4-Iodo-3-nitrobenzamide
Title | Journal |
---|---|
Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle. | Cell metabolism 20140603 |
Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
Iniparib plus paclitaxel and carboplatin as initial treatment of advanced or recurrent uterine carcinosarcoma: a Gynecologic Oncology Group Study. | Gynecologic oncology 20120901 |
Neoadjuvant treatments for triple-negative breast cancer (TNBC). | Annals of oncology : official journal of the European Society for Medical Oncology 20120801 |
Current and emerging targeted therapies for metastatic breast cancer. | Cancer 20120615 |
Dissecting the heterogeneity of triple-negative breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120520 |
Re: potential pitfalls of crossover and thoughts on iniparib in triple-negative breast cancer. | Journal of the National Cancer Institute 20120502 |
Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides. | Chemical communications (Cambridge, England) 20120425 |
[PARP inhibitors and breast cancer: update and perspectives]. | Bulletin du cancer 20120401 |
Drug candidates derailed in case of mistaken identity. | Nature 20120328 |
Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120315 |
Present status and problems on molecular targeted therapy of cancer. | Cancer research and treatment : official journal of Korean Cancer Association 20120301 |
Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120115 |
Basal breast cancer: a complex and deadly molecular subtype. | Current molecular medicine 20120101 |
Ovarian cancer: opportunity for targeted therapy. | Journal of oncology 20120101 |
BRCAness profile of sporadic ovarian cancer predicts disease recurrence. | PloS one 20120101 |
Molecular basis of triple negative breast cancer and implications for therapy. | International journal of breast cancer 20120101 |
Current Status of Poly(ADP-ribose) Polymerase Inhibitors as Novel Therapeutic Agents for Triple-Negative Breast Cancer. | International journal of breast cancer 20120101 |
Major clinical research advances in gynecologic cancer in 2011. | Journal of gynecologic oncology 20120101 |
Advances in using PARP inhibitors to treat cancer. | BMC medicine 20120101 |
Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways. | Journal of oncology 20120101 |
Metastasis of neuroendocrine tumors are characterized by increased cell proliferation and reduced expression of the ATM gene. | PloS one 20120101 |
Advancements in the Treatment of Metastatic Breast Cancer (MBC): The Role of Ixabepilone. | Journal of oncology 20120101 |
The first European interdisciplinary ewing sarcoma research summit. | Frontiers in oncology 20120101 |
Potential pitfalls of crossover and thoughts on iniparib in triple-negative breast cancer. | Journal of the National Cancer Institute 20111207 |
The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy. | Therapeutic advances in medical oncology 20111101 |
Response of subtype-specific human breast cancer-derived cells to poly(ADP-ribose) polymerase and checkpoint kinase 1 inhibition. | Cancer science 20111001 |
PARP inhibitors--current status and the walk towards early breast cancer. | Breast (Edinburgh, Scotland) 20111001 |
DNA-damaging therapies emerging as possible triple-negative breast cancer therapies. | Oncology (Williston Park, N.Y.) 20111001 |
PARP inhibitors: its role in treatment of cancer. | Chinese journal of cancer 20110701 |
Novel agents and future directions for refractory breast cancer. | Seminars in oncology 20110601 |
Iniparib in metastatic triple-negative breast cancer. | The New England journal of medicine 20110505 |
Few positives for triple-negative breast cancer. | Journal of the National Cancer Institute 20110406 |
Evidence for the efficacy of Iniparib, a PARP-1 inhibitor, in BRCA2-associated pancreatic cancer. | Anticancer research 20110401 |
Triple negative breast cancer: unmet medical needs. | Breast cancer research and treatment 20110201 |
Iniparib plus chemotherapy in metastatic triple-negative breast cancer. | The New England journal of medicine 20110120 |
PARP and cancer--if it's broke, don't fix it. | The New England journal of medicine 20110120 |
PARP inhibitors in oncology: a new synthetic lethal approach to cancer therapy. | Acta clinica Belgica 20110101 |
Promising molecular targeted therapies in breast cancer. | Indian journal of pharmacology 20110101 |
Targeted treatment of recurrent platinum-resistant ovarian cancer: current and emerging therapies. | Cancer management and research 20110101 |
Enhanced sensitivity to cisplatin and gemcitabine in Brca1-deficient murine mammary epithelial cells. | BMC pharmacology 20110101 |
Drug therapy for hereditary cancers. | Hereditary cancer in clinical practice 20110101 |
Management options in triple-negative breast cancer. | Breast cancer : basic and clinical research 20110101 |
Poly(ADP-ribose) polymerase inhibition: a new direction for BRCA and triple-negative breast cancer? | Breast cancer research : BCR 20110101 |
Tips and tricks in triple-negative breast cancer: how to manage patients in real-life practice? | Ecancermedicalscience 20110101 |
Triple-negative breast cancer: adjuvant therapeutic options. | Chemotherapy research and practice 20110101 |
[PARP inhibitors to treat triple negative breast cancer]. | Gan to kagaku ryoho. Cancer & chemotherapy 20101201 |
Iniparib, a PARP1 inhibitor for the potential treatment of cancer, including triple-negative breast cancer. | IDrugs : the investigational drugs journal 20100901 |
Small-molecule PARP modulators--current status and future therapeutic potential. | Current opinion in drug discovery & development 20100901 |
Beyond PARP inhibitors: agents in pipelines target DNA repair mechanisms. | Journal of the National Cancer Institute 20100804 |
Treatment options for patients with triple-negative breast cancer. | Journal of hematology & oncology 20100101 |
Directed therapy of subtypes of triple-negative breast cancer. | The oncologist 20100101 |
Enzymatic mechanism of the tumoricidal action of 4-iodo-3-nitrobenzamide. | Molecular medicine reports 20090101 |
Anti-cancer action of 4-iodo-3-nitrobenzamide in combination with buthionine sulfoximine: inactivation of poly(ADP-ribose) polymerase and tumor glycolysis and the appearance of a poly(ADP-ribose) polymerase protease. | Biochemical pharmacology 20020201 |
Potential chemotherapeutic activity of 4-iodo-3-nitrobenzamide. Metabolic reduction to the 3-nitroso derivative and induction of cell death in tumor cells in culture. | Biochemical pharmacology 19950825 |