4-Hydroxyphenylpyruvic acid
Title | Journal |
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Discovery of Novel Inhibitors of the Tautomerase Activity of Macrophage Migration Inhibitory Factor (MIF). | Journal of biomolecular screening 20160601 |
Interaction of macrophage migration inhibitory factor with ceruloplasmin: role of labile copper ions. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20151001 |
Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440. | Journal of the American Chemical Society 20121010 |
Complete genome sequence of the melanogenic marine bacterium Marinomonas mediterranea type strain (MMB-1(T)). | Standards in genomic sciences 20120319 |
On the mode of action of the herbicides cinmethylin and 5-benzyloxymethyl-1, 2-isoxazolines: putative inhibitors of plant tyrosine aminotransferase. | Pest management science 20120301 |
Impaired DNA repair and genomic stability in hereditary tyrosinemia type 1. | Gene 20120301 |
Resolving phenylalanine metabolism sheds light on natural synthesis of penicillin G in Penicillium chrysogenum. | Eukaryotic cell 20120201 |
Multiple tyrosine metabolites are GPR35 agonists. | Scientific reports 20120101 |
Genome-wide association studies identified three independent polymorphisms associated with α-tocopherol content in maize kernels. | PloS one 20120101 |
Crystal structure of prephenate dehydrogenase from Streptococcus mutans. | International journal of biological macromolecules 20111101 |
Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy. | Plant physiology 20111101 |
Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase. | The Journal of biological chemistry 20111021 |
Evidence for the mechanism of hydroxylation by 4-hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase from intermediate partitioning in active site variants. | Biochemistry 20110906 |
4-hydroxyphenylpyruvate dioxygenase catalysis: identification of catalytic residues and production of a hydroxylated intermediate shared with a structurally unrelated enzyme. | The Journal of biological chemistry 20110722 |
A GC/MS-based metabolomic approach for diagnosing citrin deficiency. | Analytical and bioanalytical chemistry 20110601 |
Activation of ethylene-responsive p-hydroxyphenylpyruvate dioxygenase leads to increased tocopherol levels during ripening in mango. | Journal of experimental botany 20110601 |
Improved p-hydroxybenzoate production by engineered Pseudomonas putida S12 by using a mixed-substrate feeding strategy. | Applied microbiology and biotechnology 20110501 |
Metabonomic investigation of single and multiple strain Trypanosoma brucei brucei infections. | The American journal of tropical medicine and hygiene 20110105 |
Effects of ethyl pyruvate and other α-keto carboxylic acid derivatives in a rat model of multivisceral ischemia and reperfusion. | The Journal of surgical research 20110101 |
Targets downstream of Cdk8 in Dictyostelium development. | BMC developmental biology 20110101 |
GCOD - GeneChip Oncology Database. | BMC bioinformatics 20110101 |
Multi-omics approach to study the growth efficiency and amino acid metabolism in Lactococcus lactis at various specific growth rates. | Microbial cell factories 20110101 |
More than 200 genes required for methane formation from H₂ and CO₂ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. | Archaea (Vancouver, B.C.) 20110101 |
Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer. | PloS one 20110101 |
Metabolic engineering of the L-phenylalanine pathway in Escherichia coli for the production of S- or R-mandelic acid. | Microbial cell factories 20110101 |
Pyomelanin formation in Aspergillus fumigatus requires HmgX and the transcriptional activator HmgR but is dispensable for virulence. | PloS one 20110101 |
Correlation of gene expression and protein production rate - a system wide study. | BMC genomics 20110101 |
The c4h, tat, hppr and hppd genes prompted engineering of rosmarinic acid biosynthetic pathway in Salvia miltiorrhiza hairy root cultures. | PloS one 20110101 |
Structure and mechanism of the magnesium-independent aromatic prenyltransferase CloQ from the clorobiocin biosynthetic pathway. | Journal of molecular biology 20101210 |
Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations. | Protein & cell 20101101 |
Prephenate decarboxylases: a new prephenate-utilizing enzyme family that performs nonaromatizing decarboxylation en route to diverse secondary metabolites. | Biochemistry 20101026 |
Hereditary tyrosinemia type 1 metabolites impair DNA excision repair pathways. | Biochemical and biophysical research communications 20101008 |
The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes. | Acta crystallographica. Section F, Structural biology and crystallization communications 20101001 |
Tyrosine-derived 4-hydroxyphenylpyruvate reacts with ketone test fields of 3 commercially available urine dipsticks. | Veterinary clinical pathology 20100901 |
RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis. | Plant molecular biology 20100901 |
The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions. | PLoS genetics 20100901 |
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. | Proceedings of the National Academy of Sciences of the United States of America 20100622 |
Identification and characterization of the PhhR regulon in Pseudomonas putida. | Environmental microbiology 20100601 |
Comparative transcriptomics and proteomics of p-hydroxybenzoate producing Pseudomonas putida S12: novel responses and implications for strain improvement. | Applied microbiology and biotechnology 20100601 |
A new group of aromatic prenyltransferases in fungi, catalyzing a 2,7-dihydroxynaphthalene 3-dimethylallyl-transferase reaction. | The Journal of biological chemistry 20100528 |
Production of 4-hydroxyphenyllactic acid by Lactobacillus sp. SK007 fermentation. | Journal of bioscience and bioengineering 20100401 |
[Studies on the clinical manifestation and SLC25A13 gene mutation of Chinese patients with neonatal intrahepatic cholestasis caused by citrin deficiency]. | Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20100401 |
The rate-limiting catalytic steps of hydroxymandelate synthase from Amycolatopsis orientalis. | Biochemistry 20100309 |
Finding new enzymes from bacterial physiology: a successful approach illustrated by the detection of novel oxidases in Marinomonas mediterranea. | Marine drugs 20100101 |
The arthrobacter arilaitensis Re117 genome sequence reveals its genetic adaptation to the surface of cheese. | PloS one 20100101 |
Identification and Partial Characterization of an L-Tyrosine Aminotransferase (TAT) from Arabidopsis thaliana. | Biochemistry research international 20100101 |
Metabolic engineering of cofactor F420 production in Mycobacterium smegmatis. | PloS one 20100101 |
PhhR binds to target sequences at different distances with respect to RNA polymerase in order to activate transcription. | Journal of molecular biology 20091204 |
Characterization of keto-enol tautomerism of p-hydroxyphenylpyruvic acid using CE with amperometric detection and spectrometric analysis. | Journal of separation science 20091201 |
Role of Bacillus subtilis BacB in the synthesis of bacilysin. | The Journal of biological chemistry 20091113 |
Aspergillusol A, an alpha-glucosidase inhibitor from the marine-derived fungus Aspergillus aculeatus. | Journal of natural products 20091101 |
Characterization and expression profiling of 4-hydroxyphenylpyruvate dioxygenase gene (Smhppd) from Salvia miltiorrhiza hairy root cultures. | Molecular biology reports 20090901 |
Methyl jasmonate dramatically enhances the accumulation of phenolic acids in Salvia miltiorrhiza hairy root cultures. | Physiologia plantarum 20090901 |
NovQ is a prenyltransferase capable of catalyzing the addition of a dimethylallyl group to both phenylpropanoids and flavonoids. | The Journal of antibiotics 20090701 |
Characterization of a deep-sea sediment metagenomic clone that produces water-soluble melanin in Escherichia coli. | Marine biotechnology (New York, N.Y.) 20090101 |
Influence of growth regulators and sucrose concentrations on growth and rosmarinic acid production in calli and suspension cultures of Coleus blumei. | Natural product research 20090101 |
Prenyl transfer to aromatic substrates in the biosynthesis of aminocoumarins, meroterpenoids and phenazines: the ABBA prenyltransferase family. | Phytochemistry 20090101 |
Clinical, biochemical, and genetic analysis of a Korean neonate with hereditary tyrosinemia type 1. | Clinical chemistry and laboratory medicine 20090101 |
A comparative genomics approach to understanding the biosynthesis of the sunscreen scytonemin in cyanobacteria. | BMC genomics 20090101 |
13C-metabolic flux ratio and novel carbon path analyses confirmed that Trichoderma reesei uses primarily the respirative pathway also on the preferred carbon source glucose. | BMC systems biology 20090101 |
A novel mutation causing mild, atypical fumarylacetoacetase deficiency (Tyrosinemia type I): a case report. | Orphanet journal of rare diseases 20090101 |
Investigating the initial steps in the biosynthesis of cyanobacterial sunscreen scytonemin. | Journal of the American Chemical Society 20081119 |
Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides. | Fungal genetics and biology : FG & B 20081101 |
Isolation of herbicide-resistant 4-hydroxyphenylpyruvate dioxygenase from cultured Coptis japonica cells. | Bioscience, biotechnology, and biochemistry 20081101 |
Molecular cloning and characterization of Plasmodium falciparum transketolase. | Molecular and biochemical parasitology 20080701 |
Identification of a novel 4-hydroxyphenylpyruvate dioxygenase from the soil metagenome. | Biochemical and biophysical research communications 20080530 |
Experience of nitisinone for the pharmacological treatment of hereditary tyrosinaemia type 1. | Expert opinion on pharmacotherapy 20080501 |
Detection of Plasmodium falciparum derived macrophage migration inhibitory factor homologue in the sera of malaria patients. | Acta tropica 20080401 |
Two roads diverged: the structure of hydroxymandelate synthase from Amycolatopsis orientalis in complex with 4-hydroxymandelate. | Biochemistry 20080219 |
Alkaptonuria diagnosed in a 4-month-old baby girl: a case report. | Cases journal 20080101 |
The influence of ortho- and para-diphenoloxidase substrates on pigment formation in black yeast-like fungi. | Studies in mycology 20080101 |
Study on the kinetics of keto-enol tautomerism of p-hydroxyphenylpyruvic acid using capillary electrophoresis. | Journal of chromatography. A 20071221 |
Exploration of intraclonal adaptation mechanisms of Pseudomonas brassicacearum facing cadmium toxicity. | Environmental microbiology 20071101 |
Manifestation of hawkinsinuria in a patient compound heterozygous for hawkinsinuria and tyrosinemia III. | Molecular genetics and metabolism 20070801 |
The tyrosine degradation gene hppD is transcriptionally activated by HpdA and repressed by HpdR in Streptomyces coelicolor, while hpdA is negatively autoregulated and repressed by HpdR. | Molecular microbiology 20070801 |
Functional analysis of norcoclaurine synthase in Coptis japonica. | The Journal of biological chemistry 20070302 |
Housekeeping and tissue-specific genes in mouse tissues. | BMC genomics 20070101 |
Metabolic transcription analysis of engineered Escherichia coli strains that overproduce L-phenylalanine. | Microbial cell factories 20070101 |
Spectroscopic and electronic structure studies of the role of active site interactions in the decarboxylation reaction of alpha-keto acid-dependent dioxygenases. | Journal of inorganic biochemistry 20061201 |
Purification and characterization of a functionally active Mycobacterium tuberculosis prephenate dehydrogenase. | Protein expression and purification 20061001 |
Fungal metabolic model for tyrosinemia type 3: molecular characterization of a gene encoding a 4-hydroxy-phenyl pyruvate dioxygenase from Aspergillus nidulans. | Eukaryotic cell 20060801 |
Catalytic, noncatalytic, and inhibitory phenomena: kinetic analysis of (4-hydroxyphenyl)pyruvate dioxygenase from Arabidopsis thaliana. | Biochemistry 20060516 |
Crystal structure of prephenate dehydrogenase from Aquifex aeolicus. Insights into the catalytic mechanism. | The Journal of biological chemistry 20060505 |
The malate dehydrogenase isoforms from Trypanosoma brucei: subcellular localization and differential expression in bloodstream and procyclic forms. | International journal for parasitology 20060301 |
Macrophage migration inhibitory factor: isolation from bovine brain. | Biochemistry. Biokhimiia 20060101 |
A gold standard set of mechanistically diverse enzyme superfamilies. | Genome biology 20060101 |
Identification of potential CepR regulated genes using a cep box motif-based search of the Burkholderia cenocepacia genome. | BMC microbiology 20060101 |
DNA damage and repair in mammalian cells exposed to p-hydroxyphenylpyruvic acid. | Biochemical and biophysical research communications 20051216 |
Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl)pyruvate dioxygenase: active site contributions to drug inhibition. | Biochemical and biophysical research communications 20051209 |
Tocopherol content and activities of tyrosine aminotransferase and cystine lyase in Arabidopsis under stress conditions. | Journal of plant physiology 20050701 |
Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products. | Nature 20050616 |
Accumulation of multiple intermediates in the catalytic cycle of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis. | Biochemistry 20050517 |
p-Hydroxyphenylpyruvate dioxygenase inhibitor-resistant plants. | Pest management science 20050301 |
4-Hydroxyphenylpyruvate dioxygenase. | Archives of biochemistry and biophysics 20050101 |
The TyrA family of aromatic-pathway dehydrogenases in phylogenetic context. | BMC biology 20050101 |
Plantar keratoderma: a manifestation of tyrosinemia type II (Richner-Hanhart syndrome). | Annals of Saudi medicine 20050101 |
4-Hydroxyphenylpyruvate dioxygenase: a hybrid density functional study of the catalytic reaction mechanism. | Biochemistry 20040928 |
D-serine-induced nephrotoxicity: possible interaction with tyrosine metabolism. | Toxicology 20040901 |
Macrophage migration inhibitory factor: identification of the 30-kDa MIF-related protein in bovine brain. | Neurochemical research 20040701 |
The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase. | Plant physiology 20040401 |
Purification, cloning and functional expression of hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis in cell cultures of Coleus blumei. | Plant molecular biology 20040201 |
Engineering p-hydroxyphenylpyruvate dioxygenase to a p-hydroxymandelate synthase and evidence for the proposed benzene oxide intermediate in homogentisate formation. | Biochemistry 20040127 |
Engineering plant shikimate pathway for production of tocotrienol and improving herbicide resistance. | Plant physiology 20040101 |
Identification of the 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase required for coenzyme F(420) biosynthesis. | Archives of microbiology 20031201 |
Chemical oxidation of p-hydroxyphenylpyruvic acid in aqueous solution by capillary electrophoresis with an electrochemiluminescence detection system. | Analytical chemistry 20031201 |
4-Hydroxyphenylpyruvate dioxygenase as a drug discovery target. | Drug news & perspectives 20031001 |
Interaction of (4-hydroxyphenyl)pyruvate dioxygenase with the specific inhibitor 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione. | Biochemistry 20030902 |
Aspartate aminotransferase generates proagonists of the aryl hydrocarbon receptor. | Molecular pharmacology 20030901 |
Electrochemical study on the keto-enol tautomerization of p-hydroxyphenylpyruvic acid in aqueous solution. | Bioelectrochemistry (Amsterdam, Netherlands) 20030801 |
Novobiocin biosynthesis: inactivation of the putative regulatory gene novE and heterologous expression of genes involved in aminocoumarin ring formation. | Archives of microbiology 20030701 |
Isolation of a glucosyltransferase from Arabidopsis thaliana active in the metabolism of the persistent pollutant 3,4-dichloroaniline. | The Plant journal : for cell and molecular biology 20030501 |
Synthesis and antioxidant properties of a new lipophilic ascorbic acid analogue. | Bioorganic & medicinal chemistry 20030320 |
(4-Hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition. | Biochemistry 20030225 |
Mapping of chorismate mutase and prephenate dehydrogenase domains in the Escherichia coli T-protein. | European journal of biochemistry 20030201 |
Jasmonate is involved in the induction of tyrosine aminotransferase and tocopherol biosynthesis in Arabidopsis thaliana. | Planta 20021101 |
The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents. | The Journal of biological chemistry 20020712 |
Design, synthesis, and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hydroxyphenylpyruvate dioxygenase. | Bioorganic & medicinal chemistry letters 20020708 |
Mode of action of 4-hydroxyphenylpyruvate dioxygenase inhibition by triketone-type inhibitors. | Journal of medicinal chemistry 20020523 |
Ubiquitous production of macrophage migration inhibitory factor by human gastric and intestinal epithelium. | Gastroenterology 20020301 |
Aromatic amino acid biosynthesis and production of related compounds from p-hydroxyphenylpyruvic acid by rumen bacteria, protozoa and their mixture. | Amino acids 20020101 |
The Lly protein is essential for p-hydroxyphenylpyruvate dioxygenase activity in Legionella pneumophila. | FEMS microbiology letters 20010911 |
Macrophage migration inhibitory factor of the parasitic nematode Trichinella spiralis. | The Biochemical journal 20010715 |
[Fluorescence quenching method for the determination of p-hydroxyphenylpyruvic acid]. | Guang pu xue yu guang pu fen xi = Guang pu 20010601 |
Tyrosine and phenylalanine catabolism by Lactobacillus cheese flavor adjuncts. | Journal of dairy science 20010501 |
Impaired arachidonic (20:4n-6) and docosahexaenoic (22:6n-3) acid synthesis by phenylalanine metabolites as etiological factors in the neuropathology of phenylketonuria. | Molecular genetics and metabolism 20010301 |
The emerging periplasm-localized subclass of AroQ chorismate mutases, exemplified by those from Salmonella typhimurium and Pseudomonas aeruginosa. | Genome biology 20010101 |
Biosynthesis of nucleotides, flavins, and deazaflavins in Methanobacterium thermoautotrophicum. | The Journal of biological chemistry 19910525 |