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PEPA

CAS No.:
141286-78-4
Catalog Number:
AG001G65
Molecular Formula:
C16H16F2N2O4S2
Molecular Weight:
402.4360
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$190
- +
10mg
99%
1 week
United States
$257
- +
50mg
99%
1 week
United States
$923
- +
Product Description
Catalog Number:
AG001G65
Chemical Name:
PEPA
CAS Number:
141286-78-4
Molecular Formula:
C16H16F2N2O4S2
Molecular Weight:
402.4360
MDL Number:
MFCD04974493
IUPAC Name:
2-[4-[2-(benzenesulfonamido)ethylsulfanyl]-2,6-difluorophenoxy]acetamide
InChI:
InChI=1S/C16H16F2N2O4S2/c17-13-8-11(9-14(18)16(13)24-10-15(19)21)25-7-6-20-26(22,23)12-4-2-1-3-5-12/h1-5,8-9,20H,6-7,10H2,(H2,19,21)
InChI Key:
GTACSIONMHMRPD-UHFFFAOYSA-N
SMILES:
NC(=O)COc1c(F)cc(cc1F)SCCNS(=O)(=O)c1ccccc1
Properties
Complexity:
541  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
402.052g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
402.431g/mol
Monoisotopic Mass:
402.052g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
132A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.2  
Literature
Title Journal
Facilitating actions of an AMPA receptor potentiator upon extinction of contextually conditioned fear response in stressed mice. Neuroscience letters 20110125
Glutamatergic targets for enhancing extinction learning in drug addiction. Current neuropharmacology 20101201
The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration. Learning & memory (Cold Spring Harbor, N.Y.) 20100401
Pharmacological discrimination of extinction and reconsolidation of contextual fear memory by a potentiator of AMPA receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20091101
Facilitation of extinction learning for contextual fear memory by PEPA: a potentiator of AMPA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070103
Heterogeneity and potentiation of AMPA type of glutamate receptors in rat cultured microglia. Glia 20040701
Enhanced relative expression of glutamate receptor 1 flip AMPA receptor subunits in hippocampal astrocytes of epilepsy patients with Ammon's horn sclerosis. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040225
A desensitization-selective potentiator of AMPA-type glutamate receptors. British journal of pharmacology 20020801
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
The AMPA receptor allosteric potentiator PEPA ameliorates post-ischemic memory impairment. Neuroreport 20010917
AMPA-preferring receptors mediate excitatory non-NMDA responses of primate retinal ganglion cells. Visual neuroscience 20010101
Properties