L-Norleucine, 6-diazo-5-oxo-
| Title | Journal |
|---|---|
| Preventing Allograft Rejection by Targeting Immune Metabolism. | Cell reports 20151027 |
| Computational and experimental analysis identified 6-diazo-5-oxonorleucine as a potential agent for treating infection by Plasmodium falciparum. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20131201 |
| Mycobacterium tuberculosis prokaryotic ubiquitin-like protein-deconjugating enzyme is an unusual aspartate amidase. | The Journal of biological chemistry 20121026 |
| Glutamate released by Japanese encephalitis virus-infected microglia involves TNF-α signaling and contributes to neuronal death. | Glia 20120301 |
| Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes. | International journal of vascular medicine 20120101 |
| The hypothalamus mediates the effect of cerebellar fastigial nuclear glutamatergic neurons on humoral immunity. | Neuro endocrinology letters 20120101 |
| A simple method for measuring intracellular activities of glutamine synthetase and glutaminase in glial cells. | American journal of physiology. Cell physiology 20111001 |
| Glutamine analogs promote cytoophidium assembly in human and Drosophila cells. | Journal of genetics and genomics = Yi chuan xue bao 20110920 |
| Metabolism and brain cancer. | Clinics (Sao Paulo, Brazil) 20110601 |
| Evidence that chromium modulates cellular cholesterol homeostasis and ABCA1 functionality impaired by hyperinsulinemia--brief report. | Arteriosclerosis, thrombosis, and vascular biology 20110501 |
| A practical method for cell-free protein synthesis to avoid stable isotope scrambling and dilution. | Analytical biochemistry 20110415 |
| Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells. | Nature chemical biology 20110301 |
| Hyperammonemia increases the expression and activity of the glutamine/arginine transporter y+ LAT2 in rat cerebral cortex: implications for the nitric oxide/cGMP pathway. | Neurochemistry international 20110201 |
| Synergistic action of hypoosmolarity and glutamine in inducing acute swelling of retinal glial (Müller) cells. | Glia 20110201 |
| Increased expression of cystine/glutamate antiporter in multiple sclerosis. | Journal of neuroinflammation 20110101 |
| Predicting selective drug targets in cancer through metabolic networks. | Molecular systems biology 20110101 |
| Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis. | PloS one 20110101 |
| Induction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cells. | PloS one 20110101 |
| Glutamine targeting inhibits systemic metastasis in the VM-M3 murine tumor model. | International journal of cancer 20101115 |
| Partial purification and characterization of glutaminase from Lactobacillus reuteri KCTC3594. | Applied biochemistry and biotechnology 20100901 |
| The metabolic enzyme CTP synthase forms cytoskeletal filaments. | Nature cell biology 20100801 |
| O-GlcNAc Modification: Friend or Foe in Diabetic Cardiovascular Disease. | Korean diabetes journal 20100801 |
| Characteristic increase in nucleocytoplasmic protein glycosylation by O-GlcNAc in 3T3-L1 adipocyte differentiation. | Biochemical and biophysical research communications 20100730 |
| Peripheral inhibition of glutaminase reduces carrageenan-induced Fos expression in the superficial dorsal horn of the rat. | Neuroscience letters 20100326 |
| Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells. | American journal of physiology. Endocrinology and metabolism 20100301 |
| Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux. | American journal of physiology. Endocrinology and metabolism 20100201 |
| Peritoneal adhesion and angiogenesis in ovarian carcinoma are inversely regulated by hyaluronan: the role of gonadotropins. | Neoplasia (New York, N.Y.) 20100101 |
| Cancer as a metabolic disease. | Nutrition & metabolism 20100101 |
| Cell-cycle inhibition by Helicobacter pylori L-asparaginase. | PloS one 20100101 |
| O-glycosylation regulates ubiquitination and degradation of the anti-inflammatory protein A20 to accelerate atherosclerosis in diabetic ApoE-null mice. | PloS one 20100101 |
| High glucose induces transactivation of the alpha2-HS glycoprotein gene through the ERK1/2 signaling pathway. | Journal of atherosclerosis and thrombosis 20090801 |
| Glutamine inhibits ammonia-induced accumulation of cGMP in rat striatum limiting arginine supply for NO synthesis. | Neurobiology of disease 20090701 |
| L-Glutamine-induced apoptosis in microglia is mediated by mitochondrial dysfunction. | The European journal of neuroscience 20090701 |
| Blockade of glutamate release from microglia attenuates experimental autoimmune encephalomyelitis in mice. | The Tohoku journal of experimental medicine 20090201 |
| Blockade of microglial glutamate release protects against ischemic brain injury. | Experimental neurology 20081101 |
| Influence of hyaluronan accumulation during cumulus expansion on in vitro porcine oocyte maturation. | Zygote (Cambridge, England) 20081101 |
| Synthesis of potent water-soluble tissue transglutaminase inhibitors. | Bioorganic & medicinal chemistry letters 20081015 |
| Premature senescence of human endothelial cells induced by inhibition of glutaminase. | Biogerontology 20080801 |
| Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis. | Biochemistry 20080527 |
| Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors. | Life sciences 20080523 |
| Which mechanisms are involved in taurine-dependent granulocytic immune response or amino- and alpha-keto acid homeostasis? | Amino acids 20080201 |
| Glutamine as a precursor for transmitter glutamate, aspartate and GABA in the cerebellum: a role for phosphate-activated glutaminase. | Journal of neurochemistry 20080201 |
| [Isolation of Pseudomonas aurantiaca strains capable of overproduction of phenazine antibiotics]. | Mikrobiologiia 20080101 |
| Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway. | Journal of neuroinflammation 20080101 |
| Transglutaminase 2 undergoes a large conformational change upon activation. | PLoS biology 20071201 |
| A tertiary twist to the transglutaminase tale. | PLoS biology 20071201 |
| Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. | Chemistry & biology 20071001 |
| Perturbations in factor XIII resulting from activation and inhibition examined by solution based methods and detected by MALDI-TOF MS. | Biochemistry 20070904 |
| Pathways involved in alanyl-glutamine-induced changes in neutrophil amino- and alpha-keto acid homeostasis or immunocompetence. | Amino acids 20070901 |
| O-linked N-acetylglucosaminyltransferase inhibition prevents G2/M transition in Xenopus laevis oocytes. | The Journal of biological chemistry 20070427 |
| Influence of hyaluronic acid synthesis and cumulus mucification on bovine oocyte in vitro maturation, fertilisation and embryo development. | Reproduction, fertility, and development 20070101 |
| y+ LAT-1 mediates transport of the potent and selective iNOS inhibitor, GW274150, in control J774 macrophages. | Amino acids 20060901 |
| O-linked N-acetylglucosamine suppresses thermal aggregation of Sp1. | FEBS letters 20060821 |
| Heat induction of heat shock protein 25 requires cellular glutamine in intestinal epithelial cells. | American journal of physiology. Cell physiology 20060801 |
| Glutamine binding opens the ammonia channel and activates glucosamine-6P synthase. | The Journal of biological chemistry 20060217 |
| Glutamine in the mechanism of ammonia-induced astrocyte swelling. | Neurochemistry international 20060101 |
| Glucose-containing peritoneal dialysis fluids regulate leptin secretion from 3T3-L1 adipocytes. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050701 |
| Differential response of glutamine in cultured neurons and astrocytes. | Journal of neuroscience research 20050101 |
| Modulation of tumor induced angiogenesis in Ehrlich ascites tumor. | Journal of experimental & clinical cancer research : CR 20041201 |
| L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer. | American journal of physiology. Gastrointestinal and liver physiology 20040901 |
| Ammonia neurotoxicity and the mitochondrial permeability transition. | Journal of bioenergetics and biomembranes 20040801 |
| Androgen secretion by Rcho-1 cells is independent of extracellular glutamate concentration. | Placenta 20040701 |
| Glutamine-induced free radical production in cultured astrocytes. | Glia 20040501 |
| A signaling role of glutamine in insulin secretion. | The Journal of biological chemistry 20040402 |
| Retinal function loss after monocarboxylate transport inhibition. | Investigative ophthalmology & visual science 20040201 |
| Characterization of the products of the genes SNO1 and SNZ1 involved in pyridoxine synthesis in Saccharomyces cerevisiae. | European journal of biochemistry 20040201 |
| Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia. | Journal of neurochemistry 20040101 |
| Glutamine stimulates argininosuccinate synthetase gene expression through cytosolic O-glycosylation of Sp1 in Caco-2 cells. | The Journal of biological chemistry 20031226 |
| High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells. | Endocrinology 20031001 |
| Role of acetyl-L-carnitine in the brain: revealed by Bioradiography. | Biochemical and biophysical research communications 20030711 |
| The active conformation of glutamate synthase and its binding to ferredoxin. | Journal of molecular biology 20030627 |
| Glutamine delays spontaneous apoptosis in neutrophils. | American journal of physiology. Cell physiology 20030601 |
| A molecular warhead and its target: tissue transglutaminase and Celiac Sprue. | Chemistry & biology 20030301 |
| Design, synthesis, and evaluation of gluten peptide analogs as selective inhibitors of human tissue transglutaminase. | Chemistry & biology 20030301 |
| A novel apoptosis-inducing protein from Helicobacter pylori. | Molecular microbiology 20030101 |
| Glutamine plays a role in superoxide production and the expression of p47phox, p22phox and gp91phox in rat neutrophils. | Clinical science (London, England : 1979) 20021001 |
| Localization and possible function of the glutamate transporter, EAAC1, in the rat retina. | Cell and tissue research 20021001 |
| The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-beta I and -delta. | The Journal of biological chemistry 20020913 |
| Flux through the hexosamine pathway is a determinant of nuclear factor kappaB- dependent promoter activation. | Diabetes 20020401 |
| Hexosamines regulate leptin production in 3T3-L1 adipocytes through transcriptional mechanisms. | Endocrinology 20020101 |
| Properties of glutaminase of crayfish CNS: implications for axon-glia signaling. | Neuroscience 20020101 |
| gamma-Glutamyltranspeptidase and gamma-glutamyl peptide ligases: fluorophosphonate and phosphonodifluoromethyl ketone analogs as probes of tetrahedral transition state and gamma-glutamyl-phosphate intermediate. | Methods in enzymology 20020101 |
| Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu? | Biochimica et biophysica acta 20011217 |
| Mechanism for acivicin inactivation of triad glutamine amidotransferases. | Biochemistry 20010130 |
| Glutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesis. | The Biochemical journal 20010115 |
| Stimulation by eicosapentaenoic acids of leptin mRNA expression and its secretion in mouse 3T3-L1 adipocytes in vitro. | Biochemical and biophysical research communications 20000413 |
| Glucose and streptozotocin stimulate p135 O-glycosylation in pancreatic islets. | Biochemical and biophysical research communications 20000107 |
| Antiviral effects of 6-diazo-5-oxo-L-norleucin on replication of herpes simplex virus type 1. | Antiviral research 19970201 |
| Role of glucosamine synthesis in the stimulation of TGF-alpha gene transcription by glucose and EGF. | The American journal of physiology 19960301 |
| Influence of twenty potentially antiviral substances on in vitro multiplication of hepatitis A virus. | Antiviral research 19860301 |
| Discriminative effect of gamma-glutamyl transpeptidase inhibitors on metabolism of leukotriene C4 in peritoneal cells. | Life sciences 19841119 |