1-[3-(trifluoromethyl)phenyl]piperazine
| Title | Journal |
|---|---|
| Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis. | Archives of toxicology 20161201 |
| Structure-dependent inhibition of the human α1β2γ2 GABAA receptor by piperazine derivatives: A novel mode of action. | Neurotoxicology 20151201 |
| Estrogenic effects and their action mechanism of the major active components of party pill drugs. | Toxicology letters 20121115 |
| Piperazine compounds as drugs of abuse. | Drug and alcohol dependence 20120501 |
| 1-(4,5,6,7-Tetra-hydro-thieno[3,2-c]pyridin-5-yl)-2-{4-[3-(trifluoro-meth-yl)phen-yl]piperazin-1-yl}ethanone. | Acta crystallographica. Section E, Structure reports online 20120501 |
| Determination of piperazine-type stimulants in human urine by means of microextraction in packed sorbent and high performance liquid chromatography-diode array detection. | Journal of pharmaceutical and biomedical analysis 20120305 |
| Rapid determination of piperazine-type stimulants in human urine by microextraction in packed sorbent after method optimization using a multivariate approach. | Journal of chromatography. A 20120127 |
| Microcrystalline identification of selected designer drugs. | Forensic science international 20120110 |
| Simultaneous determination of N-benzylpiperazine and 1-(3-trifluoromethylphenyl)piperazine in rat plasma by HPLC-fluorescence detection and its application to monitoring of these drugs. | Biomedical chromatography : BMC 20120101 |
| Acute oral toxicity evaluations of some zinc(II) complexes derived from 1-(2-salicylaldiminoethyl)piperazine Schiff bases in rats. | International journal of molecular sciences 20120101 |
| Structural insights from binding poses of CCR2 and CCR5 with clinically important antagonists: a combined in silico study. | PloS one 20120101 |
| Subjective effects in humans following administration of party pill drugs BZP and TFMPP alone and in combination. | Drug testing and analysis 20110901 |
| An analysis of legal highs: do they contain what it says on the tin? | Drug testing and analysis 20110901 |
| Determining the subjective and physiological effects of BZP combined with TFMPP in human males. | Psychopharmacology 20110401 |
| HPLC determination of methylphenidate and its metabolite, ritalinic acid, by high-performance liquid chromatography with peroxyoxalate chemiluminescence detection. | Analytical and bioanalytical chemistry 20110401 |
| Mephedrone (4-methylmethcathinone)-related deaths. | Journal of analytical toxicology 20110401 |
| The clinical toxicology of the designer 'party pills' benzylpiperazine and trifluoromethylphenylpiperazine. | Clinical toxicology (Philadelphia, Pa.) 20110301 |
| Effects of trifluoromethylphenylpiperazine (TFMPP) on interhemispheric communication. | Psychopharmacology 20110201 |
| Development of a rapid LC-MS/MS method for direct urinalysis of designer drugs. | Drug testing and analysis 20110101 |
| Current awareness of piperazines: pharmacology and toxicology. | Drug testing and analysis 20110101 |
| Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine. | Journal of analytical toxicology 20101101 |
| Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples. | Journal of analytical toxicology 20101001 |
| Randomised double-blind, placebo-controlled trial of the effects of the 'party pills' BZP/TFMPP alone and in combination with alcohol. | Journal of psychopharmacology (Oxford, England) 20100901 |
| Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans. | Journal of forensic sciences 20100901 |
| Determining the subjective effects of TFMPP in human males. | Psychopharmacology 20100801 |
| 3-Chloro-6-{4-[3-(trifluoro-meth-yl)phen-yl]piperazin-1-yl}pyridazine. | Acta crystallographica. Section E, Structure reports online 20100301 |
| Piperazines: a new class of drug of abuse has landed in Hong Kong. | Hong Kong medical journal = Xianggang yi xue za zhi 20100201 |
| Differences in harm from legal BZP/TFMPP party pills between North Island and South Island users in New Zealand: a case of effective industry self-regulation? | The International journal on drug policy 20100101 |
| Legal highs toxicity--symptomatology and clinical diagnosis in case series. | Przeglad lekarski 20100101 |
| 'Party pill' drugs--BZP and TFMPP. | The New Zealand medical journal 20091211 |
| In vivo interactions between BZP and TFMPP (party pill drugs). | The New Zealand medical journal 20090925 |
| Differentiation of the regioisomeric 2-, 3-, and 4-trifluoromethylphenylpiperazines (TFMPP) by GC-IRD and GC-MS. | Forensic science international 20090701 |
| Metabolic interactions with piperazine-based 'party pill' drugs. | The Journal of pharmacy and pharmacology 20090701 |
| Activation of serotonin 5-HT1-receptors decreased gripping-induced immobility episodes in taiep rats. | Neuroscience letters 20090109 |
| Dissociative and sympathomimetic toxicity associated with recreational use of 1-(3-trifluoromethylphenyl) piperazine (TFMPP) and 1-benzylpiperzine (BZP). | Journal of medical toxicology : official journal of the American College of Medical Toxicology 20081201 |
| Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand. | Drug and alcohol review 20081101 |
| Serotonin transduction cascades mediate variable changes in pyloric network cycle frequency in response to the same modulatory challenge. | Journal of neurophysiology 20080601 |
| Food restriction alters N'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine dihydrochloride (pramipexole)-induced yawning, hypothermia, and locomotor activity in rats: evidence for sensitization of dopamine D2 receptor-mediated effects. | The Journal of pharmacology and experimental therapeutics 20080501 |
| Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPP. | Journal of analytical toxicology 20080301 |
| [1-benzylpiperazine (BZP) and 1-(3-trifluorométhylphényl)pipérazine (TFMPP): emergence of two agents which lead to misuse]. | Annales pharmaceutiques francaises 20080301 |
| Detection of 1-benzylpiperazine and 1-(3-trifluoromethylphenyl)-piperazine in urine analysis specimens using GC-MS and LC-ESI-MS. | Journal of analytical toxicology 20080101 |
| The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines. | Bioorganic & medicinal chemistry 20071115 |
| Benzylpiperazine: a drug of abuse? | Journal of psychopharmacology (Oxford, England) 20071101 |
| MDMA-like behavioral effects of N-substituted piperazines in the mouse. | Pharmacology, biochemistry, and behavior 20071101 |
| Interaction of amphetamines and related compounds at the vesicular monoamine transporter. | The Journal of pharmacology and experimental therapeutics 20061001 |
| Effects of (Z)-3-hexenol, a major component of green odor, on anxiety-related behavior of the mouse in an elevated plus-maze test and biogenic amines and their metabolites in the brain. | Behavioural brain research 20060130 |
| Dopamine agonist-induced yawning in rats: a dopamine D3 receptor-mediated behavior. | The Journal of pharmacology and experimental therapeutics 20050701 |
| Metabolism of designer drugs of abuse. | Current drug metabolism 20050601 |
| Development of simultaneous gas chromatography-mass spectrometric and liquid chromatography-electrospray ionization mass spectrometric determination method for the new designer drugs, N-benzylpiperazine (BZP), 1-(3-trifluoromethylphenyl)piperazine (TFMPP) and their main metabolites in urine. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525 |
| Differential effects of 5-HT2C receptor ligands on place conditioning and locomotor activity in rats. | European journal of pharmacology 20050516 |
| N-substituted piperazines abused by humans mimic the molecular mechanism of 3,4-methylenedioxymethamphetamine (MDMA, or 'Ecstasy'). | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050301 |
| Simultaneous separation of different types of amphetamine and piperazine designer drugs by capillary electrophoresis with a chiral selector. | Journal of forensic sciences 20050301 |
| Reinforcing and discriminative stimulus effects of 1-benzylpiperazine and trifluoromethylphenylpiperazine in rhesus monkeys. | Drug and alcohol dependence 20050214 |
| Isolation, identification and excretion profile of the principal urinary metabolite of the recently banned designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP) in rats. | Xenobiotica; the fate of foreign compounds in biological systems 20050101 |
| Discriminative stimulus effects of ethanol in rats using a three-choice ethanol-midazolam-water discrimination. | Behavioural pharmacology 20041201 |
| Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. | Naunyn-Schmiedeberg's archives of pharmacology 20040801 |
| Antiallodynic effects of intrathecally administered 5-HT(2C) receptor agonists in rats with nerve injury. | Pain 20040301 |
| Anxiogenic effects in the rat elevated plus-maze of 5-HT(2C) agonists into ventral but not dorsal hippocampus. | Behavioural pharmacology 20040201 |
| Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor. | European journal of pharmacology 20040126 |
| Cytochrome P450 dependent metabolism of the new designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP). In vivo studies in Wistar and Dark Agouti rats as well as in vitro studies in human liver microsomes. | Biochemical pharmacology 20040115 |
| Common drugs of abuse--Part II. | The Journal of practical nursing 20040101 |
| New designer drug 1-(3-trifluoromethylphenyl) piperazine (TFMPP): gas chromatography/mass spectrometry and liquid chromatography/mass spectrometry studies on its phase I and II metabolism and on its toxicological detection in rat urine. | Journal of mass spectrometry : JMS 20030901 |
| Behavioural evidence of agonist-like effect of isoteoline at 5-HT1B serotonergic receptors in mice. | The Journal of pharmacy and pharmacology 20030101 |
| Involvement of 5-HT(2A/2B/2C) receptors on memory formation: simple agonism, antagonism, or inverse agonism? | Cellular and molecular neurobiology 20021201 |
| Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy. | Epilepsia 20021101 |
| Role of serotonin, gamma-aminobutyric acid, and glutamate in the behavioral thermoregulation of female tilapia during the prespawning phase. | The Journal of experimental zoology 20021001 |
| Metachlorophenylpiperazine (m-CPP) induced intracavernous pressure responses in anaesthetized rats. | International journal of impotence research 20020801 |
| Participation of 5-HT(1B) receptors in the inhibitory actions of serotonin on masculine sexual behaviour of mice: pharmacological analysis in 5-HT(1B) receptor knockout mice. | British journal of pharmacology 20020801 |
| Full substitution of the discriminative cue of a 5-HT(1A/1B/2C) agonist with the combined administration of a 5-HT(1B/2C) and a 5-HT(1A) agonist. | Behavioural pharmacology 20020701 |
| The atypical 5-HT2 receptor mediating tachycardia in pithed rats: pharmacological correlation with the 5-HT2A receptor subtype. | British journal of pharmacology 20020301 |
| Effects of serotine receptors agonists, TFMPP and CGS12066B, on regional serotonin synthesis in the rat brain: an autoradiographic study. | Journal of neurochemistry 20020301 |
| Structure-affinity relationships of a unique nicotinic ligand: N(1)-dimethyl-N(4)-phenylpiperazinium iodide (DMPP). | Journal of medicinal chemistry 20011108 |
| Piperazine-like compounds: a new group of designer drugs-of-abuse on the European market. | Forensic science international 20010915 |
| RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity. | British journal of pharmacology 20010901 |
| Discriminative stimulus properties of indorenate, a 5-HT1A, 5-HT1B and 5-HT2C agonist: a study in rats. | Journal of psychopharmacology (Oxford, England) 20010301 |
| Serotonergic modulation of retinal input to the mouse suprachiasmatic nucleus mediated by 5-HT1B and 5-HT7 receptors. | Journal of biological rhythms 20010201 |
| Modulation of 5-HT(2A) receptor-mediated head-twitch behaviour in the rat by 5-HT(2C) receptor agonists. | Pharmacology, biochemistry, and behavior 20010101 |
| The role of serotonin(2) receptors in mediating cocaine-induced convulsions. | Pharmacology, biochemistry, and behavior 20000401 |
| Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors. | Synapse (New York, N.Y.) 20000201 |
| The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. | European journal of pharmacology 19970501 |
| Two amino acid differences in the sixth transmembrane domain are partially responsible for the pharmacological differences between the 5-HT1D beta and 5-HT1E 5-hydroxytryptamine receptors. | Journal of neurochemistry 19961101 |
| Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. | Journal of neurochemistry 19960101 |
| Penile erection and yawning induced by 5-HT1C receptor agonists in male rats: relationship with dopaminergic and oxytocinergic transmission. | European journal of pharmacology 19940811 |
| Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. | The Journal of biological chemistry 19930825 |
| Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. | Molecular pharmacology 19930801 |
| Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. | Molecular pharmacology 19930301 |
| Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. | Molecular pharmacology 19930301 |
| Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor. | Molecular pharmacology 19930301 |
| Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase. | Proceedings of the National Academy of Sciences of the United States of America 19930115 |
| Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta. | Proceedings of the National Academy of Sciences of the United States of America 19920415 |
| Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor. | Molecular pharmacology 19910801 |
| In-vivo metabolism in the rat and mouse of antrafenine to 1-m-trifluoromethylphenylpiperazine. | The Journal of pharmacy and pharmacology 19850101 |