β-D-Glucopyranose, diglycoside with (2R,3R)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-1,4-butanediol
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Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605). | International journal of molecular sciences 20160301 |
Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice. | Carcinogenesis 20160201 |
Identification and functional characterization of a flax UDP-glycosyltransferase glucosylating secoisolariciresinol (SECO) into secoisolariciresinol monoglucoside (SMG) and diglucoside (SDG). | BMC plant biology 20140101 |
Lignans in seeds of Linum species. | Phytochemistry 20121001 |
Evaluation of the efficacy of flaxseed meal and flaxseed extract in reducing menopausal symptoms. | Journal of medicinal food 20120901 |
Potential effects of lignan-enriched flaxseed powder on bodyweight, visceral fat, lipid profile, and blood pressure in rats. | Fitoterapia 20120701 |
[Effects of secoisolariciresinol diglucoside combined with bortezomib on induction of apoptosis in lung cancer cell line A549]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120201 |
Comparative effects of sesame seed lignan and flaxseed lignan in reducing the growth of human breast tumors (MCF-7) at high levels of circulating estrogen in athymic mice. | Nutrition and cancer 20120101 |
Role of bifidobacteria in the activation of the lignan secoisolariciresinol diglucoside. | Applied microbiology and biotechnology 20111001 |
Effect of flaxseed lignans added to milk or fed to cows on oxidative degradation of dairy beverages enriched with polyunsaturated fatty acids. | The Journal of dairy research 20110201 |
[Effects of flaxseed extract on rheological properties of blood in experimental ovariectomy]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
Natural products in regression and slowing of progression of atherosclerosis. | Current pharmaceutical biotechnology 20101201 |
Cytostatic inhibition of cancer cell growth by lignan secoisolariciresinol diglucoside. | Nutrition research (New York, N.Y.) 20101101 |
Health effects with consumption of the flax lignan secoisolariciresinol diglucoside. | The British journal of nutrition 20100401 |
Dietary flaxseed lignan or oil combined with tamoxifen treatment affects MCF-7 tumor growth through estrogen receptor- and growth factor-signaling pathways. | Molecular nutrition & food research 20100301 |
The effect of secoisolariciresinol diglucoside and flaxseed oil, alone and in combination, on MCF-7 tumor growth and signaling pathways. | Nutrition and cancer 20100101 |
Further studies on a human intestinal bacterium Ruminococcus sp. END-1 for transformation of plant lignans to mammalian lignans. | Journal of agricultural and food chemistry 20090826 |
Effects of the flaxseed lignans secoisolariciresinol diglucoside and its aglycone on serum and hepatic lipids in hyperlipidaemic rats. | The British journal of nutrition 20090801 |
Milk concentration of the mammalian lignan enterolactone, milk production, milk fatty acid profile, and digestibility in dairy cows fed diets containing whole flaxseed or flaxseed meal. | The Journal of dairy research 20090801 |
Determination of lignans in flaxseed using liquid chromatography with time-of-flight mass spectrometry. | Journal of chromatography. A 20090109 |
Patented techniques for the extraction and isolation of secoisolari-ciresinol diglucoside from flaxseed. | Recent patents on food, nutrition & agriculture 20090101 |
Regulation of zinc transporters by dietary flaxseed lignan in human breast cancer xenografts. | Molecular biology reports 20081201 |
Hydrolysis kinetics of secoisolariciresinol diglucoside oligomers from flaxseed. | Journal of agricultural and food chemistry 20081112 |
Validation of a reversed phase high performance thin layer chromatographic-densitometric method for secoisolariciresinol diglucoside determination in flaxseed. | Journal of chromatography. A 20081017 |
Flaxseed lignan attenuates high-fat diet-induced fat accumulation and induces adiponectin expression in mice. | The British journal of nutrition 20080901 |
Effect of feeding flax or linseed meal on progesterone clearance rate in ovariectomized ewes. | Domestic animal endocrinology 20080801 |
Metabolism of the lignan macromolecule into enterolignans in the gastrointestinal lumen as determined in the simulator of the human intestinal microbial ecosystem. | Journal of agricultural and food chemistry 20080625 |
Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects. | The British journal of nutrition 20080601 |
Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia. | Journal of medicinal food 20080601 |
Separation and determination of secoisolariciresinol diglucoside oligomers and their hydrolysates in the flaxseed extract by high-performance liquid chromatography. | Journal of chromatography. A 20080328 |
Regression of hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseed. | Atherosclerosis 20080301 |
Secoisolariciresinol diglucoside induces neovascularization-mediated cardioprotection against ischemia-reperfusion injury in hypercholesterolemic myocardium. | Journal of molecular and cellular cardiology 20080101 |
Antioxidant activities of the flaxseed lignan secoisolariciresinol diglucoside, its aglycone secoisolariciresinol and the mammalian lignans enterodiol and enterolactone in vitro. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071101 |
Enantioselective dehydroxylation of enterodiol and enterolactone precursors by human intestinal bacteria. | Biological & pharmaceutical bulletin 20071101 |
Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism. | Atherosclerosis 20070601 |
Feeding flaxseed oil but not secoisolariciresinol diglucoside results in higher bone mass in healthy rats and rats with kidney disease. | Prostaglandins, leukotrienes, and essential fatty acids 20070501 |
Purification of secoisolariciresinol diglucoside with column chromatography on a sephadex LH-20. | Journal of chromatographic science 20070401 |
AAPH-mediated antioxidant reactions of secoisolariciresinol and SDG. | Organic & biomolecular chemistry 20070221 |
Secoisolariciresinol diglucoside: relevance to angiogenesis and cardioprotection against ischemia-reperfusion injury. | The Journal of pharmacology and experimental therapeutics 20070201 |
Clostridium saccharogumia sp. nov. and Lactonifactor longoviformis gen. nov., sp. nov., two novel human faecal bacteria involved in the conversion of the dietary phytoestrogen secoisolariciresinol diglucoside. | Systematic and applied microbiology 20070101 |
Microwave-assisted extraction of the main phenolic compounds in flaxseed. | Phytochemical analysis : PCA 20070101 |
Effect of processing and storage on the stability of flaxseed lignan added to dairy products. | Journal of agricultural and food chemistry 20061115 |
Contribution of linseed intake to urine and serum enterolignan levels in German females: a randomised controlled intervention trial. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060701 |
Occurrence and activity of human intestinal bacteria involved in the conversion of dietary lignans. | Anaerobe 20060601 |
Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice. | Cancer letters 20060328 |
Phylogeny of human intestinal bacteria that activate the dietary lignan secoisolariciresinol diglucoside. | FEMS microbiology ecology 20060301 |
Effect of processing and storage on the stability of flaxseed lignan added to bakery products. | Journal of agricultural and food chemistry 20060111 |
Assessing exposure to lignans and their metabolites in humans. | Journal of AOAC International 20060101 |
Dietary secoisolariciresinol diglucoside and its oligomers with 3-hydroxy-3-methyl glutaric acid decrease vitamin E levels in rats. | The British journal of nutrition 20040701 |
The effects of dietary flaxseed on the Fischer 344 rat: II. Liver gamma-glutamyltranspeptidase activity. | Cell biochemistry and function 20040101 |
Antithrombic and anti-atherogenic effects of partially defatted flaxseed meal using a laser-induced thrombosis test in apolipoprotein E and low-density lipoprotein receptor deficient mice. | Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20031201 |
Exposure to flaxseed or its purified lignan during suckling inhibits chemically induced rat mammary tumorigenesis. | Experimental biology and medicine (Maywood, N.J.) 20030901 |
On-line liquid-chromatography-nuclear magnetic resonance spectroscopy-mass spectrometry coupling for the separation and characterization of secoisolariciresinol diglucoside isomers in flaxseed. | Journal of chromatography. A 20021004 |
Isolation of the lignan secoisolariciresinol diglucoside from flaxseed (Linum usitatissimum L.) by high-speed counter-current chromatography. | Journal of chromatography. A 20020118 |
Biosynthetic pathway to the cancer chemopreventive secoisolariciresinol diglucoside-hydroxymethyl glutaryl ester-linked lignan oligomers in flax (Linum usitatissimum) seed. | Journal of natural products 20011101 |
An oligomer from flaxseed composed of secoisolariciresinoldiglucoside and 3-hydroxy-3-methyl glutaric acid residues. | Phytochemistry 20011001 |
Secoisolariciresinol diglucoside from flaxseed delays the development of type 2 diabetes in Zucker rat. | The Journal of laboratory and clinical medicine 20010701 |