Parasitology 20010301
Rat germinal cells require PARP for repair of DNA damage induced by gamma-irradiation and H2O2 treatment. European journal of cell biology 20010301
Regulation of neuronal growth cone filopodia by nitric oxide depends on soluble guanylyl cyclase. Journal of neurobiology 20010215
NO donors inhibit Leishmania infantum cysteine proteinase activity. Biochimica et biophysica acta 20010209
Role of nitric oxide in the synthesis of guanidinosuccinic acid, an activator of the N-methyl-D-aspartate receptor. Kidney international. Supplement 20010201
Effects of endogenous nitric oxide in activation of group IV muscle afferents. Muscle & nerve 20010201
Chemical evaluation of compounds as nitric oxide or peroxynitrite donors using the reactions with serotonin. Free radical research 20010201
Peroxynitrite induces GADD34, 45, and 153 VIA p38 MAPK in human neuroblastoma SH-SY5Y cells. Free radical biology & medicine 20010115
Augmented death in immunostimulated astrocytes deprived of glucose: inhibition by an iron porphyrin FeTMPyP. Journal of neuroimmunology 20010101
Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro. Free radical biology & medicine 20010101
Inhibition of nerve growth factor signaling by peroxynitrite. Journal of neuroscience research 20010101
Mechanisms of nitric oxide-induced cytotoxicity in normal human hepatocytes. Environmental and molecular mutagenesis 20010101
Nitric oxide in the afferent synaptic transmission of the axolotl vestibular system. Neuroscience 20010101
Response of neonatal platelets to nitric oxide in vitro. Intensive care medicine 20010101
Light and scanning-electron microscopic examination of coronary stents in a perfusion-model. Effects of an NO-donor/quantitative analysis. Clinical hemorheology and microcirculation 20010101
Nonvasomotor influence of sodium nitroprusside on arteriolar remote response to methacholine. Journal of vascular research 20010101
Taurine is a weak scavenger of peroxynitrite and does not attenuate sodium nitroprusside toxicity to cells in culture. Amino acids 20010101
Phenanthrenequinone disrupts progesterone production in rat luteal cells. Reproductive toxicology (Elmsford, N.Y.) 20010101
Shear stress-induced nitric oxide release triggers the liver regeneration cascade. Nitric oxide : biology and chemistry 20010101
Involvement of PKC and NF-kappaB in nitric oxide induced apoptosis in human coronary artery smooth muscle cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101
Nitric oxide synthase inhibition decreases output of hepatic insulin sensitizing substance (HISS), which is reversed by SIN-1 but not by nitroprusside. Proceedings of the Western Pharmacology Society 20010101
Actions of S-nitroso N-acetyl penicillamine and 3-morpholinosydonimine may involve disparate signaling pathways in myometrial smooth muscle. Proceedings of the Western Pharmacology Society 20010101
The effects of SIN-1 on contractility and cyclic GMP levels in the pregnant mouse uterus. Proceedings of the Western Pharmacology Society 20010101
[Effects of nitric oxide donor SIN-1 on calcium transport in rat cardiac sarcoplasmic reticulum]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101
Nitric oxide stimulates ACTH secretion and the transcription of the genes encoding for NGFI-B, corticotropin-releasing factor, corticotropin-releasing factor receptor type 1, and vasopressin in the hypothalamus of the intact rat. The Journal of neuroscience : the official journal of the Society for Neuroscience 19990901
Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors. Biochemical pharmacology 19990715
Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide. Cell death and differentiation 19981001
Peroxynitrite modulates MnSOD gene expression in lung epithelial cells. Free radical biology & medicine 19980901
Effect of intracerebroventricular and intravenous administration of nitric oxide donors on blood pressure and heart rate in anaesthetized rats. British journal of pharmacology 19961201
Mediation by prostaglandins of the nitric oxide-induced neurogenic vasodilatation in rat skin. British journal of pharmacology 19951101
Prostaglandin E1 and the nitric oxide donor linsidomine for erectile failure: a diagnostic comparative study of 40 patients. The Journal of urology 19930501
Inhibitors of calmodulin impair the constitutive but not the inducible nitric oxide synthase activity in the rat aorta. The Journal of pharmacology and experimental therapeutics 19920501
Torsades de pointes after intracoronary papaverine. European heart journal 19910201
Nitroglycerin-resistant coronary spasm treated with intracoronary linsidomine chlorhydrate (SIN-1). European heart journal 19900501
Properties