Changes in lysyl oxidase (LOX) distribution and its decreased activity in keratoconus corneas.

Experimental eye research 20121101

The role of lysyl oxidase family members in the stabilization of abdominal aortic aneurysms.

American journal of physiology. Heart and circulatory physiology 20121015

LOXL1 deficiency in the lamina cribrosa as candidate susceptibility factor for a pseudoexfoliation-specific risk of glaucoma.

Ophthalmology 20120901

Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.

Breast cancer research and treatment 20120801

Factor XIIIA transglutaminase expression and secretion by osteoblasts is regulated by extracellular matrix collagen and the MAP kinase signaling pathway.

Journal of cellular physiology 20120701

Fibroblasts--a key host cell type in tumor initiation, progression, and metastasis.

Upsala journal of medical sciences 20120501

Effect of defective collagen synthesis on epithelial implant interface: lathyritic model in dogs. An experimental preliminary study.

The Journal of oral implantology 20120401

The enzymatic activity of lysyl oxidas-like-2 (LOXL2) is not required for LOXL2-induced inhibition of keratinocyte differentiation.

The Journal of biological chemistry 20120127

Copper deficiency induced emphysema is associated with focal adhesion kinase inactivation.

PloS one 20120101

Variations in LOXL1 associated with exfoliation glaucoma do not affect amine oxidase activity.

Molecular vision 20120101

Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts.

PloS one 20120101

Triarylmethanes, a new class of cx50 inhibitors.

Frontiers in pharmacology 20120101

Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral.

Bone 20111201

Lysyl oxidase regulates MMTV promoter: indirect evidence of histone H1 involvement.

Biochemistry and cell biology = Biochimie et biologie cellulaire 20111201

Methods to reduce the contraction of tissue-engineered buccal mucosa for use in substitution urethroplasty.

European urology 20111001

Effects of prolonged vaginal distension and β-aminopropionitrile on urinary continence and urethral structure.

Urology 20111001

Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans.

The Journal of clinical investigation 20110502

[Effect of lysyl oxidase on migration and adhesion of human gastric cancer HGC-27 cells in vitro].

Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110501

A new unifying hypothesis for lathyrism, konzo and tropical ataxic neuropathy: nitriles are the causative agents.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110301

Life-long programming implications of exposure to tobacco smoking and nicotine before and soon after birth: evidence for altered lung development.

International journal of environmental research and public health 20110301

The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin.

Molecular biology reports 20110101

In vitro modulation of cartilage shape plasticity by biochemical regulation of matrix remodeling.

Tissue engineering. Part A 20110101

Chromatin supraorganization, mitotic abnormalities and proliferation in cells with increased or down-regulated lox expression: Indirect evidence of a LOX-histone H1 interaction in vivo.

Micron (Oxford, England : 1993) 20110101

Reciprocal roles of angiotensin II and Angiotensin II Receptors Blockade (ARB) in regulating Cbfa1/RANKL via cAMP signaling pathway: possible mechanism for hypertension-related osteoporosis and antagonistic effect of ARB on hypertension-related osteoporosis.

International journal of molecular sciences 20110101

The ratio 1660/1690 cm(-1) measured by infrared microspectroscopy is not specific of enzymatic collagen cross-links in bone tissue.

PloS one 20110101

Lysyl oxidase silencing impairs keratinocyte differentiation in a reconstructed-epidermis model.

Experimental dermatology 20101201

High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function.

Diabetes 20101201

Lung interstitial cells during alveolarization.

Korean journal of pediatrics 20101201

T3 affects expression of collagen I and collagen cross-linking in bone cell cultures.

Biochemical and biophysical research communications 20101112

In search of a new therapeutic target for the treatment of genetically triggered thoracic aortic aneurysms and cardiovascular conditions: insights from human and animal lathyrism.

Interactive cardiovascular and thoracic surgery 20100901

Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment.

Nature medicine 20100901

Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion.

Oncogene 20100708

Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor.

The Journal of biological chemistry 20100702

Intracellular lysyl oxidase: effect of a specific inhibitor on nuclear mass in proliferating cells.

Biochemical and biophysical research communications 20100611

Id1, inhibitor of differentiation, is a key protein mediating anti-tumor responses of gamma-tocotrienol in breast cancer cells.

Cancer letters 20100528

The effect of lathyrism on dentin structure of the rat incisors: a morphometric and scanning electron microscopic investigation.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20100501

Pharmacologically induced thoracic and abdominal aortic aneurysms in mice.

Hypertension (Dallas, Tex. : 1979) 20100501

Bleomycin induces upregulation of lysyl oxidase in cultured human fetal lung fibroblasts.

Acta pharmacologica Sinica 20100501

Lysyl oxidase expression and inhibition in uveal melanoma.

Melanoma research 20100401

Differential effects of homocysteine and beta aminopropionitrile on preosteoblastic MC3T3-E1 cells.

Bone 20100301

Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype.

British journal of cancer 20100202

Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer.

Journal of carcinogenesis 20100101

Experimental models of abdominal aortic aneurysms.

The open cardiovascular medicine journal 20100101

Bioreductively activated lysyl oxidase inhibitors against hypoxic tumours.

ChemMedChem 20091001

Comparison of the effects of semicarbazide and beta-aminopropionitrile on the arterial extracellular matrix in the Brown Norway rat.

Toxicology and applied pharmacology 20090915

Functional consequences of mitochondrial DNA deletions in human skin fibroblasts: increased contractile strength in collagen lattices is due to oxidative stress-induced lysyl oxidase activity.

The American journal of pathology 20090901

Reduced collagen biosynthesis is the hallmark of cerebral aneurysm: contribution of interleukin-1beta and nuclear factor-kappaB.

Arteriosclerosis, thrombosis, and vascular biology 20090701

Sea urchin arylsulfatase, an extracellular matrix component, is involved in gastrulation during embryogenesis.

Development genes and evolution 20090601

Proteoglycan production is required in initial stages of new cartilage matrix formation but inhibits integrative cartilage repair.

Journal of tissue engineering and regenerative medicine 20090201

Wound-healing modulation in upper airway stenosis-Myths and facts.

Head & neck 20090101

The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells.

PloS one 20090101

Osteitis fibrosa is mediated by Platelet-Derived Growth Factor-A via a phosphoinositide 3-kinase-dependent signaling pathway in a rat model for chronic hyperparathyroidism.

Endocrinology 20081101

Ultrastructural and histomorphometric alterations of rat jaw bones after experimental induction of lathyrism.

Archives of oral biology 20081001

Lysyl oxidase oxidizes cell membrane proteins and enhances the chemotactic response of vascular smooth muscle cells.

The Journal of biological chemistry 20080829

Collagen cross-linking influences osteoblastic differentiation.

Calcified tissue international 20080501

Contribution of collagen network features to functional properties of engineered cartilage.

Osteoarthritis and cartilage 20080301

Cartilage growth and remodeling: modulation of balance between proteoglycan and collagen network in vitro with beta-aminopropionitrile.

Osteoarthritis and cartilage 20080101

Effect of cellular aging on collagen biosynthesis: I. Methodological considerations and pharmacological applications.

Archives of gerontology and geriatrics 20080101

50 years ago in CORR : skeletal lesions produced by aminonitriles by Ignacio V. Ponseti MD CORR 1957;9:131-144.

Clinical orthopaedics and related research 20080101

Active lysyl oxidase (LOX) correlates with focal adhesion kinase (FAK)/paxillin activation and migration in invasive astrocytes.

Neuropathology and applied neurobiology 20071201

Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis.

American journal of physiology. Gastrointestinal and liver physiology 20071201

Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta.

Drug metabolism and disposition: the biological fate of chemicals 20071001

Essential role of lysyl oxidases in notochord development.

Developmental biology 20070715

Regulation of elastin promoter by lysyl oxidase and growth factors: cross control of lysyl oxidase on TGF-beta1 effects.

Matrix biology : journal of the International Society for Matrix Biology 20070701

Distinct steps of cross-linking, self-association, and maturation of tropoelastin are necessary for elastic fiber formation.

Journal of molecular biology 20070608

Mechanism for covalent binding of rofecoxib to elastin of rat aorta.

The Journal of pharmacology and experimental therapeutics 20070301

The aminolysis of N-aroyl beta-lactams occurs by a concerted mechanism.

Organic & biomolecular chemistry 20070207

Bonding of articular cartilage using a combination of biochemical degradation and surface cross-linking.

Arthritis research & therapy 20070101

Unilateral pedicle screws asymmetric tethering: an innovative method to create idiopathic deformity.

Journal of orthopaedic surgery and research 20070101

Functional diversity of lysyl hydroxylase 2 in collagen synthesis of human dermal fibroblasts.

Experimental cell research 20061101

Use of an in vitro model of tissue-engineered skin to investigate the mechanism of skin graft contraction.

Tissue engineering 20061101

A novel type of lysine oxidase: L-lysine-epsilon-oxidase.

Biochimica et biophysica acta 20061001

Periodontal & systemic bone changes in rats with experimental lathyrism.

The Indian journal of medical research 20060401

Investigation of keratinocyte regulation of collagen I synthesis by dermal fibroblasts in a simple in vitro model.

The British journal of dermatology 20060301

The lysyl oxidase LOX is absent in basal and squamous cell carcinomas and its knockdown induces an invading phenotype in a skin equivalent model.

Clinical cancer research : an official journal of the American Association for Cancer Research 20060301

Examination of the stress-induced expression of the collagen binding heat shock protein, hsp47, in Xenopus laevis cultured cells and embryos.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20060101

Phenotypical and functional characterization of alveolar macrophage subpopulations in the lungs of NO2-exposed rats.

Respiratory research 20060101

Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism.

Cancer research 20051215

Collagen and elastin cross-linking: a mechanism of constrictive remodeling after arterial injury.

American journal of physiology. Heart and circulatory physiology 20051101

Members of the lysyl oxidase family are expressed during the development of the frog Xenopus laevis.

Differentiation; research in biological diversity 20051001

The Formation of lysine tyrosylquinone (LTQ) is a self-processing reaction. Expression and characterization of a Drosophila lysyl oxidase.

Biochemistry 20050906

Abnormal deposition of collagen around hepatocytes in Wilson's disease is associated with hepatocyte specific expression of lysyl oxidase and lysyl oxidase like protein-2.

Journal of hepatology 20050901

Kinetics of collagen crosslinking in adult bovine articular cartilage.

Osteoarthritis and cartilage 20050801

Drosophila lysyl oxidases Dmloxl-1 and Dmloxl-2 are differentially expressed and the active DmLOXL-1 influences gene expression and development.

The Journal of biological chemistry 20050617

Treatment of cartilage with beta-aminopropionitrile accelerates subsequent collagen maturation and modulates integrative repair.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20050501

Determination of systemically & locally induced periodontal defects in rats.

The Indian journal of medical research 20050301

Inhibition of breast adenocarcinoma growth by intratumoral injection of lipophilic long-acting lathyrogens.

Anti-cancer drugs 20050201

Inhibition of lysyl oxidase activity can delay phenotypic modulation of chondrocytes in two-dimensional culture.

Osteoarthritis and cartilage 20050201

The central role of vascular extracellular matrix and basement membrane remodeling in metabolic syndrome and type 2 diabetes: the matrix preloaded.

Cardiovascular diabetology 20050101

Synthesis and evaluation of long-acting D-penicillamine derivatives.

Connective tissue research 20050101

Effect of bestatin on angiotensin I-, II- and III-induced collagen gel contraction in cardiac fibroblasts.

Journal of the renin-angiotensin-aldosterone system : JRAAS 20041201

The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells.

The Journal of biological chemistry 20040924

A role for lysyl oxidase regulation in the control of normal collagen deposition in differentiating osteoblast cultures.

Journal of cellular physiology 20040701

Medical management of superficial digital flexor tendonitis: a comparative study in 219 horses (1992-2000).

Equine veterinary journal 20040701

The role of ascorbic acid on collagen structure and levels of serum interleukin-6 and tumour necrosis factor-alpha in experimental lathyrism.

Clinical and experimental dermatology 20040301

Collagen production in cardiac fibroblasts during inhibition of angiotensin-converting enzyme and aminopeptidases.

Journal of hypertension 20040101

Tropoelastin inhibits vascular calcification via 67-kDa elastin binding protein in cultured bovine aortic smooth muscle cells.

Journal of atherosclerosis and thrombosis 20040101

The effects of beta-aminopropionitrile on colonic anastomosis in rats.

Journal of investigative surgery : the official journal of the Academy of Surgical Research 20040101

Expression and purification of enzymatically active forms of the human lysyl oxidase-like protein 4.

The Journal of biological chemistry 20031226

Effect of dexamethasone on root resorption after delayed replantation of rat tooth.

Journal of endodontics 20031201

Purification of enzymatically active human lysyl oxidase and lysyl oxidase-like protein from Escherichia coli inclusion bodies.

Protein expression and purification 20031001

TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice.

Thorax 20030901

Collagen crosslinking and cell density have distinct effects on fibroblast-mediated contraction of collagen gels.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 20030801

Elastic fiber production in cardiovascular tissue-equivalents.

Matrix biology : journal of the International Society for Matrix Biology 20030601

Pathological observation of brain arteries and spontaneous aneurysms in hypertensive rats.

Chinese medical journal 20030301

Chemical and biomechanical characterization of hyperhomocysteinemic bone disease in an animal model.

BMC musculoskeletal disorders 20030101

Treatment of acute schistosomiasis mansoni with praziquantel and an antifibrotic agent in mice. Maintenance of resistance to infection.

Arzneimittel-Forschung 20030101

Collagen fibrillogenesis by chondrocytes in alginate.

Tissue engineering 20021201

Metabolism of tresperimus by rat aorta semicarbazide-sensitive amine oxidase (SSAO).

Fundamental & clinical pharmacology 20021201

An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats.

Journal of vascular surgery 20021001

Low density lipoproteins downregulate lysyl oxidase in vascular endothelial cells and the arterial wall.

Arteriosclerosis, thrombosis, and vascular biology 20020901

Biochemical and toxicological evaluation of agent-cofactor reactivity as a mechanism of action for osteolathyrism.

Toxicology 20020815

A molecular role for lysyl oxidase in breast cancer invasion.

Cancer research 20020801

Regulation of the expression of lysyl oxidase mRNA in cultured rabbit retinal pigment epithelium cells.

Matrix biology : journal of the International Society for Matrix Biology 20020601

Osteolathyrism in the rat: an X-ray diffraction study of collagen from normal and lathyritic rats. 1964.

Academic radiology 20020501

Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

The Journal of biological chemistry 20020419

Integrative articular cartilage repair: dependence on developmental stage and collagen metabolism.

Osteoarthritis and cartilage 20020301

Effect of beta-aminopropionitrile and hyaluronic acid on repair of collagenase-induced injury of the rabbit Achilles tendon.

Journal of comparative pathology 20020101

Effects of hydrocortisone and beta-aminopropionitrile on stress-strain and stress-relaxation behaviors, and birefringent retardation of collagen fibers in the rat incisor periodontal ligament.

Connective tissue research 20020101

[Granular media calcinosis of the aorta. Structural findings, historical review and pathogenetic significance].

Zeitschrift fur Kardiologie 20011201

Beta-aminopropionitrile treatment can accelerate recovery of mice after spinal cord injury.

European journal of pharmacology 20011026

Effects of beta-aminopropionitrile on equine tendon metabolism in vitro and on effects of insulin-like growth factor-I on matrix production by equine tenocytes.

American journal of veterinary research 20011001

Force deficits after stretches of activated rat muscle-tendon complex with reduced collagen cross-linking.

European journal of applied physiology 20010901

Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage.

The Journal of biological chemistry 20010629

Building Elastin. Incorporation of recombinant human tropoelastin into extracellular matrices using nonelastogenic rat-1 fibroblasts as a source for lysyl oxidase.

American journal of respiratory cell and molecular biology 20010601

Amine oxidase-like activity of polyphenols. Mechanism and properties.

European journal of biochemistry 20010401

Characterization of a model compound for the lysine tyrosylquinone cofactor of lysyl oxidase.

Biochemical and biophysical research communications 20010216

Experimental copper deficiency, chromium deficiency and additional molybdenum supplementation in goats--pathological findings.

Acta veterinaria Scandinavica 20010101

Teratological studies on craniofacial malformations.

Swedish dental journal. Supplement 19970101

The effect of beta-aminopropionitrile on elastin gene expression in smooth muscle cell cultures.

Biochemical and biophysical research communications 19910916