Name: Name:1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester
Brand: Angene
SKU: AG001RB2
Rating: 90 (10 reviews)

1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester

CAS No.:

15966-93-5

Catalog Number:

AG001RB2

Molecular Formula:

C18H18N2O3

Molecular Weight:

310.3471

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

1mg

≥95%

1 week

United States

$194

- +

5mg

≥95%

1 week

United States

$668

- +

10mg

≥95%

1 week

United States

$1126

- +

25mg

98%

1 week

United States

$2807

- +

Product Description

Catalog Number:

AG001RB2

Chemical Name:

1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester

CAS Number:

15966-93-5

Molecular Formula:

C18H18N2O3

Molecular Weight:

310.3471

MDL Number:

MFCD04974538

IUPAC Name:

ethyl 2,4-dimethyl-5-[(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrole-3-carboxylate

InChI:

InChI=1S/C18H18N2O3/c1-4-23-18(22)16-10(2)15(19-11(16)3)9-13-12-7-5-6-8-14(12)20-17(13)21/h5-9,19H,4H2,1-3H3,(H,20,21)

InChI Key:

PMUJUSJUVIXDQC-UHFFFAOYSA-N

SMILES:

CCOC(=O)c1c(C)[nH]c(c1C)C=C1C(=O)Nc2c1cccc2

Properties

Complexity:

516

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

310.132g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

310.353g/mol

Monoisotopic Mass:

310.132g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

71.2A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

2.7

Literature

Title	Journal
t(8;21) acute myeloid leukaemia cells are dependent on vascular endothelial growth factor (VEGF)/VEGF receptor type2 pathway and phosphorylation of Akt.	British journal of haematology 20061201
Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases.	Journal of medicinal chemistry 19980702