24-Norchola-20,22-diene-3,14,17-triol, 21,23-epoxy-, (3β,5β,14β)-
Title | Journal |
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Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin. | Trials 20110101 |
Rostafuroxin: an ouabain-inhibitor counteracting specific forms of hypertension. | Biochimica et biophysica acta 20101201 |
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 1: experimental studies. | Science translational medicine 20101124 |
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies. | Science translational medicine 20101124 |
Targeting Ouabain- and Adducin-dependent mechanisms of hypertension and cardiovascular remodeling as a novel pharmacological approach. | Medical hypotheses 20070101 |
Ouabain-dependent signaling in caveolae as a novel therapeutic target for hypertension. | Cellular and molecular biology (Noisy-le-Grand, France) 20061230 |
Hypertension, Na+/Ca2+ exchanger, and Na+, K+-ATPase. | Kidney international 20060601 |
Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension. | American journal of physiology. Regulatory, integrative and comparative physiology 20060301 |
A new antihypertensive agent that antagonizes the prohypertensive effect of endogenous ouabain and adducin. | Cardiovascular & hematological agents in medicinal chemistry 20060101 |
Adducin and hypertension. | Pharmacogenomics 20051001 |
OASIS-HT: design of a pharmacogenomic dose-finding study. | Pharmacogenomics 20051001 |
PST 2238 as an antihypertensive compound that antagonizes the effect of endogenous cardiac glycosides. | Acta poloniae pharmaceutica 20050101 |
Ouabain antagonists as antihypertensive agents. | Current pharmaceutical design 20050101 |
Organ hypertrophic signaling within caveolae membrane subdomains triggered by ouabain and antagonized by PST 2238. | The Journal of biological chemistry 20040806 |
Antihypertensive compounds that modulate the Na-K pump. | Annals of the New York Academy of Sciences 20030401 |
Genes and hypertension. | Current pharmaceutical design 20030101 |
PST 2238: a new antihypertensive compound that modulates renal Na-K pump function without diuretic activity in Milan hypertensive rats. | Journal of cardiovascular pharmacology 20021201 |
Endogenous cardiotonic steroids. | Cellular and molecular biology (Noisy-le-Grand, France) 20010301 |