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Hydroquinidine HCl

CAS No.:
1476-98-8
Catalog Number:
AG001F0L
Molecular Formula:
C20H27ClN2O2
Molecular Weight:
362.8936
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
>98.0%(T)(HPLC)
1 week
United States
$227
- +
250g
>98.0%(T)(HPLC)
1 week
United States
$1087
- +
Product Description
Catalog Number:
AG001F0L
Chemical Name:
Hydroquinidine HCl
CAS Number:
1476-98-8
Molecular Formula:
C20H27ClN2O2
Molecular Weight:
362.8936
MDL Number:
MFCD00135598
IUPAC Name:
(S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;hydrochloride
InChI:
InChI=1S/C20H26N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3;1H/t13-,14-,19+,20-;/m0./s1
InChI Key:
MULXTQKDWYBJMO-VJAUXQICSA-N
SMILES:
CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](c1ccnc2c1cc(OC)cc2)O.Cl
EC Number:
216-024-1
UNII:
6BR4G8VAHM
Properties
Complexity:
432  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
362.176g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
362.898g/mol
Monoisotopic Mass:
362.176g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
45.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Modified asymmetric Strecker reaction of aldehyde with secondary amine: a protocol for the synthesis of S-clopidogrel (an antiplatelet agent). The Journal of organic chemistry 20120817
[Malignant fascicular ventricular tachycardia degenerating into ventricular fibrillation in a patient with early repolarization syndrome]. Annales de cardiologie et d'angeiologie 20120801
Multifocal ectopic Purkinje-related premature contractions: a new SCN5A-related cardiac channelopathy. Journal of the American College of Cardiology 20120710
A novel hydroquinidine imprinted microsphere using a chirality-matching N-acryloyl-L-phenylalanine monomer for recognition of cinchona alkaloids. Journal of chromatography. A 20120518
Metabolism of 2-chloro-4-nitrophenol in a gram negative bacterium, Burkholderia sp. RKJ 800. PloS one 20120101
Short QT syndrome in infancy. Therapeutic drug monitoring of hydroquinidine in a newborn infant. British journal of clinical pharmacology 20111201
Catalytic enantioselective protonation of enol trifluoroacetates by means of hydrogenocarbonates and cinchona alkaloids. The Journal of organic chemistry 20110805
Long-term follow-up of patients with short QT syndrome. Journal of the American College of Cardiology 20110802
Inline pneumatically assisted atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry. Journal of mass spectrometry : JMS 20100601
Determination of nicardipine and amlodipine in human plasma using on-line solid-phase extraction with a monolithic weak cation-exchange column. Talanta 20090115
Characterization of phenoloxidase activity in Sydney rock oysters (Saccostrea glomerata). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20071201
A clinical trial of topical bleaching treatment with nanoscale tretinoin particles and hydroquinone for hyperpigmented skin lesions. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20070801
Calculation of standard electrode potential of half reaction for benzoquinone and hydroquinone. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061001
Monomorphic ventricular tachycardia due to Brugada syndrome successfully treated by hydroquinidine therapy in a 3-year-old child. Journal of cardiovascular electrophysiology 20060101
Hydroquinidine therapy in Brugada syndrome. Journal of the American College of Cardiology 20040519
Short QT syndrome: pharmacological treatment. Journal of the American College of Cardiology 20040421
[Adverse drug reactions in three older patients, even without changes in medication]. Nederlands tijdschrift voor geneeskunde 20030329
Proliferation and morphological transformation of RMK cells exposed to hydroquinine containing ionomers. Biomedical sciences instrumentation 20020101
Safety and effectiveness of oral quinidine in cardioversion of persistent atrial fibrillation. Journal of cardiology 20011201
Plasma concentrations of quinidine, its major metabolites, and dihydroquinidine in patients with torsades de pointes. Clinical pharmacology and therapeutics 19880601
Properties