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Dronedarone

CAS No.:
141626-36-0
Catalog Number:
AG001GPV
Molecular Formula:
C31H44N2O5S
Molecular Weight:
556.7565
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
99%
1 week
United States
$140
- +
50mg
99%
1 week
United States
$315
- +
Product Description
Catalog Number:
AG001GPV
Chemical Name:
Dronedarone
CAS Number:
141626-36-0
Molecular Formula:
C31H44N2O5S
Molecular Weight:
556.7565
MDL Number:
MFCD00910331
IUPAC Name:
N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide
InChI:
InChI=1S/C31H44N2O5S/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3/h13-18,23,32H,5-12,19-22H2,1-4H3
InChI Key:
ZQTNQVWKHCQYLQ-UHFFFAOYSA-N
SMILES:
CCCCc1oc2c(c1C(=O)c1ccc(cc1)OCCCN(CCCC)CCCC)cc(cc2)NS(=O)(=O)C
EC Number:
604-240-2
UNII:
JQZ1L091Y2
Properties
Complexity:
800  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
556.297g/mol
Formal Charge:
0
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
556.762g/mol
Monoisotopic Mass:
556.297g/mol
Rotatable Bond Count:
18  
Topological Polar Surface Area:
97.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
7.2  
Literature
Title Journal
The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone. Archives of toxicology 20180601
Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. Toxicological sciences : an official journal of the Society of Toxicology 20150601
Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224. Naunyn-Schmiedeberg's archives of pharmacology 20141201
Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents. Cardiovascular research 20141101
Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation. Toxicology 20140902
Discovery of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors (part I). European journal of medicinal chemistry 20140623
Inhibition of I(f) in the atrioventricular node as a mechanism for dronedarone's reduction in ventricular rate during atrial fibrillation. Heart rhythm 20131101
Dronedarone's inhibition of If current is the primary mechanism responsible for its bradycardic effect. Journal of cardiovascular electrophysiology 20130801
Mechanisms of hepatocellular toxicity associated with dronedarone--a comparison to amiodarone. Toxicological sciences : an official journal of the Society of Toxicology 20130201
Drug safety evaluation of dronedarone in atrial fibrillation. Expert opinion on drug safety 20121101
Dronedarone reduces arterial thrombus formation. Basic research in cardiology 20121101
Management of ventricular and atrial arrhythmias in humans: towards a patient-specific approach. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20121101
Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels. Naunyn-Schmiedeberg's archives of pharmacology 20121001
The emerging role of amiodarone and dronedarone in Chagas disease. Nature reviews. Cardiology 20121001
[Dronedarone in high-risk patients with atrial fibrillation : PALLAS study]. Der Internist 20121001
[New antiarrhythmic drugs for the treatment of atrial fibrillation]. Giornale italiano di cardiologia (2006) 20121001
[Update 2012: new European guidelines for atrial fibrillation]. MMW Fortschritte der Medizin 20120910
Atrial fibrillation and heart failure in the elderly. Heart failure reviews 20120901
Meta-analysis of cardiovascular outcomes with dronedarone in patients with atrial fibrillation or heart failure. The American journal of cardiology 20120815
Recent clinical trials in atrial fibrillation in hypertensive patients. Current hypertension reports 20120801
Cost-effectiveness of dronedarone in atrial fibrillation: results for Canada, Italy, Sweden, and Switzerland. Clinical therapeutics 20120801
Atrial fibrillation: new drugs, devices, and procedures. Cleveland Clinic journal of medicine 20120801
Virtual tissue engineering of the human atrium: modelling pharmacological actions on atrial arrhythmogenesis. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120716
A 73-year-old man with interstitial lung disease due to dronedarone. American journal of respiratory and critical care medicine 20120715
Flecainide suppresses defibrillator-induced storming in catecholaminergic polymorphic ventricular tachycardia. Pacing and clinical electrophysiology : PACE 20120701
Dronedarone prevents microcirculatory abnormalities in the left ventricle during atrial tachypacing in pigs. British journal of pharmacology 20120601
Chronic oral amiodarone but not dronedarone therapy increases ventricular defibrillation threshold during acute myocardial ischemia in a closed-chest animal model. Journal of cardiovascular pharmacology 20120601
Pleiotropic effects of dronedarone on ischemia/reperfusion injury in heart and brain. Cardiovascular drugs and therapy 20120601
Efficacy and safety profile of dronedarone in clinical practice. Preliminary results of the Magdeburg Dronedarone Registry. International journal of cardiology 20120531
Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation. The Cochrane database of systematic reviews 20120516
Celivarone for maintenance of sinus rhythm and conversion of atrial fibrillation/flutter. Journal of cardiovascular electrophysiology 20120501
[Dronedarone: a real innovation or a mere second-best choice? How to find the way among guidelines, regulatory agencies and daily clinical practice]. Giornale italiano di cardiologia (2006) 20120501
rac-Methyl 2-(2-formyl-4-nitro-phen-oxy)hexa-noate. Acta crystallographica. Section E, Structure reports online 20120501
PALLAS: limiting indications for dronedarone treatment of atrial fibrillation? Expert opinion on pharmacotherapy 20120401
Fatal lung toxic effects related to dronedarone use. Archives of internal medicine 20120326
Dronedarone use and fatal lung toxic effects? Archives of internal medicine 20120326
Antiarrhythmic drugs for the maintenance of sinus rhythm: risks and benefits. International journal of cardiology 20120322
Dronedarone in high-risk permanent atrial fibrillation. The New England journal of medicine 20120322
Dronedarone in high-risk permanent atrial fibrillation. The New England journal of medicine 20120322
Dronedarone in high-risk permanent atrial fibrillation. The New England journal of medicine 20120322
[Rhythm---control in atrial fibrillation]. MMW Fortschritte der Medizin 20120322
Review of contemporary antiarrhythmic drug therapy for maintenance of sinus rhythm in atrial fibrillation. Journal of cardiovascular pharmacology and therapeutics 20120301
[Atrial fibrillation : new anticoagulants and antiarrhythmic drugs]. Herz 20120301
Highlights of the American Heart Association Scientific Sessions 2011: a focus on ATLAS-TIMI 51, TRACER and PALLAS. Expert review of cardiovascular therapy 20120301
Dronedarone-current status in management of atrial fibrillation. Indian heart journal 20120301
[Prevention of cardioembolic stroke]. Neurologia (Barcelona, Spain) 20120301
Atrial fibrillation. Lancet (London, England) 20120218
Second chance for dronedarone after recent setback? Lancet (London, England) 20120218
Dronedarone: an overview. Annals of medicine 20120201
Electrophysiologic profile of dronedarone on the ventricular level: beneficial effect on postrepolarization refractoriness in the presence of rapid phase 3 repolarization. Journal of cardiovascular pharmacology 20120101
Dronedarone for the treatment of atrial fibrillation: a NICE single technology appraisal. PharmacoEconomics 20120101
Early experience using a left atrial appendage occlusion device in patients with atrial fibrillation. Yonsei medical journal 20120101
Benefit-risk assessment of current antiarrhythmic drug therapy of atrial fibrillation. Clinical cardiology 20120101
[Amiodarone and thyroid dysfunction]. Medicina 20120101
Atrial fibrillation: established and innovative methods of evaluation and treatment. Deutsches Arzteblatt international 20120101
Managing atrial fibrillation in the elderly: critical appraisal of dronedarone. Clinical interventions in aging 20120101
Toward a New Gold Standard for Early Safety: Automated Temperature-Controlled hERG Test on the PatchLiner. Frontiers in pharmacology 20120101
Temporal pattern and costs of rehospitalization in atrial fibrillation/atrial flutter patients with one or more additional risk factors. Journal of medical economics 20120101
Who protects physicians and patients from guidelines? Cardiology 20120101
Cost considerations in the management of atrial fibrillation - impact of dronedarone. ClinicoEconomics and outcomes research : CEOR 20120101
Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan. Substance abuse treatment, prevention, and policy 20120101
Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: recommendations for stroke prevention and rate/rhythm control. The Canadian journal of cardiology 20120101
[Update on current care guidelines: atrial fibrillation]. Duodecim; laaketieteellinen aikakauskirja 20120101
Costs and clinical consequences of suboptimal atrial fibrillation management. ClinicoEconomics and outcomes research : CEOR 20120101
Dronedarone for recurrent ventricular tachycardia: a real alternative? Indian pacing and electrophysiology journal 20120101
Heart rate and use of beta-blockers in stable outpatients with coronary artery disease. PloS one 20120101
Addressing the management of atrial fibrillation - a systematic review of the role of dronedarone. International journal of general medicine 20120101
Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration. Free radical biology & medicine 20111215
Dronedarone in atrial fibrillation--Jekyll and Hyde? The New England journal of medicine 20111215
Dronedarone in high-risk permanent atrial fibrillation. The New England journal of medicine 20111215
Safety of dronedarone (Multaq). The Medical letter on drugs and therapeutics 20111212
Reduction of cerebral infarct size by dronedarone. Cardiovascular drugs and therapy 20111201
[Who protects physicians and patients from guidelines?]. Deutsche medizinische Wochenschrift (1946) 20111201
Dronedarone: a new hope for stroke prevention in atrial fibrillation? American journal of cardiovascular drugs : drugs, devices, and other interventions 20111201
Dronedarone and the incidence of stroke in patients with paroxysmal or persistent atrial fibrillation: a systematic review and meta-analysis of randomized trials. American journal of cardiovascular drugs : drugs, devices, and other interventions 20111201
The management of patients with atrial fibrillation and dronedarone's place in therapy. Advances in therapy 20111201
Dronedarone trial stopped due to excess mortality. Prescrire international 20111201
[Atrial fibrillation. PALLAS study: when dronedarone becomes a risk]. MMW Fortschritte der Medizin 20111201
Atrial fibrillation: Dronedarone not suitable for patients with permanent AF. Nature reviews. Cardiology 20111129
Rationale and current perspective for early rhythm control therapy in atrial fibrillation. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20111101
Amiodarone impairs trafficking through late endosomes inducing a Niemann-Pick C-like phenotype. Biochemical pharmacology 20111101
Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111015
Management of atrial fibrillation by primary care physicians in Germany: baseline results of the ATRIUM registry. Clinical research in cardiology : official journal of the German Cardiac Society 20111001
Update on the management of atrial fibrillation: anticoagulation and medical therapy. Current cardiology reports 20111001
The hERG K(+) channel S4 domain L532P mutation: characterization at 37°C. Biochimica et biophysica acta 20111001
Drug-induced heart failure. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20111001
Evaluation of dronedarone use in the US patient population between 2009 and 2010: a descriptive study using a claims database. Clinical therapeutics 20111001
Dronedarone: liver damage and cardiac disorders. Negative harm-benefit balance. Prescrire international 20111001
Managing patients with ICD shocks and programming tachycardia therapies during acute heart failure syndromes. Heart failure reviews 20110901
Elevated international normalized ratio associated with use of dronedarone and warfarin. The Annals of pharmacotherapy 20110901
Update on anti-coagulation in atrial fibrillation. QJM : monthly journal of the Association of Physicians 20110901
Mixed learning algorithms and features ensemble in hepatotoxicity prediction. Journal of computer-aided molecular design 20110901
Severe docetaxel overdose induced by pharmacokinetic interaction with dronedarone. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820
Atrial-selective sodium channel block by dronedarone: sufficient to terminate atrial fibrillation? Naunyn-Schmiedeberg's archives of pharmacology 20110801
Impact of dronedarone on hospitalization burden in patients with atrial fibrillation: results from the ATHENA study. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110801
Hospitalization: a relevant endpoint in atrial fibrillation management? Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110801
Is antiarrhythmic treatment in the elderly different? a review of the specific changes. Drugs & aging 20110801
Acute liver failure associated with dronedarone. Circulation. Arrhythmia and electrophysiology 20110801
Atrial fibrillation: outpatient presentation and management. Circulation 20110705
Effects of dronedarone on clinical outcomes in patients with lone atrial fibrillation: pooled post hoc analysis from the ATHENA/EURIDIS/ADONIS studies. Journal of cardiovascular electrophysiology 20110701
Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor. Molecular and cellular biochemistry 20110701
The impact of dronedarone on lone atrial fibrillation: perhaps not such a 'benign' arrhythmia? Journal of cardiovascular electrophysiology 20110701
Antiarrhythmic drugs for atrial fibrillation. Expert opinion on pharmacotherapy 20110601
Post-ATHENA and beyond. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20110601
Treating arrhythmias: an expert opinion. Expert opinion on pharmacotherapy 20110601
Reduction of myocardial infarct size by dronedarone in pigs--a pleiotropic action? Cardiovascular drugs and therapy 20110601
Prevention of atrial fibrillation complications with antiarrhythmic drugs: still an unmet need in clinical practice. Expert opinion on pharmacotherapy 20110601
Atrial fibrillation: epidemiology, prognosis and therapy. Minerva medica 20110601
Dronedarone for atrial fibrillation therapy. Expert review of cardiovascular therapy 20110601
Effect of triiodothyronine on antidepressant screening tests in mice and on presynaptic 5-HT1A receptors: mediation by thyroid hormone α receptors. The Journal of pharmacology and experimental therapeutics 20110501
Comment: worsening heart failure in the setting of dronedarone initiation. The Annals of pharmacotherapy 20110501
Methyl 4-(3-chloro-prop-oxy)benzoate. Acta crystallographica. Section E, Structure reports online 20110501
Effect of dronedarone on Na+, Ca2+ and HCN channels. Naunyn-Schmiedeberg's archives of pharmacology 20110401
Rhythm- and rate-controlling effects of dronedarone in patients with atrial fibrillation (from the ATHENA trial). The American journal of cardiology 20110401
Antiarrhythmic drugs management in patients with atrial fibrillation: the new guidelines. Minerva cardioangiologica 20110401
In brief: FDA warning on dronedarone (Multaq). The Medical letter on drugs and therapeutics 20110307
Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301
Mixed treatment comparisons for atrial fibrillation: evidence network or bewildering entanglement? Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301
Dronedarone for atrial fibrillation: How does it compare with amiodarone? Cleveland Clinic journal of medicine 20110301
Delayed and indirect effects of antiarrhythmic drugs in reducing sudden cardiac death. Future cardiology 20110301
[Perspectives and recommendations for the anti-arrhythmic treatment of atrial fibrillation: focus on dronedarone]. Revue medicale de Liege 20110301
Suppression of ventricular tachycardia with dronedarone: a case report. Journal of cardiovascular electrophysiology 20110201
A patient with recurrent atrial fibrillation and monomorphic ventricular tachycardia treated successfully with dronedarone. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110201
Atrial fibrillation: what have recent trials taught us regarding pharmacologic management of rate and rhythm control? Pacing and clinical electrophysiology : PACE 20110201
Targeting the arrhythmogenic substrate in atrial fibrillation: focus on structural remodeling. Current drug targets 20110201
Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110201
The pharmaceutical pipeline for atrial fibrillation. Annals of medicine 20110201
[Epidemiology, clinical picture and management of atrial fibrillation]. Der Nervenarzt 20110201
An important indirect drug interaction between dronedarone and warfarin that may be extrapolated to other drugs that can alter gastrointestinal function. American heart journal 20110201
What's new in...atrial fibrillation. Is dronedarone more effective than amiodarone? JAAPA : official journal of the American Academy of Physician Assistants 20110201
Dronedarone. Drugs of today (Barcelona, Spain : 1998) 20110201
Ethyl 2-(2-hy-droxy-5-nitro-phen-yl)acetate. Acta crystallographica. Section E, Structure reports online 20110201
Dronedarone as a new treatment option for atrial fibrillation patients: pharmacokinetics, pharmacodynamics and clinical practice. Expert opinion on pharmacotherapy 20110101
2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (Updating the 2006 Guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Heart rhythm 20110101
Sinus rhythm restoration and treatment success: insight from recent clinical trials. Clinical cardiology 20110101
Dronedarone: current evidence for its safety and efficacy in the management of atrial fibrillation. Drug design, development and therapy 20110101
Electrophysiology and adult congenital heart disease: advances and options. Progress in cardiovascular diseases 20110101
Comparing the 2010 North American and European atrial fibrillation guidelines. The Canadian journal of cardiology 20110101
Canadian Cardiovascular Society atrial fibrillation guidelines 2010: rate and rhythm management. The Canadian journal of cardiology 20110101
An Observational, Prospective Survey Assessing the Control of Atrial Fibrillation in Asia Pacific: Rationale and Design of the RecordAF-AP Registry. Clinical Medicine Insights. Cardiology 20110101
Dronedarone for the management of atrial fibrillation. Swiss medical weekly 20110101
Cost of AF Ablation: Where Do We Stand? Cardiology research and practice 20110101
[The research practice of anti-arrhythmic agents targeting on potassium ion channel]. Yao xue xue bao = Acta pharmaceutica Sinica 20110101
The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation. Vascular health and risk management 20110101
[Update on current care guidelines: atrial fibrillation]. Duodecim; laaketieteellinen aikakauskirja 20110101
[The role of dronedarone in the contemporary atrial fibrillation treatment]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20110101
Incidence of atrial fibrillation in patients with either heart failure or acute myocardial infarction and left ventricular dysfunction: a cohort study. BMC cardiovascular disorders 20110101
Pharmacological management of atrial fibrillation: one, none, one hundred thousand. Cardiology research and practice 20110101
[Amiodarone and thyroid function]. Kardiologia polska 20110101
Combination ranolazine and dronedarone to suppress atrial fibrillation. Reviews in cardiovascular medicine 20110101
Management of patients with atrial fibrillation: specific considerations for the old age. Cardiology research and practice 20110101
Incidence and severity of coronary artery disease in patients with atrial fibrillation undergoing first-time coronary angiography. PloS one 20110101
Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter. Clinical Medicine Insights. Cardiology 20110101
[New drugs for small animals in 2010]. Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere 20110101
Dronedarone therapy in atrial fibrillation: a summary of recent controlled trials. Journal of cardiovascular pharmacology and therapeutics 20101201
Clinical pharmacology of dronedarone: implications for the therapy of atrial fibrillation. Journal of cardiovascular pharmacology and therapeutics 20101201
Effect of dronedarone on exercise capacity and cardiac function in patients with severe left ventricular dysfunction and compensated stable heart failure. Cardiovascular drugs and therapy 20101201
Dronedarone or amiodarone for rhythm control for atrial fibrillation: implications from the DIONYSOS study. Expert opinion on pharmacotherapy 20101201
Treatment of atrial fibrillation in 2010 and beyond. Journal of cardiovascular pharmacology and therapeutics 20101201
A new agent for atrial fibrillation: electrophysiological properties of dronedarone. Journal of cardiovascular pharmacology and therapeutics 20101201
A review of the appropriate and inappropriate use of dronedarone: lessons learned from controlled studies and regulatory submission. Journal of cardiovascular pharmacology and therapeutics 20101201
Augmenting maintenance of sinus rhythm in the control of atrial fibrillation by antiarrhythmic drug combinations. Journal of cardiovascular pharmacology and therapeutics 20101201
[Dronedarone]. Herzschrittmachertherapie & Elektrophysiologie 20101201
[New developments in the antiarrhythmic therapy of atrial fibrillation]. Herzschrittmachertherapie & Elektrophysiologie 20101201
Are neurological and other side effects truly less frequent in dronedarone compared to amiodarone? Journal of cardiovascular electrophysiology 20101201
Advances in the treatment of atrial fibrillation. Minerva cardioangiologica 20101201
[Management of atrial fibrillation, what to know on old and new antiarrhythmics]. Annales de cardiologie et d'angeiologie 20101201
[Current management of atrial fibrillation: rhythm or rate control and thoughts about a new treatment paradigm]. Annales de cardiologie et d'angeiologie 20101201
Dronedarone for atrial fibrillation? Drug and therapeutics bulletin 20101101
Dronedarone for atrial fibrillation have we expanded the antiarrhythmic armamentarium? Journal of the American College of Cardiology 20101012
Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation. Journal of the American College of Cardiology 20101005
New approaches to atrial fibrillation management: treat the patient, not the ECG. Cardiovascular therapeutics 20101001
Dronedarone and vitamin K antagonists: a review of drug-drug interactions. American heart journal 20101001
Dronedarone for the treatment of atrial fibrillation and atrial flutter. Health technology assessment (Winchester, England) 20101001
[Treatment of atrial fibrillation: when to use drugs or to perform ablation]. Giornale italiano di cardiologia (2006) 20101001
Acute dronedarone is inferior to amiodarone in terminating and preventing atrial fibrillation in canine atria. Heart rhythm 20100901
Amiodarone and dronedarone: the worker bee and the drone? Heart rhythm 20100901
Worsening heart failure in the setting of dronedarone initiation. The Annals of pharmacotherapy 20100901
Role of dronedarone in atrial fibrillation: more questions than answers. Pharmacotherapy 20100901
Dronedarone: a new antiarrhythmic agent. Pharmacotherapy 20100901
Dronedarone: an alternative to amiodarone? The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20100901
[Advances in the prevention of cerebral ischaemia due to atrial fibrillation]. Neurologia (Barcelona, Spain) 20100901
The impact of new and emerging clinical data on treatment strategies for atrial fibrillation. Journal of cardiovascular electrophysiology 20100801
Prevention of stroke in patients with atrial fibrillation: the role of new antiarrhythmic and antithrombotic drugs. Cerebrovascular diseases (Basel, Switzerland) 20100801
Dronedarone: NICE enough? Expert review of cardiovascular therapy 20100801
Dronedarone in patients with atrial fibrillation. Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20100801
Dronedarone: where does it fit in the treatment of atrial fibrillation? South Dakota medicine : the journal of the South Dakota State Medical Association 20100801
Dronedarone. atrial fibrillation: too many questions about long-term adverse effects. Prescrire international 20100801
The dronedarone odyssey. Prescrire international 20100801
Dronedarone: a safety comparison to amiodarone. Current drug safety 20100702
Dronedarone in patients with congestive heart failure: insights from ATHENA. European heart journal 20100701
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study. Journal of cardiovascular electrophysiology 20100601
Dronedarone: an emerging therapy for atrial fibrillation. Therapeutic advances in cardiovascular disease 20100601
A perspective on DIONYSOS. Journal of cardiovascular electrophysiology 20100601
Dronedarone: a review of characteristics and clinical data. Critical pathways in cardiology 20100601
Thrombi of different pathologies: implications for diagnosis and treatment. Current treatment options in cardiovascular medicine 20100601
New and emerging antiarrhythmic and anticoagulant agents for atrial fibrillation. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100501
Antiarrhythmic and nonantiarrhythmic drugs for sudden cardiac death prevention. Journal of cardiovascular pharmacology 20100501
Cost burden of cardiovascular hospitalization and mortality in ATHENA-like patients with atrial fibrillation/atrial flutter in the United States. Clinical cardiology 20100501
Dronedarone for atrial fibrillation have we expanded the antiarrhythmic armamentarium? Journal of the American College of Cardiology 20100413
New antiarrhythmic drugs for treatment of atrial fibrillation. Lancet (London, England) 20100403
Comparative efficacy of dronedarone and amiodarone for the maintenance of sinus rhythm in patients with atrial fibrillation. Journal of the American College of Cardiology 20100309
Dronedarone is superior to placebo the case for optimism. Journal of the American College of Cardiology 20100309
The role of thyroid hormone nuclear receptors in the heart: evidence from pharmacological approaches. Heart failure reviews 20100301
Atrial Ca2+ signaling in atrial fibrillation as an antiarrhythmic drug target. Naunyn-Schmiedeberg's archives of pharmacology 20100301
Cardioversion of atrial fibrillation: the use of antiarrhythmic drugs. Heart (British Cardiac Society) 20100301
[Current antiarrhythmic drug therapy in atrial fibrillation]. Deutsche medizinische Wochenschrift (1946) 20100301
[Clinical profile of the new antiarrhythmic drug dronedarone]. Deutsche medizinische Wochenschrift (1946) 20100301
[Clinical pharmacology and electrophysiological properties of dronedarone]. Deutsche medizinische Wochenschrift (1946) 20100301
[Preventing stroke by treating atrial fibrillation--new hope with dronedarone and dabigatran?]. Deutsche medizinische Wochenschrift (1946) 20100301
FDA drug information that never reaches clinicians. The New England journal of medicine 20100211
Replacing aspirin and warfarin for secondary stroke prevention: is it worth the costs? Current opinion in neurology 20100201
Atrial fibrillation. DIONYSOS study comparing dronedarone with amiodarone. BMJ (Clinical research ed.) 20100119
Dronedarone: a novel antiarrhythmic agent for the treatment of atrial fibrillation. Current opinion in cardiology 20100101
Effects of amiodarone therapy on thyroid function. Nature reviews. Endocrinology 20100101
Efficacy and safety of dronedarone: a review of randomized trials. Expert opinion on drug safety 20100101
Dronedarone--a new alternative for management of atrial fibrillation. Recent patents on cardiovascular drug discovery 20100101
Atrial fibrillation: Dronedarone and amiodarone-the safety versus efficacy debate. Nature reviews. Cardiology 20100101
Dronedarone: current evidence and future questions. Cardiovascular therapeutics 20100101
[Comparison of dronedarone and amiodarone for the maintenance of sinus rhythm in patients with atrial fibrillation. Indirect meta-analysis]. Kardiologiia 20100101
Impact of dronedarone in atrial fibrillation and flutter on stroke reduction. Clinical interventions in aging 20100101
Forecasting drug utilization and expenditure in a metropolitan health region. BMC health services research 20100101
Significant sirolimus and dronedarone interaction in a kidney transplant recipient. The Annals of pharmacotherapy 20100101
Concept of the five 'A's for treating emergency arrhythmias. Journal of emergencies, trauma, and shock 20100101
Treating critical supraventricular and ventricular arrhythmias. Journal of emergencies, trauma, and shock 20100101
Beta1-adrenoceptor polymorphism predicts flecainide action in patients with atrial fibrillation. PloS one 20100101
[Ionic mechanisms of action of class III antiarrhythmic drugs]. Kardiologiia 20100101
Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia. Vascular health and risk management 20100101
Dronedarone for the treatment of atrial fibrillation and atrial flutter: approval and efficacy. Vascular health and risk management 20100101
Atrial fibrillation after cardiac surgery. Annals of cardiac anaesthesia 20100101
Dronedarone: evidence supporting its therapeutic use in the treatment of atrial fibrillation. Core evidence 20100101
Dronedarone: from buzz to reality. Archives of cardiovascular diseases 20100101
[New antiarrhythmic drugs for treatment of atrial fibrillation]. Duodecim; laaketieteellinen aikakauskirja 20100101
[Novel targets in the treatment of patients with atrial fibrillation: from elimination of symptoms to improvement of clinical outcomes]. Kardiologiia 20100101
The effect of acyclovir on the tubular secretion of creatinine in vitro. Journal of translational medicine 20100101
Dronedarone: a new therapeutic alternative for cardiac arrhythmias. Journal of young pharmacists : JYP 20100101
Amiodarone and thyroid. Best practice & research. Clinical endocrinology & metabolism 20091201
Recent advances in the pharmacological treatment of cardiac arrythmias. Drugs of today (Barcelona, Spain : 1998) 20091101
Dronedarone (Multaq) for atrial fibrillation. The Medical letter on drugs and therapeutics 20091005
Dronedarone: a promising alternative for the management of atrial fibrillation. Cardiovascular drugs and therapy 20091001
Rethinking the reasons to treat atrial fibrillation? The role of dronedarone in reducing cardiovascular hospitalizations. European heart journal 20091001
Dronedarone. Nature reviews. Drug discovery 20091001
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