Pregna-1,4-diene-3,20-dione, 16,17-[[(R)-cyclohexylmethylene]bis(oxy)]-11,21-dihydroxy-, (11β,16α)-
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Formoterol synergy with des-ciclesonide inhibits IL-4 expression in IgE/antigen-induced mast cells by inhibiting JNK activation. | European journal of pharmacology 20150815 |
Ciclesonide--a novel corticosteroid for the management of asthma. | Current clinical pharmacology 20120501 |
Rapid nongenomic actions of inhaled corticosteroids on long-acting β(2)-agonist transport in the airway. | Pulmonary pharmacology & therapeutics 20111201 |
Simultaneous determination of ciclesonide and its active metabolite desisobutyryl-ciclesonide in human plasma by LC-APCI-MS/MS: application to pharmacokinetic study in healthy Chinese volunteers. | Journal of pharmaceutical and biomedical analysis 20110428 |
Population pharmacokinetics and pharmacodynamics of inhaled ciclesonide and fluticasone propionate in patients with persistent asthma. | Journal of clinical pharmacology 20101001 |
Pharmacokinetics of ciclesonide and desisobutyryl ciclesonide after administration via aqueous nasal spray or hydrofluoroalkane nasal aerosol compared with orally inhaled ciclesonide: an open-label, single-dose, three-period crossover study in healthy volunteers. | Clinical therapeutics 20091201 |
Clinical pharmacokinetic and pharmacodynamic profile of inhaled ciclesonide. | Clinical pharmacokinetics 20090101 |
Effect of coadministered ketoconazole, a strong cytochrome P450 3A4 enzyme inhibitor, on the pharmacokinetics of ciclesonide and its active metabolite desisobutyryl-ciclesonide. | Clinical pharmacokinetics 20080101 |
Modulation of human lung fibroblast functions by ciclesonide: evidence for its conversion into the active metabolite desisobutyryl-ciclesonide. | Immunology letters 20070915 |
The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue. | Biochemical pharmacology 20070515 |
In vitro metabolism of ciclesonide in human nasal epithelial cells. | Biopharmaceutics & drug disposition 20070101 |
Uptake and metabolism of ciclesonide and retention of desisobutyryl-ciclesonide for up to 24 hours in rabbit nasal mucosa. | BMC pharmacology 20070101 |
In Vitro metabolism of ciclesonide in human lung and liver precision-cut tissue slices. | Biopharmaceutics & drug disposition 20060501 |
Safety, tolerability, and exposure of ciclesonide nasal spray in healthy and asymptomatic subjects with seasonal allergic rhinitis. | Journal of clinical pharmacology 20060401 |
High lung deposition of 99mTc-labeled ciclesonide administered via HFA-MDI to patients with asthma. | Respiratory medicine 20060301 |
Modulation of p-glycoprotein and breast cancer resistance protein by some prescribed corticosteroids. | European journal of pharmacology 20060215 |
Pharmacokinetic disposition of inhaled ciclesonide and its metabolite desisobutyryl-ciclesonide in healthy subjects and patients with asthma are similar. | International journal of clinical pharmacology and therapeutics 20060101 |
Ciclesonide disposition and metabolism: pharmacokinetics, metabolism, and excretion in the mouse, rat, rabbit, and dog. | American journal of therapeutics 20060101 |
Preclinical profile of ciclesonide, a novel corticosteroid for the treatment of asthma. | The Journal of pharmacology and experimental therapeutics 20050801 |
Lower oropharyngeal deposition of inhaled ciclesonide via hydrofluoroalkane metered-dose inhaler compared with budesonide via chlorofluorocarbon metered-dose inhaler in healthy subjects. | European journal of clinical pharmacology 20050501 |
Comparison of the oropharyngeal deposition of inhaled ciclesonide and fluticasone propionate in patients with asthma. | Journal of clinical pharmacology 20050201 |
Protein binding and its potential for eliciting minimal systemic side effects with a novel inhaled corticosteroid, ciclesonide. | American journal of therapeutics 20050101 |
Model-based covariate pharmacokinetic analysis and lack of cortisol suppression by the new inhaled corticosteroid ciclesonide using a novel cortisol release model. | American journal of therapeutics 20050101 |
Ciclesonide. | Drugs 20040101 |