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Isrib

CAS No.:
1597403-47-8
Catalog Number:
AG001RD9
Molecular Formula:
C22H24Cl2N2O4
Molecular Weight:
451.3430
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥95%
1 week
United States
$147
- +
10mg
≥95%
1 week
United States
$229
- +
25mg
≥95%
1 week
United States
$464
- +
50mg
99%
1 week
United States
$657
- +
100mg
99%
1 week
United States
$1140
- +
Product Description
Catalog Number:
AG001RD9
Chemical Name:
Isrib
CAS Number:
1597403-47-8
Molecular Formula:
C22H24Cl2N2O4
Molecular Weight:
451.3430
MDL Number:
MFCD27952932
IUPAC Name:
2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide
InChI:
InChI=1S/C22H24Cl2N2O4/c23-15-1-9-19(10-2-15)29-13-21(27)25-17-5-7-18(8-6-17)26-22(28)14-30-20-11-3-16(24)4-12-20/h1-4,9-12,17-18H,5-8,13-14H2,(H,25,27)(H,26,28)
InChI Key:
HJGMCDHQPXTGAV-UHFFFAOYSA-N
SMILES:
O=C(N[C@@H]1CC[C@H](CC1)NC(=O)COc1ccc(cc1)Cl)COc1ccc(cc1)Cl
Properties
Complexity:
493  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
450.111g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
451.344g/mol
Monoisotopic Mass:
450.111g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
76.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.8  
Literature
Title Journal
Time-resolved analysis of amino acid stress identifies eIF2 phosphorylation as necessary to inhibit mTORC1 activity in liver. The Journal of biological chemistry 20180406
ATF4 regulates arsenic trioxide-mediated NADPH oxidase, ER-mitochondrial crosstalk and apoptosis. Archives of biochemistry and biophysics 20161101
Properties