Home Other Building Blocks 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetamide

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetamide

CAS No.:
157599-02-5
Catalog Number:
AG001PIX
Molecular Formula:
C16H32N8O4
Molecular Weight:
400.4765
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
Product Description
Catalog Number:
AG001PIX
Chemical Name:
1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetamide
CAS Number:
157599-02-5
Molecular Formula:
C16H32N8O4
Molecular Weight:
400.4765
MDL Number:
MFCD09263318
IUPAC Name:
2-[4,7,10-tris(2-amino-2-oxoethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetamide
InChI:
InChI=1S/C16H32N8O4/c17-13(25)9-21-1-2-22(10-14(18)26)5-6-24(12-16(20)28)8-7-23(4-3-21)11-15(19)27/h1-12H2,(H2,17,25)(H2,18,26)(H2,19,27)(H2,20,28)
InChI Key:
FQIHLPGWBOBPSG-UHFFFAOYSA-N
SMILES:
NC(=O)CN1CCN(CCN(CCN(CC1)CC(=O)N)CC(=O)N)CC(=O)N
Properties
Complexity:
447  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
400.255g/mol
Formal Charge:
0
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
400.484g/mol
Monoisotopic Mass:
400.255g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
185A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-4.1  
Literature
Title Journal
Iron(II) complexes containing octadentate tetraazamacrocycles as paraCEST magnetic resonance imaging contrast agents. Inorganic chemistry 20120716
DOTAM-type ligands possessing arginine pendant groups for use in PARACEST MRI. Contrast media & molecular imaging 20120101
Gd(III) chelates as NMR probes of protein-protein interactions. Case study: rubredoxin and cytochrome c3. Inorganic chemistry 20111107
Contrast agents possessing high temperature sensitivity. Chemical communications (Cambridge, England) 20110828
NMR of insensitive nuclei enhanced by dynamic nuclear polarization. Chimia 20110101
Synthesis of MRI contrast agents derived from DOTAM-Gly-L-Phe-OH incorporating a disulfide bridge: conjugation to a cell penetrating peptide and preparation of a dimeric agent. Bioorganic & medicinal chemistry letters 20100915
Selective detection of phosphotyrosine in the presence of various phosphate-containing biomolecules with the aid of a terbium(III) complex. Chembiochem : a European journal of chemical biology 20090720
A new synthesis of cystamine modified Eu3+ DOTAM-Gly-Phe-OH: a conjugation ready temperature sensitive MRI contrast agent. Organic & biomolecular chemistry 20081007
The thulium complex of 1,4,7,10-tetrakis{[N-(1H-imidazol-2-yl)carbamoyl]methyl}-1,4,7,10-tetraazacyclododecane (dotami) as a ParaCEST contrast agent. Chemistry & biodiversity 20080801
Analogs of Eu3+ DOTAM-Gly-Phe-OH and Tm3+ DOTAM-Gly-Lys-OH: synthesis and magnetic properties of potential PARACEST MRI contrast agents. Bioorganic & medicinal chemistry 20080601
On the sensitivity of f electrons to their chemical environment. Journal of the American Chemical Society 20080220
A sensitive PARACEST contrast agent for temperature MRI: Eu3+-DOTAM-glycine (Gly)-phenylalanine (Phe). Magnetic resonance in medicine 20080201
A robust and convergent synthesis of dipeptide-DOTAM conjugates as chelators for lanthanide ions: new PARACEST MRI agents. Bioconjugate chemistry 20070101
Non-cytotoxic, bifunctional EuIII and TbIII luminescent macrocyclic complexes for luminescence resonant energy-transfer experiments. Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
Structural characterisation of a diprotonated ligand lanthanide complex--a key intermediate in lanthanide ion association and complex dissociation pathways. Dalton transactions (Cambridge, England : 2003) 20060721
Structural effects of the lone pair on lead(II), and parallels with the coordination geometry of mercury(II). Does the lone pair on lead(II) form H-bonds? Structures of the lead(II) and mercury(II) complexes of the pendant-donor macrocycle DOTAM (1,4,7,10-tetrakis(carbamoylmethyl)-1,4,7,10-tetraazacyclododecane). Inorganic chemistry 20040503
Properties