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Tirofiban

CAS No.:
144494-65-5
Catalog Number:
AG001JME
Molecular Formula:
C22H36N2O5S
Molecular Weight:
440.5966
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
98+%
1 week
United States
$171
- +
Product Description
Catalog Number:
AG001JME
Chemical Name:
Tirofiban
CAS Number:
144494-65-5
Molecular Formula:
C22H36N2O5S
Molecular Weight:
440.5966
MDL Number:
MFCD05237246
IUPAC Name:
(2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid
InChI:
InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1
InChI Key:
COKMIXFXJJXBQG-NRFANRHFSA-N
SMILES:
CCCCS(=O)(=O)N[C@H](C(=O)O)Cc1ccc(cc1)OCCCCC1CCNCC1
UNII:
GGX234SI5H
Properties
Complexity:
579  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
440.234g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
440.599g/mol
Monoisotopic Mass:
440.234g/mol
Rotatable Bond Count:
14  
Topological Polar Surface Area:
113A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.4  
Literature
Title Journal
Low molecular weight dual inhibitors of factor Xa and fibrinogen binding to GPIIb/IIIa with highly overlapped pharmacophores. European journal of medicinal chemistry 20130601
Tirofiban versus abciximab: tirofiban is administered at suboptimal dosages when evaluated in an arterial thrombosis model in non-human primates. Clinical and experimental medicine 20121201
The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day. Drugs 20121112
Intra-arterial tirofiban infusion for thromboembolic complication during coil embolization of ruptured intracranial aneurysms. European journal of radiology 20121001
[Management of acute coronary syndromes in elderly patients: a single-center experience]. Giornale italiano di cardiologia (2006) 20121001
Cilostazol down-regulates the height of mural platelet thrombi formed under a high-shear rate flow in the absence of ADAMTS13 activity. European journal of pharmacology 20120915
Safety and efficacy of tirofiban in stent-assisted coil embolization of intracranial aneurysms. Neurosurgery 20120901
The impact of admission red cell distribution width on the development of poor myocardial perfusion after primary percutaneous intervention. Atherosclerosis 20120901
Severe thrombocytopenia and alveolar hemorrhage represent two types of bleeding tendency during tirofiban treatment: case report and literature review. International journal of hematology 20120901
Endovascular Treatment of Wide-necked Cerebral Aneurysms with an Acute Angle Branch Incorporated into the Sac: Novel methods of Branch Access in 8 Aneurysms. Neurointervention 20120901
Safety and efficacy of bivalirudin with glycoprotein IIb/IIIa for high-risk percutaneous coronary intervention. Indian heart journal 20120901
Two consecutive open heart operations in a small child with heparin-induced thrombocytopenia type II using anticoagulation with heparin and tirofiban. The Annals of thoracic surgery 20120801
Double interruption of antiplatelet therapy and tirofiban 'bridging' for lung cancer resection. Minerva medica 20120801
[High-dose tirofiban in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention]. Zhonghua yi xue za zhi 20120724
Early recurrent hemorrhage after coil embolization in ruptured intracranial aneurysms. Neuroradiology 20120701
Intracoronary versus intravenous high-dose bolus plus maintenance administration of tirofiban in patients undergoing primary percutaneous coronary intervention for acute ST elevation myocardial infarction. Journal of thrombosis and thrombolysis 20120701
GP IIb/IIIa inhibitors for STEMI: still the gold standard or an old survivor? Current vascular pharmacology 20120701
Intracoronary use of GP IIb/IIIa inhibitors in percutaneous coronary interventions. Current vascular pharmacology 20120701
Antibodies causing thrombocytopenia in patients treated with RGD-mimetic platelet inhibitors recognize ligand-specific conformers of αIIb/β3 integrin. Blood 20120628
Risk of bleeding after prehospital administration of high dose tirofiban for ST elevation myocardial infarction. International journal of cardiology 20120517
Acute stent thrombosis during percutaneous coronary intervention. Treatment with tirofiban. Herz 20120501
The effect of pre-hospital glycoprotein IIb-IIIa inhibitors on angiographic outcome in STEMI patients who are candidates for primary PCI. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
Drug-induced immune thrombocytopaenia: results from the Berlin Case-Control Surveillance Study. European journal of clinical pharmacology 20120501
Pharmacokinetic modeling of the high-dose bolus regimen of tirofiban in patients with severe renal impairment. Coronary artery disease 20120501
Upstream glycoprotein IIb/IIIa inhibitors for STEMI: use on-time or not at all? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
Mechanisms of Platelet Activation and Integrin αIIβ3. Korean circulation journal 20120501
Additive benefit of glycoprotein IIb/IIIa inhibition and adjunctive thrombus aspiration during primary coronary intervention: results of the Initial Thrombosuction and Tirofiban Infusion (ITTI) trial. International journal of cardiology 20120419
Fluorinated dual antithrombotic compounds based on 1,4-benzoxazine scaffold. European journal of medicinal chemistry 20120401
From snake venom toxins to therapeutics--cardiovascular examples. Toxicon : official journal of the International Society on Toxinology 20120315
Routine upstream versus selective downstream administration of glycoprotein IIb/IIIa inhibitors in patients with non-ST-elevation acute coronary syndromes: a meta-analysis of randomized trials. International journal of cardiology 20120308
Changes in BNP, hs-CRP and TIMI risk index with addition of tirofiban during primary percutaneous coronary intervention for acute STEMI: a prospective observational cohort study. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20120301
Treatment with tirofiban for acute coronary syndrome (ACS): a systematic review and network analysis. Current medical research and opinion 20120301
Net clinical benefit of prehospital glycoprotein IIb/IIIa inhibitors in patients with ST-elevation myocardial infarction and high risk of bleeding: effect of tirofiban in patients at high risk of bleeding using CRUSADE bleeding score. The Journal of invasive cardiology 20120301
Prasugrel versus tirofiban bolus with or without short post-bolus infusion with or without concomitant prasugrel administration in patients with myocardial infarction undergoing coronary stenting: the FABOLUS PRO (Facilitation through Aggrastat By drOpping or shortening Infusion Line in patients with ST-segment elevation myocardial infarction compared to or on top of PRasugrel given at loading dOse) trial. JACC. Cardiovascular interventions 20120301
The illusion of 'optimal' platelet inhibition. JACC. Cardiovascular interventions 20120301
Imaging of left main coronary artery thrombus with CT coronary angiography. Heart, lung & circulation 20120301
A rare coronary anomaly: atypical double right coronary artery with an acute inferior myocardial infarction. Korean circulation journal 20120301
Acute myocardial infarction during the early postpartum period successfully treated with tirofiban. European review for medical and pharmacological sciences 20120301
Contemporary use of glycoprotein IIb/IIIa inhibitors. Thrombosis and haemostasis 20120201
[Effect of early high-loading-dose tirofiban on platelet activity in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention]. Zhonghua xin xue guan bing za zhi 20120201
Intra-arterial thrombolysis using double devices: mechanicomechanical or chemicomechanical techniques. Journal of Korean Neurosurgical Society 20120201
Tailoring of integrin ligands: probing the charge capability of the metal ion-dependent adhesion site. Journal of medicinal chemistry 20120126
Intracoronary bolus-only compared with intravenous bolus plus infusion of tirofiban application in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120101
Sex-specific benefits of sirolimus-eluting stent on long-term outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: insights from the Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarction Study trial. American heart journal 20120101
Recent advances in epidural analgesia. Anesthesiology research and practice 20120101
IC bolus only versus IV with infusion 2b/3a inhibitors during STEMIs having PCI. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120101
Microembolus detection by transcranial Doppler sonography: review of the literature. Stroke research and treatment 20120101
A novel treatment for embolising carotid dissection. International journal of surgery case reports 20120101
Efficacy and safety of enoxaparin versus unfractionated heparin during percutaneous coronary intervention: systematic review and meta-analysis. BMJ (Clinical research ed.) 20120101
Direct intracoronary delivery of tirofiban during primary percutaneous coronary intervention for ST-elevation myocardial infarction. Chinese medical journal 20120101
Increased atherothrombotic burden in patients with diabetes mellitus and acute coronary syndrome: a review of antiplatelet therapy. Cardiology research and practice 20120101
Paroxysmal atrial fibrillation triggered by a monomorphic ventricular couplet in a patient with acute coronary syndrome. Indian pacing and electrophysiology journal 20120101
[Coronary optical coherence tomography in late stent thrombosis: the first application in Turkey]. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20120101
Outcome of the HORIZONS-AMI trial: bivalirudin enhances long-term survival in patients with ST-elevation myocardial infarction undergoing angioplasty. Vascular health and risk management 20120101
Tirofiban-induced diffuse alveolar hemorrhage: after primary angioplasty. Texas Heart Institute journal 20120101
Platelet function in stored heparinised autologous blood is not superior to in patient platelet function during routine cardiopulmonary bypass. PloS one 20120101
The avantgarde carbostent in patients scheduled for undelayable noncardiac surgery. Thrombosis 20120101
Integrins and their extracellular matrix ligands in lymphangiogenesis and lymph node metastasis. International journal of cell biology 20120101
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A cost-utility analysis of transcatheter aortic valve implantation in Belgium: focusing on a well-defined and identifiable population. BMJ open 20120101
Summary of product characteristics (SmPC)--study on utilization of information presented in SmPC by different groups of physicians. Acta poloniae pharmaceutica 20120101
Treatment of endovascular coil and stent migration using the merci retriever: report of three cases. Case reports in medicine 20120101
Surface modification of biomaterials: a quest for blood compatibility. International journal of biomaterials 20120101
Macrophage migration inhibitory factor is enhanced in acute coronary syndromes and is associated with the inflammatory response. PloS one 20120101
[Coronary stenting and surgery: perioperative management of antiplatelet therapy in patients undergoing surgery after coronary stent implantation]. Giornale italiano di cardiologia (2006) 20120101
[Tirofiban improved the prognosis of senior acute coronary syndrome patients received percutaneous coronary intervention]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20111201
Intra-arterial tirofiban infusion for partial recanalization with stagnant flow in hyperacute cerebral ischemic stroke. Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences 20111201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Staged Complete Revascularization in ST-Segment Elevation Myocardial Infarction Should Be the Treatment of Choice Compared to Primary Complete Revascularization. Korean circulation journal 20111201
Genetic determinants of platelet response to clopidogrel. Journal of thrombosis and thrombolysis 20111101
Current issues with glycoprotein IIb-IIIa antagonists. Current drug targets 20111101
Overcoming limitations of current antiplatelet drugs: a concerted effort for more profitable strategies of intervention. Annals of medicine 20111101
Management of patients with recently implanted coronary stents on dual antiplatelet therapy who need to undergo major surgery. Journal of thrombosis and haemostasis : JTH 20111101
Meta-analysis of randomized controlled trials of intracoronary versus intravenous administration of glycoprotein IIb/IIIa inhibitors during percutaneous coronary intervention for acute coronary syndrome. The American journal of cardiology 20111101
Enoxaparin-associated giant retroperitoneal hematoma in pulmonary embolism treatment. North American journal of medical sciences 20111101
Optimal use of platelet glycoprotein IIb/IIIa receptor antagonists in patients undergoing percutaneous coronary interventions. Drugs 20111022
Non-ST-segment elevation myocardial infarction in a patient with essential thrombocythemia treated with glycoprotein IIb/IIIa inhibitor: a case report. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20111001
Anti-platelet therapy: ADP receptor antagonists. British journal of clinical pharmacology 20111001
Intra-arterial adjuvant tirofiban after unsuccessful intra-arterial thrombolysis of acute ischemic stroke: preliminary experience in 16 patients. Neuroradiology 20111001
RGD mimetics containing phthalimidine fragment as novel ligands of fibrinogen receptor. Bioorganic & medicinal chemistry letters 20111001
Bridging therapy for early surgery in patients on dual antiplatelet therapy after drug-eluting stent implantation. Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20111001
Acute thrombus formation on an Amplatzer device during transcatheter closure of an atrial septal defect in a patient with homozygous factor V Leiden mutation. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20111001
Comparison of tirofiban combined with dalteparin or unfractionated heparin in primary percutaneous coronary intervention of acute ST-segment elevation myocardial infarction patients. Chinese medical journal 20111001
Repair and reconstruction of a resected tumor defect using a composite of tissue flap-nanotherapeutic-silk fibroin and chitosan scaffold. Annals of biomedical engineering 20110901
Dual oral antiplatelet therapy and unplanned surgery: possible role for intravenous platelet glycoprotein receptor inhibitors. Journal of cardiovascular medicine (Hagerstown, Md.) 20110901
Safety of Tirofiban in acute Ischemic Stroke: the SaTIS trial. Stroke 20110901
Advanced assessment of platelet function during adult donor care. Progress in transplantation (Aliso Viejo, Calif.) 20110901
Acute Cerebral Infarction Following Intravenous Glycoprotein IIb/IIIa Inhibitor for Acute Myocardial Infarction. Korean circulation journal 20110901
The antithrombotic activity of EP224283, a neutralizable dual factor Xa inhibitor/glycoprotein IIbIIIa antagonist, exceeds that of the coadministered parent compounds. The Journal of pharmacology and experimental therapeutics 20110801
Delineating the roles of the GPIIb/IIIa and GP-Ib-IX-V platelet receptors in mediating platelet adhesion to adsorbed fibrinogen and albumin. Biomaterials 20110801
The impact of age on effects of pre-hospital initiation of high bolus dose of tirofiban before primary angioplasty for ST-elevation myocardial infarction. Cardiovascular drugs and therapy 20110801
AMI on the move. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110801
Higher efficacy of pre-hospital tirofiban with longer pre-treatment time to primary PCI: protection for the negative impact of time delay. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110801
Upstream use of small-molecule glycoprotein iib/iiia inhibitors in patients with non-ST-segment elevation acute coronary syndromes: a systematic overview of randomized clinical trials. Circulation. Cardiovascular quality and outcomes 20110701
Safety and efficacy of tirofiban as adjunctive therapy for patients with ST-elevation myocardial infarction: a comparison versus placebo and abciximab. Cardiovascular & hematological agents in medicinal chemistry 20110701
Position of tirofiban in ST segment elevation myocardial infarction treatment: more than an adjunctive therapy. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110701
Minimal withdrawal of dual antiplatelet agents under the guidance of a point-of-care platelet activity assay early after drug-eluting stent implantation for surgical removal of renal cell carcinoma. International journal of cardiology 20110602
Controversies with On-TIME 2. Heart (British Cardiac Society) 20110601
A randomized two-by-two comparison of high-dose bolus tirofiban versus abciximab and unfractionated heparin versus bivalirudin during percutaneous coronary revascularization and stent placement: the tirofiban evaluation of novel dosing versus abciximab with clopidogrel and inhibition of thrombin (TENACITY) study trial. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601
Cannabis: a rare trigger of premature myocardial infarction. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20110501
Induction of integrin β3 in PGE₂-stimulated adhesion of mastocytoma P-815 cells to the Arg-Gly-Asp-enriched fragment of fibronectin. Biochemical pharmacology 20110401
Factor XIII supports platelet activation and enhances thrombus formation by matrix proteins under flow conditions. Journal of thrombosis and haemostasis : JTH 20110401
Long-term reduction of mortality in the 4-year follow up of tirofiban therapy in elective percutaneous coronary interventions (TOPSTAR) trial. The Journal of invasive cardiology 20110401
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Fibronectin upregulates cGMP-dependent protein kinase type Iβ through C/EBP transcription factor activation in contractile cells. American journal of physiology. Cell physiology 20110301
Traumatic dissection of a coronary artery: detection by multislice computed tomography and use of tirofiban as a reversible platelet inhibitor. Resuscitation 20110301
Comparison of Ezetimibe/Simvastatin 10/20 mg Versus Atorvastatin 20 mg in Achieving a Target Low Density Lipoprotein-Cholesterol Goal for Patients With Very High Risk. Korean circulation journal 20110301
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Heparin versus tirofiban in microvascular anastomosis: randomized controlled trial in a rat model. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 20110201
Humanized mouse model of thrombosis is predictive of the clinical efficacy of antiplatelet agents. Circulation 20110125
Upstream tirofiban reduces reperfusion cardiac arrhythmias in patients of acute ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. International journal of cardiology 20110121
Meta-analysis of randomized trials of glycoprotein IIb/IIIa inhibitors in high-risk acute coronary syndromes patients undergoing invasive strategy. The American journal of cardiology 20110115
Mechanical and chemical thrombolysis of cerebral sinus thrombosis: evolution of a technique. Journal of neurosurgery 20110101
Long-term efficacy of high-dose tirofiban versus double-bolus eptifibatide in patients undergoing percutaneous coronary intervention. Journal of cardiovascular medicine (Hagerstown, Md.) 20110101
Promoting regeneration of peripheral nerves in-vivo using new PCL-NGF/Tirofiban nerve conduits. Biomaterials 20110101
Circulating high sensitivity troponin T in severe sepsis and septic shock: distribution, associated factors, and relation to outcome. Intensive care medicine 20110101
High-dose tirofiban pretreatment reduces the need for bail-out study medication in patients with ST-segment elevation myocardial infarction: results of a subgroup analysis of the On-TIME 2 trial. Heart (British Cardiac Society) 20110101
Facilitated reperfusion with prehospital glycoprotein IIb/IIIa inhibition: predictors of complete ST-segment resolution before primary percutaneous coronary intervention in the On-TIME 2 trial: correlates of reperfusion before primary PCI. Journal of electrocardiology 20110101
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Persistent coronary no flow after wire insertion is an early and readily available mortality risk factor despite successful mechanical intervention in acute myocardial infarction: a pooled analysis from the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial JACC. Cardiovascular interventions 20110101
Prediction of 1-year clinical outcomes using the SYNTAX score in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a substudy of the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarc JACC. Cardiovascular interventions 20110101
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Upstream treatment of ST-segment elevation myocardial infarction: the role of glycoprotein IIb/IIIa inhibitors. The Canadian journal of cardiology 20110101
Oral antiplatelet therapy in diabetes mellitus and the role of prasugrel: an overview. Vascular health and risk management 20110101
Tirofiban use with clopidogrel and aspirin decreases adverse cardiovascular events after percutaneous coronary intervention for ST-elevation myocardial infarction: a meta-analysis of randomized trials. The Canadian journal of cardiology 20110101
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Severe thrombocytopenia following tirofiban infusion. Indian journal of pharmacology 20110101
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Alveolar hemorrhage following tirofiban treatment. A misleading diagnosis. Revista espanola de cardiologia 20101201
The golden hour of prehospital reperfusion with triple antiplatelet therapy: a sub-analysis from the Ongoing Tirofiban in Myocardial Evaluation 2 (On-TIME 2) trial early initiation of triple antiplatelet therapy. American heart journal 20101201
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Successful surgical management of massive pulmonary embolism during the second trimester in a parturient with heparin-induced thrombocytopenia. Interactive cardiovascular and thoracic surgery 20101101
Prehospital triple antiplatelet therapy in patients with acute ST elevation myocardial infarction leads to better platelet aggregation inhibition and clinical outcome than dual antiplatelet therapy. Heart (British Cardiac Society) 20101101
Pulmonary embolectomy in heparin-induced thrombocytopenia and thrombosis? Safety of heparin use. Interactive cardiovascular and thoracic surgery 20101101
Clinical benefit of low molecular weight heparin for ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention with glycoprotein IIb/IIIa inhibitor. Journal of Korean medical science 20101101
Perspective on coronary interventions & cardiac surgeries in India. The Indian journal of medical research 20101101
Role of biomarkers in risk stratification of acute coronary syndrome. The Indian journal of medical research 20101101
Snake venom disintegrins and cell migration. Toxins 20101101
Long-term clinical outcome based on aspirin and clopidogrel responsiveness status after elective percutaneous coronary intervention: a 3T/2R (tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel) trial substudy. Journal of the American College of Cardiology 20101026
[Efficiency and safety of thrombus aspiration plus intra-infarct-related artery administration of tirofiban during primary angioplasty]. Zhonghua xin xue guan bing za zhi 20101001
Safety evaluation of tirofiban. Expert opinion on drug safety 20100901
Balancing the benefits and risks of antiplatelet agents in patients with non-ST-segment elevated acute coronary syndromes and undergoing percutaneous coronary intervention. Journal of thrombosis and thrombolysis 20100801
Comparison of intracoronary versus intravenous administration of tirofiban in primary percutaneous coronary intervention. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20100801
Pharmacoinvasive strategy for ST-segment elevation myocardial infarction: wading through the treatment options. Circulation. Cardiovascular interventions 20100801
Role of the paclitaxel-eluting stent and tirofiban in patients with ST-elevation myocardial infarction undergoing postfibrinolysis angioplasty: the GRACIA-3 randomized clinical trial. Circulation. Cardiovascular interventions 20100801
Pre-hospital administration of tirofiban in diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: a sub-analysis of the On-Time 2 trial. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801
Comparison by meta-analysis of eptifibatide and tirofiban to abciximab in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention. The American journal of cardiology 20100715
Use of glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention: insights from the APEX-AMI trial. European heart journal 20100701
Randomised controlled trial evaluating the role of tirofiban in high-risk non-ST elevation acute coronary syndromes: an East Indian perspective. Singapore medical journal 20100701
Use of platelet glycoprotein IIb/IIIa inhibitors in diabetics undergoing PCI for non-ST-segment elevation acute coronary syndromes: impact of clinical status and procedural characteristics. Clinical research in cardiology : official journal of the German Cardiac Society 20100601
Anesthetic concerns for patients with coagulopathy. Current opinion in anaesthesiology 20100601
Early administration of small-molecule glycoprotein IIb/IIIa inhibitors before primary percutaneous coronary intervention for ST-elevation myocardial infarction: insights from randomized clinical trials. Journal of cardiovascular pharmacology and therapeutics 20100601
Tirofiban 'bridging' therapy for patients with drug-eluting stents undergoing non-cardiac surgery. British journal of anaesthesia 20100601
Effect of early, pre-hospital initiation of high bolus dose tirofiban in patients with ST-segment elevation myocardial infarction on short- and long-term clinical outcome. Journal of the American College of Cardiology 20100601
IIb or Not IIb: is there a place for pre-hospital tirofiban in ST-segment elevation myocardial infarction patients? Journal of the American College of Cardiology 20100601
Tirofiban shows better platelet inhibition in diabetic patients during PCI procedures. Cardiovascular journal of Africa 20100601
[Primary percutaneous coronary intervention in patients admitted with cardiogenic shock and ST-elevation myocardial infarction: prognosis and predictors of in-hospital mortality]. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20100601
Mechanism of platelet functional changes and effects of anti-platelet agents on in vivo hemostasis under different gravity conditions. Journal of applied physiology (Bethesda, Md. : 1985) 20100501
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Perfusion assessed by real-time contrast echocardiography correlates with clinical and echocardiographic parameters in patients with first STEMI treated with PCI - 6-month follow-up. Archives of medical science : AMS 20100430
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Characterization of static adhesion of human platelets in plasma to protein surfaces in microplates. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20090401
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Iron-induced platelet aggregation measurement: a novel method to measure platelet function in stenting for ST segment elevation myocardial infarction. European journal of clinical investigation 20090201
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Comparison of the effects of pretreatment with tirofiban, clopidogrel or both on the inhibition of platelet aggregation and activation in patients with acute coronary syndromes. Journal of thrombosis and thrombolysis 20090101
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Defining the role of platelet glycoprotein receptor inhibitors in STEMI: focus on tirofiban. Drugs 20090101
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Editorial on hypothesis and objectives in clinical trials: superiority, equivalence and non-inferiority. Thrombosis journal 20090101
Comparison of VerifyNow-P2Y12 test and Flow Cytometry for monitoring individual platelet response to clopidogrel. What is the cut-off value for identifying patients who are low responders to clopidogrel therapy? Thrombosis journal 20090101
Diabetes mellitus: a prothrombotic state implications for outcomes after coronary revascularization. Vascular health and risk management 20090101
First report of tirofiban-induced anemia (found in combination with severe thrombocytopenia). Texas Heart Institute journal 20090101
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Selecting the optimal antithrombotic regimen for patients with acute coronary syndromes undergoing percutaneous coronary intervention. Vascular health and risk management 20090101
Treatment of progressive stroke with tirofiban--experience in 35 patients. Cerebrovascular diseases (Basel, Switzerland) 20090101
In vitro inhibition of platelet aggregation in response to increasing concentrations of tirofiban in patients with significant renal insufficiency. The American heart hospital journal 20090101
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Review of the treatment of acute coronary syndrome in elderly patients. Clinical interventions in aging 20090101
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Facilitated PCI by combination fibrinolysis or upstream tirofiban in acute ST-segment elevation myocardial infarction: results of the Alteplase and Tirofiban in Acute Myocardial Infarction (ATAMI) trial. International journal of cardiology 20081112
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Rescue treatment with intra-arterial tirofiban infusion and emergent carotid stenting. Yonsei medical journal 20081031
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The in-vitro effect of tirofiban, glycoprotein IIb/IIIa antagonist, on various responses of porcine blood platelets. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080901
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Tailoring treatment with tirofiban in patients showing resistance to aspirin and/or resistance to clopidogrel (3T/2R). Rationale for the study and protocol design. Cardiovascular drugs and therapy 20080801
Successful treatment of rotary pump thrombus with the glycoprotein IIb/IIIa inhibitor tirofiban. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080801
Intra-arterial tirofiban infusion for thromboembolism during endovascular treatment of intracranial aneurysms. Neurosurgery 20080801
Treatment of acute myocardial infarction in pregnancy with coronary artery balloon angioplasty and stenting: use of tirofiban and clopidogrel. International journal of cardiology 20080721
Cerebellar hematoma complicating 600 mg loading dose of clopidogrel in combination with tirofiban. International journal of cardiology 20080721
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The effect of tirofiban on fibrinogen/agonist-induced platelet shape change and aggregation. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20080701
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A multicenter, randomized, open-label, therapeutic, and exploratory trial to evaluate the tolerability and efficacy of platelet glycoprotein IIb/IIIa receptor blocker (Clotinab) in high-risk patients with percutaneous coronary intervention. Yonsei medical journal 20080630
Transcranial Doppler ultrasonography-directed intravenous glycoprotein IIb/IIIa receptor antagonist therapy to control transient cerebral microemboli before and after carotid endarterectomy. The British journal of surgery 20080601
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The role of tirofiban in the management of coronary artery disease. Cardiovascular & hematological disorders drug targets 20080601
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Evaluation of triple anti-platelet therapy by modified thrombelastography in patients with acute coronary syndrome. Chinese medical journal 20080505
Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18. European heart journal 20080501
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Comparison of angioplasty with infusion of tirofiban or abciximab and with implantation of sirolimus-eluting or uncoated stents for acute myocardial infarction: the MULTISTRATEGY randomized trial. JAMA 20080416
E-page Original Images. Thrombotic lesion of saphenous vein graft resolved by antiaggregant therapy. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20080410
Efficacy and safety of argatroban with or without glycoprotein IIb/IIIa inhibitor in patients with heparin induced thrombocytopenia undergoing percutaneous coronary intervention for acute coronary syndrome. Journal of thrombosis and thrombolysis 20080401
Hypercoagulability due to homocystinuria in a case of head and neck reconstruction resolved with combined systemic therapy. Plastic and reconstructive surgery 20080401
Efficient tirofiban infusion resulting in resolution of intracoronary thrombus. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20080401
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Synthesis and biological evaluation of PEG-tirofiban conjugates. Bioorganic & medicinal chemistry letters 20080315
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Selective inhibition of the platelet phosphoinositide 3-kinase p110beta as promising new strategy for platelet protection during extracorporeal circulation. Thrombosis and haemostasis 20080301
Effects of coronary prestenting platelet inhibition on coronary poststenting inflammation. Journal of cardiovascular pharmacology 20080301
Abciximab: a reappraisal of its use in coronary care. Biologics : targets & therapy 20080301
Rescue use of tirofiban for acute carotid in-stent thrombosis. Yonsei medical journal 20080227
Application of high-throughput screening to identify a novel alphaIIb-specific small- molecule inhibitor of alphaIIbbeta3-mediated platelet interaction with fibrinogen. Blood 20080201
Effect of statin dose on incidence of atrial fibrillation: data from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) and Aggrastat to Zocor (A to Z) trials. American heart journal 20080201
High-dose tirofiban administered as bolus-only during percutaneous coronary intervention. The Journal of invasive cardiology 20080201
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Emergency coronary artery bypass grafting in patients with acute myocardial infarction treated with glycoprotein IIb/IIIa receptor inhibitors. International journal of cardiology 20080124
Change of white blood cell count more prognostic important than baseline values after primary percutaneous coronary intervention for ST elevation myocardial infarction. Thrombosis research 20080101
Long term tirofiban infusion before percutaneous coronary intervention in patients with angiographically massive intracoronary thrombus. Saudi medical journal 20080101
Effect of platelet glycoprotein IIb/IIIa receptor antagonist on survival of epigastric island flaps in rats with total venous occlusions. Scandinavian journal of plastic and reconstructive surgery and hand surgery 20080101
Platelet GPIIb/IIIa receptor antagonists in human ischemic brain disease. Current vascular pharmacology 20080101
Platelet anaesthesia during extracorporeal circulation: differential effects of GP IIb/IIIa blockers on platelet activation marker P-selectin expression at hypothermia. Thrombosis research 20080101
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Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis. Thrombosis research 20080101
Glycoprotein IIb/IIIa antagonists in acute ischaemic stroke: current status and future directions. Drugs 20080101
Glycoprotein IIb/IIIa inhibitors in patients with renal insufficiency undergoing percutaneous coronary intervention. Cardiology in review 20080101
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Short- and long-term outcomes of single bare metal stent versus drug eluting stent in nondiabetic patients with a simple de novo lesion in the middle and large vessel. Journal of translational medicine 20080101
Tirofiban preserves platelet loss during continuous renal replacement therapy in a randomised prospective open-blinded pilot study. Critical care (London, England) 20080101
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Does tirofiban prevent platelet loss in patients after cardiogenic shock during continuous renal replacement therapy? Critical care (London, England) 20080101
Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells. Cardiovascular diabetology 20080101
Platelet glycoprotein IIb/IIIa inhibitors in acute ischemic stroke. Neurology India 20080101
Reduced fibrin deposition and intravascular thrombosis in hDAF transgenic pig hearts perfused with tirofiban. Transplantation 20071227
Coronary embolism in a patient with mitral valve prosthesis: successful management with tirofiban and half-dose tissue-type plasminogen activator. Chinese medical journal 20071220
Routine upstream versus selective down stream use of tirofiban in non-ST elevation myocardial infarction patients scheduled for early invasive therapy; a randomized comparison. Journal of thrombosis and thrombolysis 20071201
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Ongoing tirofiban in myocardial infarction evaluation (On-TIME) 2 trial: rationale and study design. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20071101
Glycoprotein IIb/IIIa antagonists during carotid artery stenting: results from the carotid artery stenting (CAS) registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK). Clinical research in cardiology : official journal of the German Cardiac Society 20071001
Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials). The American journal of cardiology 20071001
Transfer with GP IIb/IIIa inhibitor tirofiban for primary percutaneous coronary intervention vs. on-site thrombolysis in patients with ST-elevation myocardial infarction (STEMI): a randomized open-label study for patients admitted to community hospitals. European heart journal 20071001
Prevention of microsurgical anastomotic thrombosis using aspirin, heparin, and the glycoprotein IIb/IIIa inhibitor tirofiban. Plastic and reconstructive surgery 20071001
Meta-analysis of clinical efficacy and bleeding risk with intravenous glycoprotein IIb/IIIa antagonists for percutaneous coronary intervention. The Canadian journal of cardiology 20071001
Selective inhibition of platelets by the GPIIb/IIIa receptor antagonist Tirofiban reduces leukocyte-endothelial cell interaction in murine antigen-induced arthritis. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20071001
Beta2-integrins and acquired glycoprotein IIb/IIIa (GPIIb/IIIa) receptors cooperate in NF-kappaB activation of human neutrophils. The Journal of biological chemistry 20070921
Pulmonary hemorrhage in a patient with acute coronary syndrome. AJR. American journal of roentgenology 20070901
Perioperative thrombotic risk of coronary artery stents: possible role for intravenous platelet blockade. Anesthesiology 20070901
Influence of preparative procedures on assay of platelet function and apparent effects of antiplatelet agents. The American journal of cardiology 20070815
Optimal platelet inhibition in patients undergoing PCI: data from the Multicenter Registry of High-Risk Percutaneous Coronary Intervention and Adequate Platelet Inhibition (MR PCI) study. American heart journal 20070801
Clinical results of two year dual antiplatelet therapy after primary percutaneous coronary intervention with paclitaxel-eluting stents: a single centre study. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20070801
Two-year clinical follow-up after sirolimus-eluting versus bare-metal stent implantation assisted by systematic glycoprotein IIb/IIIa Inhibitor Infusion in patients with myocardial infarction: results from the STRATEGY study. Journal of the American College of Cardiology 20070710
Two-by-two factorial comparison of high-bolus-dose tirofiban followed by standard infusion versus abciximab and sirolimus-eluting versus bare-metal stent implantation in patients with acute myocardial infarction: design and rationale for the MULTI-STRATEGY trial. American heart journal 20070701
Association of interleukin-10 level with increased 30-day mortality in patients with ST-segment elevation acute myocardial infarction undergoing primary coronary intervention. Circulation journal : official journal of the Japanese Circulation Society 20070701
The emerging role of platelet glycoprotein IIb/IIIa inhibitors in managing high-risk patients with non-ST segment elevation acute coronary syndromes. Current medical research and opinion 20070601
[Effects of intracoronary or intravenous tirofiban administration in patients with acute ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention]. Zhonghua xin xue guan bing za zhi 20070601
Timing of glycoprotein IIb/IIIa inhibitor use and outcomes among patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention (results from CRUSADE). The American journal of cardiology 20070515
A case of profound and prolonged tirofiban-induced thrombocytopenia and its correction by intravenous immunoglobulin G. Journal of thrombosis and haemostasis : JTH 20070501
[Absence of benefit with triple antiaggregation in acute non persistent ST segment elevation myocardial infarction in patients not subjected to early interventionism]. Medicina intensiva 20070501
Thrombus predicts ischemic complications during percutaneous coronary intervention in saphenous vein grafts: results from TARGET (do Tirofiban and ReoPro give similar efficacy trial?). Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070401
Ischemic coronary syndromes and SVG Interventions--do 2b/3a inhibitors miss the target? Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070401
Current strategies with high-dose tirofiban. Expert opinion on drug metabolism & toxicology 20070401
Evaluation on the safety and efficacy of tirofiban in the treatment of acute coronary syndrome. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070401
Enoxaparin injection for the treatment of high-risk patients with non-ST elevation acute coronary syndrome. Vascular health and risk management 20070401
AlphaIIbbeta3 priming and clustering by orally active and intravenous integrin antagonists. Journal of thrombosis and haemostasis : JTH 20070301
[Update on antithrombotic treatments in arterial diseases]. Revue medicale suisse 20070207
Bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitors in drug-eluting stent implantations in the absence of acute myocardial infarction: clinical and economic results. The Journal of invasive cardiology 20070201
Transvenous pacing causing tamponade in patients receiving glycoprotein IIb/IIIa inhibitors for percutaneous coronary intervention. The Journal of invasive cardiology 20070201
Activation of alphaIIbbeta3 is a sufficient but also an imperative prerequisite for activation of alpha2beta1 on platelets. Blood 20070115
The effects of tirofiban on peripheral markers of oxidative stress and endothelial dysfunction in patients with acute coronary syndromes. Thrombosis research 20070101
Effects of escalating doses of tirofiban on platelet aggregation and major receptor expression in diabetic patients: hitting the TARGET in the TENACITY trial? Thrombosis research 20070101
[Late localized aneurysmal dilations after sirolimus-eluting stents in 4 patients]. Zhonghua xin xue guan bing za zhi 20070101
Failure of recombinant factor VIIa in a patient with severe polymicrobial sepsis and postoperative uncontrolled intraabdominal bleeding. BMC infectious diseases 20070101
Evaluation of C-reactive protein, endothelin-1, adhesion molecule(s), and lipids as inflammatory markers in type 2 diabetes mellitus patients. Mediators of inflammation 20070101
Thrombin formation in vitro in response to shear-induced activation of platelets. Thrombosis research 20070101
The integrins. Genome biology 20070101
Hospital mortality in acute coronary syndrome: differences related to gender and use of percutaneous coronary procedures. BMC health services research 20070101
Utility of PFA-100 closure time vs. optical aggregometry in assessing the efficacy of platelet membrane glycoprotein IIb/IIIa antagonists in vitro. Clinical chemistry and laboratory medicine 20070101
[Protective effects of an inhibitor of glycoprotein IIb/IIIa in the hepatic and pulmonary disturbances secondary to ischemia and reperfusion injury of rat's liver]. Arquivos de gastroenterologia 20070101
Acute anterior myocardial infarction due to aortosaphenous vein graft occlusion with very large thrombus burden. Experimental and clinical cardiology 20070101
Value of platelet reactivity in predicting response to treatment and clinical outcome in patients undergoing primary coronary intervention: insights into the STRATEGY Study. Journal of the American College of Cardiology 20061205
Intravascular neutrophil activation due to carbon monoxide poisoning. American journal of respiratory and critical care medicine 20061201
The safety and efficacy of achieving very low LDL-cholesterol concentrations with high dose statin therapy. Current opinion in lipidology 20061201
Drug-eluting stents for ST[corrected]-elevation acute myocardial infarction: do we need randomized trials? Coronary artery disease 20061201
Safety and efficacy of low-dose unfractionated heparin during percutaneous coronary revascularisation and the relationship between activated clotting time and haemorrhagic or ischaemic complications: our results. Journal of cardiovascular medicine (Hagerstown, Md.) 20061201
Platelet microparticle formation and thrombin generation under high shear are effectively suppressed by a monoclonal antibody against GPIba. Thrombosis and haemostasis 20061201
Bivalirudin in percutaneous coronary intervention. Vascular health and risk management 20061201
Fondaparinux in the management of patients with ST-elevation acute myocardial infarction. Vascular health and risk management 20061201
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[Pathogenesis and therapy of the acute coronary syndrome: differentiated advantage of glycoprotein IIb/IIIa receptor antagonists for high-risk patients]. Deutsche medizinische Wochenschrift (1946) 20061124
Bolus-only platelet glycoprotein IIb-IIIa inhibition during percutaneous coronary intervention. The Journal of invasive cardiology 20061101
[Effect of pre-angiography use of tirofiban in patients with acute ST-elevation myocardial infarction treated by primary percutaneous coronary intervention]. Zhonghua xin xue guan bing za zhi 20061101
Iliac artery thrombosis after aortic balloon counterpulsation: treatment with intraarterial tirofiban, manual thrombectomy and stenting. International journal of cardiology 20061010
Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans. Circulation 20061010
Operator volume and outcomes of primary angioplasty for acute myocardial infarction in a single high-volume centre. Journal of cardiovascular medicine (Hagerstown, Md.) 20061001
[Platelet function after a high dose bolus of tirofiban immediately after coronary angioplasty]. Archives des maladies du coeur et des vaisseaux 20061001
Tirofiban-associated acute thrombocytopenia. Acta cardiologica 20061001
Sex differences in major bleeding with glycoprotein IIb/IIIa inhibitors: results from the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) initiative. Circulation 20060926
Evaluation of the National Cholesterol Education Program Adult Treatment Panel III algorithm for selecting candidates for statin therapy: insights from the A to Z trial. The American journal of cardiology 20060915
Role of abciximab in the treatment of coronary artery disease. Expert opinion on biological therapy 20060901
Mitigation of device-associated thrombosis and thromboembolism using combinations of heparin and tirofiban. The journal of extra-corporeal technology 20060901
Early invasive strategy improves outcomes in patients with acute coronary syndrome with previous coronary artery bypass graft surgery: a report from TACTICS-TIMI 18. Critical pathways in cardiology 20060901
Different effects of tirofiban and aspirin plus clopidogrel on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion. Heart (British Cardiac Society) 20060801
Differential diagnosis and management of acute profound thrombocytopenia by tirofiban: a case report. Journal of thrombosis and thrombolysis 20060801
Efficient platelet delta-granule release induced by [Ca2+]i elevation is modulated by GPIIbIIIa. International journal of molecular medicine 20060801
Complementary effects of sirolimus-eluting stents and glycoprotein IIb/IIIa inhibitors for percutaneous coronary intervention in diabetic patients: one-year follow up of a single-centre registry. Heart (British Cardiac Society) 20060801
Is transport with platelet GP IIb/IIIa inhibition for primary percutaneous coronary intervention more efficient than on-site thrombolysis in patients with STEMI admitted to community hospitals? Randomised study. Early results. Kardiologia polska 20060801
Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial. Circulation 20060725
Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets. Circulation research 20060707
Use of heparin upon reoperation in a pediatric patient with heparin-induced thrombocytopenia after disappearance of antibodies. Clinical research in cardiology : official journal of the German Cardiac Society 20060701
In vitro effect of the potent poly(ADP-ribose) polymerase (PARP) inhibitor INO-1001 alone and in combination with aspirin, eptifibatide, tirofiban, enoxaparin or alteplase on haemostatic parameters. Life sciences 20060620
Delayed stenting of a thrombotic saphenous vein graft after intravenous tirofiban pretreatment. International journal of cardiology 20060607
A comparison of dual vs. triple antiplatelet therapy in patients with non-ST-segment elevation acute coronary syndrome: results of the ELISA-2 trial. European heart journal 20060601
Outcome of multivessel coronary intervention in the contemporary percutaneous revascularization era. The American journal of cardiology 20060601
Utility of a whole blood single platelet counting assay to monitor the effects of tirofiban in patients with acute coronary syndromes scheduled for coronary intervention. Thrombosis and haemostasis 20060601
Platelet function monitoring with the Sonoclot analyzer after in vitro tirofiban and heparin administration. The Journal of thoracic and cardiovascular surgery 20060601
Role of tirofiban in treatment of stent thrombosis. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20060601
Acute coronary embolism after mitral valve replacement in a patient presenting with non-ST-segment elevation myocardial infarction. Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20060601
Feasibility and benefit of prehospital diagnosis, triage, and therapy by paramedics only in patients who are candidates for primary angioplasty for acute myocardial infarction. American heart journal 20060601
Collagen XVII promotes integrin-mediated squamous cell carcinoma transmigration--a novel role for alphaIIb integrin and tirofiban. Experimental cell research 20060501
Angiographic and clinical outcome in ST-segment elevation myocardial infarction patients receiving an adjunctive double bolus regimen of tirofiban for primary percutaneous coronary intervention. Circulation journal : official journal of the Japanese Circulation Society 20060501
Platelet microaggregation inhibition in patients with acute myocardial infarction pretreated with tirofiban and relationship with angiographic and clinical outcome. American heart journal 20060501
[Acute coronary syndrome: peri-interventional antithrombotic therapy]. Hamostaseologie 20060501
Platelets enhance CD4+ lymphocyte adhesion to extracellular matrix under flow conditions: role of platelet aggregation, integrins, and non-integrin receptors. Thrombosis and haemostasis 20060501
Association of a history of systemic hypertension with mortality, thrombotic, and bleeding complications following non-ST-segment elevation acute coronary syndrome. Journal of clinical hypertension (Greenwich, Conn.) 20060501
[Statistical notes. Which risks do the patient incur if his own cardiologist accepts to be involved in a clinical trial without deep consideration of the a priori available evidence?]. Giornale italiano di cardiologia (2006) 20060501
Comparison of abciximab with 'high-dose' tirofiban in patients undergoing percutaneous coronary intervention. International journal of cardiology 20060428
Is delayed facilitated percutaneous coronary intervention better than immediate in reperfused myocardial infarction? Six months follow up findings. Journal of thrombosis and thrombolysis 20060401
Tirofiban (Aggrastat) protects platelets and decreases platelet-granulocyte binding in an extracorporeal circulation model. The Thoracic and cardiovascular surgeon 20060401
Fluorescent microspheres reveal different regional blood flow in hyperacutely rejected nontransgenic and hDAF pig hearts. Transplantation proceedings 20060401
A fibrin encapsulated liposomes-in-chitosan matrix (FLCM) for delivering water-soluble drugs. Influences of the surface properties of liposomes and the crosslinked fibrin network. International journal of pharmaceutics 20060327
Successful lysis of coronary thrombi by long term warfarin treatment after a failed course of tirofiban infusion. International journal of cardiology 20060322
A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22. Circulation 20060321
Direct comparison of the A to Z and PROVE IT trials: a second chance to gain a first impression. Circulation 20060321
Thrombocytopenia associated with the use of GPIIb/IIIa inhibitors: position paper of the ISTH working group on thrombocytopenia and GPIIb/IIIa inhibitors. Journal of thrombosis and haemostasis : JTH 20060301
Abciximab-associated thrombocytopenia after previous tirofiban-related thrombocytopenia. Pharmacotherapy 20060301
Adding tirofiban to standard pretreatment does not alter outcomes for people with non ST-elevation ACS undergoing early invasive therapy. Evidence-based cardiovascular medicine 20060301
Single high-dose bolus tirofiban with high-loading-dose clopidogrel in primary coronary angioplasty. Heart and vessels 20060301
Use of glycoprotein IIb/IIIa inhibitors in invasively-treated patients with non-ST elevation acute coronary syndrome. Journal of cardiovascular medicine (Hagerstown, Md.) 20060301
Platelet inhibitors in non-ST-segment elevation acute coronary syndromes and percutaneous coronary intervention: glycoprotein IIb/IIIa inhibitors, clopidogrel, or both? Vascular health and risk management 20060301
Downstream administration of a high-dose tirofiban bolus in high-risk patients with unstable angina undergoing early percutaneous coronary intervention. International journal of cardiology 20060215
Variability in extent of platelet function inhibition after administration of optimal dose of glycoprotein IIb/IIIa receptor blockers in patients undergoing a high-risk percutaneous coronary intervention. The American journal of cardiology 20060215
Randomized comparison of upstream tirofiban versus downstream high bolus dose tirofiban or abciximab on tissue-level perfusion and troponin release in high-risk acute coronary syndromes treated with percutaneous coronary interventions: the EVEREST trial. Journal of the American College of Cardiology 20060207
The role of risk stratification in the decision to provide upstream versus selective glycoprotein IIb/IIIa inhibitors for acute coronary syndromes: a cost-effectiveness analysis. Journal of the American College of Cardiology 20060207
Upstream/downstream glycoprotein IIb/IIIa in non-ST-segment elevation myocardial infarction. Journal of the American College of Cardiology 20060207
Increased ability of tirofiban to maintain its inhibitory effects on the binding of fibrinogen to platelets in blood from patients with and without diabetes mellitus. Coronary artery disease 20060201
Frequency and management of thrombocytopenia with the glycoprotein IIb/IIIa receptor antagonists. The American journal of cardiology 20060201
Dependence of platelet thrombus stability on sustained glycoprotein IIb/IIIa activation through adenosine 5'-diphosphate receptor stimulation and cyclic calcium signaling. Journal of the American College of Cardiology 20060103
Differential inhibitory effects of platelet glycoprotein IIb/IIIa antagonists on aggregation induced by procoagulant agonists. Thrombosis research 20060101
Upregulation of GP IIb/IIIa receptors during platelet activation: influence on efficacy of receptor blockade. Thrombosis research 20060101
Are tirofiban and abciximab identical in efficacy? European heart journal 20060101
Tirofiban for the treatment of ischaemic stroke. Expert opinion on pharmacotherapy 20060101
Effect of tirofiban therapy on ST segment resolution and clinical outcomes in patients with ST segment elevated acute myocardial infarction undergoing primary angioplasty. Cardiology 20060101
Effects of abciximab on key pattern of human coronary restenosis in vitro: impact of the SI/MPL-ratio. BMC cardiovascular disorders 20060101
Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysis. BMC medical research methodology 20060101
Impacts of glycoprotein IIb/IIIa inhibition on QT dispersion after successful percutaneous coronary intervention. Angiology 20060101
Impact of early tirofiban administration on myocardial salvage in patients with acute myocardial infarction undergoing infarct-related artery stenting. Cardiology 20060101
Intraprocedural thrombus formation during coil placement in ruptured intracranial aneurysms: treatment with systemic application of the glycoprotein IIb/IIIa antagonist tirofiban. AJNR. American journal of neuroradiology 20060101
Changes in practice patterns affecting in-hospital and post-discharge survival among ACS patients. BMC health services research 20060101
Impact of on-site cardiac catheterization on resource utilization and fatal and non-fatal outcomes after acute myocardial infarction. BMC health services research 20060101
Acute ischaemic stroke treated with combined intra-arterial thrombolysis and intravenous tirofiban despite oral anticoagulant therapy at an international normalised ratio > or = 2.0. Internal and emergency medicine 20060101
[Use of heparin and platelet GPIIbIIIa inhibitor tirofiban for cardiac surgery in patients for suspicion of heparin-induced thrombocytopenia]. Annales francaises d'anesthesie et de reanimation 20060101
An audit of the use and complications of glycoprotein IIb/IIIa inhibitors in percutaneous coronary intervention against national UK standards. Cardiovascular revascularization medicine : including molecular interventions 20060101
A comparative study on the cost of new antibiotics and drugs of other therapeutic categories. PloS one 20060101
Effects of GP IIb/IIIa inhibitors on vascular inflammation, coronary microcirculation, and platelet function. Reviews in cardiovascular medicine 20060101
Tirofiban: a critical reappraisal of the clinical use, recent developments and future perspectives. Future cardiology 20060101
Microvascular obstruction after successful fibrinolytic therapy in acute myocardial infarction. Comparison of reteplase vs reteplase+abciximab: A cardiovascular magnetic resonance study. Heart international 20060101
Mortality at 1 year for the direct comparison of tirofiban and abciximab during percutaneous coronary revascularization: do tirofiban and ReoPro give similar efficacy outcomes at trial 1-year follow-up. European heart journal 20051201
Two distinct subgroups of tirofiban-induced thrombocytopenia exist due to drug dependent antibodies that cause platelet activation and increased ischaemic events. Platelets 20051201
Pharmacodynamics of two different dosing regimens of tirofiban in citrate or PPACK anticoagulated blood. Platelets 20051201
Successful use of recombinant factor VIIa in a patient with intractable bleeding during extracorporeal membrane oxygenation. The Thoracic and cardiovascular surgeon 20051201
Reduced dose tenecteplase plus tirofiban achieves similar TIMI 3 flow to full dose tenecteplase alone in acute myocardial infarction. Commentary. Evidence-based cardiovascular medicine 20051201
Current strategies with eptifibatide and other antiplatelet agents in percutaneous coronary intervention and acute coronary syndromes. Expert opinion on drug metabolism & toxicology 20051201
Are statins being underdosed in clinical practice? Data from TACTICS-TIMI 18. Critical pathways in cardiology 20051201
Cerebral ischemic infarction in paroxysmal nocturnal hemoglobinuria report of 2 cases and updated review of 7 previously published patients. Journal of neurology 20051101
Glycoprotein IIb/IIIa and P2Y12 receptor antagonists yield additive inhibition of platelet aggregation, granule secretion, soluble CD40L release and procoagulant responses. Platelets 20051101
Impact of ABO blood groups on tirofiban mediated inhibition of platelet function. Platelets 20051101
Tirofiban plus sirolimus-eluting stent vs abciximab plus bare-metal stent. JAMA 20051005
Tirofiban plus sirolimus-eluting stent vs abciximab plus bare-metal stent. JAMA 20051005
Tirofiban and emergency coronary surgery. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20051001
Intravenous tirofiban with intra-arterial urokinase and mechanical thrombolysis in stroke: preliminary experience in 11 cases. Stroke 20051001
Initial experience with a new femoral artery closure device following percutaneous coronary intervention with glycoprotein IIb/IIIa inhibition. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051001
Extending reperfusion therapy for acute ischemic stroke: emerging pharmacological, mechanical, and imaging strategies. Stroke 20051001
Early discharge is feasible following primary percutaneous coronary intervention with transradial stent implantation under platelet glycoprotein IIb/IIIa receptor blockade. Results of the AGGRASTENT Trial. The Journal of invasive cardiology 20051001
Effects of percutaneous coronary thrombectomy with the X-sizer catheter on epicardial flow and microvascular function in acute coronary syndromes. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20051001
Safety and feasibility of subcutaneous low molecular weight heparin for cerebral venous sinus thrombosis. Journal of clinical neurology (Seoul, Korea) 20051001
Effect of adjunctive treatment with tirofiban on troponin T elevation during stenting of critically stenosed aortocoronary saphenous vein grafts. The American journal of cardiology 20050901
Effects of tirofiban plus clopidogrel versus clopidogrel plus provisional abciximab on biomarkers of myocardial necrosis in patients with non-ST-elevation acute coronary syndromes treated with early aggressive approach. Results of the CLOpidogrel, upstream TIrofiban, in cath Lab Downstream Abciximab (CLOTILDA) study. American heart journal 20050901
Treatment of acute central retinal artery occlusionwith the platelet glycoprotein IIb/IIIa receptor inhibitor tirofiban. Thrombosis and haemostasis 20050901
Facilitated percutaneous coronary intervention (PCI) in patients with acute ST-elevation myocardial infarction: comparison of prehospital tirofiban versus fibrinolysis before direct PCI. International journal of cardiology 20050818
[Effects of anti-platelet drugs on myocardial no-reflow after acute myocardial infarction and reperfusion: experiment with mini-swine model]. Zhonghua yi xue za zhi 20050817
Impact of platelet glycoprotein IIb/IIIa Inhibition on the paclitaxel-eluting stent in patients with stable or unstable angina pectoris or provocable myocardial ischemia (a TAXUS IV substudy). The American journal of cardiology 20050815
Partial rescue of the perfusion deficit area by thrombolysis. Journal of magnetic resonance imaging : JMRI 20050801
A safety and feasibility report of combined direct thrombin and GP IIb/IIIa inhibition with bivalirudin and tirofiban in peripheral vascular disease intervention: treating critical limb ischemia like acute coronary syndrome. The Journal of invasive cardiology 20050801
Inflammatory response after intervention assessed by serial C-reactive protein measurements correlates with restenosis in patients treated with coronary stenting. American heart journal 20050801
ClfA(221-550), a fibrinogen-binding segment of Staphylococcus aureus clumping factor A, disrupts fibrinogen function. Thrombosis and haemostasis 20050801
The effect of glycoprotein IIIa PIA 1/A2 polymorphism on the PFA-100 response to GP IIb IIa receptor inhibitors-the importance of anticoagulants used. Journal of thrombosis and thrombolysis 20050801
Variation in the ability of glycoprotein IIb-IIIa antagonists to exert and maintain their inhibitory effects on the binding of fibrinogen. Journal of cardiovascular pharmacology 20050701
Compatibility of argatroban with abciximab, eptifibatide, or tirofiban during simulated Y-site administration. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050701
The effect of tirofiban on microvascular thrombosis: crush model. Plastic and reconstructive surgery 20050701
Tenecteplase and tirofiban in ST-segment elevation acute myocardial infarction: results of a randomized trial. American heart journal 20050701
Ability of different glycoprotein IIb-IIIa ligands to support platelet aggregation induced by activating antibody CRC54. Biochemistry. Biokhimiia 20050701
Glycoprotein IIb/IIIa inhibition reduces prothrombotic events under conditions of deep hypothermic circulatory arrest. Thrombosis and haemostasis 20050701
Stent thrombosis following bare-metal stent implantation: success of emergency percutaneous coronary intervention and predictors of adverse outcome. European heart journal 20050601
Comparison of enoxaparin versus heparin during elective percutaneous coronary intervention performed with either eptifibatide or tirofiban (the ACTION Trial). The American journal of cardiology 20050601
Simultaneous integrin alphavbeta3 and glycoprotein IIb/IIIa inhibition causes reduction in infarct size in a model of acute coronary thrombosis and primary angioplasty. Cardiovascular research 20050601
Safety of tirofiban therapy in korean patients with acute coronary syndrome. Circulation journal : official journal of the Japanese Circulation Society 20050601
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
The impact of GP IIb/IIIa inhibitors during primary percutaneous coronary intervention in acute myocardial infarction patients. The Journal of invasive cardiology 20050601
Platelet glycoprotein IIb/IIIa inhibition as adjunctive therapy during primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction. The Journal of invasive cardiology 20050601
The role of gender and other factors as predictors of not receiving reperfusion therapy and of outcome in ST-segment elevation myocardial infarction. Journal of thrombosis and thrombolysis 20050601
Use of antiplatelet inhibitors in peripheral vascular interventions. Seminars in interventional radiology 20050601
Tirofiban and sirolimus-eluting stent vs abciximab and bare-metal stent for acute myocardial infarction: a randomized trial. JAMA 20050504
The effect of tirofiban and clopidogrel pretreatment on outcome of old saphenous vein graft stenting in patients with acute coronary syndromes. The Tohoku journal of experimental medicine 20050501
Delayed tirofiban-induced thrombocytopenia: two case reports. Journal of thrombosis and haemostasis : JTH 20050501
Impact of adjunctive tirofiban administration on myocardial perfusion and mortality in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction. Thrombosis and haemostasis 20050501
The relation of renal function to ischemic and bleeding outcomes with 2 different glycoprotein IIb/IIIa inhibitors: the do Tirofiban and ReoPro Give Similar Efficacy Outcome (TARGET) trial. American heart journal 20050501
Peripheral arterial disease, acute coronary syndromes, and early invasive management: the TACTICS TIMI 18 trial. Clinical cardiology 20050501
Analysis of bleeding complications associated with glycoprotein IIb/IIIa receptors blockade in patients with high-risk acute coronary syndromes: insights from the PRISM-PLUS study. International journal of cardiology 20050408
Hyperglycemia is an important predictor of impaired coronary flow before reperfusion therapy in ST-segment elevation myocardial infarction. Journal of the American College of Cardiology 20050405
Leukocyte-platelet aggregates in rat peripheral blood after ischemic stroke and reperfusion. Biological research for nursing 20050401
Anticoagulant and anti-platelet effects are maintained following coadministration of otamixaban, a direct factor Xa inhibitor, with tirofiban in healthy volunteers. Thrombosis and haemostasis 20050401
Choice of GPIIb/IIIa antagonist in percutaneous coronary intervention: how should economic criteria be factored in? Pharmacy world & science : PWS 20050401
Influence of race on death and ischemic complications in patients with non-ST-elevation acute coronary syndromes despite modern, protocol-guided treatment. Circulation 20050315
Is platelet function as measured by Thrombelastograph monitoring in whole blood affected by platelet inhibitors? The journal of extra-corporeal technology 20050301
Tirofiban in acute coronary syndromes. Expert review of cardiovascular therapy 20050301
Very early cardiac magnetic resonance imaging for quantification of myocardial tissue perfusion in patients receiving tirofiban before percutaneous coronary intervention for ST-elevation myocardial infarction. American heart journal 20050301
Ongoing clinical trials of the pleiotropic effects of statins. Vascular health and risk management 20050301
Long-term clinical outcomes of platelet glycoprotein IIb/IIIa inhibitor combined with low molecular weight heparin in patients with acute coronary syndrome. Circulation journal : official journal of the Japanese Circulation Society 20050201
Immune thrombocytopenia caused by glycoprotein IIb/IIIa inhibitors. Chest 20050201
Combination of a high bolus dose of tirofiban with half-dose thrombolytics for the treatment of subacute stent thrombosis. Acta cardiologica 20050201
Drug therapy during percutaneous coronary interventions in stable and unstable coronary artery disease: the Italian Drug Evaluation in Angioplasty (IDEA) study. Italian heart journal : official journal of the Italian Federation of Cardiology 20050201
Effects of tirofiban and statins on high-sensitivity C-reactive protein, interleukin-6, and soluble CD40 ligand following percutaneous coronary interventions in patients with stable coronary artery disease. The American journal of cardiology 20050115
[Spleen rupture in myocardial infarction after administration of GP IIb-IIIa-antagonists]. Deutsche medizinische Wochenschrift (1946) 20050107
Prognostic implications of elevated troponin in patients with suspected acute coronary syndrome but no critical epicardial coronary disease: a TACTICS-TIMI-18 substudy. Journal of the American College of Cardiology 20050104
Intra-arterial thrombolysis for acute ischemic stroke: preliminary experience with platelet glycoprotein IIb/IIIa inhibitors as adjunctive therapy. Neurosurgery 20050101
Effect of tirofiban on percutaneous coronary intervention-induced endothelial dysfunction in patients with stable coronary artery disease. The American journal of cardiology 20050101
Safety of tirofiban therapy in very old patients with acute coronary syndrome or non-Q-wave myocardial infarction. Journal of the American Geriatrics Society 20050101
Platelet glycoprotein IIb/IIIa receptor antagonists in non-ST segment elevation acute coronary syndromes: a review and guide to patient selection. Drugs 20050101
FK419, a novel nonpeptide GPIIb/IIIa antagonist, restores microvascular patency and improves outcome in the guinea-pig middle cerebral artery thrombotic occlusion model: comparison with tirofiban. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050101
Calpha-H...O = C hydrogen bonds contribute to the specificity of RGD cell-adhesion interactions. BMC structural biology 20050101
Functional characteristic of snake venom disintegrins: potential therapeutic implication. Current pharmaceutical design 20050101
Medical decision making with incomplete evidence--choosing a platelet glycoprotein IIbIIIa receptor inhibitor for percutaneous coronary interventions. Medical decision making : an international journal of the Society for Medical Decision Making 20050101
Combining the hDAF transgene with the GP IIb/IIIa inhibitor tirofiban improves heart performance and reduces myocardial damage following hyperacute rejection in an ex vivo perfusion model. Transplantation proceedings 20050101
Pharmacodynamics and pharmacokinetics of the platelet GPIIb/IIIa inhibitor tirofiban in patients undergoing percutaneous coronary intervention: implications for adjustment of tirofiban and clopidogrel dosage. Thrombosis research 20050101
Restoration of normal coronary flow with tirofiban by intracoronary administration for no-reflow phenomenon after stent deployment. International heart journal 20050101
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Abciximab was more effective than tirofiban in preventing ischemic events in patients having coronary stenting. ACP journal club 20020101
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Integrating cost-effectiveness evidence into clinical practice guidelines in Australia for acute myocardial infarction. The European journal of health economics : HEPAC : health economics in prevention and care 20020101
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Standardized ultrasound as a new method to induce platelet aggregation: evaluation, influence of lipoproteins and of glycoprotein IIb/IIIa antagonist tirofiban. European journal of ultrasound : official journal of the European Federation of Societies for Ultrasound in Medicine and Biology 20011201
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Comparison of GP IIB/IIIA inhibitors and their activity as measured by aggregometry, flow cytometry, single platelet counting, and the rapid platelet function analyzer. Journal of thrombosis and thrombolysis 20011001
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Dissociation of glycoprotein IIb/IIIa antagonists from platelets does not result in fibrinogen binding or platelet aggregation. Circulation 20010918
Differential inhibition of adenosine diphosphate- versus thrombin receptor-activating peptide-stimulated platelet fibrinogen binding by abciximab due to different glycoprotein IIb/IIIa activation kinetics. Blood 20010901
A risk score system for predicting adverse outcomes and magnitude of benefit with glycoprotein IIb/IIIa inhibitor therapy in patients with unstable angina pectoris. The American journal of cardiology 20010901
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Adjunctive therapies in the cath lab. Use of combination glycoprotein IIb/IIIa inhibitor and direct thrombin inhibitor drugs to support percutaneous coronary stent placement in a patient with renal insufficiency and heparin-induced thrombocytopenia. The Journal of invasive cardiology 20010901
Tirofiban therapy does not increase the risk of hemorrhage after emergency coronary surgery. The Journal of thoracic and cardiovascular surgery 20010901
Pharmacodynamic characterization of the interaction between abciximab or tirofiban with unfractionated or a low molecular weight heparin in healthy subjects. British journal of clinical pharmacology 20010901
Alternatives to unfractionated heparin for anticoagulation in cardiopulmonary bypass. Perfusion 20010901
Resolution of a spontaneous coronary artery thrombus with a new antiplatelet agent. International angiology : a journal of the International Union of Angiology 20010901
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Should patients with unstable coronary syndromes routinely undergo cardiac catheterization and appropriate revascularization? The Journal of family practice 20010901
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Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein IIb/IIIa (alphaIIb/beta3) receptor-directed platelet inhibition. American heart journal 20010801
The A-to-Z Trial: Methods and rationale for a single trial investigating combined use of low-molecular-weight heparin with the glycoprotein IIb/IIIa inhibitor tirofiban and defining the efficacy of early aggressive simvastatin therapy. American heart journal 20010801
Estimation of anti-platelet drugs on human platelet aggregation with a novel whole blood aggregometer by a screen filtration pressure method. British journal of pharmacology 20010801
Platelet glycoprotein IIb/IIIa-receptor inhibitors in patients with acute coronary syndromes or undergoing percutaneous coronary interventions: a review. Clinical therapeutics 20010801
Safety and efficacy of thrombolysis with alteplase (50 mg) plus tirofiban versus alteplase (100 mg) alone in acute myocardial infarction: preliminary findings. Italian heart journal : official journal of the Italian Federation of Cardiology 20010801
Randomized comparison of ticlopidine and clopidogrel after intracoronary stent implantation in a broad patient population. Circulation 20010731
Eptifibatide and 7E3, but not tirofiban, inhibit alpha(v)beta(3) integrin-mediated binding of smooth muscle cells to thrombospondin and prothrombin. Circulation 20010731
Diffuse alveolar hemorrhage after clopidogrel use. The Journal of invasive cardiology 20010701
Stability and compatibility of tirofiban hydrochloride during simulated Y-site administration with other drugs. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010701
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Use of ICHOR-platelet works to assess platelet function in patients treated with GP IIb/IIIa inhibitors. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20010701
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Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. The New England journal of medicine 20010621
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Future trials of antiplatelet agents in cardiac ischemia. The New England journal of medicine 20010621
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Quantification by flow cytometry of the efficacy of and interindividual variation of platelet inhibition induced by treatment with tirofiban and abciximab. Coronary artery disease 20010501
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Augmentation of in-vitro clot dissolution by low frequency high-intensity ultrasound combined with antiplatelet and antithrombotic drugs. Journal of thrombosis and thrombolysis 20010501
Inhibition of tissue factor-activated platelets by low-molecular-weight heparins and glycoprotein IIb/IIIa receptor antagonist. Thrombosis research 20010415
A comparative study of light transmission aggregometry and automated bedside platelet function assays in patients undergoing percutaneous coronary intervention and receiving abciximab, eptifibatide, or tirofiban. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20010401
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Impact of abciximab versus tirofiban on hospital length of stay for PCI patients. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20010301
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