Home Other Building Blocks Cloperastine hydrochloride

Cloperastine hydrochloride

CAS No.:
14984-68-0
Catalog Number:
AG001M23
Molecular Formula:
C20H25Cl2NO
Molecular Weight:
366.3246
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$38
- +
5g
95%
In Stock USA
United States
$114
- +
25g
95%
In Stock USA
United States
$400
- +
Product Description
Catalog Number:
AG001M23
Chemical Name:
Cloperastine hydrochloride
CAS Number:
14984-68-0
Molecular Formula:
C20H25Cl2NO
Molecular Weight:
366.3246
MDL Number:
MFCD00079012
IUPAC Name:
1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine;hydrochloride
InChI:
InChI=1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H
InChI Key:
UNPLRYRWJLTVAE-UHFFFAOYSA-N
SMILES:
Clc1ccc(cc1)C(c1ccccc1)OCCN1CCCCC1.Cl
EC Number:
239-067-8
NSC Number:
758635
Properties
Complexity:
318  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
365.131g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
366.326g/mol
Monoisotopic Mass:
365.131g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
12.5A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Cloperastine rescues impairment of passive avoidance response in mice prenatally exposed to diethylstilbestrol. Environmental toxicology 20140201
Development of chromatographic methods for the determination of genotoxic impurities in cloperastine fendizoate. Journal of pharmaceutical and biomedical analysis 20120305
Cloperastine-based cough syrup and acute dystonic reactions. Developmental medicine and child neurology 20120301
[Is the GIRK channel a possible target in the development of a novel therapeutic drug of urinary disturbance?]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110401
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay. Antimicrobial agents and chemotherapy 20100901
[Novel antidepressant-like action of drugs possessing GIRK channel blocking action in rats]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100501
Simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma by liquid chromatography-tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20100205
Ameliorating effects of cloperastine on dysfunction of the urinary bladder caused by cerebral infarction in conscious rats. Canadian journal of physiology and pharmacology 20091101
Effects of solid-state reaction between paracetamol and cloperastine hydrochloride on the pharmaceutical properties of their preparations. International journal of pharmaceutics 20070420
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents. Drugs under experimental and clinical research 20040101
Properties