(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1h-imidazole hydrochloride
| Title | Journal |
|---|---|
| A comparison of severe hemodynamic disturbances between dexmedetomidine and propofol for sedation in neurocritical care patients. | Critical care medicine 20140701 |
| Vasovagal syncope and severe bradycardia following intranasal dexmedetomidine for pediatric procedural sedation. | Paediatric anaesthesia 20140401 |
| Neurotoxic effects of dexmedetomidine in fetal cynomolgus monkey brains. | The Journal of toxicological sciences 20140401 |
| Dexmedetomidine premedication attenuates concanavalin A-induced hepatitis in mice. | The Journal of toxicological sciences 20140101 |
| Premedication with intravenous dexmedetomidine-midazolam suppresses fentanyl-induced cough. | Irish journal of medical science 20121201 |
| Pharmacokinetics and pharmacodynamics of intravenous dexmedetomidine in healthy Korean subjects. | Journal of clinical pharmacy and therapeutics 20121201 |
| Evaluation of a ketamine-propofol drug combination with or without dexmedetomidine for intravenous anesthesia in cats undergoing ovariectomy. | Journal of the American Veterinary Medical Association 20121115 |
| Dexmedetomidine in the emergency department: assessing safety and effectiveness in difficult-to-sedate acute behavioural disturbance. | Emergency medicine journal : EMJ 20121101 |
| Protective effect of dexmedetomidine in a rat model of α-naphthylthiourea-induced acute lung injury. | The Journal of surgical research 20121101 |
| Opioid-free perioperative analgesia for hemicolectomy in a patient with opioid-induced delirium: a case report and review of the analgesic efficacy of the alpha-2 agonist agents. | Pain practice : the official journal of World Institute of Pain 20121101 |
| The effects of dexmedetomidine on mesenteric arterial occlusion-associated gut ischemia and reperfusion-induced gut and kidney injury in rabbits. | The Journal of surgical research 20121101 |
| Intramuscular dexmedetomidine: an effective route of sedation preserves background activity for pediatric electroencephalograms. | The Journal of pediatrics 20121101 |
| Dexmedetomidine for sedation in the parturient with respiratory failure requiring noninvasive ventilation. | Respiratory care 20121101 |
| Attenuation of spinal cord ischemia-reperfusion injury by specific α-2a receptor activation with dexmedetomidine. | Journal of vascular surgery 20121101 |
| A randomised comparison of two intranasal dexmedetomidine doses for premedication in children. | Anaesthesia 20121101 |
| Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl. | American journal of critical care : an official publication, American Association of Critical-Care Nurses 20121101 |
| Dexmedetomidine decreases hyperalgesia in neuropathic pain by increasing acetylcholine in the spinal cord. | Neuroscience letters 20121031 |
| Hemodynamic effects of dexmedetomidine in critically ill neonates and infants with heart disease. | Pediatric cardiology 20121001 |
| Effects of sedation on echocardiographic variables of left atrial and left ventricular function in healthy cats. | Journal of feline medicine and surgery 20121001 |
| Posterior tibial nerve sensory blockade duration prolonged by adding dexmedetomidine to ropivacaine. | Anesthesia and analgesia 20121001 |
| Maternal and preterm fetal sheep responses to dexmedetomidine. | International journal of obstetric anesthesia 20121001 |
| Use of dexmedetomidine to prevent pulmonary injury after pneumoperitoneum in ventilated rats. | Surgical laparoscopy, endoscopy & percutaneous techniques 20121001 |
| Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia. | Paediatric anaesthesia 20120901 |
| Effects of dexmedetomidine on conditioned pain modulation in humans. | European journal of pain (London, England) 20120901 |
| Effects of propofol and dexmedetomidine on motor coordination and analgesia: a comparative analysis. | International journal of clinical pharmacology and therapeutics 20120901 |
| Dexmedetomidine for transport of a spontaneously breathing combative child. | Pediatrics 20120901 |
| Hemodynamic effects in dogs after intramuscular administration of a combination of dexmedetomidine-butorphanol-tiletamine-zolazepam or dexmedetomidine-butorphanol-ketamine. | American journal of veterinary research 20120901 |
| Preventive effect of dexmedetomidine in ischemia-reperfusion injury. | The Journal of craniofacial surgery 20120901 |
| Treatment of delirium following cardiac surgery. | Journal of cardiac surgery 20120901 |
| Pharmacologic prevention and treatment of delirium in critically ill and non-critically ill hospitalised patients: a review of data from prospective, randomised studies. | Best practice & research. Clinical anaesthesiology 20120901 |
| Plasma glucose, insulin, free fatty acids, lactate and cortisol concentrations in dexmedetomidine-sedated dogs with or without MK-467: a peripheral α-2 adrenoceptor antagonist. | Veterinary journal (London, England : 1997) 20120801 |
| The effect of dexmedetomidine on arterial-cardiac baroreflex function assessed by spectral and transfer function analysis. | Journal of anesthesia 20120801 |
| The application of dexmedetomidine in children undergoing vitreoretinal surgery. | Journal of anesthesia 20120801 |
| Heart rate variability dynamics during low-dose propofol and dexmedetomidine anesthesia. | Annals of biomedical engineering 20120801 |
| Use of dexmedetomidine for the treatment of alcohol withdrawal syndrome in critically ill patients: a retrospective case series. | Journal of anesthesia 20120801 |
| Superficial temporal artery-middle cerebral artery bypass using local anesthesia and a sedative without endotracheal general anesthesia. | Journal of neurosurgery 20120801 |
| Dexmedetomidine dose dependently decreases oral tissue blood flow during sevoflurane and propofol anesthesia in rabbits. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20120801 |
| Dexmedetomidine: a guide to its use for sedation in the US. | Clinical drug investigation 20120801 |
| [Successful anesthetic management in a patient with chronic obstructive pulmonary disease (COPD) using dexmedetomidine and combined spinal-epidural anesthesia for low anterior resection of the rectum]. | Masui. The Japanese journal of anesthesiology 20120801 |
| Dexmedetomidine and ketamine: an effective alternative for procedural sedation? | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20120701 |
| Neonatal administration with dexmedetomidine does not impair the rat hippocampal synaptic plasticity later in adulthood. | Paediatric anaesthesia 20120701 |
| The influence of a continuous rate infusion of dexmedetomidine on the nociceptive withdrawal reflex and temporal summation during isoflurane anaesthesia in dogs. | Veterinary anaesthesia and analgesia 20120701 |
| Dexmedetomidine prevents alterations of intestinal microcirculation that are induced by surgical stress and pain in a novel rat model. | Anesthesia and analgesia 20120701 |
| Isoflurane but not halothane minimum alveolar concentration-sparing response of dexmedetomidine is enhanced in rats chronically treated with selective α2-adrenoceptor agonist. | Laboratory animals 20120701 |
| Dexmedetomidine reduces emergence agitation after tonsillectomy in children by sevoflurane anesthesia: a case-control study. | International journal of pediatric otorhinolaryngology 20120701 |
| Direct protective effects of dexmedetomidine against myocardial ischemia-reperfusion injury in anesthetized pigs. | Shock (Augusta, Ga.) 20120701 |
| Effect of dexmedetomidine on brain edema and neurological outcomes in surgical brain injury in rats. | Anesthesia and analgesia 20120701 |
| Efficacy of dexmedetomidine in suppressing cardiovascular and hormonal responses to general anaesthesia for caesarean delivery: a dose-response study. | International journal of obstetric anesthesia 20120701 |
| Medications for sedation in patients with prolonged mechanical ventilation. | JAMA 20120627 |
| CYP2A6 genetic variation and dexmedetomidine disposition. | European journal of clinical pharmacology 20120601 |
| Is the addition of dexmedetomidine to a ketamine-propofol combination in pediatric cardiac catheterization sedation useful? | Pediatric cardiology 20120601 |
| Dexmedetomidine and hydroxyzine synergistically potentiate the hypnotic activity of propofol in mice. | Journal of anesthesia 20120601 |
| Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials. | Anesthesiology 20120601 |
| Dexmedetomidine infusion for sedation in the intensive care setting in an infant with airway compromise due to congenital mediastinal neuroblastoma. | Paediatric anaesthesia 20120601 |
| Comparison of effects of dexmedetomidine-ketamine and dexmedetomidine-midazolam combinations in transurethral procedures. | Urology 20120601 |
| [Effect of dexmedetomidine on stress responses during extubation in patients undergoing uvulopalatopharyngoplasty]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20120601 |
| [Dexmedetomidine for sedation of post liver transplantation patients]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20120601 |
| Dexmedetomidine administration before, but not after, ischemia attenuates intestinal injury induced by intestinal ischemia-reperfusion in rats. | Anesthesiology 20120501 |
| Effect of medetomidine-butorphanol and dexmedetomidine-butorphanol combinations on intraocular pressure in healthy dogs. | Veterinary anaesthesia and analgesia 20120501 |
| The efficacy of continuous infusion of low dose dexmedetomidine for postoperative patients recovering in general wards. | European journal of anaesthesiology 20120501 |
| Hemodynamic impact of dexmedetomidine administration in 15,656 noncardiac surgical cases. | Journal of clinical anesthesia 20120501 |
| Effects of isoflurane anesthesia with and without dexmedetomidine or remifentanil on quantitative electroencephalographic variables before and after nociceptive stimulation in dogs. | American journal of veterinary research 20120501 |
| [Evaluation of the sedative effect of dexmedetomidine on patients after surgical occlusion of ruptured cerebral aneurysm in intensive care unit]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20120501 |
| [Dexmedetomidine is an excellent sedative for voice monitoring surgery]. | Masui. The Japanese journal of anesthesiology 20120501 |
| Questions about dexmedetomidine as a preanesthetic in cats. | Journal of the American Veterinary Medical Association 20120415 |
| [Effect of dexmedetomidine on postoperative analgesia and sedation in pediatric patients undergoing cleft lip and palate repair]. | Zhonghua yi xue za zhi 20120403 |
| Effect of dexmedetomidine on the minimum alveolar concentration of isoflurane in cats. | Journal of veterinary pharmacology and therapeutics 20120401 |
| Intravenous dexmedetomidine for treatment of intraoperative penile erection. | International urology and nephrology 20120401 |
| Comparison of the effects of fentanyl, remifentanil, and dexmedetomidine on neuromuscular blockade. | Journal of anesthesia 20120401 |
| Comparison between propofol and dexmedetomidine in postoperative sedation after extensive cervical spine surgery. | Journal of anesthesia 20120401 |
| A high dose of dexmedetomidine using the BIS monitor™ for diagnostic and interventional cardiac catheterization in a toddler with congenital heart disease. | Journal of anesthesia 20120401 |
| Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart. | Biochimica et biophysica acta 20120401 |
| Weaning from mechanical ventilation and sedation. | Current opinion in anaesthesiology 20120401 |
| Stability of dexmedetomidine 4 μg/mL in polypropylene syringes. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120401 |
| Dose-response and mechanism of protective functions of selective alpha-2 agonist dexmedetomidine on acute lung injury in rats. | Saudi medical journal 20120401 |
| [Dexmedetomidine for postoperative sedation in elderly patients with cognitive impairment]. | Masui. The Japanese journal of anesthesiology 20120401 |
| Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. | JAMA 20120321 |
| Weighing the costs and benefits of a sedative. | JAMA 20120321 |
| Dexmedetomidine prevents remifentanil-induced postoperative hyperalgesia and decreases spinal tyrosine phosphorylation of N-methyl-d-aspartate receptor 2B subunit. | Brain research bulletin 20120310 |
| Effects of intravenous administration of dexmedetomidine on intraocular pressure and pupil size in clinically normal dogs. | Veterinary ophthalmology 20120301 |
| Influence of MK-467, a peripherally acting α2-adrenoceptor antagonist on the disposition of intravenous dexmedetomidine in dogs. | Drug metabolism and disposition: the biological fate of chemicals 20120301 |
| Randomized double-blind study of remifentanil and dexmedetomidine for flexible bronchoscopy. | British journal of anaesthesia 20120301 |
| Effects of intravenous dexmedetomidine on low-dose bupivacaine spinal anaesthesia in elderly patients. | Acta anaesthesiologica Scandinavica 20120301 |
| Population pharmacokinetics of dexmedetomidine during long-term sedation in intensive care patients. | British journal of anaesthesia 20120301 |
| Dexmedetomidine reduces the incidence of fentanyl-induced cough: a double-blind, randomized, and placebo-controlled study. | Upsala journal of medical sciences 20120301 |
| Sedative, cardiovascular, haematologic and biochemical effects of four different drug combinations administered intramuscularly in cats. | Veterinary anaesthesia and analgesia 20120301 |
| Dexmedetomidine sedation: uses in pediatric procedural sedation outside the operating room. | Pediatric emergency care 20120301 |
| Dexmedetomidine for the treatment of severe postoperative functional stridor. | Anaesthesia and intensive care 20120301 |
| Comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during coblation-assisted upper airway procedure. | Chinese medical journal 20120301 |
| The relationship between dexmedetomidine dosing and hypotension. | The journal of trauma and acute care surgery 20120301 |
| Is dexmedetomidine the agent of choice in the resection of pheochromocytoma? | The American surgeon 20120301 |
| Dexmedetomidine compare with fentanyl for postoperative analgesia in outpatient gynecologic laparoscopy: a randomized controlled trial. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20120301 |
| [Clonidine and dexmedetomidine's effect on the altered expressions of growth associated protein-43 mRNA in rat dorsal root ganglion during the development of chronic neuropathic pain]. | Zhonghua yi xue za zhi 20120221 |
| Clinical efficacy and safety of dexmedetomidine used as a preanesthetic prior to general anesthesia in cats. | Journal of the American Veterinary Medical Association 20120215 |
| Dexmedetomidine directly inhibits vascular ATP-sensitive potassium channels. | Life sciences 20120213 |
| Weaning from mechanical ventilation. | Current opinion in anaesthesiology 20120201 |
| Discontinuation of prolonged infusions of dexmedetomidine in critically ill children with heart disease. | Intensive care medicine 20120201 |
| Pediatric sedation in a community hospital-based outpatient MRI center. | AJR. American journal of roentgenology 20120201 |
| [Sedation concepts in intensive care]. | Deutsche medizinische Wochenschrift (1946) 20120201 |
| Pharmacokinetics of dexmedetomidine administered intravenously in isoflurane-anesthetized cats. | American journal of veterinary research 20120201 |
| Use of dexmedetomidine and ketamine in combination with opioids. | Journal of the American Veterinary Medical Association 20120201 |
| Use of dexmedetomidine and ketamine in combination with opioids. | Journal of the American Veterinary Medical Association 20120201 |
| Occurrence and predictors of dexmedetomidine infusion intolerance and failure. | Hospital practice (1995) 20120201 |
| Dexmedetomidine and clonidine induce long-lasting activation of the respiratory rhythm generator of neonatal mice: possible implication for critical care. | Respiratory physiology & neurobiology 20120115 |
| Inhibition by dexmedetomidine of the activation of spinal dorsal horn glias and the intracellular ERK signaling pathway induced by nerve injury. | Brain research 20120103 |
| Dexmedetomidine and clonidine: from second- to first-line sedative agents in the critical care setting? | Journal of intensive care medicine 20120101 |
| Cardiovascular effects of dexmedetomidine sedation in children. | Anesthesia and analgesia 20120101 |
| Suspected opioid-induced hyperalgesia in an infant. | British journal of anaesthesia 20120101 |
| Dexmedetomidine protects against oxygen-glucose deprivation-induced injury through the I2 imidazoline receptor-PI3K/AKT pathway in rat C6 glioma cells. | The Journal of pharmacy and pharmacology 20120101 |
| Influence of a constant rate infusion of dexmedetomidine on cardiopulmonary function and recovery quality in isoflurane anaesthetized horses. | Veterinary anaesthesia and analgesia 20120101 |
| Comparison of the effects of ketamine-dexmedetomidine and sevoflurane-sufentanil anesthesia on cardiac biomarkers after cardiac surgery: an observational study. | Physiological research 20120101 |
| The effects of dexmedetomidine on attenuation of stress response to endotracheal intubation in patients undergoing elective off-pump coronary artery bypass grafting. | Annals of cardiac anaesthesia 20120101 |
| Dexmedetomidine: current role in anesthesia and intensive care. | Revista brasileira de anestesiologia 20120101 |
| Pharmacological and nonpharmacological management of delirium in critically ill patients. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20120101 |
| Prevention, recognition, and management of delirium in the intensive care unit. | AACN advanced critical care 20120101 |
| Comparison of sedative drugs under peribulbar or topical anesthesia during phacoemulsification. | Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20120101 |
| Does vitamin C prevent the effects of high dose dexmedetomidine on rat erythrocyte deformability? | Bratislavske lekarske listy 20120101 |
| Cigarette smoking and the effect of dexmedetomidine and fentanyl on tracheal intubation. | Revista brasileira de anestesiologia 20120101 |
| A review of pharmacologic management and prevention strategies for delirium in the intensive care unit. | Psychosomatics 20120101 |
| Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury. | BMC neurology 20120101 |
| The effects of low-high doses of dexmedetomidine on erythrocyte deformability in rats. | Bratislavske lekarske listy 20120101 |
| Dexmedetomidine in pediatric cardiac anesthesia. | Annals of cardiac anaesthesia 20120101 |
| Dexmedetomidine controls junctional ectopic tachycardia during Tetralogy of Fallot repair in an infant. | Annals of cardiac anaesthesia 20120101 |
| Dexmedetomidine and clonidine inhibit ventricular tachyarrhythmias in a rabbit model of acquired long QT syndrome. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Dexmedetomidine and its increasing application in nonopioid detoxification. | Journal of opioid management 20120101 |
| Transcatheter aortic valve replacement under monitored anesthesia care versus general anesthesia with intubation. | Cardiovascular revascularization medicine : including molecular interventions 20120101 |
| A comparison of dexmedetomidine sedation with and without midazolam for dental implant surgery. | Anesthesia progress 20120101 |
| Efficacy of intrathecally administered dexmedetomidine versus dexmedetomidine with fentanyl in patients undergoing major abdominal cancer surgery. | Pain physician 20120101 |
| Dexmedetomidine versus midazolam for conscious sedation in postoperative patients undergoing flexible bronchoscopy: a randomized study. | The Journal of international medical research 20120101 |
| Dexmedetomidine versus midazolam for the sedation of patients with non-invasive ventilation failure. | Internal medicine (Tokyo, Japan) 20120101 |
| Correlation between bispectral index, observational sedation scale, and lower esophageal sphincter pressure in volunteers using dexmedetomidine or propofol. | Medical science monitor : international medical journal of experimental and clinical research 20120101 |
| Neurophysiological assessment of the sedative and analgesic effects of a constant rate infusion of dexmedetomidine in the dog. | Veterinary journal (London, England : 1997) 20111201 |
| Dexmedetomidine can stabilize hemodynamics and spare anesthetics before cardiopulmonary bypass. | Journal of anesthesia 20111201 |
| Dexmedetomidine: applications for the pediatric patient with congenital heart disease. | Pediatric cardiology 20111201 |
| Perioperative infusion of dexmedetomidine at a high dose reduces postoperative analgesic requirements: a randomized control trial. | Journal of anesthesia 20111201 |
| Consciousness lost and found: subjective experiences in an unresponsive state. | Brain and cognition 20111201 |
| Apparent dexmedetomidine-induced polyuric syndrome in an achondroplastic patient undergoing posterior spinal fusion. | Anesthesia and analgesia 20111201 |
| Use of dexmedetomidine to discontinue high-dose fentanyl. | The Annals of pharmacotherapy 20111201 |
| Consciousness versus responsiveness: insights from general anesthetics. | Brain and cognition 20111201 |
| Evaluation of dexmedetomidine and ketamine in combination with various opioids as injectable anesthetic combinations for castration in cats. | Journal of the American Veterinary Medical Association 20111201 |
| Dexmedetomidine controls twitch-convulsive syndrome in the course of uremic encephalopathy. | Journal of clinical anesthesia 20111201 |
| Incidence of cardiac arrest increases with the indiscriminate use of dexmedetomidine: a case series and review of published case reports. | Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20111201 |
| Bronchial thermoplasty: a novel treatment for severe asthma requiring monitored anesthesia care. | AANA journal 20111201 |
| Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals by α2 adrenoceptor agonist dexmedetomidine. | European journal of pharmacology 20111116 |
| Evaluation of dexmedetomidine: safety and clinical outcomes in critically ill trauma patients. | The Journal of trauma 20111101 |
| The effect of dexmedetomidine during myringotomy and pressure-equalizing tube placement in children. | Paediatric anaesthesia 20111101 |
| Children with anterior mediastinal mass: procedural sedation with dexmedetomidine. | European journal of anaesthesiology 20111101 |
| Review article: Dexmedetomidine in children: current knowledge and future applications. | Anesthesia and analgesia 20111101 |
| Postoperative respiratory and analgesic effects of dexmedetomidine or morphine for adenotonsillectomy in children with obstructive sleep apnoea. | Anaesthesia 20111101 |
| Impact of intraoperative dexmedetomidine on postoperative analgesia following gynecologic surgery. | Current medical research and opinion 20111101 |
| Effects of alpha 2-adrenoceptor agonists dexmedetomidine and guanfacine on morphine analgesia and tolerance in rats. | Upsala journal of medical sciences 20111101 |
| Hemodynamic effects of dexmedetomidine in isoflurane-anesthetized cats. | Veterinary anaesthesia and analgesia 20111101 |
| Regional anesthesia in anticoagulated patients. | Journal of clinical anesthesia 20111101 |
| Postpartum analgesia with dexmedetomidine in opioid tolerance during pregnancy. | Journal of clinical anesthesia 20111101 |
| Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice. | Acta anaesthesiologica Scandinavica 20111101 |
| [Clinical observation of injection of dexmedetomidine in anaesthesia for esophageal cancer operation]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20111101 |
| Perineural dexmedetomidine added to ropivacaine for sciatic nerve block in rats prolongs the duration of analgesia by blocking the hyperpolarization-activated cation current. | Anesthesiology 20111001 |
| Epidural anesthesia with intravenous dexmedetomidine sedation in the successful anesthetic management of MRI-guided focused ultrasound ablation of early prostatic cancer. | Journal of anesthesia 20111001 |
| Wide inter-individual variability of bispectral index and spectral entropy at loss of consciousness during increasing concentrations of dexmedetomidine, propofol, and sevoflurane. | British journal of anaesthesia 20111001 |
| A Bayesian hierarchical nonlinear mixture model in the presence of artifactual outliers in a population pharmacokinetic study. | Journal of pharmacokinetics and pharmacodynamics 20111001 |
| Interaction between dexmedetomidine and α-adrenergic receptors: emphasis on vascular actions. | Journal of cardiothoracic and vascular anesthesia 20111001 |
| Postoperative delirium. part 2: detection, prevention and treatment. | European journal of anaesthesiology 20111001 |
| Prospective, randomized study to assess the role of dexmedetomidine in patients with supratentorial tumors undergoing craniotomy under general anaesthesia. | Middle East journal of anaesthesiology 20111001 |
| Analgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia. | British journal of anaesthesia 20110901 |
| Dexmedetomidine for co-analgesia in chemotherapy-induced severe enterocolitis. | Paediatric anaesthesia 20110901 |
| Effects of different doses of L-659'066 on the bispectral index and clinical sedation in dogs treated with dexmedetomidine. | Veterinary anaesthesia and analgesia 20110901 |
| Sedation and anesthesia issues in pediatric imaging. | Pediatric radiology 20110901 |
| Intramuscular dexmedetomidine sedation for pediatric MRI and CT. | AJR. American journal of roentgenology 20110901 |
| Perioperative use of dexmedetomidine is associated with decreased incidence of ventricular and supraventricular tachyarrhythmias after congenital cardiac operations. | The Annals of thoracic surgery 20110901 |
| [Comparison of sedative effect of dexmedetomidine and midazolam for post-operative patients undergoing mechanical ventilation in surgical intensive care unit]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20110901 |
| Evaluation of outcomes in patients given dexmedetomidine in functional endoscopic sinus surgery. | The Annals of otology, rhinology, and laryngology 20110901 |
| Dexmedetomidine controls agitation and facilitates reliable, serial neurological examinations in a non-intubated patient with traumatic brain injury. | Neurocritical care 20110801 |
| The effects of increasing doses of MK-467, a peripheral alpha(2)-adrenergic receptor antagonist, on the cardiopulmonary effects of intravenous dexmedetomidine in conscious dogs. | Journal of veterinary pharmacology and therapeutics 20110801 |
| Effects of different doses of remifentanil infusion on hemodynamics and recovery in children undergoing pediatric diagnostic cardiac catheterization. | Journal of cardiothoracic and vascular anesthesia 20110801 |
| Bioavailability of dexmedetomidine after intranasal administration. | European journal of clinical pharmacology 20110801 |
| Multicenter assessment of the Iowa Satisfaction with Anesthesia Scale, an instrument that measures patient satisfaction with monitored anesthesia care. | Anesthesia and analgesia 20110801 |
| Dexmedetomidine as sole agent for awake fiberoptic intubation in a patient with local anesthetic allergy. | Journal of anesthesia 20110801 |
| The effects of dexmedetomidine on regional cerebral blood flow and oxygen consumption during severe hemorrhagic hypotension in rats. | Anesthesia and analgesia 20110801 |
| Administration of dexmedetomidine alone during diagnostic cardiac catheterization in adults with congenital heart disease: two case reports. | Journal of anesthesia 20110801 |
| Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells. | Journal of anesthesia 20110801 |
| [Postoperative analgesia of continuous intravenous fentanyl or dexmedetomidine for patients receiving anticoagulant therapy]. | Masui. The Japanese journal of anesthesiology 20110801 |
| Dexmedetomidine: a review of its use for sedation in mechanically ventilated patients in an intensive care setting and for procedural sedation. | Drugs 20110730 |
| [Application of sedation with a low dose of dexmedetomidine during intrathecal anesthesia in elderly patients]. | Zhonghua yi xue za zhi 20110726 |
| Takotsubo cardiomyopathy and the difficult airway. | Journal of neurosurgical anesthesiology 20110701 |
| Limb-specific differences in the skin vascular responsiveness to adrenergic agonists. | Journal of applied physiology (Bethesda, Md. : 1985) 20110701 |
| Pediatric sedation--evolution and revolution. | Paediatric anaesthesia 20110701 |
| A randomized, blinded, controlled trial of the antiemetic effect of ondansetron on dexmedetomidine-induced emesis in cats. | Veterinary anaesthesia and analgesia 20110701 |
| Dexmedetomidine for opioid and benzodiazepine withdrawal in pediatric patients. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110701 |
| Evaluation of the sedative and cardiovascular effects of intramuscular administration of dexmedetomidine with and without concurrent atropine administration in dogs. | Journal of the American Veterinary Medical Association 20110701 |
| Dexmedetomidine for the prevention of shivering during spinal anesthesia. | Clinics (Sao Paulo, Brazil) 20110701 |
| Effect of a dexmedetomidine substitution during a nationwide propofol shortage in patients undergoing coronary artery bypass graft surgery. | Pharmacotherapy 20110701 |
| Sedation for radiological imaging. | Archives of disease in childhood. Education and practice edition 20110601 |
| The role of the ADRA2A C1291G genetic polymorphism in response to dexmedetomidine on patients undergoing coronary artery surgery. | Molecular biology reports 20110601 |
| Review article: dexmedetomidine: does it have potential in palliative medicine? | The American journal of hospice & palliative care 20110601 |
| Prevention of shivering during therapeutic temperature modulation: the Columbia anti-shivering protocol. | Neurocritical care 20110601 |
| Evaluation of the analgesic efficacy of local dexmedetomidine application. | The Clinical journal of pain 20110601 |
| Delirium and sedation in the ICU. | Neurocritical care 20110601 |
| Analgosedation in neonates: do we still need additional tools after 30 years of clinical research? | Archives of disease in childhood. Education and practice edition 20110601 |
| Dexmedetomidine sedation for awake fiberoptic intubation of patients with difficult airways due to severe odontogenic cervicofacial infections. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20110601 |
| Dexmedetomidine: an alternative for epidural anesthesia in tension-free vaginal-tape surgery. | Journal of anesthesia 20110601 |
| Volatile agents for ICU sedation? | Intensive care medicine 20110601 |
| High-dose dexmedetomidine increases the opioid-free interval and decreases opioid requirement after tonsillectomy in children. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20110601 |
| Dexmedetomidine and S(+)-ketamine in ischemia and reperfusion injury in the rat kidney. | Acta cirurgica brasileira 20110601 |
| High-dose dexmedetomidine for sedation in the intensive care unit: an evaluation of clinical efficacy and safety. | The Annals of pharmacotherapy 20110601 |
| Dexmedetomidine as a pediatric anesthetic premedication to reduce anxiety and to deter emergence delirium. | AANA journal 20110601 |
| Dexmedetomidine (Precedex) for ICU sedation. | The Medical letter on drugs and therapeutics 20110530 |
| Protective effects of dexmedetomidine-ketamine combination against ventilator-induced lung injury in endotoxemia rats. | The Journal of surgical research 20110515 |
| Modulation of postjunctional α-adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans. | The Journal of physiology 20110515 |
| Hemodynamics in coronary artery bypass surgery: effects of intraoperative dexmedetomidine administration. | Der Anaesthesist 20110501 |
| c-Jun NH₂-terminal kinase contributes to dexmedetomidine-induced contraction in isolated rat aortic smooth muscle. | Yonsei medical journal 20110501 |
| Role of α2-agonists in the treatment of acute alcohol withdrawal. | The Annals of pharmacotherapy 20110501 |
| Evaluation of dexmedetomidine and ketamine in combination with opioids as injectable anesthesia for castration in dogs. | Journal of the American Veterinary Medical Association 20110501 |
| Hemodynamic characteristics of midazolam, propofol, and dexmedetomidine in healthy volunteers. | Journal of clinical anesthesia 20110501 |
| Dexmedetomidine and procedural sedation: the AusPAR a TGA resource. | Anaesthesia and intensive care 20110501 |
| The effects of intraoperative infusion of dexmedetomidine on early renal function after percutaneous nephrolithotomy. | Acta anaesthesiologica Scandinavica 20110501 |
| Dexmedetomidine protects blood δ-aminolevulinate dehydratase from inactivation caused by hyperoxygenation in total intravenous anesthesia. | Human & experimental toxicology 20110401 |
| A randomized, controlled trial on dexmedetomidine for providing adequate sedation and hemodynamic control for awake, diagnostic transesophageal echocardiography. | Journal of cardiothoracic and vascular anesthesia 20110401 |
| Post-operative dexmedetomidine-based sedation after uneventful intracranial surgery for unruptured cerebral aneurysm: comparison with propofol-based sedation. | Neurocritical care 20110401 |
| Effects of dexmedetomidine on the release of glial cell line-derived neurotrophic factor from rat astrocyte cells. | Neurochemistry international 20110401 |
| Successful implementation of a pediatric sedation protocol for mechanically ventilated patients. | Critical care medicine 20110401 |
| Dexmedetomidine inhibits gastric emptying and oro-caecal transit in healthy volunteers. | British journal of anaesthesia 20110401 |
| Impact of dexmedetomidine on early extubation in pediatric cardiac surgical patients. | Intensive care medicine 20110401 |
| Genetic variations in the α(2A)-adrenoreceptor are associated with blood pressure response to the agonist dexmedetomidine. | Circulation. Cardiovascular genetics 20110401 |
| Oral melatonin, dexmedetomidine, and midazolam for prevention of postoperative agitation in children. | Journal of anesthesia 20110401 |
| The comparison of the effects of dexmedetomidine and midazolam sedation on electroencephalography in pediatric patients with febrile convulsion. | Paediatric anaesthesia 20110401 |
| Sedation with dexmedetomidine hydrochloride during endoscopic submucosal dissection of gastric cancer. | Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 20110401 |
| When the decision is what to decide: using evidence inventory reports to focus health technology assessments. | International journal of technology assessment in health care 20110401 |
| [Effect of dexmedetomidine on patient-controlled intravenous analgesia with fentanyl in elderly patients after total hip replacement]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110401 |
| [Measurement of the minimum alveolar concentration of sevoflurane during combined anesthesia with sevoflurane, small-dose dexmedetomidine and fentanyl]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110401 |
| [Determination of the 50% effective concentration of dexmedetomidine as an adjuvant in combined spinal-epidural anesthesia with Narcotrend]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110401 |
| [The effect of dexmedetomidine in a child with intractable supraventricular tachyarrythmia after total cavopulmonary connection]. | Masui. The Japanese journal of anesthesiology 20110401 |
| Dexmedetomidine in cardiac surgery patients who fail extubation and present with a delirium state. | The heart surgery forum 20110401 |
| Use of dexmedetomidine and ketamine infusions during scoliosis repair surgery with somatosensory and motor-evoked potential monitoring: a case report. | AANA journal 20110401 |
| Efficacy and safety of dexmedetomidine versus morphine in post-operative cardiac surgery patients. | International journal of clinical pharmacy 20110401 |
| Dexmedetomidine as an adjuvant analgesic for intractable cancer pain. | Journal of palliative medicine 20110301 |
| Pharmacokinetics of dexmedetomidine in Chinese post-surgical intensive care unit patients. | Acta anaesthesiologica Scandinavica 20110301 |
| Evaluation of medetomidine-ketamine and dexmedetomidine-ketamine in Chinese water deer (Hydropotes inermis). | Veterinary anaesthesia and analgesia 20110301 |
| Dorsal hand vein responses to the α₁-adrenoceptor agonist phenylephrine do not predict responses to the α₂-adrenoceptor agonist dexmedetomidine. | European journal of pharmacology 20110225 |
| Independent regulation of α1 and α2 adrenergic receptor-mediated vasoconstriction in vivo. | Journal of hypertension 20110201 |
| High-dose dexmedetomidine sedation for pediatric MRI. | Paediatric anaesthesia 20110201 |
| Pediatric CT sedation: comparison of dexmedetomidine and pentobarbital. | AJR. American journal of roentgenology 20110201 |
| Dexmedetomidine use in pediatric airway reconstruction. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20110201 |
| Prospective, randomized controlled study to assess the role of dexmedetomidine in patients with supratentorial tumors undergoing craniotomy under general anesthesia. | Middle East journal of anaesthesiology 20110201 |
| Dexmedetomidine premedication of outpatients under IVRA. | Middle East journal of anaesthesiology 20110201 |
| Dexmedetomidine controls the hemodynamic manifestations of tourniquet pain. | American journal of therapeutics 20110101 |
| Dexmedetomidine: pediatric pharmacology, clinical uses and safety. | Expert opinion on drug safety 20110101 |
| Dexmedetomidine: new insights. | European journal of anaesthesiology 20110101 |
| Dexmedetomidine-related atrial standstill and loss of capture in a pediatric patient after congenital heart surgery. | Critical care medicine 20110101 |
| Use of dexmedetomidine for sedation in critically ill mechanically ventilated pediatric burn patients. | Journal of burn care & research : official publication of the American Burn Association 20110101 |
| Angiotensin-converting enzyme inhibitor - An innocuous factor behind cardiac arrest following induction of anesthesia. | Annals of cardiac anaesthesia 20110101 |
| Two doses of dexmedetomidine in combination with buprenorphine for premedication in dogs; a comparison with acepromazine and buprenorphine. | Veterinary anaesthesia and analgesia 20110101 |
| [Dexmedetomidine for endoscopic submucosal dissection in a patient with severe chronic obstructive pulmonary disease]. | Masui. The Japanese journal of anesthesiology 20110101 |
| Dexmedetomidine and procedural sedation. | Anaesthesia and intensive care 20110101 |
| Antiulcerative effect of dexmedetomidine on indomethacin-induced gastric ulcer in rats. | Pharmacological reports : PR 20110101 |
| Anesthetic management for combined mitral valve replacement and aortic valve repair in a patient with osteogenesis imperfecta. | Annals of cardiac anaesthesia 20110101 |
| Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice. | Critical care (London, England) 20110101 |
| Dexmedetomidine use during strabismus surgery in agitated children. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20110101 |
| Integrative review utilizing dexmedetomidine as an anesthetic for monitored anesthesia care and regional anesthesia. | Nursing forum 20110101 |
| Ephedrine enhances the antinociceptive effect of dexmedetomidine in mice. | Neuro endocrinology letters 20110101 |
| Additives to local anesthetics for peripheral nerve blockade. | International anesthesiology clinics 20110101 |
| Pharmacokinetics of prolonged infusion of high-dose dexmedetomidine in critically ill patients. | Critical care (London, England) 20110101 |
| Comparison of an intraoperative infusion of dexmedetomidine or remifentanil on perioperative haemodynamics, hypnosis and sedation, and postoperative pain control. | The Journal of international medical research 20110101 |
| Ultra-rapid opiate detoxification using dexmedetomidine under general anesthesia. | Journal of opioid management 20110101 |
| Successful treatment of acute mania and perineal abscess using dexmedetomidine sedation as adjunctive therapy. | BMJ case reports 20110101 |
| Premedication with dexmedetomidine alone or together with 0.5% lidocaine for IVRA. | The Journal of surgical research 20101201 |
| Successful treatment of ifosfamide neurotoxicity with dexmedetomidine. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20101201 |
| Management of a tumor in the distal trachea while maintaining spontaneous ventilation. | Journal of anesthesia 20101201 |
| Dexmedetomidine versus fentanyl as adjuvant to propofol: comparative study in children undergoing extracorporeal shock wave lithotripsy. | European journal of anaesthesiology 20101201 |
| Deterioration of myocardial injury due to dexmedetomidine administration after myocardial ischaemia. | Resuscitation 20101201 |
| Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat. | The Journal of pharmacology and experimental therapeutics 20101201 |
| Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients. | Critical care medicine 20101201 |
| Dexmedetomidine added to levobupivacaine prolongs axillary brachial plexus block. | Anesthesia and analgesia 20101201 |
| Dexmedetomidine-ketamine and midazolam-ketamine combinations for sedation in pediatric patients undergoing extracorporeal shock wave lithotripsy: a randomized prospective study. | Journal of anesthesia 20101201 |
| Dexmedetomidine infusion for the management of opioid-induced hyperalgesia. | Pain medicine (Malden, Mass.) 20101201 |
| Systemic daily morphine enhances the analgesic effect of intrathecal dexmedetomidine via up-regulation of alpha 2 adrenergic receptor subtypes A, B and C in dorsal root ganglion and dorsal horn. | The Journal of pharmacy and pharmacology 20101201 |
| Acute hemodynamic changes after rapid intravenous bolus dosing of dexmedetomidine in pediatric heart transplant patients undergoing routine cardiac catheterization. | Anesthesia and analgesia 20101201 |
| Dexmedetomidine: clinical application as an adjunct for intravenous regional anesthesia. | Anesthesiology clinics 20101201 |
| All this confusion is killin' me. | Critical care medicine 20101201 |
| Dexmedetomidine was safely used for sedation during spinal anesthesia in a very elderly patient. | Journal of anesthesia 20101201 |
| Evaluation of dexmedetomidine versus propofol-based sedation therapy in mechanically ventilated cardiac surgery patients at a tertiary academic medical center. | Critical pathways in cardiology 20101201 |
| Dexmedetomidine: exploring its potential role and dosing guideline for its use in intractable pain in the palliative care setting. | Journal of pain & palliative care pharmacotherapy 20101201 |
| Use of dexmedetomidine and ketamine infusions during scoliosis repair surgery with somatosensory and motor-evoked potential monitoring: a case report. | AANA journal 20101201 |
| Efficacy of intra-articular dexmedetomidine for postoperative analgesia in arthroscopic knee surgery. | The Ceylon medical journal 20101201 |
| Voiding effects mediated by α2-adrenoceptors in the anaesthetized male rat. | BJU international 20101101 |
| Patient-controlled sedation: a novel approach to sedation management for mechanically ventilated patients. | Chest 20101101 |
| Astrocytic transactivation by alpha2A-adrenergic and 5-HT2B serotonergic signaling. | Neurochemistry international 20101101 |
| Comparison of local anaesthesia with dexmedetomidine sedation and general anaesthesia during septoplasty. | European journal of anaesthesiology 20101101 |
| Comment on dexmedetomidine systematic review and meta-analysis methodology. | Intensive care medicine 20101101 |
| Midazolam enhances the analgesic properties of dexmedetomidine in the rat. | Veterinary anaesthesia and analgesia 20101101 |
| Dexmedetomidine and ketamine for sedation during spinal anesthesia in children. | Journal of clinical anesthesia 20101101 |
| [Some adjuvants added to local anesthetics improve the duration and quality of epidural anesthesia]. | Masui. The Japanese journal of anesthesiology 20101101 |
| Effect of single-dose dexmedetomidine on emergence agitation and recovery profiles after sevoflurane anesthesia in pediatric ambulatory surgery. | Journal of anesthesia 20101001 |
| Awake intubation under sedation using target-controlled infusion of dexmedetomidine: five case reports. | Journal of anesthesia 20101001 |
| Brain tissue oxygenation during dexmedetomidine administration in surgical patients with neurovascular injuries. | Journal of neurosurgical anesthesiology 20101001 |
| Evidence for suppression of spinal glial activation by dexmedetomidine in a rat model of monoarthritis. | Clinical and experimental pharmacology & physiology 20101001 |
| Dexmedetomidine infusion for analgesia and prevention of emergence agitation in children with obstructive sleep apnea syndrome undergoing tonsillectomy and adenoidectomy. | Anesthesia and analgesia 20101001 |
| The effects of L-659,066, a peripheral α2-adrenoceptor antagonist, and verapamil on the cardiovascular influences of dexmedetomidine in conscious sheep. | Journal of veterinary pharmacology and therapeutics 20101001 |
| Patient agitation and dexmedetomidine. | The Nurse practitioner 20101001 |
| [The role of dexmedetomidine in treatment of serious patients in intensive care unit]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20101001 |
| [The use of dexmedetomidine hydrochloride in intensive care unit]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20101001 |
| Effect of dexmedetomidine on pulmonary artery pressure after congenital cardiac surgery: A pilot study. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20100901 |
| Cognitive improvement during continuous sedation in critically ill, awake and responsive patients: the Acute Neurological ICU Sedation Trial (ANIST). | Intensive care medicine 20100901 |
| Dexmedetomidine for awake fibreoptic intubation and awake self-positioning in a patient with a critically located cervical lesion for surgical removal of infra-tentorial tumour. | Anaesthesia 20100901 |
| Optimal timing for the administration of intranasal dexmedetomidine for premedication in children. | Anaesthesia 20100901 |
| Sedative and cardiorespiratory effects of dexmedetomidine and buprenorphine administered to cats via oral transmucosal or intramuscular routes. | Veterinary anaesthesia and analgesia 20100901 |
| Ultrasound-guided nerve blocks of the pelvic limb in dogs. | Veterinary anaesthesia and analgesia 20100901 |
| Dexmedetomidine and pulmonary artery pressure in the pediatric cardiac surgery patient--A new insight. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20100901 |
| Dexmedetomidine as a postoperative sedative after congenital cardiac surgery--Consideration of the anesthetic management has an important role. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20100901 |
| Dexmedetomidine-ketamine combination mitigates pulmonary type-2 cationic amino acid transporter isozymes upregulation in hemorrhagic shock rats. | Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20100901 |
| Dexmedetomidine for anesthetic management of anterior mediastinal mass. | Journal of anesthesia 20100801 |
| Monitored anesthesia care with dexmedetomidine of a patient with severe pulmonary arterial hypertension for inguinal hernioplasty. | Journal of anesthesia 20100801 |
| The effects of intravenous dexmedetomidine on spinal hyperbaric ropivacaine anesthesia. | Journal of anesthesia 20100801 |
| Anaesthesia or sedation for MRI in children. | Current opinion in anaesthesiology 20100801 |
| The effect of intraoperative dexmedetomidine on postoperative analgesia and sedation in pediatric patients undergoing tonsillectomy and adenoidectomy. | Anesthesia and analgesia 20100801 |
| Dexmedetomidine in the care of critically ill patients from 2001 to 2007: an observational cohort study. | Anesthesiology 20100801 |
| High concentrations of dexmedetomidine inhibit compound action potentials in frog sciatic nerves without alpha(2) adrenoceptor activation. | British journal of pharmacology 20100801 |
| Dexmedetomidine sedation for awake tracheotomy: case report and literature review. | Journal of clinical anesthesia 20100801 |
| Prolonged infusions of dexmedetomidine in critically ill patients. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100801 |
| Pharmacologic options for reducing the shivering response to therapeutic hypothermia. | Pharmacotherapy 20100801 |
| [Two cases of cervical carotid artery stenosis with high risk post-operative hyperperfusion treated with dexmedetomidine after carotid endarterectomy]. | No shinkei geka. Neurological surgery 20100801 |
| Considerations for the use of anesthetics in neurotoxicity studies. | Comparative medicine 20100801 |
| Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain. | Acta anaesthesiologica Scandinavica 20100701 |
| Effect of epidural dexmedetomidine on intraoperative awareness and post-operative pain after one-lung ventilation. | Acta anaesthesiologica Scandinavica 20100701 |
| A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation. | European journal of anaesthesiology 20100701 |
| Cardiopulmonary effects of two constant rate infusions of dexmedetomidine in isoflurane anaesthetized ponies. | Veterinary anaesthesia and analgesia 20100701 |
| Use of dexmedetomidine in sustained ventricular tachycardia. | Anaesthesia and intensive care 20100701 |
| [The effect of perioperative infused dexmedetomidine on postoperative analgesic consumption in mastoidectomy operations]. | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20100701 |
| [Comparison of the activity and reliability of intravenous administration of midazolam and dexmedetomidine on sedation levels under epidural anesthesia]. | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20100701 |
| Dexmedetomidine and the successful management of electroconvulsive therapy postictal agitation: a case report. | The journal of ECT 20100601 |
| Pain relief during dressing changes of major adult burns: ideal analgesic combination with ketamine. | Burns : journal of the International Society for Burn Injuries 20100601 |
| Evaluating the use of dexmedetomidine in neurocritical care patients. | Neurocritical care 20100601 |
| Use of dexmedetomidine as a sedative and analgesic agent in critically ill adult patients: a meta-analysis. | Intensive care medicine 20100601 |
| The effects of dexmedetomidine dosage on cerebral vasospasm in a rat subarachnoid haemorrhage model. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100601 |
| Effect of increasing depth of dexmedetomidine anesthesia on upper airway morphology in children. | Paediatric anaesthesia 20100601 |
| Incidence and predictors of hypertension during high-dose dexmedetomidine sedation for pediatric MRI. | Paediatric anaesthesia 20100601 |
| Susceptibility of transcranial electric motor-evoked potentials to varying targeted blood levels of dexmedetomidine during spine surgery. | Anesthesiology 20100601 |
| Intensive care unit delirium. | Critical care nursing clinics of North America 20100601 |
| The role of the alpha 2A-adrenoceptor in mouse stress-coping behaviour. | Psychoneuroendocrinology 20100501 |
| Electrocardiographic effects of dexmedetomidine in patients with congenital heart disease. | Intensive care medicine 20100501 |
| Comparison of three anaesthetic protocols in Bennett's wallabies (Macropus rufogriseus). | Veterinary anaesthesia and analgesia 20100501 |
| A prospective, randomized, placebo-controlled study evaluating the efficacy of dexmedetomidine for sedation during vascular procedures. | Vascular and endovascular surgery 20100501 |
| Dexmedetomidine hemodynamics in children after cardiac surgery. | Paediatric anaesthesia 20100501 |
| Dexmedetomidine blocks thermal hyperalgesia and spinal glial activation in rat model of monoarthritis. | Acta pharmacologica Sinica 20100501 |
| Combination of high-dose dexmedetomidine sedation and fascia iliaca compartment block for hip fracture surgery. | Journal of clinical anesthesia 20100501 |
| Population pharmacokinetics of dexmedetomidine in infants after open heart surgery. | Anesthesia and analgesia 20100501 |
| Effects of fentanyl-lidocaine-propofol and dexmedetomidine-lidocaine-propofol on tracheal intubation without use of muscle relaxants. | The Kaohsiung journal of medical sciences 20100501 |
| [A combination of dexmedetomidine with ketamine and opioids results in significant inhibition of hemodynamic changes associated with laparoscopic cholecystectomy and in prolongation of postoperative analgesia]. | Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti 20100501 |
| The effectiveness of dexmedetomidine in experimental spinal cord injury compared to methylprednisolone in rats. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100401 |
| Hemodynamics and bispectral index (BIS) of dogs anesthetized with midazolam and ketamine associated with medetomidine or dexmedetomidine and submitted to ovariohysterectomy. | Acta cirurgica brasileira 20100401 |
| Propofol/dexmedetomidine and propofol/ketamine combinations for anesthesia in pediatric patients undergoing transcatheter atrial septal defect closure: a prospective randomized study. | Clinical therapeutics 20100401 |
| Anesthetic management of a pituitary tumor resection with dexmedetomidine. | AANA journal 20100401 |
| The alpha(2)-adrenoceptor agonist dexmedetomidine suppresses memory formation only at doses attenuating the perception of sensory input. | European journal of pharmacology 20100310 |
| Overview of total intravenous anesthesia in children. | Paediatric anaesthesia 20100301 |
| Neuroprotective effects of a combination of dexmedetomidine and hypothermia after incomplete cerebral ischemia in rats. | Acta anaesthesiologica Scandinavica 20100301 |
| Addition of dexmedetomidine to bupivacaine for greater palatine nerve block prolongs postoperative analgesia after cleft palate repair. | European journal of anaesthesiology 20100301 |
| Intraoperative administration of dexmedetomidine reduces the analgesic requirements for children undergoing hypospadius surgery. | European journal of anaesthesiology 20100301 |
| Sedation trends in the 21st century: the transition to dexmedetomidine for radiological imaging studies. | Paediatric anaesthesia 20100301 |
| Dexmedetomidine: perioperative applications in children. | Paediatric anaesthesia 20100301 |
| Pretreatment with dexmedetomidine or thiopental decreases myoclonus after etomidate: a randomized, double-blind controlled trial. | The Journal of surgical research 20100301 |
| A comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during fibreoptic nasotracheal intubation. | Anaesthesia 20100301 |
| [Incidence and duration of postoperative delirium after cardiac surgery : Comparison between dexmedetomidine and morphine for postoperative sedation and analgesia]. | Der Anaesthesist 20100301 |
| [Effect of the initial loading dose of dexmedetomidine on hemodynamics in pediatric patients undergoing cardiac surgery]. | Masui. The Japanese journal of anesthesiology 20100301 |
| Cardiopulmonary and isoflurane-sparing effects of epidural or intravenous infusion of dexmedetomidine in cats undergoing surgery with epidural lidocaine. | Veterinary anaesthesia and analgesia 20100301 |
| Combination of dexmedetomidine with buprenorphine enhances the antinociceptive effect to a thermal stimulus in the cat compared with either agent alone. | Veterinary anaesthesia and analgesia 20100301 |
| Dexmedetomidine and magnesium sulfate in the perioperative management of a child undergoing laparoscopic resection of bilateral pheochromocytomas. | Journal of clinical anesthesia 20100301 |
| Dexmedetomidine infusion during surgery in patients with a pheochromocytoma. | Acta anaesthesiologica Scandinavica 20100301 |
| The effect of dexmedetomidine on liver histopathology in a rat sepsis model: an experimental pilot study. | Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20100301 |
| Effects of variation in the human alpha2A- and alpha2C-adrenoceptor genes on cognitive tasks and pain perception. | European journal of pain (London, England) 20100201 |
| A cost-minimization analysis of dexmedetomidine compared with midazolam for long-term sedation in the intensive care unit. | Critical care medicine 20100201 |
| Use of dexmedetomidine for primary sedation in a general intensive care unit. | Critical care nurse 20100201 |
| Airway catastrophes. | Current opinion in anaesthesiology 20100201 |
| A comparison of propofol and dexmedetomidine for intravenous sedation: a randomized, crossover study of the effects on the central and autonomic nervous systems. | Anesthesia and analgesia 20100201 |
| Dexmedetomidine for procedural sedation in the emergency department. | European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20100201 |
| Desensitization of vascular response in vivo: contribution of genetic variation in the [alpha]2B-adrenergic receptor subtype. | Journal of hypertension 20100201 |
| Assessing the comparative value of sedatives in the intensive care unit. | Critical care medicine 20100201 |
| Characterization of the postconditioning effect of dexmedetomidine in mouse organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation. | Anesthesiology 20100201 |
| Prolonged recovery associated with dexmedetomidine when used as a sole sedative agent in office-based oral and maxillofacial surgery procedures. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20100201 |
| Buccal administration of dexmedetomidine as a preanesthetic in children. | Journal of anesthesia 20100201 |
| Dexmedetomidine is an excellent agent for sedation status-post lung transplant. | Journal of clinical anesthesia 20100201 |
| A comparative study of dexmedetomidine with midazolam and midazolam alone for sedation during elective awake fiberoptic intubation. | Journal of clinical anesthesia 20100201 |
| Bradycardia leading to asystole during dexmedetomidine infusion in an 18 year-old double-lung transplant recipient. | Journal of clinical anesthesia 20100201 |
| Use of dexmedetomidine as the main anesthetic agent in patients with laryngo-tracheomalacia--a case report. | Middle East journal of anaesthesiology 20100201 |
| The effectiveness of dexmedetomidine infusion for sedating oral cancer patients undergoing awake fibreoptic nasal intubation. | European journal of anaesthesiology 20100101 |
| Dexmedetomidine sedation in children after cardiac surgery. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20100101 |
| Monitored anesthesia care with dexmedetomidine: a prospective, randomized, double-blind, multicenter trial. | Anesthesia and analgesia 20100101 |
| Peri-operative use of dexmedetomidine in airway reconstruction surgery for obstructive sleep apnoea. | The Journal of laryngology and otology 20100101 |
| New insights about an old foe. | Anesthesiology 20100101 |
| Effects of dexmedetomidine and propofol on lower esophageal sphincter and gastroesophageal pressure gradient in healthy volunteers. | Anesthesiology 20100101 |
| Intravenous dexmedetomidine, but not midazolam, prolongs bupivacaine spinal anesthesia. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20100101 |
| Withdrawal from multiple sedative agent therapy in an infant: is dexmedetomidine the cause or the cure? | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20100101 |
| Dexmedetomidine and pediatric (cardiac) critical care--are we there yet? | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20100101 |
| Dexmedetomidine: are tolerance and withdrawal going to be an issue with long-term infusions? | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20100101 |
| Dexmedetomidine as an adjunct to anesthetic induction to attenuate hemodynamic response to endotracheal intubation in patients undergoing fast-track CABG. | Annals of cardiac anaesthesia 20100101 |
| Dexmedetomidine in the neurointensive care unit. | Discovery medicine 20100101 |
| Novel use of intraoperative dexmedetomidine infusion for sedation during spinal cord stimulator lead placement via surgical laminectomy. | Pain physician 20100101 |
| Effect of dexmedetomidine on testicular torsion/detorsion damage in rats. | Urologia internationalis 20100101 |
| [Effect of dexmedetomidine on bispectral index and auditory evoked potential index during anesthesia with target controlled infusion of propofol and remifentanyl]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20100101 |
| The effect of dexmedetomidine on agitation during weaning of mechanical ventilation in critically ill patients. | Anaesthesia and intensive care 20100101 |
| Optimizing sustained use of sedation in mechanically ventilated patients: focus on safety. | Current drug safety 20100101 |
| Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial. | Critical care (London, England) 20100101 |
| Evaluation of the hypnotic and hemodynamic effects of dexmedetomidine on propofol-sedated swine. | Experimental animals 20100101 |
| A Phase IIIb, randomized, double-blind, placebo-controlled, multicenter study evaluating the safety and efficacy of dexmedetomidine for sedation during awake fiberoptic intubation. | American journal of therapeutics 20100101 |
| The complex interplay between delirium, sepsis and sedation. | Critical care (London, England) 20100101 |
| The use of sub-anesthetic intravenous ketamine and adjuvant dexmedetomidine when treating acute pain from CRPS. | Pain physician 20100101 |
| Hemodynamic effects of the combination of dexmedetomidine-fentanyl versus midazolam-fentanyl in children undergoing cardiac surgery with cardiopulmonary bypass. | Revista brasileira de anestesiologia 20100101 |
| Alpha-2 adrenoceptor agonists and sepsis: improved survival? | Critical care (London, England) 20100101 |
| Perineural dexmedetomidine provides an increased duration of analgesia to a thermal stimulus when compared with a systemic control in a rat sciatic nerve block. | Regional anesthesia and pain medicine 20100101 |
| A comparison of intravenous sedation with two doses of dexmedetomidine: 0.2 µg/kg/hr Versus 0.4 µg/kg/hr. | Anesthesia progress 20100101 |
| Analysis of heart rate variability dynamics during propofol and dexmedetomidine anesthesia. | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20100101 |
| Determination of dexmedetomidine in human plasma using high performance liquid chromatography coupled with tandem mass spectrometric detection: application to a pharmacokinetic study. | Journal of pharmaceutical and biomedical analysis 20091205 |
| Comparison between dexmedetomidine and midazolam for sedation of eclampsia patients in the intensive care unit. | Journal of critical care 20091201 |
| ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors. | Neurochemistry international 20091201 |
| Re: The neuroprotective effect of dexmedetomidine in the hippocampus of rabbits after subarachnoid hemorrhage (Cosar et al. Surg Neurol 2009;71:54-59). | Surgical neurology 20091201 |
| A new dosing protocol reduces dexmedetomidine-associated hypotension in critically ill surgical patients. | Journal of critical care 20091201 |
| Pharmacological profile of intrathecal fadolmidine, a alpha2-adrenoceptor agonist, in rodent models. | Naunyn-Schmiedeberg's archives of pharmacology 20091201 |
| The correlation between bispectral index and observational sedation scale in volunteers sedated with dexmedetomidine and propofol. | Anesthesia and analgesia 20091201 |
| Effects of propofol and dexmedetomidine on indocyanine green elimination assessed with LIMON to patients with early septic shock: a pilot study. | Journal of critical care 20091201 |
| An updated focused review of dexmedetomidine in adults. | The Annals of pharmacotherapy 20091201 |
| A balanced anesthesia with dexmedetomidine decreases postoperative nausea and vomiting after laparoscopic surgery. | Saudi medical journal 20091201 |
| Impact of dexmedetomidine on analgesic requirements in patients after cardiac surgery in a fast-track recovery room setting. | Pharmacotherapy 20091201 |
| Dexmedetomidine-associated bradycardia progressing to pulseless electrical activity: case report and review of the literature. | Pharmacotherapy 20091201 |
| Awake laminotomy and discectomy using Dexmedetomidine as anesthetic. | Puerto Rico health sciences journal 20091201 |
| Effects of dexmedetomidine sedation on the EEG in children. | Paediatric anaesthesia 20091201 |
| [Effect of dexmedetomidine on anesthetic requirements in cardiovascular surgery]. | Masui. The Japanese journal of anesthesiology 20091201 |
| [Apnea and severe respiratory depression induced by dexmedetomidine after general anesthesia in intensive care unit]. | Masui. The Japanese journal of anesthesiology 20091201 |
| Dexmedetomidine use in a pediatric cardiac intensive care unit: can we use it in infants after cardiac surgery? | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20091101 |
| Dexmedetomidine pharmacokinetics in pediatric intensive care--a pooled analysis. | Paediatric anaesthesia 20091101 |
| 'Above all, do no harm': hippocrates. | Anesthesiology 20091101 |
| Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study). | Anesthesiology 20091101 |
| Comparison between dexmedetomidine and remifentanil for intraoperative controlled hypotension. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20091101 |
| Perineural dexmedetomidine added to ropivacaine causes a dose-dependent increase in the duration of thermal antinociception in sciatic nerve block in rat. | Anesthesiology 20091101 |
| Dexmedetomidine as sole sedative during percutaneous carotid artery stenting in a patient with severe chronic obstructive pulmonary disease. | Minerva anestesiologica 20091101 |
| Traumatic brain injury: neuroprotective anaesthetic techniques, an update. | Injury 20091101 |
| [Perioperative management of a patient with myasthenia gravis using dexmedetomidine]. | Masui. The Japanese journal of anesthesiology 20091101 |
| Profound reduction in sedation and analgesic requirements using extended dexmedetomidine infusions in a patient with an open abdomen. | Military medicine 20091101 |
| Comparison of patient-controlled analgesia with and without dexmedetomidine following spine surgery in children. | Journal of clinical anesthesia 20091101 |
| Alpha-2 adrenergic agonists for the prevention of cardiac complications among patients undergoing surgery. | The Cochrane database of systematic reviews 20091007 |
| Benzodiazepines for delirium. | The Cochrane database of systematic reviews 20091007 |
| Evaluation of cardiorespiratory effects of combinations of dexmedetomidine and atropine in cats. | Journal of feline medicine and surgery 20091001 |
| The combined neuroprotective effects of lidocaine and dexmedetomidine after transient forebrain ischemia in rats. | Acta anaesthesiologica Scandinavica 20091001 |
| The effect of dexmedetomidine sedation on brachial plexus block in patients with end-stage renal disease. | European journal of anaesthesiology 20091001 |
| Thermal antinociception after dexmedetomidine administration in cats: a comparison between intramuscular and oral transmucosal administration. | Journal of feline medicine and surgery 20091001 |
| Sedation and regional anesthesia. | Current opinion in anaesthesiology 20091001 |
| Dexmedetomidine-ketamine combination mitigates acute lung injury in haemorrhagic shock rats. | Resuscitation 20091001 |
| Cardiovascular reflex responses to temporal reduction in arterial pressure during dexmedetomidine infusion: a double-blind, randomized, and placebo-controlled study. | British journal of anaesthesia 20091001 |
| Dexmedetomidine for awake fiberoptic intubation in a parturient with spinal muscular atrophy type III for cesarean delivery. | International journal of obstetric anesthesia 20091001 |
| Re: Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children. | British journal of anaesthesia 20091001 |
| Successful use of dexmedetomidine for sedation in a 24-week gestational age neonate. | The Annals of pharmacotherapy 20091001 |
| Prolonged dexmedetomidine infusions in critically ill infants and children. | Indian pediatrics 20090901 |
| Effects of dexmedetomidine or methylprednisolone on inflammatory responses in spinal cord injury. | Acta anaesthesiologica Scandinavica 20090901 |
| Dexmedetomidine and proprofol in complex microlaryngeal surgery in infants. | International journal of pediatric otorhinolaryngology 20090901 |
| Evaluation of the muscular relaxant effect of dexmedetomidine or medetomidine in cats. | Veterinary research communications 20090901 |
| Perioperative use of dexmedetomidine in an infant with familial dysautonomia. | British journal of anaesthesia 20090901 |
| Dexmedetomidine chemical restraint of two raptor species undergoing inhalation anaesthesia. | Veterinary research communications 20090901 |
| Alpha2-receptor agonists for treatment and prevention of iatrogenic opioid abstinence syndrome in critically ill patients. | The Annals of pharmacotherapy 20090901 |
| A comparison of dexmedetomidine with propofol for magnetic resonance imaging sleep studies in children. | Anesthesia and analgesia 20090901 |
| Sedation and drugs in pediatric patients: what is new? | Paediatric anaesthesia 20090901 |
| New caudal additives in children: benefit vs. risk? | Acta anaesthesiologica Scandinavica 20090901 |
| Update on dexmedetomidine for adult ICU sedation. | Connecticut medicine 20090901 |
| Sedation challenges in the pediatric ICU: is dexmedetomidine the solution? | Indian pediatrics 20090901 |
| Results of a pilot study on the effects of propofol and dexmedetomidine on inflammatory responses and intraabdominal pressure in severe sepsis. | Journal of clinical anesthesia 20090901 |
| Dexmedetomidine/ketamine for diagnostic cardiac catheterization in a child with idiopathic pulmonary hypertension. | Journal of clinical anesthesia 20090901 |
| Dexmedetomidine supplemented with local anesthesia for awake laryngoplasty. | Journal of clinical anesthesia 20090901 |
| The influences of propofol and dexmedetomidine on circadian gene expression in rat brain. | Brain research bulletin 20090814 |
| Risk and safety of pediatric sedation/anesthesia for procedures outside the operating room. | Current opinion in anaesthesiology 20090801 |
| Addition of clonidine or dexmedetomidine to bupivacaine prolongs caudal analgesia in children. | British journal of anaesthesia 20090801 |
| Dexmedetomidine, an alpha2-adrenergic agonist, inhibits neuronal delayed-rectifier potassium current and sodium current. | British journal of anaesthesia 20090801 |
| Dexmedetomidine for procedural sedation in children with autism and other behavior disorders. | Pediatric neurology 20090801 |
| The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors. | Anesthesia and analgesia 20090801 |
| Using a thoracic epidural catheter in a high-risk pediatric transplant patient. | The Annals of thoracic surgery 20090801 |
| [Effect of dexmedetomidine on intraoperative somatosensory evoked potential monitoring]. | Masui. The Japanese journal of anesthesiology 20090801 |
| [Cardiac arrest induced by dexmedetomidine]. | Masui. The Japanese journal of anesthesiology 20090801 |
| [Anesthetic management in a case of myotonic distrophy with dexmedetomidine]. | Masui. The Japanese journal of anesthesiology 20090801 |
| Dexmedetomidine use in general anaesthesia. | Current drug targets 20090801 |
| New drugs for epidural analgesia. | Current drug targets 20090801 |
| Cesarean section and primary pulmonary hypertension: the role of intravenous dexmedetomidine. | International journal of obstetric anesthesia 20090701 |
| Intravenous dexmedetomidine as an adjunct for labor analgesia and cesarean delivery anesthesia in a parturient with a tethered spinal cord. | International journal of obstetric anesthesia 20090701 |
| Intravenous dexmedetomidine for obstetric anaesthesia and analgesia: converting a challenge into an opportunity? | International journal of obstetric anesthesia 20090701 |
| Suppression of shivering during hypothermia using a novel drug combination in healthy volunteers. | Anesthesiology 20090701 |
| A comparison of the effects on respiratory carbon dioxide response, arterial blood pressure, and heart rate of dexmedetomidine, propofol, and midazolam in sevoflurane-anesthetized rabbits. | Anesthesia and analgesia 20090701 |
| Pharmacology of sedative-analgesic agents: dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists. | Critical care clinics 20090701 |
| The effects of dexmedetomidine and fentanyl on emergence characteristics after adenoidectomy in children. | Anaesthesia and intensive care 20090701 |
| Comparing dexmedetomidine with midazolam for sedation of patients in the ICU. | JAMA 20090617 |
| Comparing dexmedetomidine with midazolam for sedation of patients in the ICU. | JAMA 20090617 |
| Comparing dexmedetomidine with midazolam for sedation of patients in the ICU. | JAMA 20090617 |
| Comparing dexmedetomidine with midazolam for sedation of patients in the ICU. | JAMA 20090617 |
| Effects of dexmedetomidine on regulating endotoxin-induced up-regulation of inflammatory molecules in murine macrophages. | The Journal of surgical research 20090615 |
| Intravenous dexmedetomidine prolongs bupivacaine spinal analgesia. | Middle East journal of anaesthesiology 20090601 |
| Sedating the child with congenital heart disease. | Anesthesiology clinics 20090601 |
| Bispectral index-guided intraoperative sedation with dexmedetomidine and midazolam infusion in outpatient cataract surgery. | Minerva anestesiologica 20090501 |
| The use of dexmedetomidine in critically ill children. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20090501 |
| Dexmedetomidine attenuates isoflurane-induced neurocognitive impairment in neonatal rats. | Anesthesiology 20090501 |
| Postoperative intensive care unit drug fever caused by dexmedetomidine. | Anesthesia and analgesia 20090501 |
| Influence of anesthetic management on quality of magnetoencephalography scan data in pediatric patients: a case series. | Paediatric anaesthesia 20090501 |
| Dexmedetomidine suppresses the decrease in blood pressure during anesthetic induction and blunts the cardiovascular response to tracheal intubation. | Journal of clinical anesthesia 20090501 |
| Dexmedetomidine for deep brain stimulator placement in a child with primary generalized dystonia: case report and literature review. | Journal of clinical anesthesia 20090501 |
| Dexmedetomidine blunts haemodynamic and intraocular pressure responses to tracheal intubation. | European journal of anaesthesiology 20090501 |
| Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis. | World journal of gastroenterology 20090407 |
| Antihyperalgesic effect of systemic dexmedetomidine and gabapentin in a rat model of monoarthritis. | Brain research 20090406 |
| Direct effect of dexmedetomidine on rat isolated aorta involves endothelial nitric oxide synthesis and activation of the lipoxygenase pathway. | Clinical and experimental pharmacology & physiology 20090401 |
| Severe rash associated with dexmedetomidine use during mechanical ventilation. | Pharmacotherapy 20090401 |
| Alpha2-adrenergic agonists and their role in the prevention of perioperative adverse cardiac events. | AANA journal 20090401 |
| Does dexmedetomidine reduce secondary damage after spinal cord injury? An experimental study. | European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20090301 |
| Dexmedetomidine sedation for pediatric post-Fontan procedure patients. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20090301 |
| Clonidine and dexmedetomidine produce antinociceptive synergy in mouse spinal cord. | Anesthesiology 20090301 |
| An exaggerated hypertensive response to glycopyrrolate therapy for bradycardia associated with high-dose dexmedetomidine. | Anesthesia and analgesia 20090301 |
| Effect of dexmedetomidine added to spinal bupivacaine for urological procedures. | Saudi medical journal 20090301 |
| [Anesthesia induction for patients with cervical spinal disease]. | Masui. The Japanese journal of anesthesiology 20090301 |
| Effects of alpha-adrenergic agonists on pain modulation in diffuse noxious inhibitory control. | Journal of medical and dental sciences 20090301 |
| A new era for sedation in ICU patients. | JAMA 20090204 |
| Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. | JAMA 20090204 |
| Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation. | Intensive care medicine 20090201 |
| Does pethidine affect the cardiovascular and sedative effects of dexmedetomidine in dogs? | The Journal of small animal practice 20090201 |
| Effect of dexmedetomidine on the characteristics of bupivacaine in a caudal block in pediatrics. | Acta anaesthesiologica Scandinavica 20090201 |
| Dexmedetomidine anaesthesia for patients with obstructive sleep apnoea undergoing bariatric surgery. | European journal of anaesthesiology 20090201 |
| Prolonged use of dexmedetomidine in the paediatric cardiothoracic intensive care unit. | Cardiology in the young 20090201 |
| Propofol and midazolam inhibit conscious memory processes very soon after encoding: an event-related potential study of familiarity and recollection in volunteers. | Anesthesiology 20090201 |
| [Planned sedation with dexmedetomidine hydrochloride after pediatric cardiac surgery; an institutional experience]. | Kyobu geka. The Japanese journal of thoracic surgery 20090201 |
| Determination of the pharmacodynamic interaction of propofol and dexmedetomidine during esophagogastroduodenoscopy in children. | Paediatric anaesthesia 20090201 |
| Hypoglycemia associated with dexmedetomidine overdose in a child? | Journal of clinical anesthesia 20090201 |
| Expressions of genes encoding drug-metabolizing enzymes are altered after sevoflurane, isoflurane, propofol or dexmedetomidine anesthesia. | Biomedical research (Tokyo, Japan) 20090201 |
| Remifentanil-propofol vs dexmedetomidine-propofol--anesthesia for supratentorial craniotomy. | Middle East journal of anaesthesiology 20090201 |
| Benzodiazepines for delirium. | The Cochrane database of systematic reviews 20090121 |
| The neuroprotective effect of dexmedetomidine in the hippocampus of rabbits after subarachnoid hemorrhage. | Surgical neurology 20090101 |
| Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia. | British journal of anaesthesia 20090101 |
| Effects of nitric oxide synthase inhibition on dexmedetomidine-induced vasoconstriction in healthy human volunteers. | British journal of anaesthesia 20090101 |
| Propofol-sparing or lipid-sparing? | Paediatric anaesthesia 20090101 |
| Dexmedetomidine sedation (and cardiac perforation, pericardial tamponade, cardiac arrest, and cardiopulmonary resuscitation) leading to refractory cardiogenic shock. | Anesthesia and analgesia 20090101 |
| Caution is necessary when dexmedetomidine is used off-label, especially when combined with other sedatives. | Anesthesia and analgesia 20090101 |
| Dexmedetomidine and refractory cardiogenic shock. | Anesthesia and analgesia 20090101 |
| Intravenous dexmedetomidine infusion for labour analgesia in patient with preeclampsia. | European journal of anaesthesiology 20090101 |
| Addition of dexmedetomidine or lornoxicam to prilocaine in intravenous regional anaesthesia for hand or forearm surgery: a randomized controlled study. | Clinical drug investigation 20090101 |
| Dexmedetomidine as a substitute for remifentanil in ambulatory gynecologic laparoscopic surgery. | Saudi medical journal 20090101 |
| Effect of dexmedetomidine on ischemia-reperfusion injury in rat kidney: a histopathologic study. | Renal failure 20090101 |
| [Anesthetic management using epidural anesthesia and dexmedetomidine for thoracoscopic lung resection in a patient with compromised lung functions]. | Masui. The Japanese journal of anesthesiology 20090101 |
| Awake thyroidectomy under local anesthesia and dexmedetomidine infusion. | Military medicine 20090101 |
| Intra- and inter-individual variation of BIS-index and Entropy during controlled sedation with midazolam/remifentanil and dexmedetomidine/remifentanil in healthy volunteers: an interventional study. | Critical care (London, England) 20090101 |
| Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy. | Journal of anesthesia 20090101 |
| Dexmedetomidine facilitates induction of noninvasive positive pressure ventilation for acute respiratory failure in patients with severe asthma. | Journal of anesthesia 20090101 |
| Treating agitation with dexmedetomidine in the ICU. | Dimensions of critical care nursing : DCCN 20090101 |
| BIS and spectral entropy monitoring during sedation with midazolam/remifentanil and dexmedetomidine/remifentanil. | Critical care (London, England) 20090101 |
| Opioid-free balanced anesthesia for cervical ganglionectomy subsequent to recent ultra rapid opioid detoxification. | Pain medicine (Malden, Mass.) 20090101 |
| Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: a randomised open-label trial. | Critical care (London, England) 20090101 |
| Intranasal dexmedetomidine premedication is comparable with midazolam in burn children undergoing reconstructive surgery. | Journal of burn care & research : official publication of the American Burn Association 20090101 |
| Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. | Psychosomatics 20090101 |
| Tackling agitated delirium--the tip of the iceberg. | Critical care (London, England) 20090101 |
| Dexmedetomidine as a novel therapeutic for postoperative pain in a patient treated with buprenorphine. | Journal of opioid management 20090101 |
| Dexmedetomidine-induced cerebral hypoperfusion exacerbates ischemic brain injury in rats. | Journal of anesthesia 20090101 |
| Sedation improves early outcome in severely septic Sprague Dawley rats. | Critical care (London, England) 20090101 |
| Dexmedetomidine sedation for carotid endarterectomy. | Anestezjologia intensywna terapia 20090101 |
| Evaluation of the potential for interaction between a metaflumizone-amitraz combination and dexmedetomidine hydrochloride in dogs. | Veterinary therapeutics : research in applied veterinary medicine 20090101 |
| Psychosedation with dexmedetomidine hydrochloride during minor oral surgery. | Anesthesia progress 20090101 |
| Immunosedation: a consideration for sepsis. | Critical care (London, England) 20090101 |
| Effects of dexmedetomidine pretreatment on bupivacaine cardiotoxicity in rats. | Regional anesthesia and pain medicine 20090101 |
| Investigation of modulation of the alpha-2 receptor in tetrahydropalmatine (THP) analgesia in male Sprague-Dawley rats. | Journal of dietary supplements 20090101 |
| In vitro and in vivo profiling of fadolmidine, a novel potent alpha(2)-adrenoceptor agonist with local mode of action. | European journal of pharmacology 20081203 |
| Dexmedetomidine causes prolonged recovery when compared with midazolam/fentanyl combination in outpatient shock wave lithotripsy. | European journal of anaesthesiology 20081201 |
| Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphine. | British journal of pharmacology 20081201 |
| Anesthesia for outpatient cosmetic surgery. | Current opinion in anaesthesiology 20081201 |
| A comparison of dexmedetomidine-midazolam with propofol for maintenance of anesthesia in children undergoing magnetic resonance imaging. | Anesthesia and analgesia 20081201 |
| Recovery profiles from dexmedetomidine as a general anesthetic adjuvant in patients undergoing lower abdominal surgery. | Anesthesia and analgesia 20081201 |
| Effects of dexmedetomidine on propofol and remifentanil infusion rates during total intravenous anesthesia for spine surgery in adolescents. | Paediatric anaesthesia 20081201 |
| Dexmedetomidine: more than a sedative and analgesic. | Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20081201 |
| Effects of dexmedetomidine on regulating pulmonary inflammation in a rat model of ventilator-induced lung injury. | Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20081201 |
| Effects of dexmedetomidine on intraoperative motor and somatosensory evoked potential monitoring during spinal surgery in adolescents. | Paediatric anaesthesia 20081101 |
| Dexmedetomidine infusion as adjunctive therapy to benzodiazepines for acute alcohol withdrawal. | The Annals of pharmacotherapy 20081101 |
| Postoperative pain status after intraoperative systemic dexmedetomidine and epidural neostigmine in patients undergoing lower abdominal surgery. | European journal of anaesthesiology 20081101 |
| Dexmedetomidine as the primary sedative during invasive procedures in infants and toddlers with congenital heart disease. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20081101 |
| Dexmedetomidine: a novel drug for the treatment of atrial and junctional tachyarrhythmias during the perioperative period for congenital cardiac surgery: a preliminary study. | Anesthesia and analgesia 20081101 |
| Induced hypotension in orthognathic surgery: a comparative study of 2 pharmacological protocols. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20081101 |
| Advantageous effects of dexmedetomidine on haemodynamic and recovery responses during extubation for intracranial surgery. | European journal of anaesthesiology 20081001 |
| Alpha2-adrenoceptor action on cell proliferation and mammary tumour growth in mice. | British journal of pharmacology 20081001 |
| Anesthesia for functional neurosurgery: the role of dexmedetomidine. | Current opinion in anaesthesiology 20081001 |
| The effect of dexmedetomidine on perioperative hemodynamics in patients undergoing craniotomy. | Anesthesia and analgesia 20081001 |
| Anesthetic management of adenotonsillectomy in a child with bidirectional superior cavapulmonary shunt. | Paediatric anaesthesia 20081001 |
| A combination of ketamine and dexmedetomidine sedation with caudal anesthesia during incarcerated inguinal hernia repair in three high-risk infants. | Paediatric anaesthesia 20081001 |
| Dexmedetomidine and ketamine for large anterior mediastinal mass biopsy. | Paediatric anaesthesia 20081001 |
| Dexmedetomidine weakens dynamic cerebral autoregulation as assessed by transfer function analysis and the thigh cuff method. | Anesthesiology 20081001 |
| Future directions in endoscopic sedation. | Gastrointestinal endoscopy clinics of North America 20081001 |
| Dexmedetomidine: a useful adjunct to consider in some high-risk situations. | AANA journal 20081001 |
| Evaluation of analgesic and sedative effects of continuous infusion of dexmedetomidine by measuring somatosensory- and auditory-evoked potentials in the rat. | Veterinary anaesthesia and analgesia 20080901 |
| The effects of L-659,066, a peripheral alpha2-adrenoceptor antagonist, on dexmedetomidine-induced sedation and bradycardia in dogs. | Veterinary anaesthesia and analgesia 20080901 |
| Sedation during ophthalmic surgery. | European journal of anaesthesiology 20080901 |
| Effect of intra-articular dexmedetomidine on postoperative analgesia after arthroscopic knee surgery. | British journal of anaesthesia 20080901 |
| alpha2-Adrenergic agonists protect against radiocontrast-induced nephropathy in mice. | American journal of physiology. Renal physiology 20080901 |
| Motor and somatosensory evoked potentials are well maintained in patients given dexmedetomidine during spine surgery. | Anesthesiology 20080901 |
| Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat. | Anesthesiology 20080901 |
| Dexmedetomidine-based versus fentanyl-based total intravenous anesthesia for lumbar laminectomy. | Minerva anestesiologica 20080901 |
| Dexmedetomidine sedation for laryngeal framework surgery. | The Annals of otology, rhinology, and laryngology 20080901 |
| Antimicrobial effects of two anaesthetic agents: dexmedetomidine and midazolam. | Anaesthesia and intensive care 20080901 |
| The effects of preanesthetic, single-dose dexmedetomidine on induction, hemodynamic, and cardiovascular parameters. | Journal of clinical anesthesia 20080901 |
| Effectiveness of dexmedetomidine in reducing bleeding during septoplasty and tympanoplasty operations. | Journal of clinical anesthesia 20080901 |
| Dexmedetomidine and ketamine for fiberoptic intubation in a child with severe mandibular hypoplasia. | Journal of clinical anesthesia 20080901 |
| Comparison of dexmedetomidine-propofol vs. fentanyl-propofol for laryngeal mask insertion. | European journal of anaesthesiology 20080801 |
| Novel use of dexmedetomidine in a patient with pulmonary hypertension. | Paediatric anaesthesia 20080801 |
| Dexmedetomidine disposition in children: a population analysis. | Paediatric anaesthesia 20080801 |
| Intravenous dexmedetomidine decreases lung permeability induced by intracranial hypertension in rats. | Anesthesia and analgesia 20080801 |
| Dexmedetomidine: a review of clinical applications. | Current opinion in anaesthesiology 20080801 |
| Dexmedetomidine sedation in a patient with superior vena cava syndrome and extreme needle phobia. | Journal of cardiothoracic and vascular anesthesia 20080801 |
| [Dexmedetomidine for sedation during voice monitoring surgery in a patient with an episode of seizure]. | Masui. The Japanese journal of anesthesiology 20080801 |
| The effects of dexmedetomidine on human neutrophil apoptosis. | Biomedical research (Tokyo, Japan) 20080801 |
| Dexmedetomidine for sedation during electroencephalographic analysis in children with autism, pervasive developmental disorders, and seizure disorders. | Journal of clinical anesthesia 20080801 |
| Effects of subchronic versus acute in utero exposure to dexmedetomidine on foetal developments in rats. | Basic & clinical pharmacology & toxicology 20080801 |
| Dexmedetomidine and arousal affect subthalamic neurons. | Movement disorders : official journal of the Movement Disorder Society 20080715 |
| The influence of dexmedetomidine on ischemic rat hippocampus. | Brain research 20080707 |
| Severe hypertension and bradycardia after dexmedetomidine for radiology sedation in a patient with acute transverse myelitis. | Paediatric anaesthesia 20080701 |
| Alpha2 adrenoreceptor agonist regulates protein kinase C-induced heat shock protein 27 phosphorylation in C6 glioma cells. | Journal of neurochemistry 20080701 |
| Dexmedetomidine attenuates the hemodynamic and neuroendocrinal responses to skull-pin head-holder application during craniotomy. | Journal of neurosurgical anesthesiology 20080701 |
| High dose of dexmedetomidine was useful for general anesthesia and post-operative analgesia in a patient with postpolio syndrome. | Acta anaesthesiologica Scandinavica 20080701 |
| Intubation of an infant with Pierre Robin sequence under dexmedetomidine sedation using the Shikani Optical Stylet. | Acta anaesthesiologica Scandinavica 20080701 |
| Dexmedetomidine enhances the local anesthetic action of lidocaine via an alpha-2A adrenoceptor. | Anesthesia and analgesia 20080701 |
| The efficacy of dexmedetomidine in patients with noninvasive ventilation: a preliminary study. | Anesthesia and analgesia 20080701 |
| Sedative and cardiorespiratory effects of acepromazine or atropine given before dexmedetomidine in dogs. | The Veterinary record 20080628 |
| Sedation with dexmedetomidine for vocal fold injection. | The New Zealand medical journal 20080606 |
| A comparison of esmolol and dexmedetomidine for attenuation of intraocular pressure and haemodynamic responses to laryngoscopy and tracheal intubation. | European journal of anaesthesiology 20080601 |
| Cost of dexmedetomidine in MRI. | Paediatric anaesthesia 20080601 |
| Management of accidental spinal administration of extended-release epidural morphine. | Anesthesiology 20080601 |
| Expecting the unexpected. | Anesthesia and analgesia 20080601 |
| A comparison of intranasal dexmedetomidine and oral midazolam for premedication in pediatric anesthesia: a double-blinded randomized controlled trial. | Anesthesia and analgesia 20080601 |
| Dexmedetomidine infusion during laparoscopic bariatric surgery: the effect on recovery outcome variables. | Anesthesia and analgesia 20080601 |
| The effect of prolonged anesthesia with isoflurane, propofol, dexmedetomidine, or ketamine on neural cell proliferation in the adult rat. | Anesthesia and analgesia 20080601 |
| Dexmedetomidine sedation leading to refractory cardiogenic shock. | Anesthesia and analgesia 20080601 |
| [Postoperative management of carotid endarterectomy with dexmedetomidine--a comparison with propofol]. | Masui. The Japanese journal of anesthesiology 20080601 |
| [Ambulatory anesthesia for an adult patient with autism and epilepsy: sedation using oral and intravenous dexmedetomidine]. | Masui. The Japanese journal of anesthesiology 20080601 |
| Action of dexmedetomidine on the substantia gelatinosa neurons of the rat spinal cord. | The European journal of neuroscience 20080601 |
| The use of continuous positive airway pressure during an awake craniotomy in a patient with obstructive sleep apnea. | Journal of clinical anesthesia 20080601 |
| Autonomic cardiovascular control during a novel pharmacologic alternative to ganglionic blockade. | Clinical pharmacology and therapeutics 20080501 |
| The efficacy and neurotoxicity of dexmedetomidine administered via the epidural route. | European journal of anaesthesiology 20080501 |
| Dexmedetomidine and postoperative shivering in patients undergoing elective abdominal hysterectomy. | European journal of anaesthesiology 20080501 |
| Comparison between dexmedetomidine and remifentanil for controlled hypotension during tympanoplasty. | European journal of anaesthesiology 20080501 |
| Signalling pathways for transactivation by dexmedetomidine of epidermal growth factor receptors in astrocytes and its paracrine effect on neurons. | British journal of pharmacology 20080501 |
| High dose dexmedetomidine as the sole sedative for pediatric MRI. | Paediatric anaesthesia 20080501 |
| Hemodynamic effects of dexmedetomidine sedation for CT imaging studies. | Paediatric anaesthesia 20080501 |
| Pharmacokinetics of intravenous dexmedetomidine in children under 11 yr of age. | British journal of anaesthesia 20080501 |
| The central hypotensive effect induced by alpha 2-adrenergic receptor stimulation is dependent on endothelial nitric oxide synthase. | Journal of hypertension 20080501 |
| Dexmedetomidine: sedation, analgesia and beyond. | Expert opinion on drug metabolism & toxicology 20080501 |
| Sertindole: pharmacological and clinical profile and role in the treatment of schizophrenia. | Expert opinion on drug metabolism & toxicology 20080501 |
| Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients. | JAMA 20080402 |
| Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients. | JAMA 20080402 |
| Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients. | JAMA 20080402 |
| Effect of dexmedetomidine premedication on the intraocular pressure changes after succinylcholine and intubation. | British journal of anaesthesia 20080401 |
| Clinical efficacy of dexmedetomidine alone is less than propofol for conscious sedation during ERCP. | Gastrointestinal endoscopy 20080401 |
| Thermal antinociception after dexmedetomidine administration in cats: a dose-finding study. | Journal of veterinary pharmacology and therapeutics 20080401 |
| Transmucosal dexmedetomidine for computed tomography sedation. | Paediatric anaesthesia 20080401 |
| Postoperative management of cleft lip repair using dexmedetomidine in a child with bidirectional superior cavopulmonary shunt. | Paediatric anaesthesia 20080401 |
| [Use of high-dose dexmedetomidine infusion for anesthesia and sedation in a patient for microlaryngeal surgery maintained with spontaneous breathing]. | Masui. The Japanese journal of anesthesiology 20080401 |
| Dexmedetomidine constant rate infusion for 24 hours during and after propofol or isoflurane anaesthesia in dogs. | Veterinary anaesthesia and analgesia 20080301 |
| Dexmedetomidine increases hippocampal phosphorylated extracellular signal-regulated protein kinase 1 and 2 content by an alpha 2-adrenoceptor-independent mechanism: evidence for the involvement of imidazoline I1 receptors. | Anesthesiology 20080301 |
| Use of dexmedetomidine for sedation of children hospitalized in the intensive care unit. | Journal of hospital medicine 20080301 |
| Dexmedetomidine blunts acute hyperdynamic responses to electroconvulsive therapy without altering seizure duration. | Acta anaesthesiologica Scandinavica 20080201 |
| Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep. | Acta anaesthesiologica Scandinavica 20080201 |
| Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine. | Hypertension (Dallas, Tex. : 1979) 20080201 |
| Comparative effects of propofol vs dexmedetomidine on cerebrovascular carbon dioxide reactivity in patients with septic shock. | British journal of anaesthesia 20080201 |
| Feasibility of dexmedetomidine in facilitating extubation in the intensive care unit. | Journal of clinical pharmacy and therapeutics 20080201 |
| Effect of dexmedetomidine on cerebral blood flow velocity, cerebral metabolic rate, and carbon dioxide response in normal humans. | Anesthesiology 20080201 |
| Pro: dexmedetomidine should be used for infants and children undergoing cardiac surgery. | Journal of cardiothoracic and vascular anesthesia 20080201 |
| Con: dexmedetomidine should not be used for infants and children during cardiac surgery. | Journal of cardiothoracic and vascular anesthesia 20080201 |
| [Ultra fast-track anesthesia with operating room extubation in a patient undergoing OPCABG by combination of propofol-remifentanil-dexmedetomidine]. | Masui. The Japanese journal of anesthesiology 20080201 |
| Successful intraoperative spinal cord monitoring during scoliosis surgery using a total intravenous anesthetic regimen including dexmedetomidine. | Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 20080201 |
| Heart block and prolonged Q-Tc interval following muscle relaxant reversal: a case report. | AANA journal 20080201 |
| Inhibitory effects of the alpha-2 adrenergic agonists clonidine and dexmedetomidine on enhanced airway tone in ovalbumin-sensitized guinea pigs. | European journal of anaesthesiology 20080101 |
| Predominant role of peripheral catecholamines in the stress-induced modulation of CYP1A2 inducibility by benzo(alpha)pyrene. | Basic & clinical pharmacology & toxicology 20080101 |
| Dexmedetomidine and cardiac protection for non-cardiac surgery: a meta-analysis of randomised controlled trials. | Anaesthesia 20080101 |
| Acute discontinuation syndrome from dexmedetomidine after protracted use in a pediatric patient. | Paediatric anaesthesia 20080101 |
| Use of dexmedetomidine in the pediatric intensive care unit. | Pharmacotherapy 20080101 |
| Dexmedetomidine reduces long-term potentiation in mouse hippocampus. | Anesthesiology 20080101 |
| Perioperative events during deep brain stimulation: the experience at cleveland clinic. | Journal of neurosurgical anesthesiology 20080101 |
| Clinical uses of dexmedetomidine in pediatric patients. | Paediatric drugs 20080101 |
| The effects of dexmedetomidine on cardiac electrophysiology in children. | Anesthesia and analgesia 20080101 |
| A comparison of sedation with dexmedetomidine or propofol during shockwave lithotripsy: a randomized controlled trial. | Anesthesia and analgesia 20080101 |
| Dexmedetomidine in aesthetic facial surgery: improving anesthetic safety and efficacy. | Plastic and reconstructive surgery 20080101 |
| Dexmedetomidine continuous rate infusion during isoflurane anaesthesia in canine surgical patients. | Veterinary anaesthesia and analgesia 20080101 |
| Monitored anesthesia care with a combination of ketamine and dexmedetomidine during cardiac catheterization. | American journal of therapeutics 20080101 |
| [Drug therapy of opioid withdrawal]. | Vertex (Buenos Aires, Argentina) 20080101 |
| Patient comfort and surgeon satisfaction during cataract surgery using topical anesthesia with or without dexmedetomidine sedation. | European journal of ophthalmology 20080101 |
| High-dose dexmedetomidine-induced hypertension in a child with traumatic brain injury. | Neurocritical care 20080101 |
| [Synergistic effect between dexmedetomidine and 0.75% ropivacaine in epidural anesthesia]. | Revista da Associacao Medica Brasileira (1992) 20080101 |
| Dexmedetomidine use in critical care. | AACN advanced critical care 20080101 |
| Dexmedetomidine reduces the ischemia-reperfusion injury markers during upper extremity surgery with tourniquet. | The Journal of hand surgery 20080101 |
| Dose- and time-related effects of dexmedetomidine on mortality and inflammatory responses to endotoxin-induced shock in rats. | Journal of anesthesia 20080101 |
| Analgesic effect of dexmedetomidine in a patient with herpetic stomatitis after living-donor lung transplantation. | Journal of anesthesia 20080101 |
| Sedation of hypercyanotic spells in a neonate with tetralogy of Fallot using dexmedetomidine. | Jornal de pediatria 20080101 |
| Dexmedetomidine in anesthesia of children submitted to videolaparoscopic appendectomy: a double-blind, randomized and placebo-controlled study. | Revista da Associacao Medica Brasileira (1992) 20080101 |
| Intravenous sedation with low-dose dexmedetomidine: its potential for use in dentistry. | Anesthesia progress 20080101 |
| Bradycardia during dexmedetomidine and therapeutic hypothermia. | Journal of intensive care medicine 20080101 |
| Subcutaneous dexmedetomidine infusions to treat or prevent drug withdrawal in infants and children. | Journal of opioid management 20080101 |
| Preliminary experience with dexmedetomidine for monitored anesthesia care during ENT surgical procedures. | American journal of therapeutics 20080101 |
| Dexmedetomidine alters the cardiovascular response during infra-renal aortic cross-clamping in sevoflurane-anesthetized dogs. | Journal of investigative surgery : the official journal of the Academy of Surgical Research 20080101 |
| Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. | JAMA 20071212 |
| The use of dexmedetomidine during laryngoscopy, bronchoscopy, and tracheal extubation following tracheal reconstruction. | Paediatric anaesthesia 20071201 |
| The effects of centrally administered dexmedetomidine on cardiovascular and sympathetic function in conscious rats. | Anesthesia and analgesia 20071201 |
| Effects of epidural administration of dexmedetomidine on the minimum alveolar concentration of isoflurane in dogs. | American journal of veterinary research 20071201 |
| Clinical analgesic efficacy and side effects of dexmedetomidine in the early postoperative period after arthroscopic knee surgery. | Journal of clinical anesthesia 20071201 |
| Innovative uses of dexmedetomidine. | Journal of clinical anesthesia 20071201 |
| Effects of alpha2-adrenoceptor agonists on tetrodotoxin-resistant Na+ channels in rat dorsal root ganglion neurons. | European journal of anaesthesiology 20071101 |
| Analysis of the antinociceptive effect of systemic administration of tramadol and dexmedetomidine combination on rat models of acute and neuropathic pain. | Pharmacology, biochemistry, and behavior 20071101 |
| The impact of perioperative dexmedetomidine infusion on postoperative narcotic use and duration of stay after laparoscopic bariatric surgery. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20071101 |
| A comparison of dexmedetomidine and midazolam for sedation in third molar surgery. | Anaesthesia 20071101 |
| The effect of dexmedetomidine on electrocorticography in patients with temporal lobe epilepsy under sevoflurane anesthesia. | Anesthesia and analgesia 20071101 |
| Effect of dexmedetomidine on blood pressure and bleeding in maxillo-facial surgery. | European journal of anaesthesiology 20071101 |
| Dexmedetomidine-induced pulmonary alterations in sheep. | Research in veterinary science 20071001 |
| Dexmedetomidine as an analgesic for pediatric tonsillectomy and adenoidectomy. | Paediatric anaesthesia 20071001 |
| Dexmedetomidine sedation for the treatment of tetanus in the intensive care unit. | British journal of anaesthesia 20071001 |
| Autonomic dysfunction in tetanus - what lessons can be learnt with specific reference to alpha-2 agonists? | Anaesthesia 20071001 |
| Activation of a G protein-coupled inwardly rectifying K+ current and suppression of Ih contribute to dexmedetomidine-induced inhibition of rat hypothalamic paraventricular nucleus neurons. | Anesthesiology 20071001 |
| Translational research: addressing problems facing the anesthesiologist. | Anesthesia and analgesia 20071001 |
| Intravenous infusion of dexmedetomidine can prevent the degeneration of spinal ventral neurons induced by intrathecal morphine after a noninjurious interval of spinal cord ischemia in rats. | Anesthesia and analgesia 20071001 |
| Dexmedetomidine relieves pain associated with acute sickle cell crisis. | Journal of pain and symptom management 20071001 |
| Dexmedetomidine produces dual alpha2-adrenergic agonist and alpha1-adrenergic antagonist actions on human isolated internal mammary artery. | Journal of cardiothoracic and vascular anesthesia 20071001 |
| [Efficacy of dexmedetomidine for controlling delirium in intensive care unit patients]. | Masui. The Japanese journal of anesthesiology 20071001 |
| [Usability of AirWay Scope for awake tracheal intubation in a burn patient with difficult airway]. | Masui. The Japanese journal of anesthesiology 20071001 |
| Effects of dexmedetomidine in morbidly obese patients undergoing laparoscopic gastric bypass. | Middle East journal of anaesthesiology 20071001 |
| The cardioprotective effect of dexmedetomidine on global ischaemia in isolated rat hearts. | Resuscitation 20070901 |
| Dexmedetomidine for pediatric MRI sedation: a review of a series of cases. | Paediatric anaesthesia 20070901 |
| Pharmacokinetics of dexmedetomidine in postsurgical pediatric intensive care unit patients: preliminary study. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20070901 |
| Dexmedetomidine during coronary artery bypass grafting surgery: is it neuroprotective?--A preliminary study. | Acta anaesthesiologica Scandinavica 20070901 |
| Dexmedetomidine sedation during cataract surgery under regional anaesthesia. | British journal of anaesthesia 20070901 |
| Deep sedation with dexmedetomidine in a porcine model does not compromise the viability of free microvascular flap as depicted by microdialysis and tissue oxygen tension. | Anesthesia and analgesia 20070901 |
| Dexmedetomidine related cardiac arrest in a patient with permanent pacemaker; a cautionary tale. | Pacing and clinical electrophysiology : PACE 20070901 |
| Dexmedetomidine: do we know enough? | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20070901 |
| Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans. | Journal of the American College of Cardiology 20070814 |
| Characterization of spinal alpha-adrenergic modulation of nociceptive transmission and hyperalgesia throughout postnatal development in rats. | British journal of pharmacology 20070801 |
| Anesthesia in the patient for awake craniotomy. | Current opinion in anaesthesiology 20070801 |
| Current state of sedation/analgesia care in dentistry. | Current opinion in anaesthesiology 20070801 |
| Current world literature. | Current opinion in anaesthesiology 20070801 |
| Neonates have a spinal alpha receptor too, as do adults. | British journal of pharmacology 20070801 |
| A double-blind, crossover assessment of the sedative and analgesic effects of intranasal dexmedetomidine. | Anesthesia and analgesia 20070801 |
| The effect of dexmedetomidine on middle ear pressure. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20070801 |
| [Experience in postoperative sedation with dexmedetomidine for mandibular osteotomy]. | Masui. The Japanese journal of anesthesiology 20070801 |
| Dexmedetomidine as sole sedative for awake intubation in management of the critical airway. | Journal of clinical anesthesia 20070801 |
| Ageing and leg postjunctional alpha-adrenergic vasoconstrictor responsiveness in healthy men. | The Journal of physiology 20070701 |
| Ageing and vascular adrenoceptor desensitization: too little, too late? | The Journal of physiology 20070701 |
| Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenopus oocytes and muscarine-induced intracellular Ca2+ elevation in cultured rat dorsal root ganglia cells. | Naunyn-Schmiedeberg's archives of pharmacology 20070701 |
| Effects of preanesthetic administration of midazolam, clonidine, or dexmedetomidine on postoperative pain and anxiety in children. | Paediatric anaesthesia 20070701 |
| Dexmedetomidine does not reduce epileptiform discharges in adults with epilepsy. | Journal of neurosurgical anesthesiology 20070701 |
| Evaluation of the clinical efficacy and safety of intramuscular and intravenous doses of dexmedetomidine and medetomidine in dogs and their reversal with atipamezole. | The Veterinary record 20070630 |
| Effects of dexmedetomidine on the duration of anaesthesia and wakefulness in bupivacaine epidural block. | European journal of anaesthesiology 20070601 |
| Does dexmedetomidine reduce the injection pain due to propofol and rocuronium? | European journal of anaesthesiology 20070601 |
| Sensitive and specific liquid chromatography-tandem mass spectrometric method for the quantitation of dexmedetomidine in pediatric plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601 |
| Dexmedetomidine as a total intravenous anesthetic in infants. | Paediatric anaesthesia 20070601 |
| The effects of dexmedetomidine on myogenic motor evoked potentials in rabbits. | Anesthesia and analgesia 20070601 |
| [Airway management with dexmedetomidine for difficult airway]. | Masui. The Japanese journal of anesthesiology 20070601 |
| Opioid consumption in total intravenous anesthesia is reduced with dexmedetomidine: a comparative study with remifentanil in gynecologic videolaparoscopic surgery. | Journal of clinical anesthesia 20070601 |
| Hypothermia-induced bradycardia in a neonate receiving dexmedetomidine. | Journal of clinical anesthesia 20070601 |
| Dexmedetomidine: a novel anesthetic agent for middle ear surgery. | Recent patents on CNS drug discovery 20070601 |
| Effect of dexmedetomidine on bleeding during tympanoplasty or septorhinoplasty. | European journal of anaesthesiology 20070501 |
| Lack in effects of therapeutic concentrations of dexmedetomidine and clonidine on the neuromuscular blocking action of rocuronium in isolated rat diaphragms. | Anesthesia and analgesia 20070501 |
| Hemodynamic and respiratory changes following dexmedetomidine administration during general anesthesia: sevoflurane vs desflurane. | Paediatric anaesthesia 20070501 |
| [Dexmedetomidine is a useful concomitant anesthetic agent for perioperative management during tracheobronchial Dumon stent surgery]. | Masui. The Japanese journal of anesthesiology 20070501 |
| Alternative to ganglionic blockade with anticholinergic and alpha-2 receptor agents. | Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20070401 |
| Dexmedetomidine infusion as a supplement to isoflurane anaesthesia for vitreoretinal surgery. | British journal of anaesthesia 20070401 |
| Dexmedetomidine for the treatment of postanesthesia shivering in children. | Paediatric anaesthesia 20070401 |
| Effects of midazolam and dexmedetomidine on inflammatory responses and gastric intramucosal pH to sepsis, in critically ill patients. | British journal of anaesthesia 20070401 |
| Untying the Gordian knot. | Anesthesia and analgesia 20070401 |
| [Effect of dexmedetomidine on hemodynamics in pediatric patients following cardiac surgery]. | Masui. The Japanese journal of anesthesiology 20070401 |
| Intrathecal infusion therapy with dexmedetomidine-supplemented morphine in cancer pain. | Acta anaesthesiologica Scandinavica 20070301 |
| Dexmedetomidine: applications in pediatric critical care and pediatric anesthesiology. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20070301 |
| Adjunctive dexmedetomidine therapy in the intensive care unit: a retrospective assessment of impact on sedative and analgesic requirements, levels of sedation and analgesia, and ventilatory and hemodynamic parameters. | Pharmacotherapy 20070301 |
| Dexmedetomidine for conscious sedation in difficult awake fiberoptic intubation cases. | Journal of clinical anesthesia 20070301 |
| Additive interaction of intraperitoneal dexmedetomidine and topical nimesulide, celecoxib, and DFU for antinociception. | European journal of pharmacology 20070205 |
| Cardiovascular reactivity to mental stress is not affected by alpha2-adrenoreceptor activation or inhibition. | Psychopharmacology 20070201 |
| Pharmacological characterization and CNS effects of a novel highly selective alpha2C-adrenoceptor antagonist JP-1302. | British journal of pharmacology 20070201 |
| Initial experience with dexmedetomidine for diagnostic and interventional cardiac catheterization in children. | Paediatric anaesthesia 20070201 |
| Loss of transcranial electric motor evoked potentials during pediatric spine surgery with dexmedetomidine. | Anesthesiology 20070201 |
| Procedural sedation and analgesia research: state of the art. | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20070201 |
| Dexmedetomidine: an updated review. | The Annals of pharmacotherapy 20070201 |
| Autonomic activity during dexmedetomidine or fentanyl infusion with desflurane anesthesia. | Journal of clinical anesthesia 20070201 |
| Assessing the depth of dexmedetomidine-induced sedation with electroencephalogram (EEG)-based spectral entropy. | Acta anaesthesiologica Scandinavica 20070101 |
| Sedation and analgesia in the intensive care unit: evaluating the role of dexmedetomidine. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070101 |
| Dexmedetomidine sedation during awake craniotomy for seizure resection: effects on electrocorticography. | Journal of neurosurgical anesthesiology 20070101 |
| The comparison of dexmedetomidine and midazolam used for sedation of patients during upper endoscopy: A prospective, randomized study. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20070101 |
| Alpha2-adrenoceptor agonists. | Current opinion in investigational drugs (London, England : 2000) 20070101 |
| Dexmedetomidine for the treatment of paroxysmal autonomic instability with dystonia. | Neurocritical care 20070101 |
| Use of dexmedetomidine in patients with trisomy 21 after cardiac surgery. | Pediatric cardiology 20070101 |
| Renal function and histology after acute hemorrhage in rats under dexmedetomidine action. | Acta cirurgica brasileira 20070101 |
| Effects of dexmedetomidine on respiratory mechanics and control of breathing in normal rats. | Respiratory physiology & neurobiology 20061201 |
| Comparison of antimicrobial effects of dexmedetomidine and etomidate-lipuro with those of propofol and midazolam. | European journal of anaesthesiology 20061201 |
| Neuroprotective interaction produced by xenon and dexmedetomidine on in vitro and in vivo neuronal injury models. | Neuroscience letters 20061201 |
| Alpha2-adrenoceptor subtypes involved in the regulation of catecholamine release from the adrenal medulla of mice. | British journal of pharmacology 20061201 |
| Prolonged use of dexmedetomidine in an infant with respiratory failure following living donor liver transplantation. | Paediatric anaesthesia 20061201 |
| Using dexmedetomidine to manage patients with cocaine and opioid withdrawal, who are undergoing cerebral angioplasty for cerebral vasospasm. | Anesthesia and analgesia 20061201 |
| Do the right thing (or Do the market exclusivity thing?). | Anesthesiology 20061201 |
| A phase I, two-center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in children. | Anesthesiology 20061201 |
| [Effects of dexmedetomidine hydrochloride on postoperative sedation in cardiovascular surgery]. | Kyobu geka. The Japanese journal of thoracic surgery 20061201 |
| Comparison of buccal and intramuscular dexmedetomidine premedication for arthroscopic knee surgery. | Journal of clinical anesthesia 20061201 |
| Cardiopulmonary effects of dexmedetomidine in goats and sheep anaesthetised with sevoflurane. | The Veterinary record 20061104 |
| Dexmedetomidine as an anaesthetic adjuvant in patients undergoing intracranial tumour surgery: a double-blind, randomized and placebo-controlled study. | British journal of anaesthesia 20061101 |
| The effects of pre-operative dexmedetomidine infusion on hemodynamics in patients with pulmonary hypertension undergoing mitral valve replacement surgery. | Acta anaesthesiologica Scandinavica 20061101 |
| The effects of dexmedetomidine/remifentanil and midazolam/remifentanil on auditory-evoked potentials and electroencephalogram at light-to-moderate sedation levels in healthy subjects. | Anesthesia and analgesia 20061101 |
| Clinical experience with dexmedetomidine for implantation of deep brain stimulators in Parkinson's disease. | Anesthesia and analgesia 20061101 |
| Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects. | Anesthesiology 20061101 |
| General anesthesia with dexmedetomidine in a malignant hyperthermia-susceptible woman. | Acta anaesthesiologica Scandinavica 20061101 |
| Dexmedetomidine for fiberoptic intubation of a patient with severe mental retardation and atlantoaxial instability. | Acta anaesthesiologica Scandinavica 20061101 |
| Clinical efficacy and safety of dexmedetomidine and buprenorphine, butorphanol or diazepam for canine hip radiography. | The Journal of small animal practice 20061101 |
| Dexmedetomidine does not increase the incidence of intracarotid shunting in patients undergoing awake carotid endarterectomy. | Anesthesia and analgesia 20061001 |
| Hemodynamic and anesthetic advantages of dexmedetomidine, an alpha 2-agonist, for surgery in prone position. | The Tohoku journal of experimental medicine 20061001 |
| [Anesthetic management of awake coronary artery bypass grafting using dexmedetomidine--high-dose administration and pharmacokinetic simulation]. | Masui. The Japanese journal of anesthesiology 20061001 |
| [Validity of intraoperative administration of dexmedetomidine in a patient with dermatomyositis-derived respiratory failure]. | Masui. The Japanese journal of anesthesiology 20061001 |
| Perioperative uses of dexmedetomidine. | Middle East journal of anaesthesiology 20061001 |
| Dexmedetomidine versus midazolam in outpatient third molar surgery. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20060901 |
| Ketamine and N-acetylaspartylglutamate peptidase inhibitor exert analgesia in bone cancer pain. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060901 |
| Dexmedetomidine infusion is associated with enhanced renal function after thoracic surgery. | Journal of clinical anesthesia 20060901 |
| Tracheal resection in the morbidly obese patient: the role of dexmedetomidine. | Journal of clinical anesthesia 20060901 |
| A comparison of the effect on gastric emptying of propofol or dexmedetomidine in critically ill patients: preliminary study. | European journal of anaesthesiology 20060801 |
| Response entropy is more reactive than bispectral index during laparoscopic gastric banding. | Journal of clinical monitoring and computing 20060801 |
| Clonidine decreases stress response in patients undergoing carotid endarterectomy under regional anesthesia: a prospective, randomized, double-blinded, placebo-controlled study. | Anesthesia and analgesia 20060801 |
| Propofol acts at the sigma-1 receptor and inhibits pentazocine-induced c-Fos expression in the mouse posterior cingulate and retrosplenial cortices. | Acta anaesthesiologica Scandinavica 20060801 |
| Dexmedetomidine-ketamine and propofol-ketamine combinations for anesthesia in spontaneously breathing pediatric patients undergoing cardiac catheterization. | Journal of cardiothoracic and vascular anesthesia 20060801 |
| [Pharmacokinetic simulation of high-dose administration of dexmedetomidine for decubitus treatment]. | Masui. The Japanese journal of anesthesiology 20060801 |
| Opposite to alpha2-adrenergic agonists, an imidazoline I1 selective compound does not influence reflex bradycardia in rabbits. | Autonomic neuroscience : basic & clinical 20060730 |
| Evaluation of the clinical efficacy and safety of dexmedetomidine or medetomidine in cats and their reversal with atipamezole. | Veterinary anaesthesia and analgesia 20060701 |
| Pediatric research and scholarship: another Gordian knot? | Anesthesia and analgesia 20060701 |
| The use of dexmedetomidine in pediatric cardiac surgery. | Anesthesia and analgesia 20060701 |
| Dexmedetomidine for pediatric sedation for computed tomography imaging studies. | Anesthesia and analgesia 20060701 |
| A comparison of the sedative, hemodynamic, and respiratory effects of dexmedetomidine and propofol in children undergoing magnetic resonance imaging. | Anesthesia and analgesia 20060701 |
| Short duration large dose dexmedetomidine in a pediatric patient during procedural sedation. | Anesthesia and analgesia 20060701 |
| Untying the Gordian knot. | Anesthesia and analgesia 20060701 |
| Preliminary experience with dexmedetomidine in pediatric anesthesia. | Anesthesia and analgesia 20060701 |
| Intraoperative infusion of dexmedetomidine reduces perioperative analgesic requirements. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060701 |
| [Dexmedetomidine]. | Masui. The Japanese journal of anesthesiology 20060701 |
| Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery. | Paediatric anaesthesia 20060701 |
| Monitored anesthesia care with a combination of ketamine and dexmedetomidine during magnetic resonance imaging in three children with trisomy 21 and obstructive sleep apnea. | Paediatric anaesthesia 20060701 |
| Safety and efficacy of dexmedetomidine in neurosurgical patients. | Brain injury 20060701 |
| Benzo(alpha)pyrene-induced up-regulation of CYP1A2 gene expression: role of adrenoceptor-linked signaling pathways. | Life sciences 20060620 |
| Estimation of cardiac output in a pharmacological trial using a simple method based on arterial blood pressure signal waveform: a comparison with pulmonary thermodilution and echocardiographic methods. | European journal of clinical pharmacology 20060601 |
| Dexmedetomidine vs midazolam for monitored anaesthesia care during cataract surgery. | British journal of anaesthesia 20060601 |
| Dexmedetomidine or medetomidine premedication before propofol-desflurane anaesthesia in dogs. | Journal of veterinary pharmacology and therapeutics 20060601 |
| Addition of dexmedetomidine to standard sedation regimens after cardiac surgery: an outcomes analysis. | Pharmacotherapy 20060601 |
| Propofol-induced dyskinesias controlled with dexmedetomidine during deep brain stimulation surgery. | Anesthesiology 20060601 |
| The effects of esmolol and dexmedetomidine on myocardial oxygen consumption during sympathetic stimulation in dogs. | Journal of cardiothoracic and vascular anesthesia 20060601 |
| A question of semantics. | Journal of cataract and refractive surgery 20060601 |
| The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists. | The Journal of pharmacology and experimental therapeutics 20060501 |
| Perioperative use of alpha2-adrenoceptor agonists and the cardiac patient. | European journal of anaesthesiology 20060501 |
| Dexmedetomidine as rescue drug during awake craniotomy for cortical motor mapping and tumor resection. | Anesthesia and analgesia 20060501 |
| Use of dexmedetomidine to facilitate extubation in surgical intensive-care-unit patients who failed previous weaning attempts following prolonged mechanical ventilation: a pilot study. | Respiratory care 20060501 |
| The correlation between the Richmond agitation-sedation scale and bispectral index during dexmedetomidine sedation. | European journal of anaesthesiology 20060401 |
| Dexmedetomidine facilitates withdrawal of ventilatory support. | Anesthesiology 20060401 |
| Suspected malignant hyperthermia in a child with laminin alpha2 (merosin) deficiency in the absence of a triggering agent. | Paediatric anaesthesia 20060401 |
| Use of dexmedetomidine in children after cardiac and thoracic surgery. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060301 |
| Changes in the minimum alveolar concentration of isoflurane and some cardiopulmonary measurements during three continuous infusion rates of dexmedetomidine in dogs. | Veterinary anaesthesia and analgesia 20060301 |
| Dexmedetomidine for peri-operative sedation and analgesia in alcohol addiction. | Anaesthesia 20060301 |
| Use of dexmedetomidine in awake craniotomy in adolescents: report of two cases. | Paediatric anaesthesia 20060301 |
| A comparison of dexmedetomidine versus conventional therapy for sedation and hemodynamic control during carotid endarterectomy performed under regional anesthesia. | Anesthesia and analgesia 20060301 |
| Differential effects of intravenous anesthetics on ciliary motility in cultured rat tracheal epithelial cells. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060301 |
| Pediatric sedation: Still a hard long way to go. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060301 |
| The adrenergic alpha2 receptor and sexual incentive motivation in male rats. | Pharmacology, biochemistry, and behavior 20060301 |
| Dexmedetomidine and meperidine prevent postanaesthetic shivering. | European journal of anaesthesiology 20060201 |
| Dexmedetomidine-induced decreases in accumbal dopamine in the rat are partly mediated via the locus coeruleus. | Anesthesia and analgesia 20060201 |
| The effects of dexmedetomidine on perinatal excitotoxic brain injury are mediated by the alpha2A-adrenoceptor subtype. | Anesthesia and analgesia 20060201 |
| Effect of low-dose dexmedetomidine or clonidine on the characteristics of bupivacaine spinal block. | Acta anaesthesiologica Scandinavica 20060201 |
| Dexmedetomidine as a sole sedating agent with local anesthesia in a high risk patient for axillofemoral bypass graft. | AANA journal 20060201 |
| Fentanyl or dexmedetomidine combined with desflurane for bariatric surgery. | Journal of clinical anesthesia 20060201 |
| Dexmedetomidine during local anesthesia. | Journal of anesthesia 20060101 |
| [Preoperative sedation with dexmedetomidine in patients with aneurysmal subarachnoid hemorrhage]. | Masui. The Japanese journal of anesthesiology 20060101 |
| Cardiorespiratory and minimum alveolar concentration sparing effects of a continuous intravenous infusion of dexmedetomidine in halothane or isoflurane-anaesthetized rats. | Laboratory animals 20060101 |
| [Dexmedetomidine as preventive postoperative analgesia in inguinal hernioplasty]. | Gaceta medica de Mexico 20060101 |
| Sedation using dexmedetomidine in pediatric burn patients. | Journal of burn care & research : official publication of the American Burn Association 20060101 |
| Effect of dexmedetomidine on haemodynamic responses to laryngoscopy and intubation : perioperative haemodynamics and anaesthetic requirements. | Drugs in R&D 20060101 |
| Dexmedetomidine: a novel analgesic with palliative medicine potential. | Journal of pain & palliative care pharmacotherapy 20060101 |
| The effects of dexmedetomidine on spontaneous contractions of isolated gravid rat myometrium. | Advances in therapy 20060101 |
| Dexmedetomidine as an adjuvant in the treatment of alcohol withdrawal delirium: a case report. | General hospital psychiatry 20060101 |
| Effects of dexmedetomidine on cerebral circulation and systemic hemodynamics after cardiopulmonary resuscitation in dogs. | Journal of anesthesia 20060101 |
| Repeated dexmedetomidine infusions, a postoperative living-donor liver transplantation patient. | Journal of anesthesia 20060101 |
| Systemic analgesia and co-analgesia. | Acta anaesthesiologica Belgica 20060101 |
| Dexmedetomidine to treat opioid withdrawal in infants following prolonged sedation in the pediatric ICU. | Journal of opioid management 20060101 |
| Central apnoea after balanced general anaesthesia that included dexmedetomidine. | British journal of anaesthesia 20051201 |
| Does dexmedetomidine prevent emergence delirium in children after sevoflurane-based general anesthesia? | Paediatric anaesthesia 20051201 |
| Alpha(1)-adrenergic and alpha(2)-adrenergic balance in the dorsal pons and gross behavioral activity of mice in a novel environment. | Psychopharmacology 20051101 |
| Preliminary experience with oral dexmedetomidine for procedural and anesthetic premedication. | Paediatric anaesthesia 20051101 |
| Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions. | Anesthesiology 20051101 |
| Dexmedetomidine prolongs spinal anaesthesia induced by levobupivacaine 0.5% in guinea-pigs. | The Journal of pharmacy and pharmacology 20051101 |
| Dexmedetomidine selectively suppresses dominant behaviour in aggressive and sociable mice. | European journal of pharmacology 20051031 |
| Fiberoptic intubation with dexmedetomidine in two children with spinal cord impingements. | Anesthesia and analgesia 20051001 |
| A prospective, double-blind, randomized, placebo-controlled study of dexmedetomidine as an adjunct to epidural analgesia after thoracic surgery. | Journal of cardiothoracic and vascular anesthesia 20051001 |
| Dexmedetomidine as a sole sedating agent with local anesthesia in a high-risk patient for axillofemoral bypass graft: a case report. | AANA journal 20051001 |
| [Effects of dexmedetomidine on intracranial hemodynamics in severe head injured patients]. | Neurocirugia (Asturias, Spain) 20051001 |
| Single-dose dexmedetomidine attenuates airway and circulatory reflexes during extubation. | Acta anaesthesiologica Scandinavica 20050901 |
| Single-dose dexmedetomidine reduces agitation and provides smooth extubation after pediatric adenotonsillectomy. | Paediatric anaesthesia 20050901 |
| Tolerance and withdrawal issues with sedation. | Critical care nursing clinics of North America 20050901 |
| Long-term changes in the antinociceptive potency of morphine or dexmedetomidine after a single treatment. | Anesthesia and analgesia 20050901 |
| The use of dexmedetomidine to facilitate acute discontinuation of opioids after cardiac transplantation in children. | Critical care medicine 20050901 |
| Medications to provide cooperation in the critically ill pediatric patient: a rose with a thorn. | Critical care medicine 20050901 |
| [Sedation of a pediatric patient using dexmedetomidine for day-care MRI]. | Masui. The Japanese journal of anesthesiology 20050901 |
| [Postoperative management and extubation under sedation using dexmedetomidine in a patient with old myocardial infarction after carotid endarterectomy]. | Masui. The Japanese journal of anesthesiology 20050901 |
| Comparison of dexmedetomidine and midazolam sedation for cataract surgery under topical anesthesia. | Journal of cataract and refractive surgery 20050901 |
| Dexmedetomidine for awake craniotomy without laryngeal mask. | Arquivos de neuro-psiquiatria 20050901 |
| Cardiopulmonary effects of dexmedetomidine in sevoflurane-anesthetized sheep with and without nitric oxide inhalation. | American journal of veterinary research 20050901 |
| Selective alpha2-adrenergic properties of dexmedetomidine over clonidine in the human forearm. | Journal of applied physiology (Bethesda, Md. : 1985) 20050801 |
| Dexmedetomidine in the treatment of cyclic vomiting syndrome. | Paediatric anaesthesia 20050801 |
| Sole use of dexmedetomidine has limited utility for conscious sedation during outpatient colonoscopy. | Anesthesiology 20050801 |
| Dexmedetomidine facilitates the withdrawal of ventilatory support in palliative care. | Anesthesiology 20050801 |
| Dexmedetomidine--does it have a role in the perioperative setting? | Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 20050801 |
| Prolonged infusion of dexmedetomidine for sedation following tracheal resection. | Paediatric anaesthesia 20050701 |
| Prospective evaluation of dexmedetomidine for noninvasive procedural sedation in children. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20050701 |
| Dexmedetomidine for neurological surgery. | Neurosurgery 20050701 |
| Dexmedetomidine: promising drug for pediatric sedation? | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20050701 |
| Transcanal cochlear implantation under monitored anesthesia care. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20050701 |
| Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: preliminary results. | British journal of anaesthesia 20050601 |
| Variation in the alpha2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo. | Pharmacogenetics and genomics 20050601 |
| Developmental age influences the effect of epidural dexmedetomidine on inflammatory hyperalgesia in rat pups. | Anesthesiology 20050601 |
| Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia. | European journal of anaesthesiology 20050601 |
| Dexmedetomidine exerts dose-dependent age-independent antinociception but age-dependent hypnosis in Fischer rats. | Anesthesia and analgesia 20050501 |
| Case series or uncontrolled clinical study? | Anesthesiology 20050501 |
| Alpha-2B adrenoceptor polymorphism and peripheral vasoconstriction. | Pharmacogenetics and genomics 20050501 |
| The prevention of pain from injection of propofol by dexmedetomidine and comparison with lidocaine. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20050501 |
| Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog. | Veterinary anaesthesia and analgesia 20050501 |
| Dexmedetomidine does not improve patient satisfaction when compared with propofol during mechanical ventilation. | Critical care medicine 20050501 |
| 'If you cannot measure it, you cannot improve it'. | Critical care medicine 20050501 |
| The effect of pre-anaesthetic administration of intravenous dexmedetomidine on postoperative pain in patients receiving patient-controlled morphine. | European journal of anaesthesiology 20050501 |
| The in vitro effects of clonidine and dexmedetomidine on human myometrium. | International journal of obstetric anesthesia 20050401 |
| Preventing pain on injection of rocuronium: two doses of dexmedetomidine. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20050401 |
| Dexmedetomidine and awake fiberoptic intubation for possible cervical spine myelopathy: a clinical series. | Journal of neurosurgical anesthesiology 20050401 |
| Rescue sedation with dexmedetomidine for diagnostic imaging: a preliminary report. | Paediatric anaesthesia 20050301 |
| Dexmedetomidine as the primary sedative agent for brain radiation therapy in a 21-month old child. | Paediatric anaesthesia 20050301 |
| The effects of dexmedetomidine on left ventricular function during hypoxia and reoxygenation in isolated rat hearts. | Anesthesia and analgesia 20050301 |
| Dexmedetomidine decreases the convulsive potency of bupivacaine and levobupivacaine in rats: involvement of alpha2-adrenoceptor for controlling convulsions. | Anesthesia and analgesia 20050301 |
| Effect of alpha2B-adrenoceptor polymorphism on peripheral vasoconstriction in healthy volunteers. | Anesthesiology 20050301 |
| Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice. | British journal of pharmacology 20050301 |
| Dexmedetomidine in awake craniotomy: a technical note. | Surgical neurology 20050201 |
| Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20050201 |
| Effects of exercise-induced stress and dexamethasone on plasma hormone and glucose concentrations and sedation in dogs treated with dexmedetomidine. | American journal of veterinary research 20050201 |
| Synergy between intrathecal omega-conotoxin CVID and dexmedetomidine to attenuate mechanical hypersensitivity in the rat. | European journal of pharmacology 20050104 |
| Cardiopulmonary effects and pharmacokinetics of i.v. dexmedetomidine in ponies. | Equine veterinary journal 20050101 |
| Dexmedetomidine in the treatment of withdrawal syndromes in cardiothoracic surgery patients. | Journal of intensive care medicine 20050101 |
| Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response. | Pharmacogenetics and genomics 20050101 |
| Narcotic-based sedation regimens for critically ill mechanically ventilated patients. | Critical care (London, England) 20050101 |
| Dexmedetomidine sedation in a pediatric cardiac patient scheduled for MRI. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20050101 |
| Dexmedetomidine is a useful adjunct for awake intubation. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20050101 |
| Use of dexmedetomidine in a pediatric heart transplant patient. | Pediatric cardiology 20050101 |
| Effect of subhypnotic doses of dexmedetomidine on antitumor immunity in mice. | Immunopharmacology and immunotoxicology 20050101 |
| Dexmedetomidine infusion for more than 24 hours in critically ill patients: sedative and cardiovascular effects. | Intensive care medicine 20041201 |
| Dexmedetomidine for resection of a large phaeochromocytoma with invasion into the inferior vena cava. | British journal of anaesthesia 20041201 |
| Cardiac arrest, a preventable yet a possible risk of dexmedetomidine: fact or fiction? | Anesthesiology 20041201 |
| Dexmedetomidine and asystole. | Anesthesiology 20041201 |
| Central dexmedetomidine attenuates cardiac dysfunction in a rodent model of intracranial hypertension. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20041201 |
| Dexmedetomidine infusion without loading dose in surgical patients requiring mechanical ventilation: haemodynamic effects and efficacy. | Anaesthesia and intensive care 20041201 |
| Sedation for paediatric stereotactic radiosurgery: the dexmedetomidine experience. | Anaesthesia and intensive care 20041201 |
| Comparison of the effects of dexmedetomidine and esmolol on myocardial oxygen consumption in dogs. | European journal of anaesthesiology 20041201 |
| Supraclinical concentrations of dexmedetomidine evoke norepinephrine release from rat cerebrocortical slices possible involvement of the orexin-1 receptor. | Neuroscience letters 20041130 |
| Altered glucose homeostasis in alpha2A-adrenoceptor knockout mice. | European journal of pharmacology 20041128 |
| Dexmedetomidine and opioid interactions: defining the role of dexmedetomidine for intensive care unit sedation. | Anesthesiology 20041101 |
| Dexmedetomidine pharmacodynamics: part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers. | Anesthesiology 20041101 |
| Dexmedetomidine pharmacodynamics: Part II: Crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteers. | Anesthesiology 20041101 |
| Dexmedetomidine produces its neuroprotective effect via the alpha 2A-adrenoceptor subtype. | European journal of pharmacology 20041011 |
| In vivo regulation of dopamine and noradrenaline release by alpha2A-adrenoceptors in the mouse nucleus accumbens. | Journal of neurochemistry 20041001 |
| Information loss over time defines the memory defect of propofol: a comparative response with thiopental and dexmedetomidine. | Anesthesiology 20041001 |
| Dexmedetomidine as primary sedative in CEA patients. | Journal of neurosurgical anesthesiology 20041001 |
| Enhanced visual memory effect for negative versus positive emotional content is potentiated at sub-anaesthetic concentrations of thiopental. | British journal of anaesthesia 20040901 |
| Dexmedetomidine: another arrow for the clinician's quiver. | Anesthesiology 20040901 |
| Comparative analgesic and mental effects of increasing plasma concentrations of dexmedetomidine and alfentanil in humans. | Anesthesiology 20040901 |
| Dexmedetomidine as a total intravenous anesthetic agent. | Anesthesiology 20040901 |
| [Dexmedetomidine hydrochloride (Precedex), a new sedative in intensive care, its pharmacological characteristics and clinical study result]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040901 |
| Ligand-induced alpha2-adrenoceptor endocytosis: relationship to Gi protein activation. | Biochemical and biophysical research communications 20040813 |
| Alpha2A-adrenoceptors are important modulators of the effects of D-amphetamine on startle reactivity and brain monoamines. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040701 |
| Dexmedetomidine in pediatrics: controlled studies needed. | Paediatric anaesthesia 20040601 |
| The use of dexmedetomidine to facilitate opioid and benzodiazepine detoxification in an infant. | Anesthesia and analgesia 20040601 |
| Dexmedetomidine in pediatrics: controlled studies needed. | Anesthesia and analgesia 20040601 |
| Effects of dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in rats. | Critical care medicine 20040601 |
| Difficult extubation: calming the sympathetic storm. | Anaesthesia and intensive care 20040601 |
| Comparison of medetomidine-ketamine and dexmedetomidine-ketamine anesthesia in golden-headed lion tamarins. | The Canadian veterinary journal = La revue veterinaire canadienne 20040601 |
| Dexmedetomidine overdose in the perioperative setting. | The Annals of pharmacotherapy 20040501 |
| Attentional effects of noradrenaline vary with arousal level: selective activation of thalamic pulvinar in humans. | NeuroImage 20040501 |
| Sedation during mechanical ventilation in infants and children: dexmedetomidine versus midazolam. | Southern medical journal 20040501 |
| Cardiovascular and parasympathetic effects of dexmedetomidine in healthy subjects. | Canadian journal of physiology and pharmacology 20040501 |
| Dexmedetomidine for awake carotid endarterectomy: efficacy, hemodynamic profile, and side effects. | Journal of neurosurgical anesthesiology 20040401 |
| Assessment of dexmedetomidine/ketamine anesthesia in golden-headed lion tamarins (Leontopithecus chrysomelas). | Veterinary anaesthesia and analgesia 20040401 |
| Dexmedetomidine in combination with morphine PCA provides superior analgesia for shockwave lithotripsy. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20040401 |
| Dexmedetomidine enhances analgesic action of nitrous oxide: mechanisms of action. | Anesthesiology 20040401 |
| Adding dexmedetomidine to lidocaine for intravenous regional anesthesia. | Anesthesia and analgesia 20040301 |
| Dexmedetomidine and cardiac arrest. | Anesthesiology 20040301 |
| Dexmedetomidine infusion for sedation during fiberoptic intubation: a report of three cases. | Journal of clinical anesthesia 20040301 |
| [Clonidine and anesthesia]. | La Tunisie medicale 20040301 |
| Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040201 |
| Effects of the alpha2-adrenoceptor agonist dexmedetomidine on bronchoconstriction in dogs. | Anesthesiology 20040201 |
| Hypothermia attenuates the vasodilator effects of dexmedetomidine on pial vessels in rabbits in vivo. | Anesthesia and analgesia 20040201 |
| Stress-mediated modulation of B(alpha)P-induced hepatic CYP1A1: role of catecholamines. | Chemico-biological interactions 20040115 |
| Alpha2-adrenergic receptor-induced vascular constriction in blacks and whites. | Hypertension (Dallas, Tex. : 1979) 20040101 |
| Dexmedetomidine and neurocognitive testing in awake craniotomy. | Journal of neurosurgical anesthesiology 20040101 |
| Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children. | Anesthesia and analgesia 20040101 |
| The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. | Anesthesia and analgesia 20040101 |
| Comparing dexmedetomidine prescribing patterns and safety in the naturalistic setting versus published data. | The Annals of pharmacotherapy 20040101 |
| Simultaneous quantitation of dexmedetomidine and glucuronide metabolites (G-Dex-1 and G-Dex-2) in human plasma utilizing liquid chromatography with tandem mass spectrometric detection. | Rapid communications in mass spectrometry : RCM 20040101 |
| Addition of dexmedetomidine prolongs duration of vasodilation induced by sympathetic block with mepivacaine in dogs. | Regional anesthesia and pain medicine 20040101 |
| A new method using flow cytometry to measure the effects of drugs on gastric emptying and gastrointestinal transit in mice. | Arzneimittel-Forschung 20040101 |
| Bioavailability of dexmedetomidine after extravascular doses in healthy subjects. | British journal of clinical pharmacology 20031201 |
| Clinical use of dexmedetomidine as premedicant in cats undergoing propofol-sevoflurane anaesthesia. | Journal of feline medicine and surgery 20031001 |
| ICU sedation after coronary artery bypass graft surgery: dexmedetomidine-based versus propofol-based sedation regimens. | Journal of cardiothoracic and vascular anesthesia 20031001 |
| Additional experience with dexmedetomidine in pediatric patients. | Southern medical journal 20030901 |
| Constitutive precoupling to G(i) and increased agonist potency in the alpha(2B)-adrenoceptor. | Biochemical and biophysical research communications 20030711 |
| Systemically administered alpha2-agonist-induced peripheral vasoconstriction in humans. | Anesthesiology 20030701 |
| Measurement of the low-frequency component of blood pressure variability can assist the interpretation of heart rate variability data. | Anesthesiology 20030701 |
| Awake craniotomy with dexmedetomidine in pediatric patients. | Journal of neurosurgical anesthesiology 20030701 |
| Different alpha(2) adrenoceptor subtypes control noradrenaline release and cell firing in the locus coeruleus of wildtype and monoamine oxidase-A knockout mice. | The European journal of neuroscience 20030701 |
| Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis. | The American journal of medicine 20030615 |
| Alpha2-adrenergic drug effects on brain monoamines, locomotion, and body temperature are largely abolished in mice lacking the alpha2A-adrenoceptor subtype. | Neuropharmacology 20030601 |
| A comparison of propofol infusion and propofol/isoflurane anaesthesia in dexmedetomidine premedicated dogs. | Journal of veterinary pharmacology and therapeutics 20030601 |
| Is attenuation of extracellular dopamine increase in the nucleus accumbens the major mechanism by which dexmedetomidine increases the cocaine seizure threshold in rats? | Anesthesiology 20030601 |
| The effects of dexmedetomidine and halothane on Fos expression in the spinal dorsal horn using a rat postoperative pain model. | Neuroscience letters 20030529 |
| Dexmedetomidine and meperidine additively reduce the shivering threshold in humans. | Stroke 20030501 |
| Agonist-dependent trafficking of alpha2-adrenoceptor subtypes: dependence on receptor subtype and employed agonist. | European journal of cell biology 20030501 |
| Endogenous opioids support the spinal inhibitory action of an alpha 2-adrenoceptor agonist in the decerebrated, spinalised rabbit. | Neuroscience letters 20030410 |
| Prolonged dexmedetomidine infusion as an adjunct in treating sedation-induced withdrawal. | Anesthesia and analgesia 20030401 |
| Preservation of the cortical somatosensory-evoked potential during dexmedetomidine infusion in rats. | Anesthesia and analgesia 20030401 |
| Development of bradycardia during sedation with dexmedetomidine in an infant concurrently receiving digoxin. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20030401 |
| Dexmedetomidine decreases perioperative myocardial lactate release in dogs. | Anesthesia and analgesia 20030301 |
| Effects of intrathecally administered dexmedetomidine, MPV-2426 and tizanidine on EMG in rats. | Acta anaesthesiologica Scandinavica 20030301 |
| The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats. | Anesthesia and analgesia 20030201 |
| The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. | Anesthesiology 20030201 |
| Dexmedetomidine to facilitate drug withdrawal. | Anesthesiology 20030201 |
| A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit. | Intensive care medicine 20030201 |
| Dexmedetomidine fails to cause hyperalgesia after cessation of chronic administration. | Anesthesia and analgesia 20030101 |
| Evaluation of the sedative and cardiorespiratory effects of dexmedetomidine, dexmedetomidine-butorphanol, and dexmedetomidine-ketamine in cats. | Journal of the American Veterinary Medical Association 20030101 |
| Cardiovascular reflex responses after intrathecal omega-conotoxins or dexmedetomidine in the rabbit. | Clinical and experimental pharmacology & physiology 20030101 |
| Dexmedetomidine and low-dose ketamine provide adequate sedation for awake fibreoptic intubation. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20030101 |
| Preliminary experience with dexmedetomidine in the treatment of cyclic vomiting syndrome. | American journal of therapeutics 20030101 |
| The role of the alpha2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit. | Journal of intensive care medicine 20030101 |
| Clonidine and dexmedetomidine potently inhibit peristalsis in the Guinea pig ileum in vitro. | Anesthesiology 20021201 |
| Alpha 2C-adrenoceptor mediated regulation of cortical EEG arousal. | Neuropharmacology 20021201 |
| [Next generation of drugs used in anesthesia]. | Masui. The Japanese journal of anesthesiology 20021201 |
| 24-hour Holter-monitoring in the perianaesthetic period in dogs premedicated with dexmedetomidine. | Veterinary journal (London, England : 1997) 20021101 |
| Dexmedetomidine-induced sedation in volunteers decreases regional and global cerebral blood flow. | Anesthesia and analgesia 20021001 |
| [Preliminary experience with dexmedetomidine treatment of confusional state and hyperadrenergic states at an intensive care unit]. | Revista espanola de anestesiologia y reanimacion 20021001 |
| [Dexmedetomidine, a promising drug]. | Revista espanola de anestesiologia y reanimacion 20021001 |
| New concepts in intensive care: dexmedetomidine and immunonutrition. | Middle East journal of anaesthesiology 20021001 |
| Dexmedetomidine: a novel drug for sedation and analgesia in the ICU. | Middle East journal of anaesthesiology 20021001 |
| Dexmedetomidine: a sedative-analgesic drug for the 21st century. | Middle East journal of anaesthesiology 20021001 |
| Dexmedetomidine in intensive care unit: a study of hemodynamic changes. | Middle East journal of anaesthesiology 20021001 |
| Phase III study on dexmedetomidine used for postoperative sedation of patients requiring mechanical ventilation for less than 24 hours: the French experience. | Middle East journal of anaesthesiology 20021001 |
| Autonomic nervous system responses during sedative infusions of dexmedetomidine. | Anesthesiology 20020901 |
| Dexmedetomidine increases the cocaine seizure threshold in rats. | Anesthesiology 20020901 |
| Treatment of persistent tachycardia with dexmedetomidine during off-pump cardiac surgery. | Anesthesia and analgesia 20020801 |
| The efficacy, side effects, and recovery characteristics of dexmedetomidine versus propofol when used for intraoperative sedation. | Anesthesia and analgesia 20020801 |
| Effect of synthesis parameters of the sol-gel-processed spray-dried silica gel microparticles on the release rate of dexmedetomidine. | Biomaterials 20020701 |
| The effects of dexmedetomidine on the ventilatory response to hypercapnia in rabbits. | Intensive care medicine 20020701 |
| Dexmedetomidine may impair cognitive testing during endovascular embolization of cerebral arteriovenous malformations: a retrospective case report series. | Journal of neurosurgical anesthesiology 20020701 |
| Dexmedetomidine: a new option for intractable distress in the dying. | Journal of pain and symptom management 20020701 |
| Dual alpha(2)-adrenergic agonist and alpha(1)-adrenergic antagonist actions of dexmedetomidine on human isolated endothelium-denuded gastroepiploic arteries. | Anesthesia and analgesia 20020601 |
| In vivo regulation of dopamine and noradrenaline release by alpha2A-adrenoceptors in the mouse prefrontal cortex. | The European journal of neuroscience 20020601 |
| Bispectral index-guided sedation with dexmedetomidine in intensive care: a prospective, randomized, double blind, placebo-controlled phase II study. | Critical care medicine 20020501 |
| New agents, new monitors, same unanswered questions. | Critical care medicine 20020501 |
| Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive caret. | British journal of anaesthesia 20020501 |
| Dexmedetomidine may be effective, but is it safe? | British journal of anaesthesia 20020301 |
| Effect of the alpha2-agonist dexmedetomidine on cerebral neurotransmitter concentrations during cerebral ischemia in rats. | Anesthesiology 20020201 |
| The use of alpha2-agonists during off-pump coronary artery bypass and the effects of hypothermia. | Journal of cardiothoracic and vascular anesthesia 20020201 |
| Initial experience with dexmedetomidine in paediatric-aged patients. | Paediatric anaesthesia 20020201 |
| Effects of alpha(2)-adrenoceptor agonists on perinatal excitotoxic brain injury: comparison of clonidine and dexmedetomidine. | Anesthesiology 20020101 |
| Interactions between cutaneous afferent inputs to a withdrawal reflex in the decerebrated rabbit and their control by descending and segmental systems. | Neuroscience 20020101 |
| The role of mu-opioid receptors in inflammatory hyperalgesia and alpha 2-adrenoceptor-mediated antihyperalgesia. | Neuroscience 20020101 |
| Dexmedetomidine decreases extracellular dopamine concentrations in the rat nucleus accumbens. | Brain research 20011116 |
| Spatial working memory improvement by an alpha2-adrenoceptor agonist dexmedetomidine is not mediated through alpha2C-adrenoceptor. | Progress in neuro-psychopharmacology & biological psychiatry 20011101 |
| The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairment. | Anesthesia and analgesia 20011101 |
| Dexmedetomidine: a real innovation or more of the same? | British journal of anaesthesia 20011101 |
| Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions. | British journal of anaesthesia 20011101 |
| Alkyl-substituted silica gel as a carrier in the controlled release of dexmedetomidine. | Journal of controlled release : official journal of the Controlled Release Society 20011019 |
| The synergistic antinociceptive interactions of endomorphin-1 with dexmedetomidine and/or S(+)-ketamine in rats. | Anesthesia and analgesia 20011001 |
| Clinical comparison of preanaesthetic intramuscular medetomidine and dexmedetomidine in domestic sheep. | DTW. Deutsche tierarztliche Wochenschrift 20011001 |
| Dexmedetomidine infusion and somatosensory evoked potentials. | Journal of neurosurgical anesthesiology 20011001 |
| Use of propofol and other nonbenzodiazepine sedatives in the intensive care unit. | Critical care clinics 20011001 |
| New agents for sedation in the intensive care unit. | Critical care clinics 20011001 |
| Noradrenergic modulation of serotonin release in rat dorsal and median raphé nuclei via alpha(1) and alpha(2A) adrenoceptors. | Neuropharmacology 20010901 |
| Dexmedetomidine. | Current opinion in critical care 20010801 |
| Dextromethorphan and dexmedetomidine: new agents for the control of perioperative pain. | The European journal of surgery = Acta chirurgica 20010801 |
| Comparison of medetomidine and dexmedetomidine as premedicants in dogs undergoing propofol-isoflurane anesthesia. | American journal of veterinary research 20010701 |
| Sedative but not analgesic alpha2 agonist tolerance is blocked by NMDA receptor and nitric oxide synthase inhibitors. | Anesthesiology 20010701 |
| In vitro release of dexmedetomidine from silica xerogel monoliths: effect of sol-gel synthesis parameters. | International journal of pharmaceutics 20010619 |
| The use of dexmedetomidine infusion for awake craniotomy. | Anesthesia and analgesia 20010501 |
| The effect of intravenous dexmedetomidine premedication on the dose requirement of propofol to induce loss of consciousness in patients receiving alfentanil. | Anaesthesia 20010501 |
| Dexmedetomidine, a novel alpha 2-adrenergic agonist for short-term sedation in the intensive care unit. | Connecticut medicine 20010501 |
| Comparison of medetomidine and dexmedetomidine as premedication in isoflurane anaesthesia for orthopaedic surgery in domestic sheep. | Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20010501 |
| Effects of dexmedetomidine on adrenocortical function, and the cardiovascular, endocrine and inflammatory responses in post-operative patients needing sedation in the intensive care unit. | British journal of anaesthesia 20010501 |
| Evaluation of the alpha2C-adrenoceptor as a neuropsychiatric drug target studies in transgenic mouse models. | Life sciences 20010406 |
| Effect of dexmedetomidine on the release of [3H]-noradrenaline from rat kidney cortex slices: characterization of alpha2-adrenoceptor. | Neurochemistry international 20010401 |
| Contribution of alpha(2) receptor subtypes to nerve injury-induced pain and its regulation by dexmedetomidine. | British journal of pharmacology 20010401 |
| Sedative, analgesic, and cardiovascular effects of levomedetomidine alone and in combination with dexmedetomidine in dogs. | American journal of veterinary research 20010401 |
| [Efficacy of oncologic surgery. Does anesthesia influence the postoperative outcome?]. | Zentralblatt fur Chirurgie 20010401 |
| Effect of dexmedetomidine on propofol requirements in healthy subjects. | Journal of pharmaceutical sciences 20010201 |
| Effect of dexmedetomidine, an alpha2-adrenoceptor agonist, on human pupillary reflexes during general anaesthesia. | British journal of clinical pharmacology 20010101 |
| Effects of dexmedetomidine after transient and permanent occlusion of the middle cerebral artery in the rat. | Journal of neural transmission (Vienna, Austria : 1996) 20010101 |
| Noradrenergic regulation of hippocampal place cells. | Hippocampus 20010101 |
| Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors. | British journal of pharmacology 20000401 |
| Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit. | Anaesthesia 19991201 |