Name: Name:Hth-01-015
Brand: Angene
SKU: AG001SE7
Rating: 90 (10 reviews)

Hth-01-015

CAS No.:

1613724-42-7

Catalog Number:

AG001SE7

Molecular Formula:

C26H28N8O

Molecular Weight:

468.5535

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

1mg

≥95%

1 week

United States

$139

- +

5mg

≥95%

1 week

United States

$180

- +

10mg

99%

1 week

United States

$251

- +

50mg

99%

1 week

United States

$654

- +

100mg

99%

1 week

United States

$793

- +

Product Description

Catalog Number:

AG001SE7

Chemical Name:

Hth-01-015

CAS Number:

1613724-42-7

Molecular Formula:

C26H28N8O

Molecular Weight:

468.5535

MDL Number:

MFCD28167816

IUPAC Name:

2,7,9-trimethyl-5-[(1-piperidin-4-ylpyrazol-4-yl)amino]-2,4,6,9-tetrazatetracyclo[9.8.0.03,8.013,18]nonadeca-1(19),3,5,7,11,13,15,17-octaen-10-one

InChI:

InChI=1S/C26H28N8O/c1-16-23-24(31-26(29-16)30-19-14-28-34(15-19)20-8-10-27-11-9-20)32(2)22-13-18-7-5-4-6-17(18)12-21(22)25(35)33(23)3/h4-7,12-15,20,27H,8-11H2,1-3H3,(H,29,30,31)

InChI Key:

CHSDJDLAKKAWCI-UHFFFAOYSA-N

SMILES:

Cc1nc(Nc2cnn(c2)C2CCNCC2)nc2c1n(C)c(=O)c1c(n2C)cc2c(c1)cccc2

Properties

Complexity:

762

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

468.239g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

468.565g/mol

Monoisotopic Mass:

468.239g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

91.2A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

3.2

Literature

Title	Journal
Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase.	The Biochemical journal 20140715
Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases.	The Biochemical journal 20140101

Properties